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1. Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls

Author: Abel, K., Adamali, H., Adeloye, D., Adeyemi, O., Adrego, R., Aguilar Jimenez, L.A., Ahmad, S., Ahmad Haider, N., Ahmed, R., Ahwireng, N., Ainsworth, M., Al-Sheklly, B., Alamoudi, A., Ali, M., Aljaroof, M., All, A.M., Allan, L., Allen, R.J., Allerton, L., Allsop, L., Almeida, P., Altmann, D., Alvarez Corral, M., Amoils, S., Anderson, D., Antoniades, C., Arbane, G., Arias, A., Armour, C., Armstrong, L., Armstrong, N., Arnold, D., Arnold, H., Ashish, A., Ashworth, A., Ashworth, M., Aslani, S., Assefa-Kebede, H., Atkin, C., Atkin, P., Aul, R., Aung, H., Austin, L., Avram, C., Ayoub, A., Babores, M., Baggott, R., Bagshaw, J., Baguley, D., Bailey, L., Baillie, J.K., Bain, S., Bakali, M., Bakau, M., Baldry, E., Baldwin, D., Baldwin, M., Ballard, C., Banerjee, A., Bang, B., Barker, R.E., Barman, L., Barratt, S., Barrett, F., Basire, D., Basu, N., Bates, M., Bates, A., Batterham, R., Baxendale, H., Bayes, H., Beadsworth, M., Beckett, P., Beggs, M., Begum, M., Beirne, P., Bell, D., Bell, R., Bennett, K., Beranova, E., Bermperi, A., Berridge, A., Berry, C., Betts, S., Bevan, E., Bhui, K., Bingham, M., Birchall, K., Bishop, L., Bisnauthsing, K., Blaikely, J., Bloss, A., Bolger, A., Bolton, C.E., Bonnington, J., Botkai, A., Bourne, C., Bourne, M., Bramham, K., Brear, L., Breen, G., Breeze, J., Briggs, A., Bright, E., Brightling, C.E., Brill, S., Brindle, K., Broad, L., Broadley, A., Brookes, C., Broome, M., Brown, A., Brown, J., Brown, J.S., Brown, M., Brown, V., Brugha, T., Brunskill, N., Buch, M., Buckley, P., Bularga, A., Bullmore, E., Burden, L., Burdett, T., Burn, D., Burns, G., Burns, A., Busby, J., Butcher, R., Butt, A., Byrne, S., Cairns, P., Calder, P.C., Calvelo, E., Carborn, H., Card, B., Carr, C., Carr, L., Carson, G., Carter, P., Casey, A., Cassar, M., Cavanagh, J., Chablani, M., Chalder, T., Chalmers, J.D., Chambers, R.C., Chan, F., Channon, K.M., Chapman, K., Charalambou, A., Chaudhuri, N., Checkley, A., Chen, J., Cheng, Y., Chetham, L., Childs, C., Chilvers, E.R., Chinoy, H., Chiribiri, A., Chong-James, K., Choudhury, G., Choudhury, N., Chowienczyk, P., Christie, C., Chrystal, M., Clark, D., Clark, C., Clarke, J., Clohisey, S., Coakley, G., Coburn, Z., Coetzee, S., Cole, J., Coleman, C., Conneh, F., Connell, D., Connolly, B., Connor, L., Cook, A., Cooper, B., Cooper, J., Cooper, S., Copeland, D., Cosier, T., Coulding, M., Coupland, C., Cox, E., Craig, T., Crisp, P., Cristiano, D., Crooks, M.G., Cross, A., Cruz, I., Cullinan, P., Cuthbertson, D., Daines, L., Dalton, M., Daly, P., Daniels, A., Dark, P., Dasgin, J., David, A., David, C., Davies, E., Davies, F., Davies, G., Davies, G.A., Davies, K., Davies, M.J., Dawson, J., Daynes, E., De Soyza, A., Deakin, B., Deans, A., Deas, C., Deery, J., Defres, S., Dell, A., Dempsey, K., Denneny, E., Dennis, J., Dewar, A., Dharmagunawardena, R., Diar-Bakerly, N., Dickens, C., Dipper, A., Diver, S., Diwanji, S.N., Dixon, M., Djukanovic, R., Dobson, H., Dobson, S.L., Docherty, A.B., Donaldson, A., Dong, T., Dormand, N., Dougherty, A., Dowling, R., Drain, S., Draxlbauer, K., Drury, K., drury, H.J.C., Dulawan, P., Dunleavy, A., Dunn, S., Dupont, C., Earley, J., Easom, N., Echevarria, C., Edwards, S., Edwardson, C., El-Taweel, H., Elliott, A., Elliott, K., Ellis, Y., Elmer, A., Elneima, O., Evans, D., Evans, H., Evans, J., Evans, R., Evans, R.A., Evans, R.I., Evans, T., Evenden, C., Evison, L., Fabbri, L., Fairbairn, S., Fairman, A., Fallon, K., Faluyi, D., Favager, C., Fayzan, T., Featherstone, J., Felton, T., Finch, J., Finney, S., Finnigan, J., Finnigan, L., Fisher, H., Fletcher, S., Flockton, R., Flynn, M., Foot, H., Foote, D., Ford, A., Forton, D., Fraile, E., Francis, C., Francis, R., Francis, S., Frankel, A., Fraser, E., Free, R., French, N., Fu, X., Fuld, J., Furniss, J., Garner, L., Gautam, N., Geddes, J.R., George, J., George, P., Gibbons, M., Gill, M., Gilmour, L., Gleeson, F., Glossop, J., Glover, S., Goodman, N., Goodwin, C., Gooptu, B., Gordon, H., Gorsuch, T., Greatorex, M., Greenhaff, P.L., Greenhalf, W., Greenhalgh, A., Greening, N.J., Greenwood, J., Gregory, H., Gregory, R., Grieve, D., Griffin, D., Griffiths, L., Guerdette, A.-M., Guio, B. 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Weir, Welch, C., Welch, H., Welsh, B., Wessely, S., West, S., Weston, H., Wheeler, H., White, S., Whitehead, V., Whitney, J., Whittaker, S., Whittam, B., Whitworth, V., Wight, A., Wild, J., Wilkins, M., Wilkinson, D., Williams, B., Williams, N., Williams, J., Williams-Howard, S.A., Willicombe, M., Willis, G., Willoughby, J., Wilson, A., Wilson, D., Wilson, I., Window, N., Witham, M., Wolf-Roberts, R., Wood, C., Woodhead, F., Woods, J., Wootton, D.G., Wormleighton, J., Worsley, J., Wraith, D., Brown, C. Wrey, Wright, C., Wright, L., Wright, S., Wyles, J., Wynter, I., Xu, M., Yasmin, N., Yasmin, S., Yates, T., Yip, K.P., Young, B., Young, S., Young, A., Yousuf, A.J., Zawia, A., Zeidan, L., Zhao, B., Zheng, B., Zongo, O., Zheng, Bang, Vivaldi, Giulia, Daines, Luke, Leavy, Olivia C., Richardson, Matthew, Elneima, Omer, McAuley, Hamish J.C., Shikotra, Aarti, Singapuri, Amisha, Sereno, Marco, Saunders, Ruth M., Harris, Victoria C., Houchen-Wolloff, Linzy, Greening, Neil J., Pfeffer, Paul E., Hurst, John R., Brown, Jeremy S., Shankar-Hari, Manu, Echevarria, Carlos, De Soyza, Anthony, Harrison, Ewen M., Docherty, Annemarie B., Lone, Nazir, Quint, Jennifer K., Chalmers, James D., Ho, Ling-Pei, Horsley, Alex, Marks, Michael, Poinasamy, Krishna, Raman, Betty, Heaney, Liam G., Wain, Louise V., Evans, Rachael A., Brightling, Christopher E., Martineau, Adrian, and Sheikh, Aziz
Published: 2023
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2. Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study

Author: Abel, K., Adamali, H., Adeloye, D., Adeyemi, O., Adrego, R., Aguilar Jimenez, L.A., Ahmad, S., Ahmad Haider, N., Ahmed, R., Ahwireng, N., Ainsworth, M., Al-Sheklly, B., Alamoudi, A., Ali, M., Aljaroof, M., All, A.M., Allan, L., Allen, R.J., Allerton, L., Allsop, L., Almeida, P., Altmann, D., Alvarez Corral, M., Amoils, S., Anderson, D., Antoniades, C., Arbane, G., Arias, A., Armour, C., Armstrong, L., Armstrong, N., Arnold, D., Arnold, H., Ashish, A., Ashworth, A., Ashworth, M., Aslani, S., Assefa-Kebede, H., Atkin, C., Atkin, P., Aul, R., Aung, H., Austin, L., Avram, C., Ayoub, A., Babores, M., Baggott, R., Bagshaw, J., Baguley, D., Bailey, L., Baillie, J.K., Bain, S., Bakali, M., Bakau, M., Baldry, E., Baldwin, D., Baldwin, M., Ballard, C., Banerjee, A., Bang, B., Barker, R.E., Barman, L., Barratt, S., Barrett, F., Basire, D., Basu, N., Bates, M., Bates, A., Batterham, R., Baxendale, H., Bayes, H., Beadsworth, M., Beckett, P., Beggs, M., Begum, M., Beirne, P., Bell, D., Bell, R., Bennett, K., Beranova, E., Bermperi, A., Berridge, A., Berry, C., Betts, S., Bevan, E., Bhui, K., Bingham, M., Birchall, K., Bishop, L., Bisnauthsing, K., Blaikely, J., Bloss, A., Bolger, A., Bolton, C.E., Bonnington, J., Botkai, A., Bourne, C., Bourne, M., Bramham, K., Brear, L., Breen, G., Breeze, J., Briggs, A., Bright, E., Brightling, C.E., Brill, S., Brindle, K., Broad, L., Broadley, A., Brookes, C., Broome, M., Brown, A., Brown, J., Brown, J.S., Brown, M., Brown, V., Brugha, T., Brunskill, N., Buch, M., Buckley, P., Bularga, A., Bullmore, E., Burden, L., Burdett, T., Burn, D., Burns, G., Burns, A., Busby, J., Butcher, R., Butt, A., Byrne, S., Cairns, P., Calder, P.C., Calvelo, E., Carborn, H., Card, B., Carr, C., Carr, L., Carson, G., Carter, P., Casey, A., Cassar, M., Cavanagh, J., Chablani, M., Chalder, T., Chalmers, J.D., Chambers, R.C., Chan, F., Channon, K.M., Chapman, K., Charalambou, A., Chaudhuri, N., Checkley, A., Chen, J., Cheng, Y., Chetham, L., Childs, C., Chilvers, E.R., Chinoy, H., Chiribiri, A., Chong-James, K., Choudhury, G., Choudhury, N., Chowienczyk, P., Christie, C., Chrystal, M., Clark, D., Clark, C., Clarke, J., Clohisey, S., Coakley, G., Coburn, Z., Coetzee, S., Cole, J., Coleman, C., Conneh, F., Connell, D., Connolly, B., Connor, L., Cook, A., Cooper, B., Cooper, J., Cooper, S., Copeland, D., Cosier, T., Coulding, M., Coupland, C., Cox, E., Craig, T., Crisp, P., Cristiano, D., Crooks, M.G., Cross, A., Cruz, I., Cullinan, P., Cuthbertson, D., Daines, L., Dalton, M., Daly, P., Daniels, A., Dark, P., Dasgin, J., David, A., David, C., Davies, E., Davies, F., Davies, G., Davies, G.A., Davies, K., Davies, M.J., Dawson, J., Daynes, E., De Soyza, A., Deakin, B., Deans, A., Deas, C., Deery, J., Defres, S., Dell, A., Dempsey, K., Denneny, E., Dennis, J., Dewar, A., Dharmagunawardena, R., Diar-Bakerly, N., Dickens, C., Dipper, A., Diver, S., Diwanji, S.N., Dixon, M., Djukanovic, R., Dobson, H., Dobson, S.L., Docherty, A.B., Donaldson, A., Dong, T., Dormand, N., Dougherty, A., Dowling, R., Drain, S., Draxlbauer, K., Drury, K., Drury, H.J.C., Dulawan, P., Dunleavy, A., Dunn, S., Dupont, C., Earley, J., Easom, N., Echevarria, C., Edwards, S., Edwardson, C., El-Taweel, H., Elliott, A., Elliott, K., Ellis, Y., Elmer, A., Elneima, O., Evans, D., Evans, H., Evans, J., Evans, R., Evans, R.A., Evans, R.I., Evans, T., Evenden, C., Evison, L., Fabbri, L., Fairbairn, S., Fairman, A., Fallon, K., Faluyi, D., Favager, C., Fayzan, T., Featherstone, J., Felton, T., Finch, J., Finney, S., Finnigan, J., Finnigan, L., Fisher, H., Fletcher, S., Flockton, R., Flynn, M., Foot, H., Foote, D., Ford, A., Forton, D., Fraile, E., Francis, C., Francis, R., Francis, S., Frankel, A., Fraser, E., Free, R., French, N., Fu, X., Fuld, J., Furniss, J., Garner, L., Gautam, N., Geddes, J.R., George, J., George, P., Gibbons, M., Gill, M., Gilmour, L., Gleeson, F., Glossop, J., Glover, S., Goodman, N., Goodwin, C., Gooptu, B., Gordon, H., Gorsuch, T., Greatorex, M., Greenhaff, P.L., Greenhalf, W., Greenhalgh, A., Greening, N.J., Greenwood, J., Gregory, H., Gregory, R., Grieve, D., Griffin, D., Griffiths, L., Guerdette, A.-M., Guillen Guio, B., Gummadi, M., Gupta, A., Gurram, S., Guthrie, E., Guy, Z., Henson, H.H., Hadley, K., Haggar, A., Hainey, K., Hairsine, B., Haldar, P., Hall, I., Hall, L., Halling-Brown, M., Hamil, R., Hancock, A., Hancock, K., Hanley, N.A., Haq, S., Hardwick, H.E., Hardy, E., Hardy, T., Hargadon, B., Harrington, K., Harris, E., Harris, V.C., Harrison, E.M., Harrison, P., Hart, N., Harvey, A., Harvey, M., Harvie, M., Haslam, L., Havinden-Williams, M., Hawkes, J., Hawkings, N., Haworth, J., Hayday, A., Haynes, M., Hazeldine, J., Hazelton, T., Heaney, L.G., Heeley, C., Heeney, J.L., Heightman, M., Heller, S., Henderson, M., Hesselden, L., Hewitt, M., Highett, V., Hillman, T., Hiwot, T., Ho, L.P., Hoare, A., Hoare, M., Hockridge, J., Hogarth, P., Holbourn, A., Holden, S., Holdsworth, L., Holgate, D., Holland, M., 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Published: 2023
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3. SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

Author: Baillie, J. Kenneth, Openshaw, Peter J.M., Semple, Malcolm G., Alex, Beatrice, Andrikopoulos, Petros, Bach, Benjamin, Barclay, Wendy S., Bogaert, Debby, Chand, Meera, Chechi, Kanta, Cooke, Graham S., da Silva Filipe, Ana, de Silva, Thushan, Docherty, Annemarie B., dos Santos Correia, Gonçalo, Dumas, Marc-Emmanuel, Dunning, Jake, Fletcher, Tom, Green, Christopher A., Greenhalf, William, Griffin, Julian, Gupta, Rishi K., Harrison, Ewen M., Ho, Antonia Y.W., Holden, Karl, Horby, Peter W., Ijaz, Samreen, Khoo, Say, Klenerman, Paul, Law, Andrew, Lewis, Matthew, Liggi, Sonia, Lim, Wei Shen, Maslen, Lynn, Mentzer, Alexander J., Merson, Laura, Meynert, Alison M, Moore, Shona C., Noursadeghi, Mahdad, Olanipekun, Michael, Osagie, Anthonia, Palmarini, Massimo, Palmieri, Carlo, Paxton, William A., Pollakis, Georgios, Price, Nicholas, Rambaut, Andrew, Robertson, David L, Russell, Clark D., Sancho-Shimizu, Vanessa, Sands, Caroline, Scott, Janet T., Sigfrid, Louise, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Summers, Charlotte, Swann, Olivia V., Takats, Zoltan, Takis, Panteleimon, Tedder, Richard S., Thompson, A.A. 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A., Batterham, R., Baxendale, H., Bayes, H., Beadsworth, M., Beckett, P., Beggs, M., Begum, M., Beirne, P., Bell, D., Bell, R., Bennett, K., Beranova, E., Bermperi, A., Berridge, A., Berry, C., Betts, S., Bevan, E., Bhui, K., Bingham, M., Birchall, K., Bishop, L., Bisnauthsing, K., Blaikely, J., Bloss, A., Bolger, A., Bolton, C.E., Bonnington, J., Botkai, A., Bourne, C., Bourne, M., Bramham, K., Brear, L., Breen, G., Breeze, J., Briggs, A., Bright, E., Brightling, C.E., Brill, S., Brindle, K., Broad, L., Broadley, A., Brookes, C., Broome, M., Brown, A., Brown, J., Brown, J.S., Brown, M., Brown, V., Brugha, T., Brunskill, N., Buch, M., Buckley, P., Bularga, A., Bullmore, E., Burden, L., Burdett, T., Burn, D., Burns, G., Burns, A., Busby, J., Butcher, R., Butt, A., Byrne, S., Cairns, P., Calder, P.C., Calvelo, E., Carborn, H., Card, B., Carr, C., Carr, L., Carson, G., Carter, P., Casey, A., Cassar, M., Cavanagh, J., Chablani, M., Chalder, T., Chalmers, J.D., Chambers, R.C., Chan, F., 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Gleeson, F., Glossop, J., Glover, S., Goodman, N., Goodwin, C., Gooptu, B., Gordon, H., Gorsuch, T., Greatorex, M., Greenhaff, P.L., Greenhalf, W., Greenhalgh, A., Greening, N.J., Greenwood, J., Gregory, H., Gregory, R., Grieve, D., Griffin, D., Griffiths, L., Guerdette, A-M., Guillen Guio, B., Gummadi, M., Gupta, A., Gurram, S., Guthrie, E., Guy, Z., H Henson, H., Hadley, K., Haggar, A., Hainey, K., Hairsine, B., Haldar, P., Hall, I., Hall, L., Halling-Brown, M., Hamil, R., Hancock, A., Hancock, K., Hanley, N.A., Haq, S., Hardwick, H.E., Hardy, E., Hardy, T., Hargadon, B., Harrington, K., Harris, E., Harris, V.C., Harrison, E.M., Harrison, P., Hart, N., Harvey, A., Harvey, M., Harvie, M., Haslam, L., Havinden-Williams, M., Hawkes, J., Hawkings, N., Haworth, J., Hayday, A., Haynes, M., Hazeldine, J., Hazelton, T., Heaney, L.G., Heeley, C., Heeney, J.L., Heightman, M., Heller, S., Henderson, M., Hesselden, L., Hewitt, M., Highett, V., Hillman, T., Hiwot, T., Ho, L.P., Hoare, A., Hoare, 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Kingham, L., Kirk, J., Kitterick, P., Klenerman, P., Knibbs, L., Knight, S., Knighton, A., Kon, O., Kon, S., Kon, S.S., Koprowska, S., Korszun, A., Koychev, I., Kurasz, C., Kurupati, P., Laing, C., Lamlum, H., Landers, G., Langenberg, C., Lasserson, D., Lavelle-Langham, L., Lawrie, A., Lawson, C., Layton, A., Lea, A., Leavy, O.C., Lee, D., Lee, J-H., Lee, E., Leitch, K., Lenagh, R., Lewis, D., Lewis, J., Lewis, K.E., Lewis, V., Lewis-Burke, N., Li, X., Light, T., Lightstone, L., Lilaonitkul, W., Lim, L., Linford, S., Lingford-Hughes, A., Lipman, M., Liyanage, K., Lloyd, A., Logan, S., Lomas, D., Lone, N.I., Loosley, R., Lord, J.M., Lota, H., Lovegrove, W., Lucey, A., Lukaschuk, E., Lye, A., Lynch, C., MacDonald, S., MacGowan, G., Macharia, I., Mackie, J., Macliver, L., Madathil, S., Madzamba, G., Magee, N., Magtoto, M.M., Mairs, N., Majeed, N., Major, E., Malein, F., Malim, M., Mallison, G., Man, W.D.-C., Mandal, S., Mangion, K., Manisty, C., Manley, R., March, K., Marciniak, S., Marino, P., Mariveles, M., Marks, M., Marouzet, E., Marsh, S., Marshall, B., Marshall, M., Martin, J., Martineau, A., Martinez, L.M., Maskell, N., Matila, D., Matimba-Mupaya, W., Matthews, L., Mbuyisa, A., McAdoo, S., McAllister-Williams, H., McArdle, A., McArdle, P., McAulay, D., McCann, G.P., drury, H.J.C., McCormick, J., McCormick, W., McCourt, P., McGarvey, L., McGee, C., Mcgee, K., McGinness, J., McGlynn, K., McGovern, A., McGuinness, H., McInnes, I.B., McIntosh, J., McIvor, E., McIvor, K., McLeavey, L., McMahon, A., McMahon, M.J., McMorrow, L., Mcnally, T., McNarry, M., McNeill, J., McQueen, A., McShane, H., Mears, C., Megson, C., Megson, S., Mehta, P., Meiring, J., Melling, L., Mencias, M., Menzies, D., Merida Morillas, M., Michael, A., Miller, C., Milligan, L., Mills, C., Mills, N.L., Milner, L., Misra, S., Mitchell, J., Mohamed, A., Mohamed, N., Mohammed, S., Molyneaux, P.L., Monteiro, W., Moriera, S., Morley, A., Morrison, L., Morriss, R., Morrow, A., Moss, A.J., Moss, P., 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Zhao, B., Zheng, B., Zongo, O., Liew, Felicity, Talwar, Shubha, Cross, Andy, Willett, Brian J., Scott, Sam, Logan, Nicola, Siggins, Matthew K., Swieboda, Dawid, Sidhu, Jasmin K., Efstathiou, Claudia, Davis, Chris, Mohamed, Noura, Nunag, Jose, King, Clara, Rowland-Jones, Sarah L., Chalmers, James D., Ho, Ling-Pei, Horsley, Alexander, Raman, Betty, Poinasamy, Krisnah, Marks, Michael, Kon, Onn Min, Howard, Luke, Wootton, Daniel G., Dunachie, Susanna, Quint, Jennifer K., Evans, Rachael A., Wain, Louise V., Fontanella, Sara, de Silva, Thushan I., Ho, Antonia, Harrison, Ewen, Brightling, Christopher, and Turtle, Lance
Published: 2023
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4. Age-related changes in muscle architecture and metabolism in humans: The likely contribution of physical inactivity to age-related functional decline

Author: Shur, N.F., Creedon, L., Skirrow, S., Atherton, P.J., MacDonald, I.A., Lund, J., and Greenhaff, P.L.
Published: 2021
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5. Maximal-intensity exercise does not fully restore muscle pyruvate dehydrogenase complex activation after 3 days of high-fat dietary intake

Author: Constantin-Teodosiu, D., Cederblad, G., Bergström, M., and Greenhaff, P.L.
Published: 2019
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6. Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study

Author: McAuley, Hamish J.C., primary, Evans, Rachael A., additional, Bolton, Charlotte E., additional, Brightling, Christopher E., additional, Chalmers, James D., additional, Docherty, Annemarie B., additional, Elneima, Omer, additional, Greenhaff, Paul L., additional, Gupta, Ayushman, additional, Harris, Victoria C., additional, Harrison, Ewen M., additional, Ho, Ling-Pei, additional, Horsley, Alex, additional, Houchen-Wolloff, Linzy, additional, Jolley, Caroline J., additional, Leavy, Olivia C., additional, Lone, Nazir I., additional, Man, William D-C, additional, Marks, Michael, additional, Parekh, Dhruv, additional, Poinasamy, Krisnah, additional, Quint, Jennifer K., additional, Raman, Betty, additional, Richardson, Matthew, additional, Saunders, Ruth M., additional, Sereno, Marco, additional, Shikotra, Aarti, additional, Singapuri, Amisha, additional, Singh, Sally J., additional, Steiner, Michael, additional, Tan, Ai Lyn, additional, Wain, Louise V., additional, Welch, Carly, additional, Whitney, Julie, additional, Witham, Miles D., additional, Lord, Janet, additional, Greening, Neil J., additional, Abel, K., additional, Adamali, H., additional, Adeloye, D., additional, Adeyemi, O., additional, Adrego, R., additional, Aguilar Jimenez, L.A., additional, Ahmad, S., additional, Ahmad Haider, N., additional, Ahmed, R., additional, Ahwireng, N., additional, Ainsworth, M., additional, Al-Sheklly, B., additional, Alamoudi, A., additional, Ali, M., additional, Aljaroof, M., additional, All, A.M., additional, Allan, L., additional, Allen, R.J., additional, Allerton, L., additional, Allsop, L., additional, Almeida, P., additional, Altmann, D., additional, Alvarez Corral, M., additional, Amoils, S., additional, Anderson, D., additional, Antoniades, C., additional, Arbane, G., additional, Arias, A., additional, Armour, C., additional, Armstrong, L., additional, Armstrong, N., additional, Arnold, D., additional, Arnold, H., additional, Ashish, A., additional, Ashworth, A., additional, Ashworth, M., additional, Aslani, S., additional, Assefa-Kebede, H., additional, Atkin, C., additional, Atkin, P., additional, Aul, R., additional, Aung, H., additional, Austin, L., additional, Avram, C., additional, Ayoub, A., additional, Babores, M., additional, Baggott, R., additional, Bagshaw, J., additional, Baguley, D., additional, Bailey, L., additional, Baillie, J.K., additional, Bain, S., additional, Bakali, M., additional, Bakau, M., additional, Baldry, E., additional, Baldwin, D., additional, Baldwin, M., additional, Ballard, C., additional, Banerjee, A., additional, Bang, B., additional, Barker, R.E., additional, Barman, L., additional, Barratt, S., additional, Barrett, F., additional, Basire, D., additional, Basu, N., additional, Bates, M., additional, Bates, A., additional, Batterham, R., additional, Baxendale, H., additional, Bayes, H., additional, Beadsworth, M., additional, Beckett, P., additional, Beggs, M., additional, Begum, M., additional, Beirne, P., additional, Bell, D., additional, Bell, R., additional, Bennett, K., additional, Beranova, E., additional, Bermperi, A., additional, Berridge, A., additional, Berry, C., additional, Betts, S., additional, Bevan, E., additional, Bhui, K., additional, Bingham, M., additional, Birchall, K., additional, Bishop, L., additional, Bisnauthsing, K., additional, Blaikely, J., additional, Bloss, A., additional, Bolger, A., additional, Bolton, C.E., additional, Bonnington, J., additional, Botkai, A., additional, Bourne, C., additional, Bourne, M., additional, Bramham, K., additional, Brear, L., additional, Breen, G., additional, Breeze, J., additional, Briggs, A., additional, Bright, E., additional, Brightling, C.E., additional, Brill, S., additional, Brindle, K., additional, Broad, L., additional, Broadley, A., additional, Brookes, C., additional, Broome, M., additional, Brown, A., additional, Brown, J., additional, Brown, J.S., additional, Brown, M., additional, Brown, V., additional, Brugha, T., additional, Brunskill, N., additional, Buch, M., additional, Buckley, P., additional, Bularga, A., additional, Bullmore, E., additional, Burden, L., additional, Burdett, T., additional, Burn, D., additional, Burns, G., additional, Burns, A., additional, Busby, J., additional, Butcher, R., additional, Butt, A., additional, Byrne, S., additional, Cairns, P., additional, Calder, P.C., additional, Calvelo, E., additional, Carborn, H., additional, Card, B., additional, Carr, C., additional, Carr, L., additional, Carson, G., additional, Carter, P., additional, Casey, A., additional, Cassar, M., additional, Cavanagh, J., additional, Chablani, M., additional, Chalder, T., additional, Chalmers, J.D., additional, Chambers, R.C., additional, Chan, F., additional, Channon, K.M., additional, Chapman, K., additional, Charalambou, A., additional, Chaudhuri, N., additional, Checkley, A., additional, Chen, J., additional, Cheng, Y., additional, Chetham, L., additional, Childs, C., additional, Chilvers, E.R., additional, Chinoy, H., additional, Chiribiri, A., additional, Chong-James, K., additional, Choudhury, G., additional, Choudhury, N., additional, Chowienczyk, P., additional, Christie, C., additional, Chrystal, M., additional, Clark, D., additional, Clark, C., additional, Clarke, J., additional, Clohisey, S., additional, Coakley, G., additional, Coburn, Z., additional, Coetzee, S., additional, Cole, J., additional, Coleman, C., additional, Conneh, F., additional, Connell, D., additional, Connolly, B., additional, Connor, L., additional, Cook, A., additional, Cooper, B., additional, Cooper, J., additional, Cooper, S., additional, Copeland, D., additional, Cosier, T., additional, Coulding, M., additional, Coupland, C., additional, Cox, E., additional, Craig, T., additional, Crisp, P., additional, Cristiano, D., additional, Crooks, M.G., additional, Cross, A., additional, Cruz, I., additional, Cullinan, P., additional, Cuthbertson, D., additional, Daines, L., additional, Dalton, M., additional, Daly, P., additional, Daniels, A., additional, Dark, P., additional, Dasgin, J., additional, David, A., additional, David, C., additional, Davies, E., additional, Davies, F., additional, Davies, G., additional, Davies, G.A., additional, Davies, K., additional, Davies, M.J., additional, Dawson, J., additional, Daynes, E., additional, De Soyza, A., additional, Deakin, B., additional, Deans, A., additional, Deas, C., additional, Deery, J., additional, Defres, S., additional, Dell, A., additional, Dempsey, K., additional, Denneny, E., additional, Dennis, J., additional, Dewar, A., additional, Dharmagunawardena, R., additional, Diar-Bakerly, N., additional, Dickens, C., additional, Dipper, A., additional, Diver, S., additional, Diwanji, S.N., additional, Dixon, M., additional, Djukanovic, R., additional, Dobson, H., additional, Dobson, S.L., additional, Docherty, A.B., additional, Donaldson, A., additional, Dong, T., additional, Dormand, N., additional, Dougherty, A., additional, Dowling, R., additional, Drain, S., additional, Draxlbauer, K., additional, Drury, K., additional, Drury, H.J.C., additional, Dulawan, P., additional, Dunleavy, A., additional, Dunn, S., additional, Dupont, C., additional, Earley, J., additional, Easom, N., additional, Echevarria, C., additional, Edwards, S., additional, Edwardson, C., additional, El-Taweel, H., additional, Elliott, A., additional, Elliott, K., additional, Ellis, Y., additional, Elmer, A., additional, Elneima, O., additional, Evans, D., additional, Evans, H., additional, Evans, J., additional, Evans, R., additional, Evans, R.A., additional, Evans, R.I., additional, Evans, T., additional, Evenden, C., additional, Evison, L., additional, Fabbri, L., additional, Fairbairn, S., additional, Fairman, A., additional, Fallon, K., additional, Faluyi, D., additional, Favager, C., additional, Fayzan, T., additional, Featherstone, J., additional, Felton, T., additional, Finch, J., additional, Finney, S., additional, Finnigan, J., additional, Finnigan, L., additional, Fisher, H., additional, Fletcher, S., additional, Flockton, R., additional, Flynn, M., additional, Foot, H., additional, Foote, D., additional, Ford, A., additional, Forton, D., additional, Fraile, E., additional, Francis, C., additional, Francis, R., additional, Francis, S., additional, Frankel, A., additional, Fraser, E., additional, Free, R., additional, French, N., additional, Fu, X., additional, Fuld, J., additional, Furniss, J., additional, Garner, L., additional, Gautam, N., additional, Geddes, J.R., additional, George, J., additional, George, P., additional, Gibbons, M., additional, Gill, M., additional, Gilmour, L., additional, Gleeson, F., additional, Glossop, J., additional, Glover, S., additional, Goodman, N., additional, Goodwin, C., additional, Gooptu, B., additional, Gordon, H., additional, Gorsuch, T., additional, Greatorex, M., additional, Greenhaff, P.L., additional, Greenhalf, W., additional, Greenhalgh, A., additional, Greening, N.J., additional, Greenwood, J., additional, Gregory, H., additional, Gregory, R., additional, Grieve, D., additional, Griffin, D., additional, Griffiths, L., additional, Guerdette, A.-M., additional, Guillen Guio, B., additional, Gummadi, M., additional, Gupta, A., additional, Gurram, S., additional, Guthrie, E., additional, Guy, Z., additional, Henson, H.H., additional, Hadley, K., additional, Haggar, A., additional, Hainey, K., additional, Hairsine, B., additional, Haldar, P., additional, Hall, I., additional, Hall, L., additional, Halling-Brown, M., additional, Hamil, R., additional, Hancock, A., additional, Hancock, K., additional, Hanley, N.A., additional, Haq, S., additional, Hardwick, H.E., additional, Hardy, E., additional, Hardy, T., additional, Hargadon, B., additional, Harrington, K., additional, Harris, E., additional, Harris, V.C., additional, Harrison, E.M., additional, Harrison, P., additional, Hart, N., additional, Harvey, A., additional, 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additional, Hotopf, M., additional, Houchen-Wolloff, L., additional, Howard, K., additional, Howard, L.S., additional, Howell, A., additional, Hufton, E., additional, Hughes, A.D., additional, Hughes, J., additional, Hughes, R., additional, Humphries, A., additional, Huneke, N., additional, Hurditch, E., additional, Hurst, J., additional, Husain, M., additional, Hussell, T., additional, Hutchinson, J., additional, Ibrahim, W., additional, Ilyas, F., additional, Ingham, J., additional, Ingram, L., additional, Ionita, D., additional, Isaacs, K., additional, Ismail, K., additional, Jackson, T., additional, Jacob, J., additional, James, W.Y., additional, Jang, W., additional, Jarman, C., additional, Jarrold, I., additional, Jarvis, H., additional, Jastrub, R., additional, Jayaraman, B., additional, Jenkins, R.G., additional, Jezzard, P., additional, Jiwa, K., additional, Johnson, C., additional, Johnson, S., additional, Johnston, D., additional, Jolley, C.J., additional, Jones, D., additional, Jones, G., additional, Jones, H., additional, Jones, I., additional, Jones, L., additional, Jones, M.G., additional, Jones, S., additional, Jose, S., additional, Kabir, T., additional, Kaltsakas, G., additional, Kamwa, V., additional, Kanellakis, N., additional, Kaprowska, S., additional, Kausar, Z., additional, Keenan, N., additional, Kelly, S., additional, Kemp, G., additional, Kerr, S., additional, Kerslake, H., additional, Key, A.L., additional, Khan, F., additional, Khunti, K., additional, Kilroy, S., additional, King, B., additional, King, C., additional, Kingham, L., additional, Kirk, J., additional, Kitterick, P., additional, Klenerman, P., additional, Knibbs, L., additional, Knight, S., additional, Knighton, A., additional, Kon, O., additional, Kon, S., additional, Kon, S.S., additional, Koprowska, S., additional, Korszun, A., additional, Koychev, I., additional, Kurasz, C., additional, Kurupati, P., additional, Laing, C., additional, Lamlum, H., additional, Landers, G., additional, Langenberg, C., additional, Lasserson, D., additional, Lavelle-Langham, L., additional, Lawrie, A., additional, Lawson, C., additional, Layton, A., additional, Lea, A., additional, Leavy, O.C., additional, Lee, D., additional, Lee, J.-H., additional, Lee, E., additional, Leitch, K., additional, Lenagh, R., additional, Lewis, D., additional, Lewis, J., additional, Lewis, K.E., additional, Lewis, V., additional, Lewis-Burke, N., additional, Li, X., additional, Light, T., additional, Lightstone, L., additional, Lilaonitkul, W., additional, Lim, L., additional, Linford, S., additional, Lingford-Hughes, A., additional, Lipman, M., additional, Liyanage, K., additional, Lloyd, A., additional, Logan, S., additional, Lomas, D., additional, Lone, N.I., additional, Loosley, R., additional, Lord, J.M., additional, Lota, H., additional, Lovegrove, W., additional, Lucey, A., additional, Lukaschuk, E., additional, Lye, A., additional, Lynch, C., additional, MacDonald, S., additional, MacGowan, G., additional, Macharia, I., additional, Mackie, J., additional, Macliver, L., additional, Madathil, S., additional, Madzamba, G., additional, Magee, N., additional, Magtoto, M.M., additional, Mairs, N., additional, Majeed, N., additional, Major, E., additional, Malein, F., additional, Malim, M., additional, Mallison, G., additional, D-C Man, W., additional, Mandal, S., additional, Mangion, K., additional, Manisty, C., additional, Manley, R., additional, March, K., additional, Marciniak, S., additional, Marino, P., additional, Mariveles, M., additional, Marks, M., additional, Marouzet, E., additional, Marsh, S., additional, Marshall, B., additional, Marshall, M., additional, Martin, J., additional, Martineau, A., additional, Martinez, L.M., additional, Maskell, N., additional, Matila, D., additional, Matimba-Mupaya, W., additional, Matthews, L., additional, Mbuyisa, A., additional, McAdoo, S., additional, McAllister-Williams, H., additional, McArdle, A., additional, McArdle, P., additional, McAulay, D., additional, McCann, G.P., additional, McCormick, J., additional, McCormick, W., additional, McCourt, P., additional, McGarvey, L., additional, McGee, C., additional, Mcgee, K., additional, McGinness, J., additional, McGlynn, K., additional, McGovern, A., additional, McGuinness, H., additional, McInnes, I.B., additional, McIntosh, J., additional, McIvor, E., additional, McIvor, K., additional, McLeavey, L., additional, McMahon, A., additional, McMahon, M.J., additional, McMorrow, L., additional, Mcnally, T., additional, McNarry, M., additional, McNeill, J., additional, McQueen, A., additional, McShane, H., additional, Mears, C., additional, Megson, C., additional, Megson, S., additional, Mehta, P., additional, Meiring, J., additional, Melling, L., additional, Mencias, M., additional, Menzies, D., additional, Merida Morillas, M., additional, Michael, A., additional, Miller, C., additional, Milligan, L., additional, Mills, C., additional, Mills, G., additional, Mills, N.L., additional, Milner, L., additional, Misra, S., additional, Mitchell, J., additional, Mohamed, A., additional, Mohamed, N., additional, Mohammed, S., additional, Molyneaux, P.L., additional, Monteiro, W., additional, Moriera, S., additional, Morley, A., additional, Morrison, L., additional, Morriss, R., additional, Morrow, A., additional, Moss, A.J., additional, Moss, P., additional, Motohashi, K., additional, Msimanga, N., additional, Mukaetova-Ladinska, E., additional, Munawar, U., additional, Murira, J., additional, Nanda, U., additional, Nassa, H., additional, Nasseri, M., additional, Neal, A., additional, Needham, R., additional, Neill, P., additional, Neubauer, S., additional, Newby, D.E., additional, Newell, H., additional, Newman, T., additional, Newman, J., additional, Newton-Cox, A., additional, Nicholson, T., additional, Nicoll, D., additional, Nikolaidis, A., additional, Nolan, C.M., additional, Noonan, M.J., additional, Norman, C., 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additional, Ross, A., additional, Ross, G., additional, Rossdale, J., additional, Rostron, A., additional, Rowe, A., additional, Rowland, A., additional, Rowland, J., additional, Rowland, M.J., additional, Rowland-Jones, S.L., additional, Roy, K., additional, Roy, M., additional, Rudan, I., additional, Russell, R., additional, Russell, E., additional, Saalmink, G., additional, Sabit, R., additional, Sage, E.K., additional, Samakomva, T., additional, Samani, N., additional, Sampson, C., additional, Samuel, K., additional, Samuel, R., additional, Sanderson, A., additional, Sapey, E., additional, Saralaya, D., additional, Sargant, J., additional, Sarginson, C., additional, Sass, T., additional, Sattar, N., additional, Saunders, K., additional, Saunders, R.M., additional, Saunders, P., additional, Saunders, L.C., additional, Savill, H., additional, Saxon, W., additional, Sayer, A., additional, Schronce, J., additional, Schwaeble, W., additional, Scott, J.T., additional, Scott, K., additional, Selby, N., additional, Semple, M.G., additional, Sereno, M., additional, Sewell, T.A., additional, Shah, A., additional, Shah, K., additional, Shah, P., additional, Shankar-Hari, M., additional, Sharma, M., additional, Sharpe, C., additional, Sharpe, M., additional, Shashaa, S., additional, Shaw, A., additional, Shaw, K., additional, Shaw, V., additional, Sheikh, A., additional, Shelton, S., additional, Shenton, L., additional, Shevket, K., additional, Shikotra, A., additional, Short, J., additional, Siddique, S., additional, Siddiqui, S., additional, Sidebottom, J., additional, Sigfrid, L., additional, Simons, G., additional, Simpson, J., additional, Simpson, N., additional, Singapuri, A., additional, Singh, C., additional, Singh, S., additional, Singh, S.J., additional, Sissons, D., additional, Skeemer, J., additional, Slack, K., additional, Smith, A., additional, Smith, D., additional, Smith, S., additional, Smith, J., additional, Smith, L., additional, Soares, M., 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Yip, K.P., additional, Young, B., additional, Young, S., additional, Young, A., additional, Yousuf, A.J., additional, Zawia, A., additional, Zeidan, L., additional, Zhao, B., additional, Zheng, B., additional, and Zongo, O., additional
Published: 2023
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7. SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

Author: Liew, Felicity, primary, Talwar, Shubha, additional, Cross, Andy, additional, Willett, Brian J., additional, Scott, Sam, additional, Logan, Nicola, additional, Siggins, Matthew K., additional, Swieboda, Dawid, additional, Sidhu, Jasmin K., additional, Efstathiou, Claudia, additional, Moore, Shona C., additional, Davis, Chris, additional, Mohamed, Noura, additional, Nunag, Jose, additional, King, Clara, additional, Thompson, A.A. Roger, additional, Rowland-Jones, Sarah L., additional, Docherty, Annemarie B., additional, Chalmers, James D., additional, Ho, Ling-Pei, additional, Horsley, Alexander, additional, Raman, Betty, additional, Poinasamy, Krisnah, additional, Marks, Michael, additional, Kon, Onn Min, additional, Howard, Luke, additional, Wootton, Daniel G., additional, Dunachie, Susanna, additional, Quint, Jennifer K., additional, Evans, Rachael A., additional, Wain, Louise V., additional, Fontanella, Sara, additional, de Silva, Thushan I., additional, Ho, Antonia, additional, Harrison, Ewen, additional, Baillie, J. Kenneth, additional, Semple, Malcolm G., additional, Brightling, Christopher, additional, Thwaites, Ryan S., additional, Turtle, Lance, additional, Openshaw, Peter J.M., additional, Alex, Beatrice, additional, Andrikopoulos, Petros, additional, Bach, Benjamin, additional, Barclay, Wendy S., additional, Bogaert, Debby, additional, Chand, Meera, additional, Chechi, Kanta, additional, Cooke, Graham S., additional, da Silva Filipe, Ana, additional, de Silva, Thushan, additional, dos Santos Correia, Gonçalo, additional, Dumas, Marc-Emmanuel, additional, Dunning, Jake, additional, Fletcher, Tom, additional, Green, Christopher A., additional, Greenhalf, William, additional, Griffin, Julian, additional, Gupta, Rishi K., additional, Harrison, Ewen M., additional, Ho, Antonia Y.W., additional, Holden, Karl, additional, Horby, Peter W., additional, Ijaz, Samreen, additional, Khoo, Say, additional, Klenerman, Paul, additional, Law, Andrew, additional, Lewis, Matthew, additional, Liggi, Sonia, additional, Lim, Wei Shen, additional, Maslen, Lynn, additional, Mentzer, Alexander J., additional, Merson, Laura, additional, Meynert, Alison M, additional, Noursadeghi, Mahdad, additional, Olanipekun, Michael, additional, Osagie, Anthonia, additional, Palmarini, Massimo, additional, Palmieri, Carlo, additional, Paxton, William A., additional, Pollakis, Georgios, additional, Price, Nicholas, additional, Rambaut, Andrew, additional, Robertson, David L, additional, Russell, Clark D., additional, Sancho-Shimizu, Vanessa, additional, Sands, Caroline, additional, Scott, Janet T., additional, Sigfrid, Louise, additional, Solomon, Tom, additional, Sriskandan, Shiranee, additional, Stuart, David, additional, Summers, Charlotte, additional, Swann, Olivia V., additional, Takats, Zoltan, additional, Takis, Panteleimon, additional, Tedder, Richard S., additional, Thomson, Emma C., additional, Turtle, Lance C.W., additional, Zambon, Maria, additional, Drake, Thomas M., additional, Fairfield, Cameron J., additional, Knight, Stephen R., additional, Mclean, Kenneth A., additional, Murphy, Derek, additional, Norman, Lisa, additional, Pius, Riinu, additional, Shaw, Catherine A., additional, Connor, Marie, additional, Dalton, Jo, additional, Gamble, Carrol, additional, Girvan, Michelle, additional, Halpin, Sophie, additional, Harrison, Janet, additional, Jackson, Clare, additional, Lee, James, additional, Marsh, Laura, additional, Plotkin, Daniel, additional, Roberts, Stephanie, additional, Saviciute, Egle, additional, Clohisey, Sara, additional, Hendry, Ross, additional, Knight, Susan, additional, Lahnsteiner, Eva, additional, Leeming, Gary, additional, Norris, Lucy, additional, Scott-Brown, James, additional, Tait, Sarah, additional, Wham, Murray, additional, Clark, Richard, additional, Coutts, Audrey, additional, Donelly, Lorna, additional, Fawkes, Angie, additional, Gilchrist, Tammy, additional, Hafezi, Katarzyna, additional, MacGillivray, Louise, additional, Maclean, Alan, additional, McCafferty, Sarah, additional, Morrice, Kirstie, additional, Murphy, Lee, additional, Wrobel, Nicola, additional, Carson, Gail, additional, Adeniji, Kayode, additional, Agranoff, Daniel, additional, Agwuh, Ken, additional, Ail, Dhiraj, additional, Aldera, Erin L., additional, Alegria, Ana, additional, Allen, Sam, additional, Angus, Brian, additional, Ashish, Abdul, additional, Atkinson, Dougal, additional, Bari, Shahedal, additional, Barlow, Gavin, additional, Barnass, Stella, additional, Barrett, Nicholas, additional, Bassford, Christopher, additional, Basude, Sneha, additional, Baxter, David, additional, Beadsworth, Michael, additional, Bernatoniene, Jolanta, additional, Berridge, John, additional, Berry, Colin, additional, Best, Nicola, additional, Bothma, Pieter, additional, Brittain-Long, Robin, additional, Bulteel, Naomi, additional, Burden, Tom, additional, Burtenshaw, Andrew, additional, Caruth, Vikki, additional, Chadwick, David, additional, Chambler, Duncan, additional, Chee, Nigel, additional, Child, Jenny, additional, Chukkambotla, Srikanth, additional, Clark, Tom, additional, Collini, Paul, additional, Cosgrove, Catherine, additional, Cupitt, Jason, additional, Cutino-Moguel, Maria-Teresa, additional, Dark, Paul, additional, Dawson, Chris, additional, Dervisevic, Samir, additional, Donnison, Phil, additional, Douthwaite, Sam, additional, Drummond, Andrew, additional, DuRand, Ingrid, additional, Dushianthan, Ahilanadan, additional, Dyer, Tristan, additional, Evans, Cariad, additional, Eziefula, Chi, additional, Fegan, Chrisopher, additional, Finn, Adam, additional, Fullerton, Duncan, additional, Garg, Sanjeev, additional, Garg, Atul, additional, Gkrania-Klotsas, Effrossyni, additional, Godden, Jo, additional, Goldsmith, Arthur, additional, Graham, Clive, additional, Grammatikopoulos, Tassos, additional, Hardy, Elaine, additional, Hartshorn, Stuart, additional, Harvey, Daniel, additional, Havalda, Peter, additional, Hawcutt, Daniel B., additional, Hobrok, Maria, additional, Hodgson, Luke, additional, Hormis, Anil, additional, Howard, Joanne, additional, Jacobs, Michael, additional, Jain, Susan, additional, Jennings, Paul, additional, Kaliappan, Agilan, additional, Kasipandian, Vidya, additional, Kegg, Stephen, additional, Kelsey, Michael, additional, Kendall, Jason, additional, Kerrison, Caroline, additional, Kerslake, Ian, additional, Koch, Oliver, additional, Koduri, Gouri, additional, Koshy, George, additional, Laha, Shondipon, additional, Laird, Steven, additional, Larkin, Susan, additional, Leiner, Tamas, additional, Lillie, Patrick, additional, Limb, James, additional, Linnett, Vanessa, additional, Little, Jeff, additional, Lyttle, Mark, additional, MacMahon, Michael, additional, MacNaughton, Emily, additional, Mankregod, Ravish, additional, Masson, Huw, additional, Matovu, Elijah, additional, McCullough, Katherine, additional, McEwen, Ruth, additional, Meda, Manjula, additional, Mills, Gary, additional, Minton, Jane, additional, Mohandas, Kavya, additional, Mok, Quen, additional, Moon, James, additional, Moore, Elinoor, additional, Morgan, Patrick, additional, Morris, Craig, additional, Mortimore, Katherine, additional, Moses, Samuel, additional, Mpenge, Mbiye, additional, Mulla, Rohinton, additional, Murphy, Michael, additional, Nagarajan, Thapas, additional, Nagel, Megan, additional, Nelson, Mark, additional, Norris, Lillian, additional, O'Shea, Matthew K., additional, Ostermann, Marlies, additional, Otahal, Igor, additional, Pais, Mark, additional, Panchatsharam, Selva, additional, Papakonstantinou, Danai, additional, Papineni, Padmasayee, additional, Paraiso, Hassan, additional, Patel, Brij, additional, Pattison, Natalie, additional, Pepperell, Justin, additional, Peters, Mark, additional, Phull, Mandeep, additional, Pintus, Stefania, additional, Planche, Tim, additional, Post, Frank, additional, Price, David, additional, Prout, Rachel, additional, Rae, Nikolas, additional, Reschreiter, Henrik, additional, Reynolds, Tim, additional, Richardson, Neil, additional, Roberts, Mark, additional, Roberts, Devender, additional, Rose, Alistair, additional, Rousseau, Guy, additional, Ruge, Bobby, additional, Ryan, Brendan, additional, Saluja, Taranprit, additional, Sarah, Sarah, additional, Schmid, Matthias, additional, Shah, Aarti, additional, Shankar-Hari, Manu, additional, Shanmuga, Prad, additional, Sharma, Anil, additional, Shawcross, Anna, additional, Singh Pooni, Jagtur, additional, Sizer, Jeremy, additional, Smith, Richard, additional, Snelson, Catherine, additional, Spittle, Nick, additional, Staines, Nikki, additional, Stambach, Tom, additional, Stewart, Richard, additional, Subudhi, Pradeep, additional, Szakmany, Tamas, additional, Tatham, Kate, additional, Thomas, Jo, additional, Thompson, Chris, additional, Thompson, Robert, additional, Tridente, Ascanio, additional, Tupper-Carey, Darell, additional, Twagira, Mary, additional, Vallotton, Nick, additional, Vancheeswaran, Rama, additional, Vincent, Rachel, additional, Vincent-Smith, Lisa, additional, Visuvanathan, Shico, additional, Vuylsteke, Alan, additional, Waddy, Sam, additional, Wake, Rachel, additional, Walden, Andrew, additional, Welters, Ingeborg, additional, Whitehouse, Tony, additional, Whittaker, Paul, additional, Whittington, Ashley, additional, Wijesinghe, Meme, additional, Williams, Martin, additional, Wilson, Lawrence, additional, Winchester, Stephen, additional, Wiselka, Martin, additional, Wolverson, Adam, additional, Wootton, Daniel G, additional, Workman, Andrew, additional, Yates, Bryan, additional, Young, Peter, additional, McDonald, Sarah E., additional, Shaw, Victoria, additional, Ahmed, Katie A., additional, Armstrong, Jane A., additional, Ashworth, Milton, additional, Asiimwe, Innocent G., additional, Bakshi, Siddharth, additional, Barlow, Samantha L, additional, Booth, Laura, additional, Brennan, Benjamin, additional, Bullock, Katie, additional, Carlucci, Nicola, additional, Cass, Emily, additional, Catterall, Benjamin W.A., additional, Clark, Jordan J., additional, Clarke, Emily A., additional, Cole, Sarah, additional, Cooper, Louise, additional, Cox, Helen, additional, Davis, Christopher, additional, Dincarslan, Oslem, additional, Doce Carracedo, Alejandra, additional, Dunn, Chris, additional, Dyer, Philip, additional, Elliott, Angela, additional, Evans, Anthony, additional, Finch, Lorna, additional, Fisher, Lewis W.S., additional, Flaherty, Lisa, additional, Foster, Terry, additional, Garcia-Dorival, Isabel, additional, Gunning, Philip, additional, Hartley, Catherine, additional, Holmes, Anthony, additional, Jensen, Rebecca L., additional, Jones, Christopher B., additional, Jones, Trevor R., additional, Khandaker, Shadia, additional, King, Katharine, additional, Kiy, Robyn T., additional, Koukorava, Chrysa, additional, Lake, Annette, additional, Lant, Suzannah, additional, Latawiec, Diane, additional, Lavelle-Langham, Lara, additional, Lefteri, Daniella, additional, Lett, Lauren, additional, Livoti, Lucia A, additional, Mancini, Maria, additional, Massey, Hannah, additional, Maziere, Nicole, additional, McDonald, Sarah, additional, McEvoy, Laurence, additional, McLauchlan, John, additional, Metelmann, Soeren, additional, Miah, Nahida S., additional, Middleton, Joanna, additional, Mitchell, Joyce, additional, Murphy, Ellen G, additional, Penrice-Randal, Rebekah, additional, Pilgrim, Jack, additional, Prince, Tessa, additional, Reynolds, Will, additional, Ridley, P. Matthew, additional, Sales, Debby, additional, Shaw, Victoria E., additional, Shears, Rebecca K., additional, Small, Benjamin, additional, Subramaniam, Krishanthi S., additional, Szemiel, Agnieska, additional, Taggart, Aislynn, additional, Tanianis-Hughes, Jolanta, additional, Thomas, Jordan, additional, Trochu, Erwan, additional, van Tonder, Libby, additional, Wilcock, Eve, additional, Zhang, J. Eunice, additional, Keating, Seán, additional, Donegan, Cara, additional, Spencer, Rebecca G., additional, Donohue, Chloe, additional, Griffiths, Fiona, additional, Hardwick, Hayley, additional, Oosthuyzen, Wilna, additional, Abel, K., additional, Adamali, H., additional, Adeloye, D., additional, Adeyemi, O., additional, Adrego, R., additional, Aguilar Jimenez, L.A., additional, Ahmad, S., additional, Ahmad Haider, N., additional, Ahmed, R., additional, Ahwireng, N., additional, Ainsworth, M., additional, Al-Sheklly, B., additional, Alamoudi, A., additional, Ali, M., additional, Aljaroof, M., additional, All, A.M., additional, Allan, L., additional, Allen, R.J., additional, Allerton, L., additional, Allsop, L., additional, Almeida, P., additional, Altmann, D., additional, Alvarez Corral, M., additional, Amoils, S., additional, Anderson, D., additional, Antoniades, C., additional, Arbane, G., additional, Arias, A., additional, Armour, C., additional, Armstrong, L., additional, Armstrong, N., additional, Arnold, D., additional, Arnold, H., additional, Ashish, A., additional, Ashworth, A., additional, Ashworth, M., additional, Aslani, S., additional, Assefa-Kebede, H., additional, Atkin, C., additional, Atkin, P., additional, Aul, R., additional, Aung, H., additional, Austin, L., additional, Avram, C., additional, Ayoub, A., additional, Babores, M., additional, Baggott, R., additional, Bagshaw, J., additional, Baguley, D., additional, Bailey, L., additional, Baillie, J.K., additional, Bain, S., additional, Bakali, M., additional, Bakau, M., additional, Baldry, E., additional, Baldwin, D., additional, Baldwin, M., additional, Ballard, C., additional, Banerjee, A., additional, Bang, B., additional, Barker, R.E., additional, Barman, L., additional, Barratt, S., additional, Barrett, F., additional, Basire, D., additional, Basu, N., additional, Bates, M., additional, Bates, A., additional, Batterham, R., additional, Baxendale, H., additional, Bayes, H., additional, Beadsworth, M., additional, Beckett, P., additional, Beggs, M., additional, Begum, M., additional, Beirne, P., additional, Bell, D., additional, Bell, R., additional, Bennett, K., additional, Beranova, E., additional, Bermperi, A., additional, Berridge, A., additional, Berry, C., additional, Betts, S., additional, Bevan, E., additional, Bhui, K., additional, Bingham, M., additional, Birchall, K., additional, Bishop, L., additional, Bisnauthsing, K., additional, Blaikely, J., additional, Bloss, A., additional, Bolger, A., additional, Bolton, C.E., additional, Bonnington, J., additional, Botkai, A., additional, Bourne, C., additional, Bourne, M., additional, Bramham, K., additional, Brear, L., additional, Breen, G., additional, Breeze, J., additional, Briggs, A., additional, Bright, E., additional, Brightling, C.E., additional, Brill, S., additional, Brindle, K., additional, Broad, L., additional, Broadley, A., additional, Brookes, C., additional, Broome, M., additional, Brown, A., additional, Brown, J., additional, Brown, J.S., additional, Brown, M., additional, Brown, V., additional, Brugha, T., additional, Brunskill, N., additional, Buch, M., additional, Buckley, P., additional, Bularga, A., additional, Bullmore, E., additional, Burden, L., additional, Burdett, T., additional, Burn, D., additional, Burns, G., additional, Burns, A., additional, Busby, J., additional, Butcher, R., additional, Butt, A., additional, Byrne, S., additional, Cairns, P., additional, Calder, P.C., additional, Calvelo, E., additional, Carborn, H., additional, Card, B., additional, Carr, C., additional, Carr, L., additional, Carson, G., additional, Carter, P., additional, Casey, A., additional, Cassar, M., additional, Cavanagh, J., additional, Chablani, M., additional, Chalder, T., additional, Chalmers, J.D., additional, Chambers, R.C., additional, Chan, F., additional, Channon, K.M., additional, Chapman, K., additional, Charalambou, A., additional, Chaudhuri, N., additional, Checkley, A., additional, Chen, J., additional, Cheng, Y., additional, Chetham, L., additional, Childs, C., additional, Chilvers, E.R., additional, Chinoy, H., additional, Chiribiri, A., additional, Chong-James, K., additional, Choudhury, G., additional, Choudhury, N., additional, Chowienczyk, P., additional, Christie, C., additional, Chrystal, M., additional, Clark, D., additional, Clark, C., additional, Clarke, J., additional, Clohisey, S., additional, Coakley, G., additional, Coburn, Z., additional, Coetzee, S., additional, Cole, J., additional, Coleman, C., additional, Conneh, F., additional, Connell, D., additional, Connolly, B., additional, Connor, L., additional, Cook, A., additional, Cooper, B., additional, Cooper, J., additional, Cooper, S., additional, Copeland, D., additional, Cosier, T., additional, Coulding, M., additional, Coupland, C., additional, Cox, E., additional, Craig, T., additional, Crisp, P., additional, Cristiano, D., additional, Crooks, M.G., additional, Cross, A., additional, Cruz, I., additional, Cullinan, P., additional, Cuthbertson, D., additional, Daines, L., additional, Dalton, M., additional, Daly, P., additional, Daniels, A., additional, Dark, P., additional, Dasgin, J., additional, David, A., additional, David, C., additional, Davies, E., additional, Davies, F., additional, Davies, G., additional, Davies, G.A., additional, Davies, K., additional, Davies, M.J., additional, Dawson, J., additional, Daynes, E., additional, De Soyza, A., additional, Deakin, B., additional, Deans, A., additional, Deas, C., additional, Deery, J., additional, Defres, S., additional, Dell, A., additional, Dempsey, K., additional, Denneny, E., additional, Dennis, J., additional, Dewar, A., additional, Dharmagunawardena, R., additional, Diar-Bakerly, N., additional, Dickens, C., additional, Dipper, A., additional, Diver, S., additional, Diwanji, S.N., additional, Dixon, M., additional, Djukanovic, R., additional, Dobson, H., additional, Dobson, S.L., additional, Docherty, A.B., additional, Donaldson, A., additional, Dong, T., additional, Dormand, N., additional, Dougherty, A., additional, Dowling, R., additional, Drain, S., additional, Draxlbauer, K., additional, Drury, K., additional, Dulawan, P., additional, Dunleavy, A., additional, Dunn, S., additional, Dupont, C., additional, Earley, J., additional, Easom, N., additional, Echevarria, C., additional, Edwards, S., additional, Edwardson, C., additional, El-Taweel, H., additional, Elliott, A., additional, Elliott, K., additional, Ellis, Y., additional, Elmer, A., additional, Elneima, O., additional, Evans, D., additional, Evans, H., additional, Evans, J., additional, Evans, R., additional, Evans, R.A., additional, Evans, R.I., additional, Evans, T., additional, Evenden, C., additional, Evison, L., additional, Fabbri, L., additional, Fairbairn, S., additional, Fairman, A., additional, Fallon, K., additional, Faluyi, D., additional, Favager, C., additional, Fayzan, T., additional, Featherstone, J., additional, Felton, T., additional, Finch, J., additional, Finney, S., additional, Finnigan, J., additional, Finnigan, L., additional, Fisher, H., additional, Fletcher, S., additional, Flockton, R., additional, Flynn, M., additional, Foot, H., additional, Foote, D., additional, Ford, A., additional, Forton, D., additional, Fraile, E., additional, Francis, C., additional, Francis, R., additional, Francis, S., additional, Frankel, A., additional, Fraser, E., additional, Free, R., additional, French, N., additional, Fu, X., additional, Fuld, J., additional, Furniss, J., additional, Garner, L., additional, Gautam, N., additional, Geddes, J.R., additional, George, J., additional, George, P., additional, Gibbons, M., additional, Gill, M., additional, Gilmour, L., additional, Gleeson, F., additional, Glossop, J., additional, Glover, S., additional, Goodman, N., additional, Goodwin, C., additional, Gooptu, B., additional, Gordon, H., additional, Gorsuch, T., additional, Greatorex, M., additional, Greenhaff, P.L., additional, Greenhalf, W., additional, Greenhalgh, A., additional, Greening, N.J., additional, Greenwood, J., additional, Gregory, H., additional, Gregory, R., additional, Grieve, D., additional, Griffin, D., additional, Griffiths, L., additional, Guerdette, A-M., additional, Guillen Guio, B., additional, Gummadi, M., additional, Gupta, A., additional, Gurram, S., additional, Guthrie, E., additional, Guy, Z., additional, H Henson, H., additional, Hadley, K., additional, Haggar, A., additional, Hainey, K., additional, Hairsine, B., additional, Haldar, P., additional, Hall, I., additional, Hall, L., additional, Halling-Brown, M., additional, Hamil, R., additional, Hancock, A., additional, Hancock, K., additional, Hanley, N.A., additional, Haq, S., additional, Hardwick, H.E., additional, Hardy, E., additional, Hardy, T., additional, Hargadon, B., additional, Harrington, K., additional, Harris, E., additional, Harris, V.C., additional, Harrison, E.M., additional, Harrison, P., additional, Hart, N., additional, Harvey, A., additional, Harvey, M., additional, Harvie, M., additional, Haslam, L., additional, Havinden-Williams, M., additional, Hawkes, J., additional, Hawkings, N., additional, Haworth, J., additional, Hayday, A., additional, Haynes, M., additional, Hazeldine, J., additional, Hazelton, T., additional, Heaney, L.G., additional, Heeley, C., additional, Heeney, J.L., additional, Heightman, M., additional, Heller, S., additional, Henderson, M., additional, Hesselden, L., additional, Hewitt, M., additional, Highett, V., additional, Hillman, T., additional, Hiwot, T., additional, Ho, L.P., additional, Hoare, A., additional, Hoare, M., additional, Hockridge, J., additional, Hogarth, P., additional, Holbourn, A., additional, Holden, S., additional, Holdsworth, L., additional, Holgate, D., additional, Holland, M., additional, Holloway, L., additional, Holmes, K., additional, Holmes, M., additional, Holroyd-Hind, B., additional, Holt, L., additional, Hormis, A., additional, Horsley, A., additional, Hosseini, A., additional, Hotopf, M., additional, Houchen-Wolloff, L., additional, Howard, K., additional, Howard, L.S., additional, Howell, A., additional, Hufton, E., additional, Hughes, A.D., additional, Hughes, J., additional, Hughes, R., additional, Humphries, A., additional, Huneke, N., additional, Hurditch, E., additional, Hurst, J., additional, Husain, M., additional, Hussell, T., additional, Hutchinson, J., additional, Ibrahim, W., additional, Ilyas, F., additional, Ingham, J., additional, Ingram, L., additional, Ionita, D., additional, Isaacs, K., additional, Ismail, K., additional, Jackson, T., additional, Jacob, J., additional, James, W.Y., additional, Jang, W., additional, Jarman, C., additional, Jarrold, I., additional, Jarvis, H., additional, Jastrub, R., additional, Jayaraman, B., additional, Jenkins, R.G., additional, Jezzard, P., additional, Jiwa, K., additional, Johnson, C., additional, Johnson, S., additional, Johnston, D., additional, Jolley, C.J., additional, Jones, D., additional, Jones, G., additional, Jones, H., additional, Jones, I., additional, Jones, L., additional, Jones, M.G., additional, Jones, S., additional, Jose, S., additional, Kabir, T., additional, Kaltsakas, G., additional, Kamwa, V., additional, Kanellakis, N., additional, Kaprowska, s., additional, Kausar, Z., additional, Keenan, N., additional, Kelly, S., additional, Kemp, G., additional, Kerr, S., additional, Kerslake, H., additional, Key, A.L., additional, Khan, F., additional, Khunti, K., additional, Kilroy, S., additional, King, B., additional, King, C., additional, Kingham, L., additional, Kirk, J., additional, Kitterick, P., additional, Klenerman, P., additional, Knibbs, L., additional, Knight, S., additional, Knighton, A., additional, Kon, O., additional, Kon, S., additional, Kon, S.S., additional, Koprowska, S., additional, Korszun, A., additional, Koychev, I., additional, Kurasz, C., additional, Kurupati, P., additional, Laing, C., additional, Lamlum, H., additional, Landers, G., additional, Langenberg, C., additional, Lasserson, D., additional, Lavelle-Langham, L., additional, Lawrie, A., additional, Lawson, C., additional, Layton, A., additional, Lea, A., additional, Leavy, O.C., additional, Lee, D., additional, Lee, J-H., additional, Lee, E., additional, Leitch, K., additional, Lenagh, R., additional, Lewis, D., additional, Lewis, J., additional, Lewis, K.E., additional, Lewis, V., additional, Lewis-Burke, N., additional, Li, X., additional, Light, T., additional, Lightstone, L., additional, Lilaonitkul, W., additional, Lim, L., additional, Linford, S., additional, Lingford-Hughes, A., additional, Lipman, M., additional, Liyanage, K., additional, Lloyd, A., additional, Logan, S., additional, Lomas, D., additional, Lone, N.I., additional, Loosley, R., additional, Lord, J.M., additional, Lota, H., additional, Lovegrove, W., additional, Lucey, A., additional, Lukaschuk, E., additional, Lye, A., additional, Lynch, C., additional, MacDonald, S., additional, MacGowan, G., additional, Macharia, I., additional, Mackie, J., additional, Macliver, L., additional, Madathil, S., additional, Madzamba, G., additional, Magee, N., additional, Magtoto, M.M., additional, Mairs, N., additional, Majeed, N., additional, Major, E., additional, Malein, F., additional, Malim, M., additional, Mallison, G., additional, Man, W.D.-C., additional, Mandal, S., additional, Mangion, K., additional, Manisty, C., additional, Manley, R., additional, March, K., additional, Marciniak, S., additional, Marino, P., additional, Mariveles, M., additional, Marks, M., additional, Marouzet, E., additional, Marsh, S., additional, Marshall, B., additional, Marshall, M., additional, Martin, J., additional, Martineau, A., additional, Martinez, L.M., additional, Maskell, N., additional, Matila, D., additional, Matimba-Mupaya, W., additional, Matthews, L., additional, Mbuyisa, A., additional, McAdoo, S., additional, McAllister-Williams, H., additional, McArdle, A., additional, McArdle, P., additional, McAulay, D., additional, McCann, G.P., additional, drury, H.J.C., additional, McCormick, J., additional, McCormick, W., additional, McCourt, P., additional, McGarvey, L., additional, McGee, C., additional, Mcgee, K., additional, McGinness, J., additional, McGlynn, K., additional, McGovern, A., additional, McGuinness, H., additional, McInnes, I.B., additional, McIntosh, J., additional, McIvor, E., additional, McIvor, K., additional, McLeavey, L., additional, McMahon, A., additional, McMahon, M.J., additional, McMorrow, L., additional, Mcnally, T., additional, McNarry, M., additional, McNeill, J., additional, McQueen, A., additional, McShane, H., additional, Mears, C., additional, Megson, C., additional, Megson, S., additional, Mehta, P., additional, Meiring, J., additional, Melling, L., additional, Mencias, M., additional, Menzies, D., additional, Merida Morillas, M., additional, Michael, A., additional, Miller, C., additional, Milligan, L., additional, Mills, C., additional, Mills, N.L., additional, Milner, L., additional, Misra, S., additional, Mitchell, J., additional, Mohamed, A., additional, Mohamed, N., additional, Mohammed, S., additional, Molyneaux, P.L., additional, Monteiro, W., additional, Moriera, S., additional, Morley, A., additional, Morrison, L., additional, Morriss, R., additional, Morrow, A., additional, Moss, A.J., additional, Moss, P., additional, Motohashi, K., additional, Msimanga, N., additional, Mukaetova-Ladinska, E., additional, Munawar, U., additional, Murira, J., additional, Nanda, U., additional, Nassa, H., additional, Nasseri, M., additional, Neal, A., additional, Needham, R., additional, Neill, P., additional, Neubauer, S., additional, Newby, D.E., additional, Newell, H., additional, Newman, T., additional, Newton-Cox, A., additional, Nicholson, T., additional, Nicoll, D., additional, Nikolaidis, A., additional, Nolan, C.M., additional, Noonan, M.J., additional, Norman, C., additional, Novotny, P., additional, Nunag, J., additional, Nwafor, L., additional, Nwanguma, U., additional, Nyaboko, J., additional, O'Brien, C., additional, O'Donnell, K., additional, O'Regan, D., additional, O'Brien, L., additional, Odell, N., additional, Ogg, G., additional, Olaosebikan, O., additional, Oliver, C., additional, Omar, Z., additional, Openshaw, P.J.M., additional, Orriss-Dib, L., additional, Osborne, L., additional, Osbourne, R., additional, Ostermann, M., additional, Overton, C., additional, Owen, J., additional, Oxton, J., additional, Pack, J., additional, Pacpaco, E., additional, Paddick, S., additional, Painter, S., additional, Pakzad, A., additional, Palmer, S., additional, Papineni, P., additional, Paques, K., additional, Paradowski, K., additional, Pareek, M., additional, Parekh, D., additional, Parfrey, H., additional, Pariante, C., additional, Parker, S., additional, Parkes, M., additional, Parmar, J., additional, Patale, S., additional, Patel, B., additional, Patel, M., additional, Patel, S., additional, Pattenadk, D., additional, Pavlides, M., additional, Payne, S., additional, Pearce, L., additional, Pearl, J.E., additional, Peckham, D., additional, Pendlebury, J., additional, Peng, Y., additional, Pennington, C., additional, Peralta, I., additional, Perkins, E., additional, Peterkin, Z., additional, Peto, T., additional, Petousi, N., additional, Petrie, J., additional, Pfeffer, P., additional, Phipps, J., additional, Pimm, J., additional, Piper Hanley, K., additional, Pius, R., additional, Plant, H., additional, Plein, S., additional, Plekhanova, T., additional, Plowright, M., additional, Poinasamy, K., additional, Polgar, O., additional, Poll, L., additional, Porter, J.C., additional, Porter, J., additional, Portukhay, S., additional, Powell, N., additional, Prabhu, A., additional, Pratt, J., additional, Price, A., additional, Price, C., additional, Price, D., additional, Price, L., additional, Prickett, A., additional, Propescu, J., additional, Prosper, S., additional, Pugmire, S., additional, Quaid, S., additional, Quigley, J., additional, Quint, J., additional, Qureshi, H., additional, Qureshi, I.N., additional, Radhakrishnan, K., additional, Rahman, N.M., additional, Ralser, M., additional, Raman, B., additional, Ramos, A., additional, Ramos, H., additional, Rangeley, J., additional, Rangelov, B., additional, Ratcliffe, L., additional, Ravencroft, P., additional, Reddington, A., additional, Reddy, R., additional, Redfearn, H., additional, Redwood, D., additional, Reed, A., additional, Rees, M., additional, Rees, T., additional, Regan, K., additional, Reynolds, W., additional, Ribeiro, C., additional, Richards, A., additional, Richardson, E., additional, Richardson, M., additional, Rivera-Ortega, P., additional, Roberts, K., additional, Robertson, E., additional, Robinson, E., additional, Robinson, L., additional, Roche, L., additional, Roddis, C., additional, Rodger, J., additional, Ross, A., additional, Ross, G., additional, Rossdale, J., additional, Rostron, A., additional, Rowe, A., additional, Rowland, A., additional, Rowland, J., additional, Rowland, M.J., additional, Rowland-Jones, S.L., additional, Roy, K., additional, Roy, M., additional, Rudan, I., additional, Russell, R., additional, Russell, E., additional, Saalmink, G., additional, Sabit, R., additional, Sage, E.K., additional, Samakomva, T., additional, Samani, N., additional, Sampson, C., additional, Samuel, K., additional, Samuel, R., additional, Sanderson, A., additional, Sapey, E., additional, Saralaya, D., additional, Sargant, J., additional, Sarginson, C., additional, Sass, T., additional, Sattar, N., additional, Saunders, K., additional, Saunders, R.M., additional, Saunders, P., additional, Saunders, L.C., additional, Savill, H., additional, Saxon, W., additional, Sayer, A., additional, Schronce, J., additional, Schwaeble, W., additional, Scott, J.T., additional, Scott, K., additional, Selby, N., additional, Semple, M.G., additional, Sereno, M., additional, Sewell, T.A., additional, Shah, A., additional, Shah, K., additional, Shah, P., additional, Shankar-Hari, M., additional, Sharma, M., additional, Sharpe, C., additional, Sharpe, M., additional, Shashaa, S., additional, Shaw, A., additional, Shaw, K., additional, Shaw, V., additional, Sheikh, A., additional, Shelton, S., additional, Shenton, L., additional, Shevket, K., additional, Shikotra, A., additional, Short, J., additional, Siddique, S., additional, Siddiqui, S., additional, Sidebottom, J., additional, Sigfrid, L., additional, Simons, G., additional, Simpson, J., additional, Simpson, N., additional, Singapuri, A., additional, Singh, C., additional, Singh, S., additional, Singh, S.J., additional, Sissons, D., additional, Skeemer, J., additional, Slack, K., additional, Smith, A., additional, Smith, D., additional, Smith, S., additional, Smith, J., additional, Smith, L., additional, Soares, M., additional, Solano, T.S., additional, Solly, R., additional, Solstice, A.R., additional, Soulsby, T., additional, Southern, D., additional, Sowter, D., additional, Spears, M., additional, Spencer, L.G., additional, Speranza, F., additional, Stadon, L., additional, Stanel, S., additional, Steele, N., additional, Steiner, M., additional, Stensel, D., additional, Stephens, G., additional, Stephenson, L., additional, Stern, M., additional, Stewart, I., additional, Stimpson, R., additional, Stockdale, S., additional, Stockley, J., additional, Stoker, W., additional, Stone, R., additional, Storrar, W., additional, Storrie, A., additional, Storton, K., additional, Stringer, E., additional, Strong-Sheldrake, S., additional, Stroud, N., additional, Subbe, C., additional, Sudlow, C.L., additional, Suleiman, Z., additional, Summers, C., additional, Summersgill, C., additional, Sutherland, D., additional, Sykes, D.L., additional, Sykes, R., additional, Talbot, N., additional, Tan, A.L., additional, Tarusan, L., additional, Tavoukjian, V., additional, Taylor, A., additional, Taylor, C., additional, Taylor, J., additional, Te, A., additional, Tedd, H., additional, Tee, C.J., additional, Teixeira, J., additional, Tench, H., additional, Terry, S., additional, Thackray-Nocera, S., additional, Thaivalappil, F., additional, Thamu, B., additional, Thickett, D., additional, Thomas, C., additional, Thomas, D.C., additional, Thomas, S., additional, Thomas, A.K., additional, Thomas-Woods, T., additional, Thompson, T., additional, Thompson, A.A.R., additional, Thornton, T., additional, Thorpe, M., additional, Thwaites, R.S., additional, Tilley, J., additional, Tinker, N., additional, Tiongson, G.F., additional, Tobin, M., additional, Tomlinson, J., additional, Tong, C., additional, Toshner, M., additional, Touyz, R., additional, Tripp, K.A., additional, Tunnicliffe, E., additional, Turnbull, A., additional, Turner, E., additional, Turner, S., additional, Turner, V., additional, Turner, K., additional, Turney, S., additional, Turtle, L., additional, Turton, H., additional, Ugoji, J., additional, Ugwuoke, R., additional, Upthegrove, R., additional, Valabhji, J., additional, Ventura, M., additional, Vere, J., additional, Vickers, C., additional, Vinson, B., additional, Wade, E., additional, Wade, P., additional, Wain, L.V., additional, Wainwright, T., additional, Wajero, L.O., additional, Walder, S., additional, Walker, S., additional, Wall, E., additional, Wallis, T., additional, Walmsley, S., additional, Walsh, J.A., additional, Walsh, S., additional, Warburton, L., additional, Ward, T.J.C., additional, Warwick, K., additional, Wassall, H., additional, Waterson, S., additional, Watson, E., additional, Watson, L., additional, Watson, J., additional, Weir McCall, J., additional, Welch, C., additional, Welch, H., additional, Welsh, B., additional, Wessely, S., additional, West, S., additional, Weston, H., additional, Wheeler, H., additional, White, S., additional, Whitehead, V., additional, Whitney, J., additional, Whittaker, S., additional, Whittam, B., additional, Whitworth, V., additional, Wight, A., additional, Wild, J., additional, Wilkins, M., additional, Wilkinson, D., additional, Williams, B., additional, Williams, N., additional, Williams, J., additional, Williams-Howard, S.A., additional, Willicombe, M., additional, Willis, G., additional, Willoughby, J., additional, Wilson, A., additional, Wilson, D., additional, Wilson, I., additional, Window, N., additional, Witham, M., additional, Wolf-Roberts, R., additional, Wood, C., additional, Woodhead, F., additional, Woods, J., additional, Wootton, D.G., additional, Wormleighton, J., additional, Worsley, J., additional, Wraith, D., additional, Wrey Brown, C., additional, Wright, C., additional, Wright, L., additional, Wright, S., additional, Wyles, J., additional, Wynter, I., additional, Xu, M., additional, Yasmin, N., additional, Yasmin, S., additional, Yates, T., additional, Yip, K.P., additional, Young, B., additional, Young, S., additional, Young, A., additional, Yousuf, A.J., additional, Zawia, A., additional, Zeidan, L., additional, Zhao, B., additional, Zheng, B., additional, and Zongo, O., additional
Published: 2023
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8. Resistance exercise and the mechanisms of muscle mass regulation in humans: Acute effects on muscle protein turnover and the gaps in our understanding of chronic resistance exercise training adaptation

Author: Murton, A.J. and Greenhaff, P.L.
Published: 2013
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9. The involvement of the ubiquitin proteasome system in human skeletal muscle remodelling and atrophy

Author: Murton, A.J., Constantin, D., and Greenhaff, P.L.
Published: 2008
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10. Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle

Author: Greenhaff, P.L., Karagounis, L.G., Peirce, N., Simpson, E.J., Hazell, M., Layfield, R., Wackerhage, H., Smith, K., Atherton, P., Selby, A., and Rennie, M.J.
Subjects: Protein biosynthesis -- Influence, Muscle proteins -- Properties, Amino acids -- Properties, Ubiquitin-proteasome system -- Properties, Cellular signal transduction -- Evaluation, Biological sciences
Abstract: We determined the effects of intravenous infusion of amino acids (AA) at serum insulin of 5, 30, 72, and 167 mU/l on anabolic signaling, expression of ubiquitin-proteasome components, and protein turnover in muscles of healthy young men. Tripling AA availability at 5 mU/l insulin doubled incorporation of [1-[sup.13]C]leucine [i.e., muscle protein synthesis (MPS), P < 0.01] without affecting the rate of leg protein breakdown (LPB; appearance of [d.sub.5]-phenylalanine). While keeping AA availability constant, increasing insulin to 30 mU/l halved LPB (P < 0.05) without further inhibition at higher doses, whereas rates of MPS were identical to that at 5 mU/l insulin. The phosphorylation of PKB [Ser.sup.473] and [p70.sup.s6k] [Thr.sup.389] increased concomitantly with insulin, but whereas raising insulin to 30 mU/l increased the phosphorylation of mTOR [Ser.sup.2448], 4E-BP1 [Thr.sup.37/46], or GSK3[beta] [Ser.sup.9] and decreased that of eEF2 [Thr.sup.56], higher insulin doses to 72 and 167 mU/l did not augment these latter responses. MAFbx and proteasome C2 subunit proteins declined as insulin increased, with MuRF-1 expression largely unchanged. Thus increasing AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway, which cannot be easily reconciled with observed effects on MPS or LPB. muscle protein synthesis; muscle protein breakdown
Published: 2008

11. Impaired insulin sensitivity and carbohydrate oxidation during bed rest in healthy participants

Author: Shur, N., primary, Simpson, E.J., additional, Chivaka, P., additional, Crossland, H., additional, Constantin, D., additional, Constantin-Teodosiu, T., additional, Stephens, F.B., additional, Lobo, D.N., additional, Prats, C., additional, MacDonald, I.A., additional, and Greenhaff, P.L., additional
Published: 2020
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12. Antecubital vein cannula position impacts on forearm glucose uptake during an oral glucose challenge in healthy volunteers

Author: Bétry, C., primary, Nixon, A.V., additional, Greenhaff, P.L., additional, and Simpson, E.J., additional
Published: 2020
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13. Declines in muscle protein synthesis are a primary metabolic feature of post-operative catabolism: A systematic review and meta-analysis

Author: Jaconelli, M., primary, Lord, J.M., additional, Greenhaff, P.L., additional, Atherton, P.J., additional, Lobo, D.N., additional, and Brook, M.S., additional
Published: 2020
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14. Carbohydrate Metabolism

Author: Greenhaff, P.L., primary, Hultman, E., additional, and Harris, R.C., additional
Published: 2003
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15. Stimulatory effect of insulin on creatine accumulation in human skeletal muscle

Author: Steenge, G.R., Lambourne, J., Casey, A., MacDonald, I.A., and Greenhaff, P.L.
Subjects: Insulin -- Research, Muscles -- Research, Phosphocreatine -- Research, Biological sciences
Abstract: Research was conducted to examine the stimulatory effect of insulin on creatine accumulation in human skeletal muscle. The objectives were to determine whether insulin could stimulate in vivo creatine accumulation in human skeletal muscle, to determine at what plasma insulin concentration a response was evident and to examine whether an insulin-mediated increase in muscle blood blow was associated with any increase in muscle creatine accumulation. Results indicate that plasma creatine concentration was lower at several time points after the administration of insulin.
Published: 1998

16. Physiological responses to cold stress during prolonged intermittent low- and high-intensity walking

Author: Weller, A.S., Millard, C.E., Stroud, M.A., Greenhaff, P.L., and MacDonald, I.A.
Subjects: Exercise -- Physiological aspects, Body temperature -- Regulation, Epinephrine -- Physiological aspects, Biological sciences
Abstract: The effects of cold, wet or windy environment on the physiological responses to prolonged intermittent walking were analyzed in male subjects to characterize cold-induced physiological responses to physical activity. Intermittent low-intensity exercise in a cold, wet and windy environment increased the blood lactate levels and sympathoadrenal activity of male subjects compared to exercise under thermoneutral conditions. Furthermore, cold-induced differences to low-intensity exercise were deleterious to overall exercise performance.
Published: 1997

17. Physiological responses to cold, wet, and windy environment during prolonged intermittent walking

Author: Weller, A.S., Millard, C.E., Stroud, M.A., Greenhaff, P.L., and MacDonald, I.A.
Subjects: Body temperature -- Regulation, Exercise -- Physiological aspects, Epinephrine -- Physiological aspects, Noradrenaline -- Physiological aspects, Biological sciences
Abstract: The effects of prolonged exercise and cold exposure on thermoregulation and metabolism were analyzed in human male volunteers during intermittent walking. Prolonged and high-intensity walking exercise in a cold and neutral environments produced similar alterations in heart rate and rectal temperature. However, high intensity walking exercise in cold environments produced significant increase in plasma epinephrine, blood lactate and glucose levels compared to high intensity exercise in neutral environment.
Published: 1997

18. Dietary supplements for football

Author: Hespel, P., Maughan, R.J., and Greenhaff, P.L.
Subjects: Soccer players -- Food and nutrition, Soccer players -- Physiological aspects, Dietary supplements -- Health aspects, Dietary supplements -- Research
Published: 2006

19. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans

Author: Green, A.L., Hultman, E., Macdonald, I.A., Sewell, D.A., and Greenhaff, P.L.
Subjects: Phosphocreatine -- Physiological aspects, Carbohydrates -- Physiological aspects, Biological sciences
Abstract: The role of carbohydrate (CHO) in the regulation of skeletal muscle creatine (Cr) uptake was investigated in 24 healthy male subjects. Muscle biopsy, blood, and urine samples were analyzed following ingestion of Cr or CHO. Subjects who ingested CHO showed a greater increase in muscle Cr, Cr, and total Cr than subjects who ingested Cr. They also showed a decrease in Cr excretion, suggesting that CHO augments skeletal muscle Cr accumulation.
Published: 1996

20. Creatine ingestion favorably affects performance and muscle metabolism during maximal exercise in humans

Author: Casey, A., Constantin-Teodosiu, D., Howell, S., Hultman, E., and Greenhaff, P.L.
Subjects: Phosphocreatine -- Physiological aspects, Exercise -- Physiological aspects, Muscles -- Physiological aspects, Biological sciences
Abstract: Dietary creatine (Cr) supplementation enhances exercise performance in humans. To test this hypothesis, nine healthy male subjects were examined. The subjects showed increases in muscle total Cr concentration during exercise following ingestion of Cr. The increases were associated with an increase in the resynthesis of adenosine triphosphate (ATP) that were caused by the increase in availability of phosphocreatine in type II muscle fibers.
Published: 1996

21. Metabolic response of type I and II muscle fibers during repeated bouts of maximal exercise in humans

Author: Casey, A., Constantin-Teodosiu, D., Howell, S., Hultman, E., and Greenhaff, P.L.
Subjects: Exercise -- Physiological aspects, Phosphocreatine -- Physiological aspects, Fatigue -- Physiological aspects, Muscles -- Physiological aspects, Biological sciences
Abstract: Fatigue develops as a result of the loss of adenosine triphosphate (ATP) in type II muscle fibers as a consequence of the rapid loss of phosphocreatine (PCR) stores in this fiber type. These PCR stores increase during recovery after maximal exercise due to an increase in PCR resynthesis. PCR resynthesis produces an increase in total work production and increases ATP and PCR in type II muscle fibers.
Published: 1996

22. Metabolic responses of canine gracilis muscle during contraction with partial ischemia

Author: Timmons, J.A., Poucher, S.M., Constantin-Teodosiu, D., Worrall, V., Macdonald, I.A., and Greenhaff, P.L.
Subjects: Ischemia -- Physiological aspects, Muscles -- Physiological aspects, Peripheral vascular diseases -- Physiological aspects, Biological sciences
Abstract: The effects of partial ischemia on skeletal muscle metabolism were investigated by examining the metabolic responses of canine gracilis muscle, which has a relatively high aerobic capacity. Muscles showed a 40% reduction in contractility due to reduced blood flow, increased lactate content and higher phosphocreatine hydrolysis. Acetylcarnitine levels also increased and this increase was correlated to the degree of skeletal muscle fatigue. There were no changes in pyruvate dehydrogenase transformation to its active form during ischemia.
Published: 1996

23. Adenine nucleotide loss in the skeletal muscles during exercise in chronic obstructive pulmonary disease

Author: Steiner, M.C., Evans, R., Deacon, S.J., Singh, S.J., Patel, P., Fox, J., Greenhaff, P.L., and Morgan, M.D.L.
Subjects: Lung diseases, Obstructive -- Physiological aspects, Lung diseases, Obstructive -- Risk factors, Adenylic acid -- Analysis, Oxidative stress -- Physiological aspects, Exercise -- Physiological aspects, Exercise -- Research, Health
Published: 2005

24. Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis

Author: Greenhaff, P.L., Bodin, K., Soderlund, K., and Hultman, E.
Subjects: Creatinine -- Research, Muscle contraction -- Physiological aspects, Biological sciences
Abstract: Dietary creatine ingestion, following intense electrically-induced isometric contraction, raises muscle total creatine concentration and potentiates the phosphocreatine resynthesis for regulation of skeletal muscle energy metabolism. Individuals having a concentration of 120 mmol/kg dry matter before oral intake of creatine, exhibit an accelerated rate of PCr synthesis in the second minute of recovery from intense muscular spasm which reduces the PCr stores.
Published: 1994

25. BJSM reviews: A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance part 4

Author: Burke, L.M., Castell, L.M., Stear, S.J., Rogers, P.J., Blomstrand, E., Gurr, S., Mitchell, N., Stephens, F.B., and Greenhaff, P.L.
Subjects: Athletes -- Food and nutrition, Dietary supplements -- Health aspects, Ergogenic aids -- Health aspects, Antioxidants -- Health aspects, Aspartame -- Nutritional aspects, Branched chain amino acids -- Nutritional aspects, Boron (Nutrient) -- Nutritional aspects, Carnitine -- Nutritional aspects, Health, Sports and fitness
Published: 2009

26. Effect of Oral Creatine Supplementation on Human Muscle GLUT4 Protein Content After Immobilization

Author: Eijnde, B. Op't, Urso, B., Richter, E.A., Greenhaff, P.L., and Hespel, P.
Subjects: Diabetes -- Research, Dietary supplements -- Health aspects -- Research, Creatine -- Health aspects -- Research, Health, Research, Health aspects
Abstract: The purpose of this study was to investigate the effect of oral creatine supplementation on muscle GLUT4 protein content and total creatine and glycogen content during muscle disuse and subsequent [...]
Published: 2001

27. PP030-SUN: The Impact of a Pharmacological Mediated Increase in Muscle Carbohydrate use on Postoperative Insulin Resistance Compared with Oral Carbohydrate Ingestion in Surgical Patients

Author: Varadhan, K.K., primary, Constantin-Teodosiu, D., additional, Constantin, D., additional, Lobo, D.N., additional, and Greenhaff, P.L., additional
Published: 2014
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28. The effect of creatine and resistance training on plasma homocysteine concentration in healthy volunteers

Author: Steenge, G.R., Verhoef, P., and Greenhaff, P.L.
Subjects: Humane Voeding & Gezondheid, Life Science, VLAG, Human Nutrition & Health
Published: 2001

29. American College of Sports Medicine roundtable. The physiological and health effects of oral creatine supplementation

Author: Terjung, R.L., Clarkson, P., Eichner, E.R., Greenhaff, P.L., Hespel, P.J., Israel, R.G., Kraemer, W.J., Meyer, R.A., Spriet, L.L., Tarnopolsky, M.A., Wagenmakers, A.J.M., Williams, M.H., Humane Biologie, and RS: NUTRIM School of Nutrition and Translational Research in Metabolism
Abstract: Creatine (Cr) supplementation has become a common practice among professional, elite, collegiate, amateur, and recreational athletes with the expectation of enhancing exercise performance. Research indicates that Cr supplementation can increase muscle phosphocreatine (PCr) content, but not in all individuals. A high dose of 20 g x d(-1) that is common to many research studies is not necessary, as 3 g x d(-1) will achieve the same increase in PCr given time. Coincident ingestion of carbohydrate with Cr may increase muscle uptake; however, the procedure requires a large amount of carbohydrate. Exercise performance involving short periods of extremely powerful activity can be enhanced, especially during repeated bouts of activity. This is in keeping with the theoretical importance of an elevated PCr content in skeletal muscle. Cr supplementation does not increase maximal isometric strength, the rate of maximal force production, nor aerobic exercise performance. Most of the evidence has been obtained from healthy young adult male subjects with mixed athletic ability and training status. Less research information is available related to the alterations due to age and gender. Cr supplementation leads to weight gain within the first few days, likely due to water retention related to Cr uptake in the muscle. Cr supplementation is associated with an enhanced accrual of strength in strength-training programs, a response not independent from the initial weight gain, but may be related to a greater volume and intensity of training that can be achieved. There is no definitive evidence that Cr supplementation causes gastrointestinal, renal, and/or muscle cramping complications. The potential acute effects of high-dose Cr supplementation on body fluid balance has not been fully investigated, and ingestion of Cr before or during exercise is not recommended. There is evidence that medical use of Cr supplementation is warranted in certain patients (e.g.. neuromuscular disease); future research may establish its potential usefulness in other medical applications. Although Cr supplementation exhibits small but significant physiological and performance changes, the increases in performance are realized during very specific exercise conditions. This suggests that the apparent high expectations for performance enhancement, evident by the extensive use of Cr supplementation, are inordinate.
Published: 2000

30. Energy expenditure using isotope-labelled water (2H2 18O), exercise performance, skeletal muscle enzyme activities and plasma biochemical parameters in humans during 95 days of endurance exercise with inadequate energy intake

Author: Stroud, M.A., Ritz, Patrick, Coward, W.A., Sawyer, M.B., Constantin-Teodosiu, D., Greenhaff, P.L., Macdonald, Ian, Unité de recherche Maladies Métaboliques et Micronutriments (U3M), Institut National de la Recherche Agronomique (INRA), and ProdInra, Migration
Subjects: [SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio]
Published: 1997

31. Inhibition of adipose tissue lipolysis increases intramuscular lipid and glycogen use in vivo in humans

Author: van Loon, L.J., van Loon, L.J., Thomason-Hughes, M., Constantin-Teodosiu, D., Koopman, R., Greenhaff, P.L., Hardie, D.G., Keizer, H.A., Saris, W.H., Wagenmakers, A.J.M., van Loon, L.J., van Loon, L.J., Thomason-Hughes, M., Constantin-Teodosiu, D., Koopman, R., Greenhaff, P.L., Hardie, D.G., Keizer, H.A., Saris, W.H., and Wagenmakers, A.J.M.
Abstract: This study investigates the consequences of inhibition of adipose tissue lipolysis on skeletal muscle substrate use. Ten subjects were studied at rest and during exercise and subsequent recovery under normal, fasting conditions (control trial, CON) and following administration of a nicotinic acid analog (low plasma free fatty acid trial, LFA). Continuous [U-13C]palmitate and [6,6-2H2]glucose infusions were applied to quantify plasma free fatty acid (FFA) and glucose oxidation rates and to estimate intramuscular triacylglycerol (IMTG) and glycogen use. Muscle biopsies were collected to measure 1) fiber type-specific IMTG content; 2) allosteric regulators of hormone-sensitive lipase (HSL), glycogen phosphorylase, and pyruvate dehydrogenase; and 3) the phosphorylation status of HSL at Ser563 and Ser565. Administration of a nicotinic acid analog (acipimox) substantially reduced plasma FFA rate of appearance and subsequent plasma FFA concentrations (P < 0.0001). At rest, this substantially reduced plasma FFA oxidation rates, which was compensated by an increase in the estimated IMTG use (P < 0.05). During exercise, the progressive increase in FFA rate of appearance, uptake, and oxidation was prevented in the LFA trial and matched by greater IMTG and glycogen use. Differential phosphorylation of HSL or relief of its allosteric inhibition by long-chain fatty acyl-CoA could not explain the increase in muscle TG use, but there was evidence to support the contention that regulation may reside at the level of the glucose-fatty acid cycle. This study confirms the hypothesis that plasma FFA availability regulates both intramuscular lipid and glycogen use in vivo in humans.
Published: 2005

32. Increased uncoupling protein 3 content does not affect mitochondrial function in human skeletal muscle in vivo

Author: Hesselink, M.K.C., Hesselink, M.K.C., Greenhaff, P.L., Constantin-Teodosu, D., Hultman, E., Saris, W.H.M., Nieuwlaat, R., Schaart, G., Kornips, C.F.P., Schrauwen, P., Hesselink, M.K.C., Hesselink, M.K.C., Greenhaff, P.L., Constantin-Teodosu, D., Hultman, E., Saris, W.H.M., Nieuwlaat, R., Schaart, G., Kornips, C.F.P., and Schrauwen, P.
Abstract: Increased uncoupling protein 3 content does not affect mitochondrial function in human skeletal muscle in vivo. Hesselink MK, Greenhaff PL, Constantin-Teodosiu D, Hultman E, Saris WH, Nieuwlaat R, Schaart G, Kornips E, Schrauwen P. Department of Movement Sciences, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. matthijs.hesselink@bw.unimaas.nl Phosphocreatine (PCr) resynthesis rate following intense anoxic contraction can be used as a sensitive index of in vivo mitochondrial function. We examined the effect of a diet-induced increase in uncoupling protein 3 (UCP3) expression on postexercise PCr resynthesis in skeletal muscle. Nine healthy male volunteers undertook 20 one-legged maximal voluntary contractions with limb blood flow occluded to deplete muscle PCr stores. Exercise was performed following 7 days consumption of low-fat (LF) or high-fat (HF) diets. Immediately following exercise, blood flow was reinstated, and muscle was sampled after 20, 60, and 120 seconds of recovery. Mitochondrial coupling was assessed by determining the rate of PCr resynthesis during recovery. The HF diet increased UCP3 protein content by approximately 44% compared with the LF diet. However, this HF diet-induced increase in UCP3 expression was not associated with any changes in the rate of muscle PCr resynthesis during conditions of maximal flux through oxidative phosphorylation. Muscle acetylcarnitine, free-creatine, and lactate concentrations during recovery were unaffected by the HF diet. Taken together, our findings demonstrate that increasing muscle UCP3 expression does not diminish the rate of PCr resynthesis, allowing us to conclude that the primary role of UCP3 in humans is not uncoupling.
Published: 2003

33. The effects of increasing exercise intensity on muscle fuel utilisation in humans.

Author: van Loon, L.J.C., van Loon, L.J.C., Greenhaff, P.L., Constantin-Teodosiu, D., Saris, W.H.M., Wagenmakers, A.J.M., van Loon, L.J.C., van Loon, L.J.C., Greenhaff, P.L., Constantin-Teodosiu, D., Saris, W.H.M., and Wagenmakers, A.J.M.
Abstract: J Physiol 2001 Oct 1;536(Pt 1):295-304 Related Articles, Books, LinkOut The effects of increasing exercise intensity on muscle fuel utilisation in humans. van Loon LJ, Greenhaff PL, Constantin-Teodosiu D, Saris WH, Wagenmakers AJ. Nutrition and Toxicology Research Institute NUTRIM, Department of Human Biology, Maastricht University, Maastricht, The Netherlands. l.vanloon@hb.unimaas.nl 1. Contemporary stable isotope methodology was applied in combination with muscle biopsy sampling to accurately quantify substrate utilisation and study the regulation of muscle fuel selection during exercise. 2. Eight cyclists were studied at rest and during three consecutive 30 min stages of exercise at intensities of 40, 55 and 75 % maximal workload (W(max)). A continuous infusion of [U-(13)C]palmitate and [6,6-(2)H(2)]glucose was administered to determine plasma free fatty acid (FFA) oxidation and estimate plasma glucose oxidation, respectively. Biopsy samples were collected before and after each exercise stage. 3. Muscle glycogen and plasma glucose oxidation rates increased with every increment in exercise intensity. Whole-body fat oxidation increased to 32 +/- 2 kJ min(-1) at 55 % W(max), but declined at 75 % W(max) (19 +/- 2 kJ min(-1)). This decline involved a decrease in the oxidation rate of both plasma FFA and triacylglycerol fat sources (sum of intramuscular plus lipoprotein-derived triacylglycerol), and was accompanied by increases in muscle pyruvate dehydrogenase complex activation and acetylation of the carnitine pool, resulting in a decline in muscle free carnitine concentration. 4. We conclude that the most likely mechanism for the reduction in fat oxidation during high-intensity exercise is a downregulation of carnitine palmitoyltransferase I, either by this marked decline in free carnitine availability or by a decrease in intracellular pH.
Published: 2001

34. The acetyl-group deficit limits mitochondrial ATP production at the onset of exercise

Author: Greenhaff, P.L., primary, Campbell, S., additional, Constantin-Teodosiu, D., additional, Poucher, S.M., additional, Roberts, P.A., additional, and Timmons, J.A., additional
Published: 2002
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35. Optimization of insulin-mediated creatine retention during creatine feeding in humans.

Author: Pittas, G., Hazell, M.D., Simpson, E.J., and Greenhaff, P.L.
Subjects: CREATINE, INSULIN research, AMINO acids, SUGARS, PHENYLALANINE, CARBOHYDRATES
Abstract: The aim of this study was to determine whether creatine ingested in combination with relatively small quantities of essential amino acids, simple sugars, and protein would stimulate insulin release and augment whole-body creatine retention to the same extent as a large bolus of simple sugars. Seven young, healthy males underwent three randomized, 3-day experimental trials. Each day, 24-h urine collections were made, and on the second day participants received 5 g creatine + water (creatine trial), 5 g creatine + ∼95 g dextrose (creatine + carbohydrate) or 5 g creatine + 14 g protein hydrolysate, 7 g leucine, 7 g phenylalanine, and 57 g dextrose (creatine + protein, amino acids, and carbohydrate) via naso-gastric tube at three equally spaced intervals. Blood samples were collected at predetermined intervals after the first and third naso-gastric bolus. After administration of the first and third bolus, serum insulin concentration was increased by 15 min (P < 0.05) in the creatine + carbohydrate and creatine + protein, amino acids, and carbohydrate trials compared with creatine alone, and plasma creatine increased more following creatine alone (15 min, P < 0.05) than in the creatine + carbohydrate and creatine + protein, amino acids, and carbohydrate trials. Urinary creatine excretion was greater with creatine alone (P < 0.05) than with creatine + carbohydrate and creatine + protein, amino acids, and carbohydrate. Administration of creatine + protein, amino acids, and carbohydrate can stimulate insulin release and augment whole-body creatine retention to the same extent as when larger quantities of simple sugars are ingested. [ABSTRACT FROM AUTHOR]
Published: 2010
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36. Metabolic inertia in contracting skeletal muscle: a novel approach for pharmacological intervention in peripheral vascular disease.

Author: Greenhaff, P.L., Campbell-O'Sullivan, S.P., Constantin-Teodosiu, D., Poucher, S.M., Roberts, P.A., and Timmons, J.A.
Subjects: *PYRUVATES, *DEHYDROGENASES, *PERIPHERAL vascular disease treatment, *METABOLITES, *METABOLISM, *CLINICAL pharmacology
Abstract: Peripheral vascular disease (PVD) is generally accepted to result in the failure of skeletal muscle blood flow to increase adequately at the onset of muscular work. There are currently no routine pharmacological interventions towards the treatment of PVD, however, recent Phase III trials in the USA have demonstrated the clinical potential of the phosphodiesterase III inhibitor Cilostazol for pain-free and maximal walking distances in patients with intermittent claudication. PVD is characterized by a marked reliance on oxygen-independent routes of ATP regeneration (phosphocreatine hydrolysis and glycolysis) in skeletal muscle during contraction and the rapid onset of muscular pain and fatigue. The accumulation of metabolic by-products of oxygen-independent ATP production (hydrogen and lactate ions and inorganic phosphate) has long been associated with an inhibition in contractile function in both healthy volunteers and PVD patients. Therefore, any strategy that could reduce the reliance upon ATP re-synthesis from oxygen-independent routes, and increase the contribution of oxygen-dependent (mitochondrial) ATP re-synthesis, particularly at the onset of exercise, might be expected to improve functional capacity and be of considerable therapeutic value. Historically, the increased contribution of oxygen-independent ATP re-synthesis to total ATP generation at the onset of exercise has been attributed to a lag in muscle blood flow limiting oxygen delivery during this period. However, recent evidence suggests that limited inertia is present at the level of oxygen delivery, whilst considerable inertia exists at the level of mitochondrial enzyme activation and substrate supply. In support of this latter hypothesis, we have reported on a number of occasions that activation of the pyruvate dehydrogenase complex, using pharmacological interventions, can markedly reduce the dependence on ATP re-synthesis from oxygen-independent routes at the onset of muscle contraction. This review will focus on these findings and will highlight the pyruvate dehydrogenase complex as a novel therapeutic target towards the treatment of peripheral vascular disease, or any other disease state where premature muscular fatigue is prevalent due to metabolite accumulation. [ABSTRACT FROM AUTHOR]
Published: 2004
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37. Carbohydrate Metabolism.

Author: Greenhaff, P.L., Hultman, E., and Harris, R.C.
Published: 2004
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38. Dietary creatine supplementation does not affect some haematological indices, or indices of muscle damage and hepatic and renal function

Author: Robinson, T.M., Sewell, D.A., Casey, A., Steenge, G., and Greenhaff, P.L.
Abstract: BackgroundThe use of creatine (Cr) as a nutritional supplement to aid athletic performance has gained widespread popularity among athletes. However, concerns have recently been expressed over potentially harmful effects of short and long term Cr supplementation on health.MethodsForty eight young healthy subjects were randomly allocated to three experimental protocols aimed at elucidating any potential health risks associated with five days (20 g/day) to nine weeks (3 g/day) of Cr supplementation. Venous blood samples were collected before and after periods of Cr supplementation and were analysed for some haematological indices, and for indices of hepatic, muscular, and renal dysfunction.FindingsAll measured indices were well within their respective normal range at all times. Serum creatinine concentration tended to be increased the day after Cr supplementation. However, values had returned to baseline six weeks after the cessation of supplementation. These increases were probably attributable to increased creatinine production rather than renal dysfunction. No indication of impairment to the haematological indices measured, hepatic function, or muscle damage was apparent after Cr supplementation.InterpretationThese data provide evidence that there are no obvious adverse effects of acute or more chronic Cr supplementation on the haematological indices measured, nor on hepatic, muscle, and renal function. Therefore there is no apparent health risk associated with Cr supplementation to healthy people when it is ingested in quantities that have been scientifically proven to increase muscle Cr stores.
Published: 2000

39. Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol

Author: Gladman, J.R.F., Greenhaff, P.L., Aloraibi, S., Phillips, B., Atherton, P., Masud, T., Sahota, O., Logan, P., Booth, V., Robinson, K., Lunt, E., Godfrey, D., Caswell, A., Kerr, M., Ollivere, B., Gordon, A.L., Piasecki, M., and CHADBORN, NEIL
Subjects: Bio/Medical/Health - Public Health, Health Services and Primary Care, Global Research Theme - Health and Wellbeing, Sarcopenia, Frailty, Immobility, Electrical Stimulation, Protein supplementation, Bio/Medical/Health - Clinical Medicine, Collaboration for Leadership in Applied Health Research and Care East Midlands
Abstract: East Midlands Research into Ageing Network (EMRAN) is a research collaboration across the East Midlands to facilitate collaborative applied clinical research into ageing and the care of older people. EMRAN was set up by NIHR CLAHRC East Midlands and is supported by the NIHR Clinical Research Network.

40. The Influence of an Alteration in Diet Composition on Plasma and Muscle Glutamine Levels in Man

Author: Greenhaff, P.L., primary, Gleeson, M., additional, and Maughan, R.J., additional
Published: 1988
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41. Dietary supplements for athletes: Emerging trends and recurring themes.

Author: Maughan, R.J., Greenhaff, P.L., and Hespel, P.
Subjects: *ATHLETES, *ATHLETIC ability, *COST effectiveness, *CREATINE, *DIETARY supplements, *DOPING in sports, *DRUG use testing, *NITRATES, *GOVERNMENT regulation
Abstract: Dietary supplements are widely used at all levels of sport. Changes in patterns of supplement use are taking place against a background of changes in the regulatory framework that governs the manufacture and distribution of supplements in the major markets. Market regulation is complicated by the increasing popularity of Internet sales. The need for quality control of products to ensure they contain the listed ingredients in the stated amount and to ensure the absence of potentially harmful substances is recognized. This latter category includes compounds prohibited under anti-doping regulations. Several certification programmes now provide testing facilities for manufacturers of both raw ingredients and end products to ensure the absence of prohibited substances. Athletes should carry out a cost–benefit analysis for any supplement they propose to use. For most supplements, the evidence is weak, or even completely absent. A few supplements, including caffeine, creatine, and bicarbonate, are supported by a strong research base. Difficulties arise when new evidence appears to support novel supplements: in recent years, β-alanine has become popular, and the use of nitrate and arginine is growing. Athletes seldom wait until there is convincing evidence of efficacy or of safety, but caution is necessary to minimize risk. [ABSTRACT FROM PUBLISHER]
Published: 2011
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