Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction

Authors :: Lunde, Ketil
Solheim, Svein
Aakhus, Svend
Arnesen, Harald
Abdelnoor, Michael
Egeland, Torstein
Endresen, Knut
Ilebekk, Arnfinn
Mangschau, Arild
Fjeld, Jan G.
Smith, Hans Jorgen
Taraldsrud, Eli
Grogaard, Haakon Kiil
Bjornerheim, Reidar
Brekke, Magne
Muller, Carl
Hopp, Einar
Ragnarsson, Asgrimur
Brinchmann, Jan E.
Forgang, Kolbjorn
Source :: The New England Journal of Medicine. Sept 21, 2006, Vol. 355 Issue 12, p1199, 11 p.
Publication Year :: 2006
Abstract: A randomized, controlled trial, known as the Autologous Stem-Cell Transplantation in Acute Myocardial Infarction (ASTAMI) study, was conducted to investigate whether intracoronary injection of autologous mononuclear bone marrow (BMC) results in a clinically important improvement in left ventricular function as measured by the left ventricular ejection factor (LVEF). Results showed no effects of intracoronary injection of autologous mononuclear BMC on global left ventricular function.

Subjects :: Heart attack -- Care and treatment
Bone marrow cells -- Health aspects
Cells -- Transplantation
Cells -- Methods

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