1. Association between dairy product consumption and hyperuricemia in an elderly population with metabolic syndrome
- Author
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Jose Lopez-Miranda, Marian Martín, Karla Alejandra Pérez-Vega, J. A. Martínez, Naomi Cano-Ibáñez, PREDIMED-Plus Investigators, Jacqueline Álvarez-Pérez, Ana Garcia Arellano, Rosa Bernal, Ángel M. Alonso-Gómez, Nancy Babio, Miguel Ángel Martínez-González, Itziar Abete, José Lapetra, Dora Romaguera, Nerea Becerra-Tomás, José Manuel Santos-Lozano, Emili Corbella, Jessica Vaquero-Luna, María C Altozano Rodado, José L Llisterri Caro, Andrés Díaz-López, Julia Wärnberg, Pilar Matía-Martín, Francisco J Carmona-González, Miguel Ruiz-Canela, María Dolores Zomeño, Estefanía Toledo, Rocío Barragán, Antoni Palau, Manoli García de la Hera, José J. Gaforio, Montse Fitó, Antoni Sureda, Clotilde Vázquez, Rebeca Fernández-Carrión, Josep Vidal, Jesús Vioque, Guillermo Mena-Sánchez, Lidia Daimiel, Dolores Corella, Luis Serra-Majem, Marga Morey, José Carlos Fernández-García, Ramon Estruch, Rosa Casas, Jordi Salas-Salvadó, E. Ros, Albert Goday, Josep A. Tur, and Xavier Pintó
- Subjects
Male ,Endocrinology, Diabetes and Metabolism ,Medicine (miscellaneous) ,030204 cardiovascular system & hematology ,Overweight ,Recommended Dietary Allowances ,0302 clinical medicine ,Cheese ,Risk Factors ,Prevalence ,Hyperuricemia ,Diet, Fat-Restricted ,Cheese, Dairy products, Hyperuricemia, Milk, Yogurt ,Randomized Controlled Trials as Topic ,Metabolic Syndrome ,education.field_of_study ,Nutrition and Dietetics ,Age Factors ,Middle Aged ,Yogurt ,Milk ,Cohort ,Female ,medicine.symptom ,Diet, Healthy ,Cardiology and Cardiovascular Medicine ,Nutritive Value ,Population ,030209 endocrinology & metabolism ,Lower risk ,Risk Assessment ,03 medical and health sciences ,Environmental health ,medicine ,Humans ,Obesity ,Risk factor ,education ,Aged ,business.industry ,nutritional and metabolic diseases ,medicine.disease ,Uric Acid ,Cross-Sectional Studies ,Spain ,Dairy Products ,Metabolic syndrome ,business ,Risk Reduction Behavior ,Biomarkers ,Dairy products - Abstract
Background and aims: The prevalence of hyperuricemia has increased substantially in recent decades. It has been suggested that it is an independent risk factor for weight gain, hypertension, hypertriglyceridemia, metabolic syndrome (MetS), and cardiovascular disease. Results from epidemiological studies conducted in different study populations have suggested that high consumption of dairy products is associated with a lower risk of developing hyperuricemia. However, this association is still unclear. The aim of the present study is to explore the association of the consumption of total dairy products and their subtypes with the risk of hyperuricemia in an elderly Mediterranean population with MetS. Methods and results: Baseline cross-sectional analyses were conducted on 6329 men/women (mean age 65 years) with overweight/obesity and MetS from the PREDIMED-Plus cohort. Dairy consumption was assessed using a food frequency questionnaire. Multivariable-adjusted Cox regressions were fitted to analyze the association of quartiles of consumption of total dairy products and their subtypes with the prevalence of hyperuricemia. Participants in the upper quartile of the consumption of total dairy products (multiadjusted prevalence ratio (PR) = 0.84; 95% CI: 0.75-0.94; P-trend 0.02), low-fat dairy products (PR = 0.79; 95% CI: 0.70-0.89; P-trend
- Published
- 2019