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4. Abstract 18307: The Pediatric Heart Network Digital Normal ECG Database: Measurements of Left Ventricular Hypertrophy Vary by Sex and Race

Author

Saarel, Elizabeth V, Granger, Suzanne, John, Kaltman R, Minich, LuAnn L, Tristani-Firouzi, Martin, Kim, Jeffrey, Ash, Kathleen E, Tsao, Sabrina, Berul, Charles I, Stephenson, Elizabeth A, Gamboa, David, Trachtenberg, Felicia, Fischbach, Peter, Vetter, Victoria L, Czosek, Richard, Johnson, Tiffanie R, Salerno, Jack C, Cain, Nicole, Pass, Robert H, Zeltser, Ilana, Silver, Eric S, Kovach, Joshua R, and Alexander, Mark E

Published
2017

5. Abstract 15546: Echo Z-Scores Adjusted for Body Surface Area Are Not Affected by Age, Sex, or Race: The Pediatric Heart Network Normal Echo Database

Author

Lopez, Leo, Colan, Steven D, Stylianou, Mario, Granger, Suzanne, Trachtenberg, Felicia L, Frommelt, Peter C, Pearson, Gail D, Camarda, Joseph A, Cnota, James F, Cohen, Meryl S, Dragulescu, Andreea, Frommelt, Michele A, Garuba, Olukayode David, Johnson, Tiffanie R, Lai, Wyman W, Mahgerefteh, Joseph, Pignatelli, Ricardo, Prakash, Ashwin, Sachdeva, Ritu, Soriano, Brian D, Soslow, Jonathan H, Spurney, Christopher, Srivastava, Shubhika, Taylor, Carolyn L, Thankavel, Poonam P, van der Velde, Mary E, Minich, L. LuAnn, and For the PHN Investigators, Echo Z-Score

Published
2017

6. Relationship of Echocardiographic Z Scores Adjusted for Body Surface Area to Age, Sex, Race, and Ethnicity: The Pediatric Heart Network Normal Echocardiogram Database

Author

Lopez, Leo, Colan, Steven, Stylianou, Mario, Granger, Suzanne, Trachtenberg, Felicia, Frommelt, Peter, Pearson, Gail, Camarda, Joseph, Cnota, James, Cohen, Meryl, Dragulescu, Andreea, Frommelt, Michele, Garuba, Olukayode, Johnson, Tiffanie, Lai, Wyman, Mahgerefteh, Joseph, Pignatelli, Ricardo, Prakash, Ashwin, Sachdeva, Ritu, Soriano, Brian, Soslow, Jonathan, Spurney, Christopher, Srivastava, Shubhika, Taylor, Carolyn, Thankavel, Poonam, van der Velde, Mary, and Minich, LuAnn

Published
2017
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10. Assessment of Growth 6 Years after the Norwood Procedure

Author

Burch, Phillip T., Ravishankar, Chitra, Newburger, Jane W., Lambert, Linda M., Pemberton, Victoria L., Granger, Suzanne, Floh, Alejandro A., Anderson, Jeffrey B., Hill, Garick D., Hill, Kevin D., Oster, Matthew E., Lewis, Alan B., Schumacher, Kurt R., Zyblewski, Sinai C., Davies, Ryan R., Jacobs, Jeffrey P., Lai, Wyman W., and Minich, LuAnn L.

Published
2017
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11. Effects of Red-Cell Storage Duration on Patients Undergoing Cardiac Surgery

Author

Steiner, Marie E., Ness, Paul M., Assmann, Susan F., Triulzi, Darrell J., Sloan, Steven R., Delaney, Meghan, Granger, Suzanne, Bennett-Guerrero, Elliott, Blajchman, Morris A., Scavo, Vincent, Carson, Jeffrey L., Levy, Jerrold H., Whitman, Glenn, DʼAndrea, Pamela, Pulkrabek, Shelley, Ortel, Thomas L., Bornikova, Larissa, Raife, Thomas, Puca, Kathleen E., Kaufman, Richard M., Nuttall, Gregory A., Young, Pampee P., Youssef, Samuel, Engelman, Richard, Greilich, Philip E., Miles, Ronald, Josephson, Cassandra D., Bracey, Arthur, Cooke, Rhonda, McCullough, Jeffrey, Hunsaker, Robert, Uhl, Lynne, McFarland, Janice G., Park, Yara, Cushing, Melissa M., Klodell, Charles T., Karanam, Ravindra, Roberts, Pamela R., Dyke, Cornelius, Hod, Eldad A., and Stowell, Christopher P.

Published
2015
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13. Dose of prophylactic platelet transfusions and prevention of hemorrhage

Author

Slichter, Sherrill J., Assmann, Susan F., Kaufman, Richard M., McCullough, Jeffrey, Triulzi, Darrell J., Strauss, Ronald G., Ness, Paul M., Gernsheimer, Terry B., Brecher, Mark E., Josephson, Cassandra D., Konkle, Barbara A., Ortel, Thomas L., Hillyer, Christopher D., Skerrett, Donna L., Woodson, Robert D., McCrae, Keith R., Sloan, Steven R., Uhl, Lynne, George, James N., Aquino, Victor M., Manno, Catherine S., Hess, John R., Leissinger, Cindy, Granger, Suzanne, and McFarland, Janice G.

Subjects
Hemorrhage -- Prevention, Thrombocytopenia -- Care and treatment
Abstract

A study was conducted to evaluate the efficacy of platelet dose of prophylactic in the prevention of bleeding or hemorrhage in patients with hypoproliferative thrombocytopenia. Results indicated that only low doses of platelet transfusions led to a reduction in bleeding.

Published
2010

15. Lasca herbarium

Author

Granger, Suzanne L. and Missouri Botanical Garden, Peter H. Raven Library

Subjects
Arboretum of Los Angeles County -- Herbarium
Published
1977

19. Green treasures emerge from dry lake

Author

Granger, Suzanne L. and Missouri Botanical Garden, Peter H. Raven Library

Subjects
Ecological succession, Pond ecology, Ponds -- California -- Arcadia, Seeds -- Dispersal
Published
1989

21. Challenges With Left Ventricular Functional Parameters: The Pediatric Heart Network Normal Echocardiogram Database

Author

Frommelt, Peter C., primary, Minich, L. LuAnn, additional, Trachtenberg, Felicia L., additional, Altmann, Karen, additional, Camarda, Joseph, additional, Cohen, Meryl S., additional, Colan, Steven D., additional, Dragulescu, Andreea, additional, Frommelt, Michele A., additional, Johnson, Tiffanie R., additional, Kovalchin, John P., additional, Lin, Lina, additional, Mahgerefteh, Joseph, additional, Nutting, Arni, additional, Parra, David A., additional, Pearson, Gail D., additional, Pignatelli, Ricardo, additional, Sachdeva, Ritu, additional, Soriano, Brian D., additional, Spurney, Christopher, additional, Srivastava, Shubhika, additional, Statile, Christopher J., additional, Stelter, Jessica, additional, Stylianou, Mario, additional, Thankavel, Poonam P., additional, Tierney, E. Seda, additional, van der Velde, Mary E., additional, Lopez, Leo, additional, Burns, Kristin, additional, Kaltman, Jonathan, additional, Pearson, Gail, additional, Pemberton, Victoria, additional, Mahony, Lynn, additional, Chen, Shan, additional, Colan, Steven, additional, Gallagher, Dianne, additional, Gerstenberger, Eric, additional, Gongwer, Russell, additional, Granger, Suzanne, additional, Keosaian, Julia, additional, Langley, Susanne, additional, Mansolf, Tammi, additional, Moine, Stephanie, additional, Morrison, Andrew, additional, Nelson, Katelyn, additional, Ni, Brenda, additional, Ortiz, Janet, additional, Pober, David, additional, Pucillo, Michelle, additional, Stark, Paul, additional, Toomey, Christiana, additional, Trachtenberg, Felicia, additional, Winrich, Barbara, additional, Schwartz, Steven, additional, Golding, Fraser, additional, McCrindle, Brian, additional, Radojewski, Elizabeth, additional, Mital, Seema, additional, Walter, Patricia, additional, Slorach, Cameron, additional, Newburger, Jane, additional, Triedman, John, additional, Prakash, Ashwin, additional, Levine, Jami, additional, Paridon, Stephen, additional, Cohen, Meryl, additional, Goldberg, David, additional, Morrison, Tonia, additional, Atz, Andrew M., additional, Graham, Eric, additional, Taylor, Carolyn, additional, Chowdhury, Shahryar, additional, Infinger, Patricia, additional, LuAnn Minich, L., additional, Williams, Richard V., additional, Truong, Dongngan T., additional, Lambert, Linda M., additional, Shearrow, Marian E., additional, Stanton, Belva, additional, Goldberg, Caren, additional, Ohye, Richard, additional, Welch, Suzanne, additional, Cnota, James F., additional, Hamstra, Michelle, additional, Ash, Kathleen, additional, Sticka, Joshua, additional, Payne, Mark, additional, Cordes, Timothy, additional, Swan, Liz, additional, Mahle, William, additional, Friedman, Heather S., additional, Clark, Laurie J., additional, Penny, Daniel, additional, Garuba, David, additional, Altman, Carolynn, additional, Richmond, Marc, additional, Lai, Wyman, additional, Korsin, Rosalind, additional, Anderson, Brett, additional, Thankavel, Poonam Punjwani, additional, Carron, Hollie, additional, Ginde, Salil, additional, Otto, Michelle, additional, Frommelt, Michele, additional, Markham, Larry, additional, Soslow, Jonathan H., additional, Young, Luciana, additional, Duffy, Elise, additional, Van't Hof, Kathleen, additional, Lewin, Mark, additional, Lester, Joel, additional, Bhat, Aarti H., additional, Payne, Amy, additional, Lytrivi, Irene, additional, Ko, Helen, additional, Balem, Kelly Ann, additional, Sable, Craig, additional, Frommelt, Peter, additional, Hartsig, Hannah, additional, Artman, Michael, additional, Rao, Anu, additional, Eidem, Ben, additional, Matherne, G. Paul, additional, Feltes, Timothy, additional, Johnson, Julie, additional, Krischer, Jeffrey P., additional, McBride, Patrick, additional, Kugler, John, additional, Evans, Frank, additional, Driscoll, David, additional, Galantowicz, Mark, additional, Hunsberger, Sally, additional, Knight, Thomas, additional, and Taylor, Holly, additional

Published
2019
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22. Assessment of Growth Six Years after the Norwood Procedure

Author

Burch, Phillip T., Ravishankar, Chitra, Newburger, Jane W., Lambert, Linda M., Pemberton, Victoria L., Granger, Suzanne, Floh, Alejandro A., Anderson, Jeffrey B., Hill, Garick D., Hill, Kevin D., Oster, Matthew E., Lewis, Alan B., Schumacher, Kurt R., Zyblewski, Sinai C., Davies, Ryan R., Jacobs, Jeffrey P., Lai, Wyman W., and Minich, L. LuAnn

Subjects
Male, Time Factors, Body Weight, Infant, Newborn, Growth, Norwood Procedures, Article, Body Height, Body Mass Index, Hypoplastic Left Heart Syndrome, Humans, Female, Child, Follow-Up Studies
Abstract

At 6 years of age, patients with hypoplastic left heart syndrome had mean age-adjusted z-scores for weight and height below the normative population, and body mass index was similar to the normative population. Males had the greatest increase in z-scores for body mass index.ClinicalTrials.gov: NCT00115934.

Published
2016

23. Effects of Red-Cell Storage Duration on Patients Undergoing Cardiac Surgery

Author

Josephson, Cassandra D., Assmann, Susan F., Young, Pampee P., Ness, Paul M., Youssef, Samuel, Carson, Jeffrey L., McCullough, Jeffrey, Delaney, Meghan, D’Andrea, Pamela, Levy, Jerrold H., Cooke, Rhonda, Scavo, Vincent, Granger, Suzanne, Sloan, Steven R., Bracey, Arthur, Miles, Ronald, Puca, Kathleen E., Ortel, Thomas L., Bornikova, Larissa, Kaufman, Richard M., Hunsaker, Robert, Pulkrabek, Shelley, Triulzi, Darrell J., Nuttall, Gregory A., Raife, Thomas, Engelman, Richard, Steiner, Marie E., Whitman, Glenn, Blajchman, Morris A., Uhl, Lynne, Bennett-Guerrero, Elliott, and Greilich, Philip E.

Abstract

Some observational studies have reported that transfusion of red-cell units that have been stored for more than 2 to 3 weeks is associated with serious, even fatal, adverse events. Patients undergoingcardiac surgery may be especially vulnerable to the adverse effects of transfusion.

Published
2015
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24. Platelet Transfusion Practices Among Very-Low-Birth-Weight Infants

Author

Sparger, Katherine A., primary, Assmann, Susan F., additional, Granger, Suzanne, additional, Winston, Abigail, additional, Christensen, Robert D., additional, Widness, John A., additional, Josephson, Cassandra, additional, Stowell, Sean R., additional, Saxonhouse, Matthew, additional, and Sola-Visner, Martha, additional

Published
2016
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25. LONGITUDINAL ASSESSMENT OF GROWTH 6 YEARS AFTER THE NORWOOD OPERATION: RESULTS FROM THE SINGLE VENTRICLE RECONSTRUCTION TRIAL

Author

Burch, Phillip Todd, primary, Ravishankar, Chitra, additional, Newburger, Jane, additional, Lambert, Linda, additional, Pemberton, Victoria, additional, Granger, Suzanne, additional, Floh, Alejandro, additional, Anderson, Jeffrey, additional, Hill, Garick, additional, Hill, Kevin, additional, Oster, Matthew, additional, Davies, Ryan, additional, Jacobs, Jeffrey, additional, Lai, Wyman, additional, Lewis, Alan, additional, Schumacher, Kurt, additional, Zyblewski, Sinai, additional, and Minich, L. LuAnn, additional

Published
2016
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27. Rituximab for treatment of inhibitors in haemophilia A

Author

Leissinger, Cindy, primary, Josephson, Cassandra, primary, Konkle, Barbara, primary, Kruse-Jarres, Rebecca, primary, Ragni, Margaret, primary, Journeycake, Janna, primary, Valentino, Leonard, primary, Key, Nigel, primary, Gill, Joan, primary, McCrae, Keith, primary, Neufeld, Ellis, primary, Manno, Catherine, primary, Raffini, Leslie, primary, Saxena, Kapil, primary, Torres, Marcela, primary, Marder, Victor, primary, Bennett, Carolyn, primary, Assmann, Susan, primary, and Granger, Suzanne, additional

Published
2014
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29. Phase II Trial of Rituximab in the Treatment of Inhibitors in Congenital Hemophilia A: Results of the RICH Study

Author

Leissinger, Cindy A., primary, Kruse-Jarres, Rebecca, additional, Granger, Suzanne, additional, Konkle, Barbara A, additional, Ragni, Margaret V., additional, Journeycake, Janna M., additional, Neufeld, Ellis J., additional, Josephson, Cassandra, additional, Bennett, Carolyn M., additional, Valentino, Leonard A., additional, Key, Nigel S., additional, Raffini, Leslie, additional, Torres, Marcela, additional, Gill, Joan Cox, additional, and Assmann, Susan, additional

Published
2011
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30. Multilaboratory Evaluation of Real-Time PCR Tests for Hepatitis B Virus DNA Quantification

Author

Caliendo, Angela M., primary, Valsamakis, Alexander, additional, Bremer, James W., additional, Ferreira-Gonzalez, Andrea, additional, Granger, Suzanne, additional, Sabatini, Linda, additional, Tsongalis, Gregory J., additional, Wang, Yun F. (Wayne), additional, Yen-Lieberman, Belinda, additional, Young, Steve, additional, and Lurain, Nell S., additional

Published
2011
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37. Stroke Prevention Trial in Sickle Cell Anemia (STOP): extended follow-up and final results

Author

Lee, Margaret T., Piomelli, Sergio, Granger, Suzanne, Miller, Scott T., Harkness, Shannon, Brambilla, Donald J., and Adams, Robert J.

Abstract

The Stroke Prevention Trial in Sickle Cell Anemia (STOP) was a randomized trial to evaluate whether chronic transfusion could prevent initial stroke in children with sickle-cell anemia at high risk as determined by transcranial Doppler (TCD). The trial demonstrated a large benefit of transfusion and was halted early. After termination of the trial, patients participated in a posttrial follow-up study. More patients in the transfusion group (70%) elected transfusion for primary stroke prevention compared with those on standard care (45%). Six patients with persistently abnormal TCD results developed stroke. A minority with initially abnormal TCD results remained stroke-free without transfusion. Except for lower baseline and follow-up TCD velocities compared with those with stroke, no predictive features of this apparent lower-risk subgroup could be determined. TCD results at last testing in 108 patients that did not have stroke were: normal (44.4%), conditional (26.9%), abnormal (22.2%), and inadequate (6.5%). Patients on transfusion were more likely to have normal TCD results. Transfusion resulted in iron overload and alloimmunization, but no infection. The study provides new information on acceptance rates and long-term effects of transfusion. Persistent TCD elevation signals ongoing stroke risk. Reduction in TCD results over time without transfusion is observed in some patients and requires further study.

Published
2006
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38. Bone Marrow Cellularity Determination: Comparison of the Biopsy, Aspirate, and Buffy Coat

Author

Gruppo, Ralph A., Lampkin, Beatrice C., and Granger, Suzanne

Abstract

Bone marrow biopsies (244) performed with a Jamshidi needle were evaluated in 53 children with leukemia or aplastic anemia. Adequate specimens were obtained in 85%. Results of cellularity estimated by biopsy were compared to the cellularity of the aspirate versus volumetric determination of the myeloid-erythroid layer (buffy coat). A wide discrepancy was noted between marrow cellularity confirmed by biopsy versus the aspirate or buffy coat. The greatest variance was seen in the hypercellular or normocellular marrows, as estimated by biopsy, in which 39% were misinterpreted as moderately or severely hypocellular by aspirate. Volumetric measurement of buffy coat was least acceptable for estimating cellularity. Thus the biopsy has proved to be an important and reliable indicator of bone marrow cellularity.

Published
1977
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39. Electrocardiograms in Healthy North American Children in the Digital Age.

Author

Saarel, Elizabeth V., Granger, Suzanne, Kaltman, Jonathan R., Minich, L. LuAnn, Tristani-Firouzi, Martin, Kim, Jeffrey J., Ash, Kathleen, Tsao, Sabrina S., Berul, Charles I., Stephenson, Elizabeth A., Gamboa, David G., Trachtenberg, Felicia, Fischbach, Peter, Vetter, Victoria L., Czosek, Richard J., Johnson, Tiffanie R., Salerno, Jack C., Cain, Nicole B., Pass, Robert H., and Zeltser, Ilana

Abstract

Background: Interpretation of pediatric ECGs is limited by lack of accurate sex- and race-specific normal reference values obtained with modern technology for all ages. We sought to obtain contemporary digital ECG measurements in healthy children from North America, to evaluate the effects of sex and race, and to compare our results to commonly used published datasets.Methods: Digital ECGs (12-lead) were retrospectively collected for children ≤18 years old with normal echocardiograms at 19 centers in the Pediatric Heart Network. Patients were classified into 36 groups: 6 age, 2 sex, and 3 race (white, black, and other/mixed) categories. Standard intervals and amplitudes were measured; mean±SD and 2nd/98th percentiles were determined by age group, sex, and race. For each parameter, multivariable analysis, stratified by age, was conducted using sex and race as predictors. Parameters were compared with 2 large pediatric ECG data sets.Results: Among ECGs from 2400 children, significant differences were found by sex and race categories. The corrected QT interval in lead II was greater for girls compared with boys for age groups ≥3 years (P≤0.03) and for whites compared with blacks for age groups ≥12 years (P<0.05). The R wave amplitude in V6 was greater for boys compared with girls for age groups ≥12 years (P<0.001), for blacks compared with white or other race categories for age groups ≥3 years (P≤0.006), and greater compared with a commonly used public data set for age groups ≥12 years (P<0.0001).Conclusions: In this large, diverse cohort of healthy children, most ECG intervals and amplitudes varied by sex and race. These differences have important implications for interpreting pediatric ECGs in the modern era when used for diagnosis or screening, including thresholds for left ventricular hypertrophy. [ABSTRACT FROM AUTHOR]

Published
2018
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40. Relationship of Echocardiographic ZScores Adjusted for Body Surface Area to Age, Sex, Race, and Ethnicity

Author

Lopez, Leo, Colan, Steven, Stylianou, Mario, Granger, Suzanne, Trachtenberg, Felicia, Frommelt, Peter, Pearson, Gail, Camarda, Joseph, Cnota, James, Cohen, Meryl, Dragulescu, Andreea, Frommelt, Michele, Garuba, Olukayode, Johnson, Tiffanie, Lai, Wyman, Mahgerefteh, Joseph, Pignatelli, Ricardo, Prakash, Ashwin, Sachdeva, Ritu, Soriano, Brian, Soslow, Jonathan, Spurney, Christopher, Srivastava, Shubhika, Taylor, Carolyn, Thankavel, Poonam, van der Velde, Mary, and Minich, LuAnn

Abstract

Supplemental Digital Content is available in the text.

Published
2017
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