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Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109 (USA), Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109 (USA) ; Department of Biological Chemistry, University of Michigan (USA), Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109 (USA) ; Department of Medicinal Chemistry, Department of Chemistry, Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109 (USA), Department of Biological Engineering, Inha University (Korea), Scaglione, Jamie, Akey, David, Sullivan, Rachel, Kittendorf, Jeffrey, Rath, Christopher, Kim, Eung-Soo, Smith, Janet, Sherman, David, Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109 (USA), Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109 (USA) ; Department of Biological Chemistry, University of Michigan (USA), Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109 (USA) ; Department of Medicinal Chemistry, Department of Chemistry, Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109 (USA), Department of Biological Engineering, Inha University (Korea), Scaglione, Jamie, Akey, David, Sullivan, Rachel, Kittendorf, Jeffrey, Rath, Christopher, Kim, Eung-Soo, Smith, Janet, and Sherman, David

Department of Chemistry and Biophysics, University of Michigan, 930 North University, Ann Arbor, MI 48109 (USA) ; These authors contributed equally to this work., Department of Chemistry and Biophysics, University of Michigan, 930 North University, Ann Arbor, MI 48109 (USA), Stelzer, Andrew, Kratz, Jeremy, Zhang, Qi, Al-Hashimi, Hashim, Department of Chemistry and Biophysics, University of Michigan, 930 North University, Ann Arbor, MI 48109 (USA) ; These authors contributed equally to this work., Department of Chemistry and Biophysics, University of Michigan, 930 North University, Ann Arbor, MI 48109 (USA), Stelzer, Andrew, Kratz, Jeremy, Zhang, Qi, and Al-Hashimi, Hashim

Macromolecular Science and Engineering, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA) ; Michigan Nanotechnology, Institute for Medicine and Biological Sciences, University of Michigan, 9220 MSRB III, 1150 West Medical Center Dr. Ann Arbor, MI 48109 (USA), Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA), Fax: (+1)???734-763-2283, Michigan Nanotechnology, Institute for Medicine and Biological Sciences, University of Michigan, 9220 MSRB III, 1150 West Medical Center Dr. Ann Arbor, MI 48109 (USA), Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA), Fax: (+1)???734-763-2283 ; Macromolecular Science and Engineering, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA) ; Michigan Nanotechnology, Institute for Medicine and Biological Sciences, University of Michigan, 9220 MSRB III, 1150 West Medical Center Dr. Ann Arbor, MI 48109 (USA), Mullen, Douglas G., Borgmeier, Emilee L., Desai, Ankur M., Van Dongen, Mallory A., Barash, Mark, Cheng, Xue-min, Baker, James R., Banaszak Holl, Mark M., Macromolecular Science and Engineering, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA) ; Michigan Nanotechnology, Institute for Medicine and Biological Sciences, University of Michigan, 9220 MSRB III, 1150 West Medical Center Dr. Ann Arbor, MI 48109 (USA), Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA), Fax: (+1)???734-763-2283, Michigan Nanotechnology, Institute for Medicine and Biological Sciences, University of Michigan, 9220 MSRB III, 1150 West Medical Center Dr. Ann Arbor, MI 48109 (USA), Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA), Fax: (+1)???734-763-2283 ; Macromolecular Science and Engineering, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA) ; Michigan Nanotechnology, Institute for Medicine and Biological Sciences, University of Michigan, 9220 MSRB III, 1150 West Medical Center Dr. Ann Arbor, MI 48109 (USA), Mullen, Douglas G., Borgmeier, Emilee L., Desai, Ankur M., Van Dongen, Mallory A., Barash, Mark, Cheng, Xue-min, Baker, James R., and Banaszak Holl, Mark M.

Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109, USA ; Amgen Inc., Chemistry Research and Discovery, Analytical Chemistry, One Amgen Center Drive, Mail Stop 25-2-A, Thousand Oaks, CA 91 320., Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109, USA, Department of Pathology, The University of Michigan Medical Center, Ann Arbor, MI 48109, USA, Department of Surgery, The University of Michigan Medical Center, Ann Arbor, MI 48109, USA ; Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109, USA ; Department of Pathology, The University of Michigan Medical Center, Ann Arbor, MI 48109, USA ; Comprehensive Cancer Center, The University of Michigan Medical Center, Ann Arbor, MI 48109, USA ; University of Michigan Medical Center, Department of Surgery, MSRBI, A510B, Box 0658, Ann Arbor, MI 48109, USA., Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA, Department of Chemistry, Instrumental Analysis and Bioanalysis, Saarland University, 66123 Saarbrucken, Germany, Yoo, Chul, Patwa, Tasneem H., Kreunin, Paweena, Miller, Fred R., Huber, Christian G., Nesvizhskii, Alexey I., Lubman, David M., Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109, USA ; Amgen Inc., Chemistry Research and Discovery, Analytical Chemistry, One Amgen Center Drive, Mail Stop 25-2-A, Thousand Oaks, CA 91 320., Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109, USA, Department of Pathology, The University of Michigan Medical Center, Ann Arbor, MI 48109, USA, Department of Surgery, The University of Michigan Medical Center, Ann Arbor, MI 48109, USA ; Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109, USA ; Department of Pathology, The University of Michigan Medical Center, Ann Arbor, MI 48109, USA ; Comprehensive Cancer Center, The University of Michigan Medical Center, Ann Arbor, MI 48109, USA ; University of Michigan Medical Center, Department of Surgery, MSRBI, A510B, Box 0658, Ann Arbor, MI 48109, USA., Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA, Department of Chemistry, Instrumental Analysis and Bioanalysis, Saarland University, 66123 Saarbrucken, Germany, Yoo, Chul, Patwa, Tasneem H., Kreunin, Paweena, Miller, Fred R., Huber, Christian G., Nesvizhskii, Alexey I., and Lubman, David M.

Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA, Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA ; Department of Pharmacology, University of Michigan, Ann Arbor, MI, 48109, USA ; Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109-1055, USA., HELD/TMBB, Centers for Disease Control and Prevention, Morgantown, West Virginia 26505, USA, Wei, Hui, Dean, Stacey L., Parkin, Mark C., Nolkrantz, Kerstin, O'Callaghan, James P., Kennedy, Robert T., Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA, Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA ; Department of Pharmacology, University of Michigan, Ann Arbor, MI, 48109, USA ; Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109-1055, USA., HELD/TMBB, Centers for Disease Control and Prevention, Morgantown, West Virginia 26505, USA, Wei, Hui, Dean, Stacey L., Parkin, Mark C., Nolkrantz, Kerstin, O'Callaghan, James P., and Kennedy, Robert T.

Semiconductor Electronics Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA ; WILEY-VCH Verlag Berlin ; Department of Chemistry, Rutgers University, Piscataway, NJ 08854, USA Semiconductor Electronics Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA Department of Physics and Astronomy, Rutgers University, Piscataway, NJ 08854, USA IBM T. J. Watson Research Center, Yorktown Heights, New York, USA Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, Department of Physics and Astronomy, Rutgers University, Piscataway, NJ 08854, USA, IBM T. J. Watson Research Center, Yorktown Heights, New York, USA, Department of Chemistry, Rutgers University, Piscataway, NJ 08854, USA, Sayan, S., Bartynski, R. A., Zhao, X., Gusev, E. P., Vanderbilt, D., Croft, M., Banaszak Holl, Mark M., Garfunkel, E., Semiconductor Electronics Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA ; WILEY-VCH Verlag Berlin ; Department of Chemistry, Rutgers University, Piscataway, NJ 08854, USA Semiconductor Electronics Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA Department of Physics and Astronomy, Rutgers University, Piscataway, NJ 08854, USA IBM T. J. Watson Research Center, Yorktown Heights, New York, USA Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, Department of Physics and Astronomy, Rutgers University, Piscataway, NJ 08854, USA, IBM T. J. Watson Research Center, Yorktown Heights, New York, USA, Department of Chemistry, Rutgers University, Piscataway, NJ 08854, USA, Sayan, S., Bartynski, R. A., Zhao, X., Gusev, E. P., Vanderbilt, D., Croft, M., Banaszak Holl, Mark M., and Garfunkel, E.

Department of Chemistry and the Macromolecular Research Center, The University of Michigan, 48109, Ann Arbor, MI, USA, Department of Chemistry and the Macromolecular Research Center, The University of Michigan, 48109, Ann Arbor, MI, USA; Department of Chemistry, Tuskegee Institute, 36088, Tuskegee, Alabama, USA, Ann Arbor, Kikyotani, S., Ludwick, Adriane G., Brandt, K.A., Overberger, C.G., Department of Chemistry and the Macromolecular Research Center, The University of Michigan, 48109, Ann Arbor, MI, USA, Department of Chemistry and the Macromolecular Research Center, The University of Michigan, 48109, Ann Arbor, MI, USA; Department of Chemistry, Tuskegee Institute, 36088, Tuskegee, Alabama, USA, Ann Arbor, Kikyotani, S., Ludwick, Adriane G., Brandt, K.A., and Overberger, C.G.

Department of Biology, The University of Michigan, 48109, Ann Arbor, MI, USA, Department of Chemistry, The University of Michigan, 48109, Ann Arbor, MI, USA, Department of Biology, The University of Michigan, 48109, Ann Arbor, MI, USA; Department of Chemistry, The University of Michigan, 48109, Ann Arbor, MI, USA, Ann Arbor, Betts, Scott D., Hachigian, Todd M., Pichersky, Eran, Yocum, Charles F., Department of Biology, The University of Michigan, 48109, Ann Arbor, MI, USA, Department of Chemistry, The University of Michigan, 48109, Ann Arbor, MI, USA, Department of Biology, The University of Michigan, 48109, Ann Arbor, MI, USA; Department of Chemistry, The University of Michigan, 48109, Ann Arbor, MI, USA, Ann Arbor, Betts, Scott D., Hachigian, Todd M., Pichersky, Eran, and Yocum, Charles F.

Biophysics Research Division, The University of Michigan, 930 North University Avenue, 48109, Ann Arbor, MI, USA; Department of Biological Chemistry, The University of Michigan, 930 North University Avenue, 48109, Ann Arbor, MI, USA, Biophysics Research Division, The University of Michigan, 930 North University Avenue, 48109, Ann Arbor, MI, USA; Department of Biological Chemistry, The University of Michigan, 930 North University Avenue, 48109, Ann Arbor, MI, USA; Institut de Biologie Structurale-Jean-Pierre Ebel, Grenoble, France, Ann Arbor, Zuiderweg, Erik R.P., Zeng, Lei, Brutscher, Bernhard, Morshauser, Robert C., Biophysics Research Division, The University of Michigan, 930 North University Avenue, 48109, Ann Arbor, MI, USA; Department of Biological Chemistry, The University of Michigan, 930 North University Avenue, 48109, Ann Arbor, MI, USA, Biophysics Research Division, The University of Michigan, 930 North University Avenue, 48109, Ann Arbor, MI, USA; Department of Biological Chemistry, The University of Michigan, 930 North University Avenue, 48109, Ann Arbor, MI, USA; Institut de Biologie Structurale-Jean-Pierre Ebel, Grenoble, France, Ann Arbor, Zuiderweg, Erik R.P., Zeng, Lei, Brutscher, Bernhard, and Morshauser, Robert C.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Fax: Int. code +(313)936-7628, e-mail: vlpec@umich.edu, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Fax: Int. code +(313)936-7628, e-mail: vlpec@umich.edu ; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Fax: Int. code +(313)936-7628, e-mail: vlpec@umich.edu, Stemmler, Ann J., Kampf, Jeffrey W., Pecoraro, Vincent L., Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Fax: Int. code +(313)936-7628, e-mail: vlpec@umich.edu, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Fax: Int. code +(313)936-7628, e-mail: vlpec@umich.edu ; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Fax: Int. code +(313)936-7628, e-mail: vlpec@umich.edu, Stemmler, Ann J., Kampf, Jeffrey W., and Pecoraro, Vincent L.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA, Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA ; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, College of Veterinary Medicine, Michigan State University, East Lansing, MI 68824, USA, Srinivasan, Jannavi R., Liu, Yan-hui, Venta, Patrick J., Siemieniak, David, Killeen, Anthony A., Zhu, Yongdong, Lubman, David M., Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA, Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA ; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, College of Veterinary Medicine, Michigan State University, East Lansing, MI 68824, USA, Srinivasan, Jannavi R., Liu, Yan-hui, Venta, Patrick J., Siemieniak, David, Killeen, Anthony A., Zhu, Yongdong, and Lubman, David M.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 USA, Department of Biology, University of Michigan, Ann Arbor, MI 48109 USA, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 USA; Department of Biology, University of Michigan, Ann Arbor, MI 48109 USA, Riggs, Pamela J., Mei, Rui, Yocum, Charles F., Penner-Hahn, James E., Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 USA, Department of Biology, University of Michigan, Ann Arbor, MI 48109 USA, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 USA; Department of Biology, University of Michigan, Ann Arbor, MI 48109 USA, Riggs, Pamela J., Mei, Rui, Yocum, Charles F., and Penner-Hahn, James E.

Department of Pharmacology, The University of Michigan, Ann Arbor, MI 48109, U.S.A., Department of Medicinal Chemistry, The University of Michigan, Ann Arbor, MI 48109, U.S.A., Department of Internal Medicine, The University of Michigan, Ann Arbor, MI 48109, U.S.A., Department of Pharmacology, The University of Michigan, Ann Arbor, MI 48109, U.S.A.; Department of Medicinal Chemistry, The University of Michigan, Ann Arbor, MI 48109, U.S.A., Division of Nuclear Medicine, VA Medical Center, Ann Arbor, MI 48109, U.S.A., Plotzke, Kathleen P., Haradahira, Terushi, Stancato, Louis F., Olken, Norman M., Skinner, Scott, Gross, Milton D., Wahl, Richard L., Counsell, Raymond E., Department of Pharmacology, The University of Michigan, Ann Arbor, MI 48109, U.S.A., Department of Medicinal Chemistry, The University of Michigan, Ann Arbor, MI 48109, U.S.A., Department of Internal Medicine, The University of Michigan, Ann Arbor, MI 48109, U.S.A., Department of Pharmacology, The University of Michigan, Ann Arbor, MI 48109, U.S.A.; Department of Medicinal Chemistry, The University of Michigan, Ann Arbor, MI 48109, U.S.A., Division of Nuclear Medicine, VA Medical Center, Ann Arbor, MI 48109, U.S.A., Plotzke, Kathleen P., Haradahira, Terushi, Stancato, Louis F., Olken, Norman M., Skinner, Scott, Gross, Milton D., Wahl, Richard L., and Counsell, Raymond E.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA, Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA:Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA, Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA, Li, I-Chian, Blake, Diane A., Goldstein, Irwin J., Chu, Ernest H.Y., Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA, Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA:Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA, Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA, Li, I-Chian, Blake, Diane A., Goldstein, Irwin J., and Chu, Ernest H.Y.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Borovika, Alina, Tang, Pui???in, Klapman, Seth, Nagorny, Pavel, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Borovika, Alina, Tang, Pui???in, Klapman, Seth, and Nagorny, Pavel

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109???1055 (USA) http://www.umich.edu/???jmgroup, Partridge, Katherine M., Bader, Scott J., Buchan, Zachary A., Taylor, Christopher E., Montgomery, John, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109???1055 (USA) http://www.umich.edu/???jmgroup, Partridge, Katherine M., Bader, Scott J., Buchan, Zachary A., Taylor, Christopher E., and Montgomery, John

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Mensah, Enoch, Camasso, Nicole, Kaplan, Will, Nagorny, Pavel, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Mensah, Enoch, Camasso, Nicole, Kaplan, Will, and Nagorny, Pavel

Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109 (USA), Speelman, Amy L., Lehnert, Nicolai, Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109 (USA), Speelman, Amy L., and Lehnert, Nicolai

Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), Babij, Nicholas R., Wolfe, John P., Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), Babij, Nicholas R., and Wolfe, John P.

Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109???1055 (USA), Han, Linjie, Ruotolo, Brandon T., Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109???1055 (USA), Han, Linjie, and Ruotolo, Brandon T.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, McQuarters, Ashley B., Goodrich, Lauren E., Goodrich, Claire M., Lehnert, Nicolai, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, McQuarters, Ashley B., Goodrich, Lauren E., Goodrich, Claire M., and Lehnert, Nicolai

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109???1055 (USA), Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen (Denmark), Department of Chemistry, Western Michigan University, Kalamazoo, MI 49008???5413 (USA), On leave from: Faculty of Chemistry, University of Wroc??aw, 14 Joliot???Curie, 50???383 Wroc??aw (Poland), ??uczkowski, Marek, Zeider, Brian A., Hinz, Alia V. H., Stachura, Monika, Chakraborty, Saumen, Hemmingsen, Lars, Huffman, David L., Pecoraro, Vincent L., Department of Chemistry, University of Michigan, Ann Arbor, MI 48109???1055 (USA), Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen (Denmark), Department of Chemistry, Western Michigan University, Kalamazoo, MI 49008???5413 (USA), On leave from: Faculty of Chemistry, University of Wroc??aw, 14 Joliot???Curie, 50???383 Wroc??aw (Poland), ??uczkowski, Marek, Zeider, Brian A., Hinz, Alia V. H., Stachura, Monika, Chakraborty, Saumen, Hemmingsen, Lars, Huffman, David L., and Pecoraro, Vincent L.

Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA), Manchester Institute of Biotechnology and Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN (UK), Khara, Basile, Menon, Navya, Levy, Colin, Mansell, David, Das, Debasis, Marsh, E. Neil G., Leys, David, Scrutton, Nigel S., Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA), Manchester Institute of Biotechnology and Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN (UK), Khara, Basile, Menon, Navya, Levy, Colin, Mansell, David, Das, Debasis, Marsh, E. Neil G., Leys, David, and Scrutton, Nigel S.

Department of Chemistry and the Macromolecular Engineering Program, University of Michigan, Ann Arbor, MI 48109???1055 (USA), Landenberger, Kira B., Bolton, Onas, Matzger, Adam J., Department of Chemistry and the Macromolecular Engineering Program, University of Michigan, Ann Arbor, MI 48109???1055 (USA), Landenberger, Kira B., Bolton, Onas, and Matzger, Adam J.

Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA), Department of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK 73019 (USA) http://nitroso.ou.edu, Xu, Nan, Goodrich, Lauren E., Lehnert, Nicolai, Powell, Douglas R., Richter???addo, George B., Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, MI 48109 (USA), Department of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK 73019 (USA) http://nitroso.ou.edu, Xu, Nan, Goodrich, Lauren E., Lehnert, Nicolai, Powell, Douglas R., and Richter???addo, George B.

Life Sciences Institute, Departments of Medicinal Chemistry, Chemistry, and Microbiology and Immunology, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, MI 48109???2216 (USA), Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 189 Songling Road, Qingdao, Shandong 266101 (P. R. China), School of Medicine and Health Sciences, University of Papua New Guinea, P.???O. Box 5623, Boroko, NCD (Papua New Guinea), Zhang, Wei, Fortman, Jeffrey L., Carlson, Jacob C., Yan, Jinyong, Liu, Yi, Bai, Fali, Guan, Wenna, Jia, Junyong, Matainaho, Teatulohi, Sherman, David H., Li, Shengying, Life Sciences Institute, Departments of Medicinal Chemistry, Chemistry, and Microbiology and Immunology, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, MI 48109???2216 (USA), Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 189 Songling Road, Qingdao, Shandong 266101 (P. R. China), School of Medicine and Health Sciences, University of Papua New Guinea, P.???O. Box 5623, Boroko, NCD (Papua New Guinea), Zhang, Wei, Fortman, Jeffrey L., Carlson, Jacob C., Yan, Jinyong, Liu, Yi, Bai, Fali, Guan, Wenna, Jia, Junyong, Matainaho, Teatulohi, Sherman, David H., and Li, Shengying

Departments of Pathology, Biological Chemistry and the Interdisciplinary Program in Medicinal Chemistry, The Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109???2216, USA, Makley, Leah N., Gestwicki, Jason E., Departments of Pathology, Biological Chemistry and the Interdisciplinary Program in Medicinal Chemistry, The Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109???2216, USA, Makley, Leah N., and Gestwicki, Jason E.

Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), Wolfe, John P., Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), and Wolfe, John P.

Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), Hopkins, Brett A., Wolfe, John P., Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), Hopkins, Brett A., and Wolfe, John P.

Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), Wolfe, John P., Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), and Wolfe, John P.

Life Sciences Institute and Departments of Medicinal Chemistry, Microbiology & Immunology, and Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Department of Chemistry, Colorado State University, Fort Collins, CO 80523 (USA), The University of Colorado Cancer Center, Aurora, CO 80045 (USA) http://rwindigo1.chm.colostate.edu/, Department of Ecology and Evolution, University of Chicago, 1101 East 57th Street, Chicago, IL 60637 (USA), Finefield, Jennifer M., Sherman, David H., Kreitman, Martin, Williams, Robert M., Life Sciences Institute and Departments of Medicinal Chemistry, Microbiology & Immunology, and Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Department of Chemistry, Colorado State University, Fort Collins, CO 80523 (USA), The University of Colorado Cancer Center, Aurora, CO 80045 (USA) http://rwindigo1.chm.colostate.edu/, Department of Ecology and Evolution, University of Chicago, 1101 East 57th Street, Chicago, IL 60637 (USA), Finefield, Jennifer M., Sherman, David H., Kreitman, Martin, and Williams, Robert M.

Life Sciences Institute and Departments of Medicinal Chemistry, Microbiology & Immunology, and Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Department of Chemistry, Colorado State University, Fort Collins, CO 80523 (USA), The University of Colorado Cancer Center, Aurora, CO 80045 (USA) http://rwindigo1.chm.colostate.edu/, Department of Ecology and Evolution, University of Chicago, 1101 East 57th Street, Chicago, IL 60637 (USA), Finefield, Jennifer M., Sherman, David H., Kreitman, Martin, Williams, Robert M., Life Sciences Institute and Departments of Medicinal Chemistry, Microbiology & Immunology, and Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Department of Chemistry, Colorado State University, Fort Collins, CO 80523 (USA), The University of Colorado Cancer Center, Aurora, CO 80045 (USA) http://rwindigo1.chm.colostate.edu/, Department of Ecology and Evolution, University of Chicago, 1101 East 57th Street, Chicago, IL 60637 (USA), Finefield, Jennifer M., Sherman, David H., Kreitman, Martin, and Williams, Robert M.

Department of Chemistry and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109 (USA), Department of Chemistry, The University of Iowa, Iowa City, IA 52242 (USA), Braymer, Joseph J., O'Neill, Kevin P., Rohde, Jan???uwe, Lim, Mi Hee, Department of Chemistry and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109 (USA), Department of Chemistry, The University of Iowa, Iowa City, IA 52242 (USA), Braymer, Joseph J., O'Neill, Kevin P., Rohde, Jan???uwe, and Lim, Mi Hee

Department of Medicinal Chemistry and the Life Sciences Institute, University of Michigan, 210 Washtenaw Ave, Ann Arbor, MI 48109 (USA) http://www.lsi.umich.edu/facultyresearch/labs/garneau, Department of Molecular Microbiology and Biotechnology, Faculty of Life Sciences, Tel Aviv University (Israel), School of Chemistry, Tel Aviv University, Tel Aviv 66978 (Israel), Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University (Israel), Herzog, Ido M., Green, Keith D., Berkov???zrihen, Yifat, Feldman, Mark, Vidavski, Roee R., Eldar???boock, Anat, Satchi???fainaro, Ronit, Eldar, Avigdor, Garneau???tsodikova, Sylvie, Fridman, Micha, Department of Medicinal Chemistry and the Life Sciences Institute, University of Michigan, 210 Washtenaw Ave, Ann Arbor, MI 48109 (USA) http://www.lsi.umich.edu/facultyresearch/labs/garneau, Department of Molecular Microbiology and Biotechnology, Faculty of Life Sciences, Tel Aviv University (Israel), School of Chemistry, Tel Aviv University, Tel Aviv 66978 (Israel), Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University (Israel), Herzog, Ido M., Green, Keith D., Berkov???zrihen, Yifat, Feldman, Mark, Vidavski, Roee R., Eldar???boock, Anat, Satchi???fainaro, Ronit, Eldar, Avigdor, Garneau???tsodikova, Sylvie, and Fridman, Micha

Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), Babij, Nicholas R., Wolfe, John P., Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109???1055 (USA), Babij, Nicholas R., and Wolfe, John P.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Tel.: (+1)???734???763???1519, Fax: (+1)???734???936???7628 address, Department of Biotechnology and Biosciences, Universit?? degli Studi di Milano???Bicocca, Piazza della Scienza 2, 20126, Milano (Italy), Tel: (+39)???02???64483416, Fax: (+39)???02???64483478 address, Zampella, Giuseppe, Neupane, Kosh P., De???gioia, Luca, Pecoraro, Vincent L., Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Tel.: (+1)???734???763???1519, Fax: (+1)???734???936???7628 address, Department of Biotechnology and Biosciences, Universit?? degli Studi di Milano???Bicocca, Piazza della Scienza 2, 20126, Milano (Italy), Tel: (+39)???02???64483416, Fax: (+39)???02???64483478 address, Zampella, Giuseppe, Neupane, Kosh P., De???gioia, Luca, and Pecoraro, Vincent L.

Department of Chemistry, The University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109, USA, Department of Chemistry, Northern Kentucky University, Nunn Drive, Highland Height, KY 41099, USA, Nikolelis, Dimitrios, Department of Chemistry, The University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109, USA, Department of Chemistry, Northern Kentucky University, Nunn Drive, Highland Height, KY 41099, USA, and Nikolelis, Dimitrios

Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109 (USA), Racowski, Joy M., Gary, J. Brannon, Sanford, Melanie S., Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109 (USA), Racowski, Joy M., Gary, J. Brannon, and Sanford, Melanie S.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109???1055, USA, Bell, Andrea K., H??fler, Lajos, Meyerhoff, Mark E., Department of Chemistry, University of Michigan, Ann Arbor, MI 48109???1055, USA, Bell, Andrea K., H??fler, Lajos, and Meyerhoff, Mark E.

Life Sciences Institute, University of Michigan, 210 Washtenaw Ave., Ann Arbor, MI 48109 (USA), Fax: (+1)???734???615???5521, Chemical Biology Doctoral Program, University of Michigan, 210 Washtenaw Ave., Ann Arbor, MI 48109 (USA), Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, 210 Washtenaw Ave., Ann Arbor, MI 48109 (USA), Green, Keith D., Chen, Wenjing, Garneau???tsodikova, Sylvie, Life Sciences Institute, University of Michigan, 210 Washtenaw Ave., Ann Arbor, MI 48109 (USA), Fax: (+1)???734???615???5521, Chemical Biology Doctoral Program, University of Michigan, 210 Washtenaw Ave., Ann Arbor, MI 48109 (USA), Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, 210 Washtenaw Ave., Ann Arbor, MI 48109 (USA), Green, Keith D., Chen, Wenjing, and Garneau???tsodikova, Sylvie

Department of Chemistry, University of Michigan, 930 N University, Ann Arbor, MI 48109 (USA), Fax: (+1)???734???615???3790, Gerlach, Deidra L., Lehnert, Nicolai, Department of Chemistry, University of Michigan, 930 N University, Ann Arbor, MI 48109 (USA), Fax: (+1)???734???615???3790, Gerlach, Deidra L., and Lehnert, Nicolai

Department of Chemistry and the Macromolecular Engineering Program, University of Michigan, Ann Arbor, MI 48109???1055 (USA), Bolton, Onas, Matzger, Adam J., Department of Chemistry and the Macromolecular Engineering Program, University of Michigan, Ann Arbor, MI 48109???1055 (USA), Bolton, Onas, and Matzger, Adam J.

Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109 (USA), Emmert, Marion H., Cook, Amanda K., Xie, Yushu J., Sanford, Melanie S., Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109 (USA), Emmert, Marion H., Cook, Amanda K., Xie, Yushu J., and Sanford, Melanie S.

Department of Chemistry, University of Michigan, 930 N University, Ann Arbor, MI 48109 (USA), Fax: (+1)???734???615???3790, Gerlach, Deidra L., Lehnert, Nicolai, Department of Chemistry, University of Michigan, 930 N University, Ann Arbor, MI 48109 (USA), Fax: (+1)???734???615???3790, Gerlach, Deidra L., and Lehnert, Nicolai

Department of Chemistry and Biophysics, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109, USA, National Resource for Biomedical Supercomputing, Pittsburgh Supercomputing Center, 300 South Craig Street, Pittsburgh, PA 15213, USA phone: 412???268???4960; fax: 412???268???8200, Wymore, Troy, Chen, Brian Y., Nicholas, Hugh B., Ropelewski, Alexander J., Brooks, Charles L., Department of Chemistry and Biophysics, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109, USA, National Resource for Biomedical Supercomputing, Pittsburgh Supercomputing Center, 300 South Craig Street, Pittsburgh, PA 15213, USA phone: 412???268???4960; fax: 412???268???8200, Wymore, Troy, Chen, Brian Y., Nicholas, Hugh B., Ropelewski, Alexander J., and Brooks, Charles L.

Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109 (USA), Fax: (+1) 734-647-4865, Emmert, Marion, Gary, J. Brannon, Villalobos, Janette, Sanford, Melanie, Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI 48109 (USA), Fax: (+1) 734-647-4865, Emmert, Marion, Gary, J. Brannon, Villalobos, Janette, and Sanford, Melanie

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Faculty of Nano- and Biomedical Technologies, Saratov State University, Saratov, 410012 (Russia), Faculty of Nano- and Biomedical Technologies, Saratov State University, Saratov, 410012 (Russia) ; Department of Interfaces, Max-Planck Institute of Colloids and Interfaces, Golm/Potsdam, D14476 (Germany) ; Faculty of Nano- and Biomedical Technologies, Saratov State University, Saratov, 410012 (Russia)., Faculty of Nano- and Biomedical Technologies, Saratov State University, Saratov, 410012 (Russia) ; School of Engineering & Materials Science, Queen Mary University of London, Mile End Road, London, E1 4NS (UK), Department of Physics, Queen Mary University of London, Mile End Road, London, E1 4NS (UK), Faculty of Physics, Moscow State University, Moscow, 119899 (Russia) ; Institute of Nanotechnologies for Microelectronics, Leninsky Pr. 32a, Moscow 119991 (Russia), School of Engineering & Materials Science, Queen Mary University of London, Mile End Road, London, E1 4NS (UK), Department of Interfaces, Max-Planck Institute of Colloids and Interfaces, Golm/Potsdam, D14476 (Germany), Yashchenok, Alexey M., Bratashov, Daniil N., Gorin, Dmitry A., Lomova, Maria V., Pavlov, Anton M., Sapelkin, Andrei V., Shim, Bong Sup, Khomutov, Gennady B., Kotov, Nicholas A., Sukhorukov, Gleb B., Möhwald, Helmuth, Skirtach, Andre G., Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Faculty of Nano- and Biomedical Technologies, Saratov State University, Saratov, 410012 (Russia), Faculty of Nano- and Biomedical Technologies, Saratov State University, Saratov, 410012 (Russia) ; Department of Interfaces, Max-Planck Institute of Colloids and Interfaces, Golm/Potsdam, D14476 (Germany) ; Faculty of Nano- and Biomedical Technologies, Saratov State University, Saratov, 410012 (Russia)., Faculty of Nano- and Biomedical Technologies, Saratov State University, Saratov, 410012 (Russia) ; School of Engineering & Materials Science, Queen Mary University of London, Mile End Road, London, E1 4NS (UK), Department of Physics, Queen Mary University of London, Mile End Road, London, E1 4NS (UK), Faculty of Physics, Moscow State University, Moscow, 119899 (Russia) ; Institute of Nanotechnologies for Microelectronics, Leninsky Pr. 32a, Moscow 119991 (Russia), School of Engineering & Materials Science, Queen Mary University of London, Mile End Road, London, E1 4NS (UK), Department of Interfaces, Max-Planck Institute of Colloids and Interfaces, Golm/Potsdam, D14476 (Germany), Yashchenok, Alexey M., Bratashov, Daniil N., Gorin, Dmitry A., Lomova, Maria V., Pavlov, Anton M., Sapelkin, Andrei V., Shim, Bong Sup, Khomutov, Gennady B., Kotov, Nicholas A., Sukhorukov, Gleb B., Möhwald, Helmuth, and Skirtach, Andre G.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Fax: (+1)???734-936-7628, Neupane, Kosh P., Pecoraro, Vincent L., Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 (USA), Fax: (+1)???734-936-7628, Neupane, Kosh P., and Pecoraro, Vincent L.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, Pfxoraro, Vincent L., Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, and Pfxoraro, Vincent L.

Department of Chemistry and Biophysics, University of Michigan, Ann Arbor, MI 48109 (USA), Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208 (USA), Fax: (+1)???847-491-7713, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611 (USA), Chen, Haimei, Pazicni, Samuel, Krett, Nancy, Ahn, Richard, Penner-Hahn, James, Rosen, Steven, O'Halloran, Thomas, Department of Chemistry and Biophysics, University of Michigan, Ann Arbor, MI 48109 (USA), Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208 (USA), Fax: (+1)???847-491-7713, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611 (USA), Chen, Haimei, Pazicni, Samuel, Krett, Nancy, Ahn, Richard, Penner-Hahn, James, Rosen, Steven, and O'Halloran, Thomas