152 results on '"G Sahar"'
Search Results
2. An association between oxygen desaturation and D-dimer in patients with obstructive sleep apnea syndrome
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Nir Peled, Mordechai R. Kramer, G Sahar, David Shitrit, Silvia Meidan, Daniel Bendayan, and Ariella Bar-Gil Shitrit
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Male ,medicine.medical_specialty ,Time Factors ,Polysomnography ,Fibrin Fibrinogen Degradation Products ,Predictive Value of Tests ,Surveys and Questionnaires ,Internal medicine ,D-dimer ,Respiratory disturbance index ,medicine ,Humans ,Prospective Studies ,Platelet activation ,Aged ,Oxygen saturation (medicine) ,Aged, 80 and over ,Sleep Apnea, Obstructive ,medicine.diagnostic_test ,business.industry ,Respiratory disease ,Sleep apnea ,Hematology ,Middle Aged ,medicine.disease ,Surgery ,Oxygen ,Obstructive sleep apnea ,Cardiology ,Female ,business - Abstract
SummaryD-dimer, a degradation product of fibrin, is being increasingly used as a marker and prognostic factor in various thrombotic diseases. Previous reports have shown that obstructive sleep apnea is associated with platelet activation and hypercoagulability. The aim of the study was to assess the potential role of the plasma D-dimer test in patients with obstructive sleep apnea. We designed a prospective group comparison study in a tertiary- care, university-affiliated medical center. One hundred and three patients of mean age 57 years (range 50–76 years) with symptoms suggestive of obstructive sleep apnea were included. Polysomnography was performed in all cases, and blood was collected for plasma D-dimer measurement by MiniQuant turbidmetric assay. The demographic and polysomnograph data were compared between patients with normal and high (>250 ng/ml) D-dimer levels. The group with higher D-dimer values had lower mean minimal oxygen saturation (72.1±16.4 vs. 81.7±11.6%, p=0.008) and a longer mean period of oxygen saturation below 90% (84.1±86.2 vs. 38.5±70.8 minutes, p=0.032). There was no correlation of respiratory disturbance index and sleep architecture with D-dimer values. We concluded that sleep apnea syndrome is associated with fibrinolytic activity. Oxygen desaturation seems to be one of the mediatory factors in the putative connection between obstructive sleep apnea and hypercoagulability state.
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- 2005
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3. Paranoia: When criminology predicts vocational prognosis
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G. Sahar, B. Imen, R. Rim, and B. Ghajati
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medicine.medical_specialty ,Acting out ,Delusional disorder ,media_common.quotation_subject ,Jealousy ,Erotomania ,medicine.disease ,Mental health ,Psychiatry and Mental health ,Insanity ,medicine ,Paranoia ,medicine.symptom ,Psychiatry ,Psychology ,Clinical psychology ,media_common ,Persecution - Abstract
Patients with paranoia have always been a group of exiting but daunting patients for mental health professionals. Indeed, the risk of a violent acting out with important aggressive discharges confers to these patients an elevated dangerosity potential. If various criminological aspects of violence in paranoia have been described, their link to functional prognosis of patients have been seldom addressed.AimTo determine if criminological details of violence acts in paranoia patients predict their functional prognosis.MethodsA retrospective, descriptive and analytic study have been conducted, based on a chart consult. Twenty-three patients with paranoia (i.e. Chronic delusional disorder type jealousy or erotomania in DSM IV) patients have been included. These patients have been hospitalized in the forensic psychiatry department of Razi hospital of Tunis (Tunisia), between 1995 and 2015, after not being held by reason of insanity, according to article 38 of the Tunisian Criminal Code.ResultsDelusional disorder types were: jealousy (17), persecution (4), erotomania (1) and claim (1). The majority were married (18), undereducated (17), with irregular work (13). Forensic acts were uxoricide (15), attempted murder (5), violence against people (2) and destruction of public properties (1). Patients used bladed weapon in most of the cases (13), in the victim's residence (19), with premeditation in (17) of the crimes. Only 5 patients worked regularly after discharge.ConclusionIf our results expose further data concerning potential dangerosity of patients with delusional disorders, they also highlight the marginalized situation of these patients when released back into society.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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- 2017
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4. Failure to Detect Chlamydia pneumoniae by Cell Culture and Polymerase Chain Reaction in Major Arteries of 93 Patients with Atherosclerosis
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A. Vojdani, G. Sahar, Jihad Bishara, S. Rosenberg, M. Haddad, Zmira Samra, Silvio Pitlik, and A. Kazakov
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DNA, Bacterial ,Male ,Microbiology (medical) ,Pathology ,medicine.medical_specialty ,medicine.medical_treatment ,Molecular Sequence Data ,Coronary Artery Disease ,Carotid endarterectomy ,medicine.disease_cause ,Polymerase Chain Reaction ,Risk Assessment ,Sensitivity and Specificity ,law.invention ,Cohort Studies ,Medical microbiology ,law ,Preoperative Care ,medicine ,Humans ,Carotid Stenosis ,Chlamydiaceae ,Prospective Studies ,Coronary Artery Bypass ,False Negative Reactions ,Cells, Cultured ,Polymerase chain reaction ,Aged ,Aged, 80 and over ,Endarterectomy, Carotid ,Chlamydia ,Base Sequence ,biology ,General Medicine ,Chlamydia Infections ,Chlamydophila pneumoniae ,Middle Aged ,biology.organism_classification ,medicine.disease ,Infectious Diseases ,Cell culture ,Chlamydiales ,cardiovascular system ,Female - Abstract
To detect Chlamydia pneumoniae in punch specimens of the aortic wall of 61 patients undergoing coronary-aortic bypass graft, and carotid atheromas of 32 patients undergoing carotid endarterectomy, cell culture (HEp-2 cells) and two polymerase chain reaction assays in two different laboratories were used. All cultures and polymerase chain reaction tests for Chlamydia pneumoniae were negative. Further studies are required to explore the complex relationship between Chlamydia pneumoniae and atherosclerosis.
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- 2003
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5. Outcome of unrelated surgical procedures among patients who received heart transplants
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E Raanani, Dan Aravot, G Sahar, T Ben Gal, M Berman, Georgios P. Georghiou, A Kogan, Leonid A. Eidelman, Bernardo A. Vidne, Z Zibly, and M Menashrov
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Heart transplants ,Transplantation ,medicine.medical_specialty ,Antecedent (logic) ,business.industry ,Cataract Extraction ,Middle Aged ,Surgical procedures ,Outcome (game theory) ,Postoperative Complications ,Treatment Outcome ,medicine ,Heart Transplantation ,Humans ,Surgery ,Postoperative Period ,Intensive care medicine ,business ,Herniorrhaphy ,Retrospective Studies - Published
- 2003
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6. Long-term physical training in cardiac transplant candidates: is it feasible?
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M Berman, Tuvia Ben-Gal, G Sahar, Dan Aravot, Nili Zafrir, and A Pinchas
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Heart Failure ,Transplantation ,medicine.medical_specialty ,Waiting Lists ,business.industry ,Hemodynamics ,Training (meteorology) ,Prognosis ,Ventricular Function, Left ,Term (time) ,Oxygen Consumption ,Exercise Test ,Respiratory Mechanics ,Physical therapy ,Heart Transplantation ,Humans ,Medicine ,Surgery ,Cardiomyopathies ,business ,Exercise - Published
- 2000
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7. Critical oxygen delivery during cardiopulmonary bypass in dogs: pulsatile vs. non-pulsatile blood flow
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M. Blauwaert, A. Deltell, S. De Hert, Y. Bekkrar, G. Sahar, Sylvain Bélisle, Jean Louis Vincent, P. Van der Linden, and Anesthesiology
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Pulsatile flow ,chemistry.chemical_element ,Oxygen ,Constriction ,law.invention ,chemistry.chemical_compound ,Dogs ,Oxygen Consumption ,law ,Cardiopulmonary bypass ,Medicine ,Animals ,Anesthesia ,Lactic Acid ,Cardiopulmonary Bypass ,business.industry ,Blood flow ,Lactic acid ,Pump flow ,Anesthesiology and Pain Medicine ,chemistry ,Oxygen delivery ,business ,Algorithms - Abstract
BACKGROUND AND OBJECTIVE: To determine the minimal oxygen delivery and pump flow that can maintain systemic oxygen uptake during normothermic (37 degrees C) pulsatile and non-pulsatile cardiopulmonary bypass in dogs. METHODS: Eighteen anaesthetized dogs were randomly assigned to receive either non-pulsatile (Group C; n = 9) or pulsatile bypass flow (Group P; n = 9). Oxygen delivery was reduced by a progressive decrease in pump flow, while arterial oxygen content was maintained constant. In each animal, critical oxygen delivery was determined from plots of oxygen uptake vs. oxygen delivery and from plots of blood lactate vs. oxygen delivery using a least sum of squares technique. Critical pump flow was determined from plots of lactate vs. pump flow. RESULTS: At the critical point, oxygen delivery obtained from oxygen uptake was 7.7 +/- 1.1 mL min(-1) kg(-1) in Group C and 6.8 +/- 1.8 mL min(-1) kg(-1) in Group P (n.s.). These values were similar to those obtained from lactate measurements (Group C: 7.8 +/- 1.6 mL min(-1) kg(-1); Group P: 7.6 +/- 2.0 mL min(-1) kg(-1)). Critical pump flows determined from lactate measurements were 55.6 +/- 13.8 mL min(-1) kg(-1) in Group C and 60.8 +/- 13.9 mL min(-1) kg(-1) in Group P (n.s.). CONCLUSIONS: Oxygen delivery values greater than 7-8 mL min(-1) kg(-1) were required to maintain oxygen uptake during normothermic cardiopulmonary bypass with either pulsatile or non-pulsatile blood flow. Elevation of blood lactate levels during bypass helps to identify inadequate tissue oxygen delivery related to insufficient pump flow
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- 2006
8. Gastrointestinal involvement of posttransplant lymphoproliferative disorder in lung transplant recipients: report of a case
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Milton Saute, Ram Dickman, G Sahar, David Shitrit, Mordechai R. Kramer, and Ariella Bar-Gil Shitrit
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Male ,medicine.medical_specialty ,Abdominal pain ,Lymphoma, B-Cell ,Nausea ,medicine.medical_treatment ,Pulmonary Fibrosis ,Colonoscopy ,Gastroenterology ,Internal medicine ,medicine ,Lung transplantation ,Humans ,Aged ,Gastrointestinal tract ,medicine.diagnostic_test ,business.industry ,Stomach ,General Medicine ,Surgery ,Transplantation ,medicine.anatomical_structure ,Colonic Neoplasms ,medicine.symptom ,Complication ,business ,Lung Transplantation - Abstract
Lymphoproliferative disorder is a well-recognized complication of lung transplantation. Risk factors include Epstein-Barr virus infection and immuno-suppression. The gastrointestinal manifestations of posttransplant lymphoproliferative disorder in lung transplant recipients have not been fully characterized. Case presentation and 16 previously reported cases of posttransplant lymphoproliferative disorder with gastrointestinal involvement are reviewed. Patient ages ranged from 25 to 65 (median, 52) years. Median time from lung transplantation to onset of posttransplant lymphoproliferative disorder was 36 (range, 1–109) months; 35 percent of cases (6/17) occurred within 18 months; Eighty-eight percent of patients (15/17) had positive Epstein-Barr virus serology before transplantation. In five patients (29 percent), the posttransplant lymphoproliferative disorder also involved sites other than the gastrointestinal tract. The most common gastrointestinal site of posttransplant lymphoproliferative disorder was the colon, followed by the small intestine and stomach. Clinical features included abdominal pain, nausea, and bloody diarrhea. Diagnosis was based on typical pathologic changes on gastrointestinal tract biopsy obtained mainly by colonoscopy. Treatment included a reduction in the immunosuppressive regimen in 15 of 17 cases (88 percent) and surgical resection in 10 (59 percent). One patient was untreated. Seven of 16 patients (44 percent) responded to treatment and 9 patients died. Median time from onset of posttransplant lymphoproliferative disorder to death was 70 (range, 10–85) days. Posttransplant lymphoproliferative disorder with gastrointestinal involvement is a unique entity that should be considered in all Epstein-Barr-Virus-positive lung transplant recipients who present with abdominal symptoms. Although immunosuppressive modulation and resection can lead to remission, the risk of death is 50 percent.
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- 2005
9. Atherosclerosis of the aorta is common in patients with severe aortic stenosis: an intraoperative transesophageal echocardiographic study
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Yael Sahar, G Sahar, Yaron Shapira, Bernardo A. Vidne, Alex Sagie, Daniel Weisenberg, and Zaza Iakobishvili
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Thorax ,Pulmonary and Respiratory Medicine ,Adult ,Male ,medicine.medical_specialty ,Arteriosclerosis ,Aortic Diseases ,Aorta, Thoracic ,Comorbidity ,Lesion ,Intraoperative Period ,Aortic valve replacement ,medicine.artery ,Internal medicine ,Medicine ,Humans ,cardiovascular diseases ,Aged ,Aged, 80 and over ,Aorta ,business.industry ,Vascular disease ,Aortic Valve Stenosis ,Middle Aged ,medicine.disease ,Stenosis ,Cardiology ,cardiovascular system ,Surgery ,Female ,Radiology ,Aortic valve calcification ,medicine.symptom ,business ,Cardiology and Cardiovascular Medicine ,Echocardiography, Transesophageal - Abstract
ObjectiveSeveral studies have recently reported an association between aortic valve calcification and atherosclerosis of the cardiovascular system, suggesting that aortic valve calcification might represent an atherosclerosis-like process. Hence the aim of the present study was to determine whether there is a similar association between aortic stenosis and aortic atheromas.MethodsWe evaluated the records and echocardiographic videotapes of 91 consecutive patients with severe aortic stenosis who underwent intraoperative transesophageal echocardiography before aortic valve replacement to measure the presence and characteristics of aortic atheromas. There were 50 men (55%) and 41 women (45%). The mean age was 71.9 ± 9.4 years (range, 34–91 years). These patients were compared with 91 sex-and age-matched patients without aortic stenosis who underwent transesophageal echocardiography for various indications. Aortic atheroma was defined as localized intimal thickening of 3 mm or larger. A lesion was considered complex if there was a plaque extending 5 mm or more into the aortic lumen; if the lesion was protruding, mobile, or ulcerated; or both.ResultsThe aortic stenosis group had significantly higher rates of aortic atheromas (85% vs 37%, P < .001) and complex atheromas (47% vs 9%, P < .001) compared with the control group. In the vast majority of patients in the aortic stenosis group, the aortic atheromas were localized in the aortic arch (60 [66%] patients, with 50% being complex aortic atheromas) and in the descending aorta (70 [77%] patients, with 45.7% being complex aortic atheromas); in only 4 (4.4%) patients, the aortic atheromas were localized in the ascending aorta (50% complex aortic atheromas).ConclusionsThere is a strong association between the presence of severe aortic stenosis and the presence and severity of aortic atheromas, suggesting that aortic stenosis might be a manifestation of the atherosclerotic process. These findings imply that (1) aggressive atherosclerotic risk-factor modification for patients with aortic stenosis might be advisable and (2) consideration of evaluation of the aorta by means of transesophageal echocardiography before aortic valve replacement in selected patients might be helpful.
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- 2005
10. Planning a minimum-time trajectories for robot arms
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J. Hollerbach and G. Sahar
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Computer science ,business.industry ,Arm solution ,Control engineering ,Robotics ,Workspace ,Kinematics ,Curvature ,Control theory ,Trajectory ,Robot ,Artificial intelligence ,Motion planning ,business ,Actuator ,Robotic arm - Abstract
The minimum-time path for a robot arm has been a long-standing and unsolved problem of considerable interest. We present a general solution to this problem that involves joint-space tesselation, a dynamic time-scaling algorithm, and graph search. The solution incorporates full dynamics of movement and actuator constraints, and can be easily extended for joint limits and workspace obstacles, but is subject to the particular tesselation scheme used. The results presented show that, in general, the optimal paths are not straight lines, but rather curves in joint-space that utilize the dynamics of the arm and gravity to help in moving the arm faster to its destination. Implementation difficulties due to the tesselation and to combinatorial proliferation of paths are discussed.
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- 2005
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11. Beneficial effect of aspirin on renal function in patients with renal insufficiency postcardiac surgery
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R, Gerrah, S, Ehrlich, S, Tshori, and G, Sahar
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Adult ,Male ,Cardiopulmonary Bypass ,Aspirin ,Anti-Inflammatory Agents, Non-Steroidal ,Coronary Artery Disease ,Middle Aged ,Kidney Function Tests ,Treatment Outcome ,Creatinine ,Preoperative Care ,Humans ,Female ,Renal Insufficiency ,Coronary Artery Bypass ,Aged - Abstract
Renal function is one of the most important prognostic factors following cardiac surgery. Whether aspirin affects cardiopulmonary bypass related renal injury is investigated in this study.Ninety-four patients with impaired renal function (creatinine = or1.5 mg/dl) undergoing coronary artery bypass grafting (CABG) were categorized into 2 groups according to aspirin administration before surgery. Serum creatinine, urinary output and creatinine clearance along with other perioperative factors were compared between the 2 groups prior to surgery, 24 hours and 48 hours following cardiopulmonary bypass.Creatinine levels increased significantly in the second postoperative day only in the non-aspirin (control) group (3.7+/-1.6 vs 2.9+/-1.7 mg/dl, p=0.03). Aspirin (study) group had lower creatinine levels in day 1 (p=0.03) and day 2 (p=0.001). Furthermore, in the study group creatinine clearance was higher in day 1 (34.3+/-14.3 vs 30.9+/-13.1 ml/min, p=0.01) and in day 2 (32.6+/-13.8 vs 26.4+/-9.8 ml, p0.0001). Creatinine levels at discharge were elevated compared to the preoperative levels in the control group (p=0.01). However, the study group had lower creatinine levels at discharge (2.6+/-1.4 vs 3.8+/-1.6 mg/dl, p0.0001). Urinary output was higher in the study group in the first postoperative day compared to the control group (p=0.01). Postoperative bleeding was slightly increased in the study group compared to the control group (760+/-230 ml vs 530+/-210 ml, p=0.01).Continuation of aspirin administration until the day of surgery may have a protective effect against renal injury resulting from cardiopulmonary bypass, with only a negligible increase in bleeding. Possible explanations for this effect are antiplatelet activity of aspirin during cardiopulmonary bypass causing inhibition of vasoconstrictive agents like thromboxane, and improvement of renal perfusion by reducing blood viscosity.
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- 2005
12. Itraconazole prophylaxis in lung transplant recipients receiving tacrolimus (FK 506): efficacy and drug interaction
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Ayelet Ollech, Milton Saute, Jacob E. Ollech, Ilana Bakal, David Shitrit, Mordechai R. Kramer, and G Sahar
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Pulmonary and Respiratory Medicine ,Graft Rejection ,medicine.medical_specialty ,Antifungal Agents ,Itraconazole ,medicine.medical_treatment ,Renal function ,chemical and pharmacologic phenomena ,Kidney ,Gastroenterology ,Drug Costs ,Tacrolimus ,Pharmacotherapy ,Postoperative Complications ,Internal medicine ,medicine ,Lung transplantation ,Humans ,Drug Interactions ,Transplantation ,business.industry ,Drug interaction ,Surgery ,Calcineurin ,surgical procedures, operative ,Mycoses ,Drug Therapy, Combination ,Cardiology and Cardiovascular Medicine ,business ,Immunosuppressive Agents ,medicine.drug ,Lung Transplantation - Abstract
Itraconazole is often given for fungal prophylaxis to lung transplant recipients after transplantation. The aim of this study was to determine the extent of interaction between tacrolimus and itraconazole in lung transplant recipients and the efficacy of itraconazole prophylaxis.The study group included 40 lung transplant recipients followed for at least 12 months. All received prophylactic itraconazole, 200 mg twice a day, for the first 6 months after transplantation. Tacrolimus levels and dosage requirements were compared during and after itraconazole therapy. Rejection rate, fungal infection rate, and renal function were assessed. The mean cost per daily treatment of the itraconazole/tacrolimus combination and tacrolimus alone was calculated.The mean tacrolimus dose during itraconazole treatment was 3.26 +/- 2.1 mg/day compared with 5.74 +/- 2.9 mg/day after itraconazole was stopped (p0.0001) for a mean total daily dose elevation of tacrolimus of 76%. When the cost of itraconazole was taken into account, the average total daily cost of the combined treatment was US5.86 dollars less than the treatment with tacrolimus alone. No differences in the rejection or fungal infection rate, or in renal toxicity, were observed between the periods with and without itraconazole treatment, although less positive fungal isolates were identified during itraconazole therapy.Prophylaxis therapy with itraconazole is highly effective. Itraconazole reduces the dose of tacrolimus and therefore lowers the cost of therapy without causing an increase in rejection rate and with renal function preservation.
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- 2005
13. Glucose metabolism in heart transplant recipients treated with FK506 or cyclosporine
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Tuvia Ben-Gal, Alexander Kogan, M.R. Kramer, Yaron Shapira, E. Sahar, Milton Saute, R Michowitch, Marius Berman, Bernardo A. Vidne, Alik Sagie, Dan Aravot, and G Sahar
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Blood Glucose ,medicine.medical_specialty ,Time Factors ,Azathioprine ,Tacrolimus ,Diabetes mellitus ,Internal medicine ,Concomitant Therapy ,medicine ,Humans ,Risk factor ,Transplantation ,business.industry ,Mortality rate ,medicine.disease ,Ciclosporin ,Surgery ,Cyclosporine ,Heart Transplantation ,business ,Immunosuppressive Agents ,medicine.drug ,Follow-Up Studies - Abstract
OSTTRANSPLANT diabetes mellitus (PTDM) has gained widespread attention due to the micro- and macrovascular complications that increase the morbidity and mortality rates of patients receiving solid organs. A higher incidence of PTDM has been associated with immunosuppressive therapy. This study compares glucose metabolism in heart transplant recipients receiving either FK506 or cyclosporine. METHODS Two groups of heart transplant recipients, differing in their immunosuppressive regimen—FK506 or cyclosporin—were followed for periods up to 6 years. Blood levels of glucose and of the respective immunosuppressive agent were measured regularly, and, if needed, anti-hyperglycemic treatment prescribed. The concomitant therapy with low-dose steroids and azathioprine was the same for both cohorts. T-test were performed to compare with the mean values of the two groups. RESULTS
- Published
- 2003
14. Persistent high pulmonary artery pressure following orthotopic heart transplantation: inevitable poor prognosis?
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Ehud Raanani, Alexander Kogan, Marius Berman, Bernardo A. Vidne, Dan Aravot, Alon Stamler, T. Ben Gal, G Sahar, and Alik Sagie
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Adult ,Male ,medicine.medical_specialty ,Poor prognosis ,Time Factors ,medicine.medical_treatment ,Hypertension, Pulmonary ,Hemodynamics ,Postoperative Complications ,Predictive Value of Tests ,medicine.artery ,Medicine ,Humans ,Retrospective Studies ,Heart transplantation ,Transplantation ,business.industry ,Middle Aged ,Prognosis ,Predictive factor ,Surgery ,Blood pressure ,medicine.anatomical_structure ,Echocardiography ,Pulmonary artery ,Circulatory system ,Heart Transplantation ,Female ,business ,Blood vessel ,Follow-Up Studies - Published
- 2003
15. Foreign candidates on the transplantation waiting list: an ethical dilemma
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Georgios P. Georghiou, H. Shmuely, Alexander Kogan, Marius Berman, R Michowitch, E. Sahar, Alik Sagie, Bernardo A. Vidne, G Sahar, Dan Aravot, Tuvia Ben-Gal, and Viacheslav Bobovnikov
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medicine.medical_specialty ,education.field_of_study ,Transplantation ,Waiting Lists ,business.industry ,Public health ,Population ,Face (sociological concept) ,Public relations ,Organ transplantation ,Tissue Donors ,Surgery ,General partnership ,Ethical dilemma ,Medicine ,Humans ,business ,education ,Health policy - Abstract
T IS NOW well recognized that the gap between the supply of available transplantable human organs and the need is constantly increasing. Medical suitability is the basis of organ allocation, although the social, economic, psychologic, and demographic situation of each potential recipient represents important considerations. The ethical dilemma that we face is whether foreign, nonresident candidates should be placed on a national waiting list, and, if the answer is positive, under what terms? Organ transplantation, especially heart or lung, requires not only a well-trained group, but also an extensive infrastructure, which does not exist in each country. The lack of organs in the one hand and the lack of infrastructure in other countries on the other hand lead to the need for a mutual partnership among nations. Among the 100 organs transplanted in our center, 3 were donated by nonresident Palestinians who were treated in Israeli hospitals, 1 of whom was a victim of a violent act during the “Intifada.” The Palestinian population, although being provided with diverse medical services, is not entitled to be on the Israeli national waiting list. The ethical question that the medical community faces in these circumstances is whether to accept a family request to donate the organs to a close relative of the donor instead of offering them to all patients on the list. The other debate is whether the waiting list should be equally open to residents and nonresidents, now that they have became part of the potential population to donate.
- Published
- 2003
16. Improved survival after lung transplantation in patients treated with tacrolimus/mycophenolate mofetil as compared with cyclosporine/azathioprine
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M. R. Kramer, G Sahar, M Saute, D Aravot, David Shitrit, Jaqueline Sulkes, and Gabriel Izbicki
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Adult ,Male ,medicine.medical_specialty ,Time Factors ,Heart-Lung Transplantation ,medicine.medical_treatment ,Urology ,Azathioprine ,Mycophenolate ,Mycophenolic acid ,Tacrolimus ,medicine ,Lung transplantation ,Humans ,Transplantation ,business.industry ,Middle Aged ,Mycophenolic Acid ,Ciclosporin ,Survival Analysis ,Surgery ,Calcineurin ,Cyclosporine ,Heart Transplantation ,Drug Therapy, Combination ,Female ,business ,Immunosuppressive Agents ,medicine.drug ,Follow-Up Studies - Published
- 2002
17. Beta-2 microglobulin and serum creatinine for differentiating between immunoactivation and renal failure after liver transplantation
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E. Sharoni, Arie Erman, Ran Tur-Kaspa, D Aravot, Eldad Erez, Bernardo A. Vidne, G Sahar, and Ziv Ben-Ari
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Urology ,Liver transplantation ,Diagnosis, Differential ,chemistry.chemical_compound ,Postoperative Complications ,Internal medicine ,medicine ,Humans ,Renal Insufficiency ,Transplantation ,Creatinine ,business.industry ,Beta-2 microglobulin ,Middle Aged ,medicine.disease ,Liver Transplantation ,Endocrinology ,chemistry ,Regression Analysis ,Surgery ,Female ,business ,Complication ,beta 2-Microglobulin ,Kidney disease - Published
- 2001
18. Successful adolescent bridging to heart transplantation with a left ventricular assist device
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Tuvia Ben-Gal, Dan Aravot, Marius Berman, Leonid A. Eidelman, Bernardo A. Vidne, M Keler, G Sahar, Alik Sagie, Einat Birk, and Ovadia Dagan
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Heart transplantation ,Cardiomyopathy, Dilated ,Transplantation ,medicine.medical_specialty ,Bridging (networking) ,Adolescent ,business.industry ,medicine.medical_treatment ,Treatment Outcome ,Ventricular assist device ,medicine ,Heart Transplantation ,Humans ,Surgery ,Heart-Assist Devices ,Intensive care medicine ,business - Published
- 2001
19. End-stage left ventricular dysfunction associated with extreme clinical right ventricular failure: contraindication for heart transplant?
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G Sahar, M Berman, Dan Aravot, Bernardo A. Vidne, Alexander Battler, Alik Sagie, Nili Zafrir, and Tuvia Ben-Gal
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Male ,Transplantation ,medicine.medical_specialty ,business.industry ,Contraindications ,Ventricular Dysfunction, Right ,Middle Aged ,Surgery ,Ventricular Dysfunction, Left ,Treatment Outcome ,Internal medicine ,medicine ,Cardiology ,Right ventricular failure ,Heart Transplantation ,Humans ,Stage (cooking) ,business ,Contraindication - Published
- 2001
20. Iatrogenic left ventricular-right atrial fistula following mitral valve replacement and tricuspid annuloplasty: diagnosis by transthoracic and transesophageal echocardiography
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J, Benisty, M, Roller, G, Sahar, R, Paz, B, Vidne, and A, Sagie
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Heart Valve Prosthesis Implantation ,Male ,Reoperation ,Mitral Valve Prolapse ,Fistula ,Heart Diseases ,Heart Ventricles ,Iatrogenic Disease ,Tricuspid Valve Insufficiency ,Postoperative Complications ,Echocardiography ,Humans ,Mitral Valve ,Heart Atria ,Tricuspid Valve ,Echocardiography, Transesophageal ,Aged - Abstract
Acquired left ventricle-to-right atrium communications are a known complication of valvular heart surgery. Previous reports have described the clinical features and diagnosis using cardiac catheterization. We report two cases of acquired left ventricle-to-right atrium fistula following mitral valve replacement. Particular emphasis is placed on the diagnosis using transthoracic and transesophageal echocardiography, obviating the need for cardiac catheterization before repair.
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- 2000
21. Natural history of left-sided valves after heart transplantation
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Bernardo A. Vidne, A Sagie, M Vaturi, Tuvia Ben-Gal, Dan Aravot, G Sahar, Shapira Y, and Yehuda Adler
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Heart transplantation ,Male ,Transplantation ,medicine.medical_specialty ,Time Factors ,business.industry ,medicine.medical_treatment ,Aortic Valve Insufficiency ,Follow up studies ,MEDLINE ,Mitral Valve Insufficiency ,Middle Aged ,Left sided ,Surgery ,Natural history ,Echocardiography ,medicine ,Heart Transplantation ,Humans ,Female ,business ,Follow-Up Studies - Published
- 2000
22. Role of cyclosporine in inducing hyperuricemia in heart transplant patients
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Marius Berman, G Sahar, T Ben Gal, Alon Stamler, Dan Aravot, Mordechai Vaturi, and Bernardo A. Vidne
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Purine ,Adult ,medicine.medical_specialty ,medicine.medical_treatment ,Urology ,Renal function ,chemistry.chemical_compound ,Azathioprine ,medicine ,Humans ,Hyperuricemia ,Transplantation ,Kidney ,Chemotherapy ,business.industry ,medicine.disease ,Ciclosporin ,Surgery ,Uric Acid ,Survival Rate ,medicine.anatomical_structure ,chemistry ,Toxicity ,Cyclosporine ,Heart Transplantation ,Prednisone ,Drug Therapy, Combination ,business ,Immunosuppressive Agents ,medicine.drug - Published
- 2000
23. Functional status and quality of life of heart transplant recipients surviving beyond 5 years
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Bernardo A. Vidne, Dan Aravot, Tuvia Ben-Gal, G Sahar, and Marius Berman
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Gerontology ,Adult ,Employment ,Male ,Transplantation ,medicine.medical_specialty ,Time Factors ,business.industry ,Public health ,Sexual Behavior ,Middle Aged ,Quality of life (healthcare) ,Quality of Life ,Medicine ,Heart Transplantation ,Humans ,Surgery ,Functional status ,Female ,Survivors ,business ,Exercise ,Aged ,Follow-Up Studies - Published
- 2000
24. Right atrial dilatation: major contributor to increased cardiothoracic ratio in cardiac transplant candidates
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Mali Mansur, Bernardo A. Vidne, Alik Sagie, Eldad Erez, Marius Berman, Tuvia Ben-Gal, Dan Aravot, and G Sahar
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Male ,Transplantation ,medicine.medical_specialty ,Waiting Lists ,business.industry ,Heart Ventricles ,Heart ,Surgery ,Text mining ,Radiologic sign ,medicine.anatomical_structure ,Cardiothoracic ratio ,Echocardiography ,Medicine ,Right atrium ,Heart Transplantation ,Humans ,Female ,Radiography, Thoracic ,Heart Atria ,Right atrial dilatation ,business - Published
- 1999
25. Differences in immunoactivation between heart and liver transplanted patients
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Bernardo A. Vidne, Z Ben Ari, Ran Tur-Kaspa, Arie Erman, G Sahar, Erez Sharoni, Eldad Erez, and Dan Aravot
- Subjects
Adult ,medicine.medical_specialty ,Graft failure ,Induction immunosuppression ,medicine.medical_treatment ,Azathioprine ,Human leukocyte antigen ,Liver transplantation ,Kidney ,Gastroenterology ,Immune system ,Prednisone ,Reference Values ,Internal medicine ,medicine ,Humans ,Postoperative Period ,Transplantation ,business.industry ,Middle Aged ,Surgery ,Liver Transplantation ,surgical procedures, operative ,Creatinine ,Immune System ,Heart Transplantation ,business ,beta 2-Microglobulin ,medicine.drug - Abstract
HEART and liver transplantation have become the treatment of choice in end-stage heart or liver failure. Advances in surgical technique and the introduction of cyclosporine A have improved survival following transplantation, but allograft rejection is still common and remains a major cause of morbidity and late graft failure. Transplantation results in the recipient’s immune activation, however, because of baseline immunosuppressive therapy only some recipients manifest clinical symptoms of rejection. Induction immunosuppression after heart and liver transplantation has mainly been based on regimens previously used in renal transplantation. Modern regimens use triple-drug treatment: cyclosporine or FK 506, prednisone, and azathioprine for almost all organ recipients without questioning basic differences in immunoactivation. Beta-2-microglobulin (B2m) is a low molecular weight protein associated with HLA class I antigens and is of value for immunologic monitoring. B2m has been shown to significantly increase after heart, liver, or renal transplantation without clinical evidence for rejection. The purpose of this study was to explore differences in immunoactivation between stable heart and liver transplanted patients to improve long-term monitoring and immunosuppressive therapy.
- Published
- 1999
26. Importance of the cardiothoracic ratio in the evaluation of cardiac transplant candidates
- Author
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Marius Berman, Tuvia Ben-Gal, Bernardo A. Vidne, G Sahar, Eldad Erez, and Dan Aravot
- Subjects
Adult ,Male ,Transplantation ,medicine.medical_specialty ,Cardiac Catheterization ,Waiting Lists ,business.industry ,Blood Pressure ,Heart ,Stroke Volume ,Middle Aged ,Pulmonary Artery ,Ventricular Function, Left ,Surgery ,Cardiothoracic ratio ,Oxygen Consumption ,Echocardiography ,medicine ,Heart Transplantation ,Humans ,Female ,Radiography, Thoracic ,business ,Aged - Published
- 1999
27. Outcome and risk factors in octogenarians undergoing open-heart surgery
- Author
-
G, Sahar, D, Abramov, E, Erez, A, Sagie, J, Barak, E, Raanani, J, Sulkes, and B A, Vidne
- Subjects
Aged, 80 and over ,Heart Valve Prosthesis Implantation ,Survival Rate ,Postoperative Complications ,Treatment Outcome ,Risk Factors ,Heart Valve Diseases ,Humans ,Coronary Disease ,Coronary Artery Bypass ,Aged ,Follow-Up Studies ,Retrospective Studies - Abstract
Increasing numbers of elderly (aged80 years) patients are being referred for cardiac surgery, and results for coronary artery bypass grafting (CABG) are generally better than for combined CABG and valve replacement.During the past 55 months, 77 octogenarians underwent cardiac intervention in our institution. Forty-five patients (mean age 82.5 years) underwent CABG alone; surgery was elective in 33% of patients and 2.7 +/- 1.0 grafts per patient were performed. Thirty-two patients (mean age 82.4 years) underwent combined CABG and valve surgery (28 aortic, four mitral); 2.1 +/- 0.8 grafts per patient were performed and 65% of cases were emergencies.In patients undergoing CABG alone, the operative mortality rate was 2% and rose to 4% (n = 2) at the end of follow up. Mean NYHA functional class improved significantly from 3.5 +/- 0.5 to 1.4 +/- 0.3 after surgery (p0.05) and most patients reported marked improvement in their quality of life. In CABG + valve surgery patients, the operative mortality rate was 6% (n = 2) and reached 18% by the end of follow up. In these patients the complication rate was 24% and mean hospitalization stay 11.0 +/- 2.9 days, while mean NYHA functional class improved from 3.4 +/- 0.6 to 1.2 +/- 0.5. Data analysis revealed that mitral regurgitation combined with coronary artery disease (p0.03) and prolonged cross-clamping time (p0.01) were the most important independent factors for mortality.This study confirms that, in selected elderly patients, combined CABG and cardiac surgery can achieve good postoperative results.
- Published
- 1999
28. Tricuspid regurgitation late after mitral valve replacement: clinical and echocardiographic evaluation
- Author
-
A, Porter, Y, Shapira, M, Wurzel, J, Sulkes, M, Vaturi, Y, Adler, G, Sahar, and A, Sagie
- Subjects
Heart Valve Prosthesis Implantation ,Male ,Time Factors ,Hemodynamics ,Mitral Valve Insufficiency ,Middle Aged ,Echocardiography, Doppler ,Tricuspid Valve Insufficiency ,Postoperative Complications ,Humans ,Mitral Valve ,Regression Analysis ,Female ,Blood Flow Velocity ,Aged ,Follow-Up Studies ,Proportional Hazards Models - Abstract
Significant tricuspid regurgitation (TR) can contribute to increased morbidity and mortality in patients after mitral valve replacement (MVR), both in the immediate and late postoperative period. The aim of this study was to evaluate the prevalence and the clinical importance of TR late after MVR, as assessed both clinically and echocardiographically.The study group comprised 65 patients (39 women, 26 men; mean age 61+/-12 years) with rheumatic heart disease who had undergone MVR without tricuspid valve surgery between one and 30 years (mean 11.3+/-8 years) before their last clinical examination. All patients underwent a complete color-Doppler echocardiographic examination. The predominant presurgical mitral lesion was stenosis in 44 patients and regurgitation in 21. The severity of the tricuspid valve disease was assessed echocardiographically using color-Doppler flow images and flow direction in the inferior vena cava or hepatic veins, and by clinical evaluation.Echocardiography revealed significant late TR in 44 patients (67%), which was moderate in 16 and severe in 28, and evident on physical examination in 24 cases (37%). Age (relative risk (RR) = 1.1; C.I. 1-1.1) and female sex (RR = 1.8; C.I. = 1.0-3.2) were identified as statistically significant predictors for late clinical TR development, but only age was found as a statistically significant predictor for echocardiographic TR development. An elevated RR for organic TR and predominant mitral regurgitation was found. In contrast, pre- and postoperative pulmonary artery pressure, predominant mitral lesion, prosthetic valve gradient and regurgitation were similar in patients with and without late TR.Significant TR diagnosed by echocardiography late after MVR is common, and clinically evident in more than one-third of patients. Therefore, a lower threshold for tricuspid valve repair should be considered when mitral valve surgery is carried out.
- Published
- 1999
29. Massive spontaneous hemothorax as a presenting sign of aneurysmal rupture of the internal thoracic artery. A case report
- Author
-
J D, Cohen, G, Sahar, P, Singer, M, Nili, J, Keslin, and B A, Vidne
- Subjects
Adult ,Hemothorax ,Male ,Thoracic Arteries ,Humans ,Aneurysm, Ruptured ,Tomography, X-Ray Computed ,Dilatation, Pathologic - Abstract
Massive spontaneous hemothorax is a very uncommon, life-threatening situation. Acute dissection and ruptured aorta can be one of the differential diagnoses, but usually the clinical feature is completely different, and very few patients have survived this event and received medical attention. Among other causes of spontaneous bleeding, some are extremely rare, demanding precise diagnosis and judicial and immediate intervention. We describe a patient who presented with a massive hemothorax. There was no immediately apparent cause. Emergent angiography revealed active bleeding from an extremely unusual source: aneurysmal dilatation of the internal thoracic artery.
- Published
- 1998
30. Etiological factors influencing the development of atrioventricular valve incompetence after heart transplantation
- Author
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G Sahar, Eldad Erez, Tuvia Ben-Gal, Dan Aravot, Bernardo A. Vidne, A. Stamler, and Alik Sagie
- Subjects
Heart transplantation ,Transplantation ,medicine.medical_specialty ,Atrioventricular valve ,Tricuspid valve ,business.industry ,medicine.medical_treatment ,Middle Aged ,Tricuspid Valve Insufficiency ,Surgery ,medicine.anatomical_structure ,Internal medicine ,medicine ,Cardiology ,Etiology ,Heart Transplantation ,Humans ,Transplantation, Homologous ,business ,Follow-Up Studies ,Retrospective Studies - Published
- 1997
31. Surgical results in cardiac patients over the age of 80 years
- Author
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G, Sahar, E, Raanani, A, Sagie, N, Ad, and B A, Vidne
- Subjects
Aged, 80 and over ,Treatment Outcome ,Aortic Valve ,Heart Valve Prosthesis ,Quality of Life ,Humans ,Comorbidity ,Coronary Artery Bypass ,Length of Stay ,Survival Analysis ,Aged ,Follow-Up Studies - Abstract
Improved medical care over the years has increased life expectancy and consequently the number of aged persons suffering from cardiac disease. During the past 3 years, 42 consecutive octogenarians, with an average age of 82.1 years, were evaluated. Thirty patients had coronary artery bypass graft surgery (CABG), 5 had aortic valve replacement (AVR), and 7 had combined CABG-AVR surgery. Among the ischemic patients 70% had suffered from unstable angina pectoris, and an average of 2.78 +/- 1 grafts per patients were performed. The left internal mammary artery was used in 12 patients (32%). Overall mortality was 7.1% (3 patients), while operative mortality was 2.4% (1 patient). Another two patients who expired during the 34 month follow-up period underwent AVR. The average hospitalization period was 10.2, 12 and 17.6 days for patients undergoing CABG, combined CABG-AVR, and AVR alone, respectively. Complications occurred in 10 patients (24%) and included neurologic deficits (in 2 patients), severe wound infection (in 2), cardiac arrhythmia (in 4), renal failure (in 1) and adult respiratory distress syndrome (in 1). The use of the left internal mammary artery was not associated with an increased incidence of complications. The low rate of mortality and major complications and the substantial improvement in quality of life led us to conclude that, when indicated, surgical treatment should be offered to selected elderly individuals who otherwise are in good physical and mental health.
- Published
- 1996
32. A new immunosuppressive protocol for lung transplantation: early promising results
- Author
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Ehud Raanani, D Bendayan, Alexander Kogan, B Orlov, M.R. Kramer, Milton Saute, G Sahar, Bernardo A. Vidne, Marius Berman, Leonid A. Eidelman, and Dan Aravot
- Subjects
Protocol (science) ,Transplantation ,Chemotherapy ,medicine.medical_specialty ,Time Factors ,Lung ,business.industry ,medicine.medical_treatment ,Mycophenolic Acid ,Tacrolimus ,Text mining ,medicine.anatomical_structure ,medicine ,Humans ,Lung transplantation ,Drug Therapy, Combination ,Surgery ,business ,Intensive care medicine ,Immunosuppressive Agents ,Follow-Up Studies ,Lung Transplantation ,Retrospective Studies - Published
- 2003
- Full Text
- View/download PDF
33. Outcome of marginal donors in heart transplantation
- Author
-
Dan Aravot, G Sahar, Bernardo A. Vidne, Tuvia Ben-Gal, Yaron Shapira, Georgios P. Georghiou, Marius Berman, Alexander Kogan, Alik Sagie, and R Michowitch
- Subjects
Adult ,Male ,Inotrope ,Brain Death ,medicine.medical_specialty ,medicine.medical_treatment ,Treatment outcome ,Organ transplantation ,medicine ,Humans ,Intensive care medicine ,Critical condition ,Heart transplantation ,Transplantation ,Lung ,business.industry ,Limiting ,Middle Aged ,Tissue Donors ,Treatment Outcome ,medicine.anatomical_structure ,Heart Transplantation ,Female ,Surgery ,business - Abstract
THE NUMBER of patients awaiting organ transplantation has progressively increased over the last decade. The progression of the discrepancy between suitable donors and potential recipients on waiting lists will have the consequence of an increasing use of organs from marginal donors. Organs that would have been thought unsuitable for transplantation not so long ago are currently used for transplantation. Advanced age, prolonged CPR, heavy inotropic support, or coronary lesions define marginal donors. Marginal recipients are advanced in age, have other diseases as limiting factors, or have been hospitalized in critical condition. From a total number of 100 transplantations (heart and/or lung) performed in our center, we present three cases in which ethical difficulties arose.
- Published
- 2003
- Full Text
- View/download PDF
34. Organ transplantation statistics in different countries: Internet review
- Author
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G Sahar, G Godovic, J Cohen, Marius Berman, Dan Aravot, Ehud Raanani, Alexander Kogan, B Orlov, Bernardo A. Vidne, and Pierre Singer
- Subjects
medicine.medical_specialty ,education ,MEDLINE ,Specialty ,Organ transplantation ,World Wide Web ,medicine ,Humans ,Statistical analysis ,Kidney transplantation ,Internet ,Transplantation ,business.industry ,Australia ,Organ Transplantation ,South America ,medicine.disease ,United States ,Surgery ,Europe ,surgical procedures, operative ,The Internet ,business ,New Zealand - Abstract
TYPE THE WORDS “kidney transplantation” or “heart transplantation” or a similar combination into one of the more robust search engines on the World Wide Web and you will retrieve hundreds of thousands of different sites that refer to the specialty in some manner. Most international and national transplant associations have web sites, and a world of news, research, clinical cases, and statistical data are available on-line over the Internet. The aim of this study was to search international and national transplantation databases
- Published
- 2003
- Full Text
- View/download PDF
35. Israeli participation in periodical transplantation literature
- Author
-
J Cohen, Marius Berman, Alexander Kogan, G Sahar, Ehud Raanani, Dan Aravot, B Orlov, Bernardo A. Vidne, and Pierre Singer
- Subjects
Transplantation ,medicine.medical_specialty ,Economic growth ,business.industry ,Population size ,Publications ,International exchange ,Organ transplantation ,Surgery ,Humans ,Medicine ,Israel ,Periodicals as Topic ,Organ transplantation in Israel ,Medical science ,business - Abstract
THE OBJECTIVE of all scientific publications regardless of their type or size, is the international exchange of knowledge and new ideas. The United States, Germany, United Kingdom, Japan, and European countries are the leading contributors to medical science. In particular, the contribution of individual countries may depend on factors such as the language spoken and the population size. Organ transplantation in Israel is a therapeutic modality for end-stage organ diseases. The number of transplantations has increased since 1963. In the present study, we evaluated the contributions of Israel and of other nations in the field of organ transplantation according to their population size.
- Published
- 2003
- Full Text
- View/download PDF
36. Cardiac surgery in octogenarians
- Author
-
G, Sahar, E, Raanani, R, Brauner, and B A, Vidne
- Subjects
Aged, 80 and over ,Male ,Time Factors ,Age Factors ,Stroke Volume ,Length of Stay ,Postoperative Complications ,Aortic Valve ,Quality of Life ,Humans ,Female ,Cardiac Surgical Procedures ,Coronary Artery Bypass ,Internal Mammary-Coronary Artery Anastomosis ,Aged ,Follow-Up Studies - Abstract
Age as an important risk factor in surgery has always been debatable. Between January 1991 and December 1992, 35 consecutive octogenarian patients (23 males and 12 females; average age 82.3 years) were retrospectively evaluated. Twenty-five patients had only coronary artery by-pass graft operations (CABG), five had aortic valve replacements (AVR) and five had combined AVR-CABG operations. Twenty-five of the 30 patients (83%) who underwent CABG alone or a combined procedure had suffered from unstable angina. The mean ejection fraction was 40% in this group. An average of 2.8 grafts per patient was performed. The left internal mammary artery (LIMA) was-used in nine patients (30%). The average hospitalization period was 11.5 days. Operative mortality (within 30 days) was zero. Patients who underwent AVR only were hospitalized for an average of 17.6 days and there were two cases (6%) of mortality in this group. All patients who underwent AVR and CABG were discharged within 14 days. Overall complications occurred in nine patients (25.7%); cardiac arrythmias, (4) neurological deficits (2), severe wound infections (2), and adult respiratory distress syndrome (1). The use of the LIMA was not associated with an increased incidence of bleeding or sternal infection. The low rates of mortality and major complications lead us to conclude that, when indicated, surgical treatment including the use of LIMA in selected cases, should be offered to this group of patients, even in the presence of moderate LV dysfunction.
- Published
- 1994
37. Self-assessed quality of life in patients evaluated for heart transplantation: correlation with prognostic indicators
- Author
-
M Berman, G Sahar, Dan Aravot, Tuvia Ben-Gal, M Mansharov, Nili Zafrir, Bernardo A. Vidne, and Alexander Battler
- Subjects
Self-Assessment ,medicine.medical_specialty ,Heart disease ,medicine.medical_treatment ,Correlation ,Oxygen Consumption ,Quality of life ,Surveys and Questionnaires ,Internal medicine ,Humans ,Ventricular Function ,Medicine ,In patient ,Intensive care medicine ,Retrospective Studies ,Heart Failure ,Heart transplantation ,Transplantation ,business.industry ,medicine.disease ,Predictive factor ,Survival Rate ,Heart failure ,Quality of Life ,Heart Transplantation ,Surgery ,business - Published
- 2001
- Full Text
- View/download PDF
38. Clinical characteristics of patients awaiting heart transplantation at Rabin Medical Center in 1997 and 1999
- Author
-
Alexander Battler, Bernardo A. Vidne, M Berman, Nili Zafrir, G Sahar, Tuvia Ben-Gal, Dan Aravot, and M Mansharov
- Subjects
Heart transplantation ,Transplantation ,medicine.medical_specialty ,Time Factors ,Tissue and Organ Procurement ,Waiting Lists ,business.industry ,medicine.medical_treatment ,Coronary Disease ,Middle Aged ,Surgery ,Clinical investigation ,Heart Transplantation ,Humans ,Medicine ,Center (algebra and category theory) ,Coronary Artery Bypass ,Israel ,business - Published
- 2001
- Full Text
- View/download PDF
39. Functional status and quality of life of heart-lung transplant recipients
- Author
-
Bernardo A. Vidne, Milton Saute, Tuvia Ben-Gal, Dan Aravot, M.R. Kramer, Alik Sagie, D Ben Dayan, H Blau, G Sahar, Marius Berman, and Leonid A. Eidelman
- Subjects
Adult ,Male ,Grande bretagne ,medicine.medical_specialty ,Adolescent ,Heart-Lung Transplantation ,medicine.medical_treatment ,Quality of life ,Internal medicine ,medicine ,Humans ,Marriage ,Royaume uni ,Transplantation ,Lung ,business.industry ,Middle Aged ,Surgery ,medicine.anatomical_structure ,Heart–lung transplant ,Circulatory system ,Quality of Life ,Functional status ,business - Published
- 2001
- Full Text
- View/download PDF
40. Correlation between maximal exercise capacity and right-ventricular function in candidates for heart transplantation
- Author
-
G Sahar, Nili Zafrir, Tuvia Ben-Gal, Dan Aravot, Marius Berman, and A. Pinchas
- Subjects
Adult ,Male ,medicine.medical_specialty ,Waiting Lists ,medicine.medical_treatment ,Ventriculo derecho ,Ventricular Function, Left ,Electrocardiography ,Oxygen Consumption ,Internal medicine ,medicine ,Humans ,Exercise ,Heart Failure ,Heart transplantation ,Transplantation ,Ejection fraction ,Ventricular function ,business.industry ,Exercise Test ,Ventricular Function, Right ,Cardiology ,Heart Transplantation ,Female ,Surgery ,Maximal exercise ,business - Published
- 2000
- Full Text
- View/download PDF
41. Employment is a misleading indicator for successful outcome after heart transplantation
- Author
-
Bernardo A. Vidne, M Lerman, Alik Sagie, Tuvia Ben-Gal, Alon Stamler, Eldad Erez, Dan Aravot, and G Sahar
- Subjects
Employment ,Male ,Heart transplantation ,Transplantation ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Heart ,Physical exercise ,Middle Aged ,Survival Analysis ,Outcome (game theory) ,Treatment Outcome ,Quality of life ,medicine ,Physical therapy ,Heart Transplantation ,Humans ,Female ,Surgery ,Intensive care medicine ,business - Published
- 1999
- Full Text
- View/download PDF
42. [Untitled]
- Author
-
Yael Raviv, D Bendayan, Ilana Bakal, G Sahar, David Shitrit, Anat Amital, Milton Saute, Alexander Kogan, and M.R. Kramer
- Subjects
Pulmonary and Respiratory Medicine ,Transplantation ,Pulmonary surfactant ,business.industry ,Anesthesia ,medicine.medical_treatment ,Medicine ,Lung transplantation ,Surgery ,Cardiology and Cardiovascular Medicine ,business - Published
- 2006
- Full Text
- View/download PDF
43. Beta-2 microglobulin in heart transplanted patients
- Author
-
D. Abramov, Ehud Raanani, Bernardo A. Vidne, Erez Sharoni, Eldad Erez, D.V. Dijk, Dan Aravot, G Sahar, and Arie Erman
- Subjects
Graft Rejection ,Male ,Heart transplantation ,Transplantation ,medicine.medical_specialty ,Chemotherapy ,Beta-2 microglobulin ,business.industry ,medicine.medical_treatment ,Middle Aged ,Ciclosporin ,Gastroenterology ,Internal medicine ,Immunology ,medicine ,Heart Transplantation ,Humans ,Transplantation, Homologous ,Female ,Surgery ,beta 2-Microglobulin ,business ,Biomarkers ,medicine.drug - Published
- 1997
- Full Text
- View/download PDF
44. No Role for Azithromycin Therapy in BOS in Lung Transplant Recipients
- Author
-
Ilana Bakal, Mordechai R. Kramer, Milton Saute, G Sahar, and David Shitrit
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Lung ,business.industry ,medicine.medical_treatment ,Critical Care and Intensive Care Medicine ,Azithromycin ,medicine.anatomical_structure ,Internal medicine ,Medicine ,Lung transplantation ,Cardiology and Cardiovascular Medicine ,business ,medicine.drug - Published
- 2004
- Full Text
- View/download PDF
45. Atrial fibrillation after adult lung transplantation
- Author
-
Bernardo A. Vidne, Alexander Kogan, N Ilgaev, M.R. Kramer, Dan Aravot, Milton Saute, G Sahar, and Marius Berman
- Subjects
Adult ,medicine.medical_specialty ,medicine.medical_treatment ,Amiodarone ,Atrial dysrhythmia ,Postoperative Complications ,Atrial Fibrillation ,Retrospective analysis ,Humans ,Medicine ,Lung transplantation ,Retrospective Studies ,Transplantation ,business.industry ,Atrial fibrillation ,respiratory system ,University hospital ,medicine.disease ,humanities ,respiratory tract diseases ,Surgery ,Cardiothoracic surgery ,business ,Anti-Arrhythmia Agents ,Lung Transplantation - Abstract
ATRIAL fibrillation (AF) is the most common dysrhythmia seen early after major thoracic surgery. Atrial dysrhythmia has been observed in children undergoing lung transplantation, but AF after adult lung transplantation in the early postoperative period has not previously been reported. A Heart and Lung Transplantation Unit in the Department of Cardiothoracic Surgery in a university hospital is the setting for this retrospective analysis.
- Published
- 2003
- Full Text
- View/download PDF
46. Altruism and donation
- Author
-
Alik Sagie, Bernardo A. Vidne, Marius Berman, Dan Aravot, H. Shmuely, G Sahar, Alexander Kogan, Tuvia Ben-Gal, Yaron Shapira, and E. Sahar
- Subjects
Transplantation ,Informed Consent ,Donation ,Humans ,Family ,Surgery ,Organ donation ,Altruism (biology) ,Psychology ,Altruism ,Social psychology ,Tissue Donors - Published
- 2003
- Full Text
- View/download PDF
47. First-time status 1 heart transplant candidates: inevitably poor prognosis?
- Author
-
Alexander Kogan, Bernardo A. Vidne, T. Ben Gal, Alon Stamler, Dan Aravot, Georgios P. Georghiou, Marius Berman, and G Sahar
- Subjects
Transplantation ,medicine.medical_specialty ,Poor prognosis ,Time Factors ,Waiting Lists ,business.industry ,Prognosis ,Treatment Outcome ,medicine ,Heart Transplantation ,Humans ,Surgery ,Intensive care medicine ,business - Published
- 2001
- Full Text
- View/download PDF
48. Surgery, PTCA or medical treatment — which is the best modality of treatment in octogenarian patients with coronary artery disease
- Author
-
G. Sahar, N. Ad, E. Raanani, Bernardo A. Vidne, and M. Yanko
- Subjects
Coronary artery disease ,medicine.medical_specialty ,Modality (human–computer interaction) ,Medical treatment ,business.industry ,medicine ,Radiology, Nuclear Medicine and imaging ,Surgery ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,medicine.disease - Published
- 1995
- Full Text
- View/download PDF
49. Planning of Minimum- Time Trajectories for Robot Arms
- Author
-
G. Sahar and John M. Hollerbach
- Subjects
0209 industrial biotechnology ,Engineering ,Mathematical optimization ,02 engineering and technology ,Workspace ,law.invention ,Computer Science::Robotics ,Industrial robot ,020901 industrial engineering & automation ,Artificial Intelligence ,Displacement control ,law ,0202 electrical engineering, electronic engineering, information engineering ,Electrical and Electronic Engineering ,business.industry ,Applied Mathematics ,Mechanical Engineering ,Minimum time ,Control engineering ,Modeling and Simulation ,Robot ,Graph (abstract data type) ,020201 artificial intelligence & image processing ,business ,Actuator ,Robotic arm ,Software - Abstract
The minimum-time path for a robot arm has been a long standing and unsolved problem of considerable interest. We present a general solution to this problem which involves joint-space tessellation, a dynamic time-scaling algorithm, and a graph search. The solution incorporates full dynamics of movement and actuator constraints, and can easily be extended for joint limits and workspace obstacles. It was found that optimal paths tend to be nearly straight lines in joint space. We discuss implementation difficulties due to the tessellation and to combinatorial proliferation of paths.
- Published
- 1986
- Full Text
- View/download PDF
50. Wrist-Partitioned, Inverse Kinematic Accelerations and Manipulator Dynamics
- Author
-
G. Sahar and John M. Hollerbach
- Subjects
Kinematic chain ,Engineering ,0209 industrial biotechnology ,321 kinematic structure ,Inertial frame of reference ,Computation ,Inverse ,02 engineering and technology ,Kinematics ,Inverse dynamics ,Computer Science::Robotics ,Acceleration ,020901 industrial engineering & automation ,Artificial Intelligence ,Control theory ,0202 electrical engineering, electronic engineering, information engineering ,Electrical and Electronic Engineering ,Astrophysics::Galaxy Astrophysics ,Mathematics ,Inverse kinematics ,business.industry ,Applied Mathematics ,Mechanical Engineering ,Motion control ,Modeling and Simulation ,020201 artificial intelligence & image processing ,business ,Software - Abstract
An efficient algorithm is presented for the calculation of the inverse kinematic accelerations for a six-degree-of-freedom manipulator with a spherical wrist. The inverse kinematic calculation is shown to work synergistically with the inverse dynamic calculation, producing kinematic parameters needed in the recursive Newton-Euler dynamics formulation. Additional savings in the dynamic computation are noted for a class of kinematically well-structured manipulators, such as spherical-wrist arms, and for manipulators with simply structured inertial parameters.
- Published
- 1983
- Full Text
- View/download PDF
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