521 results on '"Gopalakrishnan, Murali"'
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2. Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats
3. A-306989, an inhibitor of adenosine kinase, is renoprotective in rodent models of podocyte, basement membrane, and obstructive injury
4. On Becoming a Pharmacologist: Channeling David Triggle
5. Annular Swirling Jet Reactor for Converting Hydrocarbons to Olefins and Aromatics with Net-Zero Carbon Emissions
6. Potassium Channels
7. Effects of the Novel α7 Nicotinic Acetylcholine Receptor Agonist ABT-107 on Sensory Gating in DBA/2 Mice: Pharmacodynamic Characterization
8. Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as revealed by subtype selective agonists
9. KCNQ2/3 openers show differential selectivity and site of action across multiple KCNQ channels
10. α4β2 neuronal nicotinic receptor positive allosteric modulation: An approach for improving the therapeutic index of α4β2 nAChR agonists in pain
11. Potentiation of analgesic efficacy but not side effects: Co-administration of an α4β2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats
12. Receptor regulation
13. α7 nAChR-mediated activation of MAP kinase pathways in PC12 cells
14. α3* and α7 nAChR-mediated Ca 2+ transient generation in IMR-32 neuroblastoma cells
15. Importance of M2–M3 loop in governing properties of genistein at the α7 nicotinic acetylcholine receptor inferred from α7/5-HT 3A chimera
16. A Festschrift in honor of David J. Triggle
17. In Vitro Pharmacological Characterization of a Novel Allosteric Modulator of α7 Neuronal Acetylcholine Receptor, 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), Exhibiting Unique Pharmacological Profile
18. Characterization of human cannabinoid CB 2 receptor coupled to chimeric Gα qi5 and Gα qo5 proteins
19. Selective α7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3β and decreases tau phosphorylation in vivo
20. Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity α4β2 subunit combination
21. Selectivity of ABT-089 for α4β2* and α6β2* nicotinic acetylcholine receptors in brain
22. Effects of α7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis
23. [3H]A-585539 [(1 S,4 S)-2,2-Dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a Novel High-Affinity α7 Neuronal Nicotinic Receptor Agonist: Radioligand Binding Characterization to Rat and Human Brain
24. Analysis of gene expression profiles in rat hippocampus following treatment with nicotine and an α7 nAChR selective agonist
25. Characterization of human ASIC2a homomeric channels stably expressed in murine Ltk − cells
26. An Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor Possessing Cognition-Enhancing Properties in Vivo
27. Distinct Profiles of α7 nAChR Positive Allosteric Modulation Revealed by Structurally Diverse Chemotypes
28. α4β2 Nicotinic receptor stimulation contributes to the effects of nicotine in the DBA/2 mouse model of sensory gating
29. Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists
30. High content screen microscopy analysis of Aβ 1–42-induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands
31. Allosteric modulation of nicotinic acetylcholine receptors
32. Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys
33. Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle
34. Association of Catsper1 or -2 with Cav3.3 Leads to Suppression of T-type Calcium Channel Activity
35. ( l)-Phenylglycine, but not necessarily other α 2δ subunit voltage-gated calcium channel ligands, attenuates neuropathic pain in rats
36. Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs
37. Block of hERG channel by ziprasidone: Biophysical properties and molecular determinants
38. α7 NNR allosteric modulation in behavioral models of cognition: 2.19
39. In Vitro neuroprotective effects of ABT-779, a positive allosteric modulator of α7 nAChRs: 2.18
40. A-582941, a pro-cognitive α7 nAChR agonist, differentially modulates mitochondrial membrane potential: 1.11
41. In vitro pharmacological characterization of ABT-779, a novel positive allosteric modulator of α7 nAChRs: 1.20
42. Nicotinic acetylcholine receptors as therapeutic targets: Emerging frontiers in basic research and clinical science—Editorial Comments
43. Importance of M2–M3 loop in governing properties of genistein at the α7 nicotinic acetylcholine receptor inferred from α7/5-HT3A chimera
44. α3* and α7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells
45. Positive allosteric modulation of α7 neuronal nicotinic acetylcholine receptors: lack of cytotoxicity in PC12 cells and rat primary cortical neurons
46. Role of channel activation in cognitive enhancement mediated by α7 nicotinic acetylcholine receptors
47. Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as Revealed by subtype selective agonists: 5.6
48. Improving the efficacy-tolerability profile of nAChR agonists for the treatment of neuropathic pain in combination with positive allosteric modulators: 4.2
49. In vivo characterization of the co-administration of α4β2 neuronal nicotinic receptor agonist and positive allosteric modulator in experimental pain in rats: 4.3
50. Positive allosteric modulation of α7 neuronal nicotinic acetylcholine receptors: Lack of mechanism-based evidence for cytotoxicity in PC12 cells and rat primary cortical neurons: 1.13
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