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Mechanisms used by inulin-type fructans to improve the lipid profile.
- Source :
-
Nutrición Hospitalaria . feb2015, Vol. 31 Issue 2, p528-534. 7p. - Publication Year :
- 2015
-
Abstract
- Aims: The consumption of prebiotics has been associated with improvement in the lipid profile. Thus, this review aims to describe the main mechanisms by which inulin-type fructans improve the lipid profile and thereby reduce the cardiovascular risk. Data synthesis: Inulin-type fructans have been demonstrated to improve the lipid profile through a number of mechanisms. These mechanisms include: decrease in gene expression of hepatic enzymes responsible for de novo synthesis of lipids; increase of muscle lipoprotein lipase enzyme activity, enhancing the production of short-chain fatty acids; altered production of polyamines which increases the production of satiogenic peptide; altered blood glucose and insulinemia; increase of fecal excretion of bile salts and cholesterol and increase of the Bifidobacterium population. Conclusions: The consumption of inulin-type fructans enhances lipid profile. Generally, the mechanisms vary according to the physiologic state of the individual and the type of diet to which the inulin-type fructans are added. Thus, inulin may be used for the prevention and/or treatment of cardiovascular diseases. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02121611
- Volume :
- 31
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Nutrición Hospitalaria
- Publication Type :
- Academic Journal
- Accession number :
- 100872918
- Full Text :
- https://doi.org/10.3305/nh.2015.31.2.7706