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2,908 results on '"Fauci, Anthony"'

2. 1 Introduction

Author

Fauci, Anthony S., Ghebreyesus, Tedros Adhanom, Sorenson, Robert A., editor, Higgs, Elizabeth S., Editor-in-Chief, Fallah, Mosoka P., Section Editor, Lurie, Nicole, Section Editor, McNay, Laura A., Section Editor, and Smith, Peter G., Section Editor

Published
2024
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3. Anthony Fauci Talks New Book With Stephen Colbert

Author

Fauci, Anthony S.

Subjects
Social service, Books, Ex-presidents
Abstract

Anthony Fauci stopped by the Late Show With Stephen Colbert to discuss his new memoir. Fauci, who became a national celebrity during the Covid-19 pandemic in his role as the [...]

Published
2024

5. My West Nile Virus Nightmare

Author

Fauci, Anthony

Subjects
West Nile fever -- Care and treatment -- Distribution -- Research, Public health administration, Company distribution practices, General interest, News, opinion and commentary
Abstract

After I spent more than 50 years chasing and fighting viruses, one fought back and nearly took me down. I speak of the West Nile virus, delivered by the deadliest [...]

Published
2024

7. Scientific advances and the end of tuberculosis: a report from the Lancet Commission on Tuberculosis

Author

Reid, Michael, Agbassi, Yvan Jean Patrick, Arinaminpathy, Nimalan, Bercasio, Alyssa, Bhargava, Anurag, Bhargava, Madhavi, Bloom, Amy, Cattamanchi, Adithya, Chaisson, Richard, Chin, Daniel, Churchyard, Gavin, Cox, Helen, Denkinger, Claudia M, Ditiu, Lucica, Dowdy, David, Dybul, Mark, Fauci, Anthony, Fedaku, Endalkachew, Gidado, Mustapha, Harrington, Mark, Hauser, Janika, Heitkamp, Petra, Herbert, Nick, Herna Sari, Ani, Hopewell, Philip, Kendall, Emily, Khan, Aamir, Kim, Andrew, Koek, Irene, Kondratyuk, Sergiy, Krishnan, Nalini, Ku, Chu-Chang, Lessem, Erica, McConnell, Erin V, Nahid, Payam, Oliver, Matt, Pai, Madhukar, Raviglione, Mario, Ryckman, Theresa, Schäferhoff, Marco, Silva, Sachin, Small, Peter, Stallworthy, Guy, Temesgen, Zelalem, van Weezenbeek, Kitty, Vassall, Anna, Velásquez, Gustavo E, Venkatesan, Nandita, Yamey, Gavin, Zimmerman, Armand, Jamison, Dean, Swaminathan, Soumya, and Goosby, Eric

Published
2023
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8. Prolonged viral suppression with anti-HIV-1 antibody therapy

Author

Gaebler, Christian, Nogueira, Lilian, Stoffel, Elina, Oliveira, Thiago Y., Breton, Gaëlle, Millard, Katrina G., Turroja, Martina, Butler, Allison, Ramos, Victor, Seaman, Michael S., Reeves, Jacqueline D., Petroupoulos, Christos J., Shimeliovich, Irina, Gazumyan, Anna, Jiang, Caroline S., Jilg, Nikolaus, Scheid, Johannes F., Gandhi, Rajesh, Walker, Bruce D., Sneller, Michael C., Fauci, Anthony, Chun, Tae-Wook, Caskey, Marina, and Nussenzweig, Michel C.

Published
2022
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9. Combination anti-HIV antibodies provide sustained virological suppression

Author

Sneller, Michael C., Blazkova, Jana, Justement, J. Shawn, Shi, Victoria, Kennedy, Brooke D., Gittens, Kathleen, Tolstenko, Jekaterina, McCormack, Genevieve, Whitehead, Emily J., Schneck, Rachel F., Proschan, Michael A., Benko, Erika, Kovacs, Colin, Oguz, Cihan, Seaman, Michael S., Caskey, Marina, Nussenzweig, Michel C., Fauci, Anthony S., Moir, Susan, and Chun, Tae-Wook

Published
2022
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10. The V2 loop of HIV gp120 delivers costimulatory signals to CD4⁺ T cells through Integrin α₄β₇ and promotes cellular activation and infection

Author

Goes, Livia R., Sajani, Alia, Sivro, Aida, Olowojesiku, Ronke, Ray, Jocelyn C., Perrone, Ian, Yolitz, Jason, Girard, Alexandre, Leyre, Louise, Wibmer, Constantinos Kurt, Morris, Lynn, Gorini, Giacomo, Franchini, Genoveffa, Mason, Rosemarie D., Roederer, Mario, Mehandru, Saurabh, Soares, Marcelo A., Cicala, Claudia, Fauci, Anthony S., and Arthos, James

Published
2020

11. A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques

Author

Zhang, Peng, Narayanan, Elisabeth, Liu, Qingbo, Tsybovsky, Yaroslav, Boswell, Kristin, Ding, Shilei, Hu, Zonghui, Follmann, Dean, Lin, Yin, Miao, Huiyi, Schmeisser, Hana, Rogers, Denise, Falcone, Samantha, Elbashir, Sayda M., Presnyak, Vladimir, Bahl, Kapil, Prabhakaran, Madhu, Chen, Xuejun, Sarfo, Edward K., Ambrozak, David R., Gautam, Rajeev, Martin, Malcom A., Swerczek, Joanna, Herbert, Richard, Weiss, Deborah, Misamore, Johnathan, Ciaramella, Giuseppe, Himansu, Sunny, Stewart-Jones, Guillaume, McDermott, Adrian, Koup, Richard A., Mascola, John R., Finzi, Andrés, Carfi, Andrea, Fauci, Anthony S., and Lusso, Paolo

Published
2021
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12. Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7.

Author

Lertjuthaporn, Sakaorat, Cicala, Claudia, Van Ryk, Donald, Liu, Matthew, Yolitz, Jason, Wei, Danlan, Nawaz, Fatima, Doyle, Allison, Horowitch, Brooke, Park, Chung, Lu, Shan, Lou, Yang, Wang, Shixia, Pan, Ruimin, Jiang, Xunqing, Villinger, Francois, Byrareddy, Siddappa, Santangelo, Philip, Morris, Lynn, Wibmer, Constantinos, Biris, Kristin, Mason, Rosemarie, Gorman, Jason, Hiatt, Joseph, Martinelli, Elena, Roederer, Mario, Fujikawa, Dai, Gorini, Giacomo, Franchini, Genoveffa, Arakelyan, Anush, Ansari, Aftab, Pattanapanyasat, Kovit, Kong, Xiang-Peng, Fauci, Anthony, and Arthos, James

Subjects
AIDS Vaccines, Animals, Antibodies, Monoclonal, Binding Sites, Cell Line, Tumor, Epitopes, HIV Antibodies, HIV Envelope Protein gp120, HIV Infections, HIV-1, Integrins, Macaca, Protein Binding, Protein Interaction Domains and Motifs, SAIDS Vaccines, Simian Acquired Immunodeficiency Syndrome, Simian Immunodeficiency Virus, Vaccination
Abstract

The GI tract is preferentially targeted during acute/early HIV-1 infection. Consequent damage to the gut plays a central role in HIV pathogenesis. The basis for preferential targeting of gut tissues is not well defined. Recombinant proteins and synthetic peptides derived from HIV and SIV gp120 bind directly to integrin α4β7, a gut-homing receptor. Using both cell-surface expressed α4β7 and a soluble α4β7 heterodimer we demonstrate that its specific affinity for gp120 is similar to its affinity for MAdCAM (its natural ligand). The gp120 V2 domain preferentially engages extended forms of α4β7 in a cation -sensitive manner and is inhibited by soluble MAdCAM. Thus, V2 mimics MAdCAM in the way that it binds to α4β7, providing HIV a potential mechanism to discriminate between functionally distinct subsets of lymphocytes, including those with gut-homing potential. Furthermore, α4β7 antagonists developed for the treatment of inflammatory bowel diseases, block V2 binding to α4β7. A 15-amino acid V2 -derived peptide is sufficient to mediate binding to α4β7. It includes the canonical LDV/I α4β7 binding site, a cryptic epitope that lies 7-9 amino acids amino terminal to the LDV/I, and residues K169 and I181. These two residues were identified in a sieve analysis of the RV144 vaccine trial as sites of vaccine -mediated immune pressure. HIV and SIV V2 mAbs elicited by both vaccination and infection that recognize this peptide block V2-α4β7 interactions. These mAbs recognize conformations absent from the β- barrel presented in a stabilized HIV SOSIP gp120/41 trimer. The mimicry of MAdCAM-α4β7 interactions by V2 may influence early events in HIV infection, particularly the rapid seeding of gut tissues, and supports the view that HIV replication in gut tissue is a central feature of HIV pathogenesis.

Published
2018

13. Defective HIV-1 proviruses produce viral proteins

Author

Imamichi, Hiromi, Smith, Mindy, Adelsberger, Joseph W., Izumi, Taisuke, Scrimieri, Francesca, Sherman, Brad T., Rehm, Catherine A., Imamichi, Tomozumi, Pau, Alice, Catalfamo, Marta, Fauci, Anthony S., and Lane, H. Clifford

Published
2020

14. Distinct mechanisms of long-term virologic control in two HIV-infected individuals after treatment interruption of anti-retroviral therapy

Author

Blazkova, Jana, Gao, Feng, Marichannegowda, Manukumar Honnayakanahalli, Justement, J. Shawn, Shi, Victoria, Whitehead, Emily J., Schneck, Rachel F., Huiting, Erin D., Gittens, Kathleen, Cottrell, Mackenzie, Benko, Erika, Kovacs, Colin, Lack, Justin, Sneller, Michael C., Moir, Susan, Fauci, Anthony S., and Chun, Tae-Wook

Published
2021
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15. Forty years of investment in HIV research: progress towards ending the HIV pandemic and preparation for future pandemics

Author

Read, Sarah W., Kim, Peter, Marovich, Mary, Dieffenbach, Carl W., and Fauci, Anthony S.

Subjects
HIV (Viruses) -- Prevention -- Care and treatment, Medical research -- Investments, Medicine, Experimental -- Investments, Epidemics -- Control -- United Kingdom, Company investment, Health
Abstract

Since the beginning of the HIV pandemic, sustained and substantial investment in biomedical research and community engagement has led to extraordinary progress towards ending the HIV pandemic and laid a [...]

Published
2022
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17. Expanded Access of Unproven Drugs: Not the Final Word.

Author

Lane, H. Clifford and Fauci, Anthony S.

Subjects
PREVENTION of epidemics, HEALTH services accessibility, MONKEYPOX, INFECTIOUS disease transmission
Abstract

Mpox caught the attention of the general public following the global outbreak of clade IIb disease that began in 2022. This outbreak, predominantly due to human-to-human transmission of clade IIb infection, with a high proportion of cases occurring in men who have sex with men, led to the World Health Organization (WHO) classifying it as a public health emergency of international concern (PHEIC) from July 2022 to May 2023. A second PHEIC due to mpox was declared in August 2024 due to the increased spread of clade Ib disease in Africa, again related to an increase in cases due to sexual transmission. [ABSTRACT FROM AUTHOR]

Published
2024
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18. 8th IAS Conference on HIV Pathogenesis, Treatment & Prevention 19–22 July 2015, Vancouver, Canada

Author

Pate, Kelly Metcalf, Pohlmeyer, Chris, Walker‐Sperling, Victoria, Foote, Jeremy, Najarro, Kevin, Cryer, Catherine, Salgado, Maria, Gama, Lucio, Engle, Elizabeth, Shirk, Erin, Queen, Suzanne, Chioma, Stanley, Vermillion, Meghan, Bullock, Brandon, Li, Ming, Lyons, Claire, Adams, Robert, Zink, Chris, Clements, Janice, Mankowski, Joseph, Blankson, Joel, Micci, Luca, Ryan, Emily, Fromentin, Rémi, Benne, Clarisse, Chomont, Nicolas, Lifson, Jeffrey, Paiardini, Mirko, Lee, Sulggi, Fromentin, Remi, Silicano, Robert, Silicano, Janet, Richman, Douglas, O'Doherty, Una, Palmer, Sarah, Burbelo, Peter, Deeks, Steven, Ghneim, Khader, Ahlers, Jeff, Fourati, Slim, Shive, Carey, Cameron, Mark, Mukerjee, Pranab, Ghannoum, Mahmoud, Rodriguez, Benigno, Lederman, Michael, Sekaly, Rafick, Frange, Pierre, Faye, Albert, Avettand‐Fenoel, Veronique, Bellaton, Erainna, Deschamps, Diane, Angin, Mathieu, Caillat‐Zucman, Sophie, Peytavin, Gilles, Le Chenadec, Jerome, Warszawski, Josiane, Rouzioux, Christine, Saez‐Cirion, Asier, Cohort, ANRS Epf‐Co10 Pediatric, Chang, Christina, Cameron, Paul, Elliott, Julian, Perelson, Alan, Roche, Michael, Dantanarayana, Ashanti, Solomon, Ajantha, Naranbhai, Vivek, Tenakoon, Surekha, Hoh, Rebecca, McMahon, James, Sikaris, Ken, Hartogensis, Wendy, Bacchetti, Peter, Hecht, Frederick, Deeks, Steve, Lewin, Sharon, Byrareddy, Siddappa, Arthos, James, Cicala, Claudia, Reimann, Keith, Parslow, Tristram, Santangelo, Philip, Villinger, Francois, Fauci, Anthony, Ansari, Aftab, George, Michael, Weiser, Barbara, Burger, Harold, Lewy, Tyler, Anastos, Kathryn, Asmuth, David, Somsouk, Ma, Hunt, Peter, Min, Zhong, Miller, Christopher, and Li, Xiao Dong

Subjects
Mental Health, Digestive Diseases, Infectious Diseases, Pediatric AIDS, Bioengineering, Prevention, Clinical Research, Genetics, Health Services, Pediatric, Behavioral and Social Science, HIV/AIDS, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Infection, Reproductive health and childbirth, Good Health and Well Being, Clinical Sciences, Public Health and Health Services, Other Medical and Health Sciences
Published
2015

19. 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015).

Author

Pate, Kelly Metcalf, Pohlmeyer, Chris, Walker-Sperling, Victoria, Foote, Jeremy, Najarro, Kevin, Cryer, Catherine, Salgado, Maria, Gama, Lucio, Engle, Elizabeth, Shirk, Erin, Queen, Suzanne, Chioma, Stanley, Vermillion, Meghan, Bullock, Brandon, Li, Ming, Lyons, Claire, Adams, Robert, Zink, Chris, Clements, Janice, Mankowski, Joseph, Blankson, Joel, Micci, Luca, Ryan, Emily, Fromentin, Rémi, Benne, Clarisse, Chomont, Nicolas, Lifson, Jeffrey, Paiardini, Mirko, Lee, Sulggi, Fromentin, Remi, Silicano, Robert, Silicano, Janet, Richman, Douglas, O'Doherty, Una, Palmer, Sarah, Burbelo, Peter, Deeks, Steven, Ghneim, Khader, Ahlers, Jeff, Fourati, Slim, Shive, Carey, Cameron, Mark, Mukerjee, Pranab, Ghannoum, Mahmoud, Rodriguez, Benigno, Lederman, Michael, Sekaly, Rafick, Frange, Pierre, Faye, Albert, Avettand-Fenoel, Veronique, Bellaton, Erainna, Deschamps, Diane, Angin, Mathieu, Caillat-Zucman, Sophie, Peytavin, Gilles, Le Chenadec, Jerome, Warszawski, Josiane, Rouzioux, Christine, Saez-Cirion, Asier, Chang, Christina, Cameron, Paul, Elliott, Julian, Perelson, Alan, Roche, Michael, Dantanarayana, Ashanti, Solomon, Ajantha, Naranbhai, Vivek, Tenakoon, Surekha, Hoh, Rebecca, McMahon, James, Sikaris, Ken, Hartogensis, Wendy, Bacchetti, Peter, Hecht, Frederick, Deeks, Steve, Lewin, Sharon, Byrareddy, Siddappa, Arthos, James, Cicala, Claudia, Reimann, Keith, Parslow, Tristram, Santangelo, Philip, Villinger, Francois, Fauci, Anthony, Ansari, Aftab, George, Michael, Weiser, Barbara, Burger, Harold, Lewy, Tyler, Anastos, Kathryn, Asmuth, David, Somsouk, Ma, Hunt, Peter, Min, Zhong, Miller, Christopher, Li, Xiao Dong, and Hinkle, John

Subjects
Clinical Sciences, Public Health and Health Services, Other Medical and Health Sciences
Published
2015

20. THE FIRST THREE MONTHS.

Author

FAUCI, ANTHONY

Subjects
*SCIENCE education, *TASK forces, *HUMAN services
Abstract

This article, titled "THE FIRST THREE MONTHS," provides an insider's perspective on the government's response to COVID-19. The author, Dr. Fauci, recounts his experiences and observations from the early days of the pandemic. He discusses challenges in monitoring the situation in China, the urgency to develop a vaccine using mRNA technology, and difficulties faced by the CDC in collecting accurate data and creating effective tests. The article also touches on the polarized environment and the author's interactions with President Trump. This article is an excerpt from Anthony Fauci's book, "On Call: A Doctor's Journey in Public Service." Fauci reflects on his experiences during the COVID-19 pandemic and the challenges he faced as a public health official advising President Trump. He discusses differences in approach between the administration and previous ones, including Vice President Pence's excessive praise for Trump. Fauci also addresses the controversy surrounding mask-wearing and the promotion of hydroxychloroquine as a treatment for COVID-19. He emphasizes the importance of scientific education and the need for civility and understanding to address the country's divisions. [Extracted from the article]

Published
2024

26. Anthony Fauci on Larry Kramer and Loving Difficult People

Author

Fauci, Anthony

Subjects
General interest
Abstract

Byline: Anthony Fauci I recently attended a memorial service for Larry Kramer, the award-winning playwright, author and provocative gay activist. It has been three years since Larry's death, and a [...]

Published
2023

33. The Challenges of an HIV Vaccine Enterprise

Author

Zinkernagel, Rolf M., Wolf, Hans, Klausner, Richard D., Fauci, Anthony S., Corey, Lawrence, Nabel, Gary J., Gayle, Helene, Berkley, Seth, Haynes, Barton F., Baltimore, David, Collins, Chris, Douglas, R. Gordon, Esparza, Jose, Francis, Donald P., Ganguly, N. K., Gerberding, Julie Louise, Johnson, Margaret I., Kazatchkine, Michel D., McMichael, Andrew J., Makgoba, Malegapuru W., Pantaleo, Giuseppe, Piot, Peter, Shao, Yiming, Tramont, Edmund, Varmus, Harold, and Wasserheit, Judith N.

Published
2004

36. The Need for a Global HIV Vaccine Enterprise

Author

Klausner, Richard D., Fauci, Anthony S., Corey, Lawrence, Nabel, Gary J., Gayle, Helene, Berkley, Seth, Haynes, Barton F., Baltimore, David, Collins, Chris, Douglas, R. Gordon, Esparza, Jose, Francis, Donald P., Ganguly, N. K., Gerberding, Julie Louise, Johnston, Margaret I., Kazatchkine, Michel D., McMichael, Andrew J., Makgoba, Malegapuru W., Pantaleo, Giuseppe, Piot, Peter, Shao, Yiming, Tramont, Edmund, Varmus, Harold, and Wasserheit, Judith N.

Published
2003

42. Short-Cycle Structured Intermittent Treatment of Chronic HIV Infection with Highly Active Antiretroviral Therapy: Effects on Virologic, Immunologic, and Toxicity Parameters

Author

Dybul, Mark, Chun, Tae-Wook, Yoder, Christian, Hidalgo, Bertha, Belson, Michael, Hertogs, Kurt, Larder, Brendan, Dewar, Robin L., Fox, Cecil H., Hallahan, Claire W., Justement, J. Shawn, Migueles, Stephen A., Metcalf, Julia A., Davey, Richard T., Daucher, Marybeth, Pandya, Punita, Baseler, Michael, Ward, Douglas J., and Fauci, Anthony S.

Published
2001

46. Akiko Iwasaki.

Author

FAUCI, ANTHONY, MCMULLEN, ERIN, Dickstein, Leslie, Mansoor, Sanya, Shah, Simmone, and Zorthian, Julia

Subjects
POST-acute COVID-19 syndrome, PATIENT experience, ACUTE diseases, PATIENTS' attitudes, NATURAL immunity
Abstract

This article from TIME Magazine highlights the work of Akiko Iwasaki, a renowned immunologist and Yale professor. Iwasaki's expertise in the regulation of the human immune system has allowed her to lead the way in understanding how it reacts to COVID-19 and the consequences of Long COVID. Her research on innate immunity, or how the immune system first responds to pathogens, is providing valuable insights into Long COVID and informing treatment strategies. Iwasaki's accomplishments have earned her recognition in the scientific community, and her advocacy for women and people of color in science has had a positive impact on the field. [Extracted from the article]

Published
2024

48. HIV-1 and T Cell Dynamics after Interruption of Highly Active Antiretroviral Therapy (HAART) in Patients with a History of Sustained Viral Suppression

Author

Davey,, Richard T., Bhat, Niranjan, Yoder, Christian, Chun, Tae-Wook, Metcalf, Julia A., Dewar, Robin, Natarajan, Ven, Lempicki, Richard A., Adelsberger, Joseph W., Miller, Kirk D., Kovacs, Joseph A., Polis, Michael A., Walker, Robert E., Falloon, Judith, Masur, Henry, Gee, Dennis, Baseler, Michael, Dimitrov, Dimiter S., Fauci, Anthony S., and Lane, H. Clifford

Published
1999

50. Ending the HIV/AIDS Pandemic

Author

Eisinger, Robert Walter and Fauci, Anthony S.

Subjects
United States. National Institutes of Health, AIDS vaccines -- Research, Epidemics -- Research -- Care and treatment -- Prevention, HIV -- Research -- Care and treatment -- Prevention, Medical research, Health
Abstract

Ending the HIV/AIDS pandemic continues to represent a realistic goal that demands that we address numerous considerations and obstacles at the local, regional, national, and global levels. One can view [...]

Published
2018
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