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Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. Users will be able to bridge the knowledge gap that exists in the comprehensive coverage surrounding the epidemiology of endocrine tumors. Globally, the prevalence and incidence of endocrine tumors is high. This audience needs a treatise where they can gain a broad overview of endocrine tumors with a focus on epidemiology. - Supplies information about the epidemiology of various endocrine tumors, both benign and malignant, to endocrinologists, oncologists and related health care professionals - Focuses on the impact upon costs and patient deaths due to complications of these tumors - Describes how endocrine tumors affect various age groups and ethnicities, discussing the prevention of endocrine tumors - Presents chapters on Cancer Problem, Specific Endocrine Tumors, Prevention, Detection and Diagnosis, and Treatment of Endocrine Tumors - Provides review questions with an answer key and detailed glossary

Tumors and Cancers: Endocrine Glands – Blood – Marrow – Lymph provides succinct reviews of neoplastic growths disrupting normal functions of affected structures. Each chapter presents a state of the art summary of tumor/cancer of a particular type in relation to its biology, epidemiology, disease mechanisms, clinical signs, diagnosis, treatment and prognosis.

This comprehensive subspecialty reference book on NeuroEndocrine Tumor (NET) pathology brings together the diagnostic and clinical expertise of an outstanding team of practicing neuroendocrine pathologists and oncologists. In addition to in-depth coverage of clinico-pathologic aspects of NETs of the various organ systems, the recent histological grading and staging schemes proposed by the North American and European NeuroEndocrine Tumor Societies (NANETS, ENETS), the World Health Organization (WHO) and the American Joint Committee on Cancer (AJCC), this book also focuses on the recent molecular and therapeutic advances in the field of NET pathology and oncology. Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances will be an essential reference book for anatomic pathology (histopathology) residents, fellows, surgical pathologists, researchers, oncologists, surgeons and other medical professionals practicing advanced NET Pathology and Oncology in academia, community, private practice and research settings.

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Douglas L. Fraker, is devoted to Endocrine Tumors. Dr. Fraker has assembled expert authors to review the following topics: Management of thyroid nodular disease: Current cytopathology classifications and genetic testing; Surgical management of lymph node compartments in papillary thyroid cancer; Current guidelines for post-operative treatment and follow-up of well differentiated thyroid cancer; Outpatient thyroid surgery – is it safe?; Asymptomatic hyperparathyroidism- diagnostic pitfalls and surgical intervention; Intra-operative PTH monitoring: optimal utilization; Minimally invasive parathyroidectomy vs bilateral neck exploration for primary hyperparathyroidism; Pheochromocytoma and paraganglioma: Diagnosis, genetics, and treatment; Minimally invasive adrenalectomy; Treatment of adrenocortical cancinoma: benefits of aggressive surgery; Biochemical diagnosis and pre-operative imaging of gastro-intestinal neuroendocrine tumors; Minimally invasive techniques for resection of pancreatic neuroendocrine tumors; and Treatment of metastatic neuroendocrine tumors to the liver.

Patients with a variety of tumors present to the physician because of clinical manifestations of hormones secreted in excess. This phenomenon attracted the investigative interest of such pioneers as Harvey Cushing who recognized that pituitary tumors may cause acromegaly and Charles Mayo who associated hyper­ tension with adrenal medullary neoplasms. Current int~rest in endocrine-related tumors has intensified because of the explosive development of newer methodol­ ogy for their study. Specific measurements of secretory products, hybridization assays to identify products of genomic translation and quantitative assessment of tissue hormone receptors have provided means of characterizing and precisely following patients with endocrine-related tumors. Treatments based upon these advances are rapidly proliferating. The current volume attempts to synthesize much of this recent information with the goal of providing a sound basis for making clinical judgements regarding diagnosis and management. Tumors of endocrine glandular tissues commonly confront practicing physi­ cians with difficult management problems. Several unique features of these tumors necessitate collaboration among various specialty disciplines in order to resolve these problems and to provide a high level of clinical care. For example, endocrine neoplasms secrete active hormones or hormone precursors which produce clinical manifestations most familiar to endocrinologists. Certain thera­ pies such as radioactive iodine for thyroid cancer take advantage of the hormone­ responsiveness of these tumors to facilitate treatment. These aspects require individuals trained in endocrinology to implement complex diagnostic and thera­ peutic maneuvers.

The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. This book provides an up-to-date summaryfrom clinical basics and latest follow-up guidelines to the most recent molecular findings in multiple endocrine neoplasia Type I syndrome. Articles have been assembled by acknowledged experts in their respective fields to provide current perspectives on the clinical and genetic backgroundsofthis syndrome and to review carefully the latest discoveries concerning the possible functions and interactions ofmenin, the protein encoded by the MEN1gene,including itspossible role incell cycle regulation,hematopoiesis,and bone development. The goal ofthe book is also to present the most recent findings and the broadest aspects of the role of menin in tumorigenesis of the endocrine glands involved in MEN I syndrome (pituitary, parathyroid, endocrine pancreas and adrenal). The connection between the basic experimental and clinical points of view are highlighted through a discussion on animal models, which explores the field in both an inspiring and questioning manner with a focus on areas that remain to be clarified. Our goal was to bring together clinicians and basic researchers who represent a wide range of interests in this particular field of endocrine oncology. Presentingacomprehensive and current overviewofbasic experimental and clinical findings, this book can bring us closer to understanding endocrine tumorigenesis in multiple endocrine neoplasia Type I. Katalin Balogh, MD, PhD Attita Patocs, MD, MSc, PhD v ABOUT THEEDITORS...

A truly comprehensive reference for the management of patients with endocrine cancer The new edition of Clinical Endocrine Oncology has been fully revised and extended making it the most comprehensive and up-to-date reference available. Written and edited by leading international experts in the field, it sets the standard in multidisciplinary care for patients with endocrine tumors. The book provides specific and detailed guidance on the basic, clinical, investigative and therapeutic processes required for the thorough evaluation of a patient with a tumor in an endocrine organ. The eighty-four chapters are arranged in seven parts: • Endocrine Oncology and Therapeutic Options • Thyroid and Parathyroid Tumors • Pituitary and Hypothalamic Lesions • Adrenal and Gonadal Tumors • Neuroendocrine Tumors and the Clinical Syndromes • Medical Syndromes and Endocrine Neoplasia • Endocrine-responsive Tumors and Female Reproductive Hormone Therapy. This authoritative and practical text will be an invaluable resource for all those working in the field, including endocrinologists, medical oncologists, surgeons, radiation therapists, interventional radiologists, specialist nurses, and clinical scientists. John A.H. Wass is joined in this edition by a new editor, Ian D. Hay, Professor of Medicine and Endocrinology Research at the Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

Il y a peu d'ouvrages sur les tumeurs endocrines digestives et thoraciques. La complexité de leur prise en charge, souvent confiée à différents spécialistes, la multiplicité des terminologies utilisées pour les désigner, la diversité de leurs localisations et de leur caractérisation expliquent cette absence de travaux. Une synthèse des connaissances cliniques relatives à ces pathologies était donc nécessaire, exigence renforcée par l'arrivée de nouvelles techniques d'imagerie et de nouveaux traitements. Cet ouvrage fait le pari d'une approche transversale de l'étude de ces tumeurs tout en insistant sur leurs caractéristiques communes, une fois énoncées les caractéristiques cliniques et pronostiques, les auteurs étudient les différentes armes thérapeutiques. Cet ouvrage, fondé sur une approche multidisciplinaire, est un outil indispensable pour tout médecin non spécialiste cherchant à acquérir une base de connaissances dans ce domaine. Le lecteur sera, de plus, conquis par l'intérêt communicatif que portent les auteurs à l'étude de ces tumeurs si particulières.