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209 results on '"D'Alessandro, Alessandra"'

1. Endoscopy management of sleeve gastrectomy stenosis: what we learned from 202 consecutive patients

Author

D’Alessandro, Alessandra, Dumont, Jean-Loup, Dagher, Ibrahim, Zito, Francesco, Galasso, Giovanni, Tranchart, Hadrien, Cereatti, Fabrizio, Catheline, Jean-Marc, Pourcher, Guillaume, Rebibo, Lionel, Calabrese, Daniela, Msika, Simon, Rotkopf, Hugo, Tuszynski, Thierry, Pacini, Filippo, Arienzo, Roberto, D’Alessandro, Antonio, Torcivia, Adriana, Genser, Laurent, Arapis, Konstantinos, Chiche, Renaud, De Palma, Giovanni Domenico, Musella, Mario, Chevallier, Jean-Marc, and Donatelli, Gianfranco

Published
2023
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2. Endoscopic Sleeve Gastroplasty

Author

Galasso, Giovanni, D’Alessandro, Alessandra, Giardiello, Cristiano, Testoni, Pier Alberto, Section editor, Testoni, Pier Alberto, editor, Inoue, Haruhiro, editor, and Wallace, Michael B., editor

Published
2022
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12. Microvascular and Macrovascular Endothelial Cell Isolation and Purification from Lung-Derived Samples

Author

Plebani, Roberto, primary, D'Alessandro, Alessandra, additional, Lanuti, Paola, additional, Simeone, Pasquale, additional, Cinalli, Massimiliano, additional, Righi, Ilaria, additional, Palleschi, Alessandro, additional, Mucci, Matteo, additional, Marchisio, Marco, additional, Cappabianca, Francesco, additional, Camera, Marina, additional, Mucilli, Felice, additional, and Romano, Mario, additional

Published
2023
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13. Endoscopy management of sleeve gastrectomy stenosis: what we learned from 202 consecutive patients

Author

D’Alessandro, Alessandra, primary, Dumont, Jean-Loup, additional, Dagher, Ibrahim, additional, Zito, Francesco, additional, Galasso, Giovanni, additional, Tranchart, Hadrien, additional, Cereatti, Fabrizio, additional, Catheline, Jean-Marc, additional, Pourcher, Guillaume, additional, Rebibo, Lionel, additional, Calabrese, Daniela, additional, Msika, Simon, additional, Rotkopf, Hugo, additional, Tuszynski, Thierry, additional, Pacini, Filippo, additional, Arienzo, Roberto, additional, D’Alessandro, Antonio, additional, Torcivia, Adriana, additional, Genser, Laurent, additional, Arapis, Konstantinos, additional, Chiche, Renaud, additional, De Palma, Giovanni Domenico, additional, Musella, Mario, additional, Chevallier, Jean-Marc, additional, and Donatelli, Gianfranco, additional

Published
2022
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14. Endoscopic Submucosal Dissection for Subepithelial Tumor Treatment in the Upper Digestive Tract: A Western, Multicenter Study

Author

Manta, Raffaele, primary, Zito, Francesco Paolo, additional, Pugliese, Francesco, additional, Caruso, Angelo, additional, Mangiafico, Santi, additional, D’Alessandro, Alessandra, additional, Castellani, Danilo, additional, Germani, Ugo, additional, Mutignani, Massimiliano, additional, Conigliaro, Rita Luisa, additional, Bonetti, Luca Reggiani, additional, Matsuda, Takahisa, additional, De Francesco, Vincenzo, additional, Zullo, Angelo, additional, and Galloro, Giuseppe, additional

Published
2022
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17. Endoscopy management of sleeve gastrectomy stenosis: what we learned from 202 consecutive patients.

Author

D'Alessandro, Alessandra, Dumont, Jean-Loup, Dagher, Ibrahim, Zito, Francesco, Galasso, Giovanni, Tranchart, Hadrien, Cereatti, Fabrizio, Catheline, Jean-Marc, Pourcher, Guillaume, Rebibo, Lionel, Calabrese, Daniela, Msika, Simon, Rotkopf, Hugo, Tuszynski, Thierry, Pacini, Filippo, Arienzo, Roberto, D'Alessandro, Antonio, Torcivia, Adriana, Genser, Laurent, and Arapis, Konstantinos

Abstract

Gastric sleeve stenosis (GSS) is described in 1%–4% of patients. To evaluate the role of endoscopy in the management of stenosis after laparoscopic sleeve gastrectomy using a standardized approach according to the characteristic of stenosis. Retrospective, observational, single-center study on patients referred from several bariatric surgery departments to an endoscopic referral center. We enrolled 202 patients. All patients underwent endoscopy in a fluoroscopy setting, and a systematic classification of the type, site, and length of the GSS was performed. According to the characteristics of the stenosis, patients underwent pneumatic dilatation or placement of a self-expandable metal stent or a lumen-apposed metal stent. Failure of endoscopic treatment was considered an indication for redo surgery, whereas patients with partial or complete response were followed up for 2 years. In the event of a recurrence, a different endoscopic approach was used. We found inflammatory strictures in 4.5% of patients, pure narrowing in 11%, and functional stenosis in 84.5%. Stenosis was in the upper tract of the stomach in 53 patients, whereas medium and distal stenosis was detected in 138 and 11 patients, respectively, and short stenosis in 194 patients. A total of 126 patients underwent pneumatic dilatation, 8 self-expandable metal stent placement, 64 lumen-apposed metal stent positioning, and 36 combined therapy. The overall rate of endoscopy success was 69%. GSS should be considered to be a chronic disease, and the endoscopic approach seems to be the most successful treatment, with a prolonged positive outcome of 69%. Characteristics of the stenosis should guide the most suitable endoscopic approach. [ABSTRACT FROM AUTHOR]

Published
2023
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26. Miscellany Complications of ERCP

Author

Zito Francesco Paolo, Germani Ugo, Raffaele Manta, Zullo Angelo, and D’ Alessandro Alessandra

Subjects
medicine.medical_specialty, Endoscopic retrograde cholangiopancreatography, medicine.diagnostic_test, Impaction, business.industry, medicine.medical_treatment, Perforation (oil well), Stent, medicine.disease, Air embolism, Surgery, surgical procedures, operative, Pneumothorax, Cholecystitis, medicine, Pancreatitis, business
Abstract

As shown in previous chapters, pancreatitis, bleeding, and perforation represent the most common adverse events following endoscopic retrograde cholangiopancreatography ERCP. However, there is a very wide range of other ERCP-related complications which occasionally may occur, such as post-procedural infections (cholangitis and cholecystitis), pneumothorax, hepatic hematomas, air embolism, splenic injury, basket/stent impaction, and other very uncommon complications. Although rare, these adverse events may be potentially life-threatening and difficult to be promptly diagnosed since the symptomatic onset is very similar at the beginning. Moreover, there is a large body of evidence showing that the occurrence of unusual complications is not predictable, even by skilled operators, and challenging to be managed.

Published
2020

28. Role of Endoscopic Internal Drainage in Treating Gastro-Bronchial and Gastro-Colic Fistula After Sleeve Gastrectomy.

Author

D'Alessandro, Alessandra, Galasso, Giovanni, Zito, Francesco Paolo, Giardiello, Cristiano, Cereatti, Fabrizio, Arienzo, Roberto, Pacini, Filippo, Chevallier, Jean-Marc, and Donatelli, Gianfranco

Subjects
SLEEVE gastrectomy, FISTULA, SURGICAL drainage, SURGICAL emergencies, ENDOSCOPIC surgery, PROGNOSIS
Abstract

Background : Gastro-bronchial and gastro-colic fistulas (GB-GC) represent a rare, but serious complication after laparoscopic sleeve gastrectomy (LSG). The aim of this study is to evaluate the efficacy of endoscopic first-line approach with endoscopic internal drainage (EID) by inserting double pigtail stents (DPS) Methods: We retrospectively analyzed data from 40 consecutive patients referred at two tertiary centers for gastro-bronchial (N=30) and gastrocolic (N=10) fistulas following LSG. Nineteen patients previously experienced emergency surgical drainage. The mean interval between the index surgery and endoscopic fistula treatment was 265.6±521 days. Results: Healing of the fistulous tract was achieved in 19 patients (47.5%), with complete resolution at an average follow-up of 16 months. Mean time of treatment duration was 157.8±141 days with 5.0±2.9 endoscopic sessions. No major adverse events were registered. Conclusions: Despite complete fistula healing was achieved in less than 50% of our population, EID for GB/GC fistula after LSG still represents the most conservative approach with low complications rate. Previous surgical drainage seems to be a positive prognostic factor for endoscopic healing. While the longer the interval between the index surgery and endoscopic treatment, the lower was the rate of treatment success. [ABSTRACT FROM AUTHOR]

Published
2022
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30. Determination of lead in blood by square wave anodic stripping voltammetry at a carbon disk ultramicroelectrode

Author

Feldman, Benjamin J., Osterloh, John D., Hata, Bernard H., and D'Alessandro, Alessandra

Subjects
Lead in the body -- Measurement, Voltammetry -- Usage, Chemistry
Abstract

A method for blood lead ([Pb]) analysis is developed based on square wave anodic stripping voltammetry (SWASV) in an [Hg.sup.2+]-containing solution using a 10-[[micro]meter]-diameter carbon disk ultramicroelectrode. SWASV eliminates interference from [O.sub.2] in unsparged blood-derived sample solutions, and filtration of acidified samples through nitrocellulose reduces the concentration of interfering substances, increasing the size and improving the uniformity of peak currents. Blood [Pb] values obtained by SWASV are compared with blood [Pb] values determined by graphite furnace atomic absorption spectrophotometry; good accuracy and reasonable coefficients of variation in the range 10.6-20% (average of 13.5%) are found for blood [Pb] ranging from 4 to 30 [[micro]gram]/dL. Preliminary experiments using a carbon disk microarray electrode suggest future improvements in sensitivity.

Published
1994

33. Gastric schwannoma misdiagnosed as a GIST

Author

Peltrini, Roberto, primary, Greco, Paola Antonella, additional, Nasto, Riccardo Aurelio, additional, D’Alessandro, Alessandra, additional, Iacobelli, Alessandro, additional, Insabato, Luigi, additional, and Bucci, Luigi, additional

Published
2019
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34. Endoscopic Submucosal Dissection for Subepithelial Tumor Treatment in the Upper Digestive Tract: A Western, Multicenter Study

Author

Manta, Raffaele, Zito, Francesco Paolo, Pugliese, Francesco, Caruso, Angelo, Mangiafico, Santi, D’Alessandro, Alessandra, Castellani, Danilo, Germani, Ugo, Mutignani, Massimiliano, Conigliaro, Rita Luisa, Bonetti, Luca Reggiani, Matsuda, Takahisa, De Francesco, Vincenzo, Zullo, Angelo, and Galloro, Giuseppe

Abstract

Background/Aims:Endoscopic submucosal dissection (ESD) has been proposed for removal of gastrointestinal subepithelial tumors (GI-SETs), but data are still scanty. This study aimed to report a case series from a western country. Patients and Methods:Data of patients with upper GI-SETs suitable for ESD removal observed in 4 centers were retrospectively reviewed. Before endoscopic procedure, the lesion was characterized by endosonographic evaluation, histology, and CT scan. The en blocresection and the R0 resection rates were calculated, as well as incidence of complications, and the 1-year follow-up was reported. Results:Data of 84 patients with esophageal (N= 13), gastric (N= 61), and duodenal (N= 10) GI-SETs were collected. The mean diameter of lesions was 26 mm (range: 12–110 mm). There were 17 gastrointestinal stromal tumors, 12 neuroendocrine tumors, 35 leiomyomas, 18 lipomas, and 2 hamartomas. En blocand R0 resection were achieved in 83 (98.8%) and in 80 (95.2%) patients, respectively. Overall, a complication occurred in 11 (13.1%) patients, including bleeding (N= 7) and perforation (N= 4). Endoscopic approach was successful in all bleedings, but 1 patient who required radiological embolization, and in 2 perforations, while surgery was performed in the other patients. Overall, a surgical approach was eventually needed in 5 (5.9%), including 3 in whom R0 resection failed and 2 with perforation. Conclusions:Our study found that ESD may be an effective and safe alternative to surgical intervention for both benign and localized malignant GI-SETs.

Published
2021
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37. Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR-α-Dependent Inhibition of Akt/mTOR Pathway

Author

SARNELLI, GIOVANNI, Gigli, Stefano, Capoccia, Elena, IUVONE, TERESA, Cirillo, Carla, Seguella, Luisa, Nobile, Nicola, D'ALESSANDRO, ALESSANDRA, PESCE, MARCELLA, Steardo, Luca, CUOMO, ROSARIO, Esposito, Giuseppe, Sarnelli, Giovanni, Gigli, Stefano, Capoccia, Elena, Iuvone, Teresa, Cirillo, Carla, Seguella, Luisa, Nobile, Nicola, D'Alessandro, Alessandra, Pesce, Marcella, Steardo, Luca, Cuomo, Rosario, and Esposito, Giuseppe

Subjects
Vascular Endothelial Growth Factor A, Neovascularization, Pathologic, proliferation, Down-Regulation, palmitoylethanolamide (PEA), Palmitic Acids, Amides, Angiogenesi, angiogenesis, Caco-2 human adenocarcinoma cell line, Ethanolamines, Cell Line, Tumor, Colonic Neoplasms, Animals, Humans, PPAR alpha, Caco-2 Cells, pharmacology, Cell Proliferation, Signal Transduction
Abstract

Palmitoylethanolamide (PEA) is a nutraceutical compound that has been demonstrated to improve intestinal inflammation. We aimed at evaluating its antiproliferative and antiangiogenic effects in human colon adenocarcinoma Caco-2 cell line. Caco-2 cells were treated with increasing concentrations of PEA (0.001, 0.01 and 0.1 μM) in the presence of peroxisome proliferator-activated receptor-a (PPAR-α) or PPAR-γ antagonists. Cell proliferation was evaluated by performing a MTT assay. Vascular endothelial growth factor (VEGF) release was estimated by ELISA, while the expression of VEGF receptor and the activation of the Akt/mammalian target of rapamycin (mTOR) pathway were evaluated by western blot analysis. PEA caused a significant and concentration-dependent decrease of Caco-2 cell proliferation at 48 h. PEA administration significantly reduced in a concentration-dependent manner VEGF secretion and VEGF receptor expression. Inhibition of Akt phosphorylation and a downstream decrease of phospho-mTOR and of p-p70S6K were observed as compared with untreated cells. PPAR-α, but not PPAR-γ antagonist, reverted all effects of PEA. PEA is able to decrease cell proliferation and angiogenesis. The antiangiogenic effect of PEA depends on the specific inhibition of the AkT/mTOR axis, through the activation of PPAR-α pathway. If supported by in vivo models, our data pave the way to PEA co-administration to the current chemotherapeutic regimens for colon carcinoma. Copyright © 2016 John WileySons, Ltd.

Published
2016

38. High prevalence of sick building syndrome in a new air-conditioned building in Italy

Author

Abbritti, Giuseppe, Muzi, Giacomo, Accattoli, Maria Patrizia, Fiordi, Tiziana, Dell'Omo, Marco, Colangeli, Carlo, Gabrielli, Anna Rita, Fabbri, Tiziana, and D'Alessandro, Alessandra

Subjects
Sick building syndrome -- Research, Air quality management -- Evaluation, Indoor air quality -- Research, Air conditioning -- Environmental aspects, Environmental issues, Health
Abstract

This study, which was conducted in central Italy, included (a) 252 office workers employed in an air-conditioned building that had fan coil units in every room (building B) and (b) 281 subjects who worked in three naturally ventilated buildings (building A) that were operated by the same public administration. The prevalence of work-related symptoms was assessed by a questionnaire that was administered by an occupational medicine specialist. The most frequent complaints of employees in building B were dry air, strong lighting, and high temperature. Emplyees who worked in this building experienced a statistically higher prevalence of symptoms that were characteristic of the sick building syndrome. This is the first time that this syndrome has been reported in Italy. Excessive illumination, a low relative humidity, and fiberglass on floors and furniture might have contributed to the symptoms. Inadequately maintenance of the building's air-conditioning plant and the employees' lack of information regarding self-regulation of the fan coil units may also have contributed to the prevalence of symptoms., RECENTLY, the attention of researchers has been focused on indoor air pollution in nonindustrial environments; many reports of symptoms or specific diseases that occur mainly in air-conditioned and mechanically ventilated [...]

Published
1992

39. Impaired post-reflux swallow-induced peristaltic wave in severe obesity and implication in esophageal hyposensitivity

Author

ZITO, FRANCESCO PAOLO, D'ALESSANDRO, ALESSANDRA, ANDREOZZI, PAOLO, PESCE, MARCELLA, EFFICIE, ELEONORA, MAIONE, FRANCESCO, DE PALMA, GIOVANNI DOMENICO, CUOMO, ROSARIO, SARNELLI, GIOVANNI, Arnone, I, Esposito, D, MAIONE FRANCESCO, Zito, FRANCESCO PAOLO, D'Alessandro, Alessandra, Andreozzi, Paolo, Pesce, Marcella, Efficie, Eleonora, Arnone, I, Maione, Francesco, Esposito, D, DE PALMA, GIOVANNI DOMENICO, Cuomo, Rosario, and Sarnelli, Giovanni

Published
2015

40. Autoimmune comorbidities in idiopathic achalasia

Author

PESCE, MARCELLA, ZITO, FRANCESCO PAOLO, D'ALESSANDRO, ALESSANDRA, ANDREOZZI, PAOLO, MAIONE, FRANCESCO, DE PALMA, GIOVANNI DOMENICO, CUOMO, ROSARIO, SARNELLI, GIOVANNI, Arnone, Mi, MAIONE FRANCESCO, Pesce, Marcella, Zito, FRANCESCO PAOLO, D'Alessandro, Alessandra, Arnone, Mi, Andreozzi, Paolo, Maione, Francesco, DE PALMA, GIOVANNI DOMENICO, Cuomo, Rosario, and Sarnelli, Giovanni

Published
2015

41. Esophageal sensitivity and impaired post-reflux swallow-induced peristaltic wave are dependent by body mass index and acid exposition

Author

ANDREOZZI, PAOLO, D'ALESSANDRO, ALESSANDRA, ZITO, FRANCESCO PAOLO, PESCE, MARCELLA, EFFICIE, ELEONORA, MAIONE, Paologiovanni, DE PALMA, GIOVANNI DOMENICO, CUOMO, ROSARIO, SARNELLI, GIOVANNI, Arnone, I, MAIONE FRANCESCO, Andreozzi, Paolo, D'Alessandro, Alessandra, Zito, FRANCESCO PAOLO, Pesce, Marcella, Efficie, Eleonora, Maione, Paologiovanni, Arnone, I, DE PALMA, GIOVANNI DOMENICO, Cuomo, Rosario, Sarnelli, Giovanni, and Maione, Francesco

Published
2015

42. Body position may change high resolution manometry parameters and drift therapeutic choice in achalasia patients

Author

PESCE, MARCELLA, D'ALESSANDRO, ALESSANDRA, ZITO, FRANCESCO PAOLO, ANDREOZZI, PAOLO, EFFICIE, ELEONORA, MAIONE, FRANCESCO, DE PALMA, GIOVANNI DOMENICO, CUOMO, ROSARIO, SARNELLI, GIOVANNI, Esposito, D, Arnone, Mi, MAIONE FRANCESCO, Pesce, Marcella, D'Alessandro, Alessandra, Zito, FRANCESCO PAOLO, Andreozzi, Paolo, Efficie, Eleonora, Esposito, D, Maione, Francesco, Arnone, Mi, DE PALMA, GIOVANNI DOMENICO, Cuomo, Rosario, and Sarnelli, Giovanni

Published
2015

43. A randomized, open-label, comparative, crossover trial on preference, efficacy, and safety profiles of lispro insulin u-100 versus concentrated lispro insulin u-200 in patients with type 2 diabetes mellitus: a possible contribution to greater treatment adherence

Author

Gentile, Sandro, primary, Fusco, Alessandra, additional, Colarusso, Sara, additional, Piscopo, Marco, additional, Improta, Maria Rosaria, additional, Corigliano, Marco, additional, Martedi, Emilia, additional, Oliva, Domenica, additional, Santorelli, Antonietta, additional, Simonetti, Rosa, additional, Giammarco, Armando, additional, Colella, Caterina, additional, Miretto, Luigia, additional, D’Alessandro, Alessandra, additional, Russo, Viviana, additional, Guarino, Giuseppina, additional, Marino, Giampiero, additional, Corigliano, Gerardo, additional, and Strollo, Felice, additional

Published
2018
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46. EARLY CHANGES IN HRM-OESOPHAGEAL PARAMETERS IN PRE AND POST TREATMENT ACHALASIA PATIENTS

Author

PESCE, MARCELLA, D'ALESSANDRO, ALESSANDRA, EFFICIE, ELEONORA, SANTONICOLA, ANTONELLA, CUOMO, ROSARIO, SARNELLI, GIOVANNI, M. Della Coletta, C. Buonfantino, M. I. Arnone, G. De Carlo, Pesce, Marcella, D'Alessandro, Alessandra, M., Della Coletta, C., Buonfantino, M. I., Arnone, G., De Carlo, Efficie, Eleonora, Santonicola, Antonella, Cuomo, Rosario, and Sarnelli, Giovanni

Published
2014

48. HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system

Author

Esposito, Giuseppe, primary, Capoccia, Elena, additional, Gigli, Stefano, additional, Pesce, Marcella, additional, Bruzzese, Eugenia, additional, D’Alessandro, Alessandra, additional, Cirillo, Carla, additional, di Cerbo, Alessandro, additional, Cuomo, Rosario, additional, Seguella, Luisa, additional, Steardo, Luca, additional, and Sarnelli, Giovanni, additional

Published
2017
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49. Allele‐specific transcriptional activity of the variable number of tandem repeats of the inducible nitric oxide synthase gene is associated with idiopathic achalasia

Author

Sarnelli, Giovanni, primary, Grosso, Michela, additional, Palumbo, Ilaria, additional, Pesce, Marcella, additional, D’Alessandro, Alessandra, additional, Zaninotto, Giovanni, additional, Annese, Vito, additional, Petruzzelli, Raffaella, additional, Izzo, Paola, additional, Sepulveres, Rossana, additional, Bruzzese, Dario, additional, Esposito, Giuseppe, additional, and Cuomo, Rosario, additional

Published
2017
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50. A new methodological approach: The combined use of two-stage streaker samplers and optical particle counters for the characterization of airborne particulate matter

Author

Mazzei, F., D'Alessandro, Alessandra, Lucarelli, F., Nava, S., Prati, Paolo, Valli, G., and Vecchi, R.

Subjects
Atmospheric Science, POSITIVE MATRIX FACTORIZATION, SOURCE APPORTIONMENT, SIZE DISTRIBUTIONS, PIXE ANALYSIS, LUNG-CANCER, AEROSOL, MASS, IMPACTOR, CALIBRATION, MODELS, Particle number, Air pollution, Mineralogy, Sampling (statistics), Particulates, medicine.disease_cause, Aerosol, medicine, Environmental science, Particle, Stage (hydrology), Particle counter, General Environmental Science
Abstract

We describe a new experimental methodology based on the contemporary use of two-stage continuous streaker samplers and optical particle counters. This is a complementary approach to size-segregated particulate matter (PM) sampling, and it is able to give information on the elemental size distribution and to assess the contribution of major PM source to size bins. PM samples in the fine and coarse fraction of PM10 have been collected by a two-stage streaker sampler and analyzed by particle-induced X-ray emission (PIXE) to obtain elemental concentration time series with hourly resolution. PM sources and profiles were singled out by positive matrix factorization (PMF). A multi-linear regression of size-segregated number of particles versus the sources, resolved by PMF, made possible the apportionment of size-segregated particles number in a fast and direct way. Results obtained in three sampling sites, located in different urban districts are discussed.

Published
2007

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