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1. Cyproheptadine resembles clozapine in vivo following both acute and chronic administration in rats

Author

Goudie, Andrew J., Cooper, Gillian D., Cole, Jon C., and Sumnall, Harry R.

Subjects
Cyproheptadine -- Dosage and administration -- Comparative analysis, Clozapine -- Dosage and administration -- Comparative analysis, Pharmaceuticals and cosmetics industries, Psychology and mental health, Comparative analysis, Dosage and administration
Abstract

Abstract Cyproheptadine is a cheap, widely available anti-allergy drug with a broad receptor binding profile which resembles that of clozapine. In rats discriminating clozapine from vehicle cyproheptadine mimicked clozapine very [...]

Published
2007

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