1. Attainment of EULAR/ERA-EDTA targets of therapy with current immunosuppressive regimens and adjustments in treatment: a multicentre, real-life observational study
- Author
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Dimitrios T Boumpas, Antonis Fanouriakis, Prodromos Sidiropoulos, George Bertsias, Maria G Tektonidou, Petros P Sfikakis, Antigone Pieta, Dimitrios Vassilopoulos, Maria Pappa, Paraskevi V Voulgari, Myrto Nikoloudaki, Theodoros Dimitroulas, Andreas Goules, Charalampos Papagoras, Christina Tsalapaki, Kyriaki A Boki, Harikleia Gakiopoulou, Maria Kosmetatou, Evangelia Argyriou, Aglaia Chalkia, Georgios Demirtzoglou, Christina Katsiari, Nektarios Marios Liapis, Myrto Cheila, and George Liapis
- Subjects
Medicine - Abstract
Objective To estimate real-life European Alliance of Associations for Rheumatology (EULAR)/European Renal Association (ERA)-European Dialysis and Transplantation Association (EDTA) response rates and predictors for no response in patients with lupus nephritis (LN) managed with conventional immunosuppressive therapies.Methods Ambidirectional cohort study of patients with new-onset LN (period 2014–to date). Response rates in the first year were calculated, and all treatment modifications were recorded. Univariate and multivariate regression analyses were performed to assess determinants of failure to respond at 12 months.Results 140 patients were included (81.4% women, median (IQR) age at LN diagnosis 38 (22) years). Among them, 32.1% presented with nephrotic range proteinuria, 28.6% with glomerular filtration rate
- Published
- 2024
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