1. Fabrication of cinnamon essential oil nanoemulsions with high antibacterial activities via microfluidization.
- Author
-
Xing Z, Xu Y, Feng X, Gao C, Wu D, Cheng W, Meng L, Wang Z, Xu T, and Tang X
- Subjects
- Particle Size, Oils, Volatile chemistry, Oils, Volatile pharmacology, Anti-Bacterial Agents pharmacology, Anti-Bacterial Agents chemistry, Emulsions chemistry, Emulsions pharmacology, Cinnamomum zeylanicum chemistry, Staphylococcus aureus drug effects, Staphylococcus aureus growth & development, Escherichia coli drug effects, Escherichia coli growth & development
- Abstract
The high volatility and hydrophobicity of cinnamon essential oils (CiEO) limited their practical application. To enhance their stability and antibacterial activity, nanoemulsions encapsulating CiEO were prepared using hydroxypropyl-β-cyclodextrin/lauroyl arginate (HPCD/LAE) inclusion complexes through high-pressure microfluidization (HPM). Effects of HPM parameters on the stability and antibacterial properties of nanoemulsion were investigated. Results revealed that increased processing pressure and cycle numbers were associated with reduced droplet size and greater homogeneity in CiEO distribution. Storage and thermal stability were optimized at 100 MPa and seven cycles. Moreover, the nanoemulsions showed strong synergistic antibacterial against E. coli (19.79 mm) and S. aureus (23.61 mm) compared with LAE (11.52 mm and 12.82 mm, respectively) and CiEO alone (13.26 mm and 17.68 mm, respectively). This study provided new information for constructing CiEO nanoemulsion, which is suitable for use in the food industry., Competing Interests: Declaration of competing interest The authors have no competing financial or personal interests., (Copyright © 2024 Elsevier Ltd. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF