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2. Outcomes Following Transcatheter Mitral Valve Replacement Using Dedicated Devices in Patients With Mitral Annular Calcification

Author

Coisne, Augustin, Ludwig, Sebastian, Scotti, Andrea, Ben Ali, Walid, Weimann, Jessica, Duncan, Alison, Webb, John G., Kalbacher, Daniel, Rudolph, Tanja K., Nickenig, Georg, Hausleiter, Jörg, Ruge, Hendrik, Adam, Matti, Petronio, Anna S., Dumonteil, Nicolas, Søndergaard, Lars, Adamo, Marianna, Regazzoli, Damiano, Garatti, Andrea, Schmidt, Tobias, Dahle, Gry, Taramasso, Maurizio, Walther, Thomas, Kempfert, Joerg, Obadia, Jean-François, Redwood, Simon, Tang, Gilbert H.L., Goel, Sachin, Fam, Neil, Metra, Marco, Andreas, Martin, Muller, David W., Denti, Paolo, Praz, Fabien, von Bardeleben, Ralph Stephan, Leroux, Lionel, Latib, Azeem, Granada, Juan F., Conradi, Lenard, and Modine, Thomas

Published
2024
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3. Transjugular Transcatheter Tricuspid Valve Replacement: Early Compassionate Use Outcomes

Author

Stolz, Lukas, Cheung, Anson, Boone, Robert, Fam, Neil, Ong, Geraldine, Villablanca, Pedro, Jabri, Ahmad, De Backer, Ole, Mølller, Jacob Eifer, Tchétché, Didier, Oliva, Omar, Chak-yu So, Kent, Lam, Yat-yin, Latib, Azeem, Scotti, Andrea, Coisne, Augustin, Sudre, Arnaud, Dreyfus, Julien, Nejjari, Mohammed, Favre, Paul-Emile, Cruz-Gonzalez, Ignacio, Estévez-Loureiro, Rodrigo, Barreiro-Perez, Manuel, Makkar, Raj, Patel, Dhairya, Leurent, Guillaume, Donal, Erwan, Modine, Thomas, and Hausleiter, Jörg

Published
2024
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5. Prognostic Implications of Residual Tricuspid Regurgitation Grading After Transcatheter Tricuspid Valve Repair

Author

Ajmone-Marsan, Nina, Alessandrini, Hannes, Badano, Luigi, Bartko, Philipp, Bax, Jeroen, Bazire, Baptiste, Benfari, Giovanni, Bernick, Jordan, Bohbot, Yohan, Carnero-Alcazar, Manuel, Chan, Vincent, Coisne, Augustin, Crestanello, Juan, De Bonis, Michele, Doguet, Fabien, Donal, Erwan, Dreyfus, Julien, Eggenspieler, Florian, Enriquez-Sarano, Maurice, Eixerés-Esteve, Andrea, Loureiro, Rodrigo Estevez, Eyharts, Damien, Fam, Neil, Flagiello, Michele, Galloo, Xavier, Gavazzoni, Mara, Habib, Gilbert, Hahn, Rebecca, Hausleiter, Jörg, Heitzinger, Gregor, Himbert, Dominique, Iliadis, Christos, Iung, Bernard, Juarez-Casso, Fernando, Kresoja, Karl-Patrick, Latib, Azeem, Lauten, Alexander, Lavie-Badie, Yoan, Le Tourneau, Thierry, Lim, Pascal, Lubos, Edith, Lurz, Philipp, Maisano, Francesco, Mbaki, Yannick, Michelena, Hector, Modine, Thomas, Messika-Zeitoun, David, Muraru, Denisa, Nejjari, Mohammed, Nickenig, Georg, Nicol, Martin, Nombela-Franco, Luis, Obadia, Jean-François, Omran, Hazem, Pedrazzini, Giovanni, Pfister, Roman, Piayda, Kerstin, Praz, Fabien, Radu, Costin, El Idrissi, Kenza Rahmouni, Riant, Elisabeth, Rodés-Cabau, Josep, Rudolph, Volker, Ruf, Tobias, Russo, Giulio, Sala, Alessandra, Schofer, Joachim, Selton-Suty, Christine, Senage, Thomas, Sievert, Horst, Stolz, Lukas, Tang, Gilbert H.L., Taramasso, Maurizio, Tomasi, Jacques, Topilsky, Yan, Tribouilloy, Christophe, Viau, Florence, von Bardeleben, Ralph Stephan, Webb, John, Weber, Marcel, Wells, George A., Windecker, Stephan, Zamorano, Jose Luis, Kresoja, Karl-Patrik, and Estevez Loureiro, Rodrigo

Published
2024
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6. Management and outcomes of pregnant women with cardiovascular diseases in a cardio-obstetric team

Author

Richardson, Marjorie, Bonnet, Jean Philippe, Coulon, Capucine, Domanski, Olivia, Constans, Benjamin, Estevez, Max Gonzalez, Gautier, Sophie, Marsili, Luisa, Hamoud, Yasmine Ould, Coisne, Augustin, Ridon, Hélène, Polge, Anne-Sophie, Mouton, Stéphanie, Haddad, Yasmine, Juthier, Francis, Moussa, Mouhamed, Vehier, Claire Mounier, Lemesle, Gilles, Schurtz, Guillaume, Garabedian, Charles, Jourdain, Mercedes, Ninni, Sandro, Brigadeau, François, Montaigne, David, Lamblin, Nicolas, and Ghesquiere, Louise

Published
2024
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7. Outcomes After Transcatheter Mitral Valve Replacement According to Regurgitation Etiology

Author

Perrin, Nils, Ben-Ali, Walid, Ludwig, Sebastian, Duncan, Alison, Weimann, Jessica, Nickenig, Georg, Tanaka, Tetsu, Coisne, Augustin, Vincentelli, Andre, Makkar, Raj, Webb, John G., Akodad, Mariama, Muller, David W.M., Jansz, Paul, Praz, Fabien, Reineke, David, Wild, Mirjam G., Hausleiter, Jörg, Goel, Sachin S., Denti, Paolo, Chehab, Omar, Dahle, Gry, Baldus, Stephan, Ruge, Hendrik, Kaneko, Tsuyoshi, Ternacle, Julien, Dumonteil, Nicolas, von Bardeleben, Ralph Stephan, Flagiello, Michele, Walther, Thomas, Taramasso, Maurizio, Søndergaard, Lars, Bleiziffer, Sabine, Fam, Neil, Kempfert, Joerg, Granada, Juan F., Tang, Gilbert H.L., Conradi, Lenard, and Modine, Thomas

Published
2024
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8. Transapical Mitral Valve Replacement: 1-Year Results of the Real-World Tendyne European Experience Registry

Author

Hell, Michaela M., Wild, Mirjam G., Baldus, Stephan, Adam, Matti, Rudolph, Tanja, Bleiziffer, Sabine, Treede, Hendrik, Ruf, Tobias F., Petronio, Anna Sonia, Colli, Andrea, Giannini, Cristina, Modine, Thomas, Bonnet, Guillaume, Andreas, Martin, Kerbel, Tillmann, Coisne, Augustin, Vincentelli, Andre, Duncan, Alison, Quarto, Cesare, Franco, Luis Nombela, Cobiella, Javier, Praz, Fabien, Ruge, Hendrik, Krane, Markus, Conradi, Lenard, Ludwig, Sebastian, Zierer, Andreas, Kellermair, Jörg, Damian, Ilinca, Anselmi, Amedeo, Donal, Erwan, Dumonteil, Nicolas, Berthoumieu, Pierre, Nickenig, Georg, Piñón, Miguel, Estevez, Rodrígo, Barth, Sebastian, Reents, Wilko, Adamo, Marianna, Dubois, Christophe, Torracca, Lucia, Fumero, Andrea, Maisano, Francesco, Denti, Paolo, Bruxelles, Gaby Aphram, Maes, Frederic, Kreidel, Felix, Munguira, Juan Bustamante, Musumeci, Francesco, Russo, Marco, Monivas, Vanessa, Walter, Thomas, Gherli, Riccardo, Lurz, Philipp, Noack, Thilo, Hausleiter, Jörg, and von Bardeleben, Ralph Stephan

Published
2024
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16. Prognostic Value of Tricuspid Valve Gradient After Transcatheter Edge-to-Edge Repair: Insights From the TriValve Registry

Author

Coisne, Augustin, Scotti, Andrea, Taramasso, Maurizio, Granada, Juan F., Ludwig, Sebastian, Rodés-Cabau, Josep, Lurz, Philipp, Hausleiter, Jörg, Fam, Neil, Kodali, Susheel K., Pozzoli, Alberto, Alessandrini, Hannes, Biasco, Luigi, Brochet, Eric, Denti, Paolo, Estevez-Loureiro, Rodrigo, Frerker, Christian, Ho, Edwin C., Monivas, Vanessa, Nickenig, Georg, Praz, Fabien, Puri, Rishi, Sievert, Horst, Tang, Gilbert H.L., Andreas, Martin, Von Bardeleben, Ralph Stephan, Rommel, Karl-Philipp, Muntané-Carol, Guillem, Gavazzoni, Mara, Braun, Daniel, Lubos, Edith, Kalbacher, Daniel, Connelly, Kim A., Juliard, Jean-Michel, Harr, Claudia, Pedrazzini, Giovanni, Philippon, François, Schofer, Joachim, Thiele, Holger, Unterhuber, Matthias, Himbert, Dominique, Alcázar, Marina Ureña, Wild, Mirjam G., Jorde, Ulrich, Windecker, Stephan, Maisano, Francesco, Leon, Martin B., Hahn, Rebecca T., and Latib, Azeem

Published
2023
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17. Routine postdilation after 23 mm Sapien 3 Ultra implantation in the aortic position

Author

Leone, Pier Pasquale, primary, Sturla, Matteo, additional, Spring, Alexander M., additional, Echarte‐Morales, Julio, additional, Scotti, Andrea, additional, Ludwig, Sebastian, additional, Coisne, Augustin, additional, Slipczuk, Leandro, additional, Assafin, Manaf, additional, Chau, Mei, additional, Ho, Edwin C., additional, Granada, Juan F., additional, and Latib, Azeem, additional

Published
2024
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18. Transcatheter Mitral Valve Replacement Versus Medical Therapy for Secondary Mitral Regurgitation: A Propensity Score–Matched Comparison

Author

Ludwig, Sebastian, Conradi, Lenard, Cohen, David J., Coisne, Augustin, Scotti, Andrea, Abraham, William T., Ben Ali, Walid, Zhou, Zhipeng, Li, Yanru, Kar, Saibal, Duncan, Alison, Lim, D. Scott, Adamo, Marianna, Redfors, Björn, Muller, David W.M., Webb, John G., Petronio, Anna S., Ruge, Hendrik, Nickenig, Georg, Sondergaard, Lars, Adam, Matti, Regazzoli, Damiano, Garatti, Andrea, Schmidt, Tobias, Andreas, Martin, Dahle, Gry, Walther, Thomas, Kempfert, Joerg, Tang, Gilbert H.L., Redwood, Simon, Taramasso, Maurizio, Praz, Fabien, Fam, Neil, Dumonteil, Nicolas, Obadia, Jean-François, von Bardeleben, Ralph Stephan, Rudolph, Tanja K., Reardon, Michael J., Metra, Marco, Denti, Paolo, Mack, Michael J., Hausleiter, Jörg, Asch, Federico M., Latib, Azeem, Lindenfeld, JoAnn, Modine, Thomas, Stone, Gregg W., and Granada, Juan F.

Published
2023
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20. Benefit of isolated surgical valve repair or replacement for functional tricuspid regurgitation and long-term outcomes stratified by the TRI-SCORE.

Author

Dreyfus, Julien, Juarez-Casso, Fernando, Sala, Alessandra, Carnero-Alcazar, Manuel, Eixerés-Esteve, Andrea, Bohbot, Yohann, Bazire, Baptiste, Flagiello, Michele, Riant, Elisabeth, Mbaki, Yannick, Tomasi, Jacques, Senage, Thomas, Idrissi, Kenza Rahmouni El, Coisne, Augustin, Eyharts, Damien, Doguet, Fabien, Viau, Florence, Eggenspieler, Florian, Heuts, Samuel, and Nia, Peyman Sardari

Subjects
TRICUSPID valve insufficiency, PATIENT selection, RANDOMIZED controlled trials, SURVIVAL rate, TRICUSPID valve surgery, DEATH rate
Abstract

Background and Aims Severe tricuspid regurgitation is associated with increased mortality rates, but benefit of its correction and ideal timing are not clearly determined. This study aimed to identify patient subsets who might benefit from the surgery. Methods In TRIGISTRY, an international cohort study of consecutive patients with severe isolated functional tricuspid regurgitation (33 centres, 10 countries), survival rates up to 10 years were compared between patients who underwent isolated tricuspid valve surgery (repair or replacement) and those conservatively managed, overall and according to TRI-SCORE category (low: ≤3, intermediate: 4–5, and high: ≥6). Results One thousand and two hundred seventeen were managed conservatively, and 551 underwent isolated tricuspid valve surgery (200 repairs and 351 replacements). TRI-SCORE distribution was 33% low, 32% intermediate, and 35% high. At 10 years, survival rates were similar between surgical and conservative management [41% vs. 36%; hazard ratio (HR).97; 95% confidence interval (CI).88–1.08, P =.57]. Surgery improved survival compared with conservative management in the low TRI-SCORE category (72% vs. 44%; HR.27; 95% CI.20–.37, P <.0001), but not in the intermediate (36% vs. 37%; HR 1.17; 95%CI.98–1.40, P =.09) or high categories (20% vs. 24%; HR 1.06; 95% CI.91–1.25, P =.45). Both repair and replacement improved survival in the low TRI-SCORE category (84% and 61% vs. 44%; HR.11; 95% CI.06–.19, P <.0001, and HR.65; 95% CI.47–.90, P =.009). Repair showed benefit in the intermediate category (59% vs. 37%; HR.49; 95% CI.35–.68, P <.0001) while replacement was possibly harmful (25% vs. 37%; HR 1.43; 95% CI 1.18–1.72, P =.0002). Conclusions Higher survival rates were observed with repair than replacement and benefit of intervention declined as TRI-SCORE increased with no benefit of any type of surgery in the high TRI-SCORE category. These results emphasize the importance of timely intervention and patient selection to achieve the best outcomes and the need for randomized controlled trials. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Initial Experience with the 4D Mini-TEE Probe in the Adult Population.

Author

Papadopoulos, Konstantinos, Ikonomidis, Ignatios, Coisne, Augustin, Özden Kayhan, Özge, Tzikas, Apostolos, Fragakis, Nikolaos, Antoniadis, Antonios P., Vannan, Mani A, and Donal, Erwan

Subjects
GENERAL anesthesia, LOCAL anesthesia, ECHOCARDIOGRAPHY, PATIENT safety, MEDICAL centers
Abstract

Background: Transesophageal echocardiography (TEE) is a vital diagnostic tool in clinical practice, particularly in transcatheter interventions where it aids in both pre-operative planning and intra-operative guidance. Traditional TEE probes often require general anesthesia due to patient discomfort. However, the development of miniaturized TEE probes presents a promising alternative, enabling routine examinations and interventions with minimal sedation. This study evaluates the feasibility of performing a complete 2D/4D TEE protocol with the new 4D mini-TEE probe in the echocardiography department and its application in transcatheter interventions. Methods: This is a retrospective study that included 30 consecutive patients from two high-volume European hospitals (Interbalkan Medical Center, Thessaloniki, Greece, and Rennes University, France) that underwent TEE or transcatheter interventions. The new 4D mini-TEE 9VT-D probe (GE Healthcare) was utilized. The quality of the images and the tolerance of the probe were assessed in the cath lab during interventions and in the echocardiography department during routine TEE examinations. Results: Direct comparison of the 4D mini-TEE probe with the standard 6VT-D probe confirmed the excellent image quality of this new pediatric probe. Most of the patients required minimal sedation or local oropharyngeal anesthesia, with satisfactory tolerance reported. Most of the transcatheter procedures did not require general anesthesia and intubation, resulting in shorter procedural time. Both 2D and 4D imaging modalities offered adequate intra-operative guidance for transcatheter procedures. Conclusions: The 4D mini-TEE probe delivers exceptional imaging capabilities for routine examinations and transcatheter interventions without needing sedation. Its use reduces esophageal trauma and the need for general anesthesia, enhancing patient comfort and safety. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Randomised study for the Optimal Treatment of symptomatic patients with low-gradient severe Aortic valve Stenosis and preserved left ventricular ejection fraction (ROTAS trial).

Author

Galli, Elena, Le Ven, Florent, Coisne, Augustin, Sportouch, Catherine, Le Tourneau, Thierry, Lavie-Badie, Yoan, Bernard, Anne, Eicher, Jean-Christophe, Dreyfus, Julien, Ternacle, Julien, Baleynaud, Serge, Auffret, Vincent, Le Pabic, Estelle, Pibarot, Philippe, Oger, Emmanuel, and Donal, Erwan

Subjects
GLOBAL longitudinal strain, VENTRICULAR ejection fraction, HEART valve prosthesis implantation, AORTIC valve diseases, COVID-19 pandemic, AORTIC stenosis, HEART failure
Published
2024
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23. Clonal Hematopoiesis Is Associated With Long-Term Adverse Outcomes Following Cardiac Surgery.

Author

Ninni, Sandro, Vicario, Rocio, Coisne, Augustin, Woitrain, Eloise, Tazibet, Amine, Stewart, Caitlin M., Diaz Jr, Luis A., White, James Robert, Koussa, Mohammed, Dubrulle, Henri, Juthier, Francis, Jungling, Marie, Vincentelli, André, Edme, Jean-Louis, Nattel, Stanley, de Winther, Menno, Geissmann, Frederic, Dombrowicz, David, Staels, Bart, and Montaigne, David

Published
2024
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24. Transcatheter Aortic Valve Replacement in Patients With Reduced Ejection Fraction and Nonsevere Aortic Stenosis

Author

Ludwig, Sebastian, Schofer, Niklas, Abdel-Wahab, Mohamed, Urena, Marina, Jean, Guillaume, Renker, Matthias, Hamm, Christian W., Thiele, Holger, Iung, Bernard, Ooms, Joris F., Wiessman, Maya, Mogensen, Nils S.B., Longère, Benjamin, Perrin, Nils, Ben Ali, Walid, Coisne, Augustin, Dahl, Jordi S., Van Mieghem, Nicolas M., Kornowski, Ran, Kim, Won-Keun, and Clavel, Marie-Annick

Published
2023
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28. TRI-SCORE and benefit of intervention in patients with severe tricuspid regurgitation

Author

Dreyfus, J, Galloo, X, Taramasso, M, Heitzinger, G, Benfari, G, Kresoja, K, Juarez-Casso, F, Omran, H, Bohbot, Y, Iliadis, C, Russo, G, Topilsky, Y, Weber, M, Nombela-Franco, L, Sala, A, Eixerés-Esteve, A, Iung, B, Obadia, J, Estevez Loureiro, R, Riant, E, Donal, E, Hausleiter, J, Badano, L, Le Tourneau, T, Coisne, A, Modine, T, Latib, A, Praz, F, Windecker, S, Zamorano, J, von Bardeleben, R, Tang, G, Hahn, R, Webb, J, Muraru, D, Nejjari, M, Chan, V, De Bonis, M, Carnero-Alcazar, M, Nickenig, G, Pfister, R, Tribouilloy, C, Rudolph, V, Crestanello, J, Lurz, P, Bartko, P, Maisano, F, Bax, J, Enriquez-Sarano, M, Messika-Zeitoun, D, Dreyfus, Julien, Galloo, Xavier, Taramasso, Maurizio, Heitzinger, Gregor, Benfari, Giovanni, Kresoja, Karl-Patrick, Juarez-Casso, Fernando, Omran, Hazem, Bohbot, Yohann, Iliadis, Christos, Russo, Giulio, Topilsky, Yan, Weber, Marcel, Nombela-Franco, Luis, Sala, Alessandra, Eixerés-Esteve, Andrea, Iung, Bernard, Obadia, Jean-François, Estevez Loureiro, Rodrigo, Riant, Elisabeth, Donal, Erwan, Hausleiter, Jörg, Badano, Luigi, Le Tourneau, Thierry, Coisne, Augustin, Modine, Thomas, Latib, Azeem, Praz, Fabien, Windecker, Stephan, Zamorano, Jose Luis, von Bardeleben, Ralph Stephan, Tang, Gilbert H L, Hahn, Rebecca, Webb, John, Muraru, Denisa, Nejjari, Mohammed, Chan, Vincent, De Bonis, Michele, Carnero-Alcazar, Manuel, Nickenig, Georg, Pfister, Roman, Tribouilloy, Christophe, Rudolph, Volker, Crestanello, Juan, Lurz, Philipp, Bartko, Philipp, Maisano, Francesco, Bax, Jeroen, Enriquez-Sarano, Maurice, Messika-Zeitoun, David, Dreyfus, J, Galloo, X, Taramasso, M, Heitzinger, G, Benfari, G, Kresoja, K, Juarez-Casso, F, Omran, H, Bohbot, Y, Iliadis, C, Russo, G, Topilsky, Y, Weber, M, Nombela-Franco, L, Sala, A, Eixerés-Esteve, A, Iung, B, Obadia, J, Estevez Loureiro, R, Riant, E, Donal, E, Hausleiter, J, Badano, L, Le Tourneau, T, Coisne, A, Modine, T, Latib, A, Praz, F, Windecker, S, Zamorano, J, von Bardeleben, R, Tang, G, Hahn, R, Webb, J, Muraru, D, Nejjari, M, Chan, V, De Bonis, M, Carnero-Alcazar, M, Nickenig, G, Pfister, R, Tribouilloy, C, Rudolph, V, Crestanello, J, Lurz, P, Bartko, P, Maisano, F, Bax, J, Enriquez-Sarano, M, Messika-Zeitoun, D, Dreyfus, Julien, Galloo, Xavier, Taramasso, Maurizio, Heitzinger, Gregor, Benfari, Giovanni, Kresoja, Karl-Patrick, Juarez-Casso, Fernando, Omran, Hazem, Bohbot, Yohann, Iliadis, Christos, Russo, Giulio, Topilsky, Yan, Weber, Marcel, Nombela-Franco, Luis, Sala, Alessandra, Eixerés-Esteve, Andrea, Iung, Bernard, Obadia, Jean-François, Estevez Loureiro, Rodrigo, Riant, Elisabeth, Donal, Erwan, Hausleiter, Jörg, Badano, Luigi, Le Tourneau, Thierry, Coisne, Augustin, Modine, Thomas, Latib, Azeem, Praz, Fabien, Windecker, Stephan, Zamorano, Jose Luis, von Bardeleben, Ralph Stephan, Tang, Gilbert H L, Hahn, Rebecca, Webb, John, Muraru, Denisa, Nejjari, Mohammed, Chan, Vincent, De Bonis, Michele, Carnero-Alcazar, Manuel, Nickenig, Georg, Pfister, Roman, Tribouilloy, Christophe, Rudolph, Volker, Crestanello, Juan, Lurz, Philipp, Bartko, Philipp, Maisano, Francesco, Bax, Jeroen, Enriquez-Sarano, Maurice, and Messika-Zeitoun, David

Abstract

BACKGROUND AND AIMS: Benefit of tricuspid regurgitation (TR) correction and timing of intervention are unclear. This study aimed to compare survival rates after surgical or transcatheter intervention to conservative management according to a TR clinical stage as assessed using the TRI-SCORE. METHODS: A total of 2,413 patients with severe isolated functional TR were enrolled in TRIGISTRY (1217 conservatively managed, 551 isolated tricuspid valve surgery, and 645 transcatheter valve repair). The primary endpoint was survival at 2 years. RESULTS: The TRI-SCORE was low (≤3) in 32%, intermediate (4-5) in 33%, and high (≥6) in 35%. A successful correction was achieved in 97% and 65% of patients in the surgical and transcatheter groups, respectively. Survival rates decreased with the TRI-SCORE in the three treatment groups (all P < .0001). In the low TRI-SCORE category, survival rates were higher in the surgical and transcatheter groups than in the conservative management group (93%, 87%, and 79%, respectively, P = .0002). In the intermediate category, no significant difference between groups was observed overall (80%, 71%, and 71%, respectively, P = .13) but benefit of the intervention became significant when the analysis was restricted to patients with successful correction (80%, 81%, and 71%, respectively, P = .009). In the high TRI-SCORE category, survival was not different to conservative management in the surgical and successful repair group (61% and 68% vs 58%, P = .26 and P = .18 respectively). CONCLUSIONS: Survival progressively decreased with the TRI-SCORE irrespective of treatment modality. Compared to conservative management, an early and successful surgical or transcatheter intervention improved 2-year survival in patients at low and, to a lower extent, intermediate TRI-SCORE, while no benefit was observed in the high TRI-SCORE category.

Published
2024

30. Reproducibility of reading echocardiographic parameters to assess severity of mitral regurgitation. Insights from a French multicentre study

Author

Coisne, Augustin, Aghezzaf, Samy, Edmé, Jean-Louis, Bernard, Anne, Ma, Iria, Bohbot, Yohann, Di Lena, Chloé, Nicol, Martin, Lavie Badie, Yoan, Eyharts, Damien, Seemann, Aurélien, Falaise, Claire, Ternacle, Julien, Nguyen, Annabelle, Montier, Geraldine, Hubert, Arnaud, Montaigne, David, Donal, Erwan, and Dreyfus, Julien

Published
2020
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32. Feasibility and prognostic significance of ventricular–arterial coupling after myocardial infarction: the RIGID-MI cohort

Author

Aghezzaf, Samy, primary, Coisne, Augustin, additional, Bauters, Christophe, additional, Favata, Francesco, additional, Delsart, Pascal, additional, Coppin, Amandine, additional, Seunes, Claire, additional, Schurtz, Guillaume, additional, Verdier, Basile, additional, Lamblin, Nicolas, additional, Tazibet, Amine, additional, Le Taillandier de Gabory, Justine, additional, Ninni, Sandro, additional, Donal, Erwan, additional, Lemesle, Gilles, additional, and Montaigne, David, additional

Published
2023
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33. Regurgitant Volume to LA Volume Ratio in Patients with Secondary MR: The COAPT Trial

Author

Coisne, Augustin, primary, Scotti, Andrea, additional, Granada, Juan F, additional, Grayburn, Paul A, additional, Mack, Michael J, additional, Cohen, David J, additional, Kar, Saibal, additional, Lim, D Scott, additional, Lindenfeld, JoAnn, additional, Bax, Jeroen, additional, Kotinkaduwa, Lak N, additional, Redfors, Björn, additional, Weissman, Neil J, additional, Asch, Federico M, additional, and Stone, Gregg W, additional

Published
2023
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34. Novel Multiphase Assessment for Predicting Left Ventricular Outflow Tract Obstruction Before Transcatheter Mitral Valve Replacement

Author

Meduri, Christopher U., Reardon, Michael J., Lim, D. Scott, Howard, Elliot, Dunnington, Gan, Lee, David P., Liang, David, Gooley, Robert, O’Hair, Daniel, Ng, Martin K., Walton, Antony, Spargias, Konstantinos, Blackman, Daniel, Coisne, Augustin, Hildick-Smith, David, De Gouy, Marine, Chenoweth, Sharla, Kar, Saibal, McCarthy, Patrick M., Piazza, Nicolo, Qasam, Atif, Martin, Randolph P., Leon, Martin B., Mack, Michael J., Adams, David H., and Bapat, Vinayak

Published
2019
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42. Regurgitant volume to LA volume ratio in patients with secondary MR: the COAPT trial.

Author

Coisne, Augustin, Scotti, Andrea, Granada, Juan F, Grayburn, Paul A, Mack, Michael J, Cohen, David J, Kar, Saibal, Lim, D Scott, Lindenfeld, JoAnn, Bax, Jeroen, Kotinkaduwa, Lak N, Redfors, Björn, Weissman, Neil J, Asch, Federico M, and Stone, Gregg W

Subjects
LEFT heart atrium, RESEARCH funding, T-test (Statistics), FISHER exact test, DESCRIPTIVE statistics, CHI-squared test, MANN Whitney U Test, MITRAL valve insufficiency, KAPLAN-Meier estimator, LOG-rank test, CONCEPTUAL structures, DATA analysis software, CONFIDENCE intervals, PROPORTIONAL hazards models
Abstract

Aims The conceptual framework of proportionate vs. disproportionate mitral regurgitation (MR) translates poorly to individual patients with heart failure (HF) and secondary MR. A novel index, the ratio of MR severity to left atrial volume (LAV), may identify patients with 'disproportionate' MR and a higher risk of events. The objectives, therefore, were to investigate the prognostic impact of MR severity to LAV ratio on outcomes among HF patients with severe secondary MR randomized to transcatheter edge-to-edge repair (TEER) with the MitraClip™ device plus guideline-directed medical therapy (GDMT) vs. GDMT alone in the COAPT trial. Methods and results The ratio of pre-procedural regurgitant volume (RVol) to LAV was calculated from baseline transthoracic echocardiograms. The primary endpoint was 2-year covariate-adjusted rate of HF hospitalization (HFH). Among 567 patients, the median RVol/LAV was 0.67 (interquartile range 0.48–0.91). In patients randomized to GDMT alone, lower RVol/LAV was independently associated with an increased 2-year risk of HFH (adjHR: 1.77; 95% CI: 1.20–2.63). RVol/LAV was a stronger predictor of adverse outcomes than RVol or LAV alone. Treatment with TEER plus GDMT compared with GDMT alone was associated with lower 2-year rates of HFH both in patients with low and high RVol/LAV (P interaction = 0.28). Baseline RVol/LAV ratio was unrelated to 2-year mortality, health status, or functional capacity in either treatment group. Conclusion Low RVol/LAV ratio was an independent predictor of 2-year HFH in HF patients with severe MR treated with GDMT alone in the COAPT trial. TEER improved outcomes regardless of baseline RVol/LAV ratio. Clinical Trial Registration Trial Name: Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) (COAPT) ClinicalTrial.gov Identifier NCT01626079 URL https://clinicaltrials.gov/ct2/show/NCT01626079 [ABSTRACT FROM AUTHOR]

Published
2024
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43. Feasibility and prognostic significance of ventricular–arterial coupling after myocardial infarction: the RIGID-MI cohort.

Author

Aghezzaf, Samy, Coisne, Augustin, Bauters, Christophe, Favata, Francesco, Delsart, Pascal, Coppin, Amandine, Seunes, Claire, Schurtz, Guillaume, Verdier, Basile, Lamblin, Nicolas, Tazibet, Amine, Gabory, Justine Le Taillandier de, Ninni, Sandro, Donal, Erwan, Lemesle, Gilles, and Montaigne, David

Subjects
MYOCARDIAL infarction, VENTRICULAR ejection fraction, RECEIVER operating characteristic curves, RESEARCH funding, MAJOR adverse cardiovascular events, ISOMETRIC exercise, PERIPHERAL vascular diseases, CARDIOVASCULAR system physiology, PULSE wave analysis, CONFIDENCE intervals, ECHOCARDIOGRAPHY, GRIP strength
Abstract

Aims The clinical significance and feasibility of the recently described non-invasive parameters exploring ventricular–arterial coupling (VAC) remain uncertain. This study aimed to assess VAC parameters for prognostic stratification in stable patients with left ventricular ejection fraction (LVEF) ≥40% following myocardial infarction (MI). Methods and results Between 2018 and 2021, patients with LVEF ≥40% were evaluated 1 month following MI using transthoracic echocardiography (TTE) and arterial tonometry at rest and after a handgrip test. VAC was studied via the ratio between arterial elastance (Ea) and end-systolic LV elastance (Ees) and between pulse wave velocity (PWV) and global longitudinal strain (GLS). Patients were followed for major adverse cardiovascular events (MACE): all-cause death, acute heart failure, stroke, AMI, and urgent cardiovascular hospitalization. Among the 374 patients included, Ea/Ees and PWV/GLS were obtained at rest for 354 (95%) and 253 patients (68%), respectively. Isometric exercise was workable in 335 patients (85%). During a median follow-up of 32 months (interquartile range: 16–42), 41 (11%) MACE occurred. Patients presenting MACE were significantly older and had a higher prevalence of peripheral arterial disease, lower GLS, higher Ea, PWV, and PWV/GLS ratio. The Ea/Ees ratio and standard TTE parameters during isometric exercise were not associated with MACE. After adjustment, the PWV/GLS ratio was the only VAC parameter independently associated with outcome. Receiver operating characteristic curve analysis identified a PWV/GLS ratio >0.70 (Youden's index = 0.37) as the best threshold to identify patients developing MACE: hazard ratio (95% confidence interval) = 2.2 (1.14–4.27), P = 0.02. Conclusion The PWV/GLS ratio, assessed 1 month after MI, identifies a group of patients at higher risk of MACE providing additional value on top of conventional non-invasive parameters. [ABSTRACT FROM AUTHOR]

Published
2024
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46. Outcomes After Transcatheter Mitral Valve Replacement According to Regurgitation Etiology

Author

Perrin, Nils, primary, Ben Ali, Walid, additional, Ludwig, Sebastian, additional, Duncan, Alison, additional, Weimann, Jessica, additional, Nickenig, Georg, additional, Tanaka, Tetsu, additional, Coisne, Augustin, additional, Vincentelli, Andre, additional, Makkar, Raj, additional, Webb, John G., additional, Akodad, Mariama, additional, Muller, David W.M., additional, Jansz, Paul, additional, Praz, Fabien, additional, Reineke, David, additional, Wild, Mirjam G., additional, Hausleiter, Jörg, additional, Goel, Sachin S., additional, Denti, Paolo, additional, Chehab, Omar, additional, Dahle, Gry, additional, Baldus, Stephan, additional, Ruge, Hendrik, additional, Kaneko, Tsuyoshi, additional, Ternacle, Julien, additional, Dumonteil, Nicolas, additional, Stephan von Bardeleben, Ralph, additional, Flagiello, Michele, additional, Walther, Thomas, additional, Taramasso, Maurizio, additional, Søndergaard, Lars, additional, Bleiziffer, Sabine, additional, Fam, Neil, additional, Kempfert, Joerg, additional, Granada, Juan F., additional, Tang, Gilbert H.L., additional, Conradi, Lenard, additional, and Modine, Thomas, additional

Published
2023
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47. Transcatheter mitral valve replacement or repair for secondary mitral regurgitation: a propensity score‐matched analysis

Author

Ludwig, Sebastian, Kalbacher, Daniel, Ali, Walid Ben, Weimann, Jessica, Adam, Matti, Duncan, Alison, Webb, John G, Windecker, Stephan, Orban, Mathias, Giannini, Cristina, Coisne, Augustin, Karam, Nicole, Scotti, Andrea, Sondergaard, Lars, Adamo, Marianna, Muller, David W M, Butter, Christian, Denti, Paolo, Melica, Bruno, Regazzoli, Damiano, Garatti, Andrea, Schmidt, Tobias, Andreas, Martin, Dahle, Gry, Taramasso, Maurizio, Nickenig, Georg, Dumonteil, Nicolas, Walther, Thomas, Flagiello, Michele, Kempfert, Joerg, Fam, Neil, Ruge, Hendrik, Rudolph, Tanja K, Wyler von Ballmoos, Moritz C, Metra, Marco, Redwood, Simon, Granada, Juan F, Tang, Gilbert H L, Latib, Azeem, Lurz, Philipp, von Bardeleben, Ralph Stephan, Modine, Thomas, Hausleiter, Jörg, and Conradi, Lenard

Subjects
Functional mitral regurgitation, Secondary mitral regurgitation, Transcatheter edge-to-edge repair, Transcatheter mitral valve replacement, Cardiology and Cardiovascular Medicine
Published
2023

48. Arterial Pulsatility and Circulating von Willebrand Factor in Patients on Mechanical Circulatory Support

Author

Vincent, Flavien, Rauch, Antoine, Loobuyck, Valentin, Robin, Emmanuel, Nix, Christoph, Vincentelli, André, Smadja, David M., Leprince, Pascal, Amour, Julien, Lemesle, Gilles, Spillemaeker, Hugues, Debry, Nicolas, Latremouille, Christian, Jansen, Piet, Capel, Antoine, Moussa, Mouhamed, Rousse, Natacha, Schurtz, Guillaume, Delhaye, Cédric, Paris, Camille, Jeanpierre, Emmanuelle, Dupont, Annabelle, Corseaux, Delphine, Rosa, Mickaël, Sottejeau, Yoann, Barth, Svenja, Mourran, Claudia, Gomane, Valérie, Coisne, Augustin, Richardson, Marjorie, Caron, Claudine, Preda, Cristian, Ung, Alexandre, Carpentier, Alain, Hubert, Thomas, Denis, Cécile, Staels, Bart, Lenting, Peter J., Van Belle, Eric, and Susen, Sophie

Published
2018
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49. Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study

Author

Montaigne, David, Marechal, Xavier, Modine, Thomas, Coisne, Augustin, Mouton, Stéphanie, Fayad, Georges, Ninni, Sandro, Klein, Cédric, Ortmans, Staniel, Seunes, Claire, Potelle, Charlotte, Berthier, Alexandre, Gheeraert, Celine, Piveteau, Catherine, Deprez, Rebecca, Eeckhoute, Jérome, Duez, Hélène, Lacroix, Dominique, Deprez, Benoit, Jegou, Bruno, Koussa, Mohamed, Edme, Jean-Louis, Lefebvre, Philippe, and Staels, Bart

Published
2018
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50. Early Experience With New Transcatheter Mitral Valve Replacement

Author

Kleiman, Neal S., Reardon, Michael, Bajwa, Tanvir, O’Hair, Daniel, Rajagopal, Vivek, Meduri, Christopher, Williams, Mathew, Jilaihawi, Hasan, Sorajja, Paul, Farivar, R. Saeid, Walton, Antony, Duffy, Stephen, Gooley, Robert, Almeida, Aubrey, Ng, Martin, Wilson, Michael, Spargias, Konstantinos, Pattakos, Stratis, Laine, Mika, Haenninen, Helena, Modine, Thomas, Coisne, Augustin, Hildick-Smith, David, Trivedi, Uday, Blackman, Daniel, Evans, Betsy, Rajani, Ronak, Redwood, Simon, Bapat, Vinayak, Duffy, Stephen J., Reardon, Michael J., Ng, Martin K., Adams, David H., Leon, Martin, Mack, Michael J., and Chenoweth, Sharla

Published
2018
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