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5 results on '"Gayathri Naraparaju"'

1. Correction: Sakulsaengprapha et al. Applicability of International Autoimmune Hepatitis Group (IAIHG) Scoring System for Autoimmune Hepatitis in Pediatrics. Biology 2023, 12, 479

Author

Vorada Sakulsaengprapha, Paul Wasuwanich, Gayathri Naraparaju, Yelena Korotkaya, Supharerk Thawillarp, Kiyoko Oshima, Christine Karwowski, Ann O. Scheimann, and Wikrom Karnsakul

Subjects
n/a, Biology (General), QH301-705.5
Abstract

There was a spelling mistake in the original publication [...]

Published
2023
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2. Applicability of International Autoimmune Hepatitis Group (IAIHG) Scoring System for Autoimmune Hepatitis in Pediatrics

Author

Vorada Sakulsaengprapha, Paul Wasuwanich, Gayathri Naraparaju, Yelena Korotkaya, Supharerk Thawillarp, Kiyoko Oshima, Christine Karwowski, Ann O. Scheimann, and Wikrom Karnsakul

Subjects
liver diseases, biopsy, pathology, public health, Biology (General), QH301-705.5
Abstract

Introduction: Many hepatologic pathologies mimic autoimmune hepatitis (AIH). Researchers developed the International Autoimmune Hepatitis Group (IAIHG) scoring system to compensate for the lack of specific diagnostic tests for AIH. The scoring system was not designed with pediatric patients in mind, so there are limits to its pediatric use. Additionally, there is limited information on the value of a liver biopsy in conjunction with its use. Methods: In this retrospective study, we evaluated the effect of liver biopsy scores on the IAIHG scoring system in patients that were 0–18 years old with suspected AIH. We also analyzed demographic data and laboratory values associated with a final AIH diagnosis. Results: We found that interface hepatitis and predominant plasma cells found during the biopsy were significantly associated with a final AIH diagnosis. We also found that abnormal laboratory values were associated with an AIH diagnosis. We found that IAIHG scores calculated post-liver biopsy showed a greater area under the receiver operating characteristic curve (AUROC) of 0.95, which was compared to 0.88 for the scores calculated before a liver biopsy. Including biopsy metrics lowered the optimized cutoff score and test specificity. Conclusion: Incorporating liver histopathological features improved the performance of the IAIHG scoring system. Further studies to identify other potential elements in liver histology may improve the performance metrics of the IAIHG test in the pediatric population.

Published
2023
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3. Digital Wings: Innovations in Transplant Readiness for Adolescent and Young Adult Transplant Recipients

Author

Natalie Williams, Macey L. Henderson, Michael Fergusson, Ryan Ford, Dorry L. Segev, John F.P. Bridges, Douglas Mogul, Jon Hochstein, Emily M. Fredericks, Beverly Kosmach-Park, Kristin A. Riekert, Tammy M. Brady, Tamir Miloh, and Gayathri Naraparaju

Subjects
Transplantation, medicine.medical_specialty, education.field_of_study, business.industry, Population, MEDLINE, 030230 surgery, 03 medical and health sciences, 0302 clinical medicine, Family medicine, medicine, 030211 gastroenterology & hepatology, Intersectoral Collaboration, Young adult, Solid organ transplantation, education, Biomedical technology, business, Transfer of care
Abstract

The Johns Hopkins University School of Medicine organized 2 multistakeholder symposia on February 2, 2018 and January 11, 2019 to address the problem of high graft failure in adolescent and young adult (AYA) solid organ transplant (SOT) recipients. Participants included international experts in transplantation, behavioral psychology, patient/parent advocacy, and technology. The objectives of the symposia were as follows: (1) to identify and discuss the barriers to and facilitators of effective transfer of care for AYA SOT recipients; (2) to actively explore strategies and digital solutions to promote their successful transfer of care; and (3) to develop meaningful partnerships for the successful development, evaluation, implementation, and dissemination of these digital solutions. Additionally, data were collected from 152 AYA SOT recipients demonstrating a substantial gap in how this population uses technologies for health-related activities, alongside an increased interest in an app to help them manage their transplant.

Published
2019
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4. Digital Wings: Innovations in Transition Readiness for Adolescent and Young Adult Transplant Recipients [corrected]

Author

Douglas B, Mogul, Emily M, Fredericks, Tammy M, Brady, Tamir, Miloh, Kristin, Riekert, Natalie, Williams, Ryan, Ford, Michael, Fergusson, Beverly, Kosmach-Park, Jon, Hochstein, Gayathri, Naraparaju, Macey L, Henderson, Dorry L, Segev, and John F P, Bridges

Subjects
Graft Rejection, Transition to Adult Care, Young Adult, Adolescent, Inventions, Adolescent Behavior, Biomedical Technology, Health Plan Implementation, Humans, Organ Transplantation, Intersectoral Collaboration, Mobile Applications, Transplant Recipients
Abstract

The Johns Hopkins University School of Medicine organized 2 multistakeholder symposia on February 2, 2018 and January 11, 2019 to address the problem of high graft failure in adolescent and young adult (AYA) solid organ transplant (SOT) recipients. Participants included international experts in transplantation, behavioral psychology, patient/parent advocacy, and technology. The objectives of the symposia were as follows: (1) to identify and discuss the barriers to and facilitators of effective transfer of care for AYA SOT recipients; (2) to actively explore strategies and digital solutions to promote their successful transfer of care; and (3) to develop meaningful partnerships for the successful development, evaluation, implementation, and dissemination of these digital solutions. Additionally, data were collected from 152 AYA SOT recipients demonstrating a substantial gap in how this population uses technologies for health-related activities, alongside an increased interest in an app to help them manage their transplant.

Published
2019

5. Diffuse Gastric Bleed Managed With Hemospray in a 15-Year-old Patient

Author

Douglas Mogul, Kenneth Ng, and Gayathri Naraparaju

Subjects
Male, Minerals, medicine.medical_specialty, Adolescent, business.industry, General surgery, Video Recording, Gastroenterology, Gastric bleed, Diagnosis, Differential, Text mining, Melena, Gastritis, Pediatrics, Perinatology and Child Health, medicine, Humans, Endoscopy, Digestive System, Gastrointestinal Hemorrhage, business
Published
2019
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