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Bioefficacy of L-lysine sulfate compared with feed-grade L-lysine-HCl in young pigs.
- Source :
-
Journal of animal science [J Anim Sci] 2004 Sep; Vol. 82 (9), pp. 2610-4. - Publication Year :
- 2004
-
Abstract
- A pig growth assay was conducted to determine the relative biological value (RBV) of lysine from L-lysine sulfate compared with feed-grade L-lysine HCl. One hundred nursery pigs with an average initial BW of 9.5 +/- 1.5 kg were blocked by BW and gender and allotted randomly to five dietary treatments in five replicates of four pigs per pen. A corn-peanut meal diet containing 0.6% total lysine (as-fed basis) was supplemented with two levels (0.1 and 0.2%) of lysine from L-lysine-HCl or L-lysine sulfate. The RBV of L-lysine sulfate was determined using multiple regression slope-ratio methodology, with ADG and G:F as the response criteria. At the tested levels, linear responses for gain and G:F were obtained from increments of lysine from the two lysine sources. When ADG was regressed on supplemental lysine intake, the RBV of lysine in L-lysine sulfate was 99% of the RBV of lysine in L-lysine HCl. When G:F was regressed on supplemental lysine intake, the RBV of lysine in L-lysine sulfate was 97% of the RBV of lysine in L-lysine-HCl. The t-test analysis revealed that the RBV of lysine in L-lysine sulfate was not significantly different from the RBV of lysine in L-lysine HCl, which was assumed to be 100% bioavailable. In conclusion, L-lysine sulfate can replace L-lysine HCl in diets for growing swine.
- Subjects :
- Animals
Biological Availability
Dose-Response Relationship, Drug
Female
Lysine administration & dosage
Lysine analogs & derivatives
Male
Nutritive Value
Random Allocation
Regression Analysis
Swine metabolism
Animal Feed
Animal Nutritional Physiological Phenomena
Eating drug effects
Lysine pharmacokinetics
Swine growth & development
Weight Gain drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0021-8812
- Volume :
- 82
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Journal of animal science
- Publication Type :
- Academic Journal
- Accession number :
- 15446477
- Full Text :
- https://doi.org/10.2527/2004.8292610x