7,068 results on '"Growth and Development"'
Search Results
2. National Survey To Validate General Growth Outcomes for Children between Birth and Age Eight: Initial Results. Technical Report #3.
- Author
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Minnesota Univ., Minneapolis. Early Childhood Research Inst. on Measuring Growth and Development., McConnell, Scott, McEvoy, Mary, and Carta, Judith J.
- Abstract
This monograph reports on a national mail survey to validate a set of general growth outcomes for children, including those with disabilities, between birth and age 8. The survey was part of a 5-year project to create a comprehensive measurement system to track the developmental progress of individual children with disabilities in this age range as well as to help families and professional educators generate interventions to facilitate children's growth over time. Surveys were sent to 1,099 parents of children with and without disabilities, as well as 1,275 professionals in early childhood and early elementary education. Respondents (351 parents and 672 professionals) were asked to rate the importance of 15 general growth outcomes describing young children's developmental trajectories between birth and age 8. Results indicate parents and professionals overwhelmingly supported the selected outcomes. Results are evaluated in terms of parental and professional acceptance of outcomes, applicability to subgroups of children, and limitations. Appendices include a list of outcomes and both parent and professional surveys. (DB)
- Published
- 1998
3. Family Outcomes in a Growth and Development Model. Technical Report #7.
- Author
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Minnesota Univ., Minneapolis. Early Childhood Research Inst. on Measuring Growth and Development., McConnell, Scott, McEvoy, Mary, and Carta, Judith J.
- Abstract
This paper reports on the development of a set of four family outcomes concerned with the measurement of child growth and development as part of a 5-year project by the Early Childhood Research Institute on Measuring Growth and Development to develop a comprehensive assessment model for young children, birth to age 8, with disabilities. It first lists 11 family outcomes identified as a result of interviews with parents of children with disabilities. It then explains the four outcomes selected to be part of the model: (1) families will have a basic understanding of child development and will be able to identify needs for their child, including those related to cultural, linguistic or disability specific issues; (2) families will be able to assess how their child's development is progressing related to general outcomes identified on the Individualized Education Program/Individual Family Service Plan; (3) families will be confident in their abilities to make choices about interventions for their child and will be able to implement those interventions effectively; and (4) families will feel that their beliefs and values are respected by other members of their child's team and will see themselves as equal and integral members. Future research plans include validation of the four outcomes and selection of additional outcomes. (DB)
- Published
- 1998
4. Research and Development of Individual Growth and Development Indicators for Children between Birth to Age Eight. Technical Report #4.
- Author
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Minnesota Univ., Minneapolis. Early Childhood Research Inst. on Measuring Growth and Development., McConnell, Scott, McEvoy, Mary, and Carta, Judith J.
- Abstract
This document provides an overview of the rationale for, and characteristics of, individual growth and development indicators (IGDIs) for children birth to age 8 and their families. Development of such indicators is part of a 5-year project by the Early Childhood Research Institute Measuring Growth and Development to conduct research on, develop, and disseminate a comprehensive program performance measurement system for early intervention, preschool, and primary-grade programs serving children with disabilities and their families. The IGDIs are intended to describe children's growth and development over time, and thus to indicate when this progress is on-track toward some desired outcome, or when different or more intensive intervention is needed. This paper looks at the purpose and conceptual foundation for IGDI assessment, describes essential and desirable features of these measures, offers examples of possible IGDIs, and reports findings from the initial research on these measures. (Contains 42 references.) (DB)
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- 1998
5. Selection of General Growth Outcomes for Children between Birth and Age Eight. Technical Report #2.
- Author
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Minnesota Univ., Minneapolis. Early Childhood Research Inst. on Measuring Growth and Development., McConnell, Scott, McEvoy, Mary, and Carta, Judith J.
- Abstract
This document reports on development of a comprehensive system for measuring the ongoing development of children with disabilities from birth to age 8. A multi-step process was used to identify a set of general growth outcomes for children in this age range and to begin formulating individualized indicators of growth and development, as well as additional assessment tools. A set of 15 outcomes was identified spanning the scope of developmental competencies usually associated with early childhood education; i.e., communication, motor, social, adaptive, and cognitive domains. Validation of these outcomes was established through a national survey of parents of children with and without disabilities, and professionals in early childhood and early elementary education. The final set of general growth outcomes is organized around the following goals: (1) the child uses language to convey and comprehend communication and social intent; (2) the child takes responsibility for his/her behavior, health, and well-being, even in the face of challenge or adversity; (3) the child negotiates and manipulates the environment; (4) the child initiates, responds to, and maintains positive social relationships; and (5) the child uses cognitive skills to explore the environment, reason, and solve problems. (Contains 17 references.) (DB)
- Published
- 1998
6. Theoretical Foundations of the Early Childhood Research Institute on Measuring Growth and Development: An Early Childhood Problem-Solving Model. Technical Report #6.
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Minnesota Univ., Minneapolis. Early Childhood Research Inst. on Measuring Growth and Development., McConnell, Scott, McEvoy, Mary, and Carta, Judith J.
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This report describes the decision-making model that provides the theoretical framework being developed by the Early Childhood Research Institute on Measuring Growth and Development (ECRI-MGD) in a 5-year project to generate a set of common child and family indicators that can be used within a comprehensive system of service delivery for young children with disabilities, birth to age 8. The report first looks at the current model of assessment and service delivery in early intervention and limitations of the model. These limitations include lack of linkage across assessment phases, lack of linkage to long-term goals, and lack of theoretical framework for decision making. It then explains the rationale for and components of the Problem-Solving Model of decision making. It identifies theoretical assumptions and the two types of assessment tools used, Individual Growth and Development Indicators and Exploring Solutions Assessments. A table provides an overview of the ECRI-MGD Problem-Solving Model including the decision-making phase, questions, and assessment tools and procedures utilized. The final section discusses similarities and differences between the ECRI-MGD Problem Solving Model and the current model of assessment in early intervention. (Contains 21 references.) (DB)
- Published
- 1998
7. Accountability Systems for Children between Birth and Age Eight. Technical Report #1.
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Minnesota Univ., Minneapolis. Early Childhood Research Inst. on Measuring Growth and Development., McConnell, Scott, McEvoy, Mary, and Carta, Judith J.
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This technical report presents issues related to defining and applying accountability systems for young children, including those with disabilities. It notes that reaching shared perspectives on definitions of accountability systems and their constituents remains complicated by the number of levels to which such systems can apply (e.g., child-, family-, state-, or nation-focused) and multiple meanings stakeholders place on frequently used terms (e.g., "outcomes,""indicators," and "benchmarks"). The report addresses limitations imposed by four major issues: (1) the relative novelty of applying such systems to young children; (2) the emphasis on nomothetic and consensus-based approaches; (3) the still-growing state of knowledge on links between early functioning and later competency; and (4) the exclusion of children with disabilities. The report proposes a set of standards to guide development of accountability systems for young children focusing on children's growth and development, feasibility, application to multiple levels of analysis, and generation of important information to all stakeholders. These standards are the foundation of the Early Childhood Research Institute on Measuring Growth and Development, a 5-year collaborative project to create a comprehensive assessment system, aggregate individualized data to describe group-level outcomes, and generate interventions. (Contains 43 references.) (DB)
- Published
- 1998
8. Research and Development of Exploring Solutions Assessments for Children between Birth and Age Eight. Technical Report #5.
- Author
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Minnesota Univ., Minneapolis. Early Childhood Research Inst. on Measuring Growth and Development., McConnell, Scott, McEvoy, Mary, and Carta, Judith J.
- Abstract
This report describes research and development activities concerned with developing a set of tools for planning interventions for individual children, birth to age 8. It is part of a 5-year project to develop a comprehensive system of assessment within a decision-making framework for programs serving children with and without disabilities, birth to age 8. The set of tools, Exploring Solutions Assessment, is described including program features, activity/curriculum-based, and ecobehavioral assessments. Compared to measures of child progress, these measures of potential solutions focus on a child's strengths and weaknesses in the curriculum to identify skills mastered and skills to be taught, child/caregiver behaviors most likely to enable the learning of these skills, and elements of the child's learning environment most responsible for teaching these skills and supporting their generalization. Appendices include a list of program features, a teacher survey, activity-based assessment scripts, and ecobehavioral assessment instrument taxonomies. (Contains 102 references.) (DB)
- Published
- 1998
9. The Effects of Change in Governance Structure on the Practices and Outcomes of an Experienced Teachers' Center. Final Report.
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Wayne State Univ., Detroit, MI. Detroit Center for Professional Growth and Development. and Hockman, Elaine M.
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Board functions, participation, activities, and program outcomes of the Detroit Center for Professional Growth and Development were studied to determine the effects of a change in board membership on the functioning of the center. From 1975 to September 1979, the center's governing board had been composed of key officials, several whom were teachers, of five educational organizations. In October 1979, membership was expanded to include six more teachers in response to federal and state teacher center legislation requiring a teacher majority on such boards. Trend analyses were conducted over a five-year period through examination of documents from board meetings and objective measures of program planning and outcomes for three center components: (1) Field Consultant Service; (2) the Mathematics Education Resource Center; and (3) the Reading Resource Center. Characteristics of the five-member governing board during the first four years differed from those of the 11-member policy board in the fifth year. Fewer board meetings were held, and agendas were less complex in the fifth year. Financial issues remained a major concern for board consideration, although obtaining release time for teachers became a recurring issue in the fifth year. For all five years, teachers were the major participants in motion formulation, and there was very little controversy among board members on the issues. Program decisions continued to be made by the staff of the center, as the board remained primarily concerned with funding aspects of the center's activities. (FG)
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- 1981
10. Stromal Cell-Derived Factor-1 Genotype, Coreceptor Tropism, and HIV Type 1 Disease Progression
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Hemophilia Growth and Development Study, Daar, Eric S., Lynn, Henry S., Donfield, Sharyne M., Lail, Alice, O'Brien, Stephen J., Huang, Wei, and Winkler, Cheryl A.
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- 2005
11. Effect of Hepatitis C Virus Genotype on CD4⁺ T Cell Count in a Cohort of Antiretroviral-Naive HIV-1-Infected Individuals [with Reply]
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Italian Cohort Naive for Antiretrovirals-Hepatitis Study Group, Hemopphilia Growth and Development Study, Antonucci, Giorgio, Cozzi-Lepri, Alessandro, Girardi, Enrico, Capobianchi, Maria Rosaria, De Luca, Andrea, d'Arminio Monforte, Antonella, Daar, Eric S., Yoo, Thomas W., Lail,², Alice, Lynn, Henry S., and Donfield,², Sharine
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- 2005
12. Effect of Hepatitis C Virus (HCV) Genotype on HCV and HIV-1 Disease
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Hemophilia Growth and Development Study, Yoo, Thomas W., Donfield, Sharyne, Lail, Alice, Lynn, Henry S., and Daar, Eric S.
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- 2005
13. The Effects of Word Frequency, Need for Achievement, and Instructional Sets upon Word Recognition Thresholds of Young and Old Subjects.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development., Riegel, Ruth M., and Riegel, Klaus F.
- Abstract
Eighteen young (almost 16 years of age) and 18 old(average age 70) subjects were assigned to either the control or one of two experimental groups on the basis of their age, sex, vocabulary, and need for achievement scores. All participated in a test session and two experimental sessions. Results indicate that: (1) Items that have been often experienced and are repeatedly represented in the storage system of a subject are recognized faster than items that have been experienced less often. (2) For subjects with large accumulated repertoires (old subjects), the effects of experience with new items of varying frequencies will be relatively less marked than for subjects with smaller repertoires (young subjects). Keeping all other factors constant, their recognition thresholds for such new items are higher than for young subjects. (3) There seem to be age differences in long term need states as measured by the need for achievement test. Old subjects seem to rearrange items at a lower speed than young subjects and consequently have lower achievement test scores. (4) Need-arousing instructions hinder the performance of old subjects, but improve the performance of young ones. Because of their large storage, old subjects seem to become confused rather than being supported by this influence. The authors also discuss the need for further research and the implications of such research. (DO)
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- 1968
14. Developmental Trends in the Processing of Task-Relevant and Task-Irrelevant Information.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Druker, Joseph F.
- Abstract
The role of perceptual discrimination in the development of the ability to selectively process information was investigated. Using an incidental learning paradigm, the discriminability between relevant and irrelevant stimuli was experimentally varied in two ways: (1) contiguity versus non-contiguity in spatial arrangements and (2) alternating versus non-alternating arrangements. The subjects were 80 children in each of the fourth, sixth, and eighth grades. It was concluded that the development change responsible for selective information processing did not involve improved visual discrimination. A post-test questionnaire revealed that older subjects were characterized by more efficient encoding and rehearsal strategies which were postulated as the basis for the older subjects' relatively better ability to selectively process information. This paper comprises a report in "Development of Language Functions, A Research Program-Project (Study C: Development of Selective Attention Abilities)." (Author/DO)
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- 1968
15. Central and Incidental Learning in Children.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development., Hagen, John W., and Sabo, Ruth
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Earlier studies found that recall scores of information central to the task increased with age while incidental information recall scores remained constant. This study repeated the earlier ones modifying procedures of instructions, testing, and schedule of recall. Also, it tested the effect of labeling pictorial stimuli. The sample of 253 children were to learn to discriminate either content or position of presented pictures as central information. The sample was divided by three age groups, 7 to 9, 10 to 11, and 12 to 14. These groups were further subdivided into four groups. The first group received more ambiguous directions than did the other groups. The second group was tested on a balanced schedule of recall. The third group was shown names of animals, while the fourth group was shown numbers designating positions of pictures. The results showed that (1) as before, content recall scores increase with age, (2) more ambiguous directions led to less selectivity at all ages, (3) a balanced schedule of recall was effective at an older age, (4) labeling depresses incidental information scores at all ages, and (5) name labeling is more effective than numerical labeling, but not at a significant level. A bibliography and tables are included. (JS)
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- 1968
16. Verbal Labeling and Serial Position Recall.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development., Hagen, John W., and Mesibov, Gary
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The effect of verbal labeling in a serial position short term memory task was investigated. Forty female college students were given 16 trials each. Eight trials involved only central items which had to be recalled. The other eight trials involved both central and incidental items. Half of the subjects verbalized the names of the central items as they were presented. Verbalization was found to decrease short term memory performance. There was no effect of one versus two stimuli per card. The authors feel that these results supplement the past research in this area and support a view that with age the use of rehearsal strategies becomes increasingly dominant. Consequently, labeling inhibits the use of more efficient processing. This paper comprises a report in "Development of Language Functions, a Research Program-Project (Study M: Development of Selective Attention Abilities)." (DO)
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- 1968
17. Comparisons of the Restricted Associations of Chronic Schizophrenic and Normal Control Subjects.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development., Stern, Elliot J., and Riegel, Klaus F.
- Abstract
The associative behavior of 24 male chronic schizophrenics and 24 normal control subjects (male) equated for age and educational level was investigated. Free and restricted associations were obtained to analyze the organizational aspects of associative behavior as well as the number of unique or common responses per task, response repetitions under different task instructions, and agreement in responses among both groups of subjects. The associations of schizophrenics were more variable than those of normal subjects especially on tasks which restricted most the choice of responses. Agreement in responding between normal and schizophrenic subjects was markedly lower when compared with that between high and low creative subjects or with one-year test-retest data of a heterogeneous group. Repetition of responses given to the same stimuli under different instructions was markedly higher for schizophrenics, and thus, the degree of task/response differentiation was reduced. The restricted associations overlapped with free associations more markedly for schizophrenics, but the general structure of a conceptual semantic space was about the same for both groups. The authors feel that when explicit constraint in tasks of verbal associations in high, schizophrenics (more than normals) impose a low degree of implicit constraint upon their verbal behavior; when the external constraint is low, they increase implicit constraing. (Author/DO)
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- 1967
18. A Piagetian Approach to the Learning of Nonsense Material.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Wolff, Peter
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The applicability of Piaget's cognitive processes of assimilation and accommodation to the learning of verbal nonsense syllables (ten low association value consonant-vowel-consonant trigrams) was tested experimentally. Twenty-two undergraduates (ten female and 12 male) at the University of Michigan served as subjects. It was hypothesized that learning rate should be a function of the amount of cognitive adjustment the subject had to make to the stimulus material measured by changes in semantic differential ratings of the stimuli before and after they were learned. Results showed two groups of fast learners, one of which made significantly less changes than the slow learners, and one significantly more. Systematic directional shift on the evaluative, potency, and activity dimensions of the semantic differential were also found. The author feels that these findings lend considerable support for the applicability of Piaget's processes of assimilation and accommodation to the learning process and that identification and investigation of internal processes of this type will be necessary before the learning function of the human organism is understood. This paper comprises a report in "Development of Language Functions, A Research Program-Project." (DO)
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- 1967
19. Induced Versus Spontaneous Rehearsal in Short-Term Memory in Nursery School Children. Study M: Development of Selective Attention Abilities.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development., Kingsley, Phillip R., and Hagen, John W.
- Abstract
Eighty nursery school children were randomly divided into four groups of 20 and given a serial short-term memory task in which difficult-to-label stimuli were used. Three experimental groups were provided with labels for the stimuli. Of these, one group overtly pronounced the labels and rehearsed them during the task, one group merely pronounced the labels overtly, and one group was instructed to say the labels covertly. A control group received no labels for the stimuli. Rehearsal of the labels was found to facilitate recall performance on early serial items, and overt labeling facilitated recall on the last serial item. Covert labeling did not facilitate recall. The results supported the hypothesis that qualitatively different processing strategies determine primacy and recency effects. Current theories of the role of verbalizing in children's memory performance are discussed. (Author/MS)
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- 1968
20. Luria's Model of the Verbal Control of Behavior. Study F: Motivational and Control in the Development of Language Functions, D. Birch.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Beiswenger, Hugo
- Abstract
A. R. Luria, in his conception of the verbal control of behavior, regards four fundamental and distinctive functional attributes of the human speech system as making up a signaling system that humans alone possess: (1) the nominative role of language, (2) the generalizing or semantic role, (3) the communicative role, and (4) the role of regulating, directing, or controlling sequential behavior. Prior to the time a child learns to speak, his signaling system is nonverbal and is generated by the physical attributes of the surrounding environment. Luria contends that as the individual matures, the two signaling systems, verbal and nonverbal, work more closely together. He states that the verbal system, both in its communicative and regulative aspects, makes possible novel and flexible behavior without the tedious conditioning necessary for animal learning. Luria views speech as being formed through a series of transformations (substages) rather than through quantitative increases in such things as vocabulary and grammatical rules. In order to test Luria's theory, an experiment involving discrimination was administered to 32 children between the ages of 41 and 78 months. The results generally supported the hypotheses. (WD)
- Published
- 1968
21. Linguistic and Psychological Factors in the Speech Regulation of Behavior in Very Young Children.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Beiswenger, Hugo A.
- Abstract
This dissertation examines the thesis that it is the human language system which largely makes possible the human capacity for modifiability of responses called "intelligent" and "adaptive" modes of interaction with the environment. Chapter titles are (1) A Process View of Human Behavior, (2) Aspects of the Multi-Dimensional Nature of Cognitive Processes in the Very Young Child, (3) Linguistic Theory as a Model of Language Perception and Learning, (4) The Structure of Linguistically Initiated Behavioral Acts, (5) The Relationship of the Comprehension of Sentences to Their Complexity, (6) An Experimental Study of Linguistic and Other Psychological Factors in the R-EGULATION OF Behavior in Very Young Children, and (7) Discussion of Results. The author concludes that perceptual or attentional processes which involve expressions of orienting activity should be studied in regard to ontogenetic development and its relationship to the verbal system of preschool children. (MS)
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- 1968
22. Cognitive and Linguistic Deficits in Psychotic Children. Study M: Development of Selective Attention Abilities.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Hagen, John W.
- Abstract
Tasks involving several areas of cognitive functioning were given to 10 psychotic children and 30 normal children. Comparisons of performance were made between the two groups and also within the psychotic group. The dimension for differentiation was the psychotic children's varying degree of language facility. The psychotic children were classified into three language facility groups: functional, semifunctional, and nonfunctional. The cognitive abilities tested for were short term memory, discrimination, generalization, transposition, and discrimination reversal. They were chosen because they were significantly language-related or language-mediated. The results of performance on the cognitive functioning tasks showed that (1) the normal children performed consistently better than the psychotic children, (2) the language facility groups of the psychotic children differentiated their performance on the memory task involving a verbal cue, with the functional group performing best, and (3) certain trends in the data suggest a relationship between language functioning and cognitive performance on the tasks investigated. (WD)
- Published
- 1967
23. Tangent to Experimental Techniques of Verbal Control.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Bilodeau, Ina McD
- Abstract
This paper is a critical comment and reaction to a 1965 article by G. A. Miller entitled "Some Preliminaries to Psycholinguistics." The subject matter is verbal control of behavior. Seven specific aspects of the Miller address are discussed. (WD)
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- 1965
24. The Development of Interrogative Structures in Children's Speech.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Bellugi, Ursula
- Abstract
The verbal behavior of three children was sampled. The samples were analyzed to obtain a picture of three stages of the children's language development, specifically the interrogative structures. Each stage was about 4- or 5-months long, starting at the 18th to 28th month, depending upon the child's level of linguistic ability. The interrogative structures of primary interest were (1) intonation patterns, (2) auxiliary inversion, (3) negation, (4) WH word (what, who, why, etc.) placement, and (5) tag questions. At stage one, inflections, auxiliaries, articles, and most pronouns were absent. The child used intonation to mark a question. There were no yes-or-no questions and only a few WH questions. There were no tag questions. The child at this stage did not appear to understand the interrogatory structure when he heard it. At stage two, articles, pronouns, and negative preverb forms appeared. Auxiliaries were still not present, nor were tag questions. Stage three included the emergence of the use of auxiliaries, auxiliary inversion, and the do transformation. Inversion and transformation were found in yes-or-no questions but were absent in WH questions. Tag questions were still absent, but the children understood and responded well to questions. An appendix of sample questions obtained from the subjects at each stage is included. (WD)
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- 1965
25. Subjects' Hypotheses, Experimental Instructions and Autonomic 'Conditioning'.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Eriksen, Charles W.
- Abstract
Research on learning and conditioning suggests that verbal response modification does not occur in the absence of the subject's ability to define verbally (1) the response-reinforcement relationships and (2) his intention to change his behavior in the direction of reinforcement. This seems to be true for operant conditioning of verbal behavior, operant conditioning of skeletal nonverbal responses, and perceptual learning of correlated cues. Research in the area of conditioning of autonomic responses shows consistently that subjects who are aware of the stimulus-negative reinforcement condition manifest greater autonomic response conditioning than subjects who are not aware of the experimental conditions. (WD)
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- 1965
26. Grammatical Development in Russian-Speaking Children.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Slobin, Dan I.
- Abstract
A contribution to the debate on innate factors in children's language acquisition is rendered by cross-linguistic comparisons of children's languages. Russian, for example, is sufficiently different from English to serve as a useful contrast. Early syntactic development is very much the same in both languages. A small class of "pivot words" and a larger open class of words are used first. Word order is quite inflexible at each of the early stages of syntactic development. Two-word sentences appear at about 1:8 (1 year, 8 months); three- or four-word sentences appear at about 1:10. Morphological markers enter with the three- and four-word sentences. The learning of morphology goes on longer than the learning of syntactic patterns. A major Russian work on language development contends that the Russian child does not master his morphology until several years beyond the age at which the American child completes his primary grammatical learning. This factor suggests that it may be more difficult to learn to speak one language natively than another, although in both, basic learning is accomplished rapidly. (WD)
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- 1965
27. Development of the Prosodic Features of Infants' Vocalizing.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development., Lane, Harlan, and Sheppard, William
- Abstract
Traditional research methods of recording infant verbal behavior, namely, descriptions by a single observer transcribing the utterances of a single infant in a naturalistic setting, have been inadequate to provide data necessary for modern linguistic analyses. The Center for Research on Language and Language Behavior has undertaken to correct this inadequacy. The Center collected permanent, complete, and continuous records of all vocalizations of two infants during their first five months of life. This data was then processed by new electro-acoustic techniques. In processing one hundred and eight 95-second vocal behavior samples, the computer determined (1) the number of utterances, (2) the duration of each utterance, and (3) the mean and standard deviation of the fundamental frequency and amplitude of each utterance. Further statistical analyses are now in progress. (WD)
- Published
- 1965
28. A Distinctive Features Analysis of Pre-Linguistic Infant Vocalizations.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Ringwall, Egan A.
- Abstract
A research project was aimed at measuring the relationship between infant vocalizations and linguistic development and determining the feasibility of using infant vocalizations as a predictor of later psychological and intellectual status. However, a method was needed to analyze the vocalizations of infants. This report describes a method used to analyze the vocal behavior of infants in their prelinguistic stage, from birth to 4 months. The method was based on the "distinctive features" concept. Eight distinctive features of infant vocalization were coded by observers. This data yielded information on the quality and frequency of infant vocal behavior and provided a measure of individual differences between prelinguistic infants. Data have been collected on forty 3-day-old infants. This eight-feature coding scheme has proven to be reliable. (WD)
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- 1965
29. The Development of Language Functions. Report Number 8, Development of Language Functions: A Research Program Project.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Riegel, Klaus F.
- Abstract
This document includes 10 articles dealing with five specific areas of language development. Two articles and a commentary cover each area. Resumes of the articles have been assigned the following numbers: memory functions (PS 001 487 and PS 001 488), associations and verbal habits (PS 001 489 and PS 001 490), language perception and discrimination (PS 001 491 and PS 001 492), verbal structures (PS 001 493 and PS 001 494), and verbal control PS 001 495 and PS 001 496). (WD)
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- 1965
30. Extension of a Theory of Predictive Behavior to Immediate Recall by Preschool Children.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Bogartz, Richard S.
- Abstract
This paper is concerned with memory functions in sequentially structured behavior. Twenty-five 4- and 5-year-old preschool children participated in a prediction experiment in which a stack of cards (each card alternately having a patch of red or green tape on it) was displayed to the child. The child was presented with a card and asked to predict the color on the next card. Two interval lengths, a long and a short, were used between presentation and prediction. The subject's performance, it was thought, was affected by (1) memory of each trial, (2) effects of the previous response, (3) lagging of attention, (4) guessing, and (5) the variation in interval length. The results from 100 trials indicated that the probability of an error, given a correct response on the previous trial, is greater following the long interval than following the short. It was also found that the probability of an error, given a correct response, is less than or equal to both the probability of a correct response, given an error, and the probability of an error, given an error. The theoretical basis of this task is being used to develop a recall task similar in form to the prediction task. (WD)
- Published
- 1965
31. Age and Memory as Factors in Problem Solving.
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Weir, Morton W.
- Abstract
In a 1964 investigation of the effects of age and memory on problem solving, using subjects from age three to age nineteen, it was found that the youngest and oldest subjects performed a three-choice probabilistic task significantly different from the "middle-age" children (7 to 9 years old). The three-choice task was an apparatus with a signal light, three buttons, and a container into which marbles were dispensed for "correct" responses. Only one button was set up to release a marble, and even it was on a partial reinforcement schedule. The younger and older subjects tended to maximize their choice of the "pay-off" button. The middle-age children tended to respond in simple patterns regardless of the fact that such patterns did not increase the pay-off. It was thought that this result interfered with their memory in regard to which button was paying off. A later study, in which a memory aid was used for half of the subjects, was conducted. It was found that the younger and older subjects performed about the same as before, regardless of the existence of the memory aid. The 7- and 9-year-olds who used the aid performed significantly better than those who did not. A third study, similar to the previous studies except that four different reinforcement schedules were used, indicated that responses become more complex with age. (WD)
- Published
- 1965
32. COMMUNICATION OF PRONOMINAL REFERENTS IN AMBIGUOUS ENGLISH SENTENCES FOR CHILDREN AND ADULTS.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and CHAI, DAVID T.
- Abstract
THIS RESEARCH STUDY WAS BASED ON THE ASSUMPTION THAT THE TECHNIQUE OF PSYCHOLINGUISTIC EXPERIMENTATION, AS WELL AS FORMAL ANALYSIS, CAN BE APPLIED TO DISCOVER SOME VARIABLES WHICH ALLOW THE HUMAN TO RESOLVE AMBIGUOUS SENTENCES. THE PROBLEM OF AMBIGUITY WAS CONFINED TO SITUATIONS IN WHICH A KEY PRONOUN IN A SENTENCE HAS MORE THAN ONE POSSIBLE ANTECEDENT. THE OBJECTIVE WAS TO DISCOVER SOME PARAMETERS THAT CONTROL THE ABILITY TO RESOLVE AMBIGUOUS PRONOMINAL REFERENCE IN DIFFERENT AGE GROUPS. THE EXPERIMENT INVOLVED A SET OF 176 SENTENCES, EACH OF WHICH CONTAINED PRONOUNS WITH AMBIGUOUS ANTECEDENTS. THE EXPERIMENTAL SUBJECTS--FIFTH, SEVENTH, AND EIGHTH GRADE CHILDREN, AND COLLEGE SOPHOMORES--JUDGED THE MOST APPROPRIATE REFERENT IN EACH SENTENCE. RESULTS FROM THE SOPHOMORE GROUP CONCLUSIVELY DEMONSTRATED THAT SUBJECTS COULD RESOLVE AN AMBIGUITY IN A SENTENCE BY REDUCING THE MEANING OF A KEY WORD FROM TWO TO ONE. EIGHTH GRADE SUBJECTS DEMONSTRATED THEY COULD LARGELY RESOLVE THE PRONOMINAL REFERENT WHEN REAL VERBS WERE USED (AS OPPOSED TO NONSENSE VERBS). RESULTS FROM THE SEVENTH GRADE SUBJECTS SHOWED A FURTHER DEGENERATION WITH RESPECT TO THE RESPONSES OF THE EIGHTH GRADERS. IN GENERAL THE FIFTH GRADE SUBJECTS WERE NOT ABLE TO RESOLVE THE PRONOMINAL AMBIGUITIES. THIS REPORT INCLUDES AN EXTENSIVE BIBLIOGRAPHY, THE TEST SENTENCES, RESPONSE MATRICES, AND AN "IDEAL GROUP" CHART. (AM)
- Published
- 1967
33. Post-Crisis Growth in Developing Countries: A Special Report of the Commission on Growth and Development on the Implications of the 2008 Financial Crisis
- Author
-
Commission on Growth and Development
- Published
- 2010
34. The Recall of High and Low Meaningful Sentences Generated from the Michigan Restricted Association Norms.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development., Riegel, Klaus F., and Feldman, Carol F.
- Abstract
Eight sentences with high associative connections between their major elements (hi-m sentences) were generated from the Michigan Restricted Association Norms (Riegel, 1965a, b). Eight additional sentences with no or low association connections (lo-m sentences) were derived from the hi-m sentences by a scrambling procedure. All sentences were of the form subject-verb-object or subject-verb-location, and were presented to eight male and eight female undergraduates in a learning task. Hi-m sentences were recalled significantly more often than lo-m sentences. The interaction, but not the differences, between the first and second trials were significant. There was an increase in the recall scores from trial to trial for the hi-m sentences but a decrease for the lo-m sentences. Generally, the results confirmed that it is possible to construct sentences with predictable recall scores on the basis of restricted and free association norms. This paper comprises a report in "Development of Language Functions, A Research Program-Project (Study B: Developmental Studies in Semantics)." (Author/DO)
35. Hepatitis C Virus Load Is Associated with Human Immunodeficiency Virus Type 1 Disease Progression in Hemophiliacs
- Author
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Hemophilia Growth and Development Study, Daar, Eric S., Lynn, Henry, Donfield, Sharyne, Gomperts, Edward, O'Brien, Stephen J., Hilgartner, Margaret W., Hoots, W. Keith, Chernoff, David, Arkin, Steven, Wong, W.-Y., and Winkler, Cheryl A.
- Published
- 2001
36. The Role of Seafood Consumption in Child Growth and Development
- Author
-
National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Food and Nutrition Board, Committee on the Role of Seafood Consumption on Child Growth and Development, National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Food and Nutrition Board, and Committee on the Role of Seafood Consumption on Child Growth and Development
- Subjects
- Pregnancy--Nutritional aspects--United States, Seafood, Children--Nutrition--United States, Seafood--Health aspects--United States, Seafood--Nutritional aspects--United States, Pregnant women, Child development
- Abstract
Seafood--including marine and freshwater fish, mollusks, and crustaceans--is a healthy food choice, but it can also contain contaminants. It is currently unclear how much seafood children or pregnant and lactating women are consuming, and what impact seafood consumption is having on children's growth and development. The U.S. Department of Health and Human Services, the U.S. Department of Agriculture, the U.S. Environmental Protection Agency, and the National Oceanic and Atmospheric Administration tasked the National Academies of Sciences, Engineering, and Medicine with convening an expert committee to examine associations between seafood intake for children, adolescents, and pregnant and lactating women and child growth and development. The committee also evaluated when to conduct risk-benefit analyses (RBAs), while considering contextual factors such as equity, diversity, inclusion, and access to health care, and explored how these factors might impact RBAs.
- Published
- 2024
37. Journal of a medical and population genetic survey expedition of the research vessel Alpha Helix to the Banks and Torres Islands of the New Hebrides, Southern Islands of the British Solomon Islands protectorate, and Pingelap Atoll, Eastern Caroline Islands : September 8, 1972 to November 26, 1972 /
- Author
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Gajdusek, D. Carleton (Daniel Carleton), 1923, National Institute of Neurological and Communicative Disorders and Stroke. Study of Child Growth and Development and Disease Patterns in Primitive Cultures, NIH Library (archive.org), Gajdusek, D. Carleton (Daniel Carleton), 1923, and National Institute of Neurological and Communicative Disorders and Stroke. Study of Child Growth and Development and Disease Patterns in Primitive Cultures
- Subjects
(Daniel Carleton) ,1923- ,Gajdusek, D. Carleton ,Genetics, Population ,Health Surveys ,History ,Pacific Islands ,Personal narratives ,population genetics - Published
- 1985
38. Incidence of focal white matter lesions in a population of hemophiliac children and their normal siblings
- Author
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Nelson Jr., M. D., Wilson, D. A., Kisker, C. T., Evatt, B. L., Fenstermacher, M. J., Lynn, H. S., Donfield, S. M., Maeder, M. A., and Hemophilia Growth and Development Study
- Published
- 2000
- Full Text
- View/download PDF
39. Development of Language: Suggestions for a Verbal Fallout Model. Report Number 4, Development of Language Function. A Research Program-Project. Study B: Developmental Studies in Semantics.
- Author
-
Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Riegel, Klaus F.
- Abstract
Language acquisition is a quantifiable system with the sum total of verbal inputs and outputs increasing with the age of the subject. Increases in vocabulary are positively accelerated during developmental years and become negatively accelerated or zero during adult years. Thus, older people have available a larger active and passive vocabulary. To check the validity of the Bousfield and Sedgewick equations which predict vocabulary acquisition, a test was designed which required subjects of different ages to write all the words that occurred to them in a given interval of time. Contrary to expectations, older subjects did not show greater fluency--a finding which may reflect response time more than memory. Future research should focus on the factors that prevent individuals from making the most efficient use of stored information. The appendixes include an explanation of statistical methods and graphic summaries of test results. (EMH)
- Published
- 1965
40. Word Associations as Related to Children's Verbal Habits.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Palermo, David S.
- Abstract
Free-association norms for 200 words were obtained in 1964 from the responses of 500 subjects in each of grades four through eight, 10, and 12 and from 1,000 college students. An analysis of this normative data revealed that (1) the frequency of occurrence of the most popular associative responses to stimulus words increases with the age of the subject, (2) the number of different responses to a word decreases with the age of the subject, (3) the response words themselves undergo about a 50 percent change from the fourth grade to college, (4) contrast or opposite responses increase with age, and (5) paradigmatic responses also increase with the age of the subject. Thus, word-association characteristics vary importantly between children and adults. The influence of the associative strength of words on different verbal learning tasks has been investigated. Such an influence has been demonstrated for paired-associate learning, clustering in free recall, associative generalization, and mediated generalization. Normative word association data have also been collected for children in grades one through four. Analysis of these data shows the same trends as observed in the norms discussed for the larger population. (WD)
- Published
- 1965
41. Free-Association Norms and Associative Structure.
- Author
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Michigan Univ., Ann Arbor. Center for Human Growth and Development. and Bilodeau, Edward A.
- Abstract
This paper discusses the theory and presents examples of free-association norms. Examples from several categories of free-association data are given. Their use in experiments on cultural characteristics of the associative structures of words are also explained. A graph of the relationship between primary and secondary associations and tables of associations and probability hierarchies are included. These tables are explained in the text of the paper and illustrated in the appendix. A bibliography is also included. (WD)
- Published
- 1965
42. Book review
- Author
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Department of Anthropology, Center for Human Growth and Development, University of Michigan, Ann Arbor, MI, Department of Anthropology Center for Human Growth and Development University of Michigan, Ann Arbor, MI, Frisancho, Roberto, Department of Anthropology, Center for Human Growth and Development, University of Michigan, Ann Arbor, MI, Department of Anthropology Center for Human Growth and Development University of Michigan, Ann Arbor, MI, and Frisancho, Roberto
- Abstract
No abstract.
- Published
- 2011
43. Motor development in 9-month-old infants in relation to cultural differences and iron status
- Author
-
Center for Human Growth and Development, School of Kinesiology, University of Michigan, 300 N. Ingalls, 10th Floor, Ann Arbor, MI 48109-5406 ; Center for Human Growth and Development, School of Kinesiology, University of Michigan, 300 N. Ingalls, 10th Floor, Ann Arbor, MI 48109-5406., Center for Human Growth and Development, School of Kinesiology, University of Michigan, 300 N. Ingalls, 10th Floor, Ann Arbor, MI 48109-5406, Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, Peking First University Hospital, Beijing, China, Noguchi University of Ghana Medical School, Accra, Ghana, Department of Psychiatry and Behavioral Neuroscience, Wayne State University, Detroit, MI, Angulo-Barroso, Rosa M., Schapiro, Lauren, Liang, Weilang, Rodrigues, Onike, Shafir, Tal, Kaciroti, Niko, Jacobson, Sandra W., Lozoff, Betsy, Center for Human Growth and Development, School of Kinesiology, University of Michigan, 300 N. Ingalls, 10th Floor, Ann Arbor, MI 48109-5406 ; Center for Human Growth and Development, School of Kinesiology, University of Michigan, 300 N. Ingalls, 10th Floor, Ann Arbor, MI 48109-5406., Center for Human Growth and Development, School of Kinesiology, University of Michigan, 300 N. Ingalls, 10th Floor, Ann Arbor, MI 48109-5406, Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, Peking First University Hospital, Beijing, China, Noguchi University of Ghana Medical School, Accra, Ghana, Department of Psychiatry and Behavioral Neuroscience, Wayne State University, Detroit, MI, Angulo-Barroso, Rosa M., Schapiro, Lauren, Liang, Weilang, Rodrigues, Onike, Shafir, Tal, Kaciroti, Niko, Jacobson, Sandra W., and Lozoff, Betsy
- Abstract
Motor development, which allows infants to explore their environment, promoting cognitive, social, and perceptual development, can be influenced by cultural practices and nutritional factors, such as iron deficiency. This study compared fine and gross motor development in 209 9-month-old infants from urban areas of China, Ghana, and USA (African-Americans) and considered effects of iron status. Iron deficiency anemia was most common in the Ghana sample (55%) followed by USA and China samples. Controlling for iron status, Ghanaian infants displayed precocity in gross motor development and most fine-motor reach-and-grasp tasks. US African-Americans performed the poorest in all tasks except bimanual coordination and the large ball. Controlling for cultural site, iron status showed linear trends for gross motor milestones and fine motor skills with small objects. Our findings add to the sparse literature on infant fine motor development across cultures. The results also indicate the need to consider nutritional factors when examining cultural differences in infant development. ?? 2010 Wiley Periodicals, Inc. Dev Psychobiol 53:196???210, 2011
- Published
- 2011
44. Advanced Tooth Emergence in Negro Individuals
- Author
-
Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48104, USA, Michigan Department of Public Health, Lansing, Michigan, Center for Disease Control, Atlanta, Georgia, Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48104, USA, Garn, Stanley M., Wertheimer, Fred, Sandusky, Sam, Mccann, Mary, Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48104, USA, Michigan Department of Public Health, Lansing, Michigan, Center for Disease Control, Atlanta, Georgia, Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48104, USA, Garn, Stanley M., Wertheimer, Fred, Sandusky, Sam, and Mccann, Mary
- Published
- 2010
45. Relative Magnitudes of Crown Size Reduction and Body Size Reduction in 47-Trisomy G
- Author
-
Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48104, USA, Department of Oral Pathology, Tufts University, Boston, Massachusetts, Plymouth State Home & Training School, Northville, Michigan, Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48104, USA, Plymouth State Home & Training School, Northville, Michigan, Department of Oral Pathology, Tufts University, Boston, Massachusetts, Garn, Stanley M., Cohen, M., Gall, John, Nagy, Jerrold, Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48104, USA, Department of Oral Pathology, Tufts University, Boston, Massachusetts, Plymouth State Home & Training School, Northville, Michigan, Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48104, USA, Plymouth State Home & Training School, Northville, Michigan, Department of Oral Pathology, Tufts University, Boston, Massachusetts, Garn, Stanley M., Cohen, M., Gall, John, and Nagy, Jerrold
- Published
- 2010
46. Adaptation of the masseter and temporalis muscles following alteration in length, with or without surgical detachment
- Author
-
Department of Physiology University of Michigan, Ann Arbor, Michigan 48109 ; The Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109, Department of Anatomy, University of Michigan, Ann Arbor, Michigan 48109 ; The Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109, Department of Physiology University of Michigan, Ann Arbor, Michigan 48109, Maxwell, Leo C., Carlson, David S., McNamara, James A. Jr., Faulkner, John A., Department of Physiology University of Michigan, Ann Arbor, Michigan 48109 ; The Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109, Department of Anatomy, University of Michigan, Ann Arbor, Michigan 48109 ; The Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109, Department of Physiology University of Michigan, Ann Arbor, Michigan 48109, Maxwell, Leo C., Carlson, David S., McNamara, James A. Jr., and Faulkner, John A.
- Abstract
Histochemical properties, muscle fiber cross-sectional area, muscle fiber length, and the oxidative capacity of masticatory muscles of female rhesus monkeys were assessed following alteration in functional length by an intraoral appliance or by detachment of the muscle. Experimental groups received the appliance only (A); the appliance and subsequent detachment of the masseter (AD); the appliance and detached masseter, but with surgical reattachment of the masseter to the pterygomasseteric sling (ADR); no appliance, but detachment and reattachment of masseter (DR); or an appliance which was removed after 24 weeks to study posttreatment responses (PT). Animals were sacrificed and the muscles were studied at intervals from 4 to 48 weeks after initiation of the experimental period. The results of these studies led to the following conclusions: (1) Stretching the masseter and temporalis muscles within physiological limits did not significantly alter the proportion of fiber types, although oxidative capacity of the fibers was reduced. (2) Fibers with “intermediate” myofibrillar AT-Pase activity were no more prevalent in experimental than control muscles. (3) The cross-sectional area of Type I fibers of masseter muscles decreased following some experimental procedures, indicating that recruitment of these fibers is the most sensitive to altered jaw function. (4) Minimal alteration of muscle capillarity was induced by any of the experimental procedures. (5) The lengths of masseter muscle fibers in Group PT and of temporalis muscle fibers in groups AD and ADR were greater than in control animals.
- Published
- 2007
47. Developmental components of resting ventilation among high- and low-altitude Andean children and adults
- Author
-
University of Michigan, Ann Arbor, Michigan 48109 ; Center for Human Growth and Development, 300 N. Ingalls Bldg., University of Michigan, Ann Arbor, MI 48109-0406., Undergraduate Participants in the NIH-Fogarty Minority International Research Training Program of the Center for Human Growth and Development of the University of Michigan, Ann Arbor, Michigan 48109, Instituto Boliviano de BiologÍa de Altura, La Paz, Bolivia, Frisancho, A. Roberto, Juliao, Patricia C., Barcelona, Veronica, Kudyba, Carmela E., Amayo, Glenda, Davenport, Grecia, Knowles, Alicia, Sanchez, Dani, Villena, Mercedes, Vargas, Enrique, Soria, Rudy, University of Michigan, Ann Arbor, Michigan 48109 ; Center for Human Growth and Development, 300 N. Ingalls Bldg., University of Michigan, Ann Arbor, MI 48109-0406., Undergraduate Participants in the NIH-Fogarty Minority International Research Training Program of the Center for Human Growth and Development of the University of Michigan, Ann Arbor, Michigan 48109, Instituto Boliviano de BiologÍa de Altura, La Paz, Bolivia, Frisancho, A. Roberto, Juliao, Patricia C., Barcelona, Veronica, Kudyba, Carmela E., Amayo, Glenda, Davenport, Grecia, Knowles, Alicia, Sanchez, Dani, Villena, Mercedes, Vargas, Enrique, and Soria, Rudy
- Abstract
This paper evaluates the age-associated changes of resting ventilation of 115 high- and low-altitude Aymara subjects, of whom 61 were from the rural Aymara village of Ventilla situated at an average altitude of 4,200 m and 54 from the rural village of Caranavi situated at an average altitude of 900 m. Comparison of the age patterns of resting ventilation suggests the following conclusions: 1) the resting ventilation (ml/kg/min) of high-altitude natives is markedly higher than that of low-altitude natives; 2) the age decline of ventilation is similar in both lowlanders and highlanders, but the starting point and therefore the age decline are much higher at high altitude; 3) the resting ventilation that characterizes high-altitude Andean natives is developmentally expressed in the same manner as it is at low altitude; and 4) the resting ventilation (ml/kg/min) of Aymara high-altitude natives is between 40–80% lower than that of Tibetans. Am J Phys Anthropol 109:295–301, 1999. © 1999 Wiley-Liss, Inc.
- Published
- 2006
48. Lack of???acid reversal??? of myofibrillar adenosine triphosphatase in masticatory muscle fibres of rhesus monkeys
- Author
-
Departments of Physiology and Anatomy, The University of Michigan, 48709, Ann Arbor, Michigan, USA; The Center for Human Growth and Development, The University of Michigan, 48709, Ann Arbor, Michigan, USA; Department of Physiology, The University of Texas, Health Science Center at San Antonio, 7703 Floyd Curl Drive, 78284, San Antonio, Texas, USA, Departments of Physiology and Anatomy, The University of Michigan, 48709, Ann Arbor, Michigan, USA; The Center for Human Growth and Development, The University of Michigan, 48709, Ann Arbor, Michigan, USA, Ann Arbor, Maxwell, Leo C., Carlson, David S., Brangwyn, Carole, Departments of Physiology and Anatomy, The University of Michigan, 48709, Ann Arbor, Michigan, USA; The Center for Human Growth and Development, The University of Michigan, 48709, Ann Arbor, Michigan, USA; Department of Physiology, The University of Texas, Health Science Center at San Antonio, 7703 Floyd Curl Drive, 78284, San Antonio, Texas, USA, Departments of Physiology and Anatomy, The University of Michigan, 48709, Ann Arbor, Michigan, USA; The Center for Human Growth and Development, The University of Michigan, 48709, Ann Arbor, Michigan, USA, Ann Arbor, Maxwell, Leo C., Carlson, David S., and Brangwyn, Carole
- Abstract
Myofibrillar adenosine triphosphatase (ATPase) activity was demonstrated in sections of masseter and temporalis muscles and of selected limb muscles of adult rhesus monkeys. Incubations were performed either with no pre-treatment or after prior incubation in alkaline media (pH 10.2???10.4) or acidic media (pH 3.8???4.6). Without pre-treatment, fibres having high or low ATPase activity were observed in limb and masticatory muscles. Following alkaline pre-incubation the difference between high and low ATPase of limb muscle fibres is accentuated, whereas pre-incubation in acidic media (pH 4.3) results in inhibition of high and potentiation of low ATPase activities (???acid reversal???). While pre-incubation of masticatory muscle sections at pH 10.2 accentuates differences in ATPase activity, pre-incubation at pH 10.4 abolishes ATPase activity. In contrast, masticatory muscle fibres showed no reversal of ATPase activity following acidic pre-incubation (pH 4.3). Pre-incubation at pH 3.8 abolished the ATPase activity of both limb and masticatory muscle fibres. The biochemical basis for the differences in ATPase histochemistry between masticatory and limb muscles is not known.
- Published
- 2006
49. Relationship of serum cholesterol and truncal body fat distribution among Mexican Americans is accentuated by obesity
- Author
-
Center for Human Growth and Development, and Department of Anthropology, The University of Michigan, Ann Arbor, Michigan 48109 ; Center for Human Growth and Development, University of Michigan, 300 N. Ingalls, Ann Arbor, MI 48109-0406, Center for Human Growth and Development, and Department of Anthropology, The University of Michigan, Ann Arbor, Michigan 48109, Frisancho, A. Roberto, Smith, Shelley L., Albalak, Rachel, Center for Human Growth and Development, and Department of Anthropology, The University of Michigan, Ann Arbor, Michigan 48109 ; Center for Human Growth and Development, University of Michigan, 300 N. Ingalls, Ann Arbor, MI 48109-0406, Center for Human Growth and Development, and Department of Anthropology, The University of Michigan, Ann Arbor, Michigan 48109, Frisancho, A. Roberto, Smith, Shelley L., and Albalak, Rachel
- Abstract
The relationship of body fat distribution to serum cholesterol levels was evaluated in a sample of 3,040 Mexican Americans 18-74 years of age from the Hispanic Health and Nutrition Examination Survey (HHANES) conducted from 1982-1984. Fat distribution was determined by the ratio of trunk to extremity skinfold thicknesses, while the sum of skinfold thicknesses was used as an indicator of total body fat. Results of this study indicate that: 1) Mexican Americans are significantly fatter and have a higher trunk/extremity skinfold ratio than U.S. standards; 2) despite their higher level of total body fat and truncal fat, Mexican Americans have lower serum cholesterol levels than U.S. standards; 3) Mexican American males at the same percentile level of fatness or trunk/extremity skinfold ratio have significantly higher serum cholesterols than females, despite the fact that females have higher absolute values of fat and truncal fat than males; 4) among Mexican American males the association between truncal fat distribution and hypercholesteremia increases with level of fatness. In other words, in Mexican American males the association of truncal fat distribution with hypercholesteremia is accentuated by obesity. © 1994 Wiley-Liss, Inc.
- Published
- 2006
50. Frog lysozyme. I. Its identification, occurrence as isozymes, and quantitative distribution in tissues of the leopard frog, Rana pipiens Contribution No. 64 from the Amphibian Facility., The animals used in this study were maintained in facilities that are fully accredited by the American Association for Accreditation of Laboratory Animal Care (AAALAC).
- Author
-
Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 ; Adapted, in part, from dissertations submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy, The University of Michigan., Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109, Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 ; Division of Biological Sciences, The University of Michigan, Ann Arbor, Michigan 48109, Ostrovsky, David S., Snyder, John A., Iwata, Takuzo, Izaka, Ken-Ichi, Maglott, Donna S., Nace, George W., Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 ; Adapted, in part, from dissertations submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy, The University of Michigan., Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109, Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 ; Division of Biological Sciences, The University of Michigan, Ann Arbor, Michigan 48109, Ostrovsky, David S., Snyder, John A., Iwata, Takuzo, Izaka, Ken-Ichi, Maglott, Donna S., and Nace, George W.
- Abstract
In the course of examining the etiology of the Luck?? renal adenocarcinoma of the frog, Rana pipiens, it was found that organs of the normal adult contain bacteriolytic enzymes. These enzymes all satisfied the six criteria for the identification of lysozymes and at least eight forms were separable by polyacrylamide gel electrophoresis. Their qualitative and quantitative distribution was organ-specific. All eight isozymes were found in normal kidney, while liver and spleen contained seven forms; skin, six; ovarian egg, five; and serum, two. In quantitative assays using a radial diffusion test, spleen had the greatest lysozyme concentration, followed in descending order by kidney, liver, skin, and ovary. Serum contained very low amounts. In terms of enzyme activity per animal, ovary was the highest ranking organ. As such a large number of lysozyme isozymes has not been reported in any other organism, their origins and functions are considered in the context of their presence in an ectotherm.
- Published
- 2006
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