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A series of newly synthesized analogs (10a-y) were prepared from phenolic aldehydes such as Vanillin and salicaldehyde. The synthesized analogs were characterized by using different spectral techniques such as FTIR, ¹NMR, 13C NMR and Mass spectroscopy and evaluated against In vitro cancer cell lines such as MCF-7 and HeLa. The result achieved depicted that the phenolic aldehyde vanillin bearing electron donating substituent's exhibited more promising results as compared to salicaldehyde (Phenolic aldehyde). The comparative study of anticancer evaluation based on the in vitro study, which clearly signified that vanillin structure has OCH3 (Methoxy group) which is different from salicaldehyde (Which doesn't contain methoxy group). This difference based on the presence of electron donating group methoxy (OCH3) displayed the remarkable anticancer results. This research article based on the comparative anticancer study of 4-Thiazolidinone having thiadiazole moiety derived from two different phenolic aldehydes like Vanillin and salicaldehyde against cancer cell lines such as MCF-7 and HeLa. [ABSTRACT FROM AUTHOR]

This paper reports on the effect of varying concentration of erbium (Er3+) on the (70‐x/2) TeO2 − (20‐x/2) B2O3 −10 ZnO − x Er2O3 (where x = 0, 0.5, 1.0, 2.0, 2.5 mol.%) system, fabricated using the conventional melt quenching technique. The impact of Er3+ on the structural, physical, and optical properties of these zinc borotellurite glasses is investigated using Fourier transform infrared spectroscopy (FTIR), density measurements and UV–vis spectroscopy. The amorphous nature is confirmed using X‐Ray diffraction. FTIR results reveal that the glass is formed of fundamental borate and tellurite network units. The addition of Er2­O3 results in the formation of TeO3 at the expense of Te‐O‐Te linkage. The UV–vis spectroscopy results show that Er3+ enter the glass matrix showing absorption peaks corresponding to 4f‐4f transitions of trivalent Erbium ions (Er3+) from ground state 4I15/2 to the excited states 4F5/2, 4F7/2, 2H11/2, 4S3/2, 4F9/2, 4I9/2, 4I11/2, and 4I13/2. The optical band gap tends to decrease and refractive index increases with the increase in Er3+ concentration hence making these materials more efficient for the optical devices such as light emitting devices and image sensors. [ABSTRACT FROM AUTHOR]

This paper reports on the effect of varying concentration of erbium (Er3+) on the (70‐x/2) TeO2 − (20‐x/2) B2O3 −10 ZnO − x Er2O3 (where x = 0, 0.5, 1.0, 2.0, 2.5 mol.%) system, fabricated using the conventional melt quenching technique. The impact of Er3+ on the structural, physical, and optical properties of these zinc borotellurite glasses is investigated using Fourier transform infrared spectroscopy (FTIR), density measurements and UV–vis spectroscopy. The amorphous nature is confirmed using X‐Ray diffraction. FTIR results reveal that the glass is formed of fundamental borate and tellurite network units. The addition of Er2­O3 results in the formation of TeO3 at the expense of Te‐O‐Te linkage. The UV–vis spectroscopy results show that Er3+ enter the glass matrix showing absorption peaks corresponding to 4f‐4f transitions of trivalent Erbium ions (Er3+) from ground state 4I15/2 to the excited states 4F5/2, 4F7/2, 2H11/2, 4S3/2, 4F9/2, 4I9/2, 4I11/2, and 4I13/2. The optical band gap tends to decrease and refractive index increases with the increase in Er3+ concentration hence making these materials more efficient for the optical devices such as light emitting devices and image sensors. [ABSTRACT FROM AUTHOR]

Background: Neuraxial anesthesia greatly expands the anesthesiologist armamentarium, providing alternatives to general anesthesia, especially in the lower abdominal surgeries. Clonidine, an alpha-2 adrenergic agonist, has a variety of actions, including potentiation of effects of local anesthetics. This study was undertaken to assess the degree of sensory and motor block and postoperative analgesia provided by low dose (50 mcg) intrathecal clonidine admixed with bupivacaine. Aims: The aim of this study is to establish efficacy and safety of intrathecal clonidine as adjuvant to bupivacaine. Settings and Design: The type of the study was double-blind randomized trial. Materials and Methods: Hundred patients were randomly allocated in two groups, A and B. Group A received bupivacaine 0.5%, 3 ml with placebo (normal saline 0.33 ml) and Group B, bupivacaine 0.5%, 3 ml with clonidine 50 µg (0.33 ml). Statistical Analysis Used: Statistical Package for Social Sciences version 15.0 statistical analysis software. Results: Mean duration of motor block was significantly higher in Group B (280.80 ± 66.88 min) as compared with Group A (183.60 ± 77.06 min). Significant difference in duration of sensory block was noted between Group B (295.20 ± 81.17 min) and Group A (190.80 ± 86.94 min). Duration of postoperative analgesia was significantly higher in Group B as compared to Group A (551.06 ± 133.64 min and 254.80 ± 84.19 min respectively). Mean visual analog scale scores at different time intervals were significantly lower in the study group (except for 4-h time interval), but the control group had better hemodynamic stability as compared with study group. Conclusion:The findings in this study suggested that use of clonidine 50 µg added to bupivacaine for spinal anesthesia effectively increased the duration of sensory block, duration of motor block, and duration of analgesia. [ABSTRACT FROM AUTHOR]

We present recent developments of our core technologies targeted towards solution based OLED device manufacturing including non-aqueous (NQ) hole injection layer and solution processed hole transport layer. We demonstrate low voltage, and long lifetime devices with non-aqueous hole injection layer. Also, comparable performance with our intractable solution processed HTL versus NPB vapor HTL has been demonstrated in vapor WOLED devices in combination with our NQ hole injection layer technology. [ABSTRACT FROM AUTHOR]

We demonstrate high efficiency white organic light-emitting devices with two adjacent emissive layers each doped with three phosphorescent emitters (blue, green, and red). Efficient charge and exciton confinement is realized by employing charge transport layers with high triplet energy, leading to a maximum external quantum efficiency of (19±1)%. Using the p-i-n device structure, we have achieved a peak power efficiency of (40±2) lm/W and (36±2) lm/W at 100 cd/m2, a color rendering index of 79, and Commission Internationale de L’Eclairage coordinates of (0.37, 0.40) for the white light emission. [ABSTRACT FROM AUTHOR]

We report on very high efficiency deep-blue phosphorescent organic light-emitting devices (PHOLEDs) based on iridium(III) bis(4′,6′-difluorophenylpyridinato)tetrakis(1-pyrazolyl)borate (FIr6). Dual emissive layers consisting of an N,N′-dicarbazolyl-3,5-benzene layer doped with 4 wt % FIr6 and a p-bis(triphenylsilyly)benzene layer doped with 25 wt % FIr6 were employed to maximize exciton generation on FIr6 molecules. Combined with the p-i-n device structure, we achieved a low turn-on voltage of 3.2 V and very high power efficiencies of 25±2 lm/W at 100 cd/m2 and 20±2 lm/W at 1000 cd/m2 for such deep-blue PHOLEDs with peak emission at a wavelength of 458 nm. [ABSTRACT FROM AUTHOR]