629 results on '"Grimsgaard AS"'
Search Results
2. Advancing a new model of collaborative practice: a decade of Whole Health interprofessional education across Veterans Health Administration
- Author
-
Liao, Theresa H., Rindfleisch, J. Adam, Howard, Kelly Peyton, Castellani, Marc, and Noyes, Sara Grimsgaard
- Published
- 2024
- Full Text
- View/download PDF
3. Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level: findings from the MORGAM project
- Author
-
Di Castelnuovo, Augusto, Bonaccio, Marialaura, Costanzo, Simona, McElduff, Patrick, Linneberg, Allen, Salomaa, Veikko, Männistö, Satu, Ferrières, Jean, Dallongeville, Jean, Thorand, Barbara, Brenner, Hermann, Ferrario, Marco, Veronesi, Giovanni, Tamosiunas, Abdonas, Grimsgaard, Sameline, Drygas, Wojciech, Malyutina, Sofia, Söderberg, Stefan, Nordendahl, Maria, Kee, Frank, Grassi, Guido, Dabboura, Salim, Borchini, Rossana, Westermann, Dirk, Schrage, Benedikt, Zeller, Tanja, Kuulasmaa, Kari, Blankenberg, Stefan, Donati, Maria Benedetta, Iacoviello, Licia, and de Gaetano, Giovanni
- Published
- 2023
- Full Text
- View/download PDF
4. Comparing associations of handgrip strength and chair stand performance with all-cause mortality—implications for defining probable sarcopenia: the Tromsø Study 2015–2020
- Author
-
Jonas Johansson, Sameline Grimsgaard, Bjørn Heine Strand, Avan A. Sayer, and Rachel Cooper
- Subjects
Handgrip strength ,Chair stand performance ,All-cause mortality ,Sarcopenia ,Medicine - Abstract
Abstract Background Widely adopted criteria suggest using either low handgrip strength or poor chair stand performance to identify probable sarcopenia. However, there are limited direct comparisons of these measures in relation to important clinical endpoints. We aimed to compare associations between these two measures of probable sarcopenia and all-cause mortality. Methods Analyses included 7838 community-dwelling participants (55% women) aged 40–84 years from the seventh survey of the Tromsø Study (2015–2016), with handgrip strength assessed using a Jamar + Digital Dynamometer and a five-repetition chair stand test (5-CST) also undertaken. We generated sex-specific T-scores and categorised these as “not low”, “low”, and “very low” handgrip strength or 5-CST performance. Cox Proportional Hazard regression models were used to investigate associations between these two categorised performance scores and time to death (up to November 2020 ascertained from the Norwegian Cause of Death registry), adjusted for potential confounders including lifestyle factors and specific diseases. Results A total of 233 deaths occurred (median follow-up 4.7 years) with 1- and 5-year mortality rates at 3.1 (95% confidence interval [CI] 2.1, 4.6) and 6.3 (95% CI 5.5, 7.2) per 1000 person-years, respectively. There was poor agreement between the handgrip strength and 5-CST categories for men (Cohen’s kappa [κ] = 0.19) or women (κ = 0.20). Fully adjusted models including handgrip strength and 5-CST performance mutually adjusted for each other, showed higher mortality rates among participants with low (hazard ratio [HR] 1.22, 95% CI 0.87, 1.71) and very low (HR 1.68, 95% CI 1.02, 2.75) handgrip strength compared with the not low category. Similar associations, although stronger, were seen for low (HR 1.88, 95% CI 1.38, 2.56) and very low (HR 2.64, 95% CI 1.73, 4.03) 5-CST performance compared with the not low category. Conclusions We found poor agreement between T-score categories for handgrip strength and 5-CST performance and independent associations with mortality. Our findings suggest that these tests identify different people at risk when case-finding probable sarcopenia. As discussions on an international consensus for sarcopenia definitions proceed, testing both handgrip strength and chair stand performance should be recommended rather than viewing these as interchangeable assessments.
- Published
- 2023
- Full Text
- View/download PDF
5. Comparing associations of handgrip strength and chair stand performance with all-cause mortality—implications for defining probable sarcopenia: the Tromsø Study 2015–2020
- Author
-
Johansson, Jonas, Grimsgaard, Sameline, Strand, Bjørn Heine, Sayer, Avan A., and Cooper, Rachel
- Published
- 2023
- Full Text
- View/download PDF
6. Patient and public involvement in health research in Norway: a survey among researchers and patient organisations
- Author
-
Aas, Sigve Nyvik, Distefano, Marita Borg, Pettersen, Ingvild, Gravrok, Berit, Nordvoll, Laila Yvonne, Bjaastad, Jon Fauskanger, and Grimsgaard, Sameline
- Published
- 2023
- Full Text
- View/download PDF
7. Social inequality in prevalence of NCD risk factors: a cross-sectional analysis from the population-based Tromsø Study 2015–2016
- Author
-
Bjarne K Jacobsen, Jonas Johansson, Tom Wilsgaard, Laila Arnesdatter Hopstock, Sameline Grimsgaard, Inger Ariansen, and Rebecca A Hetland
- Subjects
Medicine - Abstract
Objective We aimed to examine associations between educational level, serving as an indicator of socioeconomic position, and prevalence of WHO-established leading behavioural and biological risk factors for non-communicable diseases (NCDs), in middle-aged to older women and men.Design Population-based cross-sectional study.Setting All inhabitants of the municipality of Tromsø, Norway, aged ≥40 years, were invited to the seventh survey (2015–2016) of the Tromsø Study; an ongoing population-based cohort study.Participants Of the 32 591 invited; 65% attended, and a total of 21 069 women (53%) and men aged 40–99 years were included in our study.Outcome measures We assessed associations between educational level and NCD behavioural and biological risk factors: daily smoking, physical inactivity (sedentary in leisure time), insufficient fruit/vegetable intake (10 g/day in women, >20 g/day in men), hypertension, obesity, intermediate hyperglycaemia and hypercholesterolaemia. These were expressed as odds ratios (OR) per unit decrease in educational level, with 95% CIs, in women and men.Results In women (results were not significantly different in men), we observed statistically significant associations between lower educational levels and higher odds of daily smoking (OR 1.69; 95% CI 1.60 to 1.78), physical inactivity (OR 1.38; 95% CI 1.31 to 1.46), insufficient fruit/vegetable intake (OR 1.54, 95% CI 1.43 to 1.66), hypertension (OR 1.25; 95% CI 1.20 to 1.30), obesity (OR 1.23; 95% CI 1.18 to 1.29), intermediate hyperglycaemia (OR 1.12; 95% CI 1.06 to 1.19), and hypercholesterolaemia (OR 1.07; 95% CI 1.03 to 1.12), and lower odds of harmful alcohol use (OR 0.75; 95% CI 0.72 to 0.78).Conclusion We found statistically significant educational gradients in women and men for all WHO-established leading NCD risk factors within a Nordic middle-aged to older general population. The prevalence of all risk factors increased at lower educational levels, except for harmful alcohol use, which increased at higher educational levels.
- Published
- 2024
- Full Text
- View/download PDF
8. Educational patterning in biological health seven years apart: Findings from the Tromsø Study
- Author
-
Neufcourt, Lola, Castagné, Raphaële, Wilsgaard, Tom, Grimsgaard, Sameline, Chadeau-Hyam, Marc, Vuckovic, Dragana, Ugarteche-Perez, Ainhoa, Farbu, Erlend Hoftun, Sandanger, Torkjel M., Delpierre, Cyrille, and Kelly-Irving, Michelle
- Published
- 2024
- Full Text
- View/download PDF
9. Patient and public involvement in health research in Norway: a survey among researchers and patient organisations
- Author
-
Sigve Nyvik Aas, Marita Borg Distefano, Ingvild Pettersen, Berit Gravrok, Laila Yvonne Nordvoll, Jon Fauskanger Bjaastad, and Sameline Grimsgaard
- Subjects
Patient and public involvement ,User representatives ,Health research ,Medicine ,Medicine (General) ,R5-920 - Abstract
Abstract Background Patient and public involvement (PPI) in health research may improve both the relevance and quality of the research. There is however a lack of research investigating the experiences, attitudes and barriers towards PPI in clinical research in Norway. The Norwegian Clinical Research Infrastructure Network therefore conducted a survey among researchers and PPI contributors aiming to investigate experiences with PPI and identify current challenges for successful involvement. Methods Two survey questionnaires were developed and distributed in October and November 2021. The survey targeting 1185 researchers was distributed from the research administrative system in the Regional Health Trusts. The survey targeting PPI contributors was distributed through Norwegian patient organisations, regional and national competence centers. Results The response rate was 30% among researchers and was unobtainable from PPI contributors due to the survey distribution strategy. PPI was most frequently used in the planning and conduct of the studies, and less utilized in dissemination and implementation of results. Both researchers and user representatives were generally positive to PPI, and agreed that PPI might be more useful in clinical research than in underpinning research. Researchers and PPI contributors who reported that roles and expectations were clarified in advance, were more likely to experience a common understanding of roles and responsibilities in the research project. Both groups pointed to the importance of earmarked funding for PPI activities. There was a demand for a closer collaboration between researchers and patient organisations to develop accessible tools and effective models for PPI in health research. Conclusions Surveys among clinical researchers and PPI contributors indicate overall positive attitudes towards PPI in clinical research. However, more resources, such as budget, time, and accessible tools, are needed. Clarifying roles and expectations, and creating new PPI models under resource constraints can enhance its effectiveness. PPI is underutilized in disseminating and implementing research results, presenting an opportunity for improving healthcare outcomes.
- Published
- 2023
- Full Text
- View/download PDF
10. Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation
- Author
-
Kaptoge, S, Seshasai, SRK, Sun, L, Walker, M, Bolton, T, Spackman, S, Ataklte, F, Willeit, P, Bell, S, Burgess, S, Pennells, L, Altay, S, Assmann, G, Ben-Shlomo, Y, Best, LG, Björkelund, C, Blazer, DG, Brenner, H, Brunner, EJ, Dagenais, GR, Cooper, JA, Cooper, C, Crespo, CJ, Cushman, M, D'Agostino, RB, Sr, Daimon, M, Daniels, LB, Danker, R, Davidson, KW, de Jongh, RT, Donfrancesco, C, Ducimetiere, P, Elders, PJM, Engström, G, Ford, I, Gallacher, I, Bakker, SJL, Goldbourt, U, de La Cámara, G, Grimsgaard, S, Gudnason, V, Hansson, PO, Imano, H, Jukema, JW, Kabrhel, C, Kauhanen, J, Kavousi, M, Kiechl, S, Knuiman, MW, Kromhout, D, Krumholz, HM, Kuller, LH, Laatikainen, T, Lowler, DA, Meyer, HE, Mukamal, K, Nietert, PJ, Ninomiya, T, Nitsch, D, Nordestgaard, BG, Palmieri, L, Price, JF, Ridker, PM, Sun, Q, Rosengren, A, Roussel, R, Sakurai, M, Salomaa, V, Schöttker, B, Shaw, JE, Strandberg, TE, Sundström, J, Tolonen, H, Tverdal, A, Verschuren, WMM, Völzke, H, Wagenknecht, L, Wallace, RB, Wannamethee, SG, Wareham, NJ, Wassertheil-Smoller, S, Yamagishi, K, Yeap, BB, Harrison, S, Inouye, M, Griffin, S, Butterworth, AS, Wood, AM, Thompson, SG, Sattar, N, Danesh, J, Di Angelantonio, E, Tipping, RW, Russell, S, Johansen, M, Bancks, MP, Mongraw-Chaffin, M, Magliano, D, Barr, ELM, Zimmet, PZ, Whincup, PH, Willeit, J, Leitner, C, Lawlor, DA, Elwood, P, Sutherland, SE, Hunt, KJ, Selmer, RM, Haheim, LL, Ariansen, I, Tybjaer-Hansen, A, Frikkle-Schmidt, R, Langsted, A, Lo Noce, C, Balkau, B, Bonnet, F, Fumeron, F, Pablos, DL, Ferro, CR, Morales, TG, Mclachlan, S, Guralnik, J, Khaw, KT, Holleczek, B, Stocker, H, Nissinen, A, Vartiainen, E, Jousilahti, P, Harald, K, Massaro, JM, Pencina, M, Lyass, A, Susa, S, Oizumi, T, Kayama, T, Chetrit, A, Roth, J, Orenstein, L, Welin, L, Svärdsudd, K, Lissner, L, Hange, D, Mehlig, K, Tilvis, RS, Dennison, E, Westbury, L, Norman, PE, Almeida, OP, Hankey, GJ, Hata, J, Shibata, M, Furuta, Y, Bom, MT, Rutters, F, Muilwijk, M, Kraft, P, Lindstrom, S, Turman, C, Kiyama, M, Kitamura, A, Gerber, Y, Salonen, JT, van Schoor, LN, van Zutphen, EM, Melander, O, Psaty, BM, Blaha, M, de Boer, IH, Kronmal, RA, Grandits, G, Shin, H-C, Albertorio, JR, Gillum, RF, Hu, FB, Humphries, S, Hill- Briggs, F, Vrany, E, Butler, M, Schwartz, JE, Iso, H, Amouyel, P, Arveiler, D, Ferrieres, J, Gansevoort, RT, de Boer, R, Kieneker, L, Trompet, S, Kearney, P, Cantin, B, Després, JP, Lamarche, B, Laughlin, G, McEvoy, L, Aspelund, T, Thorsson, B, Sigurdsson, G, Tilly, M, Ikram, MA, Dorr, M, Schipf, S, Fretts, AM, Umans, JG, Ali, T, Shara, N, Davey-Smith, G, Can, G, Yüksel, H, Özkan, U, Nakagawa, H, Morikawa, Y, Ishizaki, M, Njølstad, I, Wilsgaard, T, Mathiesen, E, Buring, J, Cook, N, Arndt, V, Rothenbacher, D, Manson, J, Tinker, L, Shipley, M, Tabak, AG, Kivimaki, M, Packard, C, Robertson, M, Feskens, E, and Geleijnse, M
- Published
- 2023
- Full Text
- View/download PDF
11. Lipid Levels During Adult Lifetime in Men and Women With and Without a Subsequent Incident Myocardial Infarction: A Longitudinal Analysis of Data From the Tromsø Study 1974 to 2016
- Author
-
Grethe Albrektsen, Tom Wilsgaard, Ivar Heuch, Maja‐Lisa Løchen, Dag Steinar Thelle, Inger Njølstad, Sameline Grimsgaard, and Kaare Harald Bønaa
- Subjects
incident myocardial infarction ,lipid profile ,longitudinal study ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background The atherosclerotic effect of an adverse lipid profile is assumed to accumulate throughout life, leading to increased risk of myocardial infarction (MI). Still, little is known about age at onset and duration of unfavorable lipid levels before MI. Methods and Results Longitudinal data on serum lipid levels for 26 130 individuals (50.5% women, aged 20–89 years) were obtained from 7 population‐based health surveys in Tromsø, Norway. Diagnoses of MI were obtained from national registers. A linear mixed model was applied to compare age‐ and sex‐specific mean values of total cholesterol, high‐density lipoprotein cholesterol (HDL‐C), and triglyceride concentration by MI status (MI versus non‐MI). Already from young adulthood, 20 to 35 years before the incident MI, individuals with a subsequent incident MI had on average more adverse lipid levels than individuals of the same age and sex without MI. Analogous to a dose–response relationship, there was a clear trend toward more severe adverse lipid levels the lower the age at incident MI (P
- Published
- 2023
- Full Text
- View/download PDF
12. Associations between postprandial triglyceride concentrations and sex, age, and body mass index: cross-sectional analyses from the Tromsø study 2015–2016
- Author
-
Mari Mikkelsen, Tom Wilsgaard, Sameline Grimsgaard, Laila A. Hopstock, and Patrik Hansson
- Subjects
lipids ,non-fasting triglycerides ,postprandial period ,time since last meal ,sex ,age ,Nutrition. Foods and food supply ,TX341-641 - Abstract
IntroductionElevated serum triglyceride concentrations increase the risk of developing atherosclerosis, the leading cause of cardiovascular disease. Postprandial triglyceride concentrations have shown to be a stronger predictor of cardiovascular disease compared to fasting triglycerides. It is therefore clinically relevant to study patterns of postprandial triglyceride concentrations in a general adult population.AimsThe aim of this cross-sectional analysis was to examine postprandial triglyceride concentrations in women and men, and the association with age, body mass index and menopausal status.MethodsNon-fasting blood samples from 20,963 women and men aged 40 years and older, attending the seventh survey of the Tromsø Study (2015–2016), were analyzed for postprandial triglyceride concentrations using descriptive statistics and linear regression models. Self-reported time since last meal before blood sampling was categorized into 1-h intervals with 7+ hours considered fasting.ResultsMen had higher triglyceride concentrations compared to women. The pattern of postprandial triglyceride concentrations differed between the sexes. In women, the highest triglyceride concentration (19% higher compared to fasting level, p < 0.001) was found 3–4 h postprandially compared to 1–3 h in men (30% higher compared to fasting level, p < 0.001). In women, all subgroups of age and BMI had higher triglyceride concentrations than the reference group (age 40–49 years and BMI < 25 kg/m2), but no linear trend for age was observed. In men, triglyceride concentrations were inversely associated with age. Body mass index was positively associated with triglyceride concentration in both women (p < 0.001) and men (p < 0.001), although this association was somewhat modified by age in women. Postmenopausal women had significantly higher triglyceride concentrations compared to premenopausal women (p < 0.05).ConclusionPostprandial triglyceride concentrations differed in groups of sex, age, body mass index, and menopausal status.
- Published
- 2023
- Full Text
- View/download PDF
13. Management
- Author
-
Grimsgaard, Wanda, primary
- Published
- 2022
- Full Text
- View/download PDF
14. Design
- Author
-
Grimsgaard, Wanda, primary
- Published
- 2022
- Full Text
- View/download PDF
15. Strategy
- Author
-
Grimsgaard, Wanda, primary
- Published
- 2022
- Full Text
- View/download PDF
16. Insight
- Author
-
Grimsgaard, Wanda, primary
- Published
- 2022
- Full Text
- View/download PDF
17. Production
- Author
-
Grimsgaard, Wanda, primary
- Published
- 2022
- Full Text
- View/download PDF
18. Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study
- Author
-
Tiwari, Sweta, Cerin, Ester, Wilsgaard, Tom, Løvsletten, Ola, Njølstad, Inger, Grimsgaard, Sameline, Hopstock, Laila A., Schirmer, Henrik, Rosengren, Annika, Kristoffersen, Kathrine, and Løchen, Maja-Lisa
- Published
- 2022
- Full Text
- View/download PDF
19. Dataset of fitness trackers and smartwatches to measuring physical activity in research
- Author
-
Henriksen, André, Woldaregay, Ashenafi Zebene, Muzny, Miroslav, Hartvigsen, Gunnar, Hopstock, Laila Arnesdatter, and Grimsgaard, Sameline
- Published
- 2022
- Full Text
- View/download PDF
20. Simple cardiovascular risk stratification by replacing total serum cholesterol with anthropometric measures: The MORGAM prospective cohort project
- Author
-
Rosberg, Victoria, Vishram-Nielsen, Julie KK, Kristensen, Anna M. Dyrvig, Pareek, Manan, Sehested, Thomas S.G., Nilsson, Peter M, Linneberg, Allan, Palmieri, Luigi, Giampaoli, Simona, Donfrancesco, Chiara, Kee, Frank, Mancia, Giuseppe, Cesana, Giancarlo, Veronesi, Giovanni, Grassi, Guido, Kuulasmaa, Kari, Salomaa, Veikko, Palosaari, Tarja, Sans, Susana, Ferrieres, Jean, Dallongeville, Jean, Söderberg, Stefan, Moitry, Marie, Drygas, Wojciech, Tamosiunas, Abdonas, Peters, Annette, Brenner, Hermann, Schöttker, Ben, Grimsgaard, Sameline, Biering-Sørensen, Tor, and Olsen, Michael H
- Published
- 2022
- Full Text
- View/download PDF
21. When Visualization and Virtual Reality Made a Paradigm Shift in Oil and Gas
- Author
-
Lidal, Endre M., Langeland, Tor, Grimsgaard, Jens, and Patel, Daniel, editor
- Published
- 2021
- Full Text
- View/download PDF
22. On the Care of Children Entrusted in our Hands: Reflections on the Position of Knowledge in Ethics-Based Practices
- Author
-
Nordtug, Birgit, Grimsgaard, Cathrine, Gruber, Craig W., Series Editor, Valsiner, Jaan, Series Editor, Clark, Matthew G., Series Editor, Klempe, Sven Hroar, Series Editor, and Knizek, Birthe Loa, editor
- Published
- 2021
- Full Text
- View/download PDF
23. Dataset of fitness trackers and smartwatches to measuring physical activity in research
- Author
-
André Henriksen, Ashenafi Zebene Woldaregay, Miroslav Muzny, Gunnar Hartvigsen, Laila Arnesdatter Hopstock, and Sameline Grimsgaard
- Subjects
Motor activity ,Activity tracker ,Smart watch ,Heart rate ,Photoplethysmography ,Wearables ,Medicine ,Biology (General) ,QH301-705.5 ,Science (General) ,Q1-390 - Abstract
Abstract Objectives Accelerometer-based wrist-worn fitness trackers and smartwatches (wearables) appeared on the consumer market in 2011. Many wearable devices have been released since. The objective of this data paper is to describe a dataset of 423 wearables released before July 2017. Data description We identified wearables and extracted information from six online and offline databases. We also visited websites for all identified companies/brands to identify additional wearables, as well as obtained additional information for each identified device. Twelve attributes were collected: wearable name, company/brand name, release year, country of origin, whether the wearable was crowd funded, form factor (fitness tracker or smartwatch), and sensors supported. Support for the following sensors were mapped: accelerometer, magnetometer, gyroscope, altimeter or barometer, global-positioning-system, and optical pulse sensor (i.e., photoplethysmograph). The search was conducted between May 15th and July 1st, 2017. The included data gives an overview of most in-scope wearables released before July 2017 and allows researchers to conduct additional analysis not performed in the related article. Further insights can be achieved by complementing this list with wearable models released after July 2017.
- Published
- 2022
- Full Text
- View/download PDF
24. Social inequality in prevalence of NCD risk factors: a cross-sectional analysis from the population-based Tromsø Study 2015–2016
- Author
-
Hetland, Rebecca A, primary, Wilsgaard, Tom, additional, Hopstock, Laila Arnesdatter, additional, Ariansen, Inger, additional, Johansson, Jonas, additional, Jacobsen, Bjarne K, additional, and Grimsgaard, Sameline, additional
- Published
- 2024
- Full Text
- View/download PDF
25. Anthropometric measures are satisfactory substitutes for the DXA‐derived visceral adipose tissue in the association with cardiometabolic risk—The Tromsø Study 2015–2016
- Author
-
Marie W. Lundblad, Bjarne K. Jacobsen, Jonas Johansson, Sameline Grimsgaard, Lene F. Andersen, and Laila A. Hopstock
- Subjects
cardiometabolic health ,dual energy x‐ray absorptiometry ,obesity ,overweight ,population studies ,visceral adipose tissue ,Internal medicine ,RC31-1245 - Abstract
Abstract Background Body mass index (BMI) increases while cardiometabolic risk factors decrease in individuals in high‐income countries. This paradoxical observation raises the question of whether current measures of overweight and obesity properly identify cardiometabolic risk. Methods A total of 3675 participants (59% women) aged 40–84 years with whole‐body dual‐energy x‐ray absorptiometry scans from the seventh survey of the Tromsø Study were included to examine the association between visceral adipose tissue (VAT) in grams and BMI, waist circumference (WC), waist‐to‐hip ratio (WHR), and waist‐to‐height ratio (WHtR). Further, their association with single cardiometabolic risk factors (blood pressure, triglycerides, total cholesterol, high‐density lipoprotein [HDL] cholesterol, glycated hemoglobin, high‐sensitivity C‐reactive protein), modified single components from the ATP Ⅲ criteria for metabolic syndrome (hypertension, diabetes, high triglycerides, and low HDL cholesterol), and metabolic syndrome were examined. Results VAT mass was strongly correlated with BMI (r ≥ 0.77), WC (r ≥ 0.80), WHR (r ≥ 0.58), and WHtR (r ≥ 0.78). WC was the strongest predictor for VAT (area under the curve: 0.90). Compared to anthropometric measures, the associations between VAT and metabolic syndrome as well as single components of metabolic syndrome were statistically significantly stronger, but the clinical differences were likely minor. Conclusion Although VAT mass showed statistically stronger associations with cardiometabolic risk compared to traditional anthropometrics, the clinical importance was likely small. Simple, clinically available tools seem to satisfactory substitute for VAT to identify cardiometabolic risk.
- Published
- 2021
- Full Text
- View/download PDF
26. Complex lifestyle intervention among inactive older adults with elevated cardiovascular disease risk and obesity: a mixed-method, single-arm feasibility study for RESTART—a randomized controlled trial
- Author
-
Trygve S. Deraas, Laila Hopstock, Andre Henriksen, Bente Morseth, Anne Sofie Sand, Inger Njølstad, Sigurd Pedersen, Edvard Sagelv, Jonas Johansson, and Sameline Grimsgaard
- Subjects
Feasibility study ,Older adults ,Lifestyle intervention ,Primary prevention ,Cardiovascular disease risk ,Obesity ,Medicine (General) ,R5-920 - Abstract
Abstract Background Physical inactivity and obesity are global public health challenges. Older adults are important to target for prevention and management of disease and chronic conditions. However, many individuals struggle with maintaining increased physical activity (PA) and improved diet. This feasibility study provides the foundation for the RESTART trial, a randomized controlled trial (RCT) to test a complex intervention to facilitate favourable lifestyle changes older adults can sustain. The primary objective of this study was to investigate study feasibility (recruitment, adherence, side-effects, and logistics) using an interdisciplinary approach. Methods This 1-year prospective mixed-method single-arm feasibility study was conducted in Tromsø, Norway, from September 2017. We invited by mail randomly selected participants from the seventh survey of the Tromsø Study (2015–2016) aged 55–75 years with sedentary lifestyle, obesity, and elevated cardiovascular risk. Participants attended a 6-month complex lifestyle intervention program, comprising instructor-led high-intensive exercise and nutritionist- and psychologist-led counselling, followed by a 6-month follow-up. All participants used a Polar activity tracker for daily activity monitoring during the intervention. Participants were interviewed three times throughout the study. Primary outcome was study feasibility measures. Results We invited potential participants (n=75) by mail of which 27 % (n=20) agreed to participate. Telephone screening excluded four participants, and altogether 16 participants completed baseline screening. The intervention and test procedures of primary and secondary outcomes were feasible and acceptable for the participants. There were no exercise-induced injuries, indicating that the intervention program is safe. Participants experienced that the dietary and psychological counselling were delivered too early in the intervention and in too close proximity to the start of the exercise program. Minor logistic improvements were implemented throughout the intervention period. Conclusion This study indicates that it is feasible to conduct a full-scale RCT of a multi-component randomized intervention trial, based on the model of the present study. No dropouts due to exercise-induced injury indicates that the exercises were safe. While minor improvements in logistics were implemented during the intervention, we will improve recruitment and adherence strategies, rearrange schedule of intervention contents (exercise, diet, and psychology), as well as improve the content of the dietary and behavioural counselling to maximize outcome effects in the RESTART protocol. Trial registration ClinicalTrials.gov Identifier: NCT03807323 Registered 16 January 2019 – retrospectively registered.
- Published
- 2021
- Full Text
- View/download PDF
27. Validating Acute Myocardial Infarction Diagnoses in National Health Registers for Use as Endpoint in Research: The Tromsø Study
- Author
-
Varmdal T, Mathiesen EB, Wilsgaard T, Njølstad I, Nyrnes A, Grimsgaard S, Bønaa KH, Mannsverk J, and Løchen ML
- Subjects
cardiovascular diseases ,data quality ,registers ,data collection ,quality control ,Infectious and parasitic diseases ,RC109-216 - Abstract
Torunn Varmdal,1,2 Ellisiv B Mathiesen,1,3 Tom Wilsgaard,1 Inger Njølstad,1 Audhild Nyrnes,1 Sameline Grimsgaard,1 Kaare Harald Bønaa,2,4 Jan Mannsverk,1 Maja-Lisa Løchen1,5 1Department of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway; 2Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway; 3Department of Neurology, University Hospital of North Norway, Tromsø, Norway; 4Clinic for Heart Disease, St. Olav’s University Hospital, Trondheim, Norway; 5Department of Cardiology, University Hospital of North Norway, Tromsø, NorwayCorrespondence: Torunn VarmdalDepartment of Community Medicine, UiT The Arctic University of Norway, Postboks 6050 Langnes, Tromsø, 9037, NorwayTel +47 930 28 286Email torunn.varmdal@ntnu.noPurpose: To assess whether acute myocardial infarction (MI) diagnoses in national health registers are sufficiently correct and complete to replace manual collection of endpoint data for a population-based, epidemiological study.Patients and Methods: Using the Tromsø Study Cardiovascular Disease Register for 2013– 2014 as gold standard, we calculated correctness (defined as positive predictive value (PPV)) and completeness (defined as sensitivity) of MI cases in the Norwegian Myocardial Infarction Register and the Norwegian Patient Register separately and in combination. We calculated the sensitivity and PPV with 95% confidence intervals using the Clopper-Pearson Exact test.Results: We identified 153 MI cases in the gold standard. In the Norwegian Myocardial Infarction Register, we found a PPV of 97.1% (95% confidence interval (CI) 92.8– 99.2) and a sensitivity of 88.2% (95% CI 82.0– 92.9). In the Norwegian Patient Register, the PPV was 96.3% (95% CI 91.6– 98.8) and the sensitivity was 85.6% (95% CI 79.0– 90.8). The combined dataset of the Norwegian Myocardial Infarction Register and the Norwegian Patient Register had a PPV of 96.6% (95% CI 92.1– 98.9) and a sensitivity of 91.5% (95% CI 85.9– 95.4).Conclusion: MI diagnoses in both the Norwegian Myocardial Infarction Register and the Norwegian Patient Register were highly correct and complete, and each of the registers could be considered as endpoint sources for the Tromsø Study. A combination of the two national registers seemed, however, to represent the most comprehensive data source overall. The benefits of using data from national registers as endpoints in epidemiological studies include faster, less resource-intensive access to nationwide data and considerably lower loss to follow-up, compared to manual data collection in a limited geographical area.Keywords: cardiovascular diseases, data quality, registers, data collection, quality control
- Published
- 2021
28. Moderate‐to‐vigorous physical activity modifies the relationship between sedentary time and sarcopenia: the Tromsø Study 2015–2016
- Author
-
Jonas Johansson, Bente Morseth, David Scott, Bjørn Heine Strand, Laila A. Hopstock, and Sameline Grimsgaard
- Subjects
Sarcopenia ,Physical activity ,Sedentary behaviour ,Accelerometers ,The Tromsø Study ,Diseases of the musculoskeletal system ,RC925-935 ,Human anatomy ,QM1-695 - Abstract
Abstract Background Sarcopenia is an age‐related muscle disease primarily characterized by reductions in muscle strength that increases the risk of falls, fractures, cognitive impairment, and mortality. Exercise is currently preferred in prevention and treatment, but it is unknown how different habitual physical activity and sedentary behaviour patterns associate with sarcopenia status. The purpose of the present study was to compare associations of these patterns with probable sarcopenia in older adults. Methods In 3653 community‐dwelling participants (51% women) aged 60–84 years from the seventh survey of the Tromsø Study, we assessed objective physical activity and sedentary behaviour collected over 8 days (ActiGraph wGT3X‐BT Accelerometer), grip strength (Jamar+ Digital Dynamometer), five‐repetition chair stands, and self‐reported disease. We combined tertiles of sedentary (SED) time and moderate‐to‐vigorous physical activity (MVPA) to create nine different activity profiles (SEDHIGH, SEDMOD, and SEDLOW combined with MVPAHIGH, MVPAMOD, or MVPALOW). Multiple logistic regression models were used to examine how these profiles associated with probable sarcopenia, defined by low handgrip strength and/or slow chair stands time according to the revised European Working Group on Sarcopenia in Older People criteria. Results Probable sarcopenia was present in 227 (6.2%) participants. Men with probable sarcopenia had on average 35.3 min more SED time and 20 min less MVPA compared with participants without sarcopenia (P
- Published
- 2021
- Full Text
- View/download PDF
29. Patient and public involvement in health research : A Nordic perspective
- Author
-
SAND, ANNE-SOFIE, GRIMSGAARD, SAMELINE, and PETTERSEN, INGVILD
- Published
- 2020
30. Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study
- Author
-
Sweta Tiwari, Ester Cerin, Tom Wilsgaard, Ola Løvsletten, Inger Njølstad, Sameline Grimsgaard, Laila A. Hopstock, Henrik Schirmer, Annika Rosengren, Kathrine Kristoffersen, and Maja-Lisa Løchen
- Subjects
Area level socio-economic status ,Cardiovascular disease ,Risk factors ,Mediation ,Public aspects of medicine ,RA1-1270 ,Social sciences (General) ,H1-99 - Abstract
Introduction: Cardiovascular disease (CVD) is a leading cause of death and disability and living in areas with low socio-economic status (SES) is associated with increased risk of CVD. Lifestyle factors such as smoking, physical inactivity, an unhealthy diet and harmful alcohol use are main risk factors that contribute to other modifiable risk factors, such as hypertension, raised blood cholesterol, obesity, and diabetes. The potential impact of area-level socio-economic status (ASES) on metabolic CVD risk factors via lifestyle behaviors independent of individual SES has not been investigated previously. Aims: To estimate associations of ASES with CVD risk factors and the mediating role of lifestyle behaviors independent of individual-level SES. Methods: In this cross-sectional study, we included 19,415 participants (52% women) from the seventh survey of the Tromsø Study (2015–2016) (Tromsø7). The exposure variable ASES was created by aggregating individual-level SES variables (education, income, housing ownership) at the geographical subdivision level. Individual-level SES data and geographical subdivision of Tromsø municipality (36 areas) were obtained from Statistics Norway. Variables from questionnaires and clinical examinations obtained from Tromsø7 were used as mediators (smoking, snuff, alcohol, and physical activity), while the outcome variables were body mass index (BMI), total/high-density lipoprotein (HDL) cholesterol ratio, waist circumference, hypertension, diabetes. Mediation and mediated moderation analysis were performed with age as a moderator, stratified by sex. Results: ASES was significantly associated with all outcome variables. CVD risk factor level declined with an increase in ASES. These associations were mediated by differences in smoking habits, alcohol use and physical activity. The associations of ASES with total/HDL cholesterol ratio and waist circumference (women) were moderated by age, and the moderating effects were mediated by smoking and physical activity in both sexes. The largest mediated effects were seen in the associations of ASES with total/HDL cholesterol ratio, with the mediators accounting for 43% of the observed effects. Conclusions: Living in lower SES areas is associated with increased CVD risk due to unhealthy lifestyle behaviors, such as smoking, alcohol use and physical inactivity. These associations were stronger in women and among older participants.
- Published
- 2022
- Full Text
- View/download PDF
31. Barns deltakelse som en vilje til ikke å la seg styre
- Author
-
Grimsgaard, Cathrine, primary
- Published
- 2022
- Full Text
- View/download PDF
32. Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors: an analysis of 49 cohorts from 11 European countries
- Author
-
Reinikainen, J, Kuulasmaa, K, Oskarsson, V, Amouyel, P, Biasch, K, Brenner, H, De Ponti, R, Donfrancesco, C, Drygas, W, Ferrieres, J, Grassi, G, Grimsgaard, S, Iacoviello, L, Jousilahti, P, Kårhus, L, Kee, F, Linneberg, A, Luksiene, D, Mariño, J, Moitry, M, Palmieri, L, Peters, A, Piwonska, A, Quarti-Trevano, F, Salomaa, V, Sans, S, Schmidt, C, Schöttker, B, Söderberg, S, Tamosiunas, A, Thorand, B, Tunstall-Pedoe, H, Vanuzzo, D, Veronesi, G, Woodward, M, Lekadir, K, Niiranen, T, Kårhus, LL, Schmidt, CO, Reinikainen, J, Kuulasmaa, K, Oskarsson, V, Amouyel, P, Biasch, K, Brenner, H, De Ponti, R, Donfrancesco, C, Drygas, W, Ferrieres, J, Grassi, G, Grimsgaard, S, Iacoviello, L, Jousilahti, P, Kårhus, L, Kee, F, Linneberg, A, Luksiene, D, Mariño, J, Moitry, M, Palmieri, L, Peters, A, Piwonska, A, Quarti-Trevano, F, Salomaa, V, Sans, S, Schmidt, C, Schöttker, B, Söderberg, S, Tamosiunas, A, Thorand, B, Tunstall-Pedoe, H, Vanuzzo, D, Veronesi, G, Woodward, M, Lekadir, K, Niiranen, T, Kårhus, LL, and Schmidt, CO
- Abstract
Aims: The regional and temporal differences in the associations between cardiovascular disease (CVD) and its classic risk factors are unknown. The current study examined these associations in different European regions over a 30-year period. Methods and results: The study sample comprised 553 818 individuals from 49 cohorts in 11 European countries (baseline: 1982-2012) who were followed up for a maximum of 10 years. Risk factors [sex, smoking, diabetes, non-HDL cholesterol, systolic blood pressure (BP), and body mass index (BMI)] and CVD events (coronary heart disease or stroke) were harmonized across cohorts. Risk factor-outcome associations were analysed using multivariable-adjusted Cox regression models, and differences in associations were assessed using meta-regression. The differences in the risk factor-CVD associations between central Europe, northern Europe, southern Europe, and the UK were generally small. Men had a slightly higher hazard ratio (HR) in southern Europe (P = 0.043 for overall difference), and those with diabetes had a slightly lower HR in central Europe (P = 0.022 for overall difference) compared with the other regions. Of the six CVD risk factors, minor HR decreases per decade were observed for non-HDL cholesterol [7% per mmol/L; 95% confidence interval (CI), 3-10%] and systolic BP (4% per 20 mmHg; 95% CI, 1-8%), while a minor HR increase per decade was observed for BMI (7% per 10 kg/m2; 95% CI, 1-13%). Conclusion: The results demonstrate that all classic CVD risk factors are still relevant in Europe, irrespective of regional area. Preventive strategies should focus on risk factors with the greatest population attributable risk.
- Published
- 2024
33. Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors:an analysis of 49 cohorts from 11 European countries
- Author
-
Reinikainen, Jaakko, Kuulasmaa, Kari, Oskarsson, Viktor, Amouyel, Philippe, Biasch, Katia, Brenner, Hermann, De Ponti, Roberto, Donfrancesco, Chiara, Drygas, Wojciech, Ferrieres, Jean, Grassi, Guido, Grimsgaard, Sameline, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line L, Kee, Frank, Linneberg, Allan, Luksiene, Dalia, Mariño, Joany, Moitry, Marie, Palmieri, Luigi, Peters, Annette, Piwonska, Aleksandra, Quarti-Trevano, Fosca, Salomaa, Veikko, Sans, Susana, Schmidt, Carsten Oliver, Schöttker, Ben, Söderberg, Stefan, Tamosiunas, Abdonas, Thorand, Barbara, Tunstall-Pedoe, Hugh, Vanuzzo, Diego, Veronesi, Giovanni, Woodward, Mark, Lekadir, Karim, Niiranen, Teemu, Reinikainen, Jaakko, Kuulasmaa, Kari, Oskarsson, Viktor, Amouyel, Philippe, Biasch, Katia, Brenner, Hermann, De Ponti, Roberto, Donfrancesco, Chiara, Drygas, Wojciech, Ferrieres, Jean, Grassi, Guido, Grimsgaard, Sameline, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line L, Kee, Frank, Linneberg, Allan, Luksiene, Dalia, Mariño, Joany, Moitry, Marie, Palmieri, Luigi, Peters, Annette, Piwonska, Aleksandra, Quarti-Trevano, Fosca, Salomaa, Veikko, Sans, Susana, Schmidt, Carsten Oliver, Schöttker, Ben, Söderberg, Stefan, Tamosiunas, Abdonas, Thorand, Barbara, Tunstall-Pedoe, Hugh, Vanuzzo, Diego, Veronesi, Giovanni, Woodward, Mark, Lekadir, Karim, and Niiranen, Teemu
- Abstract
Aims The regional and temporal differences in the associations between cardiovascular disease (CVD) and its classic risk factors are unknown. The current study examined these associations in different European regions over a 30-year period. Methods and results The study sample comprised 553 818 individuals from 49 cohorts in 11 European countries (baseline: 1982–2012) who were followed up for a maximum of 10 years. Risk factors [sex, smoking, diabetes, non-HDL cholesterol, systolic blood pressure (BP), and body mass index (BMI)] and CVD events (coronary heart disease or stroke) were harmonized across cohorts. Risk factor–outcome associations were analysed using multivariable-adjusted Cox regression models, and differences in associations were assessed using meta-regression. The differences in the risk factor–CVD associations between central Europe, northern Europe, southern Europe, and the UK were generally small. Men had a slightly higher hazard ratio (HR) in southern Europe (P = 0.043 for overall difference), and those with diabetes had a slightly lower HR in central Europe (P = 0.022 for overall difference) compared with the other regions. Of the six CVD risk factors, minor HR decreases per decade were observed for non-HDL cholesterol [7% per mmol/L; 95% confidence interval (CI), 3–10%] and systolic BP (4% per 20 mmHg; 95% CI, 1–8%), while a minor HR increase per decade was observed for BMI (7% per 10 kg/m2; 95% CI, 1–13%). Conclusion The results demonstrate that all classic CVD risk factors are still relevant in Europe, irrespective of regional area. Preventive strategies should focus on risk factors with the greatest population attributable risk., AIMS: The regional and temporal differences in the associations between cardiovascular disease (CVD) and its classic risk factors are unknown. The current study examined these associations in different European regions over a 30-year period.METHODS AND RESULTS: The study sample comprised 553 818 individuals from 49 cohorts in 11 European countries (baseline: 1982-2012) who were followed up for a maximum of 10 years. Risk factors [sex, smoking, diabetes, non-HDL cholesterol, systolic blood pressure (BP), and body mass index (BMI)] and CVD events (coronary heart disease or stroke) were harmonized across cohorts. Risk factor-outcome associations were analysed using multivariable-adjusted Cox regression models, and differences in associations were assessed using meta-regression. The differences in the risk factor-CVD associations between central Europe, northern Europe, southern Europe, and the UK were generally small. Men had a slightly higher hazard ratio (HR) in southern Europe (P = 0.043 for overall difference), and those with diabetes had a slightly lower HR in central Europe (P = 0.022 for overall difference) compared with the other regions. Of the six CVD risk factors, minor HR decreases per decade were observed for non-HDL cholesterol [7% per mmol/L; 95% confidence interval (CI), 3-10%] and systolic BP (4% per 20 mmHg; 95% CI, 1-8%), while a minor HR increase per decade was observed for BMI (7% per 10 kg/m2; 95% CI, 1-13%).CONCLUSION: The results demonstrate that all classic CVD risk factors are still relevant in Europe, irrespective of regional area. Preventive strategies should focus on risk factors with the greatest population attributable risk.
- Published
- 2024
34. Polar Vantage and Oura Physical Activity and Sleep Trackers: Validation and Comparison Study
- Author
-
André Henriksen, Frode Svartdal, Sameline Grimsgaard, Gunnar Hartvigsen, and Laila Arnesdatter Hopstock
- Subjects
Medicine - Abstract
BackgroundConsumer-based activity trackers are increasingly used in research, as they have the potential to promote increased physical activity and can be used for estimating physical activity among participants. However, the accuracy of newer consumer-based devices is mostly unknown, and validation studies are needed. ObjectiveThe objective of this study was to compare the Polar Vantage watch (Polar Electro Oy) and Oura ring (generation 2; Ōura Health Oy) activity trackers to research-based instruments for measuring physical activity, total energy expenditure, resting heart rate, and sleep duration in free-living adults. MethodsA total of 21 participants wore 2 consumer-based activity trackers (Polar watch and Oura ring), an ActiGraph accelerometer (ActiGraph LLC), and an Actiheart accelerometer and heart rate monitor (CamNtech Ltd) and completed a sleep diary for up to 7 days. We assessed Polar watch and Oura ring validity and comparability for measuring physical activity, total energy expenditure, resting heart rate (Oura), and sleep duration. We analyzed repeated measures correlations, Bland-Altman plots, and mean absolute percentage errors. ResultsThe Polar watch and Oura ring values strongly correlated (P
- Published
- 2022
- Full Text
- View/download PDF
35. An evaluation of the facilitator training to implement ‘Taking charge of my life and health’, a peer-led group program to promote self-care and patient empowerment in Veteran participants
- Author
-
Abadi, Melissa H., Drake, Connor, Richard, Bonnie O., Schweinhart, April, Rychener, David, Shamblen, Stephen R., and Grimsgaard, Sara N.
- Published
- 2020
- Full Text
- View/download PDF
36. A breathing space: how young Norwegian women engaging psychomotor physiotherapy to address long-term health disorders narrate their experiences.
- Author
-
Grimsgaard, Elisabeth, Eik, Hedda, Bjorbækmoe, Wenche, and Ahlsen, Birgitte
- Abstract
IntroductionObjectiveMethodFindingsConclusionIn Norway, as elsewhere, young people may experience psychological distress and long-lasting pain. Such health disorders can be complex, leading some young people to seek psychomotor physiotherapy treatment. Thus far, however, there has been little qualitative investigation of their experiences.The purpose of this study was to gain new knowledge about the illness experiences of young people with long-term health disorders engaging psychomotor physiotherapy.Qualitative interviews with ten Norwegian women aged 16–24 in psychomotor physiotherapy were analyzed within a narrative framework.The participants’ treatment experiences take place in the context of a long history of pain, distress, and lack of understanding and support. Their stories tell of being threatened by illness and other difficult life events, and of being placed under further stress by a prolonged and disruptive quest for help within the healthcare system. For participants, psychomotor physiotherapy represents a breathing space where their illness experiences are acknowledged, enabling them to find rest and explore their bodily reactions and habits.Long-term health disorders represent significant disruptions to the daily lives and relationships of young women. It is important to acknowledge the illness experiences of these young women and establish trustful therapeutic relationships. Psychomotor physiotherapy may offer significant potential as a means to help young people explore and make sense of their illness experiences. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
37. Differences in sarcopenia prevalence between upper-body and lower-body based EWGSOP2 muscle strength criteria: the Tromsø study 2015–2016
- Author
-
Jonas Johansson, Bjørn Heine Strand, Bente Morseth, Laila Arnesdatter Hopstock, and Sameline Grimsgaard
- Subjects
Sarcopenia ,Prevalence ,EWGSOP2 ,Cohort ,The Tromsø study ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background The European Working Group on Sarcopenia in Older People (EWGSOP2) recommends grip strength and chair stand tests to be used as primary defining measures. It is unclear how either test affects prevalence estimates. Methods This cross-sectional study involved 3498 community-dwelling participants (40–84 years) from the 7th Tromsø Study survey (2015–2016). We used grip strength, five-repetition chair stands, four-meter Walk Speed Test, Timed-Up-and-Go (TUG) and Dual-Energy X-ray Absorptiometry measurements. Data were analyzed using multiple linear regression models and ROC-curves. Results Probable and confirmed sarcopenia prevalence was 1.3 and 4.4% based on grip strength and chair stands, respectively. There was very low agreement between grip strength and chair stand cut-offs (κ = 0.07), with only 4.3% of participants defined as having probable sarcopenia overlapping in the two criteria. Participants with grip strength-based sarcopenia had lower mean height, weight, waist circumference, and appendicular lean mass relative to body height (ALMheight 2) than non-sarcopenic participants (all p
- Published
- 2020
- Full Text
- View/download PDF
38. Simple cardiovascular risk stratification by replacing total serum cholesterol with anthropometric measures: The MORGAM prospective cohort project
- Author
-
Victoria Rosberg, Julie KK Vishram-Nielsen, Anna M. Dyrvig Kristensen, Manan Pareek, Thomas S.G. Sehested, Peter M Nilsson, Allan Linneberg, Luigi Palmieri, Simona Giampaoli, Chiara Donfrancesco, Frank Kee, Giuseppe Mancia, Giancarlo Cesana, Giovanni Veronesi, Guido Grassi, Kari Kuulasmaa, Veikko Salomaa, Tarja Palosaari, Susana Sans, Jean Ferrieres, Jean Dallongeville, Stefan Söderberg, Marie Moitry, Wojciech Drygas, Abdonas Tamosiunas, Annette Peters, Hermann Brenner, Ben Schöttker, Sameline Grimsgaard, Tor Biering-Sørensen, and Michael H Olsen
- Subjects
Adipose tissue ,Assessment, risk ,Body mass index ,Cardiovascular diseases ,Cholesterol ,Waist-hip ratio ,Medicine - Abstract
To assess whether anthropometric measures (body mass index [BMI], waist-hip ratio [WHR], and estimated fat mass [EFM]) are independently associated with major adverse cardiovascular events (MACE), and to assess their added prognostic value compared with serum total-cholesterol. The study population comprised 109,509 individuals (53% men) from the MORGAM-Project, aged 19–97 years, without established cardiovascular disease, and not on antihypertensive treatment. While BMI was reported in all, WHR and EFM were reported in ∼52,000 participants. Prognostic importance of anthropometric measurements and total-cholesterol was evaluated using adjusted Cox proportional-hazards regression, logistic regression, area under the receiver-operating-characteristic curve (AUCROC), and net reclassification improvement (NRI). The primary endpoint was MACE, a composite of stroke, myocardial infarction, or death from coronary heart disease. Age interacted significantly with anthropometric measures and total-cholesterol on MACE (P ≤ 0.003), and therefore age-stratified analyses (
- Published
- 2022
- Full Text
- View/download PDF
39. Dataset of consumer-based activity trackers as a tool for physical activity monitoring in epidemiological studies during the COVID-19 Pandemic
- Author
-
André Henriksen, Erlend Johannessen, Gunnar Hartvigsen, Sameline Grimsgaard, and Laila Arnesdatter Hopstock
- Subjects
Energy expenditure ,Steps ,Smart watch ,Fitness tracker ,Public health ,Lockdown ,Computer applications to medicine. Medical informatics ,R858-859.7 ,Science (General) ,Q1-390 - Abstract
Physical activity (PA) data were downloaded from 113 participants who owned a Garmin or Fitbit activity tracker in 2019 and 2020. Upon participant authorization, data were automatically downloaded from the Garmin and Fitbit cloud storages. The mSpider tool, a solution for automatic and continuous data extraction from activity tracker providers, were used to download participant data. Available data are daily averages by year, as well as monthly averages between 2019 and 2020, for steps, activity energy expenditure (AEE), total energy expenditure (TEE), moderate-to-vigorous physical activity (MVPA), light PA (LPA), moderate PA (MPA), vigorous PA (VPA), and sedentary time. In addition, March 2020 was divided in two, giving the daily average before and after the Norwegian COVID-19 lockdown date. Raw daily values for these variables are also included in a separate file. In addition, daily values for non-wear time are also include as raw data.In a previous study, differences between months, i.e., comparing 2019 with 2020 for months between March to December, were analysed for steps, MVPA, and AEE [1]. Further insights may be achieved by exploring other variables. This includes: (1) monthly averages for TEE, LPA, MPA, VPA, and sedentary time, (2) yearly averages (2019 and 2020) for steps, MVPA, TEE, AEE, LPA, MPA, VPA, and sedentary time (3) monthly average for steps, MVPA, TEE, AEE, LPA, MPA, VPA, and sedentary time for January, February, and March 2019, as well as March 2020. Additional analysis can also be conducted on the raw data.
- Published
- 2022
- Full Text
- View/download PDF
40. Brukermedvirkning i forskning – for lite, for sent
- Author
-
Bjåstad, Jon Fauskanger, primary, Aas, Sigve Nyvik, primary, Distefano, Marita Borg, primary, Berglen, Gunnhild, primary, Haugen, Nikolai Raaby, primary, Gjesten, Martha Therese, primary, Erga, Aleksander Hagen, primary, Pettersen, Ingvild, primary, Nordvoll, Laila Yvonne, primary, Sundström, Mariann, primary, and Grimsgaard, Sameline, primary
- Published
- 2024
- Full Text
- View/download PDF
41. National health registries – a ‘goldmine’ for studying non-communicable disease occurrence in Norway – the NCDNOR project
- Author
-
NYSTAD, WENCHE, primary, HJELLVIK, VIDAR, additional, LARSEN, INGER K., additional, ROBSAHM, TRUDE E., additional, SUND, ERIK R., additional, KROKSTAD, STEINAR, additional, HOPSTOCK, LAILA A., additional, GRIMSGAARD, SAMELINE, additional, LANGHAMMER, ARNULF, additional, BRAMNESS, JØRGEN G., additional, WISLØFF, TORBJØRN, additional, LERGENMULLER, SIMON, additional, DALENE, KNUT E., additional, MEYER, HAAKON E., additional, HOLVIK, KRISTIN, additional, HELGELAND, JON, additional, KARLSTAD, ØYSTEIN, additional, and ARIANSEN, INGER, additional
- Published
- 2023
- Full Text
- View/download PDF
42. Lifestyle factors as mediators of area-level socioeconomic differentials in mental health and cognitive function: the Tromsø Study
- Author
-
Tiwari, Sweta, primary, Cerin, Ester, additional, Wilsgaard, Tom, additional, Løvsletten, Ola, additional, Grimsgaard, Sameline, additional, Hopstock, Laila Arnesdatter, additional, Schirmer, Henrik, additional, Rosengren, Annika, additional, Kristoffersen, Kathrine, additional, and Løchen, Maja-Lisa, additional
- Published
- 2023
- Full Text
- View/download PDF
43. Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors: an analysis of 49 cohorts from 11 European countries
- Author
-
Reinikainen, Jaakko, primary, Kuulasmaa, Kari, additional, Oskarsson, Viktor, additional, Amouyel, Philippe, additional, Biasch, Katia, additional, Brenner, Hermann, additional, De Ponti, Roberto, additional, Donfrancesco, Chiara, additional, Drygas, Wojciech, additional, Ferrieres, Jean, additional, Grassi, Guido, additional, Grimsgaard, Sameline, additional, Iacoviello, Licia, additional, Jousilahti, Pekka, additional, Kårhus, Line L, additional, Kee, Frank, additional, Linneberg, Allan, additional, Luksiene, Dalia, additional, Mariño, Joany, additional, Moitry, Marie, additional, Palmieri, Luigi, additional, Peters, Annette, additional, Piwonska, Aleksandra, additional, Quarti-Trevano, Fosca, additional, Salomaa, Veikko, additional, Sans, Susana, additional, Schmidt, Carsten Oliver, additional, Schöttker, Ben, additional, Söderberg, Stefan, additional, Tamosiunas, Abdonas, additional, Thorand, Barbara, additional, Tunstall-Pedoe, Hugh, additional, Vanuzzo, Diego, additional, Veronesi, Giovanni, additional, Woodward, Mark, additional, Lekadir, Karim, additional, and Niiranen, Teemu, additional
- Published
- 2023
- Full Text
- View/download PDF
44. Succeeding with prolonged usage of consumer-based activity trackers in clinical studies: a mixed methods approach
- Author
-
André Henriksen, Anne-Sofie Sand, Trygve Deraas, Sameline Grimsgaard, Gunnar Hartvigsen, and Laila Hopstock
- Subjects
Actigraphy ,Human activity ,Activity trackers ,Motor activity ,Intervention study ,Clinical trial ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Lack of physical activity (PA) is a risk factor for death and non-communicable disease. Despite this, more than one fourth of adults worldwide do not follow PA guidelines. As part of a feasibility study to test a complex intervention for increasing PA, we included a consumer-based activity tracker (AT) as a tool to measure PA outcomes and to track heart rate during exercise sessions. The aim of the present study was to identify factors that increase wear time when using a consumer-based AT for monitoring of participants in clinical research. Methods Sixteen participants aged 55–74 years, with obesity, sedentary lifestyle, and elevated cardiovascular risk were recruited to a 12-month feasibility study. Participants wore a Polar M430 AT to collect continuous PA data during a six-month intervention followed by 6 months of follow-up. We performed quantitative wear time analysis, tested the validity of the AT, and completed two rounds of qualitative interviews to investigate how individual wear-time was linked to participant responses. Results From 1 year of tracking, mean number of valid wear days were 292 (SD = 86), i.e. 80%. The Polar M430 provides acceptable measurements for total energy expenditure. Motivations for increased wear time were that participants were asked to wear it and the ability to track PA progress. Perceived usefulness included time keeping, heart rate- and sleep tracking, becoming more conscious about day-to-day activity, and improved understanding of which activity types were more effective for energy expenditure. Sources of AT annoyance were measurement inaccuracies and limited instruction for use. Suggestions for improvement were that the AT was big, unattractive, and complicated to use. Conclusions Adherence to wearing a consumer-based AT was high. Results indicate that it is feasible to use a consumer-based AT to measure PA over a longer period. Potential success factors for increased wear time includes adequate instruction for AT use, allowing participants to choose different AT designs, and using trackers with accurate measurements. To identify accurate trackers, AT validation studies in the target cohort may be needed. Trial registration U.S. National Library of Medicine, Clinical Trial registry: NCT03807323 ; Registered 16 September 2019 – Retrospectively registered.
- Published
- 2020
- Full Text
- View/download PDF
45. Complex lifestyle intervention among inactive older adults with elevated cardiovascular disease risk and obesity: a mixed-method, single-arm feasibility study for RESTART—a randomized controlled trial
- Author
-
Deraas, Trygve S., Hopstock, Laila, Henriksen, Andre, Morseth, Bente, Sand, Anne Sofie, Njølstad, Inger, Pedersen, Sigurd, Sagelv, Edvard, Johansson, Jonas, and Grimsgaard, Sameline
- Published
- 2021
- Full Text
- View/download PDF
46. Longitudinal changes in body composition and waist circumference by self-reported levels of physical activity in leisure among adolescents: the Tromsø study, Fit Futures
- Author
-
Nils Abel Aars, Bjarne K. Jacobsen, Bente Morseth, Nina Emaus, and Sameline Grimsgaard
- Subjects
Adolescence ,Body composition ,Longitudinal study ,Physical activity ,Sports medicine ,RC1200-1245 - Abstract
Abstract Background It is not clear how physical activity affects body composition in adolescents. Physical activity levels are often reduced during this period, and the relative proportion of body fat mass and lean mass undergo natural changes in growing adolescents. We aimed to examine whether self-reported physical activity in leisure time at baseline or change in activity during follow-up affect changes in four measures of body composition; body mass index (kg/m2), waist circumference, fat mass index (fat mass in kg/m2) and lean mass index (lean mass in kg/m2). Methods We used data from the Tromsø Study Fit Futures, which invited all first year students in upper secondary high school in two municipalities in northern Norway in 2010–2011. They were reexamined in 2012–2013. Longitudinal data was available for 292 boys and 354 girls. We used multiple linear regression analyses to assess whether self-reported level of physical activity in leisure time at baseline predicted changes in body composition, and analysis of covariance to assess the effects of change in level of activity during follow-up on change in body composition. All analyses were performed sex-specific, and a p-value of
- Published
- 2019
- Full Text
- View/download PDF
47. Energy and nutrient intakes in relation to National Nutrition Recommendations in a Norwegian population-based sample: the Tromsø Study 2015–16
- Author
-
Marie W. Lundblad, Lene Frost Andersen, Bjarne K. Jacobsen, Monica Hauger Carlsen, Anette Hjartåker, Sameline Grimsgaard, and Laila A. Hopstock
- Subjects
food frequency questionnaire ,public health ,population-based studies ,adult ,nutrient intake ,energy intake ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Introduction: According to the Global Burden of Disease project, unhealthy diet accounts for most of the disease burden in Norway. Current recommendations on nutrient intake in Norway reflect those published in the evidence-based Nordic Nutrition Recommendations from 2012 (NNR2012). Aim: To study energy and nutrient intakes and compliance with the NNR2012 among women and men in a population-based study. Methods: A total of 15,146 participants (aged 40–99 years) completed a validated food frequency questionnaire (261 questions on food items, meals, and beverages) in the seventh survey of the Tromsø Study in 2015–16; 11,425 participants were eligible for the current analysis. Nutrient intake was estimated by a food and nutrient calculation system at the University of Oslo, Norway. We compared energy, macronutrient, and micronutrient intakes with the NNR2012. Results: In total, 85% of the women and men were not in compliance with the maximum recommended intake of saturated fat, and 40 and 77% of women and men, respectively, were not in compliance with the lowest recommended intake of fiber. More than 30% of women and 25% of men had a relatively high probability of inadequate intake of vitamin D, and more than 10% of the men had a relatively high probability of inadequate intake of vitamin B6 and vitamin C. More than 20% of women and men had a high probability of excessive intake of niacin, and almost 40% of women had a high probability of excessive intake of vitamin A. Conclusion: Although most participants were in compliance with NNR2012, a large proportion of participants had higher intakes than maximum recommended for saturated fat, and lower than recommended for fiber and vitamin D.
- Published
- 2019
- Full Text
- View/download PDF
48. Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level: findings from the MORGAM project
- Author
-
Di Castelnuovo, A, Bonaccio, M, Costanzo, S, Mcelduff, P, Linneberg, A, Salomaa, V, Männistö, S, Ferrières, J, Dallongeville, J, Thorand, B, Brenner, H, Ferrario, M, Veronesi, G, Tamosiunas, A, Grimsgaard, S, Drygas, W, Malyutina, S, Söderberg, S, Nordendahl, M, Kee, F, Grassi, G, Dabboura, S, Borchini, R, Westermann, D, Schrage, B, Zeller, T, Kuulasmaa, K, Blankenberg, S, Donati, M, Iacoviello, L, de Gaetano, G, Di Castelnuovo, Augusto, Bonaccio, Marialaura, Costanzo, Simona, McElduff, Patrick, Linneberg, Allen, Salomaa, Veikko, Männistö, Satu, Ferrières, Jean, Dallongeville, Jean, Thorand, Barbara, Brenner, Hermann, Ferrario, Marco, Veronesi, Giovanni, Tamosiunas, Abdonas, Grimsgaard, Sameline, Drygas, Wojciech, Malyutina, Sofia, Söderberg, Stefan, Nordendahl, Maria, Kee, Frank, Grassi, Guido, Dabboura, Salim, Borchini, Rossana, Westermann, Dirk, Schrage, Benedikt, Zeller, Tanja, Kuulasmaa, Kari, Blankenberg, Stefan, Donati, Maria Benedetta, Iacoviello, Licia, de Gaetano, Giovanni, Di Castelnuovo, A, Bonaccio, M, Costanzo, S, Mcelduff, P, Linneberg, A, Salomaa, V, Männistö, S, Ferrières, J, Dallongeville, J, Thorand, B, Brenner, H, Ferrario, M, Veronesi, G, Tamosiunas, A, Grimsgaard, S, Drygas, W, Malyutina, S, Söderberg, S, Nordendahl, M, Kee, F, Grassi, G, Dabboura, S, Borchini, R, Westermann, D, Schrage, B, Zeller, T, Kuulasmaa, K, Blankenberg, S, Donati, M, Iacoviello, L, de Gaetano, G, Di Castelnuovo, Augusto, Bonaccio, Marialaura, Costanzo, Simona, McElduff, Patrick, Linneberg, Allen, Salomaa, Veikko, Männistö, Satu, Ferrières, Jean, Dallongeville, Jean, Thorand, Barbara, Brenner, Hermann, Ferrario, Marco, Veronesi, Giovanni, Tamosiunas, Abdonas, Grimsgaard, Sameline, Drygas, Wojciech, Malyutina, Sofia, Söderberg, Stefan, Nordendahl, Maria, Kee, Frank, Grassi, Guido, Dabboura, Salim, Borchini, Rossana, Westermann, Dirk, Schrage, Benedikt, Zeller, Tanja, Kuulasmaa, Kari, Blankenberg, Stefan, Donati, Maria Benedetta, Iacoviello, Licia, and de Gaetano, Giovanni
- Abstract
The association between socioeconomic status (SES) and alcohol-related diseases has been widely explored. Less is known, however, on whether the association of moderate drinking with all-cause mortality is modified by educational level (EL). Using harmonized data from 16 cohorts in the MORGAM Project (N = 142,066) the association of pattern of alcohol intake with hazard of all-cause mortality across EL (lower = primary-school; middle = secondary-school; higher = university/college degree) was assessed using multivariable Cox-regression and spline curves. A total of 16,695 deaths occurred in 11.8 years (median). In comparison with life-long abstainers, participants drinking 0.1–10 g/d of ethanol had 13% (HR = 0.87; 95%CI: 0.74–1.02), 11% (HR = 0.89; 0.84–0.95) and 5% (HR = 0.95; 0.89–1.02) lower rate of death in higher, middle and lower EL, respectively. Conversely, drinkers > 20 g/d had 1% (HR = 1.01; 0.82–1.25), 10% (HR = 1.10; 1.02–1.19) and 17% (HR = 1.17; 1.09–1.26) higher rate of death. The association of alcohol consumption with all-cause mortality was nonlinear, with a different J-shape by EL levels. It was consistent across both sexes and in various approaches of measuring alcohol consumption, including combining quantity and frequency and it was more evident when the beverage of preference was wine. We observed that drinking in moderation (≤ 10 g/d) is associated with lower mortality rate more evidently in individuals with higher EL than in people with lower EL, while heavy drinking is associated with higher mortality rate more evidently in individuals with lower EL than in people with higher EL, suggesting that advice on reducing alcohol intake should especially target individuals of low EL.
- Published
- 2023
49. Samtaler mellom profesjonelle og barn som har psykisk syke eller rusavhengige foreldre : Et etisk og narrativt perspektiv
- Author
-
Grimsgaard, Cathrine
- Abstract
Dette er en vitenskapelig monografi basert på avhandlingen Om å holde noe av et barns liv i sin hånd. Samtaler mellom profesjonelle og barn som har psykisk syke eller rusavhengige foreldre: et etisk og narrativt perspektiv. Tema er barns deltakelse i samtalegrupper for barn som har psykisk syke eller rusavhengige foreldre. Boken bygger på erfaringer fra deltakende observasjon i sju forskjellige samtalegrupper samt oppfølgende samtaler med barna som deltok og de profesjonelle som ledet gruppene. Formålet har vært å undersøke hvilke muligheter barn i samtalegrupper får til å stå fram som selvstendige meningssøkende og meningsskapende subjekter. Problemstilling er: Hvordan blir barns erfaringer håndtert i samtalegrupper for barn som har psykisk syke eller rusavhengige foreldre?Boken er gitt en vitenskapsfilosofisk forankring i en avdekkende hermeneutikk. Dette har lagt føringer for å vektlegge betydningen av det likeverdige og gjensidige i samhandlingene mellom de deltakende barna og de profesjonelle som har ledet samtalegruppene. I den forbindelse er det sentralt å utforske hvordan de profesjonelle, i konkrete samhandlingssituasjoner, skaper rom for det enkelte barns perspektiv ved å sette sine egne perspektiver i spill, og hvordan de ikke gjør det. Den avdekkende hermeneutikken har også gjort det mulig å identifisere noe av det som ikke ble satt ord på, eller som bare så vidt ble antydet eller nevnt, i samhandlingene mellom de profesjonelle og barna, men som likevel kan ha hatt stor betydning for den meningen som ble dannet.Erfaringene og observasjonene fra samtalegruppene er formidlet gjennom ni fortellinger. Disse beskriver konkrete samtaler og aktiviteter der barn formidler egne erfaringer, tanker og følelser, uten at disse blir gjort til videre tema i samhandlingen. Gjennom fortolkning av disse fortellingene kommer det fram en forståelse av at samtalegrupper for barn med psykisk syke eller rusavhengige foreldre synes å være en praksis der barns egne erfaringer av foreldrenes psykiske sykdommer og rusavhengighet i begrenset grad blir gjort til tema. Gjennom en teoretisk diskusjon der det som har foregått i de partikulære samhandlingssituasjonene, blir løftet opp på et mer generelt meningsbærende nivå, er det søkt en dypere forståelse for dette fenomenet.
- Published
- 2020
50. SMIM1 absence is associated with reduced energy expenditure and excess weight
- Author
-
Banasik, Karina, Bay, Jakob, Boldsen, Jens Kjærgaard, Brodersen, Thorsten, Brunak, Søren, Burgdorf, Kristoffer, Chalmer, Mona Ameri, Didriksen, Maria, Dinh, Khoa Manh, Dowsett, Joseph, Erikstrup, Christian, Feenstra, Bjarke, Geller, Frank, Gudbjartsson, Daniel, Hansen, Thomas Folkmann, Hindhede, Lotte, Hjalgrim, Henrik, Jacobsen, Rikke Louise, Jemec, Gregor, Jensen, Bitten Aagaard, Kaspersen, Katrine, Kjerulff, Bertram Dalskov, Kogelman, Lisette, Hørup Larsen, Margit Anita, Louloudis, Ioannis, Lundgaard, Agnete, Susan, Mikkelsen, Christina, Nissen, Ioanna, Nyegaard, Mette, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Henriksen, Alexander Pil, Rohde, Palle Duun, Rostgaard, Klaus, Schwinn, Michael, Stefansson, Kari, Stefánsson, Hreinn, Sørensen, Erik, þorsteinsdóttir, Unnur, Thørner, Lise Wegner, Bruun, Mie Topholm, Ullum, Henrik, Werge, Thomas, Westergaard, David, Chen, Ji, Spracklen, Cassandra N., Marenne, Gaëlle, Varshney, Arushi, Corbin, Laura J., Luan, Jian’an, Willems, Sara M., Wu, Ying, Zhang, Xiaoshuai, Horikoshi, Momoko, Boutin, Thibaud S., Mägi, Reedik, Waage, Johannes, Li-Gao, Ruifang, Katie Chan, Kei Hang, Yao, Jie, Anasanti, Mila D., Chu, Audrey Y., Claringbould, Annique, Heikkinen, Jani, Hong, Jaeyoung, Hottenga, Jouke-Jan, Huo, Shaofeng, Kaakinen, Marika A., Louie, Tin, März, Winfried, Moreno-Macias, Hortensia, Ndungu, Anne, Nelson, Sarah C., Nolte, Ilja M., North, Kari E., Raulerson, Chelsea K., Ray, Debashree, Rohde, Rebecca, Rybin, Denis, Schurmann, Claudia, Sim, Xueling, Southam, Loz, Stewart, Isobel D., Wang, Carol A., Wang, Yujie, Wu, Peitao, Zhang, Weihua, Ahluwalia, Tarunveer S., Appel, Emil V.R., Bielak, Lawrence F., Brody, Jennifer A., Burtt, Noël P., Cabrera, Claudia P., Cade, Brian E., Chai, Jin Fang, Chai, Xiaoran, Chang, Li-Ching, Chen, Chien-Hsiun, Chen, Brian H., Chitrala, Kumaraswamy Naidu, Chiu, Yen-Feng, de Haan, Hugoline G., Delgado, Graciela E., Demirkan, Ayse, Duan, Qing, Engmann, Jorgen, Fatumo, Segun A., Gayán, Javier, Giulianini, Franco, Gong, Jung Ho, Gustafsson, Stefan, Hai, Yang, Hartwig, Fernando P., He, Jing, Heianza, Yoriko, Huang, Tao, Huerta-Chagoya, Alicia, Hwang, Mi Yeong, Jensen, Richard A., Kawaguchi, Takahisa, Kentistou, Katherine A., Kim, Young Jin, Kleber, Marcus E., Kooner, Ishminder K., Lai, Shuiqing, Lange, Leslie A., Langefeld, Carl D., Lauzon, Marie, Li, Man, Ligthart, Symen, Liu, Jun, Loh, Marie, Long, Jirong, Lyssenko, Valeriya, Mangino, Massimo, Marzi, Carola, Montasser, May E., Nag, Abhishek, Nakatochi, Masahiro, Noce, Damia, Noordam, Raymond, Pistis, Giorgio, Preuss, Michael, Raffield, Laura, Rasmussen-Torvik, Laura J., Rich, Stephen S., Robertson, Neil R., Rueedi, Rico, Ryan, Kathleen, Sanna, Serena, Saxena, Richa, Schraut, Katharina E., Sennblad, Bengt, Setoh, Kazuya, Smith, Albert V., Southam, Lorraine, Sparsø, Thomas, Strawbridge, Rona J., Takeuchi, Fumihiko, Tan, Jingyi, Trompet, Stella, van den Akker, Erik, van der Most, Peter J., Verweij, Niek, Vogel, Mandy, Wang, Heming, Wang, Chaolong, Wang, Nan, Warren, Helen R., Wen, Wanqing, Wilsgaard, Tom, Wong, Andrew, Wood, Andrew R., Xie, Tian, Zafarmand, Mohammad Hadi, Zhao, Jing-Hua, Zhao, Wei, Amin, Najaf, Arzumanyan, Zorayr, Astrup, Arne, Bakker, Stephan J.L., Baldassarre, Damiano, Beekman, Marian, Bergman, Richard N., Bertoni, Alain, Blüher, Matthias, Bonnycastle, Lori L., Bornstein, Stefan R., Bowden, Donald W., Cai, Qiuyin, Campbell, Archie, Campbell, Harry, Chang, Yi Cheng, de Geus, Eco J.C., Dehghan, Abbas, Du, Shufa, Eiriksdottir, Gudny, Farmaki, Aliki Eleni, Frånberg, Mattias, Fuchsberger, Christian, Gao, Yutang, Gjesing, Anette P., Goel, Anuj, Han, Sohee, Hartman, Catharina A., Herder, Christian, Hicks, Andrew A., Hsieh, Chang-Hsun, Hsueh, Willa A., Ichihara, Sahoko, Igase, Michiya, Ikram, M. Arfan, Johnson, W. Craig, Jørgensen, Marit E., Joshi, Peter K., Kalyani, Rita R., Kandeel, Fouad R., Katsuya, Tomohiro, Khor, Chiea Chuen, Kiess, Wieland, Kolcic, Ivana, Kuulasmaa, Teemu, Kuusisto, Johanna, Läll, Kristi, Lam, Kelvin, Lawlor, Deborah A., Lee, Nanette R., Lemaitre, Rozenn N., Li, Honglan, Lin, Shih-Yi, Lindström, Jaana, Linneberg, Allan, Liu, Jianjun, Lorenzo, Carlos, Matsubara, Tatsuaki, Matsuda, Fumihiko, Mingrone, Geltrude, Mooijaart, Simon, Moon, Sanghoon, Nabika, Toru, Nadkarni, Girish N., Nadler, Jerry L., Nelis, Mari, Neville, Matt J., Norris, Jill M., Ohyagi, Yasumasa, Peters, Annette, Peyser, Patricia A., Polasek, Ozren, Qi, Qibin, Raven, Dennis, Reilly, Dermot F., Reiner, Alex, Rivideneira, Fernando, Roll, Kathryn, Rudan, Igor, Sabanayagam, Charumathi, Sandow, Kevin, Sattar, Naveed, Schürmann, Annette, Shi, Jinxiu, Stringham, Heather M., Taylor, Kent D., Teslovich, Tanya M., Thuesen, Betina, Timmers, Paul R.H.J., Tremoli, Elena, Tsai, Michael Y., Uitterlinden, Andre, van Dam, Rob M., van Heemst, Diana, van Hylckama Vlieg, Astrid, Van Vliet-Ostaptchouk, Jana V., Vangipurapu, Jagadish, Vestergaard, Henrik, Wang, Tao, Willems van Dijk, Ko, Zemunik, Tatijana, Abecasis, Goncalo R., Adair, Linda S., Aguilar-Salinas, Carlos Alberto, Alarcón-Riquelme, Marta E., An, Ping, Aviles-Santa, Larissa, Becker, Diane M., Beilin, Lawrence J., Bergmann, Sven, Bisgaard, Hans, Black, Corri, Boehnke, Michael, Boerwinkle, Eric, Böhm, Bernhard O., Bønnelykke, Klaus, Boomsma, D.I., Bottinger, Erwin P., Buchanan, Thomas A., Canouil, Mickaël, Caulfield, Mark J., Chambers, John C., Chasman, Daniel I., Ida Chen, Yii-Der, Cheng, Ching-Yu, Collins, Francis S., Correa, Adolfo, Cucca, Francesco, Janaka de Silva, H., Dedoussis, George, Elmståhl, Sölve, Evans, Michele K., Ferrannini, Ele, Ferrucci, Luigi, Florez, Jose C., Franks, Paul W., Frayling, Timothy M., Froguel, Philippe, Gigante, Bruna, Goodarzi, Mark O., Gordon-Larsen, Penny, Grallert, Harald, Grarup, Niels, Grimsgaard, Sameline, Groop, Leif, Gudnason, Vilmundur, Guo, Xiuqing, Hamsten, Anders, Hansen, Torben, Hayward, Caroline, Heckbert, Susan R., Horta, Bernardo L., Huang, Wei, Ingelsson, Erik, James, Pankow S., Jarvelin, Marjo-Ritta, Jonas, Jost B., Jukema, J. Wouter, Kaleebu, Pontiano, Kaplan, Robert, Kardia, Sharon L.R., Kato, Norihiro, Keinanen-Kiukaanniemi, Sirkka M., Kim, Bong-Jo, Kivimaki, Mika, Koistinen, Heikki A., Kooner, Jaspal S., Körner, Antje, Kovacs, Peter, Kuh, Diana, Kumari, Meena, Kutalik, Zoltan, Laakso, Markku, Lakka, Timo A., Launer, Lenore J., Leander, Karin, Li, Huaixing, Lin, Xu, Lind, Lars, Lindgren, Cecilia, Liu, Simin, Loos, Ruth J.F., Magnusson, Patrik K.E., Mahajan, Anubha, Metspalu, Andres, Mook-Kanamori, Dennis O., Mori, Trevor A., Munroe, Patricia B., Njølstad, Inger, O'Connell, Jeffrey R., Oldehinkel, Albertine J., Ong, Ken K., Padmanabhan, Sandosh, Palmer, Colin N.A., Palmer, Nicholette D., Pedersen, Oluf, Pennell, Craig E., Porteous, David J., Pramstaller, Peter P., Province, Michael A., Psaty, Bruce M., Qi, Lu, Raffel, Leslie J., Rauramaa, Rainer, Redline, Susan, Ridker, Paul M., Rosendaal, Frits R., Saaristo, Timo E., Sandhu, Manjinder, Saramies, Jouko, Schneiderman, Neil, Schwarz, Peter, Scott, Laura J., Selvin, Elizabeth, Sever, Peter, Shu, Xiao-Ou, Slagboom, P. Eline, Small, Kerrin S., Smith, Blair H., Snieder, Harold, Sofer, Tamar, Sørensen, Thorkild I.A., Spector, Tim D., Stanton, Alice, Steves, Claire J., Stumvoll, Michael, Sun, Liang, Tabara, Yasuharu, Tai, E. Shyong, Timpson, Nicholas J., Tönjes, Anke, Tuomilehto, Jaakko, Tusie, Teresa, Uusitupa, Matti, van der Harst, Pim, van Duijn, Cornelia, Vitart, Veronique, Vollenweider, Peter, Vrijkotte, Tanja G.M., Wagenknecht, Lynne E., Walker, Mark, Wang, Ya X., Wareham, Nick J., Watanabe, Richard M., Watkins, Hugh, Wei, Wen B., Wickremasinghe, Ananda R., Willemsen, Gonneke, Wilson, James F., Wong, Tien-Yin, Wu, Jer-Yuarn, Xiang, Anny H., Yanek, Lisa R., Yengo, Loïc, Yokota, Mitsuhiro, Zeggini, Eleftheria, Zheng, Wei, Zonderman, Alan B., Rotter, Jerome I., Gloyn, Anna L., McCarthy, Mark I., Dupuis, Josée, Meigs, James B., Scott, Robert A., Prokopenko, Inga, Leong, Aaron, Liu, Ching-Ti, Parker, Stephen C.J., Mohlke, Karen L., Langenberg, Claudia, Wheeler, Eleanor, Morris, Andrew P., Barroso, Inês, Stefanucci, Luca, Moslemi, Camous, Tomé, Ana R., Virtue, Samuel, Bidault, Guillaume, Gleadall, Nicholas S., Watson, Laura P.E., Kwa, Jing E., Burden, Frances, Farrow, Samantha, Võsa, Urmo, Burling, Keith, Walker, Lindsay, Ord, John, Barker, Peter, Warner, James, Frary, Amy, Renhstrom, Karola, Ashford, Sofie E., Piper, Jo, Biggs, Gail, Erber, Wendy N., Hoffman, Gary J., Schoenmakers, Nadia, Rieneck, Klaus, Dziegiel, Morten H., Azzu, Vian, Vacca, Michele, Aparicio, Hugo Javier, Hui, Qin, Cho, Kelly, Sun, Yan V., Wilson, Peter W., Bayraktar, Omer A., Vidal-Puig, Antonio, Ostrowski, Sisse R., Astle, William J., Olsson, Martin L., Storry, Jill R., Pedersen, Ole B., Ouwehand, Willem H., Chatterjee, Krishna, Vuckovic, Dragana, and Frontini, Mattia
- Published
- 2024
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.