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Three Gram-negative, rod-shaped, oxidase-positive, non-spore-forming, non-motile strains (C130915_07T, C150915_16 and C150915_17) were isolated from lymph nodes of Algerian cows. On the basis of 16S rRNA gene and whole genome similarities, the isolates were almost identical and clearly grouped in the genus Pseudochrobactrum . This allocation was confirmed by the analysis of fatty acids (C19:cyclo, C18 : 1, C18 : 0, C16 : 1 and C16 : 0) and of polar lipids (major components: phosphatidylethanolamine, ornithine-lipids, phosphatidylglycerol, cardiolipin and phosphatidylcholine, plus moderate amounts of phosphatidylmonomethylethanolamine, phosphatidyldimethylethanolamine and other aminolipids). Genomic, physiological and biochemical data differentiated these isolates from previously described Pseudochrobactrum species in DNA relatedness, carbon assimilation pattern and growth temperature range. Thus, these organisms represent a novel species of the genus Pseudochrobactrum , for which the name Pseudochrobactrum algeriensis sp. nov. is proposed (type strain C130915_07T=CECT30232T=LMG 32378T).

In this work we study the production and swapping of non-gaussian multipartite entanglement in a setup containing a parametric amplifier which generates three photons in different modes coupled to three qubits. We prove that the entanglement generated in this setup is of nongaussian nature. We introduce witnesses of genuine tripartite nongaussian entanglement, valid both for mode and qubit entanglement. Moreover, those witnesses show that the entanglement generated among the photons can be swapped to the qubits, and indeed the qubits display nongaussian genuine tripartite entanglement over a wider parameter regime, suggesting that our setup could be a useful tool to extract entanglement generated in higher-order parametric amplification for quantum metrology or quantum computing applications.

Metabolic-associated fatty liver disease (MAFLD) has risen as one of the leading etiologies for hepatocellular carcinoma (HCC). Oncogenes have been suggested to be responsible for the high risk of MAFLD-related HCC. We analyzed the impact of the proto-oncogene c-MYC in the development of human and murine MAFLD and MAFLD-associated HCC.

The plant microbiome is likely to play a key role in the resilience of communities to the global climate change. This research analyses the culturable fungal mycobiota of Brachypodium rupestre across a sharp gradient of disturbance caused by an intense, anthropogenic fire regime. This factor has dramatic consequences for the community composition and diversity of high-altitude grasslands in the Pyrenees. Plants were sampled at six sites, and the fungal assemblages of shoots, rhizomes, and roots were characterized by culture-dependent techniques. Compared to other co-occurring grasses, B. rupestre hosted a poorer mycobiome which consisted of many rare species and a few core species that differed between aerial and belowground tissues. Recurrent burnings did not affect the diversity of the endophyte assemblages, but the percentages of infection of two core species -Omnidemptus graminis and Lachnum sp. -increased significantly. The patterns observed might be explained by (1) the capacity to survive in belowground tissues during winter and rapidly spread to the shoots when the grass starts its spring growth (O. graminis), and (2) the location in belowground tissues and its resistance to stress (Lachnum sp.). Future work should address whether the enhanced taxa have a role in the expansive success of B. rupestre in these anthropized environments.

Subnanometer-sized metal clusters often feature a molecule-like electronic structure, which makes their physical and chemical properties significantly different from those of nanoparticles and bulk material. Considering potential applications, there is a major concern about their thermal stability and susceptibility towards oxidation. Cu clusters of only 5 atoms (Cu5 clusters) are first synthesized in high concentration using a new-generation wet chemical method. Next, it is shown that, contrary to what is currently assumed, Cu5 clusters display nobility, beyond resistance to irreversible oxidation, at a broad range of temperatures and oxygen pressures. The outstanding nobility arises from an unusual reversible oxidation which is observed by in situ X-ray Absorption Spectroscopy and X-ray Photoelectron Spectroscopy on Cu5 clusters deposited onto highly oriented pyrolitic graphite at different oxygen pressures and up to 773 K. This atypical property is explained by a theoretical approach combining different state-of-the-art first principles theories. It reveals the essential role of collective quantum effects in the physical mechanism responsible for the nobility of Cu5 clusters, encompassing a structural ‘breathing’ through concerted Cu–Cu elongations/contractions upon O2 uptake/release, and collective charge transfer as well. A predictive phase diagram of their reversible oxidation states is also delivered, agreeing with the experimental observations. The collective quantum effects responsible of the observed nobility are expected to be general in subanometer-sized metal clusters, pushing this new generation of materials to an upper level.

Sulfur trioxide (SO3) and the hydroxysulfonyl radical (HOSO2) are two key intermediates in the production of sulfuric acid (H2SO4) on Earth's atmosphere, one of the major components of acid rain. Here, the photochemical properties of these species are determined by means of high-level quantum chemical methodologies, and the potential impact of their light-induced reactivity is assessed within the context of the conventional acid rain generation mechanism. Results reveal that the photodissociation of HOSO2 occurs primarily in the stratosphere through the ejection of hydroxyl radicals (•OH) and sulfur dioxide (SO2). This may decrease the production rate of H2SO4 in atmospheric regions with low O2 concentration. In contrast, the photostability of SO3 under stratospheric conditions suggests that its removal efficiency, still poorly understood, is key to assess the H2SO4 formation in the upper atmosphere.

We present results on the digital quantum simulations of beam-splitter and squeezing interactions. The bosonic Hamiltonians are mapped to qubits and then digitalized in order to implement them in the IBM quantum devices. We use error mitigation and postselection to achieve high-fidelity digital quantum simulations of single-mode and two-mode interactions, as evinced - where possible - by full tomography of the resulting states. We achieve fidelities above 90% in the case of single-mode squeezing with low squeezing values and ranging from 60% to 90% for large squeezing and in the more complex two-mode interactions.

Glioblastoma is the most aggressive tumor of the central nervous system, due to its great infiltration capacity. Understanding the mechanisms that regulate the Glioblastoma invasion front is a major challenge with preeminent potential clinical relevances. In the infiltration front, the key features of tumor dynamics relate to biochemical and biomechanical aspects, which result in the extension of cellular protrusions known as tumor microtubes. The coordination of metalloproteases expression, extracellular matrix degradation, and integrin activity emerges as a leading mechanism that facilitates Glioblastoma expansion and infiltration in uncontaminated brain regions. We propose a novel multidisciplinary approach, based on in vivo experiments in Drosophila and mathematical models, that describes the dynamics of active and inactive integrins in relation to matrix metalloprotease concentration and tumor density at the Glioblastoma invasion front. The mathematical model is based on a non-linear system of evolution equations in which the mechanisms leading chemotaxis, haptotaxis, and front dynamics compete with the movement induced by the saturated flux in porous media. This approach is able to capture the relative influences of the involved agents and reproduce the formation of patterns, which drive tumor front evolution. These patterns have the value of providing biomarker information that is related to the direction of the dynamical evolution of the front and based on static measures of proteins in several tumor samples. Furthermore, we consider in our model biomechanical elements, like the tissue porosity, as indicators of the healthy tissue resistance to tumor progression.

In this article, we reexamine the derivation of the dynamical equations of the Ashtekar-Olmedo-Singh black hole model in order to determine whether it is possible to construct a Hamiltonian formalism where the parameters that regulate the introduction of quantum geometry effects are treated as true constants of motion. After arguing that these parameters should capture contributions from two distinct sectors of the phase space that had been considered independent in previous analyses in the literature, we proceed to obtain the corresponding equations of motion and analyze the consequences of this more general choice. We restrict our discussion exclusively to these dynamical issues. We also investigate whether the proposed procedure can be reconciled with the results of Ashtekar, Olmedo, and Singh, at least in some appropriate limit.

Using quantum systems to efficiently solve quantum chemistry problems is one of the long-sought applications of near-future quantum technologies. In a recent work [J. Argüello-Luengo, Nature (London) 574, 215 (2019)NATUAS0028-083610.1038/s41586-019-1614-4], ultracold fermionic atoms have been proposed for this purpose by showing us how to simulate in an analog way the quantum chemistry Hamiltonian projected in a lattice basis set. Here, we continue exploring this path and go beyond these results in several ways. First, we numerically benchmark the working conditions of the analog simulator and find less demanding experimental setups where chemistry-like behavior in three dimensions can still be observed. We also provide a deeper understanding of the errors of the simulation appearing due to discretization and finite-size effects and provide a way to mitigate them. Finally, we benchmark the simulator characterizing the behavior of two-electron atoms (He) and molecules (HeH+) beyond the example considered in the original work.

Hydroxysulfinyl radical (HOSO) is important due to its involvement in climate geoengineering upon SO2 injection and generation of the highly hygroscopic H2SO4. Its photochemical behavior in the upper atmosphere is, however, uncertain. Here we present the ultraviolet-visible photochemistry and photodynamics of this species by simulating the atmospheric conditions with high-level quantum chemistry methods. Photocleavage to HO + SO arises as the major solar-induced channel, with a minor contribution of H + SO2 photoproducts. The efficient generation of SO is relevant due to its reactivity with O3 and the consequent depletion of ozone in the stratosphere.

The generation of photons from the vacuum by means of the movement of a mirror is known as the dynamical Casimir effect (DCE). In general, this phenomenon is effectively described by a field with time-dependent boundary conditions. Alternatively, we introduce a microscopic model of the DCE capable of capturing the essential features of the effect with no time-dependent boundary conditions. Besides the field, such a model comprises a subsystem representing the mirror's internal structure. In this work, we study one of the most straightforward mirror systems: a qubit moving in a cavity and coupled to one of the bosonic modes. We find that under certain conditions on the qubit's movement that do not depend on its physical properties, a large number of photons may be generated without changing the qubit state, as should be expected for a microscopic model of the mirror.

FF-ATP synthase (ATP synthase) is a central membrane protein that synthetizes most of the ATP in the cell through a rotational movement driven by a proton gradient across the hosting membrane. In mitochondria, ATP synthases can form dimers through specific interactions between some subunits of the protein. The dimeric form of ATP synthase provides the protein with a spontaneous curvature that sustain their arrangement at the rim of the high-curvature edges of mitochondrial membrane (cristae). Also, a direct interaction with cardiolipin, a lipid present in the inner mitochondrial membrane, induces the dimerization of ATP synthase molecules along cristae. The deletion of those biochemical interactions abolishes the protein dimerization producing an altered mitochondrial function and morphology. Mechanically, membrane bending is one of the key deformation modes by which mitochondrial membranes can be shaped. In particular, bending rigidity and spontaneous curvature are important physical factors for membrane remodelling. Here, we discuss a complementary mechanism whereby the rotatory movement of the ATP synthase might modify the mechanical properties of lipid bilayers and contribute to the formation and regulation of the membrane invaginations.

The nuclear RNA-binding protein TDP-43 forms abnormal cytoplasmic aggregates in the brains of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) patients and several molecular mechanisms promoting TDP-43 cytoplasmic mislocalization and aggregation have been proposed, including defects in nucleocytoplasmic transport, stress granules (SG) disassembly and post-translational modifications (PTM). SUMOylation is a PTM which regulates a variety of cellular processes and, similarly to ubiquitination, targets lysine residues. To investigate the possible regulatory effects of SUMOylation on TDP-43 activity and trafficking, we first assessed that TDP-43 is SUMO-conjugated in the nuclear compartment both covalently and non-covalently in the RRM1 domain at the predicted lysine 136 and SUMO-interacting motif (SIM, 106–110 residues), respectively. By using the SUMO-mutant TDP-43 K136R protein, we demonstrated that SUMOylation modifies TDP-43 splicing activity, specifically exon skipping, and influences its sub-cellular localization and recruitment to SG after oxidative stress. When promoting deSUMOylation by SENP1 enzyme over-expression or by treatment with the cell-permeable SENP1 peptide TS-1, the cytoplasmic localization of TDP-43 increased, depending on its SUMOylation. Moreover, deSUMOylation by TS-1 peptide favoured the formation of small cytoplasmic aggregates of the C-terminal TDP-43 fragment p35, still containing the SUMO lysine target 136, but had no effect on the already formed p25 aggregates. Our data suggest that TDP-43 can be post-translationally modified by SUMOylation which may regulate its splicing function and trafficking, indicating a novel and druggable mechanism to explore as its dysregulation may lead to TDP-43 pathological aggregation in ALS and FTD.

Transactive response DNA-binding Protein of 43 kDa (TDP-43) assembles various aggregate forms, including biomolecular condensates or functional and pathological amyloids, with roles in disparate scenarios (e.g., muscle regeneration versus neurodegeneration). The link between condensates and fibrils remains unclear, just as the factors controlling conformational transitions within these aggregate species: Salt- or RNA-induced droplets may evolve into fibrils or remain in the droplet form, suggesting distinct end point species of different aggregation pathways. Using microscopy and NMR methods, we unexpectedly observed in vitro droplet formation in the absence of salts or RNAs and provided visual evidence for fibrillization at the droplet surface/solvent interface but not the droplet interior. Our NMR analyses unambiguously uncovered a distinct amyloid conformation in which Phe-Gly motifs are key elements of the reconstituted fibril form, suggesting a pivotal role for these residues in creating the fibril core. This contrasts the minor participation of Phe-Gly motifs in initiation of the droplet form. Our results point to an intrinsic (i.e., non-induced) aggregation pathway that may exist over a broad range of conditions and illustrate structural features that distinguishes between aggregate forms.

Benchmarking numerical methods in quantum chemistry is one of the key opportunities that quantum simulators can offer. Here, we propose an analog simulator for discrete two-dimensional quantum chemistry models based on cold atoms in optical lattices. We first analyze how to simulate simple models, such as the discrete versions of H and H+2, using a single fermionic atom. We then show that a single bosonic atom can mediate an effective Coulomb repulsion between two fermions, leading to the analog of molecular hydrogen in two dimensions. We extend this approach to larger systems by introducing as many mediating atoms as fermions, and derive the effective repulsion law. In all cases, we analyze how the continuous limit is approached for increasing optical lattice sizes.

Interocular differences in image blur can cause processing speed differences that lead to dramatic misperceptions of the distance and three-dimensional direction of moving objects. This recently discovered illusion—the reverse Pulfrich effect—is caused by optical conditions induced by monovision, a common correction for presbyopia. Fortunately, anti-Pulfrich monovision corrections, which darken the blurring lens, can eliminate the illusion for many viewing conditions. However, the reverse Pulfrich effect and the efficacy of anti-Pulfrich corrections have been demonstrated only with trial lenses. This situation should be addressed, for clinical and scientific reasons. First, it is important to replicate these effects with contact lenses, the most common method for delivering monovision. Second, trial lenses of different powers, unlike contacts, can cause large magnification differences between the eyes. To confidently attribute the reverse Pulfrich effect to interocular optical blur differences, and to ensure that previously reported effect sizes are reliable, one must control for magnification. Here, in a within-observer study with five separate experiments, we demonstrate that (1) contact lenses and trial lenses induce indistinguishable reverse Pulfrich effects, (2) anti-Pulfrich corrections are equally effective when induced by contact and trial lenses, and (3) magnification differences do not cause or impact the Pulfrich effect.

In this work, we extend the formalism of hybrid loop quantum cosmology for primordial perturbations around a flat, homogeneous, and isotropic universe to the new treatment of Friedmann-Lemaître-Robertson-Walker geometries proposed recently by Dapor and Liegener, based on an alternative regularization of the Hamiltonian constraint. In fact, our discussion is applicable also to other possible regularization schemes for loop quantum cosmology, although we specialize our analysis to the Dapor-Liegener proposal and construct explicitly all involved quantum operators for that case.

In this work, we compute the time-dependent masses that govern the dynamics of scalar and tensor perturbations propagating on an effective flat, homogeneous, and isotropic background within the framework of loop quantum cosmology (LQC), regularized according to the procedure put forward by Dapor and Liegener. To do so, we follow the two main approaches that, in the field of LQC, lead to hyperbolic equations for the perturbations in the ultraviolet sector: the hybrid and dressed metric formalisms. This allows us to compare the masses resulting from both proposals and analyze their positivity in regimes of physical interest: the big bounce and the contracting de Sitter phase in the asymptotic past that is a defining feature of the model under consideration.

We discuss the quantization of vacuum Bianchi I spacetimes in the modified formalism of loop quantum cosmology recently proposed by Dapor and Liegener. This modification is based on a regularization procedure where both the Euclidean and Lorentzian terms of the Hamiltonian are treated independently. Whereas the Euclidean part has already been dealt with in the literature for Bianchi I spacetimes, the Lorentzian one has not yet been represented quantum mechanically. After a brief review of the quantum kinematics and the quantization of the Euclidean sector, we represent the Lorentzian part of the Hamiltonian constraint by an operator according to the factor ordering rules of the Martín-Benito-Mena Marugán-Olmedo prescription. We study the general properties of this quantum operator and the superselection rules derived therefrom, resulting in an action similar to that of the Euclidean operator except that the orientation of the densitized triad is not preserved, a fact which leads to a generic enlargement of the superselection sectors. We conclude with an explanation of the mechanism that prevents this enlargement in the isotropic case and a comment on the effect of alternative prescriptions for the implementation of the improved dynamics.

Spontaneous parametric down-conversion (SPDC) has been a key enabling technology in exploring quantum phenomena and their applications for decades. For instance, traditional SPDC, which splits a high-energy pump photon into two lower-energy photons, is a common way to produce entangled photon pairs. Since the early realizations of SPDC, researchers have thought to generalize it to higher order, e.g., to produce entangled photon triplets. However, directly generating photon triplets through a single SPDC process has remained elusive. Here, using a flux-pumped superconducting parametric cavity, we demonstrate direct three-photon SPDC, with photon triplets generated in a single cavity mode or split between multiple modes. With strong pumping, the states can be quite bright, with flux densities exceeding 60 photons per second per hertz. The observed states are strongly non-Gaussian, which has important implications for potential applications. In the single-mode case, we observe a triangular star-shaped distribution of quadrature voltages, indicative of the long-predicted ¿star state.¿ The observed state shows strong third-order correlations, as expected for a state generated by a cubic Hamiltonian. By pumping at the sum frequency of multiple modes, we observe strong three-body correlations between multiple modes, strikingly, in the absence of second-order correlations. We further analyze the third-order correlations under mode transformations by the symplectic symmetry group, showing that the observed transformation properties serve to ¿fingerprint¿ the specific cubic Hamiltonian that generates them. The observed non-Gaussian, third-order correlations represent an important step forward in quantum optics and may have a strong impact on quantum communication with microwave fields as well as continuous-variable quantum computation.

We show that the states generated by a three-mode spontaneous parametric down-conversion (SPDC) interaction Hamiltonian possess tripartite entanglement of a different nature to other paradigmatic three-mode entangled states generated by the combination of two-mode SPDC interactions. While two-mode SPDC generates Gaussian states whose entanglement can be characterized by standard criteria based on two-mode quantum correlations, these criteria fail to capture the entanglement generated by three-mode SPDC. We use criteria built from three-mode correlation functions to show that the class of states recently generated in a superconducting-circuit implementation of three-mode SPDC ideally have tripartite entanglement, contrary to recent claims in the literature. These criteria are suitable for triple SPDC but we show that they fail to detect tripartite entanglement in other states which are known to possess it, which illustrates the existence of two fundamentally different notions of tripartite entanglement in three-mode continuous-variable systems.

In principe, general relativity seems to allow the existence of closed timelike curves (CTC). However, when quantum effects are considered, it is likely that their existence is prevented by some kind of chronological protection mechanism, as Hawking conjectured. Confirming or refuting the conjecture would require a full quantum theory of gravity. Meanwhile, the use of simulations could shed some light on this issue. We propose simulations of CTCs in a quantum system as well as in a classical one. In the quantum simulation, some restrictions appear that are not present in the classical setup, which could be interpreted as an analogue of a chronology protection mechanism.

Adenovirus minor coat protein VI contains a membrane-disrupting peptide that is inactive when VI is bound to hexon trimers. Protein VI must be released during entry to ensure endosome escape. Hexon:VI stoichiometry has been uncertain, and only fragments of VI have been identified in the virion structure. Recent findings suggest an unexpected relationship between VI and the major core protein, VII. According to the high-resolution structure of the mature virion, VI and VII may compete for the same binding site in hexon; and noninfectious human adenovirus type 5 particles assembled in the absence of VII (Ad5-VII-) are deficient in proteolytic maturation of protein VI and endosome escape. Here we show that Ad5-VII- particles are trapped in the endosome because they fail to increase VI exposure during entry. This failure was not due to increased particle stability, because capsid disruption happened at lower thermal or mechanical stress in Ad5-VII- compared to wild-type (Ad5-wt) particles. Cryoelectron microscopy difference maps indicated that VII can occupy the same binding pocket as VI in all hexon monomers, strongly arguing for binding competition. In the Ad5-VII- map, density corresponding to the immature amino-terminal region of VI indicates that in the absence of VII the lytic peptide is trapped inside the hexon cavity, and clarifies the hexon:VI stoichiometry conundrum. We propose a model where dynamic competition between proteins VI and VII for hexon binding facilitates the complete maturation of VI, and is responsible for releasing the lytic protein from the hexon cavity during entry and stepwise uncoating

We find solutions of the Dirac equation in curved spacetime. In particular, we consider 1+1 dimensional sections of several exotic metrics: the Alcubierre metric, which describes a scenario that allows faster-than-light velocity; the Gödel metric, which describes a universe containing closed timelike curves; and the Kerr metric, which corresponds to the metric of a rotating pointlike source, for instance a rotating black hole. Moreover, we also show that the techniques that we use in these cases can be extended to nonstatic metrics.

We explore the interplay between acceleration radiation and the dynamical Casimir effect in the field of superconducting quantum technologies, analyzing the generation of entanglement between two qubits by means of the dynamical Casimir effect in several states of qubit motion. We show that the correlated absorption and emission of photons are crucial for entanglement, which in some cases can be linked to the notion of simultaneity in special relativity.

The synthesis of the ZSM-5 and beta zeolites in their nanosized form has been achieved by using simple alkyl-substituted mono-cationic cyclic ammonium cations as OSDA molecules. The particular combination of a cyclic fragment and a short linear alkyl-chain group (preferentially C) within the monocationic OSDA molecules allows directing the crystallization of nanosized zeolites with excellent solid yields (above 90%). Interestingly, the formation of the nanosized ZSM-5 and beta zeolites mostly depends on the size and nature of the cyclic fragment of the OSDA molecule, resulting in all cases in nanocrystalline solids with homogeneous distributions of particle sizes (∼10-25 nm) and controlled Si/Al molar ratios (∼15-30). The achieved nanosized ZSM-5 and beta zeolites have been extensively characterized by different techniques to study their physico-chemical properties, such as chemical composition, pore accessibility or Brønsted acidity, among others. Moreover, the catalytic properties of the nanosized ZSM-5 and beta zeolites have been evaluated for different chemical reactions, including methanol-to-olefins (MTO) in the case of ZSM-5, and alkylation of benzene with propylene to obtain cumene and oligomerization of light olefins to liquid fuels in the case of beta, observing in all cases improved catalytic activity and product selectivity towards target products when compared to related catalysts.

Changing environments pose a challenge to living organisms. Cells need to gather and process incoming information, adapting to changes in predictable ways. This requires in particular the presence of memory, which allows different internal states to be stored. Biological memory can be stored by switches that retain information on past and present events. Synthetic biologists have implemented a number of memory devices for biological applications, mostly in single cells. It has been shown that the use of multicellular consortia provides interesting advantages to implement biological circuits. Here we show how to build a synthetic biological memory switch using an eukaryotic consortium. We engineered yeast cells that can communicate and retain memory of changes in the extracellular environment. These cells were able to produce and secrete a pheromone and sense a different pheromone following NOT logic. When the two strains were cocultured, they behaved as a double-negative-feedback motif with memory. In addition, we showed that memory can be effectively changed by the use of external inputs. Further optimization of these modules and addition of other cells could lead to new multicellular circuits that exhibit memory over a broad range of biological inputs.

Recolle os traballos presentados no I Congreso Internacional "La Literatura de Emilia Pardo Bazán" organizado pola Casa-Museo Emilia Pardo Bazán e celebrado na Coruña en 2008., Patrocinador: Fundación Caixa Galicia.

Sumario: A publicación recolle as colaboracións presentadas no Simposio sobre a relación de dona Emilia e as súas obras coas artes do espectáculo : o cine ( novelas e contos), a televisión (Os Pazos de Ulloa), e o teatro e a ópera., Patrocinador: Fundación Caixa Galicia.

Patrocina: Fundación Caixa Galicia.

Catálogo de la exposición celebrada en Santiago de Compostela, Sala de Exposiciones, Fundación Caixa Galicia, marzo-mayo 2006 ; Salamanca, Sala de Exposiciones San Eloy, Caja Duero, junio-julio 2006 ; Toledo, Museo de Santa Cruz, septiembre-noviembre 2006 (...y otras), Bibliografía: pp. 199-206.

Sumario: A Casa-Museo Emilia Pardo Bazán, propúxose celebrar anualmente un simposio sobre a vida e a obra de Emilia Pardo Bazán, o primeiro deles realizouse na sede da Rea Academia Galega co obxectivo de estudar o estado da cuestión da investigación pardobazaniana, como punto de partida para os sucesivos simposios.

[EN]This document shows the first results of the work carried out in order to recover and enhance the Northern tract of a traditional pathway called "Camiño dos Arrieiros", a long route that, for about 40 km, connects the town of As Pontes de García Rodríguez with the small port of Bares. The path follows basically the high lands of Faladora and Coriscada heights. This work can be considered as a first step towards the enhancement of a full landscape -that of Ortigueira municipalitycomposed by a number of different spaces, among which one of the more relevant are the high lands of Coriscada. Our aim has not been to show landscape in its current shape, in which past time remains are only a component, but to illustrate it from its temporal dimension, using the processes of change as main argument. In that sense, the humanization of space from Prehistory to present day becomes an essential issue for the discourse, since the area of Coriscada is considered as a typical natural space. Additionally, we have included a brief summary of the legal context regarding this kind of works, and also some methodological concerns in relation to the enhancement of historical routes, from the basis of this specific experience., [ES] En el presente documento presentamos los primeros resultados de los trabajos de recuperación e ilustración del tramo Coriscada Norte del Camiño dos Arrieiros, una parte del camino que en toda su extensión une As Pontes de García Rodríguez con el puerto de Bares a lo largo de las sierras de Faladora y Coriscada. Podemos considerar esta actuación como un paso inicial para la puesta en valor de un paisaje -el del concello de Ortigueiraintegrado por diferentes espacios, uno de los cuales, el de la sierra de Coriscada, es el abarcado por este tramo Coriscada Norte. Nuestro objetivo no ha sido mostrar un paisaje en su dimensión espacial actual, considerando los vestigios del pasado sólo como parte de aquél, sino ilustrarlo desde su dimensión temporal, utilizando como hilo conductor el proceso de cambio, la humanización del medio desde la prehistoria hasta hoy precisamente en un paisaje tan aparentemente natural como es el de la Sierra de Coriscada. Nos ha parecido conveniente acompañar esta presentación de un breve recorrido por la problemática legal y metodológica que entendemos implica la recuperación de caminos históricos, siempre partiendo de nuestra experiencia de trabajo en esta ruta cultural.

[EN]A study of the medicinal and veterinary plants popularly used in El Caurel region (Lugo province, northwest Spain) and their relationships is reported. We obtained data for 85 species belonging to 31 families of vascular plants. Their vernacular names, properties, preparations, mode and popular uses are presented. © 1999 Elsevier Science Ireland Ltd. All rights reserved.

El objetivo de este trabajo es precisar la heterogeneidad genética de cepas de Saccharomyces cerevisiae al curso de la fermentación espontánea de los vinos albariños de una bodega del "Valle del Salnés".