105 results on '"Gouveia Peluzio, Maria do Carmo"'
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2. Ceftriaxone causes dysbiosis and changes intestinal structure in adjuvant obesity treatment
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Aparecida dos Reis Louzano, Sandra, de Moura e Dias, Mariana, Lopes da Conceição, Lisiane, Antônio de Oliveira Mendes, Tiago, and Gouveia Peluzio, Maria do Carmo
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- 2022
- Full Text
- View/download PDF
3. Antibiotic Followed by a Potential Probiotic Increases Brown Adipose Tissue, Reduces Biometric Measurements, and Changes Intestinal Microbiota Phyla in Obesity
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de Moura e Dias, Mariana, dos Reis Louzano, Sandra Aparecida, da Conceição, Lisiane Lopes, da Conceição Fernandes, Rayssa, de Oliveira Mendes, Tiago Antônio, Pereira, Solange Silveira, de Oliveira, Leandro Licursi, and Gouveia Peluzio, Maria do Carmo
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- 2021
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4. Prophylactic and therapeutic supplementation using fructo-oligosaccharide improves the intestinal homeostasis after mucositis induced by 5- fluorouracil
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Carvalho, Paula Lopes Armond, Andrade, Maria Emília Rabelo, Trindade, Luísa Martins, Leocádio, Paola Caroline Lacerda, Alvarez-Leite, Jacqueline Isaura, dos Reis, Diego Carlos, Cassali, Geovanni Dantas, Souza e Melo, Éricka Lorenna de Sales, dos Santos Martins, Flaviano, Fernandes, Simone Odília Antunes, Gouveia Peluzio, Maria do Carmo, Generoso, Simone de Vasconcelos, and Cardoso, Valbert Nascimento
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- 2021
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5. Beneficial effects of butyrate on brain functions: A view of epigenetic.
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Ávila Alpinoa, Gabriela de Cássia, Amorim Pereira-Sol, Gabriela, de Moura e Dias, Mariana, Silva de Aguiar, Aline, and Gouveia Peluzio, Maria do Carmo
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BUTYRATES ,SODIUM butyrate ,SHORT-chain fatty acids ,PSYCHOTHERAPY ,EPIGENETICS ,HISTONES ,GUT microbiome - Abstract
Brain functions are influenced by the presence, activity, and metabolism of the gut microbiota through the gut-microbiota-brain (GMB) axis. The consumption of a fiber-rich diet increases the content of short-chain fatty acids (SCFAs) from bacterial fermentation in the colon. Among SCFAs, butyrate stands out because of its wide array of biological functions, such as ability to influence brain functions. Pharmacologically, sodium butyrate (NaB) regulates gene expression in the brain, where it has several beneficial effects ranging from neurodegenerative diseases to behavioral disorders through inhibitors of histone deacetylases (HDACis). In this context, we review the mechanisms of action of the two types of butyrate on brain functions, with an emphasis on the epigenetic approach. Both types of butyrate are potentially interesting for the prevention and adjuvant therapy of neurological and psychological disorders due to their neuroprotective functions. However, further studies are needed to investigate the possible neuroepigenetic effects of butyrate derived from bacterial fermentation. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Diet-induced obesity in animal models: points to consider and influence on metabolic markers
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de Moura e Dias, Mariana, dos Reis, Sandra Aparecida, da Conceição, Lisiane Lopes, Sediyama, Catarina Maria Nogueira de Oliveira, Pereira, Solange Silveira, de Oliveira, Leandro Licursi, Gouveia Peluzio, Maria do Carmo, Martinez, J. Alfredo, and Milagro, Fermín Ignacio
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- 2021
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7. Synbiotic VSL#3 and yacon-based product modulate the intestinal microbiota and prevent the development of pre-neoplastic lesions in a colorectal carcinogenesis model
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dos Santos Cruz, Bruna Cristina, da Silva Duarte, Vinícius, Giacomini, Alessio, Corich, Viviana, de Paula, Sérgio Oliveira, da Silva Fialho, Lilian, Guimarães, Valéria Monteze, de Luces Fortes Ferreira, Célia Lúcia, and Gouveia Peluzio, Maria do Carmo
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- 2020
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8. Consumption of virgin coconut oil in Wistar rats increases saturated fatty acids in the liver and adipose tissue, as well as adipose tissue inflammation
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de Moura e Dias, Mariana, Pais Siqueira, Nathane, Lopes da Conceição, Lisiane, Aparecida dos Reis, Sandra, Xavier Valente, Flávia, Maciel dos Santos Dias, Manoela, de Oliveira Barbosa Rosa, Carla, Oliveira de Paula, Sérgio, da Matta, Sérgio Luís Pinto, Licursi de Oliveira, Leandro, Bressan, Josefina, and Gouveia Peluzio, Maria do Carmo
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- 2018
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9. Anti-inflammatory pathways of kefir in murine model: a systematic review
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Albuquerque Pereira, Mariana de Fátima, primary, Matias Albuini, Fernanda, additional, and Gouveia Peluzio, Maria do Carmo, additional
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- 2023
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10. Consumption of extra virgin olive oil improves body composition and blood pressure in women with excess body fat: a randomized, double-blinded, placebo-controlled clinical trial
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Galvão Cândido, Flávia, Xavier Valente, Flávia, da Silva, Laís Emilia, Gonçalves Leão Coelho, Olívia, Gouveia Peluzio, Maria do Carmo, and Gonçalves Alfenas, Rita de Cássia
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- 2018
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11. The role of IL-10 in regulating inflammation and gut microbiome in mice consuming milk kefir and orally challenged with S. Typhimurium
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Albuquerque Pereira, Mariana de Fátima, primary, Morais de Ávila, Larissa Gabriela, additional, dos Santos Cruz, Bruna Cristina, additional, Campos Silva, Bruno, additional, Licursi de Oliveira, Leandro, additional, Vilela Gonçalves, Reggiani, additional, de Oliveira Barros Ribon, Andrea, additional, de Oliveira Mendes, Tiago Antônio, additional, and Gouveia Peluzio, Maria do Carmo, additional
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- 2023
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12. Treinamento em corrida de baixa intensidade: propriedades estruturais e mecânicas da epífise proximal do fêmur de ratas osteopênicas
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Fernandes Maia, Bárbara Braga, Del Carlo, Ricardo Junqueira, Drummond, Lucas Rios, Gouveia Pelúzio, Maria do Carmo, Osório Silva, Carlos Henrique, Quirino Louzada, Mário Jefferson, Quintão Junior, Judson Fonseca, Lavorato, Victor Neiva, Soares Ramos, Regiane Maria, and Natali, Antônio José
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- 2014
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13. Faecal levels of Bifidobacterium and Clostridium coccoides but not plasma lipopolysaccharide are inversely related to insulin and HOMA index in women
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F.S.Teixeira, T., Grześkowiak, Łukasz M., Salminen, Seppo, Laitinen, Kirsi, Bressan, Josefina, and Gouveia Peluzio, Maria do Carmo
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- 2013
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14. FADS1 and FADS2 Gene Polymorphisms Modulate the Relationship of Omega-3 and Omega-6 Fatty Acid Plasma Concentrations in Gestational Weight Gain: A NISAMI Cohort Study
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Santana, Jerusa da Mota, primary, Pereira, Marcos, additional, Carvalho, Gisele Queiroz, additional, Gouveia Peluzio, Maria do Carmo, additional, Drumond Louro, Iúri, additional, Santos, Djanilson Barbosa dos, additional, and Oliveira, Ana Marlucia, additional
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- 2022
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15. Ceftriaxone causes dysbiosis and changes intestinal structure in adjuvant obesity treatment
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Aparecida dos Reis Louzano, Sandra, primary, de Moura e Dias, Mariana, additional, Lopes da Conceição, Lisiane, additional, Antônio de Oliveira Mendes, Tiago, additional, and Gouveia Peluzio, Maria do Carmo, additional
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- 2021
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16. Liver Biomarkers and Their Applications to Nutritional Interventions in Animal Studies
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de Castro, Cynthia Aparecida, primary, Maciel dos Santos Dias, Manoela, additional, da Silva, Karina Ana, additional, dos Reis, Sandra Aparecida, additional, Lopes da Conceição, Lisiane, additional, De Nadai Marcon, Letícia, additional, de Sousa Moraes, Luis Fernando, additional, and Gouveia Peluzio, Maria do Carmo, additional
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- 2015
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17. Maintenance of Probiotic Characteristics of Dry Kefir: Is It Possible?
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Brasiel, Poliana Guiomar De Almeida, Costa de Almeida, Thaís, Mateus, Kácia, Fernandes de Carvalho, Antônio, Potente Dutra Luquetti, Sheila Cristina, and Gouveia Peluzio, Maria Do Carmo
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KEFIR ,LACTIC acid bacteria ,SPRAY drying ,MANUFACTURING processes ,EXTRACELLULAR matrix proteins ,PROBIOTICS - Abstract
Kefir is a natural probiotic containing a complex mixture of bacteria and yeast associated in a matrix composed of protein and polysaccharide, and to it are attributed several beneficial properties to health. In this study, we have investigated the effect of kefir drying on the microbiological counts of lactic acid bacteria and yeasts. The viable bacteria and yeast counts in dry kefir were reduced when compared to fresh kefir 6.46 log cfu/g and 4.14 log cfu/g, respectively.. Thus, it was possible to maintain sufficient stability of microbes in the powdered product, indicating that industrial processing may contribute to the viability and survival of probiotic bacteria. Despite the technological challenges, the spray drying of kefir seems to be a promising method for the use of this probiotic complex on a larger scale. [ABSTRACT FROM AUTHOR]
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- 2022
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18. Microbial community dynamics of fermented kefir beverages changes over time
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de Almeida Brasiel, Poliana Guiomar, primary, Dutra Medeiros, Julliane, additional, Barbosa Ferreira Machado, Alessandra, additional, Schuchter Ferreira, Maíra, additional, Gouveia Peluzio, Maria do Carmo, additional, and Potente Dutra Luquetti, Sheila Cristina, additional
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- 2021
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19. Maintenance of Probiotic Characteristics of Dry Kefir: Is It Possible?
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Brasiel, Poliana Guiomar De Almeida, primary, Costa de Almeida, Thaís, additional, Mateus, Kácia, additional, Fernandes de Carvalho, Antônio, additional, Potente Dutra Luquetti, Sheila Cristina, additional, and Gouveia Peluzio, Maria Do Carmo, additional
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- 2020
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20. Chemoprevention of DMH-Induced Early Colon Carcinogenesis in Male BALB/c Mice by Administration of Lactobacillus Paracasei DTA81
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da Silva Duarte, Vinícius, primary, dos Santos Cruz, Bruna Cristina, additional, Tarrah, Armin, additional, Sousa Dias, Roberto, additional, de Paula Dias Moreira, Luiza, additional, Lemos Junior, Wilson José Fernandes, additional, Fidélis Silva, Lívia Carneiro, additional, Rocha Santana, Gabriele, additional, Licursi de Oliveira, Leandro, additional, Gouveia Peluzio, Maria do Carmo, additional, Mantovani, Hilario Cuquetto, additional, Corich, Viviana, additional, Giacomini, Alessio, additional, and de Paula, Sérgio Oliveira, additional
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- 2020
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21. Soybean Oil: How Good or How Bad in Comparison with Other Dietary Oils in the Context of Colon Cancer
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Salles Teixeira, Tatiana Fiche, primary, Boroni Moreira, Ana Paula, additional, Diniz, Damiana, additional, and Gouveia Peluzio, Maria do Carmo, additional
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- 2011
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22. The effect of a breakfast's glycaemic index and type of hydration on metabolism and cycling performance: a crossover, randomized, controlled clinical trial.
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de Melo Cazal, Mariana, de Cássia Gonçalves Alfenas, Rita, Gouveia Peluzio, Maria do Carmo, dos Santos Amorim, Paulo Roberto, Alvez Tomaz, Priscila, and Carlos Marins, João Bouzas
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BREAKFASTS ,GLYCEMIC index ,CARBOHYDRATE content of food ,METABOLIC regulation ,CYCLISTS -- Nutrition - Abstract
Copyright of RICYDE. Revista Internacional de Ciencias del Deporte is the property of Revista Internacional de Ciencias del Deporte and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2021
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23. "A mesa que encolheu": a perspectiva alimentar das mães que perderam filhos.
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Fialho de Sousa, Maria Teresa, Gouveia Peluzio, Maria do Carmo, de Souza Melo, Mônica Santos, Simonini, Eduardo, Gontijo Coelho, France Maria, and Amaral Araújo, Raquel Maria
- Abstract
Copyright of Revista Ciência & Saúde Coletiva is the property of Associacao Brasileira de Pos-Graduacao em Saude Coletiva and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2020
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- View/download PDF
24. Lifestyle and vitamin D dosage in women with breast cancer
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Nogueira Oliveira-Sediyama, Catarina Maria, Dias, Manoela Maciel dos Santos, Pessoa, Milene Cristine, Ribeiro Queiroz, Andréia, Gomes Suhett, Lara, Nascimento Freitas, Renata, Oliveira de Paula, Sérgio, and Gouveia Peluzio, Maria do Carmo
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Breast cancer ,Cáncer de mama ,Physical activity ,Vitamina D ,Actividad física ,Case-control study ,Menopausia ,Vitamin D ,Menopause ,Estudio de casos y controles - Abstract
Introduction: The prevention strategy of breast cancer is still the key factor for early diagnosis and the most effective method for tracking the disease. Objective: This study aimed to evaluate the association vitamin D level with breast cancer in women. Methods: This hospital case-control study was conducted with 181 women with breast cancer and 197 healthy controls. Vitamin D status, calcium, phosphorus and PTH serum dosage and data collection related to lifestyle and patient's history, besides anthropometric measurements were performed. Univariate analysis (Chi-square and raw odds ratio) and multivariate analysis were performed through multivariate logistic regression. Results: This study shows a higher value of vitamin D in health controls (26.9 mg/dL) than in breast cancer women (24.8 mg/dL). Higher numbers of women with sufficient vitamin D status (34.85%) were found in control group than cancer group. Using the multiple logistic regression model, the family history of breast cancer (OR 36.37, 95%CI 4.75-278.50) and menopause (OR 5.17, 95% CI 2.72-9.80) had a direct association with breast cancer, while the level of vitamin D (OR 0.95, 95%CI 0.91-0.99) and moderate physical activity (OR 0.31, 95%CI 0.10-0.93) maintained the inverse associations with the disease. Conclusion: Vitamin D status and the practice of moderate physical activity were considered protective factors for breast cancer. However, menopause and family history of breast cancer were considered a risk factor for breast cancer. Introducción: la estrategia de prevención del cáncer de mama sigue siendo el factor clave para el diagnóstico precoz y el método más eficaz para el seguimiento de la enfermedad. Objetivo: este estudio tuvo como objetivo evaluar el nivel de vitamina D asociado con el cáncer de mama en las mujeres. Métodos: este estudio de casos y controles hospitalarios se llevó a cabo con 181 mujeres con cáncer de mama y 197 controles sanas. Se estudió el nivel de vitamina D, calcio, fósforo y la dosis de suero PTH; se recopilaron de datos relacionados con el estilo de vida y com la historia de las pacientes, además se realizaron mediciones antropométricas. El análisis univariante (Chi-cuadrado probabilidades y primas ratio) y el análisis multivariado se realizó mediante regresión logística multivariante. Resultados: este estudio muestra un valor más alto de vitamina D en los controles de salud (26,9 mg/dl) que en las mujeres con cáncer de mama (24,8 mg/dl). Se encontraron más mujeres con suficiente vitamina D (34,85%) en el grupo control que en el grupo de cáncer. Usando el modelo de regresión logística múltiple, la historia familiar de cáncer de mama (OR 36,37; IC del 95%: 4,75 a 278,50) y la menopausia (OR 5,17; IC del 95%: 2,72 a 9,80) se halló una relación directa con el cáncer de mama, mientras que el nivel de vitamina D (OR 0,95; IC del 95%: 0,91 a 0,99) y la actividad física moderada (OR 0,31; IC del 95%: 0,10 a 0,93) mantienen las asociaciones inversas con la enfermedad. Conclusión: el estado de vitamina D y la práctica de actividad física moderada se consideraron factores de protección para el cáncer de mama. Sin embargo, la menopausia y la historia familiar de cáncer de mama se consideran un factor de riesgo para el cáncer de mama.
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- 2016
25. Vitamin D insufficiency/deficiency is associated with insulin resistance in Brazilian children, regardless of body fat distribution
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Milagres, Luana Cupertino, primary, Rocha, Naruna Pereira, additional, Filgueiras, Mariana de Santis, additional, Albuquerque, Fernanda Martins de, additional, Castro, Ana Paula Pereira, additional, Pessoa, Milene Cristine, additional, Gouveia Peluzio, Maria do Carmo, additional, and Novaes, Juliana Farias de, additional
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- 2017
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26. Consumption of extra virgin olive oil improves body composition and blood pressure in women with excess body fat: a randomized, double-blinded, placebo-controlled clinical trial
- Author
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Galvão Cândido, Flávia, primary, Xavier Valente, Flávia, additional, da Silva, Laís Emilia, additional, Gonçalves Leão Coelho, Olívia, additional, Gouveia Peluzio, Maria do Carmo, additional, and Gonçalves Alfenas, Rita de Cássia, additional
- Published
- 2017
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27. Anthropometric profile, body composition and body image perception of adolescents with positive screening for eating disorders
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Stofeles Cecon, Roberta, primary, Castro Franceschini, Sylvia do Carmo, additional, Gouveia Peluzio, Maria do Carmo, additional, Miranda Hermsdorff, Helen Hermana, additional, and Priore, Silvia Eloiza, additional
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- 2017
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28. Chemical composition, characterization of anthocyanins and antioxidant potential of Euterpe edulis fruits: applicability on genetic dyslipidemia and hepatic steatosis in mice
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Marques Cardoso, Luciana, Dias Novaes, Rômulo, Castro, Cynthia Aparecida de, Azevedo Novello, Alexandre, Vilela Gonçalves, Reggiani, Ricci-Silva, Maria Esther, Ramos, Humberto Josué de Oliveira, Gouveia Peluzio, Maria do Carmo, and Viana Leite, João Paulo
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Anthocyanins ,Functional food ,Antocianinas ,Euterpe edulis ,Alimentacion funcional ,Arecaceae ,Liver disease ,Enfermedad hepática - Abstract
The significance of polyphenol intake for the prevention of chronic diseases is controversial. Objective: this study investigated the chemical composition and antioxidant potential of an anthocyanin-rich extract from Euterpe edulis fruits (LPEF) and its effects on liver steatosis in dyslipidemic apoE-/- knockout mice. Materials and methods: mice were divided into G1 (C57BL/6) standard diet; G2 (apoE-/-) standard diet, G3 (apoE-/-) 2% LPEF, G4 (apoE-/-) 6% LPEF, G5 (apoE-/-) 10% LPEF, G6 (apoE-/-) 2% α-tocopherol acetate. After 75 days of treatment, the animals were euthanized. The LPEF contained a high level of monomeric anthocyanins (301.4 mg/100g) and marked antioxidant activity. Results: Catalase activity was reduced in G3, G4, G5 and G6 compared to G2. Superoxide dismutase was reduced only in G4. The animals in G4, G5, and G6 showed low HDL and triglycerides levels compared to G2. The proportion of lipid droplets in liver tissue was reduced in G4 and G5 compared to G2, G3, and G6. Conclusion: The results indicated that E. edulis pulp is rich in anthocyanins and the LPEF dietary consumption can reduce the severity of liver steatosis in apoE-/- mice, an effect that is potentially mediated by the antioxidant activity of this extract and modulation of triglyceride serum levels. El papel de los polifenoles en la prevencion de enfermedades cronicas es controvertido. Objetivo: este estudio investigo la composicion quimica y el potencial antioxidante de un extracto del fruto de Euterpe edulis rico en antocianinas (LPEF) y sus efectos en la esteatosis hepatica en ratones apoE-/- knockout con dislipidemia. Material y metodos: los ratones fueron divididos en los siguientes grupos; G1 (C57BL/6) con una dieta estandar; G2 (apoE-/-) con dieta estandar; G3 G3 (apoE-/-) con 2% de LPEF; G4 (apoE-/-) con 6% de LPEF; G5 (apoE-/-) con 10% de LPEF y G6 (apoE-/-) con 2% acetato α-tocoferol (α-tocopherol acetate). Despues de 75 dias de tratamiento, los animales fueron eutanizados. El LPEF contenia un alto nivel de antocianinas monomericas (301,4 mg/100 g) con notable actividad antioxidante. Resultados: la actividad catalasa fue reducida en los grupos G3, G4, G5 y G6 comparada con G2. La superoxidasa dismutasa solo se redujo en el grupo G4. Los animales de G4, G5 y G6 mostraron bajos niveles de HDL trigliceridos, comparados con G2. La proporcion de lipidos en el tejido hepatico fue reducida en G4 y G5, comparado con G2, G3 y G6. Conclusion: los resultados indicaron que la pulpa de E. edulis es rica en antocianinas, y que el consumo de LPEF en la dieta puede reducir la severidad de la esteatosis hepatica en ratones apoE-/-, un efecto que es potencialmente mediado por la actividad antioxidante de este extracto y la modulacion en los niveles sericos de trigliceridos.
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- 2015
29. Chemical composition, characterization of anthocyanins and antioxidant potential of Euterpe edulis fruits: applicability on genetic dyslipidemia and hepatic steatosis in mice
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Marques Cardoso,Luciana, Dias Novaes,Rômulo, Castro,Cynthia Aparecida de, Azevedo Novello,Alexandre, Vilela Gonçalves,Reggiani, Ricci-Silva,Maria Esther, Ramos,Humberto Josué de Oliveira, Gouveia Peluzio,Maria do Carmo, and Viana Leite,João Paulo
- Subjects
Anthocyanins ,Functional food ,food and beverages ,lipids (amino acids, peptides, and proteins) ,Euterpe edulis ,Arecaceae ,Liver disease - Abstract
The significance of polyphenol intake for the prevention of chronic diseases is controversial. Objective: this study investigated the chemical composition and antioxidant potential of an anthocyanin-rich extract from Euterpe edulis fruits (LPEF) and its effects on liver steatosis in dyslipidemic apoE-/- knockout mice. Materials and methods: mice were divided into G1 (C57BL/6) standard diet; G2 (apoE-/-) standard diet, G3 (apoE-/-) 2% LPEF, G4 (apoE-/-) 6% LPEF, G5 (apoE-/-) 10% LPEF, G6 (apoE-/-) 2% α-tocopherol acetate. After 75 days of treatment, the animals were euthanized. The LPEF contained a high level of monomeric anthocyanins (301.4 mg/100g) and marked antioxidant activity. Results: Catalase activity was reduced in G3, G4, G5 and G6 compared to G2. Superoxide dismutase was reduced only in G4. The animals in G4, G5, and G6 showed low HDL and triglycerides levels compared to G2. The proportion of lipid droplets in liver tissue was reduced in G4 and G5 compared to G2, G3, and G6. Conclusion: The results indicated that E. edulis pulp is rich in anthocyanins and the LPEF dietary consumption can reduce the severity of liver steatosis in apoE-/- mice, an effect that is potentially mediated by the antioxidant activity of this extract and modulation of triglyceride serum levels.
- Published
- 2015
30. Prediction of body fat in adolescents: comparison of two electric bioimpedance devices with dual-energy X-ray absorptiometry
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Rodrigues de Faria, Eliane, Rocha de Faria, Franciane, Siqueira Santos Gonçalves, Vivian, Castro Franceschini, Sylvia do Carmo, Gouveia Peluzio, Maria do Carmo, Ferreira da Rocha Sant'Ana, Luciana, and Eloiza Priore, Silvia
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Impedancia eléctrica ,Electric impedance ,Adolescents ,Body composition ,Adolescentes ,Composición corporal - Abstract
Introduction: An accurate estimate of body composition is important in assessing and monitoring the nutritional status of adolescents. Objectives: To compare the accuracy of 2 electrical bioimpedance devices with that of dual-energy X-ray absorptiometry (DXA) to predict body fat in Brazilian adolescents. Methods: We evaluated 500 adolescents aged between 10 and 19 years, stratified by sex and divided into overweight and non-overweight groups. The percentage of body fat (%BF) was estimated using 2 types of electrical bioimpedance devices: BIA1 (horizontal tetrapolar bioimpedance equipment) and BIA2 (vertical 8-electrode bioimpedance equipment), as well as by DXA. A Bland-Altman plot was used to calculate the total errors and standard errors of estimate. Results: Considering BMI for age, 19.4% were overweight and 47.4% as assessed by %BF of DXA were overweight. The %BF estimated by BIA2 correlated well (p < 0.05) with the %BF predicted by DXA, and only the total errors for BIA2 in the overweight group were acceptable (≤2.5%). The standard errors of estimate was
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- 2014
31. Prebiotics prevent the appearance of aberrant crypt foci (ACF) in the colon of Balb/C mice for increasing the gene expression of p16 protein
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Freitas Gomides, Antônio Frederico, Paula, Sérgio Oliveira de, Gonçalves, Reggiani Vilela, Oliveira, Leandro Licursi de, Luces Fortes Ferreira, Célia Lúcia de, Comastri, Débora Silva, and Gouveia Peluzio, Maria do Carmo
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Prebióticos ,Prebiotics ,Prevención colon ,Prevention colon ,Cripta aberrante ,Aberrant crypt ,P16 protein ,Proteína P16 - Abstract
Background: Studies have shown fibers to be effective in reducing the appearance of aberrant crypt foci (ACF) in rodents. Objective: The goal of this study was to investigate the preventive effects of fructooligosaccharide (FOS) and inulin prebiotics on the appearance of ACF in mice. Materials and Methods: The techniques used were: RT-PCR to evaluate the gene expression of p16, p21, p54, cyclin D1 and cyclin E in the distal colon; the quantification of Number of aberrant crypt foci (ACF) and measurement of catalase activity in the liver and distal colon. The animals were divided into five treatments (n=8); C-: AIN93M diet without fibers + DMH (1,2-dimethylhydrazine); INL: AIN93M diet with inulin; INLCA: AIN93M diet with inulin + DMH; FOS: AIN93M diet with FOS; FOSCA: AIN93M diet with FOS + DMH, during 15 weeks. Results: Inulin prevented the appearance of ACF in the proximal, middle and distal colon, compared to the control without fibers. In the middle and distal colon, FOS was also effective in preventing the incidence of ACF. This effectiveness may be attributed to the increased gene expression of p16 following FOS treatment. Both prebiotics also decreased catalase activity in the distal colon, thus suggesting an antioxidant effect. Conclusion: These results suggesting an antioxidant effect prebiotics that may be attributed to the increased gene expression of p16. Introducción: Existen estudios que demuestran la eficacia de fibras para reducir la aparición de focos de cripta aberrantes (FCA) en roedores. Objetivo: El objetivo de este estudio consistió en investigar los efectos preventivos de los fructooligosacáridos (FOS) y el prebiótico inulina sobre la aparición de FCA en ratones. Materiales y métodos: Las técnicas empleadas fueron: RT-PCR para evaluar la expresión gènica de p16, p21, p54, ciclina D1 y ciclina E en el colon distal; la cuantificación del Número de FCA y la medición de la actividad de la catalasa en el hígado y el colon distal. Los animales fueron divididos en cinco tratamientos (n=8); C-: dieta AIN93M sin fibra + DMH (1.2-dimetilhidrazina); INL: dieta AIN93M con inulina; INLCA: dieta AIN93M con inulina + DMH; FOS: dieta ANIN93M con FOS; FOSCA: dieta AIN93M con FOS + DMH, durante 15 semanas. Resultados: La inulina previno la aparición de FCA en el colon proximal, medio y distal, comparado con el control sin fibras. En el colon medio y distal, FOS también fue efectiva para prevenir la incidencia de FCA. Esta efectividad podría ser atribuida al aumento de la expresión génica de p16 tras el tratamiento con FOS. Ambos prebióticos también disminuyeron la actividad de la catalasa en el colon distal, lo que sugiere un efecto antioxidante. Conclusión: Estos resultados sugieren un efecto antioxidante de los prebióticos que podría atribuirse a un aumento de la expresión génica de p16.
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- 2014
32. Evaluation of the subchronic toxicity of kefir by oral administration in Wistar rats
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Diniz Rosa, Damiana, Gouveia Peluzio, Maria do Carmo, Pérez Bueno, Tania, Vega Cañizares, Ernesto, Sánchez Miranda, Lilian, Mancebo Dorbignyi, Betty, Chong Dubí, Dainé, Espinosa Castaño, Ivette, Marcin Grześkowiak, Łukasz, and Fortes Ferreira, Célia Lucia de Luces
- Subjects
Kefir ,Kéfir ,Análisis histológico ,Toxicity ,Bacterial translocation ,Histological analysis ,Translocación bacteriana ,Safety ,Toxicidad ,Seguridad - Abstract
Introduction: Kefir is obtained by fermentation of milk with complex microbial populations present in kefir grains. Several health-promoting benefits have been attributed to kefir consumption. Objective: The objective of this work was to conduct a subchronic toxicity study, offering the rats normal or high-doses of kefir and evaluating growth, hematology and blood chemistry, as well as assessing bacterial translocation and the integrity of the intestinal mucosa of animals. Methods: Wistar rats were randomly divided into three groups (n = 6/group): control group received 0.7 mL of water, kefir group received 0.7 mL/day of kefir, (normodose), and Hkefir group received 3.5 mL/day of kefir (fivefold higher dose). Feeding was carried out by gavage. The animals were housed in individual cages and maintained under standard conditions for 4 weeks. Results: The normodose and high-dose of kefir supplementation did not harm the animals since growth, hematology and blood chemistry in rats, as well as the potential pathogenicity in tissues were within normal limits, demonstrating that consumption of normodose and highdose of kefir are safe. In addition, administration of the normodose of kefir reduced cholesterol levels and improved the intestinal mucosa of the rats. Conclusion: These results demonstrate that the consumption of kefir is safe. Importantly, while damages are not seen for the high-dose, the normodose consumption is recommended due to the pronounced beneficial effects, as safety is concerned. Introducción: El kéfir es obtenido por fermentación de la leche con una población microbiana compleja presente en sus granos. Al consumo de kéfir se le atribuyen múltiples efectos beneficiosos sobre la salud. Objetivo: Evaluar la toxicidad subcrónica del kéfir en ratas Wistar, administrado por vía oral en dosis normal (normodosis) y sobredosis. Se evaluaron además, los parámetros de peso corporal, hematología, química sanguínea, translocación bacteriana e integridad de la mucosa intestinal. Métodos: Se conformaron tres grupos de seis animales de manera aleatoria: grupo control, recibió 0,7 mL de agua; grupo kéfir recibió 0,7 mL/día de kéfir (normodosis) y grupo Hkéfir recibió 3,5 mL/día de kéfir (dosis cinco veces superior). La administración se llevó a cabo mediante sonda. Los animales se alojaron individualmente, y se mantuvieron bajo las mismas condiciones de manejo y alimentación durante 4 semanas. Resultados: La administración de kéfir en dosis normal y sobredosis no afectó los parámetros evaluados en los animales, el peso corporal, indicadores hematológicos, de química sanguínea, y la patogenicidad potencial en los tejidos se encontraron dentro de límites normales, lo que demostró que el consumo de kéfir en dosis normal y sobredosis es seguro. Además, se evidenció que la administración de normodosis de kéfir redujo los niveles de colesterol y mejoró la mucosa intestinal de las ratas. Conclusión: Se demostró que el consumo de kéfir es seguro. Destacar que, la administración de sobredosis no evidenció daños, no obstante, se recomienda el consumo de normodosis, debido a los marcados efectos beneficiosos y de seguridad.
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- 2014
33. Intestinal permeability measurements: general aspects and possible pitfalls
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Fiche Salles Teixeira,Tatiana, Boroni Moreira,Ana Paula, Silva Souza,Nilian Carla, Frias,Rafael, and Gouveia Peluzio,Maria do Carmo
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Lactulosa ,Barrera intestinal ,Intestinal permeability ,Lactulose ,Manitol ,Fisiología intestinal ,Permeability ,Tight Junctions ,lcsh:Nutritional diseases. Deficiency diseases ,Intestinal Absorption ,Gut barrier ,Permeabilidad intestinal ,Humans ,Mannitol ,lcsh:RC620-627 - Abstract
Disturbances of the gut barrier function have been related to a variety of diseases, including intestinal and extra-intestinal diseases. The intestinal permeability tests are considered useful tools for evaluating disease severity and to follow-up patients after a therapeutic intervention and indirectly assess barrier function.The aims of this review were to highlight the possible factors underlying higher intestinal permeability and the clinical conditions that have been associated with this in different age range; and also provide some insight into methodological aspects.Abnormal regulation of tight junction function is the main cause of altered intestinal barrier. The impaired barrier function results in higher permeation rates of administered probes through the intestinal mucosa. Lactulose and mannitol are one of the most commonly used probes. The innocuousness and easiness of intestinal permeability tests can be explored to expand the knowledge about the clinical situations in which intestinal barrier dysfunction can be an important feature. Many factors may influence the results of the test. Researchers and healthcare professionals should try to circumvent the possible pitfalls of the intestinal permeability tests to produce consistent evidences. The use of others markers of intestinal physiology may also contribute to understand the role of barrier function in different diseases.Introducción: Alteraciones funcionales de la barrera intestinal se han relacionado con una variedad de enfermedades intestinales y también con enfermedades no intestinales. Las pruebas de permeabilidad intestinal son consideradas herramientas útiles para evaluar la gravedad de la enfermedad para el posterior seguimiento de los pacientes después de una intervención terapéutica. Objetivo: El objeto de esta revisión ha sido destacar los posibles factores que pueden estar asociados a una mayor permeabilidad intestinal y revisar condiciones clínicas que han sido asociadas en individuos de diferentes edades. También revisar ciertos aspectos metodológicos de las pruebas de permeabilidad intestinal. Resultados y discusión: Las uniones estrechas entre los enterocitos son las principales estructuras encargadas de la regulación de la barrera intestinal. Una alteración de éstas, resulta en una deficiencia en la permeabilidad intestinal y una mayor penetración de las sustancias marcadoras de permeabilidad intestinal. La lactulosa y el manitol son las sustancias marcadoras más utilizadas. La inocuidad y facilidad de los test de permeabilidad han sido de ayuda para explorar y ampliar el conocimiento de muchas condiciones clínicas en las que la disfunción de la barrera intestinal ha sido un sello distintivo. Muchos factores pueden influir en los resultados de los test de permeabilidad. Sin embargo, los investigadores y los clínicos han de tratar de eludir los posibles inconvenientes de las pruebas de permeabilidad intestinal para poder producir evidencias más consistentes. El uso de otras sustancias marcadoras de la fisiología intestinal también puede contribuir a comprender mejor el papel de la barrera intestinal en diferentes enfermedades.
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- 2014
34. Intestinal permeability measurements: general aspects and possible pitfalls
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Fiche Salles Teixeira, Tatiana, Boroni Moreira, Ana Paula, Silva Souza, Nilian Carla, Frias, Rafael, and Gouveia Peluzio, Maria do Carmo
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Lactulosa ,Gut barrier ,Permeabilidad intestinal ,Barrera intestinal ,Mannitol ,Intestinal permeability ,Lactulose ,Manitol ,Fisiología intestinal - Abstract
Introduction: Disturbances of the gut barrier function have been related to a variety of diseases, including intestinal and extra-intestinal diseases. The intestinal permeability tests are considered useful tools for evaluating disease severity and to follow-up patients after a therapeutic intervention and indirectly assess barrier function. Objective: The aims of this review were to highlight the possible factors underlying higher intestinal permeability and the clinical conditions that have been associated with this in different age range; and also provide some insight into methodological aspects. Results and discussion: Abnormal regulation of tight junction function is the main cause of altered intestinal barrier. The impaired barrier function results in higher permeation rates of administered probes through the intestinal mucosa. Lactulose and mannitol are one of the most commonly used probes. The innocuousness and easiness of intestinal permeability tests can be explored to expand the knowledge about the clinical situations in which intestinal barrier dysfunction can be an important feature. Many factors may influence the results of the test. Researchers and healthcare professionals should try to circumvent the possible pitfalls of the intestinal permeability tests to produce consistent evidences. The use of others markers of intestinal physiology may also contribute to understand the role of barrier function in different diseases. Introducción: Alteraciones funcionales de la barrera intestinal se han relacionado con una variedad de enfermedades intestinales y también con enfermedades no intestinales. Las pruebas de permeabilidad intestinal son consideradas herramientas útiles para evaluar la gravedad de la enfermedad para el posterior seguimiento de los pacientes después de una intervención terapéutica. Objetivo: El objeto de esta revisión ha sido destacar los posibles factores que pueden estar asociados a una mayor permeabilidad intestinal y revisar condiciones clínicas que han sido asociadas en individuos de diferentes edades. También revisar ciertos aspectos metodológicos de las pruebas de permeabilidad intestinal. Resultados y discusión: Las uniones estrechas entre los enterocitos son las principales estructuras encargadas de la regulación de la barrera intestinal. Una alteración de éstas, resulta en una deficiencia en la permeabilidad intestinal y una mayor penetración de las sustancias marcadoras de permeabilidad intestinal. La lactulosa y el manitol son las sustancias marcadoras más utilizadas. La inocuidad y facilidad de los test de permeabilidad han sido de ayuda para explorar y ampliar el conocimiento de muchas condiciones clínicas en las que la disfunción de la barrera intestinal ha sido un sello distintivo. Muchos factores pueden influir en los resultados de los test de permeabilidad. Sin embargo, los investigadores y los clínicos han de tratar de eludir los posibles inconvenientes de las pruebas de permeabilidad intestinal para poder producir evidencias más consistentes. El uso de otras sustancias marcadoras de la fisiología intestinal también puede contribuir a comprender mejor el papel de la barrera intestinal en diferentes enfermedades.
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- 2014
35. Prediction of body fat in adolescents: comparison of two electric bioimpedance devices with dual-energy X-ray absorptiometry
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Rodrigues de Faria,Eliane, Rocha de Faria,Franciane, Siqueira Santos Gonçalves,Vivian, Castro Franceschini,Sylvia do Carmo, Gouveia Peluzio,Maria do Carmo, Ferreira da Rocha Sant'Ana,Luciana, and Eloiza Priore,Silvia
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Electric impedance ,Adolescents ,Body composition - Abstract
Introduction: An accurate estimate of body composition is important in assessing and monitoring the nutritional status of adolescents. Objectives: To compare the accuracy of 2 electrical bioimpedance devices with that of dual-energy X-ray absorptiometry (DXA) to predict body fat in Brazilian adolescents. Methods: We evaluated 500 adolescents aged between 10 and 19 years, stratified by sex and divided into overweight and non-overweight groups. The percentage of body fat (%BF) was estimated using 2 types of electrical bioimpedance devices: BIA1 (horizontal tetrapolar bioimpedance equipment) and BIA2 (vertical 8-electrode bioimpedance equipment), as well as by DXA. A Bland-Altman plot was used to calculate the total errors and standard errors of estimate. Results: Considering BMI for age, 19.4% were overweight and 47.4% as assessed by %BF of DXA were overweight. The %BF estimated by BIA2 correlated well (p < 0.05) with the %BF predicted by DXA, and only the total errors for BIA2 in the overweight group were acceptable (≤2.5%). The standard errors of estimate was
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- 2014
36. Biological effects of anthocyanins on the atherosclerotic process
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Cardoso, Luciana Marques, Viana Leite, Joâo Paulo, and Gouveia Peluzio, Maria do Carmo
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Anthocyanins ,antiinflamator ,antioxidants ,Aterosclerose ,Antiinflamatório ,fungi ,Antocianinas ,food and beverages ,Antioxidante ,atherosclerosis - Abstract
As antocianinas são metabólitos secundários biossintetizados por plantas e pertencentes ao grupo dos flavonóides. Pesquisas indicam que as antocianinas podem aumentar a resistência da LDL à oxidação, comparado a outros compostos com alto poder antioxidante, como o ácido L-ascórbico, e reduzir fatores pró-inflamatórios, como citocinas, quimiocinas, moléculas de adesão e metaloproteinases. Como a inflamação e a oxidação são processos característicos da aterosclerose, tem se investigado o efeito das antocianinas no processo aterosclerótico e há evidências que estes compostos podem diminuir o desenvolvimento e a progressão das lesões ateroscleróticas. Anthocyanins are secondary metabolites biosynthesized by plants and belonging to the group of flavonoids. Research indicates that anthocyanins can increase resistance of LDL to oxidation, compared to other compounds with high antioxidant properties, such as L-ascorbic acid, and reduce pro-inflammatory factors such as cytokines, chemokines, adhesion molecules and metalloproteinases. As inflammation and oxidation processes are characteristic of atherosclerosis, has investigated the effect of anthocyanins in the atherosclerotic process and there is evidence that these compounds can reduce the development and progression of atherosclerotic lesions.
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- 2011
37. Efeitos biológicos das antocianinas no processo aterosclerótico
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Marques Cardoso, Luciana, Viana Leite, João Paulo, and Gouveia Peluzio, Maria do Carmo
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54 Química y ciencias afines / Chemistry ,fungi ,food and beverages ,5 Ciencias naturales y matemáticas / Science ,anthocyanins - Abstract
As antocianinas são metabólitos secundários biossintetizados por plantas e perten- centes ao grupo dos flavonóides. Pesquisas indicam que as antocianinas podem aumentar a resistência da LDL à oxidação, comparado a outros compostos com alto poder antioxidante, como o ácido L-ascórbico, e reduzir fatores pró-inflamatórios, como citocinas, quimiocinas, moléculas de adesão e metaloproteinases. Como a inflamação e a oxidação são processos característicos da aterosclerose, tem se investi- gado o efeito das antocianinas no processo aterosclerótico e há evidências que estes compostos podem diminuir o desenvolvimento e a progressão das lesões ateroscle- róticas. Anthocyanins are secondary metabolites biosynthesized by plants and belonging to the group of flavonoids. Research indicates that anthocyanins can increase resis- tance of LDL to oxidation, compared to other compounds with high antioxidant properties, such as L-ascorbic acid, and reduce pro-inflammatory factors such as cytokines, chemokines, adhesion molecules and metalloproteinases. As inflamma- tion and oxidation processes are characteristic of atherosclerosis, has investigated the effect of anthocyanins in the atherosclerotic process and there is evidence that these compounds can reduce the development and progression of atherosclerotic lesions.
- Published
- 2011
38. Prevalência e fatores associados à anemia e deficiência de ferro em crianças de 18 a 24 meses
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Michele Pereira, Netto, Silvia Eloiza, Priore, Pinheiro Sant'Ana, Helena Maria, Gouveia Peluzio, Maria do Carmo, Sabarense, Céphora Maria, Góes da Silva, Danielle, and Castro Franceschini, Sylvia do Carmo
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nutrição infantil ,iron deficiency ,iron ,infant nutrition ,deficiência de ferro ,lactentes ,Anemia ,ferro ,infant - Abstract
Foi realizado um estudo transversal com 101 lactentes de 18 a 24 meses atendidos em serviços públicos de saúde da cidade de Viçosa, MG, Brasil. Objetivou-se verificar a prevalência e os fatores associados à anemia e deficiência de ferro entre lactentes. As informações foram obtidas através de entrevista aos pais ou responsáveis pelas crianças, realizadas nos domicílios. Foram feitas análises da hemoglobina e ferritina, por um contador automático e pelo método de doseamento imunométrico, respectivamente. As amostras de fezes foram analisadas pelos métodos de Hoffman, Faust e Ritchie. Caracterizou-se anemia através da concentração de hemoglobina e a deficiência de ferro através da ferritina. Na avaliação da prática alimentar utilizou-se o recordatório de 24 horas. Foram feitas análises de regressão linear e logística para avaliar as variáveis associadas à hemoglobina e a deficiência de ferro, respectivamente. As prevalências de anemia, deficiência de ferro e parasitoses intestinais foram de 30,1; 38,4 e 21%, respectivamente. O número de moradores na casa, idade de introdução de sucos e/ou frutas, escolaridade materna e tempo de aleitamento materno total associaram-se aos níveis plasmáticos de hemoglobina. Para a deficiência de ferro as variáveis associadas foram consumo de leite próximo das refeições e número de moradores na casa. A transversal study was carried out with 101 18-to 24-month old infants, attended at public health services in Viçosa, MG, Brazil, The objective of this study was to verify the prevalence and factors associated to anemia and iron deficiency among infants. Data were obtained by interviews of the infants’ parents or guardians at their households. Hemoglobin and ferritin analyses were peformed using an automatic counter and the immunometric dosage method, respectively. Feces samples were analyzed by the Hoffman, Faust and Ritchie methods. Anemia was characterized by hemoglobin concentration and iron deficiency by ferritin. For dietary practice, the 24-hour recall was used. Linear regression and logistics analyses were conducted to evaluate the variables associated to hemoglobin and iron deficiency, respectively. Anemia, iron deficiency and intestinal parasite prevalences were 30.1; 38.4, and 21%, respectively. The number of household members, age infants were introduced to juices/or fruit, mother’s level of instruction, and total breastfeeding period were associated to the levels of hemoglobin plasma. The associated variables for iron deficiency were milk consumption near meals and number of household members.
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- 2006
39. Intestinal Microbiota and Probiotics in Celiac Disease
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de Sousa Moraes, Luís Fernando, primary, Grzeskowiak, Lukasz Marcin, additional, de Sales Teixeira, Tatiana Fiche, additional, and Gouveia Peluzio, Maria do Carmo, additional
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- 2014
- Full Text
- View/download PDF
40. Biological effects of anthocyanins on the atherosclerotic process
- Author
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Marques Cardoso, Luciana, Viana Leite, João Paulo, Gouveia Peluzio, Maria do Carmo, Marques Cardoso, Luciana, Viana Leite, João Paulo, and Gouveia Peluzio, Maria do Carmo
- Abstract
Anthocyanins are secondary metabolites biosynthesized by plants and belonging to the group of flavonoids. Research indicates that anthocyanins can increase resis- tance of LDL to oxidation, compared to other compounds with high antioxidant properties, such as L-ascorbic acid, and reduce pro-inflammatory factors such as cytokines, chemokines, adhesion molecules and metalloproteinases. As inflamma- tion and oxidation processes are characteristic of atherosclerosis, has investigated the effect of anthocyanins in the atherosclerotic process and there is evidence that these compounds can reduce the development and progression of atherosclerotic lesions., As antocianinas são metabólitos secundários biossintetizados por plantas e perten- centes ao grupo dos flavonóides. Pesquisas indicam que as antocianinas podem aumentar a resistência da LDL à oxidação, comparado a outros compostos com alto poder antioxidante, como o ácido L-ascórbico, e reduzir fatores pró-inflamatórios, como citocinas, quimiocinas, moléculas de adesão e metaloproteinases. Como a inflamação e a oxidação são processos característicos da aterosclerose, tem se investi- gado o efeito das antocianinas no processo aterosclerótico e há evidências que estes compostos podem diminuir o desenvolvimento e a progressão das lesões ateroscle- róticas.
- Published
- 2011
41. B vitamins related to homocysteine metabolism in adults celiac disease patients: a cross-sectional study.
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Xavier Valente, Flávia, do Nascimento Campos, Tatiana, de Sousa Moraes, Luís Fernando, Miranda Hermsdorff, Helen Hermana, de Morais Cardoso, Leandro, Pinheiro-Sant'Ana, Helena Maria, Barros Gilberti, Flávio Augusto, Gouveia Peluzio, Maria do Carmo, Valente, Flávia Xavier, Campos, Tatiana do Nascimento, Moraes, Luís Fernando de Sousa, Hermsdorff, Helen Hermana Miranda, Cardoso, Leandro de Morais, Gilberti, Flávio Augusto Barros, and Peluzio, Maria do Carmo Gouveia
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CELIAC disease ,FOLIC acid ,GLUTEN-free diet ,NUTRITIONAL requirements ,VITAMIN B complex ,VITAMIN B12 ,VITAMIN B6 ,HOMOCYSTEINE ,CROSS-sectional method ,FOOD diaries ,NUTRITIONAL status - Abstract
Background: The only treatment for celiac disease is the gluten-free diet. Few studies have assessed the nutritional adequacy of this diet, especially of B vitamins related to homocysteine metabolism. The aim of this study was to assess the nutritional status and serum concentrations of B vitamins involved in homocysteine metabolism, and to determine whether the dietary intake of these vitamins are meeting Dietary Reference Intakes in celiac patients.Methods: A cross-sectional study enrolled a total of 20 celiac patients (36.3 ± 13.7 years old; 65% women), following strict gluten-free diet (GFD) and 39 healthy controls matched by sex and age. The dietary intake was assessed by 3-day food records, and serum concentrations of homocysteine and vitamins B6, B12, and folate were determined after overnight fasting. Comparisons between the two groups were performed by Student's t test or Mann-Whitney U-test, for continuous variables. Pearson's chi-square test or Fisher's exact test was used for categorical variables. An alpha level of 5% were considered significant.Results: Celiac patients had lower serum folate concentrations (7.7 ± 3.5 ng/mL, P < 0.05) than controls. All celiac patients had folate intake below the Estimated Average Requirement (EAR) (130.8 ± 53.6 μg/d). However, only a small proportion of celiac patients had hyperhomocysteinemia.Conclusions: Celiac patients treated with GFD presented inadequacy of dietary folate intake and low-serum concentrations of folate, suggesting that more attention should be given to the quality of the nutrients offered by the GFD, as it constitutes a lifelong treatment. [ABSTRACT FROM AUTHOR]- Published
- 2015
- Full Text
- View/download PDF
42. Inflammatory markers in relation to body composition, physical activity and assessment of nutritional status of the adolescents.
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Neves Miranda, Valter Paulo, Gouveia Peluzio, Maria do Carmo, Rodrigues de Faria, Eliane, Castro Franceschini, Sylvia do Carmo, and Priore, Silvia Eloiza
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- *
ADOLESCENT nutrition , *INFLAMMATION , *PHYSICAL activity , *NUTRITIONAL status , *NUTRITIONAL assessment , *HUMAN body composition - Abstract
Introduction: The evaluation of inflammatory markers during adolescence can monitor different stages and manifestation of chronic diseases in adulthood. The control of the subclinical inflammation process through changes in lifestyle, especially in the practice of physical activity and dietary education can mitigate the effects of risk factors that trigger the process of atherosclerosis. Objective: To do a critical review regarding inflammatory markers as a risk factor of cardiovascular disease in relation to body composition, physical activity and assessment of nutritional status of adolescents. Methods: A literature review was performed in the following electronic databases: PUBMED, SCIELO and CONCHRANE COLLECTION. The following associated terms were used “inflammation AND cardiovascular diseases AND nutritional status OR body composition OR physical activity". There were topics created for the discussion of subjects: obesity and risk factors for cardiovascular disease during adolescence; expression of inflammatory markers in adolescence; development of cardiovascular disease with inflammatory markers, and finally, inflammatory markers, physical activity and nutritional evaluation. Results: It was observed that the inflammatory markers may manifest in adolescence and be related to risk factors for cardiovascular diseases. Physical activity and nutritional evaluation featured as non-pharmacological measures to control the incidence of inflammatory markers and cardiovascular risk factor. Conclusions: Intervention studies may clarify how the adoption of a more proper lifestyle can influence the inflammatory process. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
43. Anthropometric indices to identify metabolic syndrome and hypertriglyceridemic waist phenotype: a comparison between the three stages of adolescence.
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Pereira, Patrícia Feliciano, de Faria, Franciane Rocha, de Faria, Eliane Rodrigues, Hermsdorff, Helen Hermana Miranda, Gouveia Peluzio, Maria do Carmo, Castro Franceschini, Sylvia do Carmo, and Priore, Silvia Eloiza
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ANTHROPOMETRY research ,METABOLIC syndrome diagnosis ,OBESITY risk factors ,ADOLESCENT obesity - Abstract
Copyright of Revista Paulista de Pediatria is the property of Assocoacao de Pediatria de Sao Paulo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
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44. EFEITO DA DIETA HIPERLIPÍDICA E DO TREINAMENTO AERÓBICO NA ATEROSCLEROSE EM CAMUNDONGOS apoE-/-.
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Toledo Fernandes, Silvio Anderson, Natali, Antônio José, Pinto da Matta, Sérgio Luis, Gonzaga Teodoro, Bruno, Caldoncelli Franco, Frederico Souzalima, Camaroti Laterza, Mateus, and Gouveia Peluzio, Maria do Carmo
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ANAEROBIC training ,LABORATORY mice ,ATHEROSCLEROSIS ,DIET ,CARDIOVASCULAR diseases ,BODY weight ,LIPID metabolism - Abstract
The article presents a study which investigates the effects of hyperlipidic diet and aerobic training on mice with atherosclerosis. The study assess the body weight (BW), food intake (FI) , and relative liver weight (RLW) in 26 rats divided into groups/diet. The study concluded that disturbances in the lipid metabolism and cardiovascular disease can be triggered by high fat diet but may decrease atherosclerosis when associated with activity.
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- 2013
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45. Body Fat Equations and Electrical Bioimpedance Values in Prediction of Cardiovascular Risk Factors in Eutrophic and Overweight Adolescents.
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Faria, Franciane Rocha, Faria, Eliane Rodrigues, Cecon, Roberta Stofeles, Barbosa Jùnior,, Djalma Adão, Castro Franceschini, Sylvia do Carmo, Gouveia Peluzio, Maria do Carmo, Ribeiro, Andréia Queiroz, Lira, Pedro Israel Cabral, Cecon, Paulo Roberto, and Priore, Silvia Eloiza
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BODY composition ,CARDIOVASCULAR system physiology ,EUTROPHICATION ,OVERWEIGHT persons ,REGRESSION analysis ,HOMEOSTASIS - Abstract
The aim of this study was to analyze body fat anthropometric equations and electrical bioimpedance analysis (BIA) in the prediction of cardiovascular risk factors in eutrophic and overweight adolescents. 210 adolescents were divided into eutrophic group (G1) and overweight group (G2).The percentage of body fat (% BF) was estimated using 10 body fat anthropometric equations and 2 BIA. We measured lipid profiles, uric acid, insulin, fasting glucose, homeostasis model assessment-insulin resistance (HOMA-IR), and blood pressure. We found that 76.7% of the adolescents exhibited inadequacy of at least one biochemical parameter or clinical cardiovascular risk. Higher values of triglycerides (TG) (P = 0.001), insulin, and HOMA-IR (P < 0.001) were observed in the G2 adolescents. Inmultivariate linear regression analysis, the % BF fromequation (5) was associated with TG, diastolic blood pressure, and insulin in G1. Among the G2 adolescents, the % BF estimated by (5) and (9) was associated with LDL, TG, insulin, and the HOMA-IR. Body fat anthropometric equations were associated with cardiovascular risk factors and should be used to assess the nutritional status of adolescents. In this study, equation (5) was associated with a higher number of cardiovascular risk factors independent of the nutritional status of adolescents. [ABSTRACT FROM AUTHOR]
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- 2013
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46. A Influência da Intensidade do Exercício Físico Aeróbio no Processo Aterosclerótico.
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Teodoro, Bruno Gonzaga, Natali, Antônio José, Toledo Fernandes, Sílvio Anderson, and Gouveia Peluzio, Maria do Carmo
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- 2010
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47. Difference in fatty acids composition of breast adipose tissue in women with breast cancer and benign breast disease.
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Dias, Mariana De Moura, Pena, Geórgia Das Graças, Mendes, Maria Carolina Santos, Neves, Cristiane Vilas Boas, Hermsdorff, Helen Hermana Miranda, Freitas, Renata Nascimento, Peluzio, Maria do Carmo Gouveia, Lopes da Conceição, Lisiane, de Moura e. Dias, Mariana, Pessoa, Milene Cristine, Santos Mendes, Maria Carolina, Miranda Hermsdorff, Helen Hermana, Gouveia Peluzio, Maria do Carmo, das Graças Pena, Geórgia, Vilas Boas Neves, Cristiane, Nascimento de Freitas, Renata, and Conceição, Lisiane Lopes da
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FATTY acids , *ADIPOSE tissues , *BREAST cancer , *ANTHROPOMETRY , *SATURATED fatty acids , *MONOUNSATURATED fatty acids - Abstract
Introduction: Breast cancer is the second most common cancer in the world, and the most frequent cancer among women. Moreover, there are factors that influence the risk for breast cancer including the age, genetic and endocrine factors, and lifestyle.Objectives: To evaluate the consumption of fatty acids; compare the fatty acids composition in the breast adipose tissue of women with breast cancer and benign breast disease as well as potential risk factors; and describe the genotypic frequency of the Pro12Ala PPARγ polymorphism.Material and Methods: A hospital-based case-control study was conducted including incident cases (n= 38 breast cancer; n= 75 benign breast disease; n= 166 control). Lifestyle features, socioeconomic issues, dietary intake, anthropometry, and blood and tissue data were assessed.Results: No differences were observed for fatty acids intake. Interestingly, lauric acid (p = 0.001), myristic acid (p = 0.036), stearic acid (p = 0.031), and total saturated fatty acids (SFAs) (p = 0.048) had lower concentrations in BC than in BBD women, while palmitoleic acid (p = 0.022), erucic acid (p = 0.002), total monounsaturated fatty acids (MUFAs) (p = 0.039) and oleic acid/stearic acid ratio (p = 0.015) increased. There was no significant association between PPARγ polymorphism and studied groups (p = 0.977). The age at first full pregnancy (p = 0.004) was significantly associated with the development BC, whereas BMI (p = 0.005); percentage of body fat (p = 0.024); physical activity (p = 0.036); and age at menarche (p = 0.008), at first full pregnancy (p < 0.001), and of first mammogram (p = 0.018) were significantly associated with the development of BBD.Conclusion: The results suggest a different fatty acids composition of breast adipose tissue, a biomarker of long-term dietary intake, particularly for SFAs, MUFA and 18: 1 n-9/18: 00 ratio. Our findings also show that are differences in the factors related to the development of BC and BBC. [ABSTRACT FROM AUTHOR]- Published
- 2016
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48. Lifestyle and vitamin D dosage in women with breast cancer.
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Dias, Manoela Maciel Dos Santos, Queiroz, Andréia Ribeiro, Suhett, Lara Gomes, Freitas, Renata Nascimento, De Paula, Sérgio Oliveira, Peluzio, Maria do Carmo Gouveia, dos Santos Dias, Manoela Maciel, Pessoa, Milene Cristine, Ribeiro Queiroz, Andréia, Gomes Suhett, Lara, Gouveia Peluzio, Maria do Carmo, Nogueira Oliveira-Sediyama, Catarina Maria, Nascimento Freitas, Renata, Oliveira de Paula, Sérgio, and Oliveira Sediyama, Catarina Maria
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VITAMIN D , *BREAST cancer diagnosis , *MENOPAUSE , *PHYSICAL activity , *LOGISTIC regression analysis , *BREAST tumors , *DIETARY calcium , *VITAMINS , *SOCIOECONOMIC factors , *LIFESTYLES , *CASE-control method - Abstract
Introduction: The prevention strategy of breast cancer is still the key factor for early diagnosis and the most effective method for tracking the disease.Objective: This study aimed to evaluate the association vitamin D level with breast cancer in women.Methods: This hospital case-control study was conducted with 181 women with breast cancer and 197 healthy controls. Vitamin D status, calcium, phosphorus and PTH serum dosage and data collection related to lifestyle and patient's history, besides anthropometric measurements were performed. Univariate analysis (Chi-square and raw odds ratio) and multivariate analysis were performed through multivariate logistic regression.Results: This study shows a higher value of vitamin D in health controls (26.9 mg/dL) than in breast cancer women (24.8 mg/dL). Higher numbers of women with sufficient vitamin D status (34.85%) were found in control group than cancer group. Using the multiple logistic regression model, the family history of breast cancer (OR 36.37, 95%CI 4.75-278.50) and menopause (OR 5.17, 95% CI 2.72-9.80) had a direct association with breast cancer, while the level of vitamin D (OR 0.95, 95%CI 0.91-0.99) and moderate physical activity (OR 0.31, 95%CI 0.10-0.93) maintained the inverse associations with the disease.Conclusion: Vitamin D status and the practice of moderate physical activity were considered protective factors for breast cancer. However, menopause and family history of breast cancer were considered a risk factor for breast cancer. [ABSTRACT FROM AUTHOR]- Published
- 2016
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49. CHEMICAL COMPOSITION, CHARACTERIZATION OF ANTHOCYANINS AND ANTIOXIDANT POTENTIAL OF EUTERPE EDULIS FRUITS: APPLICABILITY ON GENETIC DYSLIPIDEMIA AND HEPATIC STEATOSIS IN MICE.
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Cardoso, Luciana Marques, Novaes, Rômulo Dias, de Castro, Cynthia Aparecida, Novello, Alexandre Azevedo, Gonçalves, Reggiani Vilela, Ricci-Silva, Maria Esther, de Oliveira Ramos, Humberto Josué, do Carmo Gouveia Peluzio, Maria, Viana Leite, João Paulo, Marques Cardoso, Luciana, Dias Novaes, Rômulo, Aparecida de Castro, Cynthia, Azevedo Novello, Alexandre, Vilela Gonçalves, Reggiani, and Gouveia Peluzio, Maria do Carmo
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EUTERPE edulis , *ANTHOCYANINS , *ANTIOXIDANTS , *DYSLIPIDEMIA , *FATTY liver - Abstract
Unlabelled: The significance of polyphenol intake for the prevention of chronic diseases is controversial.Objective: this study investigated the chemical composition and antioxidant potential of an anthocyanin-rich extract from Euterpe edulis fruits (LPEF) and its effects on liver steatosis in dyslipidemic apoE-/- knockout mice.Materials and Methods: mice were divided into G1 (C57BL/6) standard diet; G2 (apoE-/-) standard diet, G3 (apoE-/-) 2% LPEF, G4 (apoE-/-) 6% LPEF, G5 (apoE-/-) 10% LPEF, G6 (apoE-/-) 2% α-tocopherol acetate. After 75 days of treatment, the animals were euthanized. The LPEF contained a high level of monomeric anthocyanins (301.4 mg/100g) and marked antioxidant activity.Results: Catalase activity was reduced in G3, G4, G5 and G6 compared to G2. Superoxide dismutase was reduced only in G4. The animals in G4, G5, and G6 showed low HDL and triglycerides levels compared to G2. The proportion of lipid droplets in liver tissue was reduced in G4 and G5 compared to G2, G3, and G6.Conclusion: The results indicated that E. edulis pulp is rich in anthocyanins and the LPEF dietary consumption can reduce the severity of liver steatosis in apoE-/- mice, an effect that is potentially mediated by the antioxidant activity of this extract and modulation of triglyceride serum levels. [ABSTRACT FROM AUTHOR]- Published
- 2015
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50. Mechanisms used by inulin-type fructans to improve the lipid profile.
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Aparecida dos Reis, Sandra, Lopes da Conceição, Lisiane, Diniz Rosa, Damiana, Maciel dos Santos Dias, Manoela, and Gouveia Peluzio, Maria do Carmo
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INULIN , *FRUCTANS , *DYSLIPIDEMIA , *CARDIOVASCULAR diseases , *LIPID metabolism , *PREBIOTICS - Abstract
Aims: The consumption of prebiotics has been associated with improvement in the lipid profile. Thus, this review aims to describe the main mechanisms by which inulin-type fructans improve the lipid profile and thereby reduce the cardiovascular risk. Data synthesis: Inulin-type fructans have been demonstrated to improve the lipid profile through a number of mechanisms. These mechanisms include: decrease in gene expression of hepatic enzymes responsible for de novo synthesis of lipids; increase of muscle lipoprotein lipase enzyme activity, enhancing the production of short-chain fatty acids; altered production of polyamines which increases the production of satiogenic peptide; altered blood glucose and insulinemia; increase of fecal excretion of bile salts and cholesterol and increase of the Bifidobacterium population. Conclusions: The consumption of inulin-type fructans enhances lipid profile. Generally, the mechanisms vary according to the physiologic state of the individual and the type of diet to which the inulin-type fructans are added. Thus, inulin may be used for the prevention and/or treatment of cardiovascular diseases. [ABSTRACT FROM AUTHOR]
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- 2015
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