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1. Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies

Author

Abrahamovych, Orest, Abu-farsakh, Niazy, Afanasieva, Halyna, Akpinar, Hale, Al Kharrat, Houssam, Altintas, Engin, Altwegg, Romain, Andreev, Pavel, Aomatsu, Kazuki, Araki, Hiroshi, Argollo, Marjorie, Ariel, Federico, Armuzzi, Alessandro, Ashida, Toshifumi, Augustyn, Monika, Aumais, Guy, Azum, Martín, Baert, Filip, Balaz, Jozef, Balderramo, Domingo, Begun, Jakob, Berova, Temenuzhka, Billiauws, Lore, Blanco, Antonio, Bortlik, Martin, Bossa, Fabrizio, Bunkova, Elena, Cabello, Mercedes, Cao, Qian, Caprioli, Flavio, Cerqueira, Rute, Chachu, Karen, Chamouard, Patrick, Chen, Chunxiao, Chen, Yan, Chen, Baili, Chen, Dongfeng, Chen, Hong, Chen, Youxiang, Chen, Chou-chen, Cheon, Jaehee, Chen, Minhu, Chiu, Cheng-tang, Choi, Changhwan, Chow, Elizabeth, Cicala, Michele, Cintra, Aderson, Danilkiewicz, Wit, Datsenko, Olena, De Hertogh, Gert, De María, Julio, Del Valle Torrealba Medina, Leyanira, Deliang, Liu, Desreumaux, Pierre, Dewint, Pieter, Ding, Shigang, Doherty, Glen, Draganova, Raina, Dutré, Joris, Duvall, George, Egan, Laurence, Fahed, Julien, Fechner, Lars, Fedurco, Miroslav, Ferhat Celik, Aykut, Fernandez, Juan, Filip, Rafal, Fishman, Sigal, Flores, Cristina, Fogel, Ronald, Fowler, Sharyle, Francesconi, Carlos, Fujii, Toshimitsu, Fujiya, Mikihiro, Fukata, Masayuki, Fukuhara, Seiichiro, Furumoto, Yohei, G.Kiss, Gyula, Gachowski, Waldemar, Gao, Xiang, Gasbarrini, Antonio, Gawdis-wojnarska, Beata, Gaya, Daniel, Geccherle, Andrea, Gilletta De Saint Joseph, Cyrielle, Gimenez, Edgardo, Gionchetti, Paolo, Goldin, Eran, Golovchenko, Oleksandr, Gonciarz, Maciej, Gonen, Can, Gonzales, Chad, Gonzalez, Raquel, Gonzalez Segura, Gaston Julian, Gridnyev, Oleksiy, Gu, Fang, Gupta, Nitin, Gyokeres, Tibor, Haines, Melissa, Hebuterne, Xavier, Hedin, Charlotte, Hellstrom, Per, Hilmi, Ida Normiha, Hirai, Fumihito, Hisabe, Takashi, Hlavaty, Tibor, Hoentjen, Frank, Holtmann, Gerald, Horiki, Noriyuki, Horny, Ivo, Horvat, Gyula, Horvath, Frantisek, Hoshi, Namiko, Hosomi, Shuhei, Hospodarskyy, Ihor, Hou, Xiaohua, Hrdlicka, Ludek, Hu, Naizhong, Huang, Vivian, Huang, Caibin, Inaba, Tomoki, Ishiguro, Yoh, Ishihara, Shunji, Ishikawa, Takeshi, Iskandar, Heba, Israeli, Eran, Itaba, Soichi, Ivanishyn, Olha, Izbéki, Ferenc, Jain, Animesh, Jairath, Vipul, Jang, Byung Ik, Jiang, Chunmeng, Jones, Michael, Kagaya, Takashi, Kalimullina, Dilara, Karakina, Marina, Karatas, Ali, Kashimura, Hiroshi, Keret, Dan, Khovaeva, Yaroslava, Kierkus, Jaroslaw, Kim, Taeoh, Kim, Youngho, Kim, Hyo Jong, Klaus, Jochen, Kleczkowski, Dariusz, Klopocka, Maria, Kobayashi, Taku, Kobielusz-gembala, Iwona, Kojima, Yuichiro, Koo, Ja Seol, Kopon, Adam, Kopp, James, Koyama, Fumikazu, Koynarski, Vasil, Kravchenko, Tetiana, Kudo, Masatoshi, Kusunoki, Ryusaku, Kwon, Kwangan, Laclav, Martin, Lago, Paula, Laharie, David, Lasa, Juan, Lateef, Syed, Latinovic Radakovic, Tatjana, Lee, Kang Moon, Leszczyszyn, Jaroslaw, Li, Yan, Liu, Mei, Liu, Eashen, Lobaton Ortega, Triana, Lopatin, Denis, Lopes, Susana, Lovric Jovanovic, Mileva, Lubini, Marcio, Lukas, Milan, Maaser, Christian, Machytka, Evzen, Maemoto, Atsuo, Magro, Fernando, Marcet, Jorge, Marini, Eduardo, Marusawa, Hiroyuki, Matous, Jan, Matsumoto, Takayuki, Mendu, Shoba, Miao, Yinglei, Mihaly, Emese, Miheller, Pal, Ministro, Paula, Miyabayashi, Hideharu, Mohl, Wolfgang, Molnar, Martin, Moore, Gregory, Moran Faienzo, Gabriela, Morral, Eugeni Domenech, Motoya, Satoshi, Murali, Narayanachar, Mustaffa, Nazri Mohamad, Naem, Mohamed, Nakai, Katsuhiko, Nakajima, Koichi, Nakamoto, Yasunari, Nakamura, Masanao, Nancey, Stephane, Navaneethan, Udayakumar, Nawawi, Khairul Najmi Muhammad, Ninomiya, Tomoyuki, Novak, Janos, Oki, Motoji, Oliveira Santana, Genoile, Onizawa, Michio, Ono, Yohei, Osada, Taro, Osipenko, Marina, Owczarek, Danuta, Parente, Jose Miguel, Patel, Kamal, Patel, Bhaktasharan, Pedersen, Peder, Petroniene, Rima, Petrov, Asen, Petrova, Elina, Piquet, Marie-astrid, Pokrotnieks, Juris, Poroshina, Elena, Portela, Francisco, Pruthi, Jatinder S., Prystupa, Lyudmila, Pukitis, Aldis, Qiu, Yun, Rafalsky, Vladimir, Rainis, Tova, Ramos Junior, Odery, Rashid, Mohammed, Rayyan, Yasser, Reshetko, Olga, Ribeiro, Tarsila, Rivero, Montserrat, Roblin, Xavier, Romatowski, Jacek, Rowbotham, David, Ruffinengo, Orlando Enrique, Rydzewska-wyszkowska, Grazyna, Sablin, Oleg, Sai, Souken, Saibeni, Simone, Said, Rosaida Hj. Md., Sakuraba, Hirotake, Samaan, Mark, Sandborn, William, Saruta, Masayuki, Sauk, Jenny, Savarino, Edoardo Vincenzo, Schultz, Michael, Schulze, Joerg, Sedghi, Shahriar, Seidler, Ursula, Seksik, Philippe, Senturk, Omer, Shelton, Edward, Shimizu, Masahito, Shin, Sungjae, Shukla, Richa, Sigal, Michael, Silva Junior, Roberto, Simoes Neto, Joaquim, Siroky Jr., Milan, Smajstrla, Vit, Smid, Vaclav, Smiley, Sarah, Soledad Brunatto, Luciana, Stanislavchuk, Mykola, Stokesberry, David, Stone, Christian, Suiter, Daniel, Suzuki, Takayoshi, Svorcan, Petar, Takagi, Sho, Takagi, Tomohisa, Takamura, Masaaki, Takayama, Tetsuji, Takeuchi, Ken, Tanaka, Akihito, Tanaka, Hiroki, Tanash, Omar, Tang, Wen, Tankova, Ludmila, Teixeira Campos, Luciana, Thin, Lena, Tkachev, Alexander, Tolmanis, Ivars, Tsarynna, Nataliia, Tsonev, Nikolay, Tulassay, Zsolt, Ueo, Tetsuya, Unal, Nalan, Valuyskikh, Ekaterina, Van Dop, Willemijn, Vasilevskaya, Olga, Venugopal, Kannan, Verstockt, Bram, Viamonte, Manuel, Vyshyvanyuk, Vira, Wang, Bangmao, Wang, Xiaoyan, Wang, Jiangbin, Wang, Yufang, Wei, Shu-chen, Weisshof, Roni, Wisam, Sbeit, Wojcik, Katarzyna, Yakovlev, Alexey, Yasuda, Hiroshi, Ye, Byongduk, Yen, Hsu-heng, Yilmaz, Hasan, Yokoyama, Yoko, Yoon, Hyuk, Yoshida, Takeshi, Yurkiv, Andriy, Zaha, Osamu, Zaltman, Cyrla, Zhan, Qiang, Zhang, Hongjie, Zhang, Shutian, Zhu, Lanxiang, Zou, Duowu, Zou, Xiaoping, Zureikat, Firas, Rubin, David T, Allegretti, Jessica R, Panés, Julián, Shipitofsky, Nicole, Yarandi, Shadi S, Huang, Kuan-Hsiang Gary, Germinaro, Matthew, Wilson, Rebbecca, Zhang, Hongyan, Johanns, Jewel, Feagan, Brian G, Hisamatsu, Tadakazu, Lichtenstein, Gary R, Bressler, Brian, Peyrin-Biroulet, Laurent, Sands, Bruce E, and Dignass, Axel

Published
2025
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2. Surgery for Crohn’s Disease Is Associated With a Dysbiotic Microbiome and Metabolome: Results From Two Prospective Cohorts

Author

Wolf, Douglas C., Hron, Bridget, Hanson, John S., Mohanty, Sanjib P., Fogel, Ronald P., Levy, L. Campbell, Iskandar, Heba N., Fischer, Monika, Cohen, Benjamin, Swaminath, Arun, Kane, Sunanda, McCabe, Robert P., Jr., Yen, Eugene F., Hanauer, Stephen B., Hudesman, David P., Afzali, Anita, Kelly, Colleen, Weber, John R., Mahadevan, Uma, Herfarth, Hans, Katz, Jeffery, Taleban, Sasha, Rubin, David T., Yachyshyn, Bruce, Reynolds, Gorman J., Gerich, Mark, Dryden, Gerald W., Quezada, Sandra, Higgins, Peter D.R., Shmidt, Eugenia, Lewis, James D., Schwartz, Marc B., Flynn, Ann D., Saha, Sumona, Horst, Sara N., Chiorean, Michael, Green, Patrick D., Scherl, Ellen J., Sandler, Robert, Brotherton, Carol, Albenberg, Lindsey, Valentine, John F., Suskind, David, Meyer, Andrea, Compher, Charlene W., Bewtra, Meenakshi, Kaur, Manreet, Dassopoulos, Themistocles, Snapper, Scott B., Korzenik, Joshua R., Bohm, Matthew, Raffals, Laura, Beniwal-Patel, Poonam, Hudesman, David, Russ, Kirk, Brook, Loren, Pekow, Joel, Cross, Raymond, Wong, Uni, Bishu, Shrinivas, Duerr, Richard, Caldera, Freddy, Scoville, Elizabeth, Deepak, Parakkal, Ciorba, Matthew, Daniel, Scott G., Li, Hongzhe, Hao, Fuhua, Patterson, Andrew D., Hecht, Aaron L., Brensinger, Colleen M., Wu, Gary D., and Bittinger, Kyle

Published
2024
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3. Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study

Author

Abrahamovych, Orest, Afanasieva, Halyna, Aitova, Lilia, Altintas, Engin, Altwegg, Romain, Andreev, Pavel, Aomatsu, Kazuki, Augustyn, Monika, Balestrieri, Paola, Begun, Jakob, Brunatto, Luciana, Bulgheroni, Diego, Bunkova, Elena, Cabello, Mercedes, Cao, Qian, Caprioli, Flavio, Cerqueira, Rute, Chen, Baili, Chen, Chou-Chen, Chen, Chou-Pin, Chiu, Cheng-Tang, Choi, Chang Hwan, Cicala, Michele, Datsenko, Olena, Dewint, Pieter, Domenech, Eugeni, Dutré, Joris, Duvall, George, Fernandez, Juan, Filip, Rafal, Fogel, Ronald, Fowler, Sharyle, Fujii, Toshimitsu, Fukata, Masayuki, Furumoto, Yohei, Gasbarrini, Antonio, Gawdis-Wojnarska, Beata, Gilletta, Cyrielle, Gionchetti, Paolo, Goldin, Eran, Golovchenko, Oleksandr, Gonciarz, Maciej, Gonen, Can, Segura, Gaston Gonzalez, Gridnyev, Oleksii, Gyokeres, Tibor, Hébuterne, Xavier, Hedin, Charlotte, Hellström, Per, Hilmi, Ida Normiha, Horný, Ivo, Horvat, Gyula, Hoshi, Namiko, Hrdlicka, Ludek, Ishihara, Shunji, Ivanishyn, Olha, Jang, Byung Ik, Junior, Odery, Kagaya, Takashi, Kanmura, Shuji, Karakina, Marina, Katsuhiko, Nakai, Kierkus, Jaroslaw, Kim, Hyo Jong, Kim, Tae-Oh, Kim, Young-Ho, Kiss, Gyula G., Klaus, Jochen, Kleczkowski, Dariusz, Klopocka, Maria, Kobayashi, Taku, Kobielusz-Gembala, Iwona, Koo, Ja Seol, Kopon, Adam, Kravchenko, Tetiana, Kudo, Masatoshi, Kwon, Kwang An, Lago, Paula, Laharie, David, Lawrance, Ian, Leszczyszyn, Jaroslaw, Li, Yan, Lukas, Milan, Maaser, Christian, Maemoto, Atsuo, Marusawa, Hiroyuki, McBride, Matthew, Mendu, Shoba, Miheller, Pal, Miyabayashi, Hideharu, Mohl, Wolfgang, Moore, Gregory, Motoya, Satoshi, Murali, Narayanachar, Naem, Mohammed, Nakajima, Koichi, Nakamoto, Yasunari, Nancey, Stéphane, Neto, Joaquim, Onizawa, Michio, Ono, Yohei, Osada, Taro, Osipenko, Marina, Owczarek, Danuta, Patel, Bhaktasharan, Patel, Kamal, Petrova, Elina, Poroshina, Elena, Portela, Francisco, Prystupa, Lyudmyla, Rivero, Monserrat, Roblin, Xavier, Romatowski, Jacek, Rydzewska, Grazyna, Saibeni, Simone, Sakuraba, Hirotake, Samaan, Mark, Schultz, Michael, Schulze, Joerg, Sedghi, Shahriar, Seidler, Ursula, Shin, Sung Jae, Stanislavchuk, Mykola, Stokesberry, David, Suzuki, Takayoshi, Taguchi, Hiroki, Tankova, Lyudmila, Thin, Lena, Tkachev, Alexander, Torrealba, Leyanira, Tsarynna, Nataliia, Tulassay, Zsolt, Ueo, Tetsuya, Valuyskikh, Ekaterina, Vasilevskaya, Olga, Viamonte, Manuel, Wei, Shu-Chen, Weisshof, Roni, Wojcik, Katarzyna, Ye, Byong Duk, Yen, Hsu-Heng, Yoon, Hyuk, Yoshida, Kosuke, Yurkiv, Andriy, Zaha, Osamu, Zhan, Qiang, Peyrin-Biroulet, Laurent, Allegretti, Jessica R., Rubin, David T., Bressler, Brian, Germinaro, Matthew, Huang, Kuan-Hsiang (Gary), Shipitofsky, Nicole, Zhang, Hongyan, Wilson, Rebbecca, Han, Chenglong, Feagan, Brian G., Sandborn, William J., Panés, Julian, Hisamatsu, Tadakazu, Lichtenstein, Gary R., Sands, Bruce E., and Dignass, Axel

Published
2023
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4. Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study

Author

Adams, Atoya, Andrews, Jane M, Behrend, Clint E, Brown, Gregor J E, Chen Yi Mei, Swee Lin, Coates, Allan G, DiMarino, Anthony J, Ee, Hooi, Elliott, David E, Epstein, Roger M, Feyen, Bryan John, Fogel, Ronald P, Friedenberg, Keith Alan, Gearry, Richard B, Gerdis, Michael S, Goldstein, Michael J, Gupta, Vipin K, Holmes, Robert John, Holtmann, Gerald J, Idarraga, Samuel H, James, George W, King, Tim, Klein, Terry D, Kupfer, Sonia S, Lebwohl, Benjamin, Lowe, Matthew John, Murray, Joseph A, Newton, Eric B, Quinn, Dean, Radin, David M, Ritter, Timothy E, Stacey, Helen Lee, Strout, Cynthia B, Stubbs, Richard S, Thackwray, Susan Lynn, Trivedi, Vivek M, Weber, John R, Wilson, Scott A, Tye-Din, Jason A, Daveson, A James M, Goel, Gautam, Goldstein, Kaela E, Hand, Holly L, Neff, Kristin M, Popp, Alina, Taavela, Juha, Maki, Markku, Isola, Jorma, Williams, Leslie J, Truitt, Kenneth E, and Anderson, Robert P

Published
2023
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5. Long-Term Treatment of Eosinophilic Esophagitis With Budesonide Oral Suspension

Author

Baum, Curtis, Bekal, Pradeep, Chaletsky, David, Chehade, Mirna, Clark, Larry, Jr., Dellon, Evan, Dimmitt, Reed, Dulitz, David, Falk, Gary, Fogel, Ronald, Friedenberg, Keith, Gabbard, Scott, Gentry, Andrew, Gold, Benjamin, Goldstein, Michael, Gupta, Sandeep, Hirano, Ikuo, Hsu-Blatman, Karen, Jayanty, Vikram, Katzka, David, Kunnathur, Vidhya, Lee, John, Leung, John, Markowitz, Jonathan, Menard-Katcher, Calies, Mitlyng, Benjamin, Moussa, Sam E., Mukkada, Vincent, O’Gorman, Molly, Olazagasti, Juan, Ritter, Timothy, Sayej, Wael, Schroeder, Shauna, Smadi, Yamen, Soteres, Daniel, Stathos, Theodore, Vaezi, Michael F., Whitlock, Tom, Wo, John, Younes, Ziad, Zakko, Salam, Dellon, Evan S., Collins, Margaret H., Katzka, David A., Mukkada, Vincent A., Falk, Gary W., Morey, Robin, Goodwin, Bridgett, Eisner, Jessica D., Lan, Lan, Desai, Nirav K., and Williams, James

Published
2022
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6. Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn's disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial

Author

Afzali, Anita, Aitova, Lilia, Aldeguer i Mante, Xavier, Allez, Matthieu, Altorjay, István, Argüelles Arias, Federico, Armuzzi, Alessandro, Augustyn, Monika, Bafutto, Mauro, Barrio, Jesus, Begun, Jakob, Behrend, Clint, Bezemer, Geert, Bonnaud, Guillaume, Brankovic, Marija, Byung, Ik Jang, Calvet Calvo, Xavier, Chachu, Karen, Chebli, Julio Maria Fonseca, Cheon, Jae Hee, Cichoz-Lach, Halina, Clark, Larry, Cummings, Fraser, Dalal, Kunal, Danese, Silvio, De Boer, Nanne, De Lourdes Ferrari, Maria, Désilets, Etienne, Dugalic, Predrag, Duvall, George, Fedorishina, Olga, Filip, Rafal, Flores, Cristina, Fogel, Ronald, Fon, James, Frankel, Michael, Friedenberg, Keith, Fries, Walter, Galina, Vassileva, Gietka, Piotr, Goel, Rishi, Hasselblatt, Peter, Herfarth, Hans, Herszényi, László, Hindryckx, Pieter, Hoentjen, Frank, Horjus Talabur Horje, Carmen, Iduru, Satish, Irving, Peter, Isfort, Robert, Jairath, Vipul, Jones, Michael, Kalimullina, Dilara, Katz, Jeffry, Kaur, Manreet, Khurana, Sunil K, Kim, Joo Sung, Kim, Youngho, Kleczkowski, Dariusz, Knezevic, Slavko, Knoll, Aaron, Korman, Louis Y, Kotzev, Iskren, Kulyapin, Andrey, Lee, Kang Moon, Leemreis, Desiree, Leszczyszyn, Jaroslaw, Limdi, Jimmy, Lissauer, Jack, Loftus, Edward, Malecka-Panas, Ewa, Marshall, John, Mihály, Emese, Milan, Lukas, Monteleone, Giovanni, Nagorni, Aleksandar, Owczarek, Danuta, Palekar, Nichole, Panaccione, Remo, Park, Young Soo, Park, Sang Hyoung, Parra, Rogério, Patai, Árpád, Patel, Kamal, Patel, Bhaktasharan, Pershko, Anatoly, Petrova, Elina, Pineton de Chambrun, Guillaume, Randall, Charles, Riestra Menendez, Sabino, Ritter, Timothy, Rivero, Montserrat, Roblin, Xavier, Rocca, Rodolfo, Romatowski, Jacek, Rydzewska, Grazyna, Saibeni, Simone, Salzberg, Bruce, Sarles, Harry, Saunders, John, Savarino, Edoardo Vincenzo, Serclova, Zuzana, Shchukina, Oksana, Siegel, Jonathan, Soofi, Najm, Sparrow, Miles, Stokesberry, David, Suiter, Daniel, Svorcan, Petar, Tkachev, Alexander, Tsonev, Nikolay, Tünde, Kristóf, Ulbrych, Jan, Vanasek, Tomas, Varga, Márta, Vermeire, Severine, Vicente Lidon, Raquel, Weiss, Michael L, Wesley, Emma, Winstead, Nathaniel, Wojcik, Katarzyna, Wypych, Joanna, Zaltman, Cyrla, Zdena, Zadorova, Sands, Bruce E, Irving, Peter M, Hoops, Timothy, Izanec, James L, Gao, Long-Long, Gasink, Christopher, Greenspan, Andrew, Hanauer, Stephen B, Kuehbacher, Tanja, Lewis, James D, Loftus, Edward V, Jr, Mihaly, Emese, Scherl, Ellen, Shchukina, Oksana B, and Sandborn, William J

Published
2022
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7. Etrolizumab for maintenance therapy in patients with moderately to severely active ulcerative colitis (LAUREL): a randomised, placebo-controlled, double-blind, phase 3 study

Author

Abraham, Philip, Acir Crippa Júnior, Mauro, Aguilar, Humberto, Ahmed, Tasneem, Altorjay, Istvan, Andersen, Vibeke, Arai, Ronen, Arnold, Hays, Ausk, Karlee, Axler, Jeffrey, Ayub, Kamran, Balekuduru, Avinash, Barbalaco Neto, Guerino, Bassan, Isaac, Behm, Brian, Bekal, Pradeep, Bhatia, Shobna, Bod, Barnabas, Brandão Mello, Carlos Eduardo, Brandeburova, Julia, Breedt, Johannes, Bressler, Brian, Chopey, Ivan, Connor, Michael, Corlin, Richard, Cortez Hernandez, Carlos Alejandro, De, Arijit, de Sá Rolim, Alexander, Di Felice Boratto, Sandra, Dixon, Tyler, Dourado Poli, Debora, Dresner, David, Du Vall, George Aaron, Ebert, Matthias, Ehehalt, Robert, Ertan, Atilla, Escarcega Valencia, Ruben, Etzel, Jason, Fallingborg, Jan, Feagan, Brian, Fedurco, Miroslav, Fernandez Castro, Enrique, Ferreira de Almeida Borges, Valéria, Finklestein, Mark, Fischer, Andreas, Fleisher, Mark, Flores Rendon, Angel Ricardo, Fogel, Ronald, Franceschi Junior, Osvaldo, Freedland, Curtis, Gatof, David, Gill, Kanwar, Glerup, Henning, Gokak, Vardaraj, Goldin, Eran, Gomez Jaramillo, Hector Alejandro, Gupta, Nitin, Gurzo, Zoltan, Gyrina, Olga, Habeeb, Mohammed Aejaz, Hanauer, Stephen, Hardi, Robert, Harlan, William, Hemaidan, Ammar, Heyman, Melvin, Hoffmann, Peter, Holderman, William, Holtkamp-Endemann, Frank, Horvat, Gyula, Isaacs, Kim, Israeli, Eran, Jankiel Miszputen, Sender, Jensen, Søren, Johnson, Kenneth, Jones, Jennifer, Junior, Osvaldo, Kadleckova, Barbora, Kalla, Mukesh, Kallo, Zsuzsanna, Karyotakis, Nicholas, Katz, Lior, Katz, Leo, Kaur, Nirmal, Khanna, Reena, Kohout, Pavel, Lakatos, Peter, Larriva de los Reyes, Emmanuel, Lee, Robert, Leman, Bernard, Levchenko, Olena, Levine, Henry, Libanez Bessa Campelo Braga, Lúcia, Loftus, Edward, Lohdanidi, Tetiana, Longman, Randy, Lozano, Josefina, Maaser, Christian, Madi-Szabo, Laszlo, Malluta, Everson Fernando, Marshall, John, Martinez Silva, Francisca, Maynard, Kenneth, Meder, Agnieszka, Mehta, Chetan, Minarik, Peter, Mueller, Joachim, Mukewar, Shrikant, Nagy, Bela, Neiko, Vasyl, Neurath, Markus, Nichol, Brian, Novick, James, Pai, Nitin, Pandak, William, Panigrahi, Sarat, Pape, Ulrich-Frank, Paraná, Raymundo, Parekh, Nimisha, Patel, Bhaktasharan, Pecsi, Gyula, Peralta, Sergio, Pesta, Martin, Peterfai, Eva, Petruzzellis, Carlo, Petryka, Robert, Pica, Roberta, Piniella, Carlos, Pratha, Vijayalakshmi, Prochazka, Vlastimil, Prokopchuk, Sergey, Prystupa, Ludmyla, Puri, Amarender, Rainis, Tova, Ramesh Kumar, Bhashyakarla, Ramos Júnior, Odery, Rishko, Iaroslava, Ritter, Timothy, Robbins, Bryan, Rock, Elizabeth, Rodrigues Borba, Marcelo, Rodriguez, Miguel, Rozciecha, Jerzy, Ruiz Flores, Azalia Yuriria, Rydzewska, Grazyna, Safadi, Rifaat, Saibeni, Simone, Schirbel, Anja, Schmiegel, Wolff, Schnabel, Róbert, Schneider, Herbert, Segui, Armando, Seidelin, Jakob, Seidler, Ursula, Sellin, Joseph, Shafran, Ira, Shah, Saumin, Sheikh, Aasim, Sherman, Alex, Shirin, Haim, Shukla, Akash, Siddiqui, Firdous, Sike, Robert, Sood, Ajit, Stallmach, Andreas, Stanislavchuk, Mykola, Staun, Michael, Stein, Daniel, Steinberg, Alon, Steinhart, Hillary, Stifft, Jonathas, Tandon, Rakesh, Tantry, Vishwanath, Thiwan, Syed, Treiber, Matthias, Ulbrych, Jan, Valentine, John, Vasudeva, Rajeev, Vaughn, Byron, Velasco, Brenda, Vincze, Aron, Volfova, Miroslava, Waterman, Mattitiahu, Weiss, L. Michael, Wiesner, Elise, Williams, Alonzo, Witthoeft, Thomas, Wohlman, Robert, Wright, John, Yamamoto Furusho, Jesus Kazuo, Younes, Ziad, Yousuf, Khurshid, Zborivskyy, Yaroslav, Zeuzem, Stefan, Zhdan, Vyacheslav, Vermeire, Severine, Lakatos, Peter L, Kadva, Alysha, Tyrrell, Helen, Oh, Young S, Tole, Swati, Chai, Akiko, Pulley, Jennifer, Eden, Christopher, Zhang, Wenhui, and Feagan, Brian G

Published
2022
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8. Surgery for Crohn’s Disease Is Associated with a Dysbiotic Microbiome and Metabolome: Results from Two Prospective Cohorts

Author

Lewis, James D., primary, Daniel, Scott G., additional, Li, Hongzhe, additional, Hao, Fuhua, additional, Patterson, Andrew D., additional, Hecht, Aaron, additional, Brensinger, Colleen M., additional, Wu, Gary D., additional, Bittinger, Kyle, additional, Wolf, Douglas C., additional, Hron, Bridget, additional, Hanson, John S., additional, Mohanty, Sanjib P., additional, Fogel, Ronald P., additional, Levy, L. Campbell, additional, Iskandar, Heba N., additional, Fischer, Monika, additional, Cohen, Benjamin, additional, Swaminath, Arun, additional, Kane, Sunanda, additional, McCabe, Robert P., additional, Yen, Eugene F., additional, Hanauer, Stephen B., additional, Hudesman, David P., additional, Afzali, Anita, additional, Kelly, Colleen, additional, Weber, John R., additional, Mahadevan, Uma, additional, Herfarth, Hans, additional, Katz, Jeffery, additional, Taleban, Sasha, additional, Rubin, David T., additional, Yachyshyn, Bruce, additional, Reynolds, Gorman J., additional, Gerich, Mark, additional, Dryden, Gerald W., additional, Quezada, Sandra, additional, Higgins, Peter D.R., additional, Shmidt, Eugenia, additional, Lewis, James D., additional, Schwartz, Marc B., additional, Flynn, Ann D., additional, Saha, Sumona, additional, Horst, Sara N., additional, Chiorean, Michael, additional, Green, Patrick D., additional, Scherl, Ellen J., additional, Sandler, Robert, additional, Brotherton, Carol, additional, Albenberg, Lindsey, additional, Valentine, John F., additional, Suskind, David, additional, Meyer, Andrea, additional, Compher, Charlene W., additional, Bewtra, Meenakshi, additional, Kaur, Manreet, additional, Dassopoulos, Themistocles, additional, Snapper, Scott B., additional, Korzenik, Joshua R., additional, Bohm, Matthew, additional, Raffals, Laura, additional, Beniwal-Patel, Poonam, additional, Hudesman, David, additional, Russ, Kirk, additional, Brook, Loren, additional, Pekow, Joel, additional, Cross, Raymond, additional, Wong, Uni, additional, Bishu, Shrinivas, additional, Duerr, Richard, additional, Caldera, Freddy, additional, Scoville, Elizabeth, additional, Deepak, Parakkal, additional, and Ciorba, Matthew, additional

Published
2024
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9. Filgotinib as induction and maintenance therapy for ulcerative colitis (SELECTION): a phase 2b/3 double-blind, randomised, placebo-controlled trial

Author

Feagan, Brian G, Danese, Silvio, Loftus, Edward V, Jr, Vermeire, Séverine, Schreiber, Stefan, Ritter, Timothy, Fogel, Ronald, Mehta, Rajiv, Nijhawan, Sandeep, Kempiński, Radosław, Filip, Rafał, Hospodarskyy, Ihor, Seidler, Ursula, Seibold, Frank, Beales, Ian L P, Kim, Hyo Jong, McNally, John, Yun, Chohee, Zhao, Sally, Liu, Xiaopeng, Hsueh, Chia-Hsiang, Tasset, Chantal, Besuyen, Robin, Watanabe, Mamoru, Sandborn, William J, Rogler, Gerhard, Hibi, Toshifumi, and Peyrin-Biroulet, Laurent

Published
2021
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10. Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies

Author

Rubin, David T, Allegretti, Jessica R, Panés, Julián, Shipitofsky, Nicole, Yarandi, Shadi S, Huang, Kuan-Hsiang Gary, Germinaro, Matthew, Wilson, Rebbecca, Zhang, Hongyan, Johanns, Jewel, Feagan, Brian G, Hisamatsu, Tadakazu, Lichtenstein, Gary R, Bressler, Brian, Peyrin-Biroulet, Laurent, Sands, Bruce E, Dignass, Axel, Abrahamovych, Orest, Abu-farsakh, Niazy, Afanasieva, Halyna, Akpinar, Hale, Al Kharrat, Houssam, Altintas, Engin, Altwegg, Romain, Andreev, Pavel, Aomatsu, Kazuki, Araki, Hiroshi, Argollo, Marjorie, Ariel, Federico, Armuzzi, Alessandro, Ashida, Toshifumi, Augustyn, Monika, Aumais, Guy, Azum, Martín, Baert, Filip, Balaz, Jozef, Balderramo, Domingo, Begun, Jakob, Berova, Temenuzhka, Billiauws, Lore, Blanco, Antonio, Bortlik, Martin, Bossa, Fabrizio, Bunkova, Elena, Cabello, Mercedes, Cao, Qian, Caprioli, Flavio, Cerqueira, Rute, Chachu, Karen, Chamouard, Patrick, Chen, Chunxiao, Chen, Yan, Chen, Baili, Chen, Dongfeng, Chen, Hong, Chen, Youxiang, Chen, Chou-chen, Cheon, Jaehee, Chen, Minhu, Chiu, Cheng-tang, Choi, Changhwan, Chow, Elizabeth, Cicala, Michele, Cintra, Aderson, Danilkiewicz, Wit, Datsenko, Olena, De Hertogh, Gert, De María, Julio, Del Valle Torrealba Medina, Leyanira, Deliang, Liu, Desreumaux, Pierre, Dewint, Pieter, Ding, Shigang, Doherty, Glen, Draganova, Raina, Dutré, Joris, Duvall, George, Egan, Laurence, Fahed, Julien, Fechner, Lars, Fedurco, Miroslav, Ferhat Celik, Aykut, Fernandez, Juan, Filip, Rafal, Fishman, Sigal, Flores, Cristina, Fogel, Ronald, Fowler, Sharyle, Francesconi, Carlos, Fujii, Toshimitsu, Fujiya, Mikihiro, Fukata, Masayuki, Fukuhara, Seiichiro, Furumoto, Yohei, G.Kiss, Gyula, Gachowski, Waldemar, Gao, Xiang, Gasbarrini, Antonio, Gawdis-wojnarska, Beata, Gaya, Daniel, Geccherle, Andrea, Gilletta De Saint Joseph, Cyrielle, Gimenez, Edgardo, Gionchetti, Paolo, Goldin, Eran, Golovchenko, Oleksandr, Gonciarz, Maciej, Gonen, Can, Gonzales, Chad, Gonzalez, Raquel, Gonzalez Segura, Gaston Julian, Gridnyev, Oleksiy, Gu, Fang, Gupta, Nitin, Gyokeres, Tibor, Haines, Melissa, Hebuterne, Xavier, Hedin, Charlotte, Hellstrom, Per, Hilmi, Ida Normiha, Hirai, Fumihito, Hisabe, Takashi, Hlavaty, Tibor, Hoentjen, Frank, Holtmann, Gerald, Horiki, Noriyuki, Horny, Ivo, Horvat, Gyula, Horvath, Frantisek, Hoshi, Namiko, Hosomi, Shuhei, Hospodarskyy, Ihor, Hou, Xiaohua, Hrdlicka, Ludek, Hu, Naizhong, Huang, Vivian, Huang, Caibin, Inaba, Tomoki, Ishiguro, Yoh, Ishihara, Shunji, Ishikawa, Takeshi, Iskandar, Heba, Israeli, Eran, Itaba, Soichi, Ivanishyn, Olha, Izbéki, Ferenc, Jain, Animesh, Jairath, Vipul, Jang, Byung Ik, Jiang, Chunmeng, Jones, Michael, Kagaya, Takashi, Kalimullina, Dilara, Karakina, Marina, Karatas, Ali, Kashimura, Hiroshi, Keret, Dan, Khovaeva, Yaroslava, Kierkus, Jaroslaw, Kim, Taeoh, Kim, Youngho, Kim, Hyo Jong, Klaus, Jochen, Kleczkowski, Dariusz, Klopocka, Maria, Kobayashi, Taku, Kobielusz-gembala, Iwona, Kojima, Yuichiro, Koo, Ja Seol, Kopon, Adam, Kopp, James, Koyama, Fumikazu, Koynarski, Vasil, Kravchenko, Tetiana, Kudo, Masatoshi, Kusunoki, Ryusaku, Kwon, Kwangan, Laclav, Martin, Lago, Paula, Laharie, David, Lasa, Juan, Lateef, Syed, Latinovic Radakovic, Tatjana, Lee, Kang Moon, Leszczyszyn, Jaroslaw, Li, Yan, Liu, Mei, Liu, Eashen, Lobaton Ortega, Triana, Lopatin, Denis, Lopes, Susana, Lovric Jovanovic, Mileva, Lubini, Marcio, Lukas, Milan, Maaser, Christian, Machytka, Evzen, Maemoto, Atsuo, Magro, Fernando, Marcet, Jorge, Marini, Eduardo, Marusawa, Hiroyuki, Matous, Jan, Matsumoto, Takayuki, Mendu, Shoba, Miao, Yinglei, Mihaly, Emese, Miheller, Pal, Ministro, Paula, Miyabayashi, Hideharu, Mohl, Wolfgang, Molnar, Martin, Moore, Gregory, Moran Faienzo, Gabriela, Morral, Eugeni Domenech, Motoya, Satoshi, Murali, Narayanachar, Mustaffa, Nazri Mohamad, Naem, Mohamed, Nakai, Katsuhiko, Nakajima, Koichi, Nakamoto, Yasunari, Nakamura, Masanao, Nancey, Stephane, Navaneethan, Udayakumar, Nawawi, Khairul Najmi Muhammad, Ninomiya, Tomoyuki, Novak, Janos, Oki, Motoji, Oliveira Santana, Genoile, Onizawa, Michio, Ono, Yohei, Osada, Taro, Osipenko, Marina, Owczarek, Danuta, Parente, Jose Miguel, Patel, Kamal, Patel, Bhaktasharan, Pedersen, Peder, Petroniene, Rima, Petrov, Asen, Petrova, Elina, Piquet, Marie-astrid, Pokrotnieks, Juris, Poroshina, Elena, Portela, Francisco, Pruthi, Jatinder S., Prystupa, Lyudmila, Pukitis, Aldis, Qiu, Yun, Rafalsky, Vladimir, Rainis, Tova, Ramos Junior, Odery, Rashid, Mohammed, Rayyan, Yasser, Reshetko, Olga, Ribeiro, Tarsila, Rivero, Montserrat, Roblin, Xavier, Romatowski, Jacek, Rowbotham, David, Ruffinengo, Orlando Enrique, Rydzewska-wyszkowska, Grazyna, Sablin, Oleg, Sai, Souken, Saibeni, Simone, Said, Rosaida Hj. Md., Sakuraba, Hirotake, Samaan, Mark, Sandborn, William, Saruta, Masayuki, Sauk, Jenny, Savarino, Edoardo Vincenzo, Schultz, Michael, Schulze, Joerg, Sedghi, Shahriar, Seidler, Ursula, Seksik, Philippe, Senturk, Omer, Shelton, Edward, Shimizu, Masahito, Shin, Sungjae, Shukla, Richa, Sigal, Michael, Silva Junior, Roberto, Simoes Neto, Joaquim, Siroky Jr., Milan, Smajstrla, Vit, Smid, Vaclav, Smiley, Sarah, Soledad Brunatto, Luciana, Stanislavchuk, Mykola, Stokesberry, David, Stone, Christian, Suiter, Daniel, Suzuki, Takayoshi, Svorcan, Petar, Takagi, Sho, Takagi, Tomohisa, Takamura, Masaaki, Takayama, Tetsuji, Takeuchi, Ken, Tanaka, Akihito, Tanaka, Hiroki, Tanash, Omar, Tang, Wen, Tankova, Ludmila, Teixeira Campos, Luciana, Thin, Lena, Tkachev, Alexander, Tolmanis, Ivars, Tsarynna, Nataliia, Tsonev, Nikolay, Tulassay, Zsolt, Ueo, Tetsuya, Unal, Nalan, Valuyskikh, Ekaterina, Van Dop, Willemijn, Vasilevskaya, Olga, Venugopal, Kannan, Verstockt, Bram, Viamonte, Manuel, Vyshyvanyuk, Vira, Wang, Bangmao, Wang, Xiaoyan, Wang, Jiangbin, Wang, Yufang, Wei, Shu-chen, Weisshof, Roni, Wisam, Sbeit, Wojcik, Katarzyna, Yakovlev, Alexey, Yasuda, Hiroshi, Ye, Byongduk, Yen, Hsu-heng, Yilmaz, Hasan, Yokoyama, Yoko, Yoon, Hyuk, Yoshida, Takeshi, Yurkiv, Andriy, Zaha, Osamu, Zaltman, Cyrla, Zhan, Qiang, Zhang, Hongjie, Zhang, Shutian, Zhu, Lanxiang, Zou, Duowu, Zou, Xiaoping, and Zureikat, Firas

Abstract

Interleukin-23 inhibition is effective in treating ulcerative colitis. Guselkumab is a dual-acting, human IgG1, interleukin-23p19 subunit inhibitor that potently neutralises interleukin-23 and can bind to CD64. We aimed to evaluate the efficacy and safety of guselkumab as induction and maintenance therapy in patients with ulcerative colitis.

Published
2025
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11. Efficacy and safety of mirikizumab in patients with moderately-to-severely active Crohn's disease: a phase 3, multicentre, randomised, double-blind, placebo-controlled and active-controlled, treat-through study

Author

Ferrante, Marc, D'Haens, Geert, Jairath, Vipul, Danese, Silvio, Chen, Minhu, Ghosh, Subrata, Hisamatsu, Tadakazu, Kierkus, Jaroslaw, Siegmund, Britta, Bragg, Sonja Michelle, Crandall, Wallace, Durand, Frederick, Hon, Emily, Lin, Zhantao, Lopes, Michelle Ugolini, Morris, Nathan, Protic, Marijana, Carlier, Hilde, Sands, Bruce E, Tron, Emiliano, Dorado, Fernanda Dorado, Thin, Lena, Leong, Rupert, Seltenreich, Hans, Christensen, Britt, Croft, Anthony, Ghaly, Simon, Koch, Robert, Reinisch, Walter, Heeren, Sonja, Bossuyt, Peter, Ferrante, Marc, Maximiano, Fabio Luiz, Sassaki, Ligia Yukie, Baia, Carolina, Poli, Debora, de Sousa Carlos, Alexandre, de Magalhaes Francesconi, Carlos Fernando, De Sa Rolim, Alexander, Razera, Julio, Simoes Neto, Joaquim, Rocco, Rodrigo, Stifft, Jonathas, Soldera, Jonathan, Silva, Genoile, Mendes Clemente, Cintia, Di Felice Boratto, Sandra, Teixeira de Campos, Luciana, Rodrigues Borba, Marcelo, Rosenfeld, Gregory, Ponich, Terry, Lim, Allen, Williams, Chadwick, Musgrave, Bruce, Gauthier, Stephane, Liu, Wenjia, Wang, Chengdang, Guo, Hong, Chen, Chunxiao, Chen, Yan Chen, Cao, Qian, Zhong, Jie, Xu, Min, Wang, Yufang, Zheng, Changqing, Gao, Xiang, Chen, Youxiang, Miao, Yinglei, Wang, Lin, Liu, Deliang, Wang, Bangmao, Song, Zhengji, Liu, Xiaowei, Chen, Baili, Jiang, Yi, Zhan, Qiang, Zhang, Kaiguang, Shen, Hong, Li, Zhaotao, Wang, Xiaoyan, Wang, Mei Wang, Tian, De'an, Chen, Lei, Tang, Wen, Borzan, Vladimir, Krznaric, Zeljko, Volfova, Miroslava, Pumprla, Jiri, Veberova, Lucie, Tichy, Michal, Gregar, Jan, Stepek, David, Ulbrych, Jan, Drastich, Pavel, Papik, Zdenek, Matous, Jan, Lukas, Martin, Koskova, Radka, Fallingborg, Jan, Altwegg, Romain, Fotsing, Ginette, Laharie, David, Nancey, Stephane, Peyrin, Laurent, Schreiber, Stefan, Hoffmann, Jörg, Seidler, Ursula, Fechner, Lars, Arelin, Katrin, Contzen, Christel, Trenn, Guido, Schaum, Thomas, Schoettker, Katrin, Bachmann, Oliver, Encke, Jens, Ibe, Michael, Jakobeit, Christian, Varga, Marta, Salamon, Agnes, Kafony, Andras, Horvat, Gyula, Heringh, Zsanett, Bezzegh, Katalin, Izbeki, Ferenc, Szalai, Laszlo, Schnabel, Robert, Samanta, Jayanta, Banerjee, Rupa, Subramanian, Ganesh, Mukewar, Shrikant, Bansal, Naresh Kumar, Sood, Ajit, Shankar Bagepally, Ravi, Kumar, Porika Shravan, Shrimal, Pankaj, Shah, Saumin, Pai, Nitin, Ahuja, Vineet, Melzer, Ehud, Assy, Nimer, Goldin, Eran, Shirin, Haim, Segal, Arik, Lahat, Adi, Saibeni, Simone, Luzza, Francesco, Danese, Silvio, Caprioli, Flavio, Annunziata, Maria Laura, Fantini, Massimo, Matsuda, Koichiro, Takagi, Sho, Kanmura, Shuji, Goto, Mitsuhide, Ashida, Toshifumi, Nishimata, Nobuaki, Kawakami, Kazuhiko, Ishiguro, Yoh Ishiguro, Maemoto, Atsuo Maemoto, Naito, Yuji Naito, Naoe, Hideaki, Nakase, Hiroshi, Iida, Tomohiro, Akiyama, Junichi, Yoshioka, Masao, Abe, Yasuhiko, Takeuchi, Ken, Kawai, Mikio, Hirai, Fumihito, Horiki, Noriyuki, Park, Sang Hyoung, Park, Dong II, Kang, Sang Bum, Jung, Min Kyu, Jang, Byung Ik, Lee, Yoo Jin, Shin, SungJae, Kim, Tae-oh, Kim, Hyun-Soo, Lee, Bo-In, Lee, Jonghun, Kim, Hyo Jong, Choi, Chang Hwan, Kim, Dongwoo, Eun, Chang Soo, Kang, Ben, Pokrotnieks, Juris, Kiudelis, Gediminas, Ramirez, Karina, Vega Fonseca, Jose Luis, Laheij, Robert, Kierkus, Jaroslaw, Klopocka, Maria, Wylegala, Zbigniew, Mroziak, Beata, Wojcik, Katarzyna, Korczowski, Bartosz, Gawdis, Beata, Danilkiewicz, Wit, Olszanecka, Magdalena, Krzykowska, Jolanta, Jamrozik, Zofia, Duszynska, Malgorzata, Ciesiolkiewicz, Agnieszka, Baluta, Malgorzata, Horynski, Marek, Leszczyszyn, Jaroslaw, Rozumek, Grzegorz, Firkowski, Lukasz, Konopko, Marzena, Orleanski, Jakub, Filip, Rafal, Wiechowska, Anna, Niezgoda, Krzysztof, Mateescu, Radu, Craciun, Eugeniu, Chioncel, Camelia, Musat, Marioara, Voiosu, Theodor Alexandru, Trofimov, Vasily, Shchukina, Oksana, Pershko, Anatoly, Fedorishina, Olga, Chumakova, Galina, Bakulin, Igor, Osipenko, Marina, Nikolin, Denis, Barysheva, Olga, Alexeeva, Olga, Zakharov, Konstantin, Khodareva, Irina, Tkachev, Alexander, Golovenko, Alexey, Popova, Veronika, Kashnikov, Vladimir, Vershinina, Maria, Makarchuk, Pavel, Valuyskikh, Ekaterina, Crevar, Slobodanka, Svorcan, Petar, Radakovic, Tatjana, Hlavaty, Tibor, Bunganic, Ivan, Fedurco, Miroslav, Kalisova, Iveta, Balaz, Jozef, Mihalkanin, Lubomir, Martin Arranz, Maria Dolores, De Teresa Parreno, Luis, Sans Cuffi, Miquel, Hernandez Camba, Alejandro, Brand, Stephan, Juillerat, Pascal, Seibold, Frank, Demirci, Hakan, Tezel, Ahmet, Simsek, Halis, Kiyici, Murat, Gonen, Can, Hulagu, Sadettin, Karakan, Tarkan, Cekin, Ayhan, Altintas, Engin, Guven, Kadri, Akpinar, Hale, Ozin, Yasemin, Erzin, Yusuf, Demir, Mehmet, Temel, Tuncer, Lohdanidi, Tetiana, Ivanov, Valeriy, Ivanishyn, Olha, Golovchenko, Oleksandr, Gerasymenko, Oksana, Danyliuk, Svitlana, Vyshyvanyuk, Vira, Datsenko, Olena, Stanislavchuk, Mykola, Rishko, Yaroslava, Kyrychenko, Olga, Donets, Dmytro, Shapovalova, Yana, Yurkiv, Andriy, Oliinyk, Oleksandr, Tsarynna, Nataliia, Fediv, Oleksandr, Poplyonkin, Yevgen, Kaser, Arthur, Hoque, Syed, Thomas, Hawys, Iyengar, Shalini, Newman, Frederic, Fogel, Ronald, Pedersen, Peder, Gonzales, Chad, McCord, Gregory, Galambos, Michael, Lamb, Paul, Schneider, Jeffrey, Bhandari, Bal Raj, Weiss, Michael, Thai, Christine, Shapiro, Michael, Younes, Ziad, Murali, Narayanachar, Hou, Jason, Williams, Todd, Khalid, Omer, Hsu, Connie, Bartalos, Christopher, Arimie, Calin, Mumtaz, Syed, Crespo, Israel, Marchioni Beery, Renee, Tuskey, Anne, Gaible, Ryan, Cutler, Alan, Afzali, Anita, Stuart, Kevin, Ibegbu, Eric, Irizarry-Roman, Moises, Harris, Kimberly, Agyei, Kwadwo, Jones, Frances, Sheikh, Aasim, Zakko, Liam, Cohen, Erica, Duvall, George, Al Kharrat, Houssam, Wohlman, Robert, Holderman, William, Schulman, Alan, Lidofsky, Sheldon, Wayne, Peter, Victores, Luis, Stone, Christian, Onwueme, Kenolisa, Fischer, Monika, Shahid, Shabana, Moore, Keith, Katz, Jeffry, Bullock, Jeff, and Fahed, Julien

Abstract

Mirikizumab, a humanised monoclonal antibody that inhibits IL-23p19, is effective in moderate-to-severe ulcerative colitis. We aimed to evaluate the efficacy and safety of mirikizumab in patients with moderately-to-severely active Crohn's disease.

Published
2024
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14. Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study

Author

Peyrin-Biroulet, Laurent, primary, Allegretti, Jessica R., additional, Rubin, David T., additional, Bressler, Brian, additional, Germinaro, Matthew, additional, Huang, Kuan-Hsiang (Gary), additional, Shipitofsky, Nicole, additional, Zhang, Hongyan, additional, Wilson, Rebbecca, additional, Han, Chenglong, additional, Feagan, Brian G., additional, Sandborn, William J., additional, Panés, Julian, additional, Hisamatsu, Tadakazu, additional, Lichtenstein, Gary R., additional, Sands, Bruce E., additional, Dignass, Axel, additional, Abrahamovych, Orest, additional, Afanasieva, Halyna, additional, Aitova, Lilia, additional, Altintas, Engin, additional, Altwegg, Romain, additional, Andreev, Pavel, additional, Aomatsu, Kazuki, additional, Augustyn, Monika, additional, Balestrieri, Paola, additional, Begun, Jakob, additional, Brunatto, Luciana, additional, Bulgheroni, Diego, additional, Bunkova, Elena, additional, Cabello, Mercedes, additional, Cao, Qian, additional, Caprioli, Flavio, additional, Cerqueira, Rute, additional, Chen, Baili, additional, Chen, Chou-Chen, additional, Chen, Chou-Pin, additional, Chiu, Cheng-Tang, additional, Choi, Chang Hwan, additional, Cicala, Michele, additional, Datsenko, Olena, additional, Dewint, Pieter, additional, Domenech, Eugeni, additional, Dutré, Joris, additional, Duvall, George, additional, Fernandez, Juan, additional, Filip, Rafal, additional, Fogel, Ronald, additional, Fowler, Sharyle, additional, Fujii, Toshimitsu, additional, Fukata, Masayuki, additional, Furumoto, Yohei, additional, Gasbarrini, Antonio, additional, Gawdis-Wojnarska, Beata, additional, Gilletta, Cyrielle, additional, Gionchetti, Paolo, additional, Goldin, Eran, additional, Golovchenko, Oleksandr, additional, Gonciarz, Maciej, additional, Gonen, Can, additional, Segura, Gaston Gonzalez, additional, Gridnyev, Oleksii, additional, Gyokeres, Tibor, additional, Hébuterne, Xavier, additional, Hedin, Charlotte, additional, Hellström, Per, additional, Hilmi, Ida Normiha, additional, Horný, Ivo, additional, Horvat, Gyula, additional, Hoshi, Namiko, additional, Hrdlicka, Ludek, additional, Ishihara, Shunji, additional, Ivanishyn, Olha, additional, Jang, Byung Ik, additional, Junior, Odery, additional, Kagaya, Takashi, additional, Kanmura, Shuji, additional, Karakina, Marina, additional, Katsuhiko, Nakai, additional, Kierkus, Jaroslaw, additional, Kim, Hyo Jong, additional, Kim, Tae-Oh, additional, Kim, Young-Ho, additional, Kiss, Gyula G., additional, Klaus, Jochen, additional, Kleczkowski, Dariusz, additional, Klopocka, Maria, additional, Kobayashi, Taku, additional, Kobielusz-Gembala, Iwona, additional, Koo, Ja Seol, additional, Kopon, Adam, additional, Kravchenko, Tetiana, additional, Kudo, Masatoshi, additional, Kwon, Kwang An, additional, Lago, Paula, additional, Laharie, David, additional, Lawrance, Ian, additional, Leszczyszyn, Jaroslaw, additional, Li, Yan, additional, Lukas, Milan, additional, Maaser, Christian, additional, Maemoto, Atsuo, additional, Marusawa, Hiroyuki, additional, McBride, Matthew, additional, Mendu, Shoba, additional, Miheller, Pal, additional, Miyabayashi, Hideharu, additional, Mohl, Wolfgang, additional, Moore, Gregory, additional, Motoya, Satoshi, additional, Murali, Narayanachar, additional, Naem, Mohammed, additional, Nakajima, Koichi, additional, Nakamoto, Yasunari, additional, Nancey, Stéphane, additional, Neto, Joaquim, additional, Onizawa, Michio, additional, Ono, Yohei, additional, Osada, Taro, additional, Osipenko, Marina, additional, Owczarek, Danuta, additional, Patel, Bhaktasharan, additional, Patel, Kamal, additional, Petrova, Elina, additional, Poroshina, Elena, additional, Portela, Francisco, additional, Prystupa, Lyudmyla, additional, Rivero, Monserrat, additional, Roblin, Xavier, additional, Romatowski, Jacek, additional, Rydzewska, Grazyna, additional, Saibeni, Simone, additional, Sakuraba, Hirotake, additional, Samaan, Mark, additional, Schultz, Michael, additional, Schulze, Joerg, additional, Sedghi, Shahriar, additional, Seidler, Ursula, additional, Shin, Sung Jae, additional, Stanislavchuk, Mykola, additional, Stokesberry, David, additional, Suzuki, Takayoshi, additional, Taguchi, Hiroki, additional, Tankova, Lyudmila, additional, Thin, Lena, additional, Tkachev, Alexander, additional, Torrealba, Leyanira, additional, Tsarynna, Nataliia, additional, Tulassay, Zsolt, additional, Ueo, Tetsuya, additional, Valuyskikh, Ekaterina, additional, Vasilevskaya, Olga, additional, Viamonte, Manuel, additional, Wei, Shu-Chen, additional, Weisshof, Roni, additional, Wojcik, Katarzyna, additional, Ye, Byong Duk, additional, Yen, Hsu-Heng, additional, Yoon, Hyuk, additional, Yoshida, Kosuke, additional, Yurkiv, Andriy, additional, Zaha, Osamu, additional, and Zhan, Qiang, additional

Published
2023
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17. Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies

Author

Goel, Gautam, King, Tim, Daveson, A James, Andrews, Jane M, Krishnarajah, Janakan, Krause, Richard, Brown, Gregor J E, Fogel, Ronald, Barish, Charles F, Epstein, Roger, Kinney, Timothy P, Miner, Philip B, Jr, Tye-Din, Jason A, Girardin, Adam, Taavela, Juha, Popp, Alina, Sidney, John, Mäki, Markku, Goldstein, Kaela E, Griffin, Patrick H, Wang, Suyue, Dzuris, John L, Williams, Leslie J, Sette, Alessandro, Xavier, Ramnik J, Sollid, Ludvig M, Jabri, Bana, and Anderson, Robert P

Published
2017
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19. Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study

Author

Tye-Din, Jason A, primary, Daveson, A James M, additional, Goel, Gautam, additional, Goldstein, Kaela E, additional, Hand, Holly L, additional, Neff, Kristin M, additional, Popp, Alina, additional, Taavela, Juha, additional, Maki, Markku, additional, Isola, Jorma, additional, Williams, Leslie J, additional, Truitt, Kenneth E, additional, Anderson, Robert P, additional, Adams, Atoya, additional, Andrews, Jane M, additional, Behrend, Clint E, additional, Brown, Gregor J E, additional, Chen Yi Mei, Swee Lin, additional, Coates, Allan G, additional, DiMarino, Anthony J, additional, Ee, Hooi, additional, Elliott, David E, additional, Epstein, Roger M, additional, Feyen, Bryan John, additional, Fogel, Ronald P, additional, Friedenberg, Keith Alan, additional, Gearry, Richard B, additional, Gerdis, Michael S, additional, Goldstein, Michael J, additional, Gupta, Vipin K, additional, Holmes, Robert John, additional, Holtmann, Gerald J, additional, Idarraga, Samuel H, additional, James, George W, additional, King, Tim, additional, Klein, Terry D, additional, Kupfer, Sonia S, additional, Lebwohl, Benjamin, additional, Lowe, Matthew John, additional, Murray, Joseph A, additional, Newton, Eric B, additional, Quinn, Dean, additional, Radin, David M, additional, Ritter, Timothy E, additional, Stacey, Helen Lee, additional, Strout, Cynthia B, additional, Stubbs, Richard S, additional, Thackwray, Susan Lynn, additional, Trivedi, Vivek M, additional, Weber, John R, additional, and Wilson, Scott A, additional

Published
2023
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20. Plecanatide Improves Symptoms of Irritable Bowel Syndrome with Constipation: Results of an Integrated Efficacy and Safety Analysis of Two Phase 3 Trials

Author

Brenner,Darren M, Dorn,Spencer D, Fogel,Ronald P, Christie,Jennifer, Laitman,Adam P, Rosenberg,Jonathan, Brenner,Darren M, Dorn,Spencer D, Fogel,Ronald P, Christie,Jennifer, Laitman,Adam P, and Rosenberg,Jonathan

Abstract

Darren M Brenner,1 Spencer D Dorn,2 Ronald P Fogel,3 Jennifer Christie,4 Adam P Laitman,5 Jonathan Rosenberg6 1Internal Medicine-Gastroenterology, Northwestern University-Feinberg School of Medicine, Chicago, IL, USA; 2Division of Gastroenterology and Hepatology, UNC School of Medicine, Chapel Hill, NC, USA; 3Digestive Health Center of Michigan, Chesterfield, MI, USA; 4Emory University School of Medicine, Atlanta, GA, USA; 5Salix Pharmaceuticals, Bridgewater, NJ, USA; 6GI Alliance of Illinois, Gurnee, IL, USACorrespondence: Darren M Brenner, MD, FACG, AGAF, RFF, Northwestern Memorial Hospital/Arkes Family Pavilion, 676 N St Clair Street, Suite 1400, Chicago, IL, 60611, USA, Tel +1 312 695 8132, Fax +1 312 695 3999, Email Darren.Brenner@nm.orgPurpose: Patients with irritable bowel syndrome with constipation (IBS-C) experience abdominal pain with altered bowel movements. Plecanatide is indicated as IBS-C treatment in adults. This integrated analysis further characterizes plecanatide efficacy and safety in IBS-C.Patients and Methods: Data pooled from 2 identically designed phase 3 trials included adults with IBS-C randomized to plecanatide 3 mg or 6 mg, or placebo once daily for 12 weeks. A daily diary recorded stool frequency/symptoms, with abdominal pain, bloating, cramping, discomfort, fullness, and straining intensity individually rated. Overall response (primary endpoint) was defined as ≥ 30% improvement from baseline in average worst abdominal pain severity and increase of ≥ 1 complete spontaneous bowel movement, during same week (composite), for ≥ 6 of 12 weeks. Secondary endpoints included sustained response (overall response, plus meeting weekly composite criteria during ≥ 2 of last 4 treatment weeks) and changes from baseline in individual symptoms. Safety assessments included adverse event monitoring.Results: Overall, 2176 patients (74.0% female; mean [SD] age, 43.5 [14.1] years) were included in efficacy analyses (plecanatide 3 mg [n = 724], 6 mg [n

Published
2023

23. Long-Term Treatment of Eosinophilic Esophagitis With Budesonide Oral Suspension

Author

Dellon, Evan S., primary, Collins, Margaret H., additional, Katzka, David A., additional, Mukkada, Vincent A., additional, Falk, Gary W., additional, Morey, Robin, additional, Goodwin, Bridgett, additional, Eisner, Jessica D., additional, Lan, Lan, additional, Desai, Nirav K., additional, Williams, James, additional, Hirano, Ikuo, additional, Baum, Curtis, additional, Bekal, Pradeep, additional, Chaletsky, David, additional, Chehade, Mirna, additional, Clark, Larry, additional, Dellon, Evan, additional, Dimmitt, Reed, additional, Dulitz, David, additional, Falk, Gary, additional, Fogel, Ronald, additional, Friedenberg, Keith, additional, Gabbard, Scott, additional, Gentry, Andrew, additional, Gold, Benjamin, additional, Goldstein, Michael, additional, Gupta, Sandeep, additional, Hsu-Blatman, Karen, additional, Jayanty, Vikram, additional, Katzka, David, additional, Kunnathur, Vidhya, additional, Lee, John, additional, Leung, John, additional, Markowitz, Jonathan, additional, Menard-Katcher, Calies, additional, Mitlyng, Benjamin, additional, Moussa, Sam E., additional, Mukkada, Vincent, additional, O’Gorman, Molly, additional, Olazagasti, Juan, additional, Ritter, Timothy, additional, Sayej, Wael, additional, Schroeder, Shauna, additional, Smadi, Yamen, additional, Soteres, Daniel, additional, Stathos, Theodore, additional, Vaezi, Michael F., additional, Whitlock, Tom, additional, Wo, John, additional, Younes, Ziad, additional, and Zakko, Salam, additional

Published
2022
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24. Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn's disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial

Author

Sands, Bruce E, primary, Irving, Peter M, additional, Hoops, Timothy, additional, Izanec, James L, additional, Gao, Long-Long, additional, Gasink, Christopher, additional, Greenspan, Andrew, additional, Allez, Matthieu, additional, Danese, Silvio, additional, Hanauer, Stephen B, additional, Jairath, Vipul, additional, Kuehbacher, Tanja, additional, Lewis, James D, additional, Loftus, Edward V, additional, Mihaly, Emese, additional, Panaccione, Remo, additional, Scherl, Ellen, additional, Shchukina, Oksana B, additional, Sandborn, William J, additional, Afzali, Anita, additional, Aitova, Lilia, additional, Aldeguer i Mante, Xavier, additional, Altorjay, István, additional, Argüelles Arias, Federico, additional, Armuzzi, Alessandro, additional, Augustyn, Monika, additional, Bafutto, Mauro, additional, Barrio, Jesus, additional, Begun, Jakob, additional, Behrend, Clint, additional, Bezemer, Geert, additional, Bonnaud, Guillaume, additional, Brankovic, Marija, additional, Byung, Ik Jang, additional, Calvet Calvo, Xavier, additional, Chachu, Karen, additional, Chebli, Julio Maria Fonseca, additional, Cheon, Jae Hee, additional, Cichoz-Lach, Halina, additional, Clark, Larry, additional, Cummings, Fraser, additional, Dalal, Kunal, additional, De Boer, Nanne, additional, De Lourdes Ferrari, Maria, additional, Désilets, Etienne, additional, Dugalic, Predrag, additional, Duvall, George, additional, Fedorishina, Olga, additional, Filip, Rafal, additional, Flores, Cristina, additional, Fogel, Ronald, additional, Fon, James, additional, Frankel, Michael, additional, Friedenberg, Keith, additional, Fries, Walter, additional, Galina, Vassileva, additional, Gietka, Piotr, additional, Goel, Rishi, additional, Hasselblatt, Peter, additional, Herfarth, Hans, additional, Herszényi, László, additional, Hindryckx, Pieter, additional, Hoentjen, Frank, additional, Horjus Talabur Horje, Carmen, additional, Iduru, Satish, additional, Irving, Peter, additional, Isfort, Robert, additional, Jones, Michael, additional, Kalimullina, Dilara, additional, Katz, Jeffry, additional, Kaur, Manreet, additional, Khurana, Sunil K, additional, Kim, Joo Sung, additional, Kim, Youngho, additional, Kleczkowski, Dariusz, additional, Knezevic, Slavko, additional, Knoll, Aaron, additional, Korman, Louis Y, additional, Kotzev, Iskren, additional, Kulyapin, Andrey, additional, Lee, Kang Moon, additional, Leemreis, Desiree, additional, Leszczyszyn, Jaroslaw, additional, Limdi, Jimmy, additional, Lissauer, Jack, additional, Loftus, Edward, additional, Malecka-Panas, Ewa, additional, Marshall, John, additional, Mihály, Emese, additional, Milan, Lukas, additional, Monteleone, Giovanni, additional, Nagorni, Aleksandar, additional, Owczarek, Danuta, additional, Palekar, Nichole, additional, Park, Young Soo, additional, Park, Sang Hyoung, additional, Parra, Rogério, additional, Patai, Árpád, additional, Patel, Kamal, additional, Patel, Bhaktasharan, additional, Pershko, Anatoly, additional, Petrova, Elina, additional, Pineton de Chambrun, Guillaume, additional, Randall, Charles, additional, Riestra Menendez, Sabino, additional, Ritter, Timothy, additional, Rivero, Montserrat, additional, Roblin, Xavier, additional, Rocca, Rodolfo, additional, Romatowski, Jacek, additional, Rydzewska, Grazyna, additional, Saibeni, Simone, additional, Salzberg, Bruce, additional, Sarles, Harry, additional, Saunders, John, additional, Savarino, Edoardo Vincenzo, additional, Serclova, Zuzana, additional, Shchukina, Oksana, additional, Siegel, Jonathan, additional, Soofi, Najm, additional, Sparrow, Miles, additional, Stokesberry, David, additional, Suiter, Daniel, additional, Svorcan, Petar, additional, Tkachev, Alexander, additional, Tsonev, Nikolay, additional, Tünde, Kristóf, additional, Ulbrych, Jan, additional, Vanasek, Tomas, additional, Varga, Márta, additional, Vermeire, Severine, additional, Vicente Lidon, Raquel, additional, Weiss, Michael L, additional, Wesley, Emma, additional, Winstead, Nathaniel, additional, Wojcik, Katarzyna, additional, Wypych, Joanna, additional, Zaltman, Cyrla, additional, and Zdena, Zadorova, additional

Published
2022
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25. 535: EFFICACY AND SAFETY OF VIBRANT® CAPSULE FOR CHRONIC IDIOPATHIC CONSTIPATION (CIC): RANDOMIZED, DOUBLE-BLIND, MULTICENTER, PLACEBO-CONTROLLED, PHASE III TRIAL

Author

Rao, Satish S., primary, Quigley, Eamonn, additional, Chey, William D., additional, Sharma, Amol, additional, Dinh, Dinh V., additional, Dunn, Leonard, additional, Fogel, Ronald P., additional, Romero, Sandor, additional, Teltser, Matthew, additional, Morin, Robert, additional, Torres, Louis, additional, Surowitz, Ronald, additional, Reddy, Vishnu, additional, Wayne, Jeffrey D., additional, Snook, Murray, additional, Goldstein, Gary, additional, Rubino, John, additional, Freeman, George, additional, Lumicao, Benjamin, additional, Greenwald, James, additional, Zopo, Alex, additional, Wild, James, additional, Hellstern, Paul, additional, Murray, Alexander, additional, Usdan, Lisa, additional, Whitmer, Daniel, additional, Oza, Amita, additional, Friedenberg, Keith, additional, and Lembo, Anthony, additional

Published
2022
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27. Etrolizumab for maintenance therapy in patients with moderately to severely active ulcerative colitis (LAUREL): a randomised, placebo-controlled, double-blind, phase 3 study

Author

Vermeire, Severine, primary, Lakatos, Peter L, additional, Ritter, Timothy, additional, Hanauer, Stephen, additional, Bressler, Brian, additional, Khanna, Reena, additional, Isaacs, Kim, additional, Shah, Saumin, additional, Kadva, Alysha, additional, Tyrrell, Helen, additional, Oh, Young S, additional, Tole, Swati, additional, Chai, Akiko, additional, Pulley, Jennifer, additional, Eden, Christopher, additional, Zhang, Wenhui, additional, Feagan, Brian G, additional, Abraham, Philip, additional, Acir Crippa Júnior, Mauro, additional, Aguilar, Humberto, additional, Ahmed, Tasneem, additional, Altorjay, Istvan, additional, Andersen, Vibeke, additional, Arai, Ronen, additional, Arnold, Hays, additional, Ausk, Karlee, additional, Axler, Jeffrey, additional, Ayub, Kamran, additional, Balekuduru, Avinash, additional, Barbalaco Neto, Guerino, additional, Bassan, Isaac, additional, Behm, Brian, additional, Bekal, Pradeep, additional, Bhatia, Shobna, additional, Bod, Barnabas, additional, Brandão Mello, Carlos Eduardo, additional, Brandeburova, Julia, additional, Breedt, Johannes, additional, Chopey, Ivan, additional, Connor, Michael, additional, Corlin, Richard, additional, Cortez Hernandez, Carlos Alejandro, additional, De, Arijit, additional, de Sá Rolim, Alexander, additional, Di Felice Boratto, Sandra, additional, Dixon, Tyler, additional, Dourado Poli, Debora, additional, Dresner, David, additional, Du Vall, George Aaron, additional, Ebert, Matthias, additional, Ehehalt, Robert, additional, Ertan, Atilla, additional, Escarcega Valencia, Ruben, additional, Etzel, Jason, additional, Fallingborg, Jan, additional, Feagan, Brian, additional, Fedurco, Miroslav, additional, Fernandez Castro, Enrique, additional, Ferreira de Almeida Borges, Valéria, additional, Finklestein, Mark, additional, Fischer, Andreas, additional, Fleisher, Mark, additional, Flores Rendon, Angel Ricardo, additional, Fogel, Ronald, additional, Franceschi Junior, Osvaldo, additional, Freedland, Curtis, additional, Gatof, David, additional, Gill, Kanwar, additional, Glerup, Henning, additional, Gokak, Vardaraj, additional, Goldin, Eran, additional, Gomez Jaramillo, Hector Alejandro, additional, Gupta, Nitin, additional, Gurzo, Zoltan, additional, Gyrina, Olga, additional, Habeeb, Mohammed Aejaz, additional, Hardi, Robert, additional, Harlan, William, additional, Hemaidan, Ammar, additional, Heyman, Melvin, additional, Hoffmann, Peter, additional, Holderman, William, additional, Holtkamp-Endemann, Frank, additional, Horvat, Gyula, additional, Israeli, Eran, additional, Jankiel Miszputen, Sender, additional, Jensen, Søren, additional, Johnson, Kenneth, additional, Jones, Jennifer, additional, Junior, Osvaldo, additional, Kadleckova, Barbora, additional, Kalla, Mukesh, additional, Kallo, Zsuzsanna, additional, Karyotakis, Nicholas, additional, Katz, Lior, additional, Katz, Leo, additional, Kaur, Nirmal, additional, Kohout, Pavel, additional, Lakatos, Peter, additional, Larriva de los Reyes, Emmanuel, additional, Lee, Robert, additional, Leman, Bernard, additional, Levchenko, Olena, additional, Levine, Henry, additional, Libanez Bessa Campelo Braga, Lúcia, additional, Loftus, Edward, additional, Lohdanidi, Tetiana, additional, Longman, Randy, additional, Lozano, Josefina, additional, Maaser, Christian, additional, Madi-Szabo, Laszlo, additional, Malluta, Everson Fernando, additional, Marshall, John, additional, Martinez Silva, Francisca, additional, Maynard, Kenneth, additional, Meder, Agnieszka, additional, Mehta, Chetan, additional, Minarik, Peter, additional, Mueller, Joachim, additional, Mukewar, Shrikant, additional, Nagy, Bela, additional, Neiko, Vasyl, additional, Neurath, Markus, additional, Nichol, Brian, additional, Novick, James, additional, Pai, Nitin, additional, Pandak, William, additional, Panigrahi, Sarat, additional, Pape, Ulrich-Frank, additional, Paraná, Raymundo, additional, Parekh, Nimisha, additional, Patel, Bhaktasharan, additional, Pecsi, Gyula, additional, Peralta, Sergio, additional, Pesta, Martin, additional, Peterfai, Eva, additional, Petruzzellis, Carlo, additional, Petryka, Robert, additional, Pica, Roberta, additional, Piniella, Carlos, additional, Pratha, Vijayalakshmi, additional, Prochazka, Vlastimil, additional, Prokopchuk, Sergey, additional, Prystupa, Ludmyla, additional, Puri, Amarender, additional, Rainis, Tova, additional, Ramesh Kumar, Bhashyakarla, additional, Ramos Júnior, Odery, additional, Rishko, Iaroslava, additional, Robbins, Bryan, additional, Rock, Elizabeth, additional, Rodrigues Borba, Marcelo, additional, Rodriguez, Miguel, additional, Rozciecha, Jerzy, additional, Ruiz Flores, Azalia Yuriria, additional, Rydzewska, Grazyna, additional, Safadi, Rifaat, additional, Saibeni, Simone, additional, Schirbel, Anja, additional, Schmiegel, Wolff, additional, Schnabel, Róbert, additional, Schneider, Herbert, additional, Segui, Armando, additional, Seidelin, Jakob, additional, Seidler, Ursula, additional, Sellin, Joseph, additional, Shafran, Ira, additional, Sheikh, Aasim, additional, Sherman, Alex, additional, Shirin, Haim, additional, Shukla, Akash, additional, Siddiqui, Firdous, additional, Sike, Robert, additional, Sood, Ajit, additional, Stallmach, Andreas, additional, Stanislavchuk, Mykola, additional, Staun, Michael, additional, Stein, Daniel, additional, Steinberg, Alon, additional, Steinhart, Hillary, additional, Stifft, Jonathas, additional, Tandon, Rakesh, additional, Tantry, Vishwanath, additional, Thiwan, Syed, additional, Treiber, Matthias, additional, Ulbrych, Jan, additional, Valentine, John, additional, Vasudeva, Rajeev, additional, Vaughn, Byron, additional, Velasco, Brenda, additional, Vincze, Aron, additional, Volfova, Miroslava, additional, Waterman, Mattitiahu, additional, Weiss, L. Michael, additional, Wiesner, Elise, additional, Williams, Alonzo, additional, Witthoeft, Thomas, additional, Wohlman, Robert, additional, Wright, John, additional, Yamamoto Furusho, Jesus Kazuo, additional, Younes, Ziad, additional, Yousuf, Khurshid, additional, Zborivskyy, Yaroslav, additional, Zeuzem, Stefan, additional, and Zhdan, Vyacheslav, additional

Published
2022
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29. Fr531 EFFICACY AND SAFETY OF FILGOTINIB AS MAINTENANCE THERAPY FOR PATIENTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS: RESULTS FROM THE PHASE 2B/3 SELECTION STUDY

Author

Peyrin-Biroulet, Laurent, primary, Loftus, Edward V., additional, Danese, Silvio, additional, Vermeire, Séverine, additional, Sandborn, William J., additional, Fogel, Ronald P., additional, Nijhawan, Sandeep, additional, Kempinski, Radoslaw, additional, Filip, Rafal, additional, Hospodarskyy, Ihor, additional, McNally, John, additional, Yun, Chohee, additional, Zhao, Sally, additional, Liu, Xiaopeng, additional, Tasset, Chantal T., additional, Besuyen, Robin, additional, Watanabe, Mamoru, additional, Schreiber, Stefan, additional, Rogler, Gerhard, additional, Hibi, Toshifumi, additional, and Feagan, Brian G., additional

Published
2021
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34. Neurons in the vagal complex of the rat respond to mechanical and chemical stimulation of the GI tract

Author

Zhang, Xueguo, Renehan, William E., and Fogel, Ronald

Subjects
Vagus nerve -- Physiological aspects, Neural circuitry -- Research, Neurons -- Physiological aspects, Biological sciences
Abstract

Intracellular and extracellular recording and intracellular labelling of neurons in the solitary tract nucleus and the vagus nerve motor nucleus were undertaken to investigate the vagovagal reflex response to acid in the proximal small intestine. Results reveal that the neurons in these nuclei were responsive to chemical stimuli and a majority was even sensitive to duodenal distention. These results verify the presence of the vagovagal reflex that may ultimately be protective of the intestinal mucosa.

Published
1998

36. Intestinal distension alters vagal efferent activity and small intestinal transport in vivo

Author

Chu, Xianxiang, Zhang, Xueguo, Renehan, William E., Beierwaltes, William H., and Fogel, Ronald

Subjects
Intestines -- Physiological aspects, Vagus nerve -- Physiological aspects, Biological sciences
Abstract

The influence of distention of anintestinal segment on water absorption at another segment noncontinuous with the distended region was investigated in rats. Results show that absorption in the noncontiguous segment is promoted by intestinal distention in subjects withsevered splanchnic nerves and intact vagi. Further, neural activity was reducedin 24 out of 26 vagal efferents after intestinal distention. This effect was abolished in subjects with transected afferent vagi. This suggests that distention activates a vagal circuit in subjects with trasected splanchnic nerves.

Published
1993

44. Design of the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial

Author

Prorok, Philip C., Andriole, Gerald L., Bresalier, Robert S., Buys, Saundra S., Chia, David, David Crawford, E., Fogel, Ronald, Gelmann, Edward P., Gilbert, Fred, Hasson, Marsha A., Hayes, Richard B., Johnson, Christine Cole, Mandel, Jack S., Oberman, Albert, O'Brien, Barbara, Oken, Martin M., Rafla, Sameer, Reding, Douglas, Rutt, Wilmer, Weissfeld, Joel L., Yokochi, Lance, and Gohagan, John K.

Published
2000
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48. Responsiveness of Endoscopic Indices of Disease Activity for Crohn’s Disease

Author

Khanna, Reena, primary, Zou, GuangYong, additional, Stitt, Larry, additional, Feagan, Brian G, additional, Sandborn, William J, additional, Rutgeerts, Paul, additional, McDonald, John W D, additional, Dubcenco, Elena, additional, Fogel, Ronald, additional, Panaccione, Remo, additional, Jairath, Vipul, additional, Nelson, Sigrid, additional, Shackelton, Lisa M, additional, Huang, Bidan, additional, Zhou, Qian, additional, Robinson, Anne M, additional, Levesque, Barrett G, additional, and D'Haens, Geert, additional

Published
2017
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49. Corrigendum: Responsiveness of Endoscopic Indices of Disease Activity for Crohn’s Disease

Author

Khanna, Reena, primary, Zou, GuangYong, additional, Stitt, Larry, additional, Feagan, Brian G, additional, Sandborn, William J, additional, Rutgeerts, Paul, additional, McDonald, John W D, additional, Dubcenco, Elena, additional, Fogel, Ronald, additional, Panaccione, Remo, additional, Jairath, Vipul, additional, Nelson, Sigrid, additional, Shackelton, Lisa M, additional, Huang, Bidan, additional, Zhou, Qian, additional, Robinson, Anne M, additional, Levesque, Barrett G, additional, and D'Haens, Geert, additional

Published
2017
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