235 results on '"Hermanns, Henning"'
Search Results
2. The effectiveness of ambulatory continuous popliteal sciatic nerve blockade on patient-reported overall benefit of analgesia in patients undergoing foot or ankle surgery (CAREFREE trial); a randomized, open label, non-inferiority trial
- Author
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Admiraal, Manouk, Smulders, Pascal S.H., Rutten, Martin V.H., de Groot, Eelko K., Heine, Yvonne, Baumann, Holger M., van der Vegt, Vincent H.C., Halm, Jens A., Hermanns, Henning, Schepers, Tim, Hollmann, Markus W., Hermanides, Jeroen, and ten Hoope, Werner
- Published
- 2024
- Full Text
- View/download PDF
3. The effectiveness of a transitional pain service in patients undergoing surgery with an increased risk of developing chronic postsurgical pain (TRUSt study). A randomized clinical trial
- Author
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Admiraal, Manouk, Hermanides, Jeroen, Meinsma, Soe L., Wartenberg, Hans C.H., Rutten, Martin V.H., Heine, Yvonne, Kallewaard, Jan Willem, Hollmann, Markus W., and Hermanns, Henning
- Published
- 2023
- Full Text
- View/download PDF
4. International Survey on Perioperative Management of Patients With Infective Endocarditis
- Author
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Breel, Jennifer S., Eberl, Susanne, Preckel, Benedikt, Huhn, Ragnar, Hollmann, Markus W., Rex, Steffen, and Hermanns, Henning
- Published
- 2023
- Full Text
- View/download PDF
5. The Effect of Preoperative Disability, Cognitive Impairment, Frailty and Opioid Use on Acute Postoperative Pain in Older Patients Undergoing Surgery A Prospective Cohort Study
- Author
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Admiraal, Manouk, van Zuylen, Mark L., Hermanns, Henning, Willems, Hanna C., Geurtsen, Gert J., Steegers, Monique A.H., Kallewaard, Jan Willem, Hollmann, Markus W., and Hermanides, Jeroen
- Published
- 2023
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- View/download PDF
6. The Options for Neuraxial Drug Administration
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Hermanns, Henning, Bos, Elke M. E., van Zuylen, Mark L., Hollmann, Markus W., and Stevens, Markus F.
- Published
- 2022
- Full Text
- View/download PDF
7. Cerebral Glucose Metabolism following TBI: Changes in Plasma Glucose, Glucose Transport and Alternative Pathways of Glycolysis—A Translational Narrative Review
- Author
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Gribnau, Annerixt, primary, van Zuylen, Mark L., additional, Coles, Jonathan P., additional, Plummer, Mark P., additional, Hermanns, Henning, additional, and Hermanides, Jeroen, additional
- Published
- 2024
- Full Text
- View/download PDF
8. Differences in the Incidence of Hypotension and Hypertension between Sexes during Non-Cardiac Surgery: A Systematic Review and Meta-Analysis
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Bos, Elke M. E., primary, Tol, Johan T. M., additional, de Boer, Fabienne C., additional, Schenk, Jimmy, additional, Hermanns, Henning, additional, Eberl, Susanne, additional, and Veelo, Denise P., additional
- Published
- 2024
- Full Text
- View/download PDF
9. Different Analgesia Techniques for Postoperative Pain in Children Undergoing Abdominal Surgery for Intractable Constipation: A Retrospective Cohort Study in a Single Tertiary Children’s Hospital
- Author
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Admiraal, Manouk, primary, van der Burg, Fleur A. E., additional, Hermanns, Henning, additional, Hermanides, Jeroen, additional, Hollmann, Markus W., additional, Benninga, Marc A., additional, de Jong, Justin, additional, Gorter, Ramon R., additional, and Stevens, Markus F., additional
- Published
- 2024
- Full Text
- View/download PDF
10. Transesophageal echocardiography during surgery of the thoracic aorta in adults
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Alberts, Tim, primary, Eberl, Susanne, additional, and Hermanns, Henning, additional
- Published
- 2023
- Full Text
- View/download PDF
11. Molecular mechanisms of action of systemic lidocaine in acute and chronic pain: a narrative review
- Author
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Hermanns, Henning, Hollmann, Markus W., Stevens, Markus F., Lirk, Philipp, Brandenburger, Timo, Piegeler, Tobias, and Werdehausen, Robert
- Published
- 2019
- Full Text
- View/download PDF
12. Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study
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Abad Gurumeta, Alfredo, Abernethy, Caroline, Abigail, Patrick, Achaibar, Kira, Adam, Emily, Afshari, Arash, Agudelo Montoya, M. Elizabeth, Akgün, Fatma Nur, Aletti, Gabriele, Alkış, Neslihan, Allan, Katie, Allan, Ashley, Allaouchiche, Bernard, Allcock, Clare, Almasy, Emoke, Amey, Isobel, Amigoni, Maria, Andersen, Elin, Andersson, Peder, Anipchenko, Natalya, Antunes, Pedro, Armstrong, Earlene, Aslam, Tayyba Naz, Aslin, Bjorn, Assunção, José Pedro, Ausserer, Julia, Avvai, Mary, Awad, Nahla, Ayas Montero, Begoña, Ayuso, Mercedes, Azevedo, Patricia, Badarau, Victoria, Badescu, Roxana, Baiardo Redaelli, Martina, Baird, Colin, Baird, Yolanda, Baker, Tim, Balaji, Packianathaswamy, Bălan, Cristina, Balandin, Alina, Balescu-Arion, Carmen, Baliuliene, Vilda, Baltasar Isabel, Jorge, Baluch, Saif Nasr, Bandrabur, Daniela, Bankewitz, Carla, Barber, Katrina, Barbera, Francesco, Barcraft-Barnes, Helena, Barletti, Valentina, Barnett, Gill, Baron, Kirsty, Barros, Ana, Barsan, Victoria, Bartlett, Pauline, Batistaki, Chrysanthi, Baumgarten, Georg, Baytas, Volkan, Beauchamp, Nigel, Becerra Cayetano, Isabel A., Bell, Stephanie, Bellandi, Mattia, Belletti, Alessandro, Belmonte Cuenca, Julio, Benitez-Cano, Adela, Beretta, Luigi, Berger, Marc, Bergmann, Nicole, Bergmark, Kristina, Bermudez Lopez, Maria, Bernotaite, Monika, Beurskens, Charlotte, Bidd, Heena, Bifulco, Francesca, Bignami, Elena, Bilic, Aleksandar, Bilskiene, Diana, Bischoff, Petra, Bishop, Luke, Bjonness, Therese, Blaylock, Hether, Blethyn, Kate, Blincoe, Thomas, Blokhin, Ivan, Blunt, Nadia, Boer, Christa, Bois, Grégory, Bonicolini, Eleonora, Booth, Joanna, Borecka-Kedzierska, Miroslawa, Borstnar, Katarina, Borys, Michał, Boselli, Emmanuel, Bouvet, Lionel, Bouwman, Arthur, Bowen, Leonora, Bowrey, Sarah, Boxall, Leigh, Božić, Teodora, Bradley, Tom, Branco, Teresa, Brazzi, Luca, Brazzoni, Marcella, Brear, Tracy, Brogly, Nicolas, Brohi, Farooq, Broms, Jacob, Bubliauskas, Andrius, Bucolo, Gea Erika, Buerkle, Hartmut, Buggy, Donal, Buhre, Wolfgang, Bukauskas, Tomas, Butturini, Francesco, Byttner, Anders, Cabrera Díaz, Itahísa, Calderon, Adriana, Calhau, Ricardo, Callejo, Angel, Cammu, Guy, Campesato, Manuela, Can, Özlem S, Candeias, Margarida, Cantor, Andreea, Carise, Elsa, Carmona, Cristina, Carreteiro, Joana, Carrieri, Cosima, Carter, Anna, Casal, Manuela, Casanova, Irene, Cascella, Marco, Casero, Luis M., Casiraghi, Guiseppina Maria, Castelo-Branco, Laila, Castro Arranz, Carlos, Cernea, Daniela Denisa, Cervantes, Jesoporiol, Chandler, Ben, Charnock, Robert, Chatzimicali, Aikaterini, Chinery, Elane, Chishti, Ahmed, Chondhury, Priyakam, Christie, Emily, Christodoudiles, George, Ciardo, Stefano, Cimpeanu, Luminata, Cindea, Iulia, Cinnella, Gilda, Clark, Sebastian, Clayton, Matthew, Cocu, Simona, Collyer, Thomas, Colvin, Carie, Cope, Sean, Copeta, Filomena, Copotoiu, Sanda-Maria, Correia de Barros, Filinto, Corso, Ruggero Massimo, Cortegiani, Andrea, Costa, Gabriela, Cowton, Amanda, Cox, Nicolas, Craig, James, Cricca, Valentina, Cronin, John, Cunha, Mariana, Cuomo, Arturo, Curley, Katherine, Czuczwar, Mirosław, Dabrowska, Domenika, Damster, Sabrine, Danguy des Déserts, Marc, Daniliuc, Aura, Danninger, Thomas, Darwish, Imad, Dascalu, Corina, Davies, Kirsty, Davies, Simon, De Boer, Hans, De Flaviis, Adelisa, De Selincourt, Gabrielle, Deana, Cristian, Debaene, Bertrand, Debreceni, Gabor, Dedhia, Jatin, Delgado Garcia, Isabel, Della Rocca, Giorgio, Delroy-Buelles, Llana, Desai, Tejal, Dhillon, Parveen, Di Giacinto, Ida, Di Mauro, Piero, Diaz Gomez, Tamara V., Dimitrovski, Aleksandar, Dinic, Vesna, Dîrzu, Dan-Sebastian, Divander, Mona Britt, Dolinar, Janez, Domingues, Susana, Doolan, James, Downes, Charlotte, Dragoescu, Nicoleta Alice, Droc, Gabriela, Dum, Elisabeth, Dumitrescu, Alexandra, Duncan, Louise, Dzurňáková, Paul, Eberl, Susanne, Edwards, Jayne, Edwards, Mark, Ekelund, Kim, Ekengren, Patrik, Elghouty, Eyad, Ellerkmann, Richard, Ellis, Helen, Elme, Andreas, Ernst, Thomas, Errando, Carlos Luis, Estenes, Simao, Ewaldsson, Callis, Farid, Nahla, Featherstone, James, Febres, Daniela, Fedorov, Sergey, Feggeler, Johanna, Feijten, Prisca, Fellmann, Tobias, Fernandez Candil, Juan, Fernandez Castineira, Ana, Fernández Castineira, Juan, Fernando, Aruna, Ferrando, Carlos, Ferreira, Leonia, Ferreira, Patrick, Feyling, Anders, Filipescu, Daniela, Fleischer, Andreas, Floris, Leda, Foerster, Urs, Fox, Benjamin, Franke, Uwe, Frasca, Denis, Frey, Christian, Frost, Victoria, Fullin, Giorgio, Fumagalli, Jacopo, Furneval, Julie, Fusari, Maurizio, Gallacher, Stuart, Galushka, Svetlana, Gambale, Giorgio, Gambino, Irene, Garcia-Perez, Maria Luisa, Garg, Sanjeev, Garlak, Justyna, Gavranovic, Zeljka, Gavrilov, Roman, Gaynor, Lames, Gecaj Gashi, Agreta, Georghiou, Maria, Gerjevic, Bozena, Gferer, Gudrun, Giarratano, Antonino, Gibson, Andy, Gievski, Vanja, Giles, Julian, Gillberg, Lars, Gilowska, Katarzyna, Gilsanz Rodriguez, Fernando, Gioia, Antonio, Giovannoni, Cecilia, Girotra, Vandana, Gkinas, Dimitrios, Gkiokas, George, Godoroja, Daniela, Goebel, Ulrich, Goel, Vandana, Gonzalez, Matilde, Goranovic, Tatjana, Gornik-Wlaszczuk, Ewa, Gosavi, Smita, Gottfridsson, peter, Gottschalk, André, Granell, Manuel, Granstrom, Anna, Grassetto, Alberto, Greenwood, Anna, Grigoras, Ioana, Grintescu, Ioana, Gritsan, Alexey, Gritsan, Galina, Grynyuk, Andriy, Guadagnin, Giovanni Maria, Guarnieri, Marcello, Güçlü, Çiğdem, Guerrero Diez, Maria, Gunenc, Ferim, Günther, Ulf, Gupta, Pawan, Guttenthaler, Vera, Hack, Yvonne, Hafisayena, Ade, Hagau, Natalia, Haldar, Jagannath, Hales, Dawn, Hancı, Volkan, Hanna-Jumma, Sameer, Harazim, Hana, Harlet, Pierre, Harper, Daniel, Harris, Benjamin, Harvey, Orla, Hashimi, Medita, Hawkins, Lesley, Hayes, Conrad, Heaton, James, Heier, Tom, Helliwell, Laurence, Hemmes, Sabrine, Henderson, Kate, Hermanides, Jeroen, Hermanns, Henning, Herrera Hueso, Berta, Hestenes, Siv, Hettiarachchi, Roshane, Highgate, Judith, Hodgson, Keith, Hoelbling, Daniel, Holland, Jonathan, Horhota, Lucian, Hormis, Anil, Hribar, Renata, Hua, Alina, Humphreys, Sally, Humphries, Ryan, Humpliková, Simona, Hunt, Janez, Husnain, Ali, Hussein, Ahmed, Hyams, Benjamin, Iannuccelli, Fabrizio, Ilette, Katie, Ilyas, Carl, Inan, Turgay, India, Immaculada, Ionițăv, Victor, Irwin, Foo, Jain, Vipul, Janez, Benedikt, Jankovic, Radmilo, Jenkins, Sarah, Jenko, Matej, Jimenez, Raquel, Jiménez Gomez, Bárbara, Joachim, Sugganthi, Joelsson-Alm, Eva, John, John, Jonikaite, Lina, Jovic, Miomir, Jungwirth, Bettina, Junke, Etienne, Kabakov, Borys, Kadaoui, Salah-Din, Kanski, Andrzej, Karadag, Süheyla, Karbonskiene, Aurika, Karjagin, Juri, Kasnik, Darja, Katanolli, Fatos, Katsika, Eleni, Kaufmann, Kai, Keane, Helen, Kelly, Martin, Kent, Melanie, Keraitiene, Grazina, Khudhur, Ahmed, Khuenl-Brady, Karin, Kidd, Laurie, King, Siobhan, Kirchgäßner, Katharina, Klancir, Tino, Klucniks, Andris, Knotzer, Johann, Knowlden, Peter, Koers, Lena, Kompan, Janez, Koneti, Kiran K, Kooij, Fabian, Koolen, Eric, Koopman - van Gemert, Anna Wilhelmina Margaretha Maria, Kopp, Kristen, Korfiotis, Dimitrios, Korolkov, Oleg, Kosinová, Martina, Köstenberger, Markus, Kotzinger, Oskar, Kovačević, Marko, Kranke, Peter, Kranke, Eva, Kraus, Christiane, Kraus, Stephanie, Kubitzek, Christiane, Kucharski, Rafal, Kucukguclu, Semih, Kudrashou, Allaksandr, Kumar, Vinayak, Kummen, Live, Kunit, Cornelia, Kushakovsky, Vlad, Kuvaki, Bahar, Kuzmanovska, Biljana, Kyttari, Aikaterina, Landoni, Giovanni, Lau, Gary, Lazarev, Konstantin, Legett, Samantha, Legrottaglie, Anna Maria, Leonardi, Silvia, Leong, Maria, Lercher, Helene, Leuvrey, Matthieu, Leva, Brigitte, Levstek, Meta, Limb, James, Lindholm, Espen, Linton, Fiona, Liperi, Corradero, Lipski, Fabian, Lirk, Philipp, Lisi, Alberto, Lišková, Katarina, Lluch Oltra, Aitana, Loganathan, Vinothan, Lombardi, Stefania, Lopez, Eloisa, Lopez Rodríguez, Maria, Lorenzini, Laura, Lowicka, Malgorzata, Lugovoy, Alexander, Luippold, Madeleine, Lumb, Andrew, Macas, Andrius, Macgregor, Mark, Machado, Humberto, Maciariello, Maria, Madeira, Isabel, Maitan, Stefan, Majewski, Jacek, Maldini, Branka, Malewski, Georgia, Manfredini, Livia, Männer, Olja, Marchand, Bahareh, Marcu, Alexandra, Margalef, Jordi, Margarson, Michael, Marinheiro, Lucia, Markic, Ana, Markovic Bozic, Jasmina, Marrazzo, Francesco, Martin, Jane, Martin Ayuso, Maria, Martinez, Esteher, Martino, Enrico Antonio, Martinson, Victoria, Marusic-Gaser, Katarina, Mascarenhas, Catia, Mathis, Cindy, Matsota, Paraskevi, Mavrommati, Eleni, Mazul Sunko, Branka, McCourt, Killian, McGill, Neil, McKee, Raymond, Meço, Başak Ceyda, Meier, Sonja, Melbourne, Susan, Melbybråthen, Grethe, Meli, Andrea, Melia, Aiden, Melotti, Rita Maria, Menga, Maria Rosaria, Mercer, Pauline, Merotra, Susan, Mescolini, Silvia, Metterlein, Thomas, Michalov, Martin, Michlig, Sam, Midgley, Susan, Milić, Morena, Milojevic, Milan, Miñana, Amanda, Minto, Gary, Mirabella, Lucia, Mirea, Liliana, Mittelstädt, Ludger, Moeglen, Aude, Moise, Alida, Mokini, Zhirajr, Molin, Anna, Moltó, Luis, Monea, Maria Concetta, Montalto, Francesca, Montgomery, Jane, Montgomery, Claire, Montillo, Gerardo, Moore, Sally, Moore, Faye, Moreira, Zelia, Moreno, Tania, Moreno, Ricardo, Moret, Enrique, Moreton, Sarah, Morgan, Marianne, Moro Velasco, Concepción, Morri, Davide, Moull, Alice, Moura, Fernando, Mráz, Peter, Mrozek, Katarzyna, Mukhtar, Karim, Muniyappa, Sudeshkumar, Murray, Heather, Murthy, Burra VS, Mushambi, Mary, Nadolski, Maria, Nardelli, Pasquale, Nardin, Giordano, Navarro Pérez, Rosalía, Naveiro, Andrea, Negri, Manuela, Nesek Adam, Visnja, Neskovic, Vojislava, Neuwersch, Stefan, Neves, Miriam, Nguyen, Bavinh, Ní Eochagáin, Aisling, Nicholas, Caroline, Nightingale, Jeremy, Norrie, Kylie, Novak-Jankovic, Vesna, Novakova, Andrea, Novillo, Marta, Numan, Sandra, Oduro-Dominah, Louise, Oldner, Anders, Oliveira, Isabel, Ologoiu, Daniela, Oloktsidou, Irini, O'Reilly, Rosalind, Orlando, Alessandro, Ovezov, Alexey, Ozbilgin, Sule, Paal, Peter, Padin Barreiro, Lidia, Palugniok, Ryszard, Papaioannou, Alexandra, Papapostolou, Konstantinos, Paranthaman, Prabhakar, Pardey Bracho, Gilda, Parente, Suzana, Parfeni, Alexandru, Pasin, Laura, Passey, Samuel, Pastor, Ernesto, Patch, Sarah, Patil, Andan, Paunescu, Marilena-Alina, Pehboeck, Daniel, Pereira, Manuela, Pereira, Carla, Perez Caballero, Paula, Pérez García, Aníbal, Pérez Soto, Antonia, Perez Tejero, Gisela, Perez-Cerda, Francisco, Pesenti, Antonio, Petta, Rocco, Philippe, Simon, Pickering, David, Pico Veloso, Jandro, Pina, Pedro, Pinho-Oliveira, Vítor, Pinol, Santiago, Pinto, Rita, Pistidda, Laura, Pitterle, Manuela, Piwowarczyk, Paweł, Plotnikova, Olga, Pohl, Holger, Poldermann, Jorinde, Polkovicová, Lucia, Pompei, Livia, Popescu, Mihai, Popović, Radmila, Pota, Vincenzo, Potocnik, Miriam, Potręć, Beata, Potter, Alison, Pramod, Nalwaya, Prchalova, Martina, Preckel, Benedikt, Pugh, Richard, Pulletz, Mark, Radoeshki, Aleksandar, Rafi, Amir, Ragazzi, Riccardo, Raineri Santi, Maurizio, Rajamanickam, Tamiselvan, Rajput, Zahra, Ramachandran, Rajeskar, Ramasamy, Radhika, Ramessur, Suneil, Rao, Roshan, Rasmussen, Anders, Rato, André, Razaque, Usman, Real Navacerrada, M. Isabel, Reavley, Caroline, Reid, James, Reschreiter, Henrik, Rial, Erick, Ribas Carrasco, Patricia, Ribeiro, Sandy, Rich, Nathalie, Richardson, Lydia, Rimaitis, Kestutis, Rimaitis, Marius, Ringvold, Else-Marie, Ripke, Fabian, Ristescu, Irina, Ritchie, Keith, Ródenas, Frederic, Rodrigues, Patrícia, Rogers, Emma, Rogerson, David, Romagnoli, Stefano, Romero, Esther, Rondovic, Goran, Rose, Bernd Oliver, Roth, Winfried, Rotter, Marie-Therese, Rousseau, Guy, Rudjord, Anders, Rueffert, Henrik, Rundgren, Malin, Rupprecht, Korbinian, Rushton, Andrew, Russotto, Vincenzo, Rypulak, Elżbieta, Ryszka, Maciej, Sà, Jacinta, Sà Couto, Paula, Saby, Sandrine, Sagic, Jelena, Saleh, Omar, Sales, Gabriele, Sánchez Sánchez, Yván, Sanghera, Sumayer, Şanli Karip, Ceren, Santiveri Papiol, Francisco Javier, Santos, Sofia, Sarno, Stephen, Saul, Daniel, Saunders, David, Savic, Nenad, Scalco, Loïc, Scanlon, Deborah, Schaller, Stefan, Schax, Christoph, Scheffer, Gert Jan, Schening, Anna, Schiavone, Vincenzo, Schmidt-Ehrenberg, Florian, Schmidt-Mutter, Catherine, Schönberg, Christina, Schopflin, Christian, Schreiber, Jan-Uwe, Schultz, Marcus, Schurig, Marlen, Scott, Carmen, Sebestian, Siby, Sehgal, Selena, Sem, Victoria, Semenas, Egidijus, Serafini, Elena, Serchan, Pashalitsa, Shields, Martin, Shobha, Ramakrishnan, Shosholcheva, Mirjana, Siamansour, Tanja, Siddaiah, Narendra, Siddiqi, Khalid, Sinclair, Rhona, Singh, Permendra, Singh, Rajendra, Sinha, Aneeta, Sinha, Ashok, Skinner, Amanda, Smee, Elizabeth, Smekalova, Olga, Smith, Neil, Smith, Thomas, Smitz, Carine, Smole, Daniel, Sojčić, Nataša, Soler Pedrola, Maria, Somanath, Sameer, Sonksen, Julian, Sorella, Maria Christina, Sörmus, Alar, Soro, Marina, Soto, Carmen, Spada, Anna, Spadaro, Savino, Spaeth, Johannes, Sparr, Harald, Spielmann, Annika, Spindler-Vesel, Alenka, Stamelos, Matthaios, Stancombe L, Liucia, Stanculescu, Andreea, Standl, Thomas, Standley, Tom, Stanek, Ondrej, Stanisavljević, Snežana, Starczewska, Malgorzata, Stäuble, Christiane, Steen, Julie, Stefan, Oana Maria, Stell, Elizabeth, Stera, Caterina, Stevens, Markus, Stoerckel, Marlène, Stošić, Biljana, Stourac, Petr, Stroumpoulis, Konstantinos, Struck, Rafael, Suarez de la Rica, Alejandro, Sultanpori, Altaf, Sundara Rajan, Rajinikanth, Suying, Ong, Svensen, Christer, Swan, Louise, Syrogianni, Paulina, Sysiak, Justyna, Szederjesi, Janos, Taddei, Stefania, Tan Hao, Ern, Tanou, Virginia, Tarabová, Katarina, Tardaguila Sancho, Paula, Tarroso, Maria, Tartaglione, Marco, Taylor, Emma, Tbaily, Lee, Telford, Richard, Terenzoni, Massimo, Theodoraki, Kassiani, Thornley, Helen, Tiganiuc, Liviu, Toim, Hardo, Tomescu, Dana, Tommasino, Concezione, Toni, Jessica, Toninelli, Arturo, Toretti, Ilaria, Townley, Stephen, Trepenaitis, Darius, Trethowan, Brian, Tsaousi, Georgia, Tsiftsi, Aikaterini, Tudor, Adrada, Turan, Güldem, Turhan, Sanem Çakar, Unic-Stojanovic, Dragana, Unterbuchner, Christoph, Unzueta, Carmen, Uranjek, Jasna, Ursic, Tomaz, Vaida, Simona, Valldeperas Ferrer, Silvia, Valldeperas Hernandez, Maria Inmaculada, Valsamidis, Dimitri, Van Beek, Rienk, Van dasselaer, Nick, Van Der Beek, Tim, Van Duivenvoorde, Yoni, van Klei, Wilton A., Van Poorter, Frans, Van Zaane, Bas, Van Zundert, Tom, Van Zyl, Rebekka, Vargas Munoz, Ana Milena, Varsani, Nimu, Vasconcelos, Pedro, Vassilakis, Georgios, Vecchiatini, Tommaso, Vecera, Lubomir, Vercauteren, Marcel, Verdouw, Bas, Verheyen, Veerle, Verri, Marco, Vicari Sottosanti, Luigi Giancarlo, Vico, Manuel, Vidal Mitjans, Patricia, Vilardi, Anna, Vissicchio, Daniela, Vitale, Giovanni, Vitković, Bibiana, Vizcaychipi, Marcela Paola, Voicu, Alexandra, Voje, Minca, Volfová, Ivana, Volta, Carlo Alberto, Von Lutterotti, Theresa, von Tiesenhausen, Anna, Vrecic-Slabe, Simona, Vukcevic, Dejan, Vukovic, Rade, Vullo, P. Agostina, Wade, Andrew, Wallberg, Hanna, Wallden, Jakob, Wallner, Johann, Walther Sturesson, Louise, Watson, Davina, Weber, Stefan, Wegiel Leskiewiq, Anna, Weller, Debbie, Wensing, Carine, Werkmann, Markus, Westberg, Henrik, Wikström, Erik, Williams, Benedict, Wilson, Robin, Wirth, Steffen, Wittmann, Maria, Wood, Laura, Wright, Stella, Zachoval, Christian, Zambon, Massimo, Zampieri, Silvia, Zampone, Salvatore, Zangrillo, Alberto, Zani, Gianluca, Zavackiene, Asta, Zieglerder, Raphael, Zonneveldt, Harry, Zsisku, Lajos, Zucker, Tom-Philipp, Żukowski, Maciej, Zuleika, Mehrun, Zupanĕiĕ, Darja, Kirmeier, Eva, Eriksson, Lars I, Lewald, Heidrun, Jonsson Fagerlund, Malin, Hoeft, Andreas, Hollmann, Markus, Meistelman, Claude, Hunter, Jennifer M, Ulm, Kurt, and Blobner, Manfred
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- 2019
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13. What Really Matters to Survivors of Acute Type A Aortic Dissection—A Survey of Patient-Reported Outcomes in the Dutch National Aortic Dissection Advocacy Group
- Author
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Breel, Jennifer S., primary, de Klerk, Eline S., additional, Strypet, Magnus, additional, de Heer, Frederiek, additional, Hermanns, Henning, additional, Hollmann, Markus W., additional, and Eberl, Susanne, additional
- Published
- 2023
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14. The Effectiveness of Adductor Canal Block Compared to Femoral Nerve Block on Readiness for Discharge in Patients Undergoing Outpatient Anterior Cruciate Ligament Reconstruction: A Multi-Center Randomized Clinical Trial
- Author
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ten Hoope, Werner, primary, Admiraal, Manouk, additional, Hermanides, Jeroen, additional, Hermanns, Henning, additional, Hollmann, Markus W., additional, Lirk, Philipp, additional, Kerkhoffs, Gino M. M. W., additional, Steens, Jeroen, additional, and van Beek, Rienk, additional
- Published
- 2023
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15. Perioperative Complications in Infective Endocarditis
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Hermanns, Henning, primary, Alberts, Tim, additional, Preckel, Benedikt, additional, Strypet, Magnus, additional, and Eberl, Susanne, additional
- Published
- 2023
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16. Importance of Comprehensive Transesophageal Echocardiography Examination in a Patient With Infective Endocarditis of the Mitral Valve
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Fraessdorf, Jan, primary, Klautz, Robert J.M., additional, and Hermanns, Henning, additional
- Published
- 2023
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17. A multimodal pain protocol for treatment of vaso‐occlusive crisis in patients with sickle cell disease: Implementation and evaluation
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Admiraal, Manouk, primary, van Daalen, Jonathan, additional, Ritt, Michael W. J., additional, Dekker, Joost, additional, van Tuijn, Charlotte F. J., additional, Nur, Erfan, additional, Hollmann, Markus W., additional, Hermanns, Henning, additional, Hermanides, Jeroen, additional, and Biemond, Bart J., additional
- Published
- 2023
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18. Effect of the machine learning-derived Hypotension Prediction Index (HPI) combined with diagnostic guidance versus standard care on depth and duration of intraoperative and postoperative hypotension in elective cardiac surgery patients: HYPE-2 – study protocol of a randomised clinical trial
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Rellum, Santino R, primary, Schuurmans, Jaap, additional, Schenk, Jimmy, additional, van der Ster, Björn J P, additional, van der Ven, Ward H, additional, Geerts, Bart F, additional, Hollmann, Markus W, additional, Cherpanath, Thomas G V, additional, Lagrand, Wim K, additional, Wynandts, Paul, additional, Paulus, Frederique, additional, Driessen, Antoine H G, additional, Terwindt, Lotte E, additional, Eberl, Susanne, additional, Hermanns, Henning, additional, Veelo, Denise P, additional, and Vlaar, Alexander P J, additional
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- 2023
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19. Microbiological and scanning electron microscopic evaluation of epidural catheters
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van Samkar, Ganapathy, Balraadjsing, Payal P S, Hermanns, Henning, Hoogendijk, Irene V, Hollmann, Markus W, Zaat, Sebastian A J, and Stevens, Markus F
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- 2020
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20. Patients with infective endocarditis undergoing cardiac surgery have distinct ROTEM profiles and more bleeding complications compared to patients without infective endocarditis
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Breel, Jennifer S., primary, Wensing, Agnes G. C. L., additional, Eberl, Susanne, additional, Preckel, Benedikt, additional, Schober, Patrick, additional, Müller, Marcella C. A., additional, Klautz, Robert J. M., additional, Hollmann, Markus W., additional, and Hermanns, Henning, additional
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- 2023
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21. Face and construct validity of TU-Delft epidural simulator and the value of real-time visualization
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Zivkovic, Nenad, van Samkar, Ganapathy, Hermanns, Henning, Lirk, Philipp, Hollmann, Markus W, van den Dobbelsteen, John J, van Gerwen, Dennis J, and Stevens, Markus F
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- 2019
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22. Evaluation of Health Care Providers Satisfaction with the Implementation of a Transitional Pain Service
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Admiraal, Manouk, primary, Hermanides, Jeroen, additional, Hollmann, Markus W., additional, and Hermanns, Henning, additional
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- 2023
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23. Comparison of Patient-Controlled versus Continuous Epidural Analgesia in Adult Surgical Patients: A Systematic Review.
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van Samkar, Ganapathy, Ru Tan, Yan, Hermanns, Henning, Preckel, Benedikt, Jamaludin, Faridi S., Hollmann, Markus W., and Stevens, Markus F.
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EPIDURAL analgesia ,PATIENT-controlled analgesia ,PATIENT satisfaction ,ADULTS ,PAIN management ,POSTOPERATIVE pain - Abstract
Background: The advantages of PCEA over CEA have been demonstrated in obstetric patients. Whether a similar benefit applies to surgical patients is unclear. Methods: Embase, PubMed, and Cochrane Library were searched, enabling a systematic review of studies comparing PCEA and CEA in adult surgical patients (PROSPERO: CRD42018106644). The study quality was assessed using the Cochrane risk-of-bias tool (RoB2). The primary outcome was pain scores on postoperative day one (POD1). Secondary outcomes were 24 or 48 h epidural or intravenous total analgesic dose, systemic analgesics, manual top-ups, side effects, and patient satisfaction. Results: Six randomized controlled trials with high heterogeneity of study characteristics were identified with a moderate risk of bias. Two studies showed significantly reduced resting pain scores on POD1 in PCEA compared with CEA patients (36–44%, p < 0.05). Four studies found comparable pain scores between these groups. PCEA use reduced epidural medication (28% to 40% reduction, p < 0.01) in four studies. One study found a 23% reduction (p < 0.001) of top-ups in PCEA; intravenous morphine use by PCEA patients was reduced (0.16 vs. 3.45 mg per patient, p < 0.05) in one study. PCEA patients were more satisfied with analgesia (p < 0.001) in two studies. Nausea and vomiting were reduced in PCEA (p = 0.01). Conclusions: Regarding the reduction in pain scores, the effects of PCEA were not significant or clinically not relevant. However, regarding the amount of epidural drug use, the amount of required rescue systemic analgesics, patient satisfaction, and the number of required top-ups, PCEA had advantages over CEA in surgical patients. [ABSTRACT FROM AUTHOR]
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- 2023
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24. Anesthesia Considerations in Infective Endocarditis
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Hermanns, Henning, primary, Eberl, Susanne, additional, Terwindt, Lotte E., additional, Mastenbroek, Thierry C. B., additional, Bauer, Wolfgang O., additional, van der Vaart, Thomas W., additional, and Preckel, Benedikt, additional
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- 2022
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25. A quadricuspid aortic valve with fibrous strand rupture.
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Hermanns, Henning and Driessen, Antoine H G
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AORTIC valve ,AORTIC valve insufficiency ,BUNDLE-branch block - Published
- 2024
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26. Current multidisciplinary approaches to preventing chronic postoperative pain
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Admiraal, Manouk, primary, Hermanides, Jeroen, additional, Meinsma, Soe L., additional, Wartenberg, Hans C.H., additional, Rutten, Martin V.H., additional, Ward-van der Stam, Vivian M.C., additional, Hollmann, Markus W., additional, and Hermanns, Henning, additional
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- 2021
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27. Study protocol for the TRUSt trial: a pragmatic randomised controlled trial comparing the standard of care with a transitional pain service for patients at risk of chronic postsurgical pain undergoing surgery
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Admiraal, Manouk, primary, Hermanns, Henning, additional, Hermanides, Jeroen, additional, Wensing, Carin G.C.L., additional, Meinsma, Soe L., additional, Wartenberg, Hans C. H., additional, Rutten, Martin V. H., additional, Ward - van der Stam, Vivian M. C., additional, and Hollmann, Markus W., additional
- Published
- 2021
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28. Antinociceptive effects of systemic lidocaine: Involvement of the spinal glycinergic system
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Muth-Selbach, Uta, Hermanns, Henning, Stegmann, Jens Ulrich, Kollosche, Kathrin, Freynhagen, Rainer, Bauer, Inge, and Lipfert, Peter
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- 2009
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29. Mechanisms of nociception in neuropathic pain
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Hermanns, Henning, Hollmann, M.W., Stevens, M.F., Faculteit der Geneeskunde, Hollmann, Markus W., Stevens, Markus F., ACS - Diabetes & metabolism, ACS - Heart failure & arrhythmias, Anesthesiology, Graduate School, and APH - Quality of Care
- Abstract
Aim of this thesis was to explore the mechanisms that account for the development and maintenance of chronic neuropathic pain. This pain type, caused by a lesion to the somatosensory system, can be a debilitating clinical condition which is hard to treat. The shortcomings in current treatment are believed to be associated with the lack of knowledge on the pathogenesis of neuropathic pain. The first major subject of this thesis focusses on inhibitory mechanisms of pain, especially glycinergic neurotransmission, since spinal disinhibition is a central mechanism for hyperalgesia. In the experiments described in the thesis, a significant role of glycinergic transmission in neuropathic pain could be confirmed. Furthermore, the glycine transporters GlyT1 and GlyT2 could be identified as promising translational targets in the treatment of neuropathic pain. The second major subject of this thesis is the regulation of gene expression in neuropathic pain, specifically the involvement of microRNAs in the somatosensory nervous system. A wide variety of microRNAs possibly involved in the pathophysiology of neuropathic pain has been identified before. In the studies included in this thesis, two further microRNAs, microRNA-1 and microRNA-34a as well as their pain-relevant target proteins are described. Finally, the mechanisms by which systemic administration of the local anesthetic lidocaine can relieve acute and chronic pain are reviewed. The results obtained from the experiments in this thesis further enhance the knowledge on the molecular basis of the maladaptive processes of painful neuropathy, which may eventually lead to the development of new, mechanisms-oriented treatment options.
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- 2021
30. Clot Formation in Cardiopulmonary Bypass Circuit After Application of Factor XI Concentrate
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Hulsman, Niels, van der Meulen, Jan, Talacua, Hanna, Essoussi, Bachir, and Hermanns, Henning
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- 2020
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31. Intraneural application of microRNA-1 mimetic nucleotides does not resolve neuropathic pain after chronic constriction injury in rats
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Kuebart, Anne, Wollborn, Verena, Huhn, Ragnar, Hermanns, Henning, Werdehausen, Robert, Brandenburger, Timo, Anesthesiology, Graduate School, ACS - Diabetes & metabolism, ACS - Heart failure & arrhythmias, APH - Quality of Care, and Amsterdam Neuroscience - Neuroinfection & -inflammation
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MicroRNAs ,Peripheral nerve ,Chronic pain ,Journal of Pain Research ,Neuropathic pain ,Original Research - Abstract
Anne Kuebart,1,* Verena Wollborn,1,* Ragnar Huhn,1 Henning Hermanns,2 Robert Werdehausen,3 Timo Brandenburger1 1Department of Anesthesiology, University Hospital Düsseldorf, Medical Faculty, Düsseldorf 40225, Germany; 2Department of Anesthesiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; 3Department of Anesthesiology and Intensive Care, University of Leipzig, Medical Faculty, Leipzig 04103, Germany*These authors contributed equally to this workCorrespondence: Timo BrandenburgerDepartment of Anesthesiology, University Hospital Düsseldorf, Moorenstr. 5, Düsseldorf 40225, GermanyEmail timo.brandenburger@med.uni-duesseldorf.deRobert WerdehausenDepartment of Anesthesiology and Intensive Care, University of Leipzig, Medical Faculty, Leipzig 04103, GermanyEmail robert.werdehausen@medizin.uni-leipzig.deBackground: Alterations of the expression of microRNAs (miRNAs) in chronic pain models seem to play a crucial role in the development of neuropathic pain, with microRNA-1 (miR-1) being of particular interest. Recently, we were able to show that decreased miR-1 levels were associated with increased expression of brain-derived neurotrophic factor (BDNF) and Connexin 43 (Cx43). We hypothesized that miR-1 mimetic nucleotides could alleviate neuropathic pain caused by chronic constriction injury in rats.Methods: MiR-1 mimetic nucleotides were evaluated for effectiveness, functionality, and intracellular stability by transfecting human glioblastoma cells (U-87 MG). In vivo transfection with miR-1 mimics and corresponding scrambled miRNAs serving as control was performed by repetitive injection (days 0, 3, and 7) into the sciatic nerve following chronic constriction injury (CCI) in rats. Quantitative PCR was used to measure miR-1 content. Cx43 expression was determined by Western blot analysis. Effects on neuropathic pain were assessed by detecting paw withdrawal thresholds using an automated filament application.Results: Transfection of miR-1 mimics was confirmed in U-87 MG cells, with miR-1 content being increased significantly after 48 h and after 96 h (p< 0.05). Effective downregulation of Cx43 expression was observed 48 and 96 h after transfection (− 44 ± 0.07% and − 40 ± 0.11%; p< 0.05). In vivo, repetitive transfection with miR-1 mimetic nucleotides led to a 17.9-fold (± 14.2) increase of miR-1 in the sciatic nerve. However, the protein expression of Cx43 in sciatic nerves as well as paw withdrawal thresholds for mechanical stimulation was not significantly increased 10 days after chronic constriction injury.Conclusion: While transfection with miR-1 mimics effective reduces Cx43 expression in vitro and restores miR-1 after CCI, we did neither observe altered levels of Cx43 protein level in nerves nor a beneficial effect on mechanical allodynia in vivo, most likely caused by insufficient Cx43 suppression.Keywords: chronic pain, neuropathic pain, microRNAs, peripheral nerve
- Published
- 2020
32. Intraneural Application of microRNA-1 Mimetic Nucleotides Does Not Resolve Neuropathic Pain After Chronic Constriction Injury in Rats
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Kuebart,Anne, Wollborn,Verena, Huhn,Ragnar, Hermanns,Henning, Werdehausen,Robert, Brandenburger,Timo, Kuebart,Anne, Wollborn,Verena, Huhn,Ragnar, Hermanns,Henning, Werdehausen,Robert, and Brandenburger,Timo
- Abstract
Anne Kuebart,1,* Verena Wollborn,1,* Ragnar Huhn,1 Henning Hermanns,2 Robert Werdehausen,3 Timo Brandenburger1 1Department of Anesthesiology, University Hospital Düsseldorf, Medical Faculty, Düsseldorf 40225, Germany; 2Department of Anesthesiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; 3Department of Anesthesiology and Intensive Care, University of Leipzig, Medical Faculty, Leipzig 04103, Germany*These authors contributed equally to this workCorrespondence: Timo BrandenburgerDepartment of Anesthesiology, University Hospital Düsseldorf, Moorenstr. 5, Düsseldorf 40225, GermanyEmail timo.brandenburger@med.uni-duesseldorf.deRobert WerdehausenDepartment of Anesthesiology and Intensive Care, University of Leipzig, Medical Faculty, Leipzig 04103, GermanyEmail robert.werdehausen@medizin.uni-leipzig.deBackground: Alterations of the expression of microRNAs (miRNAs) in chronic pain models seem to play a crucial role in the development of neuropathic pain, with microRNA-1 (miR-1) being of particular interest. Recently, we were able to show that decreased miR-1 levels were associated with increased expression of brain-derived neurotrophic factor (BDNF) and Connexin 43 (Cx43). We hypothesized that miR-1 mimetic nucleotides could alleviate neuropathic pain caused by chronic constriction injury in rats.Methods: MiR-1 mimetic nucleotides were evaluated for effectiveness, functionality, and intracellular stability by transfecting human glioblastoma cells (U-87 MG). In vivo transfection with miR-1 mimics and corresponding scrambled miRNAs serving as control was performed by repetitive injection (days 0, 3, and 7) into the sciatic nerve following chronic constriction injury (CCI) in rats. Quantitative PCR was used to measure miR-1 content. Cx43 expression was determined by Western blot analysis. Effects on neuropathic pain were assessed by detecting paw withdrawal thresholds using an automated filament application.Result
- Published
- 2020
33. Skin Temperature After Interscalene Brachial Plexus Blockade
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Hermanns, Henning, Braun, Sebastian, Werdehausen, Robert, Werner, Andreas, Lipfert, Peter, and Stevens, Markus F.
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- 2007
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34. Uniform Distribution of Skin-Temperature Increase After Different Regional-Anesthesia Techniques of the Lower Extremity
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Werdehausen, Robert, Braun, Sebastian, Hermanns, Henning, Freynhagen, Rainer, Lipfert, Peter, and Stevens, Markus F.
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- 2007
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35. Increase in Skin Temperature After Spinal Anesthesia in Infants
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Jetzek-Zader, Martin, Hermanns, Henning, Freynhagen, Rainer, Lipfert, Peter, and Stevens, Markus F.
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- 2006
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36. Regeneration of baroafferents after implantation into different vessels
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Stevens, Markus F., Hermanns, Henning, Freynhagen, Rainer, Novotny, Gerd E. K., and Lipfert, Peter
- Published
- 2007
37. Face and construct validity of TU-Delft epidural simulator and the value of real-time visualization
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Zivkovic, Nenad (author), Van Samkar, Ganapathy (author), Hermanns, Henning (author), Lirk, Philipp (author), Hollmann, Markus W. (author), van den Dobbelsteen, J.J. (author), van Gerwen, D.J. (author), Stevens, Markus J. (author), Zivkovic, Nenad (author), Van Samkar, Ganapathy (author), Hermanns, Henning (author), Lirk, Philipp (author), Hollmann, Markus W. (author), van den Dobbelsteen, J.J. (author), van Gerwen, D.J. (author), and Stevens, Markus J. (author)
- Abstract
Background and objectives Learning epidural anesthesia traditionally involves bedside teaching. Visualization aids or a simulator can help in acquiring motor skills, increasing patient safety and steepening the learning curve. We evaluated the face and construct validity of the TU-Delft Epidural Simulator and the effect of needle visualization. Methods Sixty-eight anesthesiologists, anesthesia residents, and final-year medical students tested the epidural simulator. Participants performed six epidural simulations with and six without needle visualization. We tested face validity on a Likert scale questionnaire. We collected data with the simulator software (spinal taps, dura contacts, bone contacts, attempts, and time) and tested for correlation with the performer's experience (construct validity). A visualization aid was tested in a randomized crossover design. Results Face validity as rated by the participants was above average, with a mean of 3.7 (2.0-4.8) on a 5-point scale. Construct validity was indicated by significantly more spinal taps (0.4 [0-4) vs 0.07 [0-2], p=0.04) and more dura contacts (0.58 [0-6] vs 0.37 [0-3], p=0.002) by the inexperienced group compared with the expert group. The visualization aid improved performance by reducing the number of bone contacts and the number of attempts, and by decreasing the procedure time. Prior visualization training reduced the total procedure time from 279 s (69-574) to 180 s (53-605) (p=0.01) for the "blind" procedure. Conclusions The TU-Delft Epidural Simulator is a useful tool for teaching motor skills during epidural needle placement. Prior use of a visualization tool improves performance even without visual support during consequent simulations., Medical Instruments & Bio-Inspired Technology
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- 2019
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38. Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study
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Kirmeier, Eva, Eriksson, Lars I., Lewald, Heidrun, Jonsson Fagerlund, Malin, Hoeft, Andreas, Hollmann, Markus, Meistelman, Claude, Hunter, Jennifer M., Ulm, Kurt, Blobner, Manfred, Abad Gurumeta, Alfredo, Abernethy, Caroline, Abigail, Patrick, Achaibar, Kira, Adam, Emily, Afshari, Arash, Agudelo Montoya, M. Elizabeth, Akgün, Fatma Nur, Aletti, Gabriele, Alkış, Neslihan, Allan, Katie, Allan, Ashley, Allaouchiche, Bernard, Allcock, Clare, Almasy, Emoke, Amey, Isobel, Amigoni, Maria, Andersen, Elin, Andersson, Peder, Anipchenko, Natalya, Antunes, Pedro, Armstrong, Earlene, Aslam, Tayyba Naz, Aslin, Bjorn, Assunção, José Pedro, Ausserer, Julia, Avvai, Mary, Awad, Nahla, Ayas Montero, Begoña, Ayuso, Mercedes, Azevedo, Patricia, Badarau, Victoria, Badescu, Roxana, Baiardo Redaelli, Martina, Baird, Colin, Baird, Yolanda, Baker, Tim, Balaji, Packianathaswamy, Bălan, Cristina, Balandin, Alina, Balescu-Arion, Carmen, Baliuliene, Vilda, Baltasar Isabel, Jorge, Baluch, Saif Nasr, Bandrabur, Daniela, Bankewitz, Carla, Barber, Katrina, Barbera, Francesco, Barcraft-Barnes, Helena, Barletti, Valentina, Barnett, Gill, Baron, Kirsty, Barros, Ana, Barsan, Victoria, Bartlett, Pauline, Batistaki, Chrysanthi, Baumgarten, Georg, Baytas, Volkan, Beauchamp, Nigel, Becerra Cayetano, Isabel A., Bell, Stephanie, Bellandi, Mattia, Belletti, Alessandro, Belmonte Cuenca, Julio, Benitez-Cano, Adela, Beretta, Luigi, Berger, Marc, Bergmann, Nicole, Bergmark, Kristina, Bermudez Lopez, Maria, Bernotaite, Monika, Beurskens, Charlotte, Bidd, Heena, Bifulco, Francesca, Bignami, Elena, Bilic, Aleksandar, Bilskiene, Diana, Bischoff, Petra, Bishop, Luke, Bjonness, Therese, Blaylock, Hether, Blethyn, Kate, Blincoe, Thomas, Blokhin, Ivan, Blunt, Nadia, Boer, Christa, Bois, Grégory, Bonicolini, Eleonora, Booth, Joanna, Borecka-Kedzierska, Miroslawa, Borstnar, Katarina, Borys, Michał, Boselli, Emmanuel, Bouvet, Lionel, Bouwman, Arthur, Bowen, Leonora, Bowrey, Sarah, Boxall, Leigh, Božić, Teodora, Bradley, Tom, Branco, Teresa, Brazzi, Luca, Brazzoni, Marcella, Brear, Tracy, Brogly, Nicolas, Brohi, Farooq, Broms, Jacob, Bubliauskas, Andrius, Bucolo, Gea Erika, Buerkle, Hartmut, Buggy, Donal, Buhre, Wolfgang, Bukauskas, Tomas, Butturini, Francesco, Byttner, Anders, Cabrera Díaz, Itahísa, Calderon, Adriana, Calhau, Ricardo, Callejo, Angel, Cammu, Guy, Campesato, Manuela, Can, Özlem S, Candeias, Margarida, Cantor, Andreea, Carise, Elsa, Carmona, Cristina, Carreteiro, Joana, Carrieri, Cosima, Carter, Anna, Casal, Manuela, Casanova, Irene, Cascella, Marco, Casero, Luis M., Casiraghi, Guiseppina Maria, Castelo-Branco, Laila, Castro Arranz, Carlos, Cernea, Daniela Denisa, Cervantes, Jesoporiol, Chandler, Ben, Charnock, Robert, Chatzimicali, Aikaterini, Chinery, Elane, Chishti, Ahmed, Chondhury, Priyakam, Christie, Emily, Christodoudiles, George, Ciardo, Stefano, Cimpeanu, Luminata, Cindea, Iulia, Cinnella, Gilda, Clark, Sebastian, Clayton, Matthew, Cocu, Simona, Collyer, Thomas, Colvin, Carie, Cope, Sean, Copeta, Filomena, Copotoiu, Sanda-Maria, Correia de Barros, Filinto, Corso, Ruggero Massimo, Cortegiani, Andrea, Costa, Gabriela, Cowton, Amanda, Cox, Nicolas, Craig, James, Cricca, Valentina, Cronin, John, Cunha, Mariana, Cuomo, Arturo, Curley, Katherine, Czuczwar, Mirosław, Dabrowska, Domenika, Damster, Sabrine, Danguy des Déserts, Marc, Daniliuc, Aura, Danninger, Thomas, Darwish, Imad, Dascalu, Corina, Davies, Kirsty, Davies, Simon, De Boer, Hans, De Flaviis, Adelisa, De Selincourt, Gabrielle, Deana, Cristian, Debaene, Bertrand, Debreceni, Gabor, Dedhia, Jatin, Delgado Garcia, Isabel, Della Rocca, Giorgio, Delroy-Buelles, Llana, Desai, Tejal, Dhillon, Parveen, Di Giacinto, Ida, Di Mauro, Piero, Diaz Gomez, Tamara V., Dimitrovski, Aleksandar, Dinic, Vesna, Dîrzu, Dan-Sebastian, Divander, Mona Britt, Dolinar, Janez, Domingues, Susana, Doolan, James, Downes, Charlotte, Dragoescu, Nicoleta Alice, Droc, Gabriela, Dum, Elisabeth, Dumitrescu, Alexandra, Duncan, Louise, Dzurňáková, Paul, Eberl, Susanne, Edwards, Jayne, Edwards, Mark, Ekelund, Kim, Ekengren, Patrik, Elghouty, Eyad, Ellerkmann, Richard, Ellis, Helen, Elme, Andreas, Ernst, Thomas, Errando, Carlos Luis, Estenes, Simao, Ewaldsson, Callis, Farid, Nahla, Featherstone, James, Febres, Daniela, Fedorov, Sergey, Feggeler, Johanna, Feijten, Prisca, Fellmann, Tobias, Fernandez Candil, Juan, Fernandez Castineira, Ana, Fernández Castineira, Juan, Fernando, Aruna, Ferrando, Carlos, Ferreira, Leonia, Ferreira, Patrick, Feyling, Anders, Filipescu, Daniela, Fleischer, Andreas, Floris, Leda, Foerster, Urs, Fox, Benjamin, Franke, Uwe, Frasca, Denis, Frey, Christian, Frost, Victoria, Fullin, Giorgio, Fumagalli, Jacopo, Furneval, Julie, Fusari, Maurizio, Gallacher, Stuart, Galushka, Svetlana, Gambale, Giorgio, Gambino, Irene, Garcia-Perez, Maria Luisa, Garg, Sanjeev, Garlak, Justyna, Gavranovic, Zeljka, Gavrilov, Roman, Gaynor, Lames, Gecaj Gashi, Agreta, Georghiou, Maria, Gerjevic, Bozena, Gferer, Gudrun, Giarratano, Antonino, Gibson, Andy, Gievski, Vanja, Giles, Julian, Gillberg, Lars, Gilowska, Katarzyna, Gilsanz Rodriguez, Fernando, Gioia, Antonio, Giovannoni, Cecilia, Girotra, Vandana, Gkinas, Dimitrios, Gkiokas, George, Godoroja, Daniela, Goebel, Ulrich, Goel, Vandana, Gonzalez, Matilde, Goranovic, Tatjana, Gornik-Wlaszczuk, Ewa, Gosavi, Smita, Gottfridsson, Peter, Gottschalk, André, Granell, Manuel, Granstrom, Anna, Grassetto, Alberto, Greenwood, Anna, Grigoras, Ioana, Grintescu, Ioana, Gritsan, Alexey, Gritsan, Galina, Grynyuk, Andriy, Guadagnin, Giovanni Maria, Guarnieri, Marcello, Güçlü, Çiğdem, Guerrero Diez, Maria, Gunenc, Ferim, Günther, Ulf, Gupta, Pawan, Guttenthaler, Vera, Hack, Yvonne, Hafisayena, Ade, Hagau, Natalia, Haldar, Jagannath, Hales, Dawn, Hancı, Volkan, Hanna-Jumma, Sameer, Harazim, Hana, Harlet, Pierre, Harper, Daniel, Harris, Benjamin, Harvey, Orla, Hashimi, Medita, Hawkins, Lesley, Hayes, Conrad, Heaton, James, Heier, Tom, Helliwell, Laurence, Hemmes, Sabrine, Henderson, Kate, Hermanides, Jeroen, Hermanns, Henning, Herrera Hueso, Berta, Hestenes, Siv, Hettiarachchi, Roshane, Highgate, Judith, Hodgson, Keith, Hoelbling, Daniel, Holland, Jonathan, Horhota, Lucian, Hormis, Anil, Hribar, Renata, Hua, Alina, Humphreys, Sally, Humphries, Ryan, Humpliková, Simona, Hunt, Janez, Husnain, Ali, Hussein, Ahmed, Hyams, Benjamin, Iannuccelli, Fabrizio, Ilette, Katie, Ilyas, Carl, Inan, Turgay, India, Immaculada, Ionițăv, Victor, Irwin, Foo, Jain, Vipul, Janez, Benedikt, Jankovic, Radmilo, Jenkins, Sarah, Jenko, Matej, Jimenez, Raquel, Jiménez Gomez, Bárbara, Joachim, Sugganthi, Joelsson-Alm, Eva, John, John, Jonikaite, Lina, Jovic, Miomir, Jungwirth, Bettina, Junke, Etienne, Kabakov, Borys, Kadaoui, Salah-Din, Kanski, Andrzej, Karadag, Süheyla, Karbonskiene, Aurika, Karjagin, Juri, Kasnik, Darja, Katanolli, Fatos, Katsika, Eleni, Kaufmann, Kai, Keane, Helen, Kelly, Martin, Kent, Melanie, Keraitiene, Grazina, Khudhur, Ahmed, Khuenl-Brady, Karin, Kidd, Laurie, King, Siobhan, Kirchgäßner, Katharina, Klancir, Tino, Klucniks, Andris, Knotzer, Johann, Knowlden, Peter, Koers, Lena, Kompan, Janez, Koneti, Kiran K, Kooij, Fabian, Koolen, Eric, Koopman - van Gemert, Anna Wilhelmina Margaretha Maria, Kopp, Kristen, Korfiotis, Dimitrios, Korolkov, Oleg, Kosinová, Martina, Köstenberger, Markus, Kotzinger, Oskar, Kovačević, Marko, Kranke, Peter, Kranke, Eva, Kraus, Christiane, Kraus, Stephanie, Kubitzek, Christiane, Kucharski, Rafal, Kucukguclu, Semih, Kudrashou, Allaksandr, Kumar, Vinayak, Kummen, Live, Kunit, Cornelia, Kushakovsky, Vlad, Kuvaki, Bahar, Kuzmanovska, Biljana, Kyttari, Aikaterina, Landoni, Giovanni, Lau, Gary, Lazarev, Konstantin, Legett, Samantha, Legrottaglie, Anna Maria, Leonardi, Silvia, Leong, Maria, Lercher, Helene, Leuvrey, Matthieu, Leva, Brigitte, Levstek, Meta, Limb, James, Lindholm, Espen, Linton, Fiona, Liperi, Corradero, Lipski, Fabian, Lirk, Philipp, Lisi, Alberto, Lišková, Katarina, Lluch Oltra, Aitana, Loganathan, Vinothan, Lombardi, Stefania, Lopez, Eloisa, Lopez Rodríguez, Maria, Lorenzini, Laura, Lowicka, Malgorzata, Lugovoy, Alexander, Luippold, Madeleine, Lumb, Andrew, Macas, Andrius, Macgregor, Mark, Machado, Humberto, Maciariello, Maria, Madeira, Isabel, Maitan, Stefan, Majewski, Jacek, Maldini, Branka, Malewski, Georgia, Manfredini, Livia, Männer, Olja, Marchand, Bahareh, Marcu, Alexandra, Margalef, Jordi, Margarson, Michael, Marinheiro, Lucia, Markic, Ana, Markovic Bozic, Jasmina, Marrazzo, Francesco, Martin, Jane, Martin Ayuso, Maria, Martinez, Esteher, Martino, Enrico Antonio, Martinson, Victoria, Marusic-Gaser, Katarina, Mascarenhas, Catia, Mathis, Cindy, Matsota, Paraskevi, Mavrommati, Eleni, Mazul Sunko, Branka, McCourt, Killian, McGill, Neil, McKee, Raymond, Meço, Başak Ceyda, Meier, Sonja, Melbourne, Susan, Melbybråthen, Grethe, Meli, Andrea, Melia, Aiden, Melotti, Rita Maria, Menga, Maria Rosaria, Mercer, Pauline, Merotra, Susan, Mescolini, Silvia, Metterlein, Thomas, Michalov, Martin, Michlig, Sam, Midgley, Susan, Milić, Morena, Milojevic, Milan, Miñana, Amanda, Minto, Gary, Mirabella, Lucia, Mirea, Liliana, Mittelstädt, Ludger, Moeglen, Aude, Moise, Alida, Mokini, Zhirajr, Molin, Anna, Moltó, Luis, Monea, Maria Concetta, Montalto, Francesca, Montgomery, Jane, Montgomery, Claire, Montillo, Gerardo, Moore, Sally, Moore, Faye, Moreira, Zelia, Moreno, Tania, Moreno, Ricardo, Moret, Enrique, Moreton, Sarah, Morgan, Marianne, Moro Velasco, Concepción, Morri, Davide, Moull, Alice, Moura, Fernando, Mráz, Peter, Mrozek, Katarzyna, Mukhtar, Karim, Muniyappa, Sudeshkumar, Murray, Heather, Murthy, Burra VS, Mushambi, Mary, Nadolski, Maria, Nardelli, Pasquale, Nardin, Giordano, Navarro Pérez, Rosalía, Naveiro, Andrea, Negri, Manuela, Nesek Adam, Visnja, Neskovic, Vojislava, Neuwersch, Stefan, Neves, Miriam, Nguyen, Bavinh, Ní Eochagáin, Aisling, Nicholas, Caroline, Nightingale, Jeremy, Norrie, Kylie, Novak-Jankovic, Vesna, Novakova, Andrea, Novillo, Marta, Numan, Sandra, Oduro-Dominah, Louise, Oldner, Anders, Oliveira, Isabel, Ologoiu, Daniela, Oloktsidou, Irini, O'Reilly, Rosalind, Orlando, Alessandro, Ovezov, Alexey, Ozbilgin, Sule, Paal, Peter, Padin Barreiro, Lidia, Palugniok, Ryszard, Papaioannou, Alexandra, Papapostolou, Konstantinos, Paranthaman, Prabhakar, Pardey Bracho, Gilda, Parente, Suzana, Parfeni, Alexandru, Pasin, Laura, Passey, Samuel, Pastor, Ernesto, Patch, Sarah, Patil, Andan, Paunescu, Marilena-Alina, Pehboeck, Daniel, Pereira, Manuela, Pereira, Carla, Perez Caballero, Paula, Pérez García, Aníbal, Pérez Soto, Antonia, Perez Tejero, Gisela, Perez-Cerda, Francisco, Pesenti, Antonio, Petta, Rocco, Philippe, Simon, Pickering, David, Pico Veloso, Jandro, Pina, Pedro, Pinho-Oliveira, Vítor, Pinol, Santiago, Pinto, Rita, Pistidda, Laura, Pitterle, Manuela, Piwowarczyk, Paweł, Plotnikova, Olga, Pohl, Holger, Poldermann, Jorinde, Polkovicová, Lucia, Pompei, Livia, Popescu, Mihai, Popović, Radmila, Pota, Vincenzo, Potocnik, Miriam, Potręć, Beata, Potter, Alison, Pramod, Nalwaya, Prchalova, Martina, Preckel, Benedikt, Pugh, Richard, Pulletz, Mark, Radoeshki, Aleksandar, Rafi, Amir, Ragazzi, Riccardo, Raineri Santi, Maurizio, Rajamanickam, Tamiselvan, Rajput, Zahra, Ramachandran, Rajeskar, Ramasamy, Radhika, Ramessur, Suneil, Rao, Roshan, Rasmussen, Anders, Rato, André, Razaque, Usman, Real Navacerrada, M. Isabel, Reavley, Caroline, Reid, James, Reschreiter, Henrik, Rial, Erick, Ribas Carrasco, Patricia, Ribeiro, Sandy, Rich, Nathalie, Richardson, Lydia, Rimaitis, Kestutis, Rimaitis, Marius, Ringvold, Else-Marie, Ripke, Fabian, Ristescu, Irina, Ritchie, Keith, Ródenas, Frederic, Rodrigues, Patrícia, Rogers, Emma, Rogerson, David, Romagnoli, Stefano, Romero, Esther, Rondovic, Goran, Rose, Bernd Oliver, Roth, Winfried, Rotter, Marie-Therese, Rousseau, Guy, Rudjord, Anders, Rueffert, Henrik, Rundgren, Malin, Rupprecht, Korbinian, Rushton, Andrew, Russotto, Vincenzo, Rypulak, Elżbieta, Ryszka, Maciej, Sà, Jacinta, Sà Couto, Paula, Saby, Sandrine, Sagic, Jelena, Saleh, Omar, Sales, Gabriele, Sánchez Sánchez, Yván, Sanghera, Sumayer, Şanli Karip, Ceren, Santiveri Papiol, Francisco Javier, Santos, Sofia, Sarno, Stephen, Saul, Daniel, Saunders, David, Savic, Nenad, Scalco, Loïc, Scanlon, Deborah, Schaller, Stefan, Schax, Christoph, Scheffer, Gert Jan, Schening, Anna, Schiavone, Vincenzo, Schmidt-Ehrenberg, Florian, Schmidt-Mutter, Catherine, Schönberg, Christina, Schopflin, Christian, Schreiber, Jan-Uwe, Schultz, Marcus, Schurig, Marlen, Scott, Carmen, Sebestian, Siby, Sehgal, Selena, Sem, Victoria, Semenas, Egidijus, Serafini, Elena, Serchan, Pashalitsa, Shields, Martin, Shobha, Ramakrishnan, Shosholcheva, Mirjana, Siamansour, Tanja, Siddaiah, Narendra, Siddiqi, Khalid, Sinclair, Rhona, Singh, Permendra, Singh, Rajendra, Sinha, Aneeta, Sinha, Ashok, Skinner, Amanda, Smee, Elizabeth, Smekalova, Olga, Smith, Neil, Smith, Thomas, Smitz, Carine, Smole, Daniel, Sojčić, Nataša, Soler Pedrola, Maria, Somanath, Sameer, Sonksen, Julian, Sorella, Maria Christina, Sörmus, Alar, Soro, Marina, Soto, Carmen, Spada, Anna, Spadaro, Savino, Spaeth, Johannes, Sparr, Harald, Spielmann, Annika, Spindler-Vesel, Alenka, Stamelos, Matthaios, Stancombe L, Liucia, Stanculescu, Andreea, Standl, Thomas, Standley, Tom, Stanek, Ondrej, Stanisavljević, Snežana, Starczewska, Malgorzata, Stäuble, Christiane, Steen, Julie, Stefan, Oana Maria, Stell, Elizabeth, Stera, Caterina, Stevens, Markus, Stoerckel, Marlène, Stošić, Biljana, Stourac, Petr, Stroumpoulis, Konstantinos, Struck, Rafael, Suarez de la Rica, Alejandro, Sultanpori, Altaf, Sundara Rajan, Rajinikanth, Suying, Ong, Svensen, Christer, Swan, Louise, Syrogianni, Paulina, Sysiak, Justyna, Szederjesi, Janos, Taddei, Stefania, Tan Hao, Ern, Tanou, Virginia, Tarabová, Katarina, Tardaguila Sancho, Paula, Tarroso, Maria, Tartaglione, Marco, Taylor, Emma, Tbaily, Lee, Telford, Richard, Terenzoni, Massimo, Theodoraki, Kassiani, Thornley, Helen, Tiganiuc, Liviu, Toim, Hardo, Tomescu, Dana, Tommasino, Concezione, Toni, Jessica, Toninelli, Arturo, Toretti, Ilaria, Townley, Stephen, Trepenaitis, Darius, Trethowan, Brian, Tsaousi, Georgia, Tsiftsi, Aikaterini, Tudor, Adrada, Turan, Güldem, Turhan, Sanem Çakar, Unic-Stojanovic, Dragana, Unterbuchner, Christoph, Unzueta, Carmen, Uranjek, Jasna, Ursic, Tomaz, Vaida, Simona, Valldeperas Ferrer, Silvia, Valldeperas Hernandez, Maria Inmaculada, Valsamidis, Dimitri, Van Beek, Rienk, Van dasselaer, Nick, Van Der Beek, Tim, Van Duivenvoorde, Yoni, Van Klei, Wilton A., Van Poorter, Frans, Van Zaane, Bas, Van Zundert, Tom, Van Zyl, Rebekka, Vargas Munoz, Ana Milena, Varsani, Nimu, Vasconcelos, Pedro, Vassilakis, Georgios, Vecchiatini, Tommaso, Vecera, Lubomir, Vercauteren, Marcel, Verdouw, Bas, Verheyen, Veerle, Verri, Marco, Vicari Sottosanti, Luigi Giancarlo, Vico, Manuel, Vidal Mitjans, Patricia, Vilardi, Anna, Vissicchio, Daniela, Vitale, Giovanni, Vitković, Bibiana, Vizcaychipi, Marcela Paola, Voicu, Alexandra, Voje, Minca, Volfová, Ivana, Volta, Carlo Alberto, Von Lutterotti, Theresa, von Tiesenhausen, Anna, Vrecic-Slabe, Simona, Vukcevic, Dejan, Vukovic, Rade, Vullo, P. 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Elizabeth, Akgün, Fatma Nur, Aletti, Gabriele, Alkış, Neslihan, Allan, Katie, Allan, Ashley, Allaouchiche, Bernard, Allcock, Clare, Almasy, Emoke, Amey, Isobel, Amigoni, Maria, Andersen, Elin, Andersson, Peder, Anipchenko, Natalya, Antunes, Pedro, Armstrong, Earlene, Aslam, Tayyba Naz, Aslin, Bjorn, Assunção, José Pedro, Ausserer, Julia, Avvai, Mary, Awad, Nahla, Ayas Montero, Begoña, Ayuso, Mercedes, Azevedo, Patricia, Badarau, Victoria, Badescu, Roxana, Baiardo Redaelli, Martina, Baird, Colin, Baird, Yolanda, Baker, Tim, Balaji, Packianathaswamy, Bălan, Cristina, Balandin, Alina, Balescu-Arion, Carmen, Baliuliene, Vilda, Baltasar Isabel, Jorge, Baluch, Saif Nasr, Bandrabur, Daniela, Bankewitz, Carla, Barber, Katrina, Barbera, Francesco, Barcraft-Barnes, Helena, Barletti, Valentina, Barnett, Gill, Baron, Kirsty, Barros, Ana, Barsan, Victoria, Bartlett, Pauline, Batistaki, Chrysanthi, Baumgarten, Georg, Baytas, Volkan, Beauchamp, Nigel, Becerra Cayetano, Isabel A., Bell, Stephanie, 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Ricardo, Callejo, Angel, Cammu, Guy, Campesato, Manuela, Can, Özlem S, Candeias, Margarida, Cantor, Andreea, Carise, Elsa, Carmona, Cristina, Carreteiro, Joana, Carrieri, Cosima, Carter, Anna, Casal, Manuela, Casanova, Irene, Cascella, Marco, Casero, Luis M., Casiraghi, Guiseppina Maria, Castelo-Branco, Laila, Castro Arranz, Carlos, Cernea, Daniela Denisa, Cervantes, Jesoporiol, Chandler, Ben, Charnock, Robert, Chatzimicali, Aikaterini, Chinery, Elane, Chishti, Ahmed, Chondhury, Priyakam, Christie, Emily, Christodoudiles, George, Ciardo, Stefano, Cimpeanu, Luminata, Cindea, Iulia, Cinnella, Gilda, Clark, Sebastian, Clayton, Matthew, Cocu, Simona, Collyer, Thomas, Colvin, Carie, Cope, Sean, Copeta, Filomena, Copotoiu, Sanda-Maria, Correia de Barros, Filinto, Corso, Ruggero Massimo, Cortegiani, Andrea, Costa, Gabriela, Cowton, Amanda, Cox, Nicolas, Craig, James, Cricca, Valentina, Cronin, John, Cunha, Mariana, Cuomo, Arturo, Curley, Katherine, Czuczwar, Mirosław, Dabrowska, Domenika, Damster, Sabrine, Danguy des Déserts, Marc, Daniliuc, Aura, Danninger, Thomas, Darwish, Imad, Dascalu, Corina, Davies, Kirsty, Davies, Simon, De Boer, Hans, De Flaviis, Adelisa, De Selincourt, Gabrielle, Deana, Cristian, Debaene, Bertrand, Debreceni, Gabor, Dedhia, Jatin, Delgado Garcia, Isabel, Della Rocca, Giorgio, Delroy-Buelles, Llana, Desai, Tejal, Dhillon, Parveen, Di Giacinto, Ida, Di Mauro, Piero, Diaz Gomez, Tamara V., Dimitrovski, Aleksandar, Dinic, Vesna, Dîrzu, Dan-Sebastian, Divander, Mona Britt, Dolinar, Janez, Domingues, Susana, Doolan, James, Downes, Charlotte, Dragoescu, Nicoleta Alice, Droc, Gabriela, Dum, Elisabeth, Dumitrescu, Alexandra, Duncan, Louise, Dzurňáková, Paul, Eberl, Susanne, Edwards, Jayne, Edwards, Mark, Ekelund, Kim, Ekengren, Patrik, Elghouty, Eyad, Ellerkmann, Richard, Ellis, Helen, Elme, Andreas, Ernst, Thomas, Errando, Carlos Luis, Estenes, Simao, Ewaldsson, Callis, Farid, Nahla, Featherstone, James, Febres, Daniela, Fedorov, Sergey, Feggeler, Johanna, Feijten, Prisca, Fellmann, Tobias, Fernandez Candil, Juan, Fernandez Castineira, Ana, Fernández Castineira, Juan, Fernando, Aruna, Ferrando, Carlos, Ferreira, Leonia, Ferreira, Patrick, Feyling, Anders, Filipescu, Daniela, Fleischer, Andreas, Floris, Leda, Foerster, Urs, Fox, Benjamin, Franke, Uwe, Frasca, Denis, Frey, Christian, Frost, Victoria, Fullin, Giorgio, Fumagalli, Jacopo, Furneval, Julie, Fusari, Maurizio, Gallacher, Stuart, Galushka, Svetlana, Gambale, Giorgio, Gambino, Irene, Garcia-Perez, Maria Luisa, Garg, Sanjeev, Garlak, Justyna, Gavranovic, Zeljka, Gavrilov, Roman, Gaynor, Lames, Gecaj Gashi, Agreta, Georghiou, Maria, Gerjevic, Bozena, Gferer, Gudrun, Giarratano, Antonino, Gibson, Andy, Gievski, Vanja, Giles, Julian, Gillberg, Lars, Gilowska, Katarzyna, Gilsanz Rodriguez, Fernando, Gioia, Antonio, Giovannoni, Cecilia, Girotra, Vandana, Gkinas, Dimitrios, Gkiokas, George, Godoroja, Daniela, Goebel, Ulrich, Goel, Vandana, Gonzalez, Matilde, Goranovic, Tatjana, Gornik-Wlaszczuk, Ewa, Gosavi, Smita, Gottfridsson, Peter, Gottschalk, André, Granell, Manuel, Granstrom, Anna, Grassetto, Alberto, Greenwood, Anna, Grigoras, Ioana, Grintescu, Ioana, Gritsan, Alexey, Gritsan, Galina, Grynyuk, Andriy, Guadagnin, Giovanni Maria, Guarnieri, Marcello, Güçlü, Çiğdem, Guerrero Diez, Maria, Gunenc, Ferim, Günther, Ulf, Gupta, Pawan, Guttenthaler, Vera, Hack, Yvonne, Hafisayena, Ade, Hagau, Natalia, Haldar, Jagannath, Hales, Dawn, Hancı, Volkan, Hanna-Jumma, Sameer, Harazim, Hana, Harlet, Pierre, Harper, Daniel, Harris, Benjamin, Harvey, Orla, Hashimi, Medita, Hawkins, Lesley, Hayes, Conrad, Heaton, James, Heier, Tom, Helliwell, Laurence, Hemmes, Sabrine, Henderson, Kate, Hermanides, Jeroen, Hermanns, Henning, Herrera Hueso, Berta, Hestenes, Siv, Hettiarachchi, Roshane, Highgate, Judith, Hodgson, Keith, Hoelbling, Daniel, Holland, Jonathan, Horhota, Lucian, Hormis, Anil, Hribar, Renata, Hua, Alina, Humphreys, Sally, Humphries, Ryan, Humpliková, Simona, Hunt, Janez, Husnain, Ali, Hussein, Ahmed, Hyams, Benjamin, Iannuccelli, Fabrizio, Ilette, Katie, Ilyas, Carl, Inan, Turgay, India, Immaculada, Ionițăv, Victor, Irwin, Foo, Jain, Vipul, Janez, Benedikt, Jankovic, Radmilo, Jenkins, Sarah, Jenko, Matej, Jimenez, Raquel, Jiménez Gomez, Bárbara, Joachim, Sugganthi, Joelsson-Alm, Eva, John, John, Jonikaite, Lina, Jovic, Miomir, Jungwirth, Bettina, Junke, Etienne, Kabakov, Borys, Kadaoui, Salah-Din, Kanski, Andrzej, Karadag, Süheyla, Karbonskiene, Aurika, Karjagin, Juri, Kasnik, Darja, Katanolli, Fatos, Katsika, Eleni, Kaufmann, Kai, Keane, Helen, Kelly, Martin, Kent, Melanie, Keraitiene, Grazina, Khudhur, Ahmed, Khuenl-Brady, Karin, Kidd, Laurie, King, Siobhan, Kirchgäßner, Katharina, Klancir, Tino, Klucniks, Andris, Knotzer, Johann, Knowlden, Peter, Koers, Lena, Kompan, Janez, Koneti, Kiran K, Kooij, Fabian, Koolen, Eric, Koopman - van Gemert, Anna Wilhelmina Margaretha Maria, Kopp, Kristen, Korfiotis, Dimitrios, Korolkov, Oleg, Kosinová, Martina, Köstenberger, Markus, Kotzinger, Oskar, Kovačević, Marko, Kranke, Peter, Kranke, Eva, Kraus, Christiane, Kraus, Stephanie, Kubitzek, Christiane, Kucharski, Rafal, Kucukguclu, Semih, Kudrashou, Allaksandr, Kumar, Vinayak, Kummen, Live, Kunit, Cornelia, Kushakovsky, Vlad, Kuvaki, Bahar, Kuzmanovska, Biljana, Kyttari, Aikaterina, Landoni, Giovanni, Lau, Gary, Lazarev, Konstantin, Legett, Samantha, Legrottaglie, Anna Maria, Leonardi, Silvia, Leong, Maria, Lercher, Helene, Leuvrey, Matthieu, Leva, Brigitte, Levstek, Meta, Limb, James, Lindholm, Espen, Linton, Fiona, Liperi, Corradero, Lipski, Fabian, Lirk, Philipp, Lisi, Alberto, Lišková, Katarina, Lluch Oltra, Aitana, Loganathan, Vinothan, Lombardi, Stefania, Lopez, Eloisa, Lopez Rodríguez, Maria, Lorenzini, Laura, Lowicka, Malgorzata, Lugovoy, Alexander, Luippold, Madeleine, Lumb, Andrew, Macas, Andrius, Macgregor, Mark, Machado, Humberto, Maciariello, Maria, Madeira, Isabel, Maitan, Stefan, Majewski, Jacek, Maldini, Branka, Malewski, Georgia, Manfredini, Livia, Männer, Olja, Marchand, Bahareh, Marcu, Alexandra, Margalef, Jordi, Margarson, Michael, Marinheiro, Lucia, Markic, Ana, Markovic Bozic, Jasmina, Marrazzo, Francesco, Martin, Jane, Martin Ayuso, Maria, Martinez, Esteher, Martino, Enrico Antonio, Martinson, Victoria, Marusic-Gaser, Katarina, Mascarenhas, Catia, Mathis, Cindy, Matsota, Paraskevi, Mavrommati, Eleni, Mazul Sunko, Branka, McCourt, Killian, McGill, Neil, McKee, Raymond, Meço, Başak Ceyda, Meier, Sonja, Melbourne, Susan, Melbybråthen, Grethe, Meli, Andrea, Melia, Aiden, Melotti, Rita Maria, Menga, Maria Rosaria, Mercer, Pauline, Merotra, Susan, Mescolini, Silvia, Metterlein, Thomas, Michalov, Martin, Michlig, Sam, Midgley, Susan, Milić, Morena, Milojevic, Milan, Miñana, Amanda, Minto, Gary, Mirabella, Lucia, Mirea, Liliana, Mittelstädt, Ludger, Moeglen, Aude, Moise, Alida, Mokini, Zhirajr, Molin, Anna, Moltó, Luis, Monea, Maria Concetta, Montalto, Francesca, Montgomery, Jane, Montgomery, Claire, Montillo, Gerardo, Moore, Sally, Moore, Faye, Moreira, Zelia, Moreno, Tania, Moreno, Ricardo, Moret, Enrique, Moreton, Sarah, Morgan, Marianne, Moro Velasco, Concepción, Morri, Davide, Moull, Alice, Moura, Fernando, Mráz, Peter, Mrozek, Katarzyna, Mukhtar, Karim, Muniyappa, Sudeshkumar, Murray, Heather, Murthy, Burra VS, Mushambi, Mary, Nadolski, Maria, Nardelli, Pasquale, Nardin, Giordano, Navarro Pérez, Rosalía, Naveiro, Andrea, Negri, Manuela, Nesek Adam, Visnja, Neskovic, Vojislava, Neuwersch, Stefan, Neves, Miriam, Nguyen, Bavinh, Ní Eochagáin, Aisling, Nicholas, Caroline, Nightingale, Jeremy, Norrie, Kylie, Novak-Jankovic, Vesna, Novakova, Andrea, Novillo, Marta, Numan, Sandra, Oduro-Dominah, Louise, Oldner, Anders, Oliveira, Isabel, Ologoiu, Daniela, Oloktsidou, Irini, O'Reilly, Rosalind, Orlando, Alessandro, Ovezov, Alexey, Ozbilgin, Sule, Paal, Peter, Padin Barreiro, Lidia, Palugniok, Ryszard, Papaioannou, Alexandra, Papapostolou, Konstantinos, Paranthaman, Prabhakar, Pardey Bracho, Gilda, Parente, Suzana, Parfeni, Alexandru, Pasin, Laura, Passey, Samuel, Pastor, Ernesto, Patch, Sarah, Patil, Andan, Paunescu, Marilena-Alina, Pehboeck, Daniel, Pereira, Manuela, Pereira, Carla, Perez Caballero, Paula, Pérez García, Aníbal, Pérez Soto, Antonia, Perez Tejero, Gisela, Perez-Cerda, Francisco, Pesenti, Antonio, Petta, Rocco, Philippe, Simon, Pickering, David, Pico Veloso, Jandro, Pina, Pedro, Pinho-Oliveira, Vítor, Pinol, Santiago, Pinto, Rita, Pistidda, Laura, Pitterle, Manuela, Piwowarczyk, Paweł, Plotnikova, Olga, Pohl, Holger, Poldermann, Jorinde, Polkovicová, Lucia, Pompei, Livia, Popescu, Mihai, Popović, Radmila, Pota, Vincenzo, Potocnik, Miriam, Potręć, Beata, Potter, Alison, Pramod, Nalwaya, Prchalova, Martina, Preckel, Benedikt, Pugh, Richard, Pulletz, Mark, Radoeshki, Aleksandar, Rafi, Amir, Ragazzi, Riccardo, Raineri Santi, Maurizio, Rajamanickam, Tamiselvan, Rajput, Zahra, Ramachandran, Rajeskar, Ramasamy, Radhika, Ramessur, Suneil, Rao, Roshan, Rasmussen, Anders, Rato, André, Razaque, Usman, Real Navacerrada, M. Isabel, Reavley, Caroline, Reid, James, Reschreiter, Henrik, Rial, Erick, Ribas Carrasco, Patricia, Ribeiro, Sandy, Rich, Nathalie, Richardson, Lydia, Rimaitis, Kestutis, Rimaitis, Marius, Ringvold, Else-Marie, Ripke, Fabian, Ristescu, Irina, Ritchie, Keith, Ródenas, Frederic, Rodrigues, Patrícia, Rogers, Emma, Rogerson, David, Romagnoli, Stefano, Romero, Esther, Rondovic, Goran, Rose, Bernd Oliver, Roth, Winfried, Rotter, Marie-Therese, Rousseau, Guy, Rudjord, Anders, Rueffert, Henrik, Rundgren, Malin, Rupprecht, Korbinian, Rushton, Andrew, Russotto, Vincenzo, Rypulak, Elżbieta, Ryszka, Maciej, Sà, Jacinta, Sà Couto, Paula, Saby, Sandrine, Sagic, Jelena, Saleh, Omar, Sales, Gabriele, Sánchez Sánchez, Yván, Sanghera, Sumayer, Şanli Karip, Ceren, Santiveri Papiol, Francisco Javier, Santos, Sofia, Sarno, Stephen, Saul, Daniel, Saunders, David, Savic, Nenad, Scalco, Loïc, Scanlon, Deborah, Schaller, Stefan, Schax, Christoph, Scheffer, Gert Jan, Schening, Anna, Schiavone, Vincenzo, Schmidt-Ehrenberg, Florian, Schmidt-Mutter, Catherine, Schönberg, Christina, Schopflin, Christian, Schreiber, Jan-Uwe, Schultz, Marcus, Schurig, Marlen, Scott, Carmen, Sebestian, Siby, Sehgal, Selena, Sem, Victoria, Semenas, Egidijus, Serafini, Elena, Serchan, Pashalitsa, Shields, Martin, Shobha, Ramakrishnan, Shosholcheva, Mirjana, Siamansour, Tanja, Siddaiah, Narendra, Siddiqi, Khalid, Sinclair, Rhona, Singh, Permendra, Singh, Rajendra, Sinha, Aneeta, Sinha, Ashok, Skinner, Amanda, Smee, Elizabeth, Smekalova, Olga, Smith, Neil, Smith, Thomas, Smitz, Carine, Smole, Daniel, Sojčić, Nataša, Soler Pedrola, Maria, Somanath, Sameer, Sonksen, Julian, Sorella, Maria Christina, Sörmus, Alar, Soro, Marina, Soto, Carmen, Spada, Anna, Spadaro, Savino, Spaeth, Johannes, Sparr, Harald, Spielmann, Annika, Spindler-Vesel, Alenka, Stamelos, Matthaios, Stancombe L, Liucia, Stanculescu, Andreea, Standl, Thomas, Standley, Tom, Stanek, Ondrej, Stanisavljević, Snežana, Starczewska, Malgorzata, Stäuble, Christiane, Steen, Julie, Stefan, Oana Maria, Stell, Elizabeth, Stera, Caterina, Stevens, Markus, Stoerckel, Marlène, Stošić, Biljana, Stourac, Petr, Stroumpoulis, Konstantinos, Struck, Rafael, Suarez de la Rica, Alejandro, Sultanpori, Altaf, Sundara Rajan, Rajinikanth, Suying, Ong, Svensen, Christer, Swan, Louise, Syrogianni, Paulina, Sysiak, Justyna, Szederjesi, Janos, Taddei, Stefania, Tan Hao, Ern, Tanou, Virginia, Tarabová, Katarina, Tardaguila Sancho, Paula, Tarroso, Maria, Tartaglione, Marco, Taylor, Emma, Tbaily, Lee, Telford, Richard, Terenzoni, Massimo, Theodoraki, Kassiani, Thornley, Helen, Tiganiuc, Liviu, Toim, Hardo, Tomescu, Dana, Tommasino, Concezione, Toni, Jessica, Toninelli, Arturo, Toretti, Ilaria, Townley, Stephen, Trepenaitis, Darius, Trethowan, Brian, Tsaousi, Georgia, Tsiftsi, Aikaterini, Tudor, Adrada, Turan, Güldem, Turhan, Sanem Çakar, Unic-Stojanovic, Dragana, Unterbuchner, Christoph, Unzueta, Carmen, Uranjek, Jasna, Ursic, Tomaz, Vaida, Simona, Valldeperas Ferrer, Silvia, Valldeperas Hernandez, Maria Inmaculada, Valsamidis, Dimitri, Van Beek, Rienk, Van dasselaer, Nick, Van Der Beek, Tim, Van Duivenvoorde, Yoni, Van Klei, Wilton A., Van Poorter, Frans, Van Zaane, Bas, Van Zundert, Tom, Van Zyl, Rebekka, Vargas Munoz, Ana Milena, Varsani, Nimu, Vasconcelos, Pedro, Vassilakis, Georgios, Vecchiatini, Tommaso, Vecera, Lubomir, Vercauteren, Marcel, Verdouw, Bas, Verheyen, Veerle, Verri, Marco, Vicari Sottosanti, Luigi Giancarlo, Vico, Manuel, Vidal Mitjans, Patricia, Vilardi, Anna, Vissicchio, Daniela, Vitale, Giovanni, Vitković, Bibiana, Vizcaychipi, Marcela Paola, Voicu, Alexandra, Voje, Minca, Volfová, Ivana, Volta, Carlo Alberto, Von Lutterotti, Theresa, von Tiesenhausen, Anna, Vrecic-Slabe, Simona, Vukcevic, Dejan, Vukovic, Rade, Vullo, P. Agostina, Wade, Andrew, Wallberg, Hanna, Wallden, Jakob, Wallner, Johann, Walther Sturesson, Louise, Watson, Davina, Weber, Stefan, Wegiel Leskiewiq, Anna, Weller, Debbie, Wensing, Carine, Werkmann, Markus, Westberg, Henrik, Wikström, Erik, Williams, Benedict, Wilson, Robin, Wirth, Steffen, Wittmann, Maria, Wood, Laura, Wright, Stella, Zachoval, Christian, Zambon, Massimo, Zampieri, Silvia, Zampone, Salvatore, Zangrillo, Alberto, Zani, Gianluca, Zavackiene, Asta, Zieglerder, Raphael, Zonneveldt, Harry, Zsisku, Lajos, Zucker, Tom-Philipp, Żukowski, Maciej, Zuleika, Mehrun, and Zupanĕiĕ, Darja
- Published
- 2019
39. MiR-34a is differentially expressed in dorsal root ganglia in a rat model of chronic neuropathic pain
- Author
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Brandenburger, Timo, primary, Johannsen, Laura, additional, Prassek, Victoria, additional, Kuebart, Anne, additional, Raile, Jürgen, additional, Wohlfromm, Sebastian, additional, Köhrer, Karl, additional, Huhn, Ragnar, additional, Hollmann, Markus W, additional, and Hermanns, Henning, additional
- Published
- 2019
- Full Text
- View/download PDF
40. Reply
- Author
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Hermanns, Henning, primary and Kaya, Abdullah, additional
- Published
- 2019
- Full Text
- View/download PDF
41. Two Cases of Endocarditis After MitraClip Procedure Necessitating Surgical Mitral Valve Replacement
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Hermanns, Henning, primary, Wiegerinck, Esther M.A., additional, Lagrand, Wim K., additional, Baan, Jan, additional, Cocchieri, Riccardo, additional, and Kaya, Abdullah, additional
- Published
- 2019
- Full Text
- View/download PDF
42. Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study
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Kirmeier, Eva, primary, Eriksson, Lars I, additional, Lewald, Heidrun, additional, Jonsson Fagerlund, Malin, additional, Hoeft, Andreas, additional, Hollmann, Markus, additional, Meistelman, Claude, additional, Hunter, Jennifer M, additional, Ulm, Kurt, additional, Blobner, Manfred, additional, Abad Gurumeta, Alfredo, additional, Abernethy, Caroline, additional, Abigail, Patrick, additional, Achaibar, Kira, additional, Adam, Emily, additional, Afshari, Arash, additional, Agudelo Montoya, M. Elizabeth, additional, Akgün, Fatma Nur, additional, Aletti, Gabriele, additional, Alkış, Neslihan, additional, Allan, Katie, additional, Allan, Ashley, additional, Allaouchiche, Bernard, additional, Allcock, Clare, additional, Almasy, Emoke, additional, Amey, Isobel, additional, Amigoni, Maria, additional, Andersen, Elin, additional, Andersson, Peder, additional, Anipchenko, Natalya, additional, Antunes, Pedro, additional, Armstrong, Earlene, additional, Aslam, Tayyba Naz, additional, Aslin, Bjorn, additional, Assunção, José Pedro, additional, Ausserer, Julia, additional, Avvai, Mary, additional, Awad, Nahla, additional, Ayas Montero, Begoña, additional, Ayuso, Mercedes, additional, Azevedo, Patricia, additional, Badarau, Victoria, additional, Badescu, Roxana, additional, Baiardo Redaelli, Martina, additional, Baird, Colin, additional, Baird, Yolanda, additional, Baker, Tim, additional, Balaji, Packianathaswamy, additional, Bălan, Cristina, additional, Balandin, Alina, additional, Balescu-Arion, Carmen, additional, Baliuliene, Vilda, additional, Baltasar Isabel, Jorge, additional, Baluch, Saif Nasr, additional, Bandrabur, Daniela, additional, Bankewitz, Carla, additional, Barber, Katrina, additional, Barbera, Francesco, additional, Barcraft-Barnes, Helena, additional, Barletti, Valentina, additional, Barnett, Gill, additional, Baron, Kirsty, additional, Barros, Ana, additional, Barsan, Victoria, additional, Bartlett, Pauline, additional, Batistaki, Chrysanthi, additional, Baumgarten, Georg, additional, Baytas, Volkan, additional, Beauchamp, Nigel, additional, Becerra Cayetano, Isabel A., additional, Bell, Stephanie, additional, Bellandi, Mattia, additional, Belletti, Alessandro, additional, Belmonte Cuenca, Julio, additional, Benitez-Cano, Adela, additional, Beretta, Luigi, additional, Berger, Marc, additional, Bergmann, Nicole, additional, Bergmark, Kristina, additional, Bermudez Lopez, Maria, additional, Bernotaite, Monika, additional, Beurskens, Charlotte, additional, Bidd, Heena, additional, Bifulco, Francesca, additional, Bignami, Elena, additional, Bilic, Aleksandar, additional, Bilskiene, Diana, additional, Bischoff, Petra, additional, Bishop, Luke, additional, Bjonness, Therese, additional, Blaylock, Hether, additional, Blethyn, Kate, additional, Blincoe, Thomas, additional, Blokhin, Ivan, additional, Blunt, Nadia, additional, Boer, Christa, additional, Bois, Grégory, additional, Bonicolini, Eleonora, additional, Booth, Joanna, additional, Borecka-Kedzierska, Miroslawa, additional, Borstnar, Katarina, additional, Borys, Michał, additional, Boselli, Emmanuel, additional, Bouvet, Lionel, additional, Bouwman, Arthur, additional, Bowen, Leonora, additional, Bowrey, Sarah, additional, Boxall, Leigh, additional, Božić, Teodora, additional, Bradley, Tom, additional, Branco, Teresa, additional, Brazzi, Luca, additional, Brazzoni, Marcella, additional, Brear, Tracy, additional, Brogly, Nicolas, additional, Brohi, Farooq, additional, Broms, Jacob, additional, Bubliauskas, Andrius, additional, Bucolo, Gea Erika, additional, Buerkle, Hartmut, additional, Buggy, Donal, additional, Buhre, Wolfgang, additional, Bukauskas, Tomas, additional, Butturini, Francesco, additional, Byttner, Anders, additional, Cabrera Díaz, Itahísa, additional, Calderon, Adriana, additional, Calhau, Ricardo, additional, Callejo, Angel, additional, Cammu, Guy, additional, Campesato, Manuela, additional, Can, Özlem S, additional, Candeias, Margarida, additional, Cantor, Andreea, additional, Carise, Elsa, additional, Carmona, Cristina, additional, Carreteiro, Joana, additional, Carrieri, Cosima, additional, Carter, Anna, additional, Casal, Manuela, additional, Casanova, Irene, additional, Cascella, Marco, additional, Casero, Luis M., additional, Casiraghi, Guiseppina Maria, additional, Castelo-Branco, Laila, additional, Castro Arranz, Carlos, additional, Cernea, Daniela Denisa, additional, Cervantes, Jesoporiol, additional, Chandler, Ben, additional, Charnock, Robert, additional, Chatzimicali, Aikaterini, additional, Chinery, Elane, additional, Chishti, Ahmed, additional, Chondhury, Priyakam, additional, Christie, Emily, additional, Christodoudiles, George, additional, Ciardo, Stefano, additional, Cimpeanu, Luminata, additional, Cindea, Iulia, additional, Cinnella, Gilda, additional, Clark, Sebastian, additional, Clayton, Matthew, additional, Cocu, Simona, additional, Collyer, Thomas, additional, Colvin, Carie, additional, Cope, Sean, additional, Copeta, Filomena, additional, Copotoiu, Sanda-Maria, additional, Correia de Barros, Filinto, additional, Corso, Ruggero Massimo, additional, Cortegiani, Andrea, additional, Costa, Gabriela, additional, Cowton, Amanda, additional, Cox, Nicolas, additional, Craig, James, additional, Cricca, Valentina, additional, Cronin, John, additional, Cunha, Mariana, additional, Cuomo, Arturo, additional, Curley, Katherine, additional, Czuczwar, Mirosław, additional, Dabrowska, Domenika, additional, Damster, Sabrine, additional, Danguy des Déserts, Marc, additional, Daniliuc, Aura, additional, Danninger, Thomas, additional, Darwish, Imad, additional, Dascalu, Corina, additional, Davies, Kirsty, additional, Davies, Simon, additional, De Boer, Hans, additional, De Flaviis, Adelisa, additional, De Selincourt, Gabrielle, additional, Deana, Cristian, additional, Debaene, Bertrand, additional, Debreceni, Gabor, additional, Dedhia, Jatin, additional, Delgado Garcia, Isabel, additional, Della Rocca, Giorgio, additional, Delroy-Buelles, Llana, additional, Desai, Tejal, additional, Dhillon, Parveen, additional, Di Giacinto, Ida, additional, Di Mauro, Piero, additional, Diaz Gomez, Tamara V., additional, Dimitrovski, Aleksandar, additional, Dinic, Vesna, additional, Dîrzu, Dan-Sebastian, additional, Divander, Mona Britt, additional, Dolinar, Janez, additional, Domingues, Susana, additional, Doolan, James, additional, Downes, Charlotte, additional, Dragoescu, Nicoleta Alice, additional, Droc, Gabriela, additional, Dum, Elisabeth, additional, Dumitrescu, Alexandra, additional, Duncan, Louise, additional, Dzurňáková, Paul, additional, Eberl, Susanne, additional, Edwards, Jayne, additional, Edwards, Mark, additional, Ekelund, Kim, additional, Ekengren, Patrik, additional, Elghouty, Eyad, additional, Ellerkmann, Richard, additional, Ellis, Helen, additional, Elme, Andreas, additional, Ernst, Thomas, additional, Errando, Carlos Luis, additional, Estenes, Simao, additional, Ewaldsson, Callis, additional, Farid, Nahla, additional, Featherstone, James, additional, Febres, Daniela, additional, Fedorov, Sergey, additional, Feggeler, Johanna, additional, Feijten, Prisca, additional, Fellmann, Tobias, additional, Fernandez Candil, Juan, additional, Fernandez Castineira, Ana, additional, Fernández Castineira, Juan, additional, Fernando, Aruna, additional, Ferrando, Carlos, additional, Ferreira, Leonia, additional, Ferreira, Patrick, additional, Feyling, Anders, additional, Filipescu, Daniela, additional, Fleischer, Andreas, additional, Floris, Leda, additional, Foerster, Urs, additional, Fox, Benjamin, additional, Franke, Uwe, additional, Frasca, Denis, additional, Frey, Christian, additional, Frost, Victoria, additional, Fullin, Giorgio, additional, Fumagalli, Jacopo, additional, Furneval, Julie, additional, Fusari, Maurizio, additional, Gallacher, Stuart, additional, Galushka, Svetlana, additional, Gambale, Giorgio, additional, Gambino, Irene, additional, Garcia-Perez, Maria Luisa, additional, Garg, Sanjeev, additional, Garlak, Justyna, additional, Gavranovic, Zeljka, additional, Gavrilov, Roman, additional, Gaynor, Lames, additional, Gecaj Gashi, Agreta, additional, Georghiou, Maria, additional, Gerjevic, Bozena, additional, Gferer, Gudrun, additional, Giarratano, Antonino, additional, Gibson, Andy, additional, Gievski, Vanja, additional, Giles, Julian, additional, Gillberg, Lars, additional, Gilowska, Katarzyna, additional, Gilsanz Rodriguez, Fernando, additional, Gioia, Antonio, additional, Giovannoni, Cecilia, additional, Girotra, Vandana, additional, Gkinas, Dimitrios, additional, Gkiokas, George, additional, Godoroja, Daniela, additional, Goebel, Ulrich, additional, Goel, Vandana, additional, Gonzalez, Matilde, additional, Goranovic, Tatjana, additional, Gornik-Wlaszczuk, Ewa, additional, Gosavi, Smita, additional, Gottfridsson, peter, additional, Gottschalk, André, additional, Granell, Manuel, additional, Granstrom, Anna, additional, Grassetto, Alberto, additional, Greenwood, Anna, additional, Grigoras, Ioana, additional, Grintescu, Ioana, additional, Gritsan, Alexey, additional, Gritsan, Galina, additional, Grynyuk, Andriy, additional, Guadagnin, Giovanni Maria, additional, Guarnieri, Marcello, additional, Güçlü, Çiğdem, additional, Guerrero Diez, Maria, additional, Gunenc, Ferim, additional, Günther, Ulf, additional, Gupta, Pawan, additional, Guttenthaler, Vera, additional, Hack, Yvonne, additional, Hafisayena, Ade, additional, Hagau, Natalia, additional, Haldar, Jagannath, additional, Hales, Dawn, additional, Hancı, Volkan, additional, Hanna-Jumma, Sameer, additional, Harazim, Hana, additional, Harlet, Pierre, additional, Harper, Daniel, additional, Harris, Benjamin, additional, Harvey, Orla, additional, Hashimi, Medita, additional, Hawkins, Lesley, additional, Hayes, Conrad, additional, Heaton, James, additional, Heier, Tom, additional, Helliwell, Laurence, additional, Hemmes, Sabrine, additional, Henderson, Kate, additional, Hermanides, Jeroen, additional, Hermanns, Henning, additional, Herrera Hueso, Berta, additional, Hestenes, Siv, additional, Hettiarachchi, Roshane, additional, Highgate, Judith, additional, Hodgson, Keith, additional, Hoelbling, Daniel, additional, Holland, Jonathan, additional, Horhota, Lucian, additional, Hormis, Anil, additional, Hribar, Renata, additional, Hua, Alina, additional, Humphreys, Sally, additional, Humphries, Ryan, additional, Humpliková, Simona, additional, Hunt, Janez, additional, Husnain, Ali, additional, Hussein, Ahmed, additional, Hyams, Benjamin, additional, Iannuccelli, Fabrizio, additional, Ilette, Katie, additional, Ilyas, Carl, additional, Inan, Turgay, additional, India, Immaculada, additional, Ionițăv, Victor, additional, Irwin, Foo, additional, Jain, Vipul, additional, Janez, Benedikt, additional, Jankovic, Radmilo, additional, Jenkins, Sarah, additional, Jenko, Matej, additional, Jimenez, Raquel, additional, Jiménez Gomez, Bárbara, additional, Joachim, Sugganthi, additional, Joelsson-Alm, Eva, additional, John, John, additional, Jonikaite, Lina, additional, Jovic, Miomir, additional, Jungwirth, Bettina, additional, Junke, Etienne, additional, Kabakov, Borys, additional, Kadaoui, Salah-Din, additional, Kanski, Andrzej, additional, Karadag, Süheyla, additional, Karbonskiene, Aurika, additional, Karjagin, Juri, additional, Kasnik, Darja, additional, Katanolli, Fatos, additional, Katsika, Eleni, additional, Kaufmann, Kai, additional, Keane, Helen, additional, Kelly, Martin, additional, Kent, Melanie, additional, Keraitiene, Grazina, additional, Khudhur, Ahmed, additional, Khuenl-Brady, Karin, additional, Kidd, Laurie, additional, King, Siobhan, additional, Kirchgäßner, Katharina, additional, Klancir, Tino, additional, Klucniks, Andris, additional, Knotzer, Johann, additional, Knowlden, Peter, additional, Koers, Lena, additional, Kompan, Janez, additional, Koneti, Kiran K, additional, Kooij, Fabian, additional, Koolen, Eric, additional, Koopman - van Gemert, Anna Wilhelmina Margaretha Maria, additional, Kopp, Kristen, additional, Korfiotis, Dimitrios, additional, Korolkov, Oleg, additional, Kosinová, Martina, additional, Köstenberger, Markus, additional, Kotzinger, Oskar, additional, Kovačević, Marko, additional, Kranke, Peter, additional, Kranke, Eva, additional, Kraus, Christiane, additional, Kraus, Stephanie, additional, Kubitzek, Christiane, additional, Kucharski, Rafal, additional, Kucukguclu, Semih, additional, Kudrashou, Allaksandr, additional, Kumar, Vinayak, additional, Kummen, Live, additional, Kunit, Cornelia, additional, Kushakovsky, Vlad, additional, Kuvaki, Bahar, additional, Kuzmanovska, Biljana, additional, Kyttari, Aikaterina, additional, Landoni, Giovanni, additional, Lau, Gary, additional, Lazarev, Konstantin, additional, Legett, Samantha, additional, Legrottaglie, Anna Maria, additional, Leonardi, Silvia, additional, Leong, Maria, additional, Lercher, Helene, additional, Leuvrey, Matthieu, additional, Leva, Brigitte, additional, Levstek, Meta, additional, Limb, James, additional, Lindholm, Espen, additional, Linton, Fiona, additional, Liperi, Corradero, additional, Lipski, Fabian, additional, Lirk, Philipp, additional, Lisi, Alberto, additional, Lišková, Katarina, additional, Lluch Oltra, Aitana, additional, Loganathan, Vinothan, additional, Lombardi, Stefania, additional, Lopez, Eloisa, additional, Lopez Rodríguez, Maria, additional, Lorenzini, Laura, additional, Lowicka, Malgorzata, additional, Lugovoy, Alexander, additional, Luippold, Madeleine, additional, Lumb, Andrew, additional, Macas, Andrius, additional, Macgregor, Mark, additional, Machado, Humberto, additional, Maciariello, Maria, additional, Madeira, Isabel, additional, Maitan, Stefan, additional, Majewski, Jacek, additional, Maldini, Branka, additional, Malewski, Georgia, additional, Manfredini, Livia, additional, Männer, Olja, additional, Marchand, Bahareh, additional, Marcu, Alexandra, additional, Margalef, Jordi, additional, Margarson, Michael, additional, Marinheiro, Lucia, additional, Markic, Ana, additional, Markovic Bozic, Jasmina, additional, Marrazzo, Francesco, additional, Martin, Jane, additional, Martin Ayuso, Maria, additional, Martinez, Esteher, additional, Martino, Enrico Antonio, additional, Martinson, Victoria, additional, Marusic-Gaser, Katarina, additional, Mascarenhas, Catia, additional, Mathis, Cindy, additional, Matsota, Paraskevi, additional, Mavrommati, Eleni, additional, Mazul Sunko, Branka, additional, McCourt, Killian, additional, McGill, Neil, additional, McKee, Raymond, additional, Meço, Başak Ceyda, additional, Meier, Sonja, additional, Melbourne, Susan, additional, Melbybråthen, Grethe, additional, Meli, Andrea, additional, Melia, Aiden, additional, Melotti, Rita Maria, additional, Menga, Maria Rosaria, additional, Mercer, Pauline, additional, Merotra, Susan, additional, Mescolini, Silvia, additional, Metterlein, Thomas, additional, Michalov, Martin, additional, Michlig, Sam, additional, Midgley, Susan, additional, Milić, Morena, additional, Milojevic, Milan, additional, Miñana, Amanda, additional, Minto, Gary, additional, Mirabella, Lucia, additional, Mirea, Liliana, additional, Mittelstädt, Ludger, additional, Moeglen, Aude, additional, Moise, Alida, additional, Mokini, Zhirajr, additional, Molin, Anna, additional, Moltó, Luis, additional, Monea, Maria Concetta, additional, Montalto, Francesca, additional, Montgomery, Jane, additional, Montgomery, Claire, additional, Montillo, Gerardo, additional, Moore, Sally, additional, Moore, Faye, additional, Moreira, Zelia, additional, Moreno, Tania, additional, Moreno, Ricardo, additional, Moret, Enrique, additional, Moreton, Sarah, additional, Morgan, Marianne, additional, Moro Velasco, Concepción, additional, Morri, Davide, additional, Moull, Alice, additional, Moura, Fernando, additional, Mráz, Peter, additional, Mrozek, Katarzyna, additional, Mukhtar, Karim, additional, Muniyappa, Sudeshkumar, additional, Murray, Heather, additional, Murthy, Burra VS, additional, Mushambi, Mary, additional, Nadolski, Maria, additional, Nardelli, Pasquale, additional, Nardin, Giordano, additional, Navarro Pérez, Rosalía, additional, Naveiro, Andrea, additional, Negri, Manuela, additional, Nesek Adam, Visnja, additional, Neskovic, Vojislava, additional, Neuwersch, Stefan, additional, Neves, Miriam, additional, Nguyen, Bavinh, additional, Ní Eochagáin, Aisling, additional, Nicholas, Caroline, additional, Nightingale, Jeremy, additional, Norrie, Kylie, additional, Novak-Jankovic, Vesna, additional, Novakova, Andrea, additional, Novillo, Marta, additional, Numan, Sandra, additional, Oduro-Dominah, Louise, additional, Oldner, Anders, additional, Oliveira, Isabel, additional, Ologoiu, Daniela, additional, Oloktsidou, Irini, additional, O'Reilly, Rosalind, additional, Orlando, Alessandro, additional, Ovezov, Alexey, additional, Ozbilgin, Sule, additional, Paal, Peter, additional, Padin Barreiro, Lidia, additional, Palugniok, Ryszard, additional, Papaioannou, Alexandra, additional, Papapostolou, Konstantinos, additional, Paranthaman, Prabhakar, additional, Pardey Bracho, Gilda, additional, Parente, Suzana, additional, Parfeni, Alexandru, additional, Pasin, Laura, additional, Passey, Samuel, additional, Pastor, Ernesto, additional, Patch, Sarah, additional, Patil, Andan, additional, Paunescu, Marilena-Alina, additional, Pehboeck, Daniel, additional, Pereira, Manuela, additional, Pereira, Carla, additional, Perez Caballero, Paula, additional, Pérez García, Aníbal, additional, Pérez Soto, Antonia, additional, Perez Tejero, Gisela, additional, Perez-Cerda, Francisco, additional, Pesenti, Antonio, additional, Petta, Rocco, additional, Philippe, Simon, additional, Pickering, David, additional, Pico Veloso, Jandro, additional, Pina, Pedro, additional, Pinho-Oliveira, Vítor, additional, Pinol, Santiago, additional, Pinto, Rita, additional, Pistidda, Laura, additional, Pitterle, Manuela, additional, Piwowarczyk, Paweł, additional, Plotnikova, Olga, additional, Pohl, Holger, additional, Poldermann, Jorinde, additional, Polkovicová, Lucia, additional, Pompei, Livia, additional, Popescu, Mihai, additional, Popović, Radmila, additional, Pota, Vincenzo, additional, Potocnik, Miriam, additional, Potręć, Beata, additional, Potter, Alison, additional, Pramod, Nalwaya, additional, Prchalova, Martina, additional, Preckel, Benedikt, additional, Pugh, Richard, additional, Pulletz, Mark, additional, Radoeshki, Aleksandar, additional, Rafi, Amir, additional, Ragazzi, Riccardo, additional, Raineri Santi, Maurizio, additional, Rajamanickam, Tamiselvan, additional, Rajput, Zahra, additional, Ramachandran, Rajeskar, additional, Ramasamy, Radhika, additional, Ramessur, Suneil, additional, Rao, Roshan, additional, Rasmussen, Anders, additional, Rato, André, additional, Razaque, Usman, additional, Real Navacerrada, M. Isabel, additional, Reavley, Caroline, additional, Reid, James, additional, Reschreiter, Henrik, additional, Rial, Erick, additional, Ribas Carrasco, Patricia, additional, Ribeiro, Sandy, additional, Rich, Nathalie, additional, Richardson, Lydia, additional, Rimaitis, Kestutis, additional, Rimaitis, Marius, additional, Ringvold, Else-Marie, additional, Ripke, Fabian, additional, Ristescu, Irina, additional, Ritchie, Keith, additional, Ródenas, Frederic, additional, Rodrigues, Patrícia, additional, Rogers, Emma, additional, Rogerson, David, additional, Romagnoli, Stefano, additional, Romero, Esther, additional, Rondovic, Goran, additional, Rose, Bernd Oliver, additional, Roth, Winfried, additional, Rotter, Marie-Therese, additional, Rousseau, Guy, additional, Rudjord, Anders, additional, Rueffert, Henrik, additional, Rundgren, Malin, additional, Rupprecht, Korbinian, additional, Rushton, Andrew, additional, Russotto, Vincenzo, additional, Rypulak, Elżbieta, additional, Ryszka, Maciej, additional, Sà, Jacinta, additional, Sà Couto, Paula, additional, Saby, Sandrine, additional, Sagic, Jelena, additional, Saleh, Omar, additional, Sales, Gabriele, additional, Sánchez Sánchez, Yván, additional, Sanghera, Sumayer, additional, Şanli Karip, Ceren, additional, Santiveri Papiol, Francisco Javier, additional, Santos, Sofia, additional, Sarno, Stephen, additional, Saul, Daniel, additional, Saunders, David, additional, Savic, Nenad, additional, Scalco, Loïc, additional, Scanlon, Deborah, additional, Schaller, Stefan, additional, Schax, Christoph, additional, Scheffer, Gert Jan, additional, Schening, Anna, additional, Schiavone, Vincenzo, additional, Schmidt-Ehrenberg, Florian, additional, Schmidt-Mutter, Catherine, additional, Schönberg, Christina, additional, Schopflin, Christian, additional, Schreiber, Jan-Uwe, additional, Schultz, Marcus, additional, Schurig, Marlen, additional, Scott, Carmen, additional, Sebestian, Siby, additional, Sehgal, Selena, additional, Sem, Victoria, additional, Semenas, Egidijus, additional, Serafini, Elena, additional, Serchan, Pashalitsa, additional, Shields, Martin, additional, Shobha, Ramakrishnan, additional, Shosholcheva, Mirjana, additional, Siamansour, Tanja, additional, Siddaiah, Narendra, additional, Siddiqi, Khalid, additional, Sinclair, Rhona, additional, Singh, Permendra, additional, Singh, Rajendra, additional, Sinha, Aneeta, additional, Sinha, Ashok, additional, Skinner, Amanda, additional, Smee, Elizabeth, additional, Smekalova, Olga, additional, Smith, Neil, additional, Smith, Thomas, additional, Smitz, Carine, additional, Smole, Daniel, additional, Sojčić, Nataša, additional, Soler Pedrola, Maria, additional, Somanath, Sameer, additional, Sonksen, Julian, additional, Sorella, Maria Christina, additional, Sörmus, Alar, additional, Soro, Marina, additional, Soto, Carmen, additional, Spada, Anna, additional, Spadaro, Savino, additional, Spaeth, Johannes, additional, Sparr, Harald, additional, Spielmann, Annika, additional, Spindler-Vesel, Alenka, additional, Stamelos, Matthaios, additional, Stancombe L, Liucia, additional, Stanculescu, Andreea, additional, Standl, Thomas, additional, Standley, Tom, additional, Stanek, Ondrej, additional, Stanisavljević, Snežana, additional, Starczewska, Malgorzata, additional, Stäuble, Christiane, additional, Steen, Julie, additional, Stefan, Oana Maria, additional, Stell, Elizabeth, additional, Stera, Caterina, additional, Stevens, Markus, additional, Stoerckel, Marlène, additional, Stošić, Biljana, additional, Stourac, Petr, additional, Stroumpoulis, Konstantinos, additional, Struck, Rafael, additional, Suarez de la Rica, Alejandro, additional, Sultanpori, Altaf, additional, Sundara Rajan, Rajinikanth, additional, Suying, Ong, additional, Svensen, Christer, additional, Swan, Louise, additional, Syrogianni, Paulina, additional, Sysiak, Justyna, additional, Szederjesi, Janos, additional, Taddei, Stefania, additional, Tan Hao, Ern, additional, Tanou, Virginia, additional, Tarabová, Katarina, additional, Tardaguila Sancho, Paula, additional, Tarroso, Maria, additional, Tartaglione, Marco, additional, Taylor, Emma, additional, Tbaily, Lee, additional, Telford, Richard, additional, Terenzoni, Massimo, additional, Theodoraki, Kassiani, additional, Thornley, Helen, additional, Tiganiuc, Liviu, additional, Toim, Hardo, additional, Tomescu, Dana, additional, Tommasino, Concezione, additional, Toni, Jessica, additional, Toninelli, Arturo, additional, Toretti, Ilaria, additional, Townley, Stephen, additional, Trepenaitis, Darius, additional, Trethowan, Brian, additional, Tsaousi, Georgia, additional, Tsiftsi, Aikaterini, additional, Tudor, Adrada, additional, Turan, Güldem, additional, Turhan, Sanem Çakar, additional, Unic-Stojanovic, Dragana, additional, Unterbuchner, Christoph, additional, Unzueta, Carmen, additional, Uranjek, Jasna, additional, Ursic, Tomaz, additional, Vaida, Simona, additional, Valldeperas Ferrer, Silvia, additional, Valldeperas Hernandez, Maria Inmaculada, additional, Valsamidis, Dimitri, additional, Van Beek, Rienk, additional, Van dasselaer, Nick, additional, Van Der Beek, Tim, additional, Van Duivenvoorde, Yoni, additional, van Klei, Wilton A., additional, Van Poorter, Frans, additional, Van Zaane, Bas, additional, Van Zundert, Tom, additional, Van Zyl, Rebekka, additional, Vargas Munoz, Ana Milena, additional, Varsani, Nimu, additional, Vasconcelos, Pedro, additional, Vassilakis, Georgios, additional, Vecchiatini, Tommaso, additional, Vecera, Lubomir, additional, Vercauteren, Marcel, additional, Verdouw, Bas, additional, Verheyen, Veerle, additional, Verri, Marco, additional, Vicari Sottosanti, Luigi Giancarlo, additional, Vico, Manuel, additional, Vidal Mitjans, Patricia, additional, Vilardi, Anna, additional, Vissicchio, Daniela, additional, Vitale, Giovanni, additional, Vitković, Bibiana, additional, Vizcaychipi, Marcela Paola, additional, Voicu, Alexandra, additional, Voje, Minca, additional, Volfová, Ivana, additional, Volta, Carlo Alberto, additional, Von Lutterotti, Theresa, additional, von Tiesenhausen, Anna, additional, Vrecic-Slabe, Simona, additional, Vukcevic, Dejan, additional, Vukovic, Rade, additional, Vullo, P. Agostina, additional, Wade, Andrew, additional, Wallberg, Hanna, additional, Wallden, Jakob, additional, Wallner, Johann, additional, Walther Sturesson, Louise, additional, Watson, Davina, additional, Weber, Stefan, additional, Wegiel Leskiewiq, Anna, additional, Weller, Debbie, additional, Wensing, Carine, additional, Werkmann, Markus, additional, Westberg, Henrik, additional, Wikström, Erik, additional, Williams, Benedict, additional, Wilson, Robin, additional, Wirth, Steffen, additional, Wittmann, Maria, additional, Wood, Laura, additional, Wright, Stella, additional, Zachoval, Christian, additional, Zambon, Massimo, additional, Zampieri, Silvia, additional, Zampone, Salvatore, additional, Zangrillo, Alberto, additional, Zani, Gianluca, additional, Zavackiene, Asta, additional, Zieglerder, Raphael, additional, Zonneveldt, Harry, additional, Zsisku, Lajos, additional, Zucker, Tom-Philipp, additional, Żukowski, Maciej, additional, Zuleika, Mehrun, additional, and Zupanĕiĕ, Darja, additional
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- 2019
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43. The GlyT1 Inhibitor Bitopertin Ameliorates Allodynia and Hyperalgesia in Animal Models of Neuropathic and Inflammatory Pain
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Armbruster, Anja, primary, Neumann, Elena, additional, Kötter, Valentin, additional, Hermanns, Henning, additional, Werdehausen, Robert, additional, and Eulenburg, Volker, additional
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- 2018
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44. Influence on number of top-ups after implementing patient controlled epidural analgesia: A cohort study
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van Samkar, Ganapathy, primary, Hermanns, Henning, additional, Lirk, Philipp, additional, Hollmann, Markus W., additional, and Stevens, Markus F., additional
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- 2017
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45. The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain
- Author
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Werdehausen, Robert, Mittnacht, Sebastian, Bee, Lucy A., Minett, Michael S., Armbruster, Anja, Bauer, Inge, Wood, John N., Hermanns, Henning, Eulenburg, Volker, Graduate School, and Anesthesiology
- Subjects
Lidocaine metabolites ,Male ,Pain Threshold ,Inflammatory pain ,Freund's Adjuvant ,Glycine ,Glutamic Acid ,Motor Activity ,Neuropathic pain ,Glycine transporter ,Membrane Potentials ,Mice ,Xenopus laevis ,Receptors, Glycine ,Physical Stimulation ,Animals ,N-ethylglycine ,Pain Measurement ,Analgesics ,Mice, Inbred C57BL ,Posterior Horn Cells ,Disease Models, Animal ,Spinal Cord ,N-substituted Glycines ,Neuralgia ,Neurogenic Inflammation ,Glycinergic inhibition ,Research Paper - Abstract
Supplemental Digital Content is Available in the Text. The lidocaine metabolite N-ethylglycine specifically reduces GlyT1-dependent glycine uptake and has antinociceptive effects in experimental inflammatory and neuropathic pain, while no adverse effects are observed., Glycine transporter 1 (GlyT1) plays a crucial role in regulating extracellular glycine concentrations and might thereby constitute a new drug target for the modulation of glycinergic inhibition in pain signaling. Consistent with this view, inhibition of GlyT1 has been found to induce antinociceptive effects in various animal pain models. We have shown previously that the lidocaine metabolite N-ethylglycine (EG) reduces GlyT1-dependent glycine uptake by functioning as an artificial substrate for this transporter. Here, we show that EG is specific for GlyT1 and that in rodent models of inflammatory and neuropathic pain, systemic treatment with EG results in an efficient amelioration of hyperalgesia and allodynia without affecting acute pain. There was no effect on motor coordination or the development of inflammatory edema. No adverse neurological effects were observed after repeated high-dose application of EG. EG concentrations both in blood and spinal fluid correlated with an increase of glycine concentration in spinal fluid. The time courses of the EG and glycine concentrations corresponded well with the antinociceptive effect. Additionally, we found that EG reduced the increase in neuronal firing of wide-dynamic-range neurons caused by inflammatory pain induction. These findings suggest that systemically applied lidocaine exerts antihyperalgesic effects through its metabolite EG in vivo, by enhancing spinal inhibition of pain processing through GlyT1 modulation and subsequent increase of glycine concentrations at glycinergic inhibitory synapses. EG and other substrates of GlyT1, therefore, may be a useful therapeutic agent in chronic pain states involving spinal disinhibition.
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- 2015
46. MicroRNA-1-associated effects of neuron-specific brain-derived neurotrophic factor gene deletion in dorsal root ganglia
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Neumann, Elena, primary, Brandenburger, Timo, additional, Santana-Varela, Sonia, additional, Deenen, René, additional, Köhrer, Karl, additional, Bauer, Inge, additional, Hermanns, Henning, additional, Wood, John N., additional, Zhao, Jing, additional, and Werdehausen, Robert, additional
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- 2016
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47. Local Anesthetic-Induced Neurotoxicity
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Verlinde, Mark, primary, Hollmann, Markus, additional, Stevens, Markus, additional, Hermanns, Henning, additional, Werdehausen, Robert, additional, and Lirk, Philipp, additional
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- 2016
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48. Lidocaine metabolites inhibit glycine transporter 1 a novel mechanism for the analgesic action of systemic lidocaine?
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Werdehausen, Robert, Kremer, David, Brandenburger, Timo, Schlösser, Lukas, Jadasz, Janusz, Küry, Patrick, Bauer, Inge, Aragón, Carmen, Eulenburg, Volker, Hermanns, Henning, Anesthesiology, ACS - Heart failure & arrhythmias, APH - Quality of Care, ANS - Neuroinfection & -inflammation, ACS - Diabetes & metabolism, and AII - Inflammatory diseases
- Abstract
Background: Lidocaine exerts antinociceptive effects when applied systemically. The mechanisms are not fully understood but glycinergic mechanisms might be involved. The synaptic glycine concentration is controlled by glycine transporters. Whereas neurons express two types of glycine transporters, astrocytes specifically express glycine transporter 1 (GlyT1). This study focuses on effects of lidocaine and its major metabolites on GlyT1 function. Methods: The effects of lidocaine and its metabolites monoethylglycinexylidide (MEGX), glycinexylidide, and N-ethylglycine on GlyT1 function were investigated in uptake experiments with [ 14C]-labeled glycine in primary rat astrocytes. Furthermore, the effect of lidocaine and its metabolites on glycine-induced currents were investigated in GlyT1-expressing Xenopus laevis oocytes. Results: Lidocaine reduced glycine uptake only at toxic concentrations. The metabolites MEGX, glycinexylidide, and N-ethylglycine, however, significantly reduced glycine uptake (P < 0.05). Inhibition of glycine uptake by a combination of lidocaine with its metabolites at a clinically relevant concentration was diminished with increasing extracellular glycine concentrations. Detailed analysis revealed that MEGX inhibits GlyT1 function (P < 0.05), whereas Nethylglycine was identified as an alternative GlyT1 substrate (EC 50 = 55 μM). Conclusions: Although lidocaine does not function directly on GlyT1, its metabolites MEGX and glycinexylidide were shown to inhibit GlyT1-mediated glycine uptake by at least two different mechanisms. Whereas glycinexylidide was demonstrated to be an alternative GlyT1 substrate, MEGX was shown to inhibit GlyT1 activity in both primary astrocytes and in GlyT1-expressing Xenopus laevis oocytes at clinically relevant concentrations. These findings provide new insights into the possible mechanisms for the antinociceptive effect of systemic lidocaine.
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- 2012
49. Glycine transporter GlyT1, but not GlyT2, is expressed in rat dorsal root ganglion—Possible implications for neuropathic pain
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Schlösser, Lukas, primary, Barthel, Franziska, additional, Brandenburger, Timo, additional, Neumann, Elena, additional, Bauer, Inge, additional, Eulenburg, Volker, additional, Werdehausen, Robert, additional, and Hermanns, Henning, additional
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- 2015
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50. Expression Changes of MicroRNA-1 and its Targets Connexin 43 and Brain-Derived Neurotrophic Factor in the Peripheral Nervous System of Chronic Neuropathic Rats
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Neumann, Elena, primary, Hermanns, Henning, additional, Barthel, Franziska, additional, Werdehausen, Robert, additional, and Brandenburger, Timo, additional
- Published
- 2015
- Full Text
- View/download PDF
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