1. Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
- Author
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Lunde, Ketil, Solheim, Svein, Aakhus, Svend, Arnesen, Harald, Abdelnoor, Michael, Egeland, Torstein, Endresen, Knut, Ilebekk, Arnfinn, Mangschau, Arild, Fjeld, Jan G., Smith, Hans Jorgen, Taraldsrud, Eli, Grogaard, Haakon Kiil, Bjornerheim, Reidar, Brekke, Magne, Muller, Carl, Hopp, Einar, Ragnarsson, Asgrimur, Brinchmann, Jan E., and Forgang, Kolbjorn
- Subjects
Heart attack -- Care and treatment ,Bone marrow cells -- Health aspects ,Cells -- Transplantation ,Cells -- Methods - Abstract
A randomized, controlled trial, known as the Autologous Stem-Cell Transplantation in Acute Myocardial Infarction (ASTAMI) study, was conducted to investigate whether intracoronary injection of autologous mononuclear bone marrow (BMC) results in a clinically important improvement in left ventricular function as measured by the left ventricular ejection factor (LVEF). Results showed no effects of intracoronary injection of autologous mononuclear BMC on global left ventricular function.
- Published
- 2006