The questions of the nature and usage of information and knowledge have become especially topical during the last few years due to issues such as fake news, mis- and disinformation, and culture wars, to only name a few. In this thesis, I attempt to analyse the ways in which information and knowledge are depicted as a tool of power and how they are used in the stories, with more detailed questions based on the target story. The target text is David Mitchell’s speculative fiction novel Cloud Atlas, published in 2004. The novel is composed of six independent stories, which are, still, interconnected, and form a chronological story inside Cloud Atlas, even though they can be read as individual stories. I will analyse only four out of these six stories, for the reason that they are the most relevant for this thesis, and Letters from Zedelghem and The Ghastly Ordeal of Timothy Cavendish do not especially feature the subjects I examine in this thesis. Nevertheless, I will refer to them when necessary, from the perspective of the other parts. For example, I make multiple notions of how the protagonists Robert Frobisher and Timothy Cavendish follow the same themes as the protagonists of the other four stories. The main theme of discussion in The Pacific Journal of Adam Ewing is colonialism and the colonial discourse, as mentioned in the title of chapter 2. In chapter 2.1, I will discuss the colonial discourse in general, examining the story from the perspective of historical fiction and drawing on the notions of Lynda Ng. I also point out the references to Joseph Conrad’s Heart of Darkness, and how this earlier work relates to Cloud Atlas. In chapter 2.2, I will continue the theme of colonialism from the perspective of Christian religion and biological racism, and examine how these subjects relate to the colonialist idea. Again, I will draw on Lynda Ng, Gerd Bayer, and Diletta de Cristofaro’s research on the Pacific Journal, as well as racism studies. The analysis on racism concentrates on the types of racism: the “old” biological racism predominantly featured in the story, and the “new” cultural racism, that I consider important to mention. As I will skip the chronologically second story of Letters from Zedelghem, chapter 3 will concentrate on Half-Lives: The First Luisa Rey Mystery. The focus will be on investigative journalism and journalism’s relation to truth. In chapter 3.1, I will discuss the nature of investigative journalism in Half-Lives through character study, and after this, the epistemological dominant in relation to the detective novel and the thriller, which Half-Lives represents. For the epistemological questions, I will draw on the definitions of Brian McHale’s genre studies. Chapter 3.2 will focus on how mis- and disinformation is presented in the story, and via them, propaganda and fake news that can both be considered disinformation. In this context, I will examine how the company Seaboard Power Inc. and the gossip magazine Spyglass, which Rey works for, use information and what are the power relations. These power relations also include the activists protesting against nuclear power. I will, again, skip the chronologically next story of The Ghastly Ordeal of Timothy Cavendish, and so chapter 4 concentrates on An Orison of Sonmi-451, the first story set in the future and considered science fiction. The focus will be on counter-narratives and how they are used by Sonmi against the governing body to dispel the dominant narrative she finds untruthful. Chapter 4.1 follows in the footsteps of Half-Lives in the theme of propaganda and restricted access to information. This chapter demonstrates ways in which the dominant narrative is maintained by controlling the oppressed fabricants and the pureblood citizens of Nea So Copros. I will also analyse the references made through Sonmi’s experience and what this may mean to the reading experience. In chapter 4.2, I take a closer look at the counter-narratives and versions of truth: Sonmi, the purebloods, Unanimity, and the Archivist all have their own perspectives on what is true. Here, I will define counter-narratives with the help of Klarissa Lueg, Ann Starbœk Bager, Marianne Wolff Lundholt, Sanne Frandsen, and Timothy Kuhn. The last analysis chapter 5 focuses on the chronologically last story, Sloosha’s Crossin’ an’ Ev’rythin’ After, the post-apocalyptic part of Cloud Atlas. Chapter 5.1 will discuss the nature of the apocalypse that takes place between the chronologically last two stories, and the meaning of the knowledge lost with it. I will approach this lost knowledge from the perspective of the Valleysmen who gather and seek to preserve the knowledge of the lost, pre-apocalyptic world, and the Prescients, a scientifically more developed people. The issue between what the Valleysmen think they know and what is the truth about the apocalypse is discussed as well. In this chapter, I will use the theories and notions of Diletta de Cristofaro and Marco Caracciolo. I will also comment on Caracciolo’s “negative strategy” of world disruption in post-apocalyptic fiction. In chapter 5.2, the focus will be on the anthropological dilemma of Meronym’s character, where she has to decide whether it is ethically right to not help the Valleysmen in grave situations due to her scientist’s code. The themes of the last chapter will take us back to the beginning of Cloud Atlas, the Pacific Journal. Here, I will draw again on Lynda Ng’s notions, and briefly those of Marco Caracciolo. After this, I will present the conclusions of this thesis.