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Arrhythmic mitral valve prolapse: Diagnostic parameters for high‐risk patients: A systematic review and meta‐analysis
- Source :
- Pacing and Clinical Electrophysiology. 44:1746-1755
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- BACKGROUND Although frequently considered a benign condition, new evidence has shown that mitral valve prolapse (MVP) is associated with complex ventricular arrhythmias (VAs) and sudden cardiac death (SCD). Therefore, we conducted a systematic review and meta-analysis of the relevant studies to investigate the parameters that could identify MVP patients at higher risk of experiencing complex VAs. METHOD We performed a systematic literature search of PubMed for potential studies between January 2010 and January 2021. Our meta-analysis included studies comparing MVP patients with complex VAs (A-MVP) and those without (NA-MVP). We used the fixed-effects model to obtain the odds ratio (OR), risk ratio (RR), or mean difference (MD) and 95% confidence interval (CI) for each analyzed parameter. RESULTS Six studies with 848 individuals were included in the meta-analysis. As compared to the NA-MVP patients, A-MVP patients had a higher prevalence of inverted T-wave (OR: 2.73; 95% CI: 1.85-4.02; p
- Subjects :
- medicine.medical_specialty
Mitral Valve Prolapse
High risk patients
business.industry
Arrhythmias, Cardiac
General Medicine
Odds ratio
medicine.disease
QT interval
Confidence interval
Sudden cardiac death
Relative risk
Internal medicine
Meta-analysis
cardiovascular system
medicine
Cardiology
Humans
Mitral valve prolapse
cardiovascular diseases
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 15408159 and 01478389
- Volume :
- 44
- Database :
- OpenAIRE
- Journal :
- Pacing and Clinical Electrophysiology
- Accession number :
- edsair.doi.dedup.....fa8fda70c7c11c48e3f61f6af42f63f5