7 results on '"Fatima Anwer"'
Search Results
2. Arrhythmic mitral valve prolapse: Diagnostic parameters for high‐risk patients: A systematic review and meta‐analysis
- Author
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Fatima Anwer, Ana P Arcia Franchini, Fotios Kakargias, Priyanka Panday, Pousette Hamid, Beshoy Iskander, and Federico Oliveri
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medicine.medical_specialty ,Mitral Valve Prolapse ,High risk patients ,business.industry ,Arrhythmias, Cardiac ,General Medicine ,Odds ratio ,medicine.disease ,QT interval ,Confidence interval ,Sudden cardiac death ,Relative risk ,Internal medicine ,Meta-analysis ,cardiovascular system ,medicine ,Cardiology ,Humans ,Mitral valve prolapse ,cardiovascular diseases ,Cardiology and Cardiovascular Medicine ,business - Abstract
BACKGROUND Although frequently considered a benign condition, new evidence has shown that mitral valve prolapse (MVP) is associated with complex ventricular arrhythmias (VAs) and sudden cardiac death (SCD). Therefore, we conducted a systematic review and meta-analysis of the relevant studies to investigate the parameters that could identify MVP patients at higher risk of experiencing complex VAs. METHOD We performed a systematic literature search of PubMed for potential studies between January 2010 and January 2021. Our meta-analysis included studies comparing MVP patients with complex VAs (A-MVP) and those without (NA-MVP). We used the fixed-effects model to obtain the odds ratio (OR), risk ratio (RR), or mean difference (MD) and 95% confidence interval (CI) for each analyzed parameter. RESULTS Six studies with 848 individuals were included in the meta-analysis. As compared to the NA-MVP patients, A-MVP patients had a higher prevalence of inverted T-wave (OR: 2.73; 95% CI: 1.85-4.02; p
- Published
- 2021
3. The Role of Chlamydia Trachomatis in the Pathogenesis of Cervical Cancer
- Author
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Ana P Arcia Franchini, Beshoy Iskander, Fatima Anwer, Federico Oliveri, Kakargias Fotios, Priyanka Panday, and Pousette Hamid
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General Engineering - Abstract
Chlamydia trachomatis (CT) is an obligate intracellular, Gram-negative bacterium that causes a variety of infections in both humans and animals. It is the causative agent of one of the most common sexually transmitted infections (STIs) with sequelae such as pelvic inflammatory disease, ectopic pregnancy, and infertility. Furthermore, Chlamydia infections have been epidemiologically linked to cervical cancer (CC) in patients with human papillomavirus (HPV) coinfection. However, a molecular mechanism linking Chlamydia to CC is yet to be established, and we still do not know if more aggressive diagnosis and treatment of Chlamydia could possibly lead to lower incidences of CC and associated mortality. Since CC is a leading cause of death among women worldwide, and HPV infection alone is insufficient to cause cancer, our goal was to determine the link between Chlamydia, HPV, and CC. This literature review aimed to understand the pathologic model of CC and how Chlamydia might induce or promote carcinogenesis alone or alongside HPV. In addition, we compared multiple studies attempting to associate Chlamydial infection with CC in different populations and aimed to determine whether there is an epidemiological correlation or not.
- Published
- 2022
4. Post-Traumatic Seizures: A Deep-Dive Into Pathogenesis
- Author
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Federico Oliveri, Priyanka Panday, Fatima Anwer, Beshoy Iskander, Pousette Hamid, Fotios Kakargias, and Ana P Arcia Franchini
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medicine.medical_specialty ,motor vehicle accident and epilepsy ,post-traumatic epilepsy ,030204 cardiovascular system & hematology ,Pathogenesis ,head injury and epilepsy ,03 medical and health sciences ,Epilepsy ,Post-traumatic seizure ,0302 clinical medicine ,Concussion ,Internal Medicine ,Pathology ,Medicine ,Post-traumatic epilepsy ,Intensive care medicine ,trauma and epilepsy ,business.industry ,General Engineering ,post-traumatic seizure ,medicine.disease ,brain injury and seizure ,Neurology ,Narrative review ,medicine.symptom ,business ,Deep dive ,030217 neurology & neurosurgery - Abstract
Post-traumatic seizures (PTS) have become an emerging challenge for neurologists worldwide with the rise of brain injuries. Trauma can lead to various outcomes, ranging from naive spasms to debilitating post-traumatic epilepsy (PTE). In this article, we will explore the pathogenesis of convulsions following a concussion. We will look at multiple studies to explain the various structural, metabolic, and inflammatory changes leading to seizures. Additionally, we will explore the association between severity and location of injury and PTE. PTE's pathophysiology is not entirely implicit, and we are still in the dark as to which anti-epileptic drugs will be useful in circumventing these attacks. The purpose of this narrative review is to explain the post-traumatic brain changes in detail so that such attacks can be either thwarted or treated more resourcefully in the future.
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- 2021
5. Subclinical Hypothyroidism in Geriatric Population and Its Association With Heart Failure
- Author
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Federico Oliveri, Beshoy Iskander, Fatima Anwer, Fotios Kakargias, Priyanka Panday, Ana P Arcia Franchini, and Pousette Hamid
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geriatric population ,Pediatrics ,medicine.medical_specialty ,thyroid dysfunction ,levothyroxine ,elderly population ,Cardiology ,Levothyroxine ,heart failure ,030204 cardiovascular system & hematology ,law.invention ,03 medical and health sciences ,High morbidity ,0302 clinical medicine ,Randomized controlled trial ,Geriatric population ,law ,Elderly population ,Internal Medicine ,medicine ,Subclinical infection ,business.industry ,Incidence (epidemiology) ,Endocrinology/Diabetes/Metabolism ,General Engineering ,medicine.disease ,subclinical hypothyroidism ,Heart failure ,heart failure prognosis ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Heart failure (HF) is one of the most common causes of hospitalization in the geriatric age group, above 65 years. It is associated with high morbidity, mortality, and bad prognosis. Subclinical hypothyroidism (SCH) is a common condition present in this age group that significantly affects the cardiovascular system. Thus, this review attempts to elaborate on the association between subclinical hypothyroidism and heart failure in terms of their prevalence, pathogenesis, prognosis, and possible management in a geriatric age group. Among the various published literature on this topic on PubMed, PubMed Central, and Google Scholar, 36 relevant studies were selected to correlate this association. We found that both SCH and HF can be present concurrently in this age group. Especially in the geriatric population with thyroid-stimulating hormone (TSH) higher than ten mIu/L, there is an increased incidence of heart failure and a worse prognosis with preexisting heart failure. However, randomized controlled trials will be needed to explore further whether treatment is warranted or not in this age group.
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- 2021
6. An Overview of Therapeutic Options in Relapsing-remitting Multiple Sclerosis
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Sidra Saleem, Fatima Anwer, Muniba Fayyaz, Arsalan Anwar, and Faria Anwar
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Oncology ,medicine.medical_specialty ,medicine.drug_class ,relapsing remitting multiple sclerosis ,Inflammation ,030204 cardiovascular system & hematology ,Monoclonal antibody ,Allergy/Immunology ,Pathogenesis ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Immune system ,Internal medicine ,Pathology ,therapeutics ,medicine ,Glatiramer acetate ,business.industry ,Multiple sclerosis ,General Engineering ,deep brain lesions ,autoimmune ,medicine.disease ,Siponimod ,Neurology ,chemistry ,demyelination ,Stem cell ,medicine.symptom ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Multiple sclerosis (MS) is a chronic disorder of the central nervous system (CNS). MS affects 2.1 million individuals every year and is also considered a major cause of economic health burden around the world. Genetics and environmental factors both play a role in the pathogenesis of MS by activating the immune response and causing inflammation. Patients with MS can have various clinical courses, but the most common pattern seen is relapsing-remitting multiple sclerosis (RRMS). Multiple therapeutic options have been studied to prevent RRMS patients from frequent relapses. The oldest and most frequently used medication for MS is interferon beta, either used alone or as add-on therapy with other drugs. Newer treatment options that have been recently approved to control MS symptoms and suppress the inflammation are glatiramer acetate and siponimod. Infusion therapies consisting of monoclonal antibodies and immunosuppressive drugs have also been studied in the recent past. Some trials have been conducted on the use of stem cells for RRMS patients. We have briefly discussed all treatment options and the response of RRMS patients in multiple trials.
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- 2019
7. The Effect of Physical Activity in Parkinson’s Disease: A Mini-Review
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Ibrar Anjum, Fatima Anwer, Ahsan Zil-E-Ali, Syeda S Jaffery, and Muniba Fayyaz
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0301 basic medicine ,medicine.medical_specialty ,Constipation ,Parkinson's disease ,business.industry ,Osteoporosis ,General Engineering ,Disease ,medicine.disease ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Mood ,Physical medicine and rehabilitation ,Quality of life ,medicine ,Apathy ,medicine.symptom ,business ,030217 neurology & neurosurgery ,Depression (differential diagnoses) - Abstract
This article will discuss the effects of physical activity in patients with Parkinson's disease. Presently, the motor and non-motor symptoms are difficult to treat with the current treatment of Parkinson's; therefore, as an adjuvant to the current treatment physical activity, has been recommended. Physical activity has been known to improve many symptoms in patients with Parkinson's disease. Some of these symptoms include the physical capacities, physical and cognitive functional capacities. Physical activity also slows the disease process, decreases the pain associated with Parkinson`s disease, prolongs the independent mobility (gait, balance, strength) and improves sleep, mood, memory hence improving the overall quality of life. Furthermore, physical activity has the potential to improve the non-motor symptoms (depression, apathy, fatigue, constipation) and the secondary complications of immobility (cardiovascular, osteoporosis) in Parkinson's disease.
- Published
- 2018
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