35 results on '"Harlan, John E"'
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2. Structure of BcI-X$_L$-Bak Peptide Complex: Recognition between Regulators of Apoptosis
3. Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery
4. A potent erythropoietin-mimicking human antibody interacts through a novel binding site
5. Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design
6. NMR studies of the anti-apoptotic protein Bcl-x(sub.L) in micelles
7. From Bacterial Genomes to Novel Antibacterial Agents: Discovery, Characterization, and Antibacterial Activity of Compounds that Bind to HI0065 (YjeE) from Haemophilus influenzae
8. NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor trio
9. Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure
10. X-ray and NMR structure of human Bcl-x(sub L), an inhibitor of programmed cell death
11. Structure and ligand recognition of the phosphotyrosine binding domain of Shc
12. Structural characterization of the interaction between a pleckstrin homology domain and phosphatidylinositol 4,5-biphosphate
13. X-ray and NMR structure of human Bcl-x sub L, an inhibitor of programmed cell death
14. Abstract 2783: Empowering therapeutic monoclonal antibodies with IFN-alpha for cancer immunotherapy
15. Structural characterization of a soluble amyloid [beta]-peptide oligomer
16. Observations of Xyleborus affinis Eichhoff (Coleoptera:Curculionidae:Scolytinae) in Central Michigan
17. Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs
18. Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195
19. On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1
20. Iniparib Nonselectively Modifies Cysteine-Containing Proteins in Tumor Cells and Is Not a Bona Fide PARP Inhibitor
21. Recombinant kringle 5 from plasminogen antagonises hepatocyte growth factor-mediated signalling
22. Structural Characterization of a Soluble Amyloid β-Peptide Oligomer
23. P2-483: Biophysical characterization of soluble amyloid-β peptide oligomers
24. A highly potent and selective farnesyltransferase inhibitor ABT-100 in preclinical studies
25. Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization
26. The BH3 Domain of Bcl-x S Is Required for Inhibition of the Antiapoptotic Function of Bcl-x L
27. Structure of Bcl-x L -Bak Peptide Complex: Recognition Between Regulators of Apoptosis
28. X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
29. Binding Affinities of Tyrosine-phosphorylated Peptides to the COOH-terminal SH2 and NH2-terminal Phosphotyrosine Binding Domains of Shc
30. Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
31. Structural Characterization of a Soluble Amyloid β-Peptide Oligomer.
32. The BH3 Domain of Bcl-xSIs Required for Inhibition of the Antiapoptotic Function of Bcl-xL
33. Evidence for a Requirement for Both Phospholipid and Phosphotyrosine Binding via the Shc Phosphotyrosine-Binding Domain In Vivo
34. Bad Is a BH3 Domain-Containing Protein That Forms an Inactivating Dimer with Bcl-XL
35. Structural characterization of a soluble amyloid beta-peptide oligomer.
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