40 results on '"Deshmukh, Sujal V."'
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2. Supplementary Figure 2 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
3. Supplementary Figure 4 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
4. Supplementary Figure 3 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
5. Supplementary Figure 5 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
6. Supplementary Methods, Table 1, Figure Legends 1-5 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
7. Supplementary Figure 1 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
8. Quantification of accurate composition and total abundance of homologous proteins by conserved-plus-surrogate peptide (CPSP) approach: Quantification of UDP glucuronosyltransferases in human tissues
9. siRNA-Mediated Knockdown of P450 Oxidoreductase in Rats: A Tool to Reduce Metabolism by CYPs and Increase Exposure of High Clearance Compounds
10. Direct determination of the ratio of unbound fraction in plasma to unbound fraction in microsomal system ( fup/ fumic) for refined prediction of phase I mediated metabolic hepatic clearance
11. Quantification of Accurate Composition and Total Abundance of Homologous Proteins by Conserved-Plus-Surrogate Peptide Approach: Quantification of UDP Glucuronosyltransferases in Human Tissues
12. The effect of opiates on the activity of human placental aromatase/CYP19
13. Methadone Metabolism by Early Gestational Age Placentas
14. The effect of methadone and buprenorphine on human placental aromatase
15. Bidirectional transfer of methadone across human placenta
16. Methadone metabolism by human placenta
17. N-Demethylation of levo-α-acetylmethadol by human placental aromatase
18. Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors
19. The Discovery of 3-((4-Chloro-3-methoxyphenyl)amino)-1-((3R,4S)-4-cyanotetrahydro-2H-pyran-3-yl)-1H-pyrazole-4-carboxamide, a Highly Ligand Efficient and Efficacious Janus Kinase 1 Selective Inhibitor with Favorable Pharmacokinetic Properties
20. Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys
21. Potent benzoazepinone γ-secretase modulators with improved bioavailability
22. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
23. The Discovery of 3-((4-Chloro-3-methoxyphenyl)amino)-1-((3R,4S)-4-cyanotetrahydro-2H-pyran-3-yl)-1H-pyrazole-4-carboxamide, a Highly Ligand Efficient and Efficacious Janus Kinase 1 Selective Inhibitor with Favorable Pharmacokinetic Properties
24. Discovery of 1-[3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron Dual Kinase Inhibitor with Preferential Affinity for the Activated State of c-Met
25. Discovery of a 5H-Benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer
26. Direct determination of the ratio of unbound fraction in plasma to unbound fraction in microsomal system (fup/fumic) for refined prediction of phase I mediated metabolic hepatic clearance
27. Clinical Drug–Drug Interactions
28. MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
29. Design of novel histone deacetylase inhibitors
30. Abstract C209: Inhibition of both c‐Met and EGFR signaling shows synergistic antitumor activity in non‐small cell lung cancer model
31. The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors
32. Clinical Drug‐Drug Interactions
33. Aromatase Is the Major Enzyme Metabolizing Buprenorphine in Human Placenta
34. Transfer of l-α-Acetylmethadol (LAAM) and l-α-Acetyl-N-normethadol (norLAAM) by the Perfused Human Placental Lobule
35. A Pharmacokinetic Modeling Approach to Predict the Contribution of Active Metabolites to Human Efficacious Dose
36. Discoveryof 1-[3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide(MK-8033): A Specific c-Met/Ron Dual Kinase Inhibitor withPreferential Affinity for the Activated State of c-Met.
37. Direct determination of the ratio of unbound fraction in plasma to unbound fraction in microsomal system (fu p/fu mic) for refined prediction of phase I mediated metabolic hepatic clearance
38. Validation of the use of nonnaive surgically catheterized rats for pharmacokinetics studies.
39. N-demethylation of levo-alpha-acetylmethadol by human placental aromatase.
40. Transfer of L-alpha-acetylmethadol (LAAM) and L-alpha-acetyl-N-normethadol (norLAAM) by the perfused human placental lobule.
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