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126 results on '"Goldstein, Jacqueline I."'

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1. Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes

2. Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

3. Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia

4. Identification of common genetic risk variants for autism spectrum disorder

5. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.

6. Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes

7. Mapping genomic loci implicates genes and synaptic biology in schizophrenia

8. Pan-UK Biobank GWAS improves discovery, analysis of genetic architecture, and resolution into ancestry-enriched effects

9. A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.

10. Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

11. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

12. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

13. Biological insights from 108 schizophrenia-associated genetic loci

14. Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

16. A second update on mapping the human genetic architecture of COVID-19

17. A polygenic resilience score moderates the genetic risk for schizophrenia

18. Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia

19. Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

20. Mapping genomic loci implicates genes and synaptic biology in schizophrenia

21. Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia

22. Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

23. A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

24. Systematic single-variant and gene-based association testing of thousands of phenotypes in 426,370 UK Biobank exomes

25. Mapping the human genetic architecture of COVID-19

26. Complement genes contribute sex-biased vulnerability in diverse disorders

28. Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

29. Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

30. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

31. Age at first birth in women is genetically associated with increased risk of schizophrenia

32. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

33. Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

34. Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

35. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

36. Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

37. No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

38. Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

39. Biological insights from 108 schizophrenia-associated genetic loci

40. Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

42. Population‐based identity‐by‐descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

43. zCall: a rare variant caller for array-based genotyping

44. Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

45. Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles

46. Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration

47. Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

48. Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

49. Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

50. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

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