1. Bioefficacy of L-lysine sulfate compared with feed-grade L-lysine-HCl in young pigs.
- Author
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Smiricky-Tjardes MR, Mavromichalis I, Albin DM, Wubben JE, Rademacher M, and Gabert VM
- Subjects
- Animals, Biological Availability, Dose-Response Relationship, Drug, Female, Lysine administration & dosage, Lysine analogs & derivatives, Male, Nutritive Value, Random Allocation, Regression Analysis, Swine metabolism, Animal Feed, Animal Nutritional Physiological Phenomena, Eating drug effects, Lysine pharmacokinetics, Swine growth & development, Weight Gain drug effects
- Abstract
A pig growth assay was conducted to determine the relative biological value (RBV) of lysine from L-lysine sulfate compared with feed-grade L-lysine HCl. One hundred nursery pigs with an average initial BW of 9.5 +/- 1.5 kg were blocked by BW and gender and allotted randomly to five dietary treatments in five replicates of four pigs per pen. A corn-peanut meal diet containing 0.6% total lysine (as-fed basis) was supplemented with two levels (0.1 and 0.2%) of lysine from L-lysine-HCl or L-lysine sulfate. The RBV of L-lysine sulfate was determined using multiple regression slope-ratio methodology, with ADG and G:F as the response criteria. At the tested levels, linear responses for gain and G:F were obtained from increments of lysine from the two lysine sources. When ADG was regressed on supplemental lysine intake, the RBV of lysine in L-lysine sulfate was 99% of the RBV of lysine in L-lysine HCl. When G:F was regressed on supplemental lysine intake, the RBV of lysine in L-lysine sulfate was 97% of the RBV of lysine in L-lysine-HCl. The t-test analysis revealed that the RBV of lysine in L-lysine sulfate was not significantly different from the RBV of lysine in L-lysine HCl, which was assumed to be 100% bioavailable. In conclusion, L-lysine sulfate can replace L-lysine HCl in diets for growing swine.
- Published
- 2004
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