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1. Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design

Author

Oelsner, Elizabeth C, Krishnaswamy, Akshaya, Balte, Pallavi P, Allen, Norrina Bai, Ali, Tauqeer, Anugu, Pramod, Andrews, Howard F, Arora, Komal, Asaro, Alyssa, Barr, R Graham, Bertoni, Alain G, Bon, Jessica, Boyle, Rebekah, Chang, Arunee A, Chen, Grace, Coady, Sean, Cole, Shelley A, Coresh, Josef, Cornell, Elaine, Correa, Adolfo, Couper, David, Cushman, Mary, Demmer, Ryan T, Elkind, Mitchell SV, Folsom, Aaron R, Fretts, Amanda M, Gabriel, Kelley P, Gallo, Linda C, Gutierrez, Jose, Han, Mei Lan K, Henderson, Joel M, Howard, Virginia J, Isasi, Carmen R, Jacobs, David R, Judd, Suzanne E, Mukaz, Debora Kamin, Kanaya, Alka M, Kandula, Namratha R, Kaplan, Robert C, Kinney, Gregory L, Kucharska-Newton, Anna, Lee, Joyce S, Lewis, Cora E, Levine, Deborah A, Levitan, Emily B, Levy, Bruce D, Make, Barry J, Malloy, Kimberly, Manly, Jennifer J, Mendoza-Puccini, Carolina, Meyer, Katie A, Min, Yuan-I Nancy, Moll, Matthew R, Moore, Wendy C, Mauger, David, Ortega, Victor E, Palta, Priya, Parker, Monica M, Phipatanakul, Wanda, Post, Wendy S, Postow, Lisa, Psaty, Bruce M, Regan, Elizabeth A, Ring, Kimberly, Roger, Véronique L, Rotter, Jerome I, Rundek, Tatjana, Sacco, Ralph L, Schembri, Michael, Schwartz, David A, Seshadri, Sudha, Shikany, James M, Sims, Mario, Stukovsky, Karen D Hinckley, Talavera, Gregory A, Tracy, Russell P, Umans, Jason G, Vasan, Ramachandran S, Watson, Karol E, Wenzel, Sally E, Winters, Karen, Woodruff, Prescott G, Xanthakis, Vanessa, Zhang, Ying, Zhang, Yiyi, and Investigators, for the C4R

Subjects
Public Health, Health Sciences, Social Determinants of Health, Basic Behavioral and Social Science, Coronaviruses Disparities and At-Risk Populations, Prevention, Coronaviruses, Infectious Diseases, Clinical Research, Emerging Infectious Diseases, Behavioral and Social Science, Aetiology, 2.4 Surveillance and distribution, Good Health and Well Being, Adolescent, Adult, Aged, Aged, 80 and over, COVID-19, Cohort Studies, Humans, Middle Aged, Pandemics, Prospective Studies, SARS-CoV-2, United States, Young Adult, cohort studies, coronavirus disease 2019, severe acute respiratory syndrome coronavirus 2, %22">>, C4R Investigators, severe acute respiratory syndrome coronavirus 2, Mathematical Sciences, Medical and Health Sciences, Epidemiology
Abstract

The Collaborative Cohort of Cohorts for COVID-19 Research (C4R) is a national prospective study of adults comprising 14 established US prospective cohort studies. Starting as early as 1971, investigators in the C4R cohort studies have collected data on clinical and subclinical diseases and their risk factors, including behavior, cognition, biomarkers, and social determinants of health. C4R links this pre-coronavirus disease 2019 (COVID-19) phenotyping to information on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and acute and postacute COVID-related illness. C4R is largely population-based, has an age range of 18-108 years, and reflects the racial, ethnic, socioeconomic, and geographic diversity of the United States. C4R ascertains SARS-CoV-2 infection and COVID-19 illness using standardized questionnaires, ascertainment of COVID-related hospitalizations and deaths, and a SARS-CoV-2 serosurvey conducted via dried blood spots. Master protocols leverage existing robust retention rates for telephone and in-person examinations and high-quality event surveillance. Extensive prepandemic data minimize referral, survival, and recall bias. Data are harmonized with research-quality phenotyping unmatched by clinical and survey-based studies; these data will be pooled and shared widely to expedite collaboration and scientific findings. This resource will allow evaluation of risk and resilience factors for COVID-19 severity and outcomes, including postacute sequelae, and assessment of the social and behavioral impact of the pandemic on long-term health trajectories.

Published
2022

2. Knowledge Gaps, Challenges, and Opportunities in Health and Prevention Research for Asian Americans, Native Hawaiians, and Pacific Islanders: A Report From the 2021 National Institutes of Health Workshop.

Author

Kanaya, Alka M, Hsing, Ann W, Panapasa, Sela V, Kandula, Namratha R, Araneta, Maria Rosario G, Shimbo, Daichi, Wang, Paul, Gomez, Scarlett L, Lee, Jinkook, Narayan, KM Venkat, Mau, Marjorie KL Mala, Bose, Sonali, Daviglus, Martha L, Hu, Frank B, Islam, Nadia, Jackson, Chandra L, Kataoka-Yahiro, Merle, Kauwe, John SK, Liu, Simin, Ma, Grace X, Nguyen, Tung, Palaniappan, Latha, Setiawan, V Wendy, Trinh-Shevrin, Chau, Tsoh, Janice Y, Vaidya, Dhananjay, Vickrey, Barbara, Wang, Thomas J, Wong, Nathan D, Coady, Sean, and Hong, Yuling

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Prevention, Cardiovascular, Good Health and Well Being, Asian, Hawaii, Health Promotion, Humans, National Institutes of Health (U.S.), Native Hawaiian or Other Pacific Islander, United States, Public Health and Health Services
Abstract

Asian Americans (AsA), Native Hawaiians, and Pacific Islanders (NHPI) comprise 7.7% of the U.S. population, and AsA have had the fastest growth rate since 2010. Yet the National Institutes of Health (NIH) has invested only 0.17% of its budget on AsA and NHPI research between 1992 and 2018. More than 40 ethnic subgroups are included within AsA and NHPI (with no majority subpopulation), which are highly diverse culturally, demographically, linguistically, and socioeconomically. However, data for these groups are often aggregated, masking critical health disparities and their drivers. To address these issues, in March 2021, the National Heart, Lung, and Blood Institute, in partnership with 8 other NIH institutes, convened a multidisciplinary workshop to review current research, knowledge gaps, opportunities, barriers, and approaches for prevention research for AsA and NHPI populations. The workshop covered 5 domains: 1) sociocultural, environmental, psychological health, and lifestyle dimensions; 2) metabolic disorders; 3) cardiovascular and lung diseases; 4) cancer; and 5) cognitive function and healthy aging. Two recurring themes emerged: Very limited data on the epidemiology, risk factors, and outcomes for most conditions are available, and most existing data are not disaggregated by subgroup, masking variation in risk factors, disease occurrence, and trajectories. Leveraging the vast phenotypic differences among AsA and NHPI groups was identified as a key opportunity to yield novel clues into etiologic and prognostic factors to inform prevention efforts and intervention strategies. Promising approaches for future research include developing collaborations with community partners, investing in infrastructure support for cohort studies, enhancing existing data sources to enable data disaggregation, and incorporating novel technology for objective measurement. Research on AsA and NHPI subgroups is urgently needed to eliminate disparities and promote health equity in these populations.

Published
2022

4. World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions

Author

Kaptoge, Stephen, Pennells, Lisa, De Bacquer, Dirk, Cooney, Marie Therese, Kavousi, Maryam, Stevens, Gretchen, Riley, Leanne Margaret, Savin, Stefan, Khan, Taskeen, Altay, Servet, Amouyel, Philippe, Assmann, Gerd, Bell, Steven, Ben-Shlomo, Yoav, Berkman, Lisa, Beulens, Joline W, Björkelund, Cecilia, Blaha, Michael, Blazer, Dan G, Bolton, Thomas, Bonita Beaglehole, Ruth, Brenner, Hermann, Brunner, Eric J, Casiglia, Edoardo, Chamnan, Parinya, Choi, Yeun-Hyang, Chowdry, Rajiv, Coady, Sean, Crespo, Carlos J, Cushman, Mary, Dagenais, Gilles R, D'Agostino Sr, Ralph B, Daimon, Makoto, Davidson, Karina W, Engström, Gunnar, Ford, Ian, Gallacher, John, Gansevoort, Ron T, Gaziano, Thomas Andrew, Giampaoli, Simona, Grandits, Greg, Grimsgaard, Sameline, Grobbee, Diederick E, Gudnason, Vilmundur, Guo, Qi, Tolonen, Hanna, Humphries, Steve, Iso, Hiroyasu, Jukema, J Wouter, Kauhanen, Jussi, Kengne, Andre Pascal, Khalili, Davood, Koenig, Wolfgang, Kromhout, Daan, Krumholz, Harlan, Lam, TH, Laughlin, Gail, Marín Ibañez, Alejandro, Meade, Tom W, Moons, Karel G M, Nietert, Paul J, Ninomiya, Toshiharu, Nordestgaard, Børge G, O'Donnell, Christopher, Palmieri, Luigi, Patel, Anushka, Perel, Pablo, Price, Jackie F, Providencia, Rui, Ridker, Paul M, Rodriguez, Beatriz, Rosengren, Annika, Roussel, Ronan, Sakurai, Masaru, Salomaa, Veikko, Sato, Shinichi, Schöttker, Ben, Shara, Nawar, Shaw, Jonathan E, Shin, Hee-Choon, Simons, Leon A, Sofianopoulou, Eleni, Sundström, Johan, Völzke, Henry, Wallace, Robert B, Wareham, Nicholas J, Willeit, Peter, Wood, David, Wood, Angela, Zhao, Dong, Woodward, Mark, Danaei, Goodarz, Roth, Gregory, Mendis, Shanthi, Onuma, Oyere, Varghese, Cherian, Ezzati, Majid, Graham, Ian, Jackson, Rod, Danesh, John, and Di Angelantonio, Emanuele

Published
2019
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6. 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Author

Goff, David C., Jr., Lloyd-Jones, Donald M., Bennett, Glen, Coady, Sean, D’Agostino, Ralph B., Sr., Gibbons, Raymond, Greenland, Philip, Lackland, Daniel T., Levy, Daniel, O’Donnell, Christopher J., Robinson, Jennifer G., Schwartz, J. Sanford, Shero, Susan T., Smith, Sidney C., Jr., Sorlie, Paul, Stone, Neil J., and Wilson, Peter W.F.

Published
2014
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9. Abstract 18061: Predictors of Hospitalization or Death Due to Heart Failure in Diabetic Patients by Gender in the ACCORD Trial Using Random Survival Forests

Author

Patel, Tejas, Shamsuzzaman, Md, Wu, Colin, Navarro Almario, Eileen, Tesfaldet, Bereket, Fleg, Jerome, Csako, Gyorgy, Gandotra, Charu, Sopko, George, Sviglin, Helena, Coady, Sean, Burkhart, Keith, Calis, Karim, Cooper, Lawton, Amin, Neha, Banerjee, Avantika, Farooque, Nashwan, Taylor, Austin, Gupta, Shivani, Dodge, Andrew, Dandi, Gauri, Hoque, Laboni, Fennessy, Michelle, Raman, Subha, Kirby, Ruth, Chen, Jue, Yan, Ye, Liu, Lijuan, Leifer, Eric, Chang, Henry, Cure, Carlos, Desvigne-Nickens, Patrice, Szarfman, Ana, Domanski, Michael, Pucino, Frank, Rosenberg, Yves, and Hasan, Ahmed

Published
2017

10. Abstract 18043: Identifying Predictors for All-Cause Mortality in Diabetic Patients in the ACCORD Trial Using Random Survival Forests

Author

Shamsuzzaman, Md, Patel, Tejas, Navarro Almario, Eileen, Wu, Colin, Tesfaldet, Bereket, Fleg, Jerome, Csako, Gyorgy, Gandotra, Charu, Sopko, George, Sviglin, Helena, Cooper, Lawton, Coady, Sean, Amin, Neha, Banerjee, Avantika, Farooque, Nashwan, Taylor, Austin, Dodge, Andrew, Gupta, Shivani, Dandi, Gauri, Hoque, Laboni, Fennessy, Michelle, Raman, Subha, Cure, Carlos, Kirby, Ruth, Liu, Lijuan, Chen, Jue, Yan, Ye, Burkhart, Keith, Calis, Karim, Leifer, Eric, Chang, Henry, Szarfman, Ana, Domanski, Michael, Pucino, Frank, Rosenberg, Yves, and Hasan, Ahmed

Published
2017

15. Trends in cardiovascular complications of diabetes

Author

Fox, Caroline S., Coady, Sean, Sorlie, Paul D., Levy, Daniel, Meigs, James B., D'Agostino, Ralph B., Sr., Wilson, W.F. Peter, and Savage, Peter J.

Subjects
Cardiovascular diseases -- Surveys, Cardiovascular diseases -- Diagnosis, Diabetes -- Surveys
Abstract

A study was conducted to determine whether adults with and without diabetes experienced similar declines in incident cardiovascular disease (CVD) in 1950-1995.The results reported a 50% reduction in the rate of incident CVD events among adults with diabetes, although the absolute risk of CVD is 2-fold greater than among persons without diabetes.

Published
2004

17. Funding of Hispanic/Latino Health-Related Research by the National Institutes of Health: An Analysis of the Portfolio of Research Program Grants on Six Health Topic Areas

Author

Avilés-Santa, M. Larissa, primary, Hsu, Laura, additional, Lam, Tram Kim, additional, Arteaga, S. Sonia, additional, Artiles, Ligia, additional, Coady, Sean, additional, Cooper, Lawton S., additional, Curry, Jennifer, additional, Desvigne-Nickens, Patrice, additional, Nicastro, Holly L., additional, and Rosario, Adelaida, additional

Published
2020
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18. Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies

Author

Pennells, Lisa, Kaptoge, Stephen, Wood, Angela, Sweeting, Mike, Zhao, Xiaohui, White, Ian, Burgess, Stephen, Willeit, Peter, Bolton, Thomas, Moons, Karel G M, van der Schouw, Yvonne T, Selmer, Randi, Khaw, Kay-Tee, Gudnason, Vilmundur, Assmann, Gerd, Amouyel, Philippe, Salomaa, Veikko, Kivimaki, Mika, Nordestgaard, Børge G, Blaha, Michael J, Kuller, Lewis H, Brenner, Hermann, Gillum, Richard F, Meisinger, Christa, Ford, Ian, Knuiman, Matthew W, Rosengren, Annika, Lawlor, Debbie A, Völzke, Henry, Cooper, Cyrus, Marín Ibañez, Alejandro, Casiglia, Edoardo, Kauhanen, Jussi, Cooper, Jackie A, Rodriguez, Beatriz, Sundström, Johan, Barrett-Connor, Elizabeth, Dankner, Rachel, Nietert, Paul J, Davidson, Karina W, Wallace, Robert B, Blazer, Dan G, Björkelund, Cecilia, Donfrancesco, Chiara, Krumholz, Harlan M, Nissinen, Aulikki, Davis, Barry R, Coady, Sean, Whincup, Peter H, Jørgensen, Torben, Ducimetiere, Pierre, Trevisan, Maurizio, Engström, Gunnar, Crespo, Carlos J, Meade, Tom W, Visser, Marjolein, Kromhout, Daan, Kiechl, Stefan, Daimon, Makoto, Price, Jackie F, Gómez de la Cámara, Agustin, Wouter Jukema, J, Lamarche, Benoît, Onat, Altan, Simons, Leon A, Kavousi, Maryam, Ben-Shlomo, Yoav, Gallacher, John, Dekker, Jacqueline M, Arima, Hisatomi, Shara, Nawar, Tipping, Robert W, Roussel, Ronan, Brunner, Eric J, Koenig, Wolfgang, Sakurai, Masaru, Pavlovic, Jelena, Gansevoort, Ron T, Nagel, Dorothea, Goldbourt, Uri, Barr, Elizabeth L M, Palmieri, Luigi, Njølstad, Inger, Sato, Shinichi, Monique Verschuren, W M, Varghese, Cherian V, Graham, Ian, Onuma, Oyere, Greenland, Philip, Woodward, Mark, Ezzati, Majid, Psaty, Bruce M, Sattar, Naveed, Jackson, Rod, Ridker, Paul M, Cook, Nancy R, D'Agostino, Ralph B, Thompson, Simon G, Danesh, John, Di Angelantonio, Emanuele, Simpson, Lara M, Pressel, Sara L, Couper, David J, Nambi, Vijay, Matsushita, Kunihiro, Folsom, Aaron R, Shaw, Jonathan E, Magliano, Dianna J, Zimmet, Paul Z, Wannamethee, S Goya, Willeit, Johann, Santer, Peter, Egger, Georg, Casas, Juan Pablo, Amuzu, Antointtte, Tikhonoff, Valérie, Sutherland, Susan E, Cushman, Mary, Søgaard, Anne Johanne, Håheim, Lise Lund, Ariansen, Inger, Tybjærg-Hansen, Anne, Jensen, Gorm B, Schnohr, Peter, Giampaoli, Simona, Vanuzzo, Diego, Panico, Salvatore, Balkau, Beverley, Bonnet, Fabrice, Marre, Michel, de la Cámara, Agustin Gómez, Rubio Herrera, Miguel Angel, Friedlander, Yechiel, McCallum, John, McLachlan, Stela, Guralnik, Jack, Phillips, Caroline L, Wareham, Nick, Schöttker, Ben, Saum, Kai-Uwe, Holleczek, Bernd, Tolonen, Hanna, Vartiainen, Erkki, Jousilahti, Pekka, Harald, Kennet, D’Agostino, Ralph B, Massaro, Joseph M, Pencina, Michael, Vasan, Ramachandran, Kayama, Takamasa, Kato, Takeo, Oizumi, Toshihide, Jespersen, Jørgen, Møller, Lars, Bladbjerg, Else Marie, Chetrit, A, Wilhelmsen, Lars, Lissner, Lauren, Dennison, Elaine, Kiyohara, Yutaka, Ninomiya, Toshiharu, Doi, Yasufumi, Nijpels, Giel, Stehouwer, Coen D A, Kazumasa, Yamagishi, Iso, Hiroyasu, Kurl, Sudhir, Tuomainen, Tomi-Pekka, Salonen, Jukka T, Deeg, Dorly J H, Nilsson, Peter M, Hedblad, Bo, Melander, Olle, De Boer, Ian H, DeFilippis, Andrew Paul, Verschuren, W M Monique, Watt, Graham, Tverdal, Aage, Kirkland, Susan, Shimbo, Daichi, Shaffer, Jonathan, Bakker, Stephan J L, van der Harst, Pim, Hillege, Hans L, Dallongeville, Jean, Schulte, Helmut, Trompet, Stella, Smit, Roelof A J, Stott, David J, Després, Jean-Pierre, Cantin, Bernard, Dagenais, Gilles R, Laughlin, Gail, Wingard, Deborah, Aspelund, Thor, Eiriksdottir, Gudny, Gudmundsson, Elias Freyr, Ikram, Arfan, van Rooij, Frank J A, Franco, Oscar H, Rueda-Ochoa, Oscar L, Muka, Taulant, Glisic, Marija, Tunstall-Pedoe, Hugh, Howard, Barbara V, Zhang, Ying, Jolly, Stacey, Davey-Smith, George, Can, Günay, Yüksel, Hüsniye, Nakagawa, Hideaki, Morikawa, Yuko, Miura, Katsuyuki, Ingelsson, Martin, Giedraitis, Vilmantas, Gaziano, J Michael, Shipley, Martin, Arndt, Volker, Cook, Nancy, Ibañez, Alejandro Marín, Geleijnse, Johanna M, Epidemiology, Læknadeild (HÍ), Faculty of Medicine (UI), Heilbrigðisvísindasvið (HÍ), School of Health Sciences (UI), Háskóli Íslands, University of Iceland, Pennells, Lisa [0000-0002-8594-3061], Kaptoge, Stephen [0000-0002-1155-4872], Wood, Angela [0000-0002-7937-304X], Sweeting, Michael [0000-0003-0980-8965], Zhao, Xiaohui [0000-0001-9922-2815], Burgess, Stephen [0000-0001-5365-8760], Danesh, John [0000-0003-1158-6791], Di Angelantonio, Emanuele [0000-0001-8776-6719], Apollo - University of Cambridge Repository, Nutrition and Health, APH - Aging & Later Life, APH - Societal Participation & Health, APH - Health Behaviors & Chronic Diseases, Cardiovascular Centre (CVC), Groningen Kidney Center (GKC), Groningen Institute for Organ Transplantation (GIOT), Lifestyle Medicine (LM), Life Course Epidemiology (LCE), AGEM - Endocrinology, metabolism and nutrition, Internal medicine, Epidemiology and Data Science, İÜC, Lisa, Pennell, Stephen, Kaptoge, Angela, Wood, Mike, Sweeting, Xiaohui, Zhao, Ian, White, Stephen, Burge, Peter, Willeit, Thomas, Bolton, Karel G M, Moon, Yvonne T, van der Schouw, Randi, Selmer, Kay-Tee, Khaw, Vilmundur, Gudnason, Gerd, Assmann, Philippe, Amouyel, Veikko, Salomaa, Mika, Kivimaki, Børge G, Nordestgaard, Michael J, Blaha, Lewis H, Kuller, Hermann, Brenner, Richard F, Gillum, Christa, Meisinger, Ian, Ford, Matthew W, Knuiman, Annika, Rosengren, Debbie A, Lawlor, Henry, Völzke, Cyrus, Cooper, Alejandro, Marín Ibañez, Edoardo, Casiglia, Jussi, Kauhanen, Jackie A, Cooper, Beatriz, Rodriguez, Johan, Sundström, Elizabeth, Barrett-Connor, Rachel, Dankner, Paul J, Nietert, Karina W, Davidson, Robert B, Wallace, Dan G, Blazer, Cecilia, Björkelund, Chiara, Donfrancesco, Harlan M, Krumholz, Aulikki, Nissinen, Barry R, Davi, Sean, Coady, Peter H, Whincup, Torben, Jørgensen, Pierre, Ducimetiere, Maurizio, Trevisan, Gunnar, Engström, Carlos J, Crespo, Tom W, Meade, Marjolein, Visser, Daan, Kromhout, Stefan, Kiechl, Makoto, Daimon, Jackie F, Price, Agustin, Gómez de la Cámara, J, Wouter Jukema, Benoît, Lamarche, Altan, Onat, Leon A, Simon, Maryam, Kavousi, Yoav, Ben-Shlomo, John, Gallacher, Jacqueline M, Dekker, Hisatomi, Arima, Nawar, Shara, Robert W, Tipping, Ronan, Roussel, Eric J, Brunner, Wolfgang, Koenig, Masaru, Sakurai, Jelena, Pavlovic, Ron T, Gansevoort, Dorothea, Nagel, Uri, Goldbourt, Elizabeth L M, Barr, Luigi, Palmieri, Inger, Njølstad, Shinichi, Sato, W M, Monique Verschuren, Cherian V, Varghese, Ian, Graham, Oyere, Onuma, Philip, Greenland, Mark, Woodward, Majid, Ezzati, Bruce M, Psaty, Sattar, W Tipping, Naveerobert, M Simpson, Lara, L Pressel, Sara, J Couper, David, Nambi, Vijay, Matsushita, Kunihiro, R Folsom, Aaron, E Shaw, Jonathan, J Magliano, Dianna, Z Zimmet, Paul, W Knuiman, Matthew, H Whincup, Peter, Goya Wannamethee, S, Willeit, Johann, Santer, Peter, Egger, Georg, Pablo Casas, Juan, Amuzu, Antoinette, Ben-Shlomo, Yoav, Gallacher, John, Tikhonoff, Valérie, Casiglia, Edoardo, E Sutherland, Susan, J Nietert, Paul, Cushman, Mary, M Psaty, Bruce, Johanne Søgaard, Anne, Lund Håheim, Lise, Ariansen, Inger, Tybjærg-Hansen, Anne, B Jensen, Gorm, Schnohr, Peter, Giampaoli, Simona, Vanuzzo, Diego, Panico, Salvatore, Palmieri, Luigi, Balkau, Beverley, Bonnet, Fabrice, Marre, Michel, Gómez de la Cámara, Agustin, Angel Rubio Herrera, Miguel, Friedlander, Yechiel, Mccallum, John, Mclachlan, Stela, Guralnik, Jack, L Phillips, Caroline, Khaw, Kay-Tee, Wareham, Nick, Schöttker, Ben, Saum, Kai-Uwe, Holleczek, Bernd, Nissinen, Aulikki, Tolonen, Hanna, Donfrancesco, Chiara, Vartiainen, Erkki, Jousilahti, Pekka, Harald, Kennet, B D’Agostino, Ralph, M Massaro, Joseph, Pencina, Michael, Vasan, Ramachandran, Kayama, Takamasa, Kato, Takeo, Oizumi, Toshihide, Jespersen, Jørgen, Møller, Lar, Marie Bladbjerg, Else, Chetrit, A, Rosengren, Annika, Wilhelmsen, Lar, Björkelund, Cecilia, Lissner, Lauren, Nagel, Dorothea, Dennison, Elaine, Kiyohara, Yutaka, Ninomiya, Toshiharu, Doi, Yasufumi, Rodriguez, Beatriz, Nijpels, Giel, A Stehouwer, Coen D, Sato, Shinichi, Kazumasa, Yamagishi, Iso, Hiroyasu, Goldbourt, Uri, Salomaa, Veikko, Kurl, Sudhir, Tuomainen, Tomi-Pekka, T Salonen, Jukka, Visser, Marjolein, H Deeg, Dorly J, W Meade, Tom, M Nilsson, Peter, Hedblad, Bo, Melander, Olle, H De Boer, Ian, Paul DeFilippis, Andrew, M Monique Verschuren, W, Sattar, Naveed, Watt, Graham, Meisinger, Christa, Koenig, Wolfgang, H Kuller, Lewi, Tverdal, Aage, F Gillum, Richard, A Cooper, Jackie, Kirkland, Susan, Shimbo, Daichi, Shaffer, Jonathan, Ducimetiere, Pierre, L Bakker, Stephan J, van der Harst, Pim, L Hillege, Han, J Crespo, Carlo, Amouyel, Philippe, Dallongeville, Jean, Assmann, Gerd, Schulte, Helmut, Trompet, Stella, J Smit, Roelof A, J Stott, David, T van der Schouw, Yvonne, Després, Jean-Pierre, Cantin, Bernard, R Dagenais, Gille, Laughlin, Gail, Wingard, Deborah, Trevisan, Maurizio, Aspelund, Thor, Eiriksdottir, Gudny, Freyr Gudmundsson, Elia, Ikram, Arfan, A van Rooij, Frank J, H Franco, Oscar, L Rueda-Ochoa, Oscar, Muka, Taulant, Glisic, Marija, Tunstall-Pedoe, Hugh, Völzke, Henry, V Howard, Barbara, Zhang, Ying, Jolly, Stacey, Davey-Smith, George, Can, Günay, Yüksel, Hüsniye, Nakagawa, Hideaki, Morikawa, Yuko, Miura, Katsuyuki, Njølstad, Inger, Ingelsson, Martin, Giedraitis, Vilmanta, M Ridker, Paul, Michael Gaziano, J, Kivimaki, Mika, Shipley, Martin, J Brunner, Eric, Arndt, Volker, Brenner, Hermann, Cook, Nancy, Ford, Ian, Marín Ibañez, Alejandro, M Geleijnsed, Johanna, Rod, Jackson, Paul M, Ridker, Nancy R, Cook, Ralph B, D'Agostino, Simon G, Thompson, John, Danesh, and Emanuele, Di Angelantonio

Subjects
Male, Cardiac & Cardiovascular Systems, Nutrition and Disease, Prevention and Epidemiology, PREDICTION, Áhættuþættir, 030204 cardiovascular system & hematology, GUIDELINES, 0302 clinical medicine, Risk Factors, Voeding en Ziekte, FRAMINGHAM, Discrimination, Medicine, Cardiac and Cardiovascular Systems, Blóðrásarsjúkdómar, Prospective Studies, Prospective cohort study, Non-U.S. Gov't, 1102 Cardiorespiratory Medicine and Haematology, CALIBRATION, Kardiologi, Framingham Risk Score, Emerging Risk Factors Collaboration, SCORES, Research Support, Non-U.S. Gov't, Incidence (epidemiology), Middle Aged, Cardiovascular disease, Justice and Strong Institutions, Risk prediction, ddc, 3. Good health, Cardiovascular Diseases, Meta-analysis, Cohort, Calibration, Female, Risk assessment, Cardiology and Cardiovascular Medicine, Algorithm, Life Sciences & Biomedicine, Algorithms, SDG 16 - Peace, Risk algorithms, DISEASE PREVENTION, Research Support, Risk Assessment, VALIDATION, 03 medical and health sciences, Clinical Research, Journal Article, Humans, ddc:610, Risk factor, VLAG, Aged, Science & Technology, business.industry, SDG 16 - Peace, Justice and Strong Institutions, 030229 sport sciences, R1, STATIN USE, Cardiovascular System & Hematology, Cardiovascular System & Cardiology, business, PRIMARY PREVENTION, TASK-FORCE
Abstract

Publisher's version (útgefin grein), Aims: There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after 'recalibration', a method that adapts risk algorithms to take account of differences in the risk characteristics of the populations being studied. Methods and results: Using individual-participant data on 360 737 participants without CVD at baseline in 86 prospective studies from 22 countries, we compared the Framingham risk score (FRS), Systematic COronary Risk Evaluation (SCORE), pooled cohort equations (PCE), and Reynolds risk score (RRS). We calculated measures of risk discrimination and calibration, and modelled clinical implications of initiating statin therapy in people judged to be at 'high' 10 year CVD risk. Original risk algorithms were recalibrated using the risk factor profile and CVD incidence of target populations. The four algorithms had similar risk discrimination. Before recalibration, FRS, SCORE, and PCE over-predicted CVD risk on average by 10%, 52%, and 41%, respectively, whereas RRS under-predicted by 10%. Original versions of algorithms classified 29-39% of individuals aged ≥40 years as high risk. By contrast, recalibration reduced this proportion to 22-24% for every algorithm. We estimated that to prevent one CVD event, it would be necessary to initiate statin therapy in 44-51 such individuals using original algorithms, in contrast to 37-39 individuals with recalibrated algorithms. Conclusion: Before recalibration, the clinical performance of four widely used CVD risk algorithms varied substantially. By contrast, simple recalibration nearly equalized their performance and improved modelled targeting of preventive action to clinical need., The work of the co-ordinating centre was funded by the UK Medical Research Council (G0800270), British Heart Foundation (SP/09/ 002), British Heart Foundation Cambridge Cardiovascular Centre of Excellence, UK National Institute for Health Research Cambridge Biomedical Research Centre, European Research Council (268834), and European Commission Framework Programme 7 (HEALTH-F2-2012-279233). The Emerging Risk Factor Collaboration’s website https://www.phpc.cam.ac.uk/ceu/erfc/list-of-studies/ has compiled a list provided by investigators of some of the funders of the component studies in this analysis. I.W. was supported by the Medical Research Council Unit Programme MC_UU_12023/21. M.K. is supported by the Netherlands Organization for Scientific Research (NWO) Veni grant (Veni, 91616079). J.P. is supported by Erasmus Mundus Western Balkans (ERAWEB), a project funded by the European Commission.

Published
2019

20. World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions

Author

Cardiovasculaire Epi Team 1, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cardiovasculaire Epi Team 9, Epi Methoden, Cancer, JC onderzoeksprogramma Methodologie, Kaptoge, Stephen, Pennells, Lisa, De Bacquer, Dirk, Cooney, Marie Therese, Kavousi, Maryam, Stevens, Gretchen, Riley, Leanne Margaret, Savin, Stefan, Khan, Taskeen, Altay, Servet, Amouyel, Philippe, Assmann, Gerd, Bell, Steven, Ben-Shlomo, Yoav, Berkman, Lisa, Beulens, Joline W., Björkelund, Cecilia, Blaha, Michael, Blazer, Dan G., Bolton, Thomas, Bonita Beaglehole, Ruth, Brenner, Hermann, Brunner, Eric J., Casiglia, Edoardo, Chamnan, Parinya, Choi, Yeun Hyang, Chowdry, Rajiv, Coady, Sean, Crespo, Carlos J., Cushman, Mary, Dagenais, Gilles R., D'Agostino, Ralph B., Daimon, Makoto, Davidson, Karina W., Engström, Gunnar, Ford, Ian, Gallacher, John, Gansevoort, Ron T., Gaziano, Thomas Andrew, Giampaoli, Simona, Grandits, Greg, Grimsgaard, Sameline, Grobbee, Diederick E., Gudnason, Vilmundur, Guo, Qi, Tolonen, Hanna, Humphries, Steve, Iso, Hiroyasu, Jukema, J. Wouter, Moons, Karel G.M., Cardiovasculaire Epi Team 1, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cardiovasculaire Epi Team 9, Epi Methoden, Cancer, JC onderzoeksprogramma Methodologie, Kaptoge, Stephen, Pennells, Lisa, De Bacquer, Dirk, Cooney, Marie Therese, Kavousi, Maryam, Stevens, Gretchen, Riley, Leanne Margaret, Savin, Stefan, Khan, Taskeen, Altay, Servet, Amouyel, Philippe, Assmann, Gerd, Bell, Steven, Ben-Shlomo, Yoav, Berkman, Lisa, Beulens, Joline W., Björkelund, Cecilia, Blaha, Michael, Blazer, Dan G., Bolton, Thomas, Bonita Beaglehole, Ruth, Brenner, Hermann, Brunner, Eric J., Casiglia, Edoardo, Chamnan, Parinya, Choi, Yeun Hyang, Chowdry, Rajiv, Coady, Sean, Crespo, Carlos J., Cushman, Mary, Dagenais, Gilles R., D'Agostino, Ralph B., Daimon, Makoto, Davidson, Karina W., Engström, Gunnar, Ford, Ian, Gallacher, John, Gansevoort, Ron T., Gaziano, Thomas Andrew, Giampaoli, Simona, Grandits, Greg, Grimsgaard, Sameline, Grobbee, Diederick E., Gudnason, Vilmundur, Guo, Qi, Tolonen, Hanna, Humphries, Steve, Iso, Hiroyasu, Jukema, J. Wouter, and Moons, Karel G.M.

Published
2019

21. Equalization of four cardiovascular risk algorithms after systematic recalibration:individual-participant meta-analysis of 86 prospective studies

Author

Pennells, Lisa, Kaptoge, Stephen, Wood, Angela, Sweeting, Mike, Zhao, Xiaohui, White, Ian, Burgess, Stephen, Willeit, Peter, Bolton, Thomas, Moons, Karel G. M., van der Schouw, Yvonne T., Selmer, Randi, Khaw, Kay-Tee, Gudnason, Vilmundur, Assmann, Gerd, Amouyel, Philippe, Salomaa, Veikko, Kivimaki, Mika, Nordestgaard, Borge G., Blaha, Michael J., Kuller, Lewis H., Brenner, Hermann, Gillum, Richard F., Meisinger, Christa, Ford, Ian, Knuiman, Matthew W., Rosengren, Annika, Lawlor, Debbie A., Volzke, Henry, Cooper, Cyrus, Ibanez, Alejandro Marin, Casiglia, Edoardo, Kauhanen, Jussi, Cooper, Jackie A., Rodriguez, Beatriz, Sundstrom, Johan, Barrett-Connor, Elizabeth, Dankner, Rachel, Nietert, Paul J., Davidson, Karina W., Wallace, Robert B., Blazer, Dan G., Bjorkelund, Cecilia, Donfrancesco, Chiara, Krumholz, Harlan M., Nissinen, Aulikki, Davis, Barry R., Coady, Sean, Whincup, Peter H., Jørgensen, Torben, Ducimetiere, Pierre, Trevisan, Maurizio, Engstrom, Gunnar, Crespo, Carlos J., Meade, Tomw., Visser, Marjolein, Kromhout, Daan, Kiechl, Stefan, Daimon, Makoto, Price, Jackie F., de la Camara, Agustin Gomez, Jukema, J. Wouter, Lamarche, Benoit, Onat, Altan, Simons, Leon A., Kavousi, Maryam, Ben-Shlomo, Yoav, Gallacher, John, Dekker, Jacqueline M., Arima, Hisatomi, Shara, Nawar, Tipping, RobertW., Roussel, Ronan, Brunner, Eric J., Koenig, Wolfgang, Sakurai, Masaru, Pavlovic, Jelena, Gansevoort, Ron T., Nagel, Dorothea, Goldbourt, Uri, Barr, Elizabeth L. M., Palmieri, Luigi, Njølstad, Inger, Sato, Shinichi, Verschuren, W. M. Monique, Varghese, Cherian V., Graham, Ian, Onuma, Oyere, Greenland, Philip, Woodward, Mark, Ezzati, Majid, Psaty, Bruce M., Sattar, Naveed, Jackson, Rod, Ridker, Paul M., Cook, Nancy, D'Agostino, Ralph B., Sr., Thompson, Simon G., Danesh, John, Di Angelantonio, Emanuele, Tipping, Robert W., Simpson, Lara M., Pressel, Sara L., Couper, David J., Nambi, Vijay, Matsushita, Kunihiro, Folsom, Aaron R., Shaw, Jonathan E., Magliano, Dianna J., Zimmet, Paul Z., Wannamethee, S. Goya, Willeit, Johann, Santer, Peter, Egger, Georg, Casas, Juan Pablo, Amuzu, Antointtte, Tikhonoff, Valerie, Sutherland, Susan E., Cushman, Mary, Sogaard, Anne Johanne, Haheim, Lise Lund, Ariansen, Inger, Tybjærg-Hansen, Anne, Jensen, Gorm B., Schnohr, Peter, Giampaoli, Simona, Vanuzzo, Diego, Panico, Salvatore, Balkau, Beverley, Bonnet, Fabrice, Marre, Michel, Herrera, Miguel Angel Rubio, Friedlander, Yechiel, McCallum, John, McLachlan, Stela, Guralnik, Jack, Phillips, Caroline L., Wareham, Nick, Schottker, Ben, Saum, Kai-Uwe, Holleczek, Bernd, Tolonen, Hanna, Jousilahti, Pekka, Harald, Kennet, Massaro, Joseph M., Pencina, Michael, Vasan, Ramachandran, Kayama, Takamasa, Kato, Takeo, Oizumi, Toshihide, Jespersen, Jorgen, Møller, Lars, Bladbjerg, Else Marie, Chetrit, A., Wilhelmsen, Lars, Lissner, Lauren, Dennison, Elaine, Kiyohara, Yutaka, Ninomiya, Toshiharu, Doi, Yasufumi, Nijpels, Giel, Stehouwer, Coen D. A., Kazumasa, Yamagishi, Iso, Hiroyasu, Vartiainen, Erkki, Kurl, Sudhir, Tuomainen, Tomi-Pekka, Salonen, Jukka T., Deeg, Dorly J. H., Nilsson, Peter M., Hedblad, Bo, Melander, Olle, De Boer, Ian H., DeFilippis, Andrew Paul, Watt, Graham, Verschuren, Monique, Tverdal, Aage, Kirkland, Susan, Shimbo, Daichi, Shaffer, Jonathan, Bakker, Stephan J. L., van der Harst, Pim, Hillege, Hans L., Dallongeville, Jean, Schulte, Helmut, Trompet, Stella, Smit, Roelof A. J., Stott, David J., Despres, Jean-Pierre, Cantin, Bernard, Dagenais, Gilles R., Laughlin, Gail, Wingard, Deborah, Aspelund, Thor, Eiriksdottir, Gudny, Gudmundsson, Elias Freyr, Ikram, Arfan, van Rooij, Frank J. A., Franco, Oscar H., Rueda-Ochoa, Oscar L., Muka, Taulant, Glisic, Marija, Tunstall-Pedoe, Hugh, Howard, Barbara V., Zhang, Ying, Jolly, Stacey, Davey-Smith, George, Can, Gunay, Yuksel, Husniye, Nakagawa, Hideaki, Morikawa, Yuko, Miura, Katsuyuki, Ingelsson, Martin, Giedraitis, Vilmantas, Gaziano, J. Michael, Shipley, Martin, Arndt, Volker, Geleijnse, Johanna M., Pennells, Lisa, Kaptoge, Stephen, Wood, Angela, Sweeting, Mike, Zhao, Xiaohui, White, Ian, Burgess, Stephen, Willeit, Peter, Bolton, Thomas, Moons, Karel G. M., van der Schouw, Yvonne T., Selmer, Randi, Khaw, Kay-Tee, Gudnason, Vilmundur, Assmann, Gerd, Amouyel, Philippe, Salomaa, Veikko, Kivimaki, Mika, Nordestgaard, Borge G., Blaha, Michael J., Kuller, Lewis H., Brenner, Hermann, Gillum, Richard F., Meisinger, Christa, Ford, Ian, Knuiman, Matthew W., Rosengren, Annika, Lawlor, Debbie A., Volzke, Henry, Cooper, Cyrus, Ibanez, Alejandro Marin, Casiglia, Edoardo, Kauhanen, Jussi, Cooper, Jackie A., Rodriguez, Beatriz, Sundstrom, Johan, Barrett-Connor, Elizabeth, Dankner, Rachel, Nietert, Paul J., Davidson, Karina W., Wallace, Robert B., Blazer, Dan G., Bjorkelund, Cecilia, Donfrancesco, Chiara, Krumholz, Harlan M., Nissinen, Aulikki, Davis, Barry R., Coady, Sean, Whincup, Peter H., Jørgensen, Torben, Ducimetiere, Pierre, Trevisan, Maurizio, Engstrom, Gunnar, Crespo, Carlos J., Meade, Tomw., Visser, Marjolein, Kromhout, Daan, Kiechl, Stefan, Daimon, Makoto, Price, Jackie F., de la Camara, Agustin Gomez, Jukema, J. Wouter, Lamarche, Benoit, Onat, Altan, Simons, Leon A., Kavousi, Maryam, Ben-Shlomo, Yoav, Gallacher, John, Dekker, Jacqueline M., Arima, Hisatomi, Shara, Nawar, Tipping, RobertW., Roussel, Ronan, Brunner, Eric J., Koenig, Wolfgang, Sakurai, Masaru, Pavlovic, Jelena, Gansevoort, Ron T., Nagel, Dorothea, Goldbourt, Uri, Barr, Elizabeth L. M., Palmieri, Luigi, Njølstad, Inger, Sato, Shinichi, Verschuren, W. M. Monique, Varghese, Cherian V., Graham, Ian, Onuma, Oyere, Greenland, Philip, Woodward, Mark, Ezzati, Majid, Psaty, Bruce M., Sattar, Naveed, Jackson, Rod, Ridker, Paul M., Cook, Nancy, D'Agostino, Ralph B., Sr., Thompson, Simon G., Danesh, John, Di Angelantonio, Emanuele, Tipping, Robert W., Simpson, Lara M., Pressel, Sara L., Couper, David J., Nambi, Vijay, Matsushita, Kunihiro, Folsom, Aaron R., Shaw, Jonathan E., Magliano, Dianna J., Zimmet, Paul Z., Wannamethee, S. Goya, Willeit, Johann, Santer, Peter, Egger, Georg, Casas, Juan Pablo, Amuzu, Antointtte, Tikhonoff, Valerie, Sutherland, Susan E., Cushman, Mary, Sogaard, Anne Johanne, Haheim, Lise Lund, Ariansen, Inger, Tybjærg-Hansen, Anne, Jensen, Gorm B., Schnohr, Peter, Giampaoli, Simona, Vanuzzo, Diego, Panico, Salvatore, Balkau, Beverley, Bonnet, Fabrice, Marre, Michel, Herrera, Miguel Angel Rubio, Friedlander, Yechiel, McCallum, John, McLachlan, Stela, Guralnik, Jack, Phillips, Caroline L., Wareham, Nick, Schottker, Ben, Saum, Kai-Uwe, Holleczek, Bernd, Tolonen, Hanna, Jousilahti, Pekka, Harald, Kennet, Massaro, Joseph M., Pencina, Michael, Vasan, Ramachandran, Kayama, Takamasa, Kato, Takeo, Oizumi, Toshihide, Jespersen, Jorgen, Møller, Lars, Bladbjerg, Else Marie, Chetrit, A., Wilhelmsen, Lars, Lissner, Lauren, Dennison, Elaine, Kiyohara, Yutaka, Ninomiya, Toshiharu, Doi, Yasufumi, Nijpels, Giel, Stehouwer, Coen D. A., Kazumasa, Yamagishi, Iso, Hiroyasu, Vartiainen, Erkki, Kurl, Sudhir, Tuomainen, Tomi-Pekka, Salonen, Jukka T., Deeg, Dorly J. H., Nilsson, Peter M., Hedblad, Bo, Melander, Olle, De Boer, Ian H., DeFilippis, Andrew Paul, Watt, Graham, Verschuren, Monique, Tverdal, Aage, Kirkland, Susan, Shimbo, Daichi, Shaffer, Jonathan, Bakker, Stephan J. L., van der Harst, Pim, Hillege, Hans L., Dallongeville, Jean, Schulte, Helmut, Trompet, Stella, Smit, Roelof A. J., Stott, David J., Despres, Jean-Pierre, Cantin, Bernard, Dagenais, Gilles R., Laughlin, Gail, Wingard, Deborah, Aspelund, Thor, Eiriksdottir, Gudny, Gudmundsson, Elias Freyr, Ikram, Arfan, van Rooij, Frank J. A., Franco, Oscar H., Rueda-Ochoa, Oscar L., Muka, Taulant, Glisic, Marija, Tunstall-Pedoe, Hugh, Howard, Barbara V., Zhang, Ying, Jolly, Stacey, Davey-Smith, George, Can, Gunay, Yuksel, Husniye, Nakagawa, Hideaki, Morikawa, Yuko, Miura, Katsuyuki, Ingelsson, Martin, Giedraitis, Vilmantas, Gaziano, J. Michael, Shipley, Martin, Arndt, Volker, and Geleijnse, Johanna M.

Published
2019

22. PREDICTORS OF ALL-CAUSE MORTALITY IN THE BARI 2D TRIAL IDENTIFIED BY MACHINE-LEARNING

Author

Mallick, Zyannah, primary, Dey, Amit, additional, Gu, Yuan, additional, Shalhoub, Ruba, additional, Wang, Runqiu, additional, Wu, Colin, additional, Tian, Xin, additional, Almario, Eileen Navarro, additional, Patel, Tejas, additional, Fleg, Jerome, additional, Anna, Kettermann, additional, Csako, Gyorgy, additional, Sopko, George, additional, Sviglin, Helena, additional, Cooper, Lawton, additional, Xin, Victoria, additional, Calis, Karim, additional, Gani, Nuha, additional, Chowdhury, Iffat, additional, Keith, Burkhart, additional, Szarfman, Ana, additional, Coady, Sean, additional, Pucino, Frank, additional, Rosenberg, Yves, additional, and Hasan, Ahmed, additional

Published
2019
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23. PREDICTORS OF ALL-CAUSE MORTALITY IN THE AIM-HIGH TRIAL IDENTIFIED BY MACHINE LEARNING

Author

Hoque, Laboni H., primary, Dey, Amit, additional, Gu, Yuan, additional, Xin, Victoria, additional, Shalhoub, Ruba, additional, Wang, Runqiu, additional, Wu, Colin, additional, Xin, Tian, additional, Almario, Eileen Navarro, additional, Patel, Tejas, additional, Fleg, Jerome, additional, Kettermann, Anna, additional, Csako, Gyorgy, additional, Sopko, George, additional, Sviglin, Helena, additional, Dandi, Gauri, additional, Gani, Nuha, additional, Chowdhury, Iffat, additional, Burkhart, Keith, additional, Szarfman, Ana, additional, Coady, Sean, additional, Mehta, Nehal, additional, Pucino, Frank, additional, Rosenberg, Yves, additional, and Hasan, Ahmed, additional

Published
2019
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26. Letters

Author

Imber, David G., Obler, Charles, Carrell, Greg, Coates, Jon C., Adams, Steven, Brown, Matt, Calloway, Frank, Bertolini, Robert J., Hess, James D., Sita, Lenny, Peele, Stephen, Safuto, Vincent F., Donohue, Brian, Downie, John, Henry, David, Stoutt, Glenn R., Jr., Coady, Sean, Stanford, Geoff, Roberts, Gary M., Bales, John, Prager, Michael, Himmelman, James, Hanson, Lloyd, Fuller, Michael J., Neumann, Sally, Dulaney, Emmett, Weaver, Philip C., Devreaux, Marc, Waldman, Zev, and Gilchrist, Sandra F.

Published
1993

27. Government policies and programs affecting tobacco production and trade in major tobacco trading nations

Author

Coady, Sean, Pompelli, Greg, and Grise, Verner N.

Subjects
Turkey -- Economic policy, Japan -- Economic policy, Argentina -- Economic policy, United States -- Economic policy, South Korea -- Economic policy, Zimbabwe -- Economic policy, Brazil -- Economic policy, India -- Economic policy, Tobacco industry -- International trade -- Laws, regulations and rules -- Political aspects, Agricultural productivity -- Laws, regulations and rules -- Political aspects, Government regulation, Agricultural industry, Business, European Union -- Economic policy
Abstract

Abstract: Government intervention influences the production and trade of most of the world's unmanufactured tobacco. This article summarizes government policies and intervention in eight major tobacco trading nations and the [...]

Published
1991

28. Abstract 17059: Re-Use of Clinical Trial Data From the NHLBI Data Repository (BioLINCC) for Patient-Level Meta-Analyses of Cardiovascular Outcomes: Challenges and Opportunities

Author

Sviglin, Helena, primary, Dandi, Gauri, additional, Navarro Almario, Eileen, additional, Patel, Tejas, additional, Wu, Colin O, additional, Tian, Xin, additional, Csako, Gyorgy, additional, Shamsuzzaman, Md, additional, Tesfaldet, Bereket, additional, Fleg, Jerome, additional, Kettermann, Anna, additional, Gandotra, Charu, additional, Sopko, George, additional, Cooper, Lawton, additional, Coady, Sean, additional, Banerjee, Avantika, additional, Farooque, Nashwan, additional, Hoque, Laboni, additional, Cure, Carlos, additional, Kirby, Ruth, additional, Liu, Lijuan, additional, Chen, Jue, additional, Yan, Ye, additional, Chowdhury, Iffat, additional, Burkhart, Keith, additional, Calis, Karim, additional, Leifer, Eric, additional, Szarfman, Ana, additional, Domanski, Michael, additional, Pucino, Frank, additional, Rosenberg, Yves, additional, and Hasan, Ahmed A, additional

Published
2018
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29. SEX DIFFERENCES IN CARDIOVASCULAR DISEASE OUTCOMES IN RESPONSE TO FENOFIBRATE THERAPY IN TYPE 2 DIABETIC PATIENTS IN THE ACCORD LIPID STUDY

Author

Banerjee, Avantika, primary, Patel, Tejas, additional, Csako, Gyorgy, additional, Dodge, Andrew, additional, Navarro, Eileen, additional, Wu, Colin O., additional, Bereket, Tesfaldet, additional, Shamsuzzaman, Md, additional, Fleg, Jerome, additional, Gandotra, Charu, additional, Sopko, George, additional, Sviglin, Helena, additional, Dandi, Gauri, additional, Coady, Sean, additional, Farooque, Nashwan, additional, Cooper, Lawton, additional, Chowdhury, Iffat, additional, Szarfman, Ana, additional, Calis, Karim, additional, Burkhart, Keith, additional, Cure, Carlos, additional, Pucino, Frank, additional, Rosenberg, Yves, additional, and Hasan, Ahmed, additional

Published
2018
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31. RISK OF HOSPITALIZATION OR DEATH DUE TO HEART FAILURE WITH INTENSIVE GLUCOSE-LOWERING THERAPY IN DIABETIC WOMEN: SUBGROUP ANALYSES BY HISTORY OF CARDIOVASCULAR DISEASE IN THE ACCORD TRIAL

Author

Patel, Tejas, primary, Tesfaldet, Bereket, additional, Almario, Eileen Navarro, additional, Csako, Gyorgy, additional, Sopko, George, additional, Fleg, Jerome, additional, Kirby, Ruth, additional, Gandotra, Charu, additional, Sviglin, Helena, additional, Burkhart, Keith, additional, Calis, Karim, additional, Chen, Jue, additional, Cooper, Lawton, additional, Pucino, Frank, additional, Amin, Neha, additional, Chang, Henry, additional, Coady, Sean, additional, Nickens, Patrice Desvigne, additional, Kaufmann, Peter, additional, Leifer, Eric, additional, Liu, Lijuan, additional, Raman, Subha, additional, Rosenberg, Yves, additional, and Hasan, Ahmed, additional

Published
2017
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33. Impact of National Heart, Lung, and Blood Institute–Supported Cardiovascular Epidemiology Research, 1998 to 2012

Author

Fabsitz, Richard R., primary, Papanicolaou, George J., additional, Sholinsky, Phyliss, additional, Coady, Sean A., additional, Jaquish, Cashell E., additional, Nelson, Cheryl R., additional, Olson, Jean L., additional, Puggal, Mona A., additional, Purkiser, Kevin L., additional, Srinivas, Pothur R., additional, Wei, Gina S., additional, Wolz, Michael, additional, and Sorlie, Paul D., additional

Published
2015
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36. 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

Author

Goff, David C., primary, Lloyd-Jones, Donald M., additional, Bennett, Glen, additional, Coady, Sean, additional, D’Agostino, Ralph B., additional, Gibbons, Raymond, additional, Greenland, Philip, additional, Lackland, Daniel T., additional, Levy, Daniel, additional, O’Donnell, Christopher J., additional, Robinson, Jennifer G., additional, Schwartz, J. Sanford, additional, Shero, Susan T., additional, Smith, Sidney C., additional, Sorlie, Paul, additional, Stone, Neil J., additional, and Wilson, Peter W. F., additional

Published
2014
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