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Cyproheptadine resembles clozapine in vivo following both acute and chronic administration in rats

Authors :
Goudie, Andrew J.
Cooper, Gillian D.
Cole, Jon C.
Sumnall, Harry R.
Source :
Journal of Psychopharmacology. March 2007, Vol. 21 Issue 2, p179, 12 p.
Publication Year :
2007

Abstract

Abstract Cyproheptadine is a cheap, widely available anti-allergy drug with a broad receptor binding profile which resembles that of clozapine. In rats discriminating clozapine from vehicle cyproheptadine mimicked clozapine very [...]

Details

Language :
English
ISSN :
02698811
Volume :
21
Issue :
2
Database :
Gale General OneFile
Journal :
Journal of Psychopharmacology
Publication Type :
Academic Journal
Accession number :
edsgcl.160016947