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7. RF44 OUTCOME AFTER BILATERAL INTERNAL MAMMARY ARTERY GRAFTING IN HIGH- AND LOW-VOLUME HOSPITALS: AN ANALYSIS OF THE E-CABG REGISTRY

Author

Saccocci, M., Perotti, A., Reichart, D., Gatti, G., Faggian, G., Onorati, F., Feo, M. De, Chocron, S., Dalen, M., Santarpino, G., Rubino, A.S., Maselli, D., Gherli, R., Salsano, A., Nicolini, F., Zanobini, M., Bounader, K., Seccareccia, F., Rosato, S., Tauriainen, T., Mariscalco, G., Ruggieri, V.G., and Biancari, F.

Published
2018
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8. OC87 VALUE OF SCREENING ASYMPTOMATIC CAROTID ARTERY STENOSIS PRIOR TO CORONARY ARTERY BYPASS GRAFTING: ANALYSIS OF THE E-CABG REGISTRY

Author

Salsano, A., Santarpino, G., Santini, F., Nicolini, F., De Feo, M., Dalén, M., Fischlein, T., Perrotti, A., Reichart, D., Gatti, G., Onorati, F., Franzese, I., Faggian, G., Bancone, C., Chocron, S., Khodabandeh, S., Rubino, A.S., Maselli, D., Nardella, S., Gherli, R., Zanobini, M., Saccocci, M., Bounader, K., Rosato, S., Tauriainen, T., Mariscalco, G., Airaksinen, J., Ruggieri, V.G., and Biancari, F.

Published
2018
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9. OC88 COMPARATIVE ANALYSIS OF PROTHROMBIN COMPLEX CONCENTRATE AND FRESH FROZEN PLASMA IN THE MANAGEMENT OF PERIOPERATIVE BLEEDING AFTER CORONARY ARTERY BYPASS GRAFTING

Author

Salsano, A., Mariscalco, G., Santini, F., Ruggieri, V.G., Perrotti, A., Chocron, S., Gherli, R., Reichart, D., Demal, T., Faggian, G., Franzese, I., Dalén, M., Santarpino, G., Fischlein, T., Rubino, A.S., Maselli, D., Nardella, S., Nicolini, F., Saccocci, M., Gatti, G., Bounader, K., Rosato, S., Kinnunen, E., De Feo, M., Tauriainen, T., Onorati, F., and Biancari, F.

Published
2018
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10. ESICM LIVES 2016: part two: Milan, Italy. 1–5 October 2016

Author

Sivakumar, S., Taccone, F. S., Desai, K. A., Lazaridis, C., Skarzynski, M., Sekhon, M., Henderson, W., Griesdale, D., Chapple, L., Deane, A., Williams, L., Strickland, R., Lange, K., Heyland, D., Chapman, M., Rowland, M. J., Garry, P., Westbrook, J., Corkill, R., Antoniades, C. A., Pattinson, K. T., Fatania, G., Strong, A. J., Myers, R. B., Lazaridis, C., Jermaine, C. M., Robertson, C. S., Rusin, C. G., Hofmeijer, J., Sondag, L., Tjepkema-Cloostermans, M. C., Beishuizen, A., Bosch, F. H., van Putten, M. J. A. M., Carteron, L., Patet, C., Solari, D., Oddo, M., Ali, M. A., Dias, C., Almeida, R., Vaz-Ferreira, A., Silva, J., Monteiro, E., Cerejo, A., Rocha, A. P., Elsayed, A. A., Abougabal, A. M., Beshey, B. N., Alzahaby, K. M., Pozzebon, S., Ortiz, A. Blandino, Cristallini, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Taccone, F. S., Hravnak, M., Yousef, K., Chang, Y., Crago, E., Friedlander, R. M., Abdelmonem, S. A., Tahon, S. A., Helmy, T. A., Meligy, H. S., Puig, F., Dunn-Siegrist, I., Pugin, J., Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Tomar, D. S., Shafi, M., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Papakrivou, E. E., Makris, D., Manoulakas, E., Tsolaki, B., Karadodas, B., Zakynthinos, E., Garcia, I. Palacios, Martin, A. Diaz, Encinares, V. Sanchez, Ibañez, M. Pachón, Montero, J. Garnacho, Labrador, G., Cangueiro, T. Cebrero, Poulose, V., Koh, J., Kam, J. W., Yeter, H., Kara, A., Aktepe, O., Topeli, A., Tsolakoglou, I., Intas, G., Stergiannis, P., Kolaros, A. A., Chalari, E., Athanasiadou, E., Martika, A., Fildisis, G., Faivre, V., Mengelle, C., Favier, B., Payen, D., Poppe, A., Winkler, M. S., Mudersbach, E., Schreiber, J., Wruck, M. L., Schwedhelm, E., Kluge, S., Zöllner, C., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., la Torre, A. García-de, de la Torre-Prados, M. V., Tsvetanova-Spasova, T., Nuevo-Ortega, P., Rueda-Molina, C., Fernández-Porcel, A., Camara-Sola, E., Salido-Díaz, L., García-Alcántara, A., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, D. E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., Suberviola, B., Riera, J., Rellan, L., Sanchez, M., Robles, J. C., Lopez, E., Vicente, R., Miñambres, E., Santibañez, M., Le Guen, M., Moore, J., Mason, N., Windpassinger, M., Plattner, O., Mascha, E., Sessler, D. I., Research, Outcomes, Melia, U., Fontanet, J., van den Berg, J. P., Struys, M. M. R. F., Vereecke, H. E. M., Jensen, E. W., Rood, P. J. T., van de Schoor, F., van Tertholen, K., Pickkers, P., van den Boogaard, M., Beardow, Z. J., Redhead, H., Paramasivam, K., Numan, T., van den Boogaard, M., Kamper, A. M., Rood, P., Peelen, L. M., Zeman, P. M., Slooter, A. J., van Ewijk, C. E., Jacobs, G. E., Girbes, A. R. J., Myatra, S. N., Harish, M. M., Prabu, N. R., Siddiqui, S., Kulkarni, A. P., Divatia, J. V., Murbach, L. D., Leite, M. A., Osaku, E. F., Costa, C. R. L. M., Pelenz, M., Neitzke, N. M., Moraes, M. M., Jaskowiak, J. L., Silva, M. M. M., Zaponi, R. S., Abentroth, L. R. L., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Hernández-Sánchez, N., Sánchez-Hurtado, L. A., García-Guillen, F. J., Ñamendys-Silva, S. A., Maghsoudi, B., Emami, M., Khosravi, M. B., Zand, F., Tabatabaie, H. R., Masjedi, M., Sabetiyan, G., Mokri, A., Troubleyn, J., Diltoer, M., Jacobs, R., Nguyen, D. N., De Waele, E., De Regt, J., Honoré, P. M., Van Gorp, V., Spapen, H. D., Contreras, R. S., Toapanta, N. D., Moreno, G., Sabater, J., Torrado, H., Gonzalez, M., Marin, M., Farigola, E., Gonzalez, A., Fernandez, J., Vera, A., Gisbert, X., Juliá, C., Uya, J., Corral, L., Elias-Jones, I., Gemmell, L., MacKay, A., Randall, D., Adwaney, A., Blunden, M., Prowle, J. R., Kirwan, C. J., Thomas, N., Martin, A., Owen, H., Darwin, L., Conway, D., Atkinson, D., Sharman, M., Moore, J., Barbanti, C., Amour, J., Gaudard, P., Rozec, B., Mauriat, P., M’rini, M., Leger, P. L., Cambonie, G., Liet, J. M., Girard, C., Laroche, S., Damas, P., Assaf, Z., Loron, G., Lecourt, L., Pouard, P., Randall, D., Adwaney, A., Blunden, M., Prowle, J.R., Kirwan, C. J., Kim, S. H., Na, S., Kim, J., Oh, S. Y., Jung, C. W., Yoo, S. H., Min, S. H., Chung, E. J., Lee, H., Lee, N. J., Lee, K. W., Suh, K. S., Ryu, H. G., Marshall, D. C., Goodson, R. J., Salciccioli, J. D., Shalhoub, J., Potter, E. K., Kirk-Bayley, J., Karanjia, N. D., Forni, L. G., Creagh-Brown, B. C., Bossy, M., Nyman, M., Tailor, A., Creagh-Brown, B., D’Antini, D., Spadaro, S., Valentino, F., Sollitto, F., Cinnella, G., Mirabella, L., Calvo, F. J. Redondo, Bejarano, N., Padilla, D., Baladron, V., Villajero, P., Villazala, R., Redondo, J., Yuste, A. S., Liu, J., Shen, F., Teboul, J. L., Anguel, N., Beurton, A., Bezaz, N., Richard, C., Monnet, X., Fossali, T., Colombo, R., Ottolina, D., Rossetti, M., Mazzucco, C., Marchi, A., Porta, A., Catena, E., Tollisen, K. H., Andersen, G. Ø., Heyerdahl, F., Jacobsen, D., de Waard, M. C., Girbes, A. R. J., van IJzendoorn, M. C. O., Buter, H., Kingma, W. P., Navis, G. J., Boerma, E. C., Rulisek, J., Balik, M., Zacharov, S., Kim, H. S., Jeon, S. J., Namgung, H., Lee, E., Lee, E., Cho, Y. J., Lee, Y. J., Huang, A., Cioccari, L., Luethi, N., Mårtensson, J., Bellomo, R., Forsberg, M., Edman, G., Höjer, J., Forsberg, S., Freile, M. T. Chiquito, Hidalgo, F. N., Molina, J. A. Martinez, Lecumberri, R., Rosselló, A. Figuerola, Travieso, P. Medrano, Leon, G. Tuero, Sanchez, J. Gonzalez, Frias, L. Sahuquillo, Rosello, D. Balsells, Verdejo, J. A. Garcia, Serrano, J. A. Noria, Winterwerp, D., van Galen, T., Vazin, A., Karimzade, I., Zand, A., Ozen, E., Ekemen, S., Akcan, A., Sen, E., Yelken, B. Buyukkidan, Kureshi, N., Fenerty, L., Thibault-Halman, G., Erdogan, M., Walling, S., Green, R. S., Clarke, D. B., Briassoulis, P., Kalimeris, K., Ntzouvani, A., Nomikos, T., Papaparaskeva, K., Politi, E., Kostopanagiotou, G., Crewdson, K., Rehn, M., Weaver, A., Brohi, K., Lockey, D., Wright, S., Thomas, K., Baker, C., Mansfield, L., Stafford, V., Wade, C., Watson, G., Bryant, A., Chadwick, T., Shen, J., Wilkinson, J., Furneval, J., Henderson, A., Hugill, K., Howard, P., Roy, A., Bonner, S., Baudouin, S., Ramírez, C. Sánchez, Escalada, S. Hípola, Viera, M. A. Hernández, Santana, M. Cabrera, Balcázar, L. Caipe, Monroy, N. Sangil, Campelo, F. Artiles, Vázquez, C. F. Lübbe, Santana, P. Saavedra, Santana, S. Ruiz, Carteron, L., Patet, C., Quintard, H., Solari, D., Bouzat, P., Oddo, M., Wollersheim, T., Malleike, J., Haas, K., Carbon, N., Schneider, J., Birchmeier, C., Fielitz, J., Spuler, S., Weber-Carstens, S., Enseñat, L., Pérez-Madrigal, A., Saludes, P., Proença, L., Gruartmoner, G., Espinal, C., Mesquida, J., Huber, W., Eckmann, M., Elkmann, F., Gruber, A., Lahmer, T., Mayr, U., Herner, A., Schellnegger, R., Schneider, J., Schmid, R. M., Ayoub, W., Samy, W., Esmat, A., Battah, A., Mukhtar, S., Mongkolpun, W., Cortés, D. Orbegozo, Cordeiro, C. P. R., Vincent, J. L., Creteur, J., Funcke, S., Groesdonk, H., Saugel, B., Wagenpfeil, G., Wagenpfeil, S., Reuter, D. A., Fernandez, M. M., Fernandez, R., Magret, M., González-Castro, A., Bouza, M. T., Ibañez, M., García, C., Balerdi, B., Mas, A., Arauzo, V., Añón, J. M., Ruiz, F., Ferreres, J., Tomás, R., Alabert, M., Tizón, A. I., Altaba, S., Llamas, N., Goligher, E C., Fan, E., Herridge, M., Vorona, S., Sklar, M., Dres, M., Rittayamai, N., Lanys, A., Urrea, C., Tomlinson, G., Reid, W. D., Rubenfeld, G. D., Kavanagh, B. P., Brochard, L. J., Ferguson, N. D., Neto, A. Serpa, de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Guérin, C., Papazian, L., Reignier, J., Ayzac, L., Loundou, A., Forel, J. M., Rolland-Debord, C., Bureau, C., Poitou, T., Clavel, M., Perbet, S., Terzi, N., Kouatchet, A., Similowski, T., Demoule, A., Hunfeld, N., Trogrlic, Z., Ladage, S., Osse, R. J., Koch, B., Rietdijk, W., Devlin, J., van der Jagt, M., Picetti, E., Ceccarelli, P., Mensi, F., Malchiodi, L., Risolo, S., Rossi, I., Antonini, M. V., Servadei, F., Caspani, M. L., Roquilly, A., Lasocki, S., Seguin, P., Geeraerts, T., Perrigault, P. F., Dahyot-Fizelier, C., Paugam-Burtz, C., Cook, F., Cinotti, R., dit Latte, D. Demeure, Mahe, P. J., Fortuit, C., Feuillet, F., Asehnoune, K., Marzorati, C., Spina, S., Scaravilli, V., Vargiolu, A., Riva, M., Giussani, C., Sganzerla, E., Citerio, G., Barbadillo, S., de Molina, F. J. González, Álvarez-Lerma, F., Rodríguez, A., Zakharkina, T., Martin-Loeches, I., Matamoros, S., Povoa, P., Torres, A., Kastelijn, J., Hofstra, J. J., de Jong, M., Schultz, M., Sterk, P., Artigas, A., Bos, L. J., Moreau, A. S., Martin-Loeches, I., Povoa, P., Salluh, J., Rodriguez, A., Nseir, S., de Jong, E., van Oers, J. A., Beishuizen, A., Girbes, A. R. J., Nijsten, M. W. N., de Lange, D. W., Bonvicini, D., Labate, D., Benacchio, L., Olivieri, A., Pizzirani, E., Lopez-Delgado, J. C., Gonzalez-Romero, M., Fuentes-Mila, V., Berbel-Franco, D., Romera-Peregrina, I., Martinez-Pascual, A., Perez-Sanchez, J., Abellan-Lencina, R., Ávila-Espinoza, R. E., Moreno-Gonzalez, G., Sbraga, F., Griffiths, S., Grocott, M. P. W., Creagh-Brown, B., Doyle, J., Wilkerson, P., Soon, Y., Huddart, S., Dickinson, M., Riga, A., Zuleika, A., Miyamoto, K., Kawazoe, Y., Morimoto, T., Yamamoto, T., Fuke, A., Hashimoto, A., Koami, H., Beppu, S., Katayama, Y., Ito, M., Ohta, Y., Yamamura, H., Rygård, S. L., Holst, L B., Wetterslev, J., Johansson, P. I., Perner, A., Soliman, I. W., de Lange, D. W., van Dijk, D., van Delden, J. J. M., Cremer, O. L., Slooter, A. J. C., Peelen, L. M., McWilliams, D., Snelson, C., Neves, A. Das, Loudet, C. I., Busico, M., Vazquez, D., Villalba, D., Veronesi, M., Lischinsky, A., López, F. J. L., Mori, L. Benito, Plotnikow, G., Díaz, A., Giannasi, S., Hernandez, R., Krzisnik, L., Cecotti, C., Viola, L., Lopez, R., Sottile, J. P., Benavent, G., Estenssoro, E., Chen, C. M., Lai, C. C., Cheng, K. C., Chou, W., Chan, K. S., Roeker, L. E., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Weijs, P. J. M., Mogensen, K. M., Rawn, J. D., Robinson, M. K., Christopher, K. B., Tang, Z., Qiu, C., Ouyang, B., Cai, C., Guan, X., Regueira, T., Cea, L., Carlos, S. Juan, Elisa, B., Puebla, C., Vargas, A., Poulsen, M. K., Thomsen, L. P., Kjærgaard, S., Rees, S. E., Karbing, D. S., Wollersheim, T., Frank, S., Müller, M. C., Carbon, N. M., Skrypnikov, V., Pickerodt, P. A., Falk, R., Mahlau, A., Weber-Carstens, S., Lee, A., Inglis, R., Morgan, R., Barker, G., Kamata, K., Abe, T., Saitoh, D., Tokuda, Y., Green, R. S., Butler, M. B., Erdogan, M., Hwa, H. Tae, Gil, L. Jae, Vaquero, R. Hernández, Rodriguez-Ruiz, E., Lago, A. Lopez, Allut, J. L. Garcia, Gestal, A. Estany, Gonzalez, M. A. Garcia, Thomas-Rüddel, D. O., Schwarzkopf, D., Fleischmann, C., Reinhart, K., Suwanpasu, S., Sattayasomboon, Y., Filho, N. M. Filgueiras, Oliveira, J. C. A., Ballalai, C. S., De Lucia, C. V., Araponga, G. P., Veiga, L. N., Silva, C. S., Garrido, M. E., Ramos, B. B., Ricaldi, E. F., Gomes, S. S., Gemmell, L., MacKay, A., Wright, C., Docking, R. I., Doherty, P., Black, E., Stenhouse, P., Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., Moodie, S., Horowitz, M., Shaw, J. E., Deane, A. M., Yatabe, T., Inoue, S., Sakaguchi, M., Egi, M., Abdelhamid, Y. Ali, Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., Moodie, S., Horowitz, M., Shaw, J. E., Deane, A. M., Hokka, M., Egi, M., Mizobuchi, S., Kar, P., Plummer, M., Abdelhamid, Y. Ali, Giersch, E., Summers, M., Hatzinikolas, S., Heller, S., Chapman, M., Jones, K., Horowitz, M., Deane, A., Schweizer, R., Jacquet-Lagreze, M., Portran, P., Junot, S., Allaouchiche, B., Fellahi, J. L., Guerci, P., Ergin, B., Kapucu, A., Ince, C., Cioccari, L., Luethi, N., Crisman, M., Bellomo, R., Mårtensson, J., Shinotsuka, C. Righy, Fagnoul, D., Brasseur, A., Orbegozo, D., Vincent, J. L., Preiser, J. C., Preiser, J. C., Lheureux, O., Thooft, A., Brimioulle, S., Vincent, J. L., Iwasaka, H., Tahara, S., Nagamine, M., Ichigatani, A., Cabrera, A. Rugerio, Zepeda, E. Monares, Granillo, J. Franco, Sánchez, J. S. Aguirre, Montoya, A. A. Tanaka, Montenegro, A. Pedraza, Blanco, G. A. Gálvez, Robles, C. M. Coronado, Drolz, A., Horvatits, T., Roedl, K., Rutter, K., Kluge, S., Funk, G. C., Schneeweiss, B., Fuhrmann, V., Sabetian, G., Pooresmaeel, F., Zand, F., Ghaffaripour, S., Farbod, A., Tabei, H., Taheri, L., Anandanadesan, R., Metaxa, V., Teixeira, C., Pereira, S. M., Hernández-Marrero, P., Carvalho, A. S., Beckmann, M., Hartog, C. S., Schwarzkopf, D., Raadts, A., Robertsen, A., Førde, R., Skaga, N. O., Helseth, E., Honeybul, S., Ho, K., Lopez, P. Martinez, Gonzalez, M. Nieto, Ortega, P. Nuevo, Sola, E. Camara, Spasova, T., de la Torre-Prados, M. V., Kopecky, O., Rusinova, K., Waldauf, P., Cepeplikova, Z., Balik, M., Domínguez, J. Palamidessi, Almudevar, P. Matia, Carmona, S. Alcántara, Muñoz, J. J. Rubio, Castañeda, D. Palacios, Abellán, A. Naharro, Villamizar, P. Rodríguez, Ramos, J. Veganzones, Pérez, L. Pérez, Lucendo, A. Pérez, Ejarque, M. Camós, Estella, A., Camps, V. Lopez, Martín, M. C., Masnou, N., Barbosa, S., Varela, A., Palma, I., Cristina, L., Nunes, E., Pereira, I., Campello, G., Granja, C., Pande, R., Pandey, M., Varghese, S., Chanu, M., Van Dam, M. J., Ter Braak, E. W. M. T., Estella, A., Gracia, M., Viciana, R., Recuerda, M., Fontaiña, L. Perez, Tharmalingam, B., Kovari, F., Rose, L., Mcginlay, M., Amin, R., Burns, K., Connolly, B., Hart, N., Jouvet, P., Katz, S., Leasa, D., Mawdsley, C., Mcauley, D., Schultz, M., Blackwood, B., Denham, S., Worrall, R., Arshad, M., Isherwood, P., Khadjibaev, A., Sabirov, D., Rosstalnaya, A., Parpibaev, F., Sharipova, V., Blanco, G. A. Galvez, Guzman, C. I. Olvera, Sánchez, J. S. Aguirre, Granillo, J. Franco, Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Shafi, M., Tomar, D. S., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Cha, Y. S., Lee, S. J., Tyagi, N., Rajput, R. K., Taneja, S., Singh, V. K., Sharma, S. C., Mittal, S., Rao, B. K., Ayachi, J., Fraj, N., Romdhani, S., Khedher, A., Meddeb, K., Sma, N., Azouzi, A., Bouneb, R., Chouchene, I., El Ghardallou, M., Boussarsar, M., Jennings, R., Walter, E., Ribeiro, J. M., Moniz, I., Marçal, R., Santos, A. C., Candeias, C., e Silva, Z. Costa, Gomez, S. E. Zamora, Nieto, O. R. Perez, Gonzalez, J. A. Castanon, Cuellar, A. I. Vasquez, Mildh, H., Pettilä, V., Korhonen, A. M., Karlsson, S., Ala-Kokko, T., Reinikainen, M., Vaara, S. T., Zaleska-Kociecka, M., Grabowski, M., Dąbrowski, M., Wozniak, S., Piotrowska, K., Banaszewski, M., Imiela, J., Stepinska, J., Pérez, A. González, Ordoñez, P. Florez, Giribet, A., Cuervo, M. A. Alonso, Cuervo, R. Alonso, Esteban, M. A. Rodriguez, Fraile, L. Iglesias, Mittelbrum, C. Ponte, Albaiceta, G. Muñiz, Koeze, J., Keus, F., Dieperink, W., van der Horst, I. C. C., van Meurs, M., Zijlstra, J. G., Roberts, S., Caballero, C. 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E., Sinha, K., Luney, M., Palmer, K., Keating, L., Abu-Habsa, M., Bahl, R., Baskaralingam, N., Ahmad, A., Kanapeckaite, L., Bhatti, P., Glace, S., Jeyabraba, S., Lewis, H. F., Kostopoulos, A., Raja, M., West, A., Ely, A., Turkoglu, L. M., Zolfaghari, P., Baptista, J. P., Marques, M. P., Martins, P., Pimentel, J., Gupta, D., Su, Y. C., Villacres, S., Stone, M. E., Parsikia, A., Medar, S., O’Dea, K. P., Porter, J., Tirlapur, N., Jonathan, J. M., Singh, S., Takata, M., Abu-Habsa, M., Ahmad, A., McWhirter, E., Lyon, R., Hariz, M. L., Azmi, E., Alkhan, J., Honeybul, S., Movsisyan, V., Petrikov, S., Marutyan, Z., Aliev, I., Evdokimov, A., Antonucci, E., Merz, T., Hartmann, C., Pelosi, P., Calzia, E., Radermacher, P., Nußbaum, B., Hartmann, C., Huber-Lang, M., Gröger, M., Radermacher, P., Nußbaum, B., Nußbaum, B., Antonucci, E., Calzia, E., Pelosi, P., Radermacher, P., Hartmann, C., Svoren-Jabalera, E., Davenport, E. E., Humburg, P., Knight, J., Hinds, C. J., Jun, I. J., Kim, W. J., Lee, E. H., Besch, G., Perrotti, A., Puyraveau, M., Carteron, L., Baltres, M., Samain, E., Chocron, S., Pili-Floury, S., Plata-Menchaca, E. P., Sabater-Riera, J., Estruch, M., Boza, E., Sbraga, F., Toscana-Fernández, J., Bruguera-Pellicer, E., Ordoñez-Llanos, J., Pérez-Fernández, X. L., Cavaleiro, P., Tralhão, A., Arrigo, M., Lopes, J.-P., Lebrun, M., Cholley, B., PerezVela, J. L., MarinMateos, H., Rivera, J. J. Jimenez, Llorente, M. A. Alcala, De Marcos, B. Gonzalez, Fernandez, F. J. Gonzalez, Laborda, C. Garcia, Zamora, D. Fernandez, Delgado, J. C. Lopez, Imperiali, C., Berbel-Franco, D., Dastis, M., Moreno-Gonzalez, G., Perez-Sanchez, J., Romera-Peregrina, I., Abellan-Lencina, R., Martinez-Pascual, A., Fuentes-Mila, V., Gonzalez-Romero, M., Górka, J., Górka, K., Iwaniec, T., Frołow, M., Polok, K., Fronczek, J., Kózka, M., Musiał, J., Szczeklik, W., Pérez, A. González, Ordoñez, P. Florez, Giribet, A., Cuervo, M. A. Alonso, Cuervo, R. Alonso, Esteban, M. A. Rodriguez, Fraile, L. Iglesias, Mittelbrum, C. Ponte, Albaiceta, G. Muñiz, Ampatzidou, F., Sileli, M., Kehagioglou, G., Madesis, A., Karaiskos, T., Moursia, C., Maleoglou, H., Leleki, K., Drossos, G., Uz, Z., Ince, Y., Papatella, R., Bulent, E., Guerci, P., Ince, C., De Mol, B., Vicka, V., Gineityte, D., Ringaitiene, D., Norkiene, I., Sipylaite, J., Möller, C., Fleischmann, C., Thomas-Rueddel, D. O., Vlasakov, V., Rochwerg, B., Theurer, P., Gattinoni, L., Reinhart, K., Hartog, C. S., Pérez, A. González, Al Sibai, J. Zanabili, Camblor, P. Martinez, Fernandez, P. Alvarez, Gala, J. M. García, Guisasola, J. Silba, Albaiceta, G. Muñiz, Tamura, T., Yatabe, T., Miyajima, I., Yamashita, K., Yokoyama, M., Ampatzidou, F., Kehagioglou, G., Dalampini, E., Nastou, M., Baddour, A., Ignatiadis, A., Asteri, T., Drossos, G., Hathorn, K. E., Purtle, S. W., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Viana, M. V., Tonietto, T. A., Gross, L. A., Costa, V. L., Tavares, A. L. J., Lisboa, B. O., Moraes, R. B., Vieira, S. R., Viana, L. V., Azevedo, M. J., Ceniccola, G. D., Pequeno, R. S. F., Holanda, T. P., Mendonça, V. S., Araújo, W. M. C., Carvalho, L. S. F., Segaran, E., Vickers, L., Brinchmann, K., Wignall, I., Rubulotta, F., De Brito-Ashurst, I., del Olmo, R., Esteban, M. J., Vaquerizo, C., Carreño, R., Gálvez, V., Kaminsky, G., Nieto, B., Fuentes, M., De la Torre, M. A., Torres, E., Alonso, A., Velayos, C., Saldaña, T., Escribá, A., GRIP, J., Kölegård, R., Sundblad, P., Rooyackers, O., Naser, Ben, Jaziri, F., Jazia, A. Ben, Barghouth, M., Hentati, O., Skouri, W., El Euch, M., Mahfoudhi, M., Turki, S., Abdelghni, K. Ben, Abdallah, Ben, Maha, B. N. M., Cánovas, J., Sotos, F., López, A., Lorente, M., Burruezo, A., Torres, D., Polok, K., Włudarczyk, A., Górka, J., Hałek, A., Musiał, J., Szczeklik, W., Jazia, A. Ben, Jaziri, F., Bargouth, M., Bennasr, M., Turki, S., Abdelghani, K. Ben, Abdallah, T. Ben, de Grooth, H. J., Geenen, I. L., Parienti, J. J., Straaten, H. M. Oudemans-van, Shum, H. P., King, H. S., Chan, K. C., Yan, W. W., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Pedrosa, M. Morales, Gubianas, C. Murcia, Bertolin, C. Fuster, Batllori, N. Vila, Sirvent, J. M., Wykes, K., Jack, J., Morgan, P., Mukhopadhyay, A., Chan, H. Y., Kowitlawakul, Y., Remani, D., Leong, C. S. F., Henry, C. J., Puthucheary, Z. A., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M., Espinoza, E. D. Valenzuela, Welsh, S. P., Motta, M. F., Guerra, E., Zerpa, M. C. l., Zechner, F., Furche, M., Berdaguer, F., Birri, P. N. Rubatto, Risso-Vazquez, A., Dubin, A., Masevicius, F. D., Greaney, D., Magee, A., Fitzpatrick, G., Lugo-Cob, R. G., Sánchez-Hurtado, L. A., Arvizu-Tachiquín, P. C., Tejeda-Huezo, B. C., Cano-Oviedo, A. A., Baltazar-Torres, J. A., Aydogan, M. S., Togal, T., Taha, A., Chai, H. Z., Kam, C., Razali, S. S. Yang, Sivasamy, V., Kuan, L. Y., Poulose, V., Morales, M. A. Lopez, Castro, S., Pires, T., Melão, L., Krystopchuk, A., Pereira, I., Granja, C., Taniguchi, L. U., Pires, E. M. C., Vieira, Jr, J. M., Azevedo, L. C. P., Nurses of the Central and General ICUs of Shiraz Namazi Hospital, Sedation an Delirium Group Hospital Universitari de Bellvitge, SPACeR group (Surrey Peri-operative, Anaesthesia and Critical Care Collaborative Research Group), for the PRoVENT investigators and the PROVE Network, SEMICYUC/GETGAG Working Group, TAVeM study group, POPC-CB investigators, DESIRE (DExmedetomidine for Sepsis in ICU Randomized Evaluation) Trial Investigators, GEMINI, Bioethics work group of SEMICYUC, The FINNAKI Study Group, Queen Square Neuroanaesthesia and Neurocritical Care Resreach Group, Renal Transplantation HUVR, GEMINI, EDISVAL Group, EDISVAL Group, PLUG Working group, TAVeM study Group, The FINNAKI Study Group, on behalf of Department of Professional Development, ESICM, Critical Care Research Group, SIRAKI group, and Grupo ESBAGA

Published
2016
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11. Combined Bacterial Meningitis and Infective Endocarditis: When Should We Search for the Other When Either One is Diagnosed?

Author

Béraud, Guillaume, Tubiana, Sarah, Erpelding, Marie-Line, Le Moing, Vincent, Chirouze, Catherine, Gorenne, Isabelle, Manchon, Pauline, Tattevin, Pierre, Vernet, Veronique, Varon, Emmanuelle, Hoen, Bruno, Duval, Xavier, Obadia, J., Leport, C., Poyart, C., Revest, M., Selton-Suty, C., Strady, C., Vandenesch, F., Bernard, Y., Chocron, S., Plesiat, P., Abouliatim, I., de Place, C., Donnio, P., Alla, F., Carteaux, J., Doco-Lecompte, T., Lion, C., Aissa, N., Baehrel, B., Jaussaud, R., Nazeyrollas, P., Cambau, E., Iung, B., Nataf, P., Chidiac, C., Celard, M., Delahaye, F., Aumaître, H., Frappier, J., Oziol, E., Sotto, A., Sportouch, C., Bouvet, A., Bes, M., Abassade, P., Abrial, E., Acar, C., Alexandra, J., Amireche, N., Amrein, D., Andre, P., Appriou, M., Arnould, M., Atoui, A., Aziza, F., Baille, N., Bajolle, N., Battistella, P., Baumard, S., Ben Ali, A., Bertrand, J., Bialek, S., Bois Grosse, M., Boixados, M., Borlot, F., Bouchachi, A., Bouche, O., Bouchemal, S., Bourdon, J., Brasme, L., Bruntz, J., Cailhol, J., Caplan, M.P., Carette, B., Cartry, O., Cazorla, C., Chamagne, H., Champagne, H., Chanques, G., Chevalier, B., Chometon, F., Christophe, C., Colin de Verdiere, N., Daneluzzi, V., David, L., Danchin, N., de Lentdecker, P., Delcey, V., Deleuze, P., Deroure, B., Descotes-Genon, V., Didier Petit, K., Dinh, A., Doat, V., Duchene, F., Duhoux, F., Dupont, M., Ederhy, S., Epaulard, O., Evest, M., Faucher, J., Fauveau, E., Ferry, T., Fillod, M., Floch, T., Fraisse, T., Frapier, J., Freysz, L., Fumery, B., Gachot, B., Gallien, S., Garcon, P., Gaubert, A., Genoud, J., Ghiglione, S., Godreuil, C., Gandjbakhch, I., Grentzinger, A., Groben, L., Gherissi, D., Hagege, A., Hammoudi, N., Heliot, F., Henry, P., Houriez, P., Hustache-Mathieu, L., Huttin, O., Imbert, S., Jaureguiberry, S., Kaaki, M., Konate, A., Kuhn, J., Kural Menasche, S., Lafitte, A., Lafon, B., Lanternier, F., Le Chenault, V., Lechiche, C., Lefevre Thibaut, S., Lefort, A., Lemoine, J., Lepage, L., Lepousé, C., Leroy, J., Lesprit, P., Letranchant, L., Loncar, G., Lorentz, C., Magnin-Poull, I., Makinson, A., Man, H., Mansouri, M., Marçon, O., Maroni, J., Masse, V., Maurier, F., Mechaï, F., Merceron, O., Messika-Zeitoun, D., Metref, Z., Meyssonnier, V., Mezher, C., Micheli, S., Monsigny, M., Mouly, S., Mourvillier, B., Nallet, O., Nazerollas, P., Noel, V., Payet, B., Pelletier, A., Perez, P., Petit, J., Philippart, F., Piet, E., Plainvert, C., Popovic, B., Porte, J., Pradier, P., Ramadan, R., Richemond, J., Rodermann, M., Roncato, M., Roigt, I., Ruyer, O., Saada, M., Schwartz, J., Simon, M., Simorre, B., Skalli, S., Spatz, F., Sudrial, J., Tartiere, L., Terrier de La Chaize, A., Thiercelin, M., Thomas, D., Thomas, M., Toko, L., Tournoux, F., Tristan, A., Trouillet, J., Tual, L., Verdier, F., Vernet Garnier, V., Vidal, V., Weyne, P., Wolff, M., Wynckel, A., Zannad, N., Zinzius, P., Ploy, M.-C., Caron, F., Bollaert, P.-E., Gaillot, O., Taha, M.-K., Bonacorsi, S., Lecuit, M., Gravet, A., Frachet, B., Debroucker, T., Levy-Bruhl, D., Raffi, F., Preau, M., Anguel, N., Argaud, L., Arista, S., Armand-Lefevre, L., Balavoine, S., Baraduc, R., Barnaud, G., Bernard, L., Bernars, G., Bertei, D., Bessede, E., Billard Pomares, T., Biron, C., Bland, S., Boileau, J., Boubeau, P., Bourdon, S., Bousquet, A., Boyer, S., Bozorg-Grayeli, A., Bret, L., Bretonniere, C., Bricaire, F., Brocas, E., Brun, M., Buret, J., Burucoa, C., Cabalion, J., Cabon, M., Camuset, G., Canevet, C., Carricajo, A., Castan, B., Caumes, E., Cazanave, C., Chabrol, A., Challan-Belval, T., Chanteperdrix-Marillier, V., Chaplain, C., Charlier-Woerther, C., Chaussade, H., Clair, B., Colot, J., Conil, J.-M., Cordel, H., Cormier, P., Cousson, J., Cronier, P., Cua, E., Dao-Dubremetz, A., Dargere, S., Degand, N., Dekeyser, S., Delaune, D., Denes, E., Dequin, P.-F., Descamps, D., Descloux, E., Desmaretz, J.-L., Diehl, J.-L., Dimet, J., Escaut, L., Fabe, C., Faibis, F., Flateau, C., Fonsale, N., Forestier, E., Fortineau, N., Gagneux-Brunon, A., Garandeau, C., Garcia, M., Garot, D., Gaudry, S., Goehringer, F., Gregoire-Faucher, V., Grosset, M., Gubavu, C., Gueit, I., Guelon, D., Guimard, T., Guinard, J., Hadou, T., Helene, J.-P., Henard, S., Henry, B., Hochart, A.-C., Illes, G., Jaffuel, S., Jarrin, I., Jaureguy, F., Joseph, C., Juvin, M.-E., Kayal, S., Kerneis, S., Lacassin, F., Lamaury, I., Lanotte, P., Laurens, E., Laurichesse, H., Le Brun, C., Le Turnier, P., Lecuyer, H., Ledru, S., Legrix, C., Lemaignen, A., Lemble, C., Lemee, L., Lesens, O., Levast, M., Lhommet, C., Males, S., Malpote, E., Martin-Blondel, G., Marx, M., Masson, R., Matray, O., Mbadi, A., Mellon, G., Merens, A., Meyohas, M.-C., Michon, A., Mootien Yoganaden, J., Morquin, D., Mrozek, N., Nguyen, S., Nguyen, Y., Ogielska, M., Page, B., Patrat-Delon, S., Patry, I., Pechinot, A., Picot, S., Pierrejean, D., Piroth, L., Plassart, C., Plessis, P., Portel, L., Poubeau, P., Poupard, M., Prazuck, T., Quaesaet, L., Ramanantsoa, A., Rapp, C., Raskine, L., Raymond, J., Riche, A., Robaday-Voisin, S., Robin, F., Romaszko, J.-P., Rousseau, F., Roux, A.-L., Royer, C., Salmon, D., Saroufim, C., Schmit, J.-L., Sebire, M., Segonds, C., Sivadon-Tardy, V., Soismier, N., Son, O., Sunder, S., Suy, F., Tande, D., Tankovic, J., Valin, N., van Grunderbeeck, N., Verdon, R., Vergnaud, M., Vernet-Garnier, V., Vidal, M., Vitrat, V., Vittecoq, D., Vuotto, F., Laouenan, C., Marcault, E., Mentre, F., Pasquet, B., Roy, C., Centre hospitalier universitaire de Poitiers (CHU Poitiers), Centre d'investigation Clinique [CHU Bichat] - Épidémiologie clinique (CIC 1425), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Centre d'investigation clinique [Nancy] (CIC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Laboratoire Chrono-environnement (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), CHU Pontchaillou [Rennes], ARN régulateurs bactériens et médecine (BRM), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC)-Université Sorbonne Paris Nord, Centre d'investigation clinique - Epidémiologie clinique [Nancy] (CIC-EC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), CHU Montpellier, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Centre Hospitalier Universitaire de Reims (CHU Reims), Centre Hospitalier Intercommunal de Créteil (CHIC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), and The AEPEI IE cohort was funded by a research grant from the French Ministry of Health (PHRC 2007), grants from the Société Française de Cardiologie, the European Society of Clinical Microbiology and Infectious Diseases, and Novartis France. The sponsor was Délégation à la Recherche Clinique et au Développement, Centre Hospitalier Universitaire de Besançon. The COMBAT cohort was funded by Assistance Publique—Hôpitaux de Paris, Inserm, The French Society of Infectious Diseases (SPILF), and Pfizer Laboratory. It was also supported by the Observatoire de la Resistance du Pneumocoque (ORP) and Santé Publique France. The sponsor of the study and the funding sources had no role in study design, data collection, data analysis, data interpretation or writing of the report. The corresponding author had full access to all the data in the study and had final responsibility for the decision to submit it for publication. The Rapid Service Fee was funded by the University Hospital of Poitiers, to which the corresponding author is affiliated.

Subjects
Microbiology (medical), Infectious Diseases, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Echocardiography, Austrian syndrome, Staphylococcus, [SDV]Life Sciences [q-bio], Bacterial meningitis, Streptococcus, Infective endocarditis
Abstract

International audience; Introduction: We aimed to describe patients with coexisting infective endocarditis (IE) and bacterial meningitis (BM).Methods: We merged two large prospective cohorts, an IE cohort and a BM cohort, with only cases of definite IE and community-acquired meningitis. We compared patients who had IE and BM concurrently to patients with IE only and BM only.Results: Among the 1030 included patients, we identified 42 patients with IE-BM (4.1%). Baseline characteristics of patients with IE-BM were mostly similar to those of patients with IE, but meningitis was the predominant presentation at admission (39/42, 92.3%). Causative pathogens were predominantly Streptococcus pneumoniae (18/42, 42.9%) and Staphylococcus aureus (14/42, 33.3%). All pneumococcal IE were associated with BM (18/18). BM due to oral and group D streptococci, Streptococcus agalactiae, and S. aureus were frequently associated with IE (14/30, 46.7%). Three-month mortality was 28.6% in patients with IE-BM, 20.5% in patients with IE, and 16.6% in patients with BM.Conclusions: Patients with pneumococcal IE or altered mental status during IE must be investigated for BM. Patients with S. aureus, oral and group D streptococcal or enterococcal BM, or unfavorable outcome in pneumococcal meningitis would benefit from an echocardiography. Patients with the dual infection have the worst prognosis. Their identification is mandatory to initiate appropriate treatment.

Published
2022

16. Correction to: European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria (Journal of Cardiothoracic Surgery, (2021), 16, 1, (171), 10.1186/s13019-021-01536-5)

Author

Biancari, F., Mariscalco, G., Yusuff, H., Tsang, G., Luthra, S., Onorati, F., Francica, A., Rossetti, C., Perrotti, A., Chocron, S., Fiore, A., Folliguet, T., Pettinari, M., Dell'Aquila, A. M., Demal, T., Conradi, L., Detter, C., Pol, M., Ivak, P., Schlosser, F., Forlani, S., Chetty, G., Harky, A., Kuduvalli, M., Field, M., Vendramin, I., Livi, U., Rinaldi, M., Ferrante, L., Etz, C., Noack, T., Mastrobuoni, S., De Kerchove, L., Jormalainen, M., Laga, S., Meuris, B., Schepens, M., Dean, Z. E., Vento, A., Raivio, P., Borger, M., and Juvonen, T.

Published
2021

22. Extracorporeal Membrane Oxygenation for Patients with Severe COVID-19-Related ARDS: A European Multicenter Analysis

Author

Zipfel, S., additional, Biancari, F., additional, Mariscalco, G., additional, Dalén, M., additional, Settembre, N., additional, Welp, H., additional, Perrotti, A., additional, Wiebe, K., additional, Leo, E., additional, Loforte, A., additional, Chocron, S., additional, Pacini, D., additional, Juvonen, T., additional, Broman, L. M., additional, Di Perna, D., additional, Yusuff, H., additional, Harvey, C., additional, Mongardon, N., additional, Maureira, J. P., additional, Levy, B., additional, Falk, L., additional, Ruggieri, V. G., additional, Kluge, S., additional, Reichenspurner, H., additional, Folliguet, T., additional, and Fiore, A., additional

Published
2021
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23. Neutrophil Gelatinase-Associated Lipocalin Measured on Clinical Laboratory Platforms for the Prediction of Acute Kidney Injury and the Associated Need for Dialysis Therapy: A Systematic Review and Meta-analysis

Author

Albert, C. Zapf, A. Haase, M. Röver, C. Pickering, J.W. Albert, A. Bellomo, R. Breidthardt, T. Camou, F. Chen, Z. Chocron, S. Cruz, D. de Geus, H.R.H. Devarajan, P. Di Somma, S. Doi, K. Endre, Z.H. Garcia-Alvarez, M. Hjortrup, P.B. Hur, M. Karaolanis, G. Kavalci, C. Kim, H. Lentini, P. Liebetrau, C. Lipcsey, M. Mårtensson, J. Müller, C. Nanas, S. Nickolas, T.L. Pipili, C. Ronco, C. Rosa-Diez, G.J. Ralib, A. Soto, K. Braun-Dullaeus, R.C. Heinz, J. Haase-Fielitz, A.

Abstract

Rationale & Objective: The usefulness of measures of neutrophil gelatinase-associated lipocalin (NGAL) in urine or plasma obtained on clinical laboratory platforms for predicting acute kidney injury (AKI) and AKI requiring dialysis (AKI-D) has not been fully evaluated. We sought to quantitatively summarize published data to evaluate the value of urinary and plasma NGAL for kidney risk prediction. Study Design: Literature-based meta-analysis and individual-study-data meta-analysis of diagnostic studies following PRISMA-IPD guidelines. Setting & Study Populations: Studies of adults investigating AKI, severe AKI, and AKI-D in the setting of cardiac surgery, intensive care, or emergency department care using either urinary or plasma NGAL measured on clinical laboratory platforms. Selection Criteria for Studies: PubMed, Web of Science, Cochrane Library, Scopus, and congress abstracts ever published through February 2020 reporting diagnostic test studies of NGAL measured on clinical laboratory platforms to predict AKI. Data Extraction: Individual-study-data meta-analysis was accomplished by giving authors data specifications tailored to their studies and requesting standardized patient-level data analysis. Analytical Approach: Individual-study-data meta-analysis used a bivariate time-to-event model for interval-censored data from which discriminative ability (AUC) was characterized. NGAL cutoff concentrations at 95% sensitivity, 95% specificity, and optimal sensitivity and specificity were also estimated. Models incorporated as confounders the clinical setting and use versus nonuse of urine output as a criterion for AKI. A literature-based meta-analysis was also performed for all published studies including those for which the authors were unable to provide individual-study data analyses. Results: We included 52 observational studies involving 13,040 patients. We analyzed 30 data sets for the individual-study-data meta-analysis. For AKI, severe AKI, and AKI-D, numbers of events were 837, 304, and 103 for analyses of urinary NGAL, respectively; these values were 705, 271, and 178 for analyses of plasma NGAL. Discriminative performance was similar in both meta-analyses. Individual-study-data meta-analysis AUCs for urinary NGAL were 0.75 (95% CI, 0.73-0.76) and 0.80 (95% CI, 0.79-0.81) for severe AKI and AKI-D, respectively; for plasma NGAL, the corresponding AUCs were 0.80 (95% CI, 0.79-0.81) and 0.86 (95% CI, 0.84-0.86). Cutoff concentrations at 95% specificity for urinary NGAL were >580 ng/mL with 27% sensitivity for severe AKI and >589 ng/mL with 24% sensitivity for AKI-D. Corresponding cutoffs for plasma NGAL were >364 ng/mL with 44% sensitivity and >546 ng/mL with 26% sensitivity, respectively. Limitations: Practice variability in initiation of dialysis. Imperfect harmonization of data across studies. Conclusions: Urinary and plasma NGAL concentrations may identify patients at high risk for AKI in clinical research and practice. The cutoff concentrations reported in this study require prospective evaluation. © 2020 National Kidney Foundation, Inc.

Published
2020

25. Transcatheter aortic valve implantation: early results of the FRANCE (FRench Aortic National CoreValve and Edwards) registry

Author

Eltchaninoff, Hélène, Prat, Alain, Gilard, Martine, Leguerrier, Alain, Blanchard, Didier, Fournial, Gérard, Iung, Bernard, Donzeau-Gouge, Patrick, Tribouilloy, Christophe, Debrux, Jean-Louis, Pavie, Alain, Gueret, Pascal, Leprince, P, Beygui, F, Collet, J-P, Himbert, D, Nataf, P, Vahanian, A, Lefevre, T, Romano, M, Eltchaninoff, H, Litzler, P-Y, Bessou, J-P, Cribier, A, Fajadet, J, Carrie, D, Berthoumieu, P, Dumonteil, N, Fournial, G, Teiger, E, Dubois Randé, J-L, Kirsch, M, Blanchard, D, Fabiani, J-N, Sudre, A, Modine, T, Dos Santos, P, Guibaud, J-P, Roques, X, Gilard, M, Boschat, J, Bezon, E, Schiele, F, Chocron, S, Meneveau, N, Bassand, JP, Rioufol, G, Obadia, J-F, Tirouvanziam, A, Roussel, J-C, Crochet, D, Collard, F, Bonnet, J-L, Cuisset, T, Wolf, J-E, Bouchot, O, Gueret, P, Pavie, A, Blanchard, D, Debrux, J-L, Donzeau-Gouge, P, Eltchaninoff, H, Gilard, M, Iung, B, Leguerrier, A, Prat, A, Tribouilloy, C, and Chevreul, K

Published
2011
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27. Simple Scoring System to Predict In‐Hospital Mortality After Surgery for Infective Endocarditis

Author

Gatti, Giuseppe, Perrotti, Andrea, Obadia, Jean-François, Duval, Xavier, Iung, Bernard, Alla, François, Chirouze, Catherine, Selton-Suty, Christine, Hoen, Bruno, Sinagra, Gianfranco, Delahaye, François, Tattevin, Pierre, Le Moing, Vincent, Pappalardo, Aniello, Chocron, Sidney, Hoen, B., Duval, X., Alla, F., Bouvet, A., Briancon, S., Cambau, E., Celard, M., Chirouze, C., Danchin, N., Doco-Lecompte, T., Delahaye, F., Etienne, J., Iung, B., Le Moing, V., Obadia, J. F., Leport, C., Poyart, C., Revest, M., Selton-Suty, C., Strady, C., Tattevin, P., Vandenesch, F., Bernard, Y., Chocron, S., Plesiat, P., Abouliatim, I., De Place, C., Donnio, P. Y., Carteaux, J. P., Lion, C., Aissa, N., Baehrel, B., Jaussaud, R., Nazeyrollas, P., Vernet, V., Nataf, P., Chidiac, C., Aumaître, H., Frappier, J. M., Oziol, E., Sotto, A., Sportouch, C., Bes, M., Abassade, P., Abrial, E., Acar, C., Alexandra, J. F., Amireche, N., Amrein, D., Andre, P., Appriou, M., Arnould, M. A., Assayag, P., Atoui, A., Aziza, F., Baille, N., Bajolle, N., Battistella, P., Baumard, S., Ben Ali, A., Bertrand, J., Bialek, S., Bois Grosse, M., Boixados, M., Borlot, F., Bouchachi, A., Bouche, O., Bouchemal, S., Bourdon, J. L., Brasme, L., Bricaire, F., Brochet, E., Bruntz, J. F., Cady, A., Cailhol, J., Caplan, M. P., Carette, B., Cartry, O., Cazorla, C., Chamagne, H., Champagne, H., Chanques, G., Chastre, J., Chevalier, B., Chometon, F., Christophe, C., Cohen, A., Colin de Verdiere, N., DANELUZZI, VALERIA, David, L., De Lentdecker, P., Delcey, V., Deleuze, P., Donal, E., Deroure, B., Descotes-Genon, V., Didier Petit, K., Dinh, A., Doat, V., Duchene, F., Duhoux, F., Dupont, M., Ederhy, S., Epaulard, O., Evest, M., Faucher, J. F., FANTIN, BARBARA, Fauveau, E., Ferry, T., Fillod, M., Floch, T., Fraisse, T., Frapier, J. M., Freysz, L., Fumery, B., Gachot, B., Gallien, S., Gandjbach, I., Garcon, P., Gaubert, A., Genoud, J. L., Ghiglione, S., Godreuil, C., Grentzinger, A., Groben, L., Gherissi, D., Guéret, P., Hagege, A., Hammoudi, N., Heliot, F., Henry, P., Herson, S., Houriez, P., Hustache-Mathieu, L., Huttin, O., Imbert, S., Jaureguiberry, S., Kaaki, M., Konate, A., Kuhn, J. M., Kural Menasche, S., Lafitte, A., Lafon, B., Lanternier, F., Le Chenault, V., Lechiche, C., Lefèvre-Thibaut, S., Lefort, A., Leguerrier, A., Lemoine, J., Lepage, L., Lepouse', C., Leroy, J., Lesprit, P., Letranchant, L., Loisance, D., Loncar, G., Lorentz, C., Mabo, P., Magnin-Poull, I., May, T., Makinson, A., Man, H., Mansouri, M., Marxcon, O., Maroni, J. P., Masse, V., Maurier, F., Meyohas, M. C., Michel, P. L., Michelet, C., Mechaï, F., Merceron, O., Messika-Zeitoun, D., Metref, Z., Meyssonnier, V., Mezher, C., Micheli, S., Monsigny, M., Mouly, S., Mourvillier, B., Nallet, O., Noel, V., Papo, T., Payet, B., Pelletier, A., Perez, P., Petit, J. S., Philippart, F., Piet, E., Plainvert, C., Popovic, B., Porte, J. M., Pradier, P., Ramadan, R., Richemond, J., Rodermann, M., Roncato, M., Roigt, I., Ruyer, O., Saada, M., Schwartz, J., Simon, M., Simorre, B., Skalli, S., Spatz, F., Sudrial, J., Tartiere, L., Terrier De La Chaise, A., Thiercelin, M. C., Thomas, D., Thomas, M., Toko, L., Tournoux, F., Tristan, A., Trouillet, J. L., Tual, L., Vahanian, A., Verdier, F., Vernet Garnier, V., vidal, valentina, Weyne, P., Wolff, M., Wynckel, A., Zannad, N., Zinzius, P. Y., University hospital of Trieste, Marqueurs pronostiques et facteurs de régulations des pathologies cardiaques et vasculaires - UFC ( UR 3920) (PCVP / CARDIO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Hôpital Louis Pradel [CHU - HCL], Hospices Civils de Lyon (HCL), Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), CIC Bichat (CIC1425), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM), DHU FIRE Centre de compétence des maladies pulmonaires rares, Service de cardiologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Maladies chroniques, santé perçue, et processus d'adaptation (APEMAC), Université de Lorraine (UL), Service des maladies infectieuses et tropicales, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy], Service de Cardiologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service des Maladies Infectieuses et Tropicales [Point-à-Pitre, Guadeloupe], CHU Pointe-à-Pitre/Abymes [Guadeloupe], Service des maladies infectieuses et réanimation médicale [Rennes] = Infectious Disease and Intensive Care [Rennes], CHU Pontchaillou [Rennes], Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques et émergentes (TransVIHMI), Institut de Recherche pour le Développement (IRD)-Université de Yaoundé I-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Dr Duval reports grants from Pfizer Inc (New York, NY) outside the submitted work, Association for the Study and Prevention of Infective Endocarditis Study Group–Association pour l’ Etude et la Prevention de l’Endocadite Infectieuse, Modèles et méthodes de l'évaluation thérapeutique des maladies chroniques (U738 / UMR_S738), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot - Paris 7 (UPD7)-AP-HP - Hôpital Bichat - Claude Bernard [Paris]-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Département de Santé Publique [Paris], Institut de recherche en santé publique [Paris], Laboratoire Chrono-environnement - UFC (UMR 6249) (LCE), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)-Hôpital Saint-Jacques, Centre Michel de Boüard - Centre de recherches archéologiques et historiques anciennes et médiévales (CRAHAM), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS), Recherches Translationnelles sur le VIH et les maladies infectieuses (TransVIHMI), Université Montpellier 1 (UM1)-Institut de Recherche pour le Développement (IRD)-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Universtié Yaoundé 1 [Cameroun]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Marqueurs pronostiques et facteurs de régulations des pathologies cardiaques et vasculaires - UFC ( EA 3920) (PCVP / CARDIO), Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)-Université de Franche-Comté (UFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)-Hôpital Jean Minjoz, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Recherche pour le Développement (IRD)-Université Montpellier 1 (UM1)-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Universtié Yaoundé 1 [Cameroun]-Université de Montpellier (UM), Centre d'Investigation Clinique Antilles Guyane, Inserm CIC1424, Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques er émergentes (TransVIHMI), Modèles et méthodes de l'évaluation thérapeutique des maladies chroniques, Gatti, Giuseppe, Perrotti, Andrea, Obadia, Jean-Françoi, Duval, Xavier, Iung, Bernard, Alla, Françoi, Chirouze, Catherine, Selton-Suty, Christine, Hoen, Bruno, Sinagra, Gianfranco, Delahaye, Françoi, Tattevin, Pierre, Le Moing, Vincent, Pappalardo, Aniello, Chocron, Sidney, Hoen, B., Duval, X., Alla, F., Bouvet, A., Briancon, S., Cambau, E., Celard, M., Chirouze, C., Danchin, N., Doco-Lecompte, T., Delahaye, F., Etienne, J., Iung, B., Le Moing, V., Obadia, J. F., Leport, C., Poyart, C., Revest, M., Selton-Suty, C., Strady, C., Tattevin, P., Vandenesch, F., Bernard, Y., Chocron, S., Plesiat, P., Abouliatim, I., De Place, C., Donnio, P. Y., Carteaux, J. P., Lion, C., Aissa, N., Baehrel, B., Jaussaud, R., Nazeyrollas, P., Vernet, V., Nataf, P., Chidiac, C., Aumaître, H., Frappier, J. M., Oziol, E., Sotto, A., Sportouch, C., Bes, M., Abassade, P., Abrial, E., Acar, C., Alexandra, J. F., Amireche, N., Amrein, D., Andre, P., Appriou, M., Arnould, M. A., Assayag, P., Atoui, A., Aziza, F., Baille, N., Bajolle, N., Battistella, P., Baumard, S., Ben Ali, A., Bertrand, J., Bialek, S., Bois Grosse, M., Boixados, M., Borlot, F., Bouchachi, A., Bouche, O., Bouchemal, S., Bourdon, J. L., Brasme, L., Bricaire, F., Brochet, E., Bruntz, J. F., Cady, A., Cailhol, J., Caplan, M. P., Carette, B., Cartry, O., Cazorla, C., Chamagne, H., Champagne, H., Chanques, G., Chastre, J., Chevalier, B., Chometon, F., Christophe, C., Cohen, A., Colin de Verdiere, N., Daneluzzi, Valeria, David, L., De Lentdecker, P., Delcey, V., Deleuze, P., Donal, E., Deroure, B., Descotes-Genon, V., Didier Petit, K., Dinh, A., Doat, V., Duchene, F., Duhoux, F., Dupont, M., Ederhy, S., Epaulard, O., Evest, M., Faucher, J. F., Fantin, Barbara, Fauveau, E., Ferry, T., Fillod, M., Floch, T., Fraisse, T., Frapier, J. M., Freysz, L., Fumery, B., Gachot, B., Gallien, S., Gandjbach, I., Garcon, P., Gaubert, A., Genoud, J. L., Ghiglione, S., Godreuil, C., Grentzinger, A., Groben, L., Gherissi, D., Guéret, P., Hagege, A., Hammoudi, N., Heliot, F., Henry, P., Herson, S., Houriez, P., Hustache-Mathieu, L., Huttin, O., Imbert, S., Jaureguiberry, S., Kaaki, M., Konate, A., Kuhn, J. M., Kural Menasche, S., Lafitte, A., Lafon, B., Lanternier, F., Le Chenault, V., Lechiche, C., Lefèvre-Thibaut, S., Lefort, A., Leguerrier, A., Lemoine, J., Lepage, L., Lepouse', C., Leroy, J., Lesprit, P., Letranchant, L., Loisance, D., Loncar, G., Lorentz, C., Mabo, P., Magnin-Poull, I., May, T., Makinson, A., Man, H., Mansouri, M., Marxcon, O., Maroni, J. P., Masse, V., Maurier, F., Meyohas, M. C., Michel, P. L., Michelet, C., Mechaï, F., Merceron, O., Messika-Zeitoun, D., Metref, Z., Meyssonnier, V., Mezher, C., Micheli, S., Monsigny, M., Mouly, S., Mourvillier, B., Nallet, O., Noel, V., Papo, T., Payet, B., Pelletier, A., Perez, P., Petit, J. S., Philippart, F., Piet, E., Plainvert, C., Popovic, B., Porte, J. M., Pradier, P., Ramadan, R., Richemond, J., Rodermann, M., Roncato, M., Roigt, I., Ruyer, O., Saada, M., Schwartz, J., Simon, M., Simorre, B., Skalli, S., Spatz, F., Sudrial, J., Tartiere, L., Terrier De La Chaise, A., Thiercelin, M. C., Thomas, D., Thomas, M., Toko, L., Tournoux, F., Tristan, A., Trouillet, J. L., Tual, L., Vahanian, A., Verdier, F., Vernet Garnier, V., Vidal, Valentina, Weyne, P., Wolff, M., Wynckel, A., Zannad, N., Zinzius, P. Y., Marqueurs pronostiques et facteurs de régulations des pathologies cardiaques et vasculaires - UFC ( PCVP / CARDIO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Hospices Civils de Lyon ( HCL ), Infection, Antimicrobiens, Modélisation, Evolution ( IAME ), Université Paris Diderot - Paris 7 ( UPD7 ) -Université Paris 13 ( UP13 ) -Université Sorbonne Paris Cité ( USPC ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), CIC Bichat ( CIC1425 ), Assistance publique - Hôpitaux de Paris (AP-HP)-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Assistance publique - Hôpitaux de Paris (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Risques, maladies chroniques et société : des systèmes biologiques aux populations, Université Henri Poincaré - Nancy 1 ( UHP ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Hôpital Jean Minjoz, Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy ), Recherches Translationnelles sur le VIH et les maladies infectieuses ( TransVIHMI ), Université Montpellier 1 ( UM1 ) -Université Cheikh Anta Diop ( UCAD ) -Universtié Yaoundé 1 (Cameroun)-Université de Montpellier ( UM ), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), and Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Institut de Recherche pour le Développement (IRD)-Université de Yaoundé I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Université Montpellier 1 (UM1)

Subjects
Male, Time Factors, [SDV]Life Sciences [q-bio], Infective endocarditi, 030204 cardiovascular system & hematology, Logistic regression, 0302 clinical medicine, Risk Factors, pulmonary hypertension, Odds Ratio, Cardiac valvular surgery, Hospital Mortality, Prospective Studies, 030212 general & internal medicine, Treatment outcome, ComputingMilieux_MISCELLANEOUS, Original Research, Cardiovascular Surgery, Framingham Risk Score, Endocarditis, [ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie, Middle Aged, Critical care, Infective endocarditis, Mortality, Predictors, Pulmonary hypertension, Quality control, Cardiology and Cardiovascular Medicine, Cardiac surgery, Europe, Treatment Outcome, Area Under Curve, Female, Mortality/Survival, medicine.medical_specialty, Renal function, Risk Assessment, Decision Support Techniques, 03 medical and health sciences, Predictive Value of Tests, medicine, Humans, Infectious Endocarditis, quality control, Cardiac Surgical Procedures, Risk factor, Aged, Chi-Square Distribution, Receiver operating characteristic, infective endocarditis, business.industry, Odds ratio, cardiac valvular surgery, medicine.disease, mortality, Surgery, critical care, predictors, Logistic Models, ROC Curve, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Valvular Heart Disease, Multivariate Analysis, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business, Predictor
Abstract

Background Aspecific scoring systems are used to predict the risk of death postsurgery in patients with infective endocarditis ( IE ). The purpose of the present study was both to analyze the risk factors for in‐hospital death, which complicates surgery for IE , and to create a mortality risk score based on the results of this analysis. Methods and Results Outcomes of 361 consecutive patients (mean age, 59.1±15.4 years) who had undergone surgery for IE in 8 European centers of cardiac surgery were recorded prospectively, and a risk factor analysis (multivariable logistic regression) for in‐hospital death was performed. The discriminatory power of a new predictive scoring system was assessed with the receiver operating characteristic curve analysis. Score validation procedures were carried out. Fifty‐six (15.5%) patients died postsurgery. BMI >27 kg/m 2 (odds ratio [ OR ], 1.79; P =0.049), estimated glomerular filtration rate OR , 3.52; P IV ( OR , 2.11; P =0.024), systolic pulmonary artery pressure >55 mm Hg ( OR , 1.78; P =0.032), and critical state ( OR , 2.37; P =0.017) were independent predictors of in‐hospital death. A scoring system was devised to predict in‐hospital death postsurgery for IE (area under the receiver operating characteristic curve, 0.780; 95% CI, 0.734–0.822). The score performed better than 5 of 6 scoring systems for in‐hospital death after cardiac surgery that were considered. Conclusions A simple scoring system based on risk factors for in‐hospital death was specifically created to predict mortality risk postsurgery in patients with IE .

Published
2017

29. Dynamic testing of old and young baboon cortical bone with numerical validation

Author

Bredbenner T., Nicholls A.E., Nicolella D., Chocron S., and Havill L.

Subjects
Physics, QC1-999
Abstract

Cortical bone tensile mechanical properties at quasistatic and high rates (∼300s−1) were determined ex vivo using the right femurs of 12 female baboons, (Papio hamadryas spp.) from the Texas Biomedical Research Institute/Southwest National Primate Research Center in San Antonio, Texas. The animals were divided into two age groups: a young age group (6.63 ± 0.6 years) and an old age group (26.96 ± 1.3 years). Seven specimens per group were monotonically loaded to failure to determine their mechanical properties. The quasistatic strength of the bone for the old group was just a little (but not significantly) lower than the young group. High strain rate tests performed with the Hopkinson bar indicate that baboon bone from the older group was significantly weaker under impact loads than that from the younger group. This observation is particularly important due to the similarities between baboon and human bone tissue. Typical strain rates for these tests ranged from 130s−1 to 250s−1. A full-size 3-D simulation of the Hopkinson bar test was performed to confirm that the bone specimen was under stress equilibrium and to evaluate the consistency of the modulus and strength inferred from the tests. Simulations were performed in which the modulus, strength and failure strain were varied to see the sensitivity of the results. Additionally, simplified simulations were performed to estimate the strain rate environment of a femur during a fall at an impact velocity of 5 m/s, similar to a free fall velocity from a height of 1.3 meters. The simulations confirm that strain rates obtained in the Hopkinson bar are relevant because they are similar to those expected inr such a fall.

Published
2012
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31. Comparative Analysis of Prothrombin Complex Concentrate and Fresh Frozen Plasma in the Management of Perioperative Bleeding after Coronary Artery Bypass Grafting

Author

Salsano, A., Mariscalco, G., Santini, F., Ruggieri, V. G., Perrotti, A., Chocron, S., Gherli, R., Reichart, D., Demal, T., Faggian, G., Franzese, I., Dalén, M., Santarpino, G., Fischlein, T., Rubino, A. S., Maselli, D., Nardella, S., Nicolini, F., Saccocci, M., Gatti, G., Bounader, K., Rosato, S., Kinnunen, E., De Feo, M., Tauriainen, T., Onorati, F., and Biancari, F.

Published
2018

32. Utility of glycated hemoglobin screening in patients undergoing elective coronary artery surgery:prospective, cohort study from the E-CABG registry

Author

Nicolini, F. (Francesco), Santarpino, G. (Giuseppe), Gatti, G. (Giuseppe), Reichart, D. (Daniel), Onorati, F. (Francesco), Faggian, G. (Giuseppe), Dalén, M. (Magnus), Khodabandeh, S. (Sorosh), Fischlein, T. (Theodor), Maselli, D. (Daniele), Nardella, S. (Saverio), Rubino, A. S. (Antonino S.), De Feo, M. (Marisa), Salsano, A. (Antonio), Gherli, R. (Riccardo), Mariscalco, G. (Giovanni), Kinnunen, E.-M. (Eeva-Maija), Ruggieri, V. G. (Vito G.), Bounader, K. (Karl), Saccocci, M. (Matteo), Chocron, S. (Sidney), Airaksinen, J. (Juhani), Perrotti, A. (Andrea), and Biancari, F. (Fausto)

Subjects
HbA1c, diabetes, CABG, coronary artery bypass, glycated hemoglobin
Abstract

Background: Patients with increased glycated hemoglobin (HbA1c) seem to be at increased risk of sternal wound infection (SWI) after coronary artery bypass grafting (CABG). However, it is unclear whether increased baseline HbA1c levels may affect other postoperative outcomes. Material and methods: Data on preoperative levels of HbA1c were collected from 2606 patients undergoing elective isolated CABG from 2015 to 2016 and included in the prospective, multicenter E-CABG registry. Results: The prevalence of HbA1c ≥ 53 mmol/mol (7.0%) among non-diabetics was 5.3%, among non-insulin dependent diabetics was 53.5% and among insulin dependent diabetics was 67.1% (p 75 mmol/mol (9.0%) among non-diabetics was 0.5%, among non-insulin dependent diabetics was 5.8% and among insulin dependent diabetics was 10.6% (p

Published
2018

33. Value of Screening Asymptomatic Carotid Artery Stenosis Prior to Coronary Artery Bypass Grafting: Analysis of the E-CABG Registry

Author

Salsano, A., Santarpino, G., Santini, F., Nicolini, F., De Feo, M., Dalén, M., Fischlein, T., Perrotti, A., Reichart, D., Gatti, G., Onorati, F., Franzese, I., Faggian, G., Bancone, C., Chocron, S., Khodabandeh, S., Rubino, A. S., Maselli, D., Nardella, S., Gherli, R., Zanobini, M., Saccocci, M., Bounader, K., Rosato, S., Tauriainen, T., Mariscalco, G., Airaksinen, J., Ruggieri, V. G., and Biancari, F.

Published
2018

34. Chemical interactions between Saturn’s atmosphere and its rings

Author

Waite, J. H., primary, Perryman, R. S., additional, Perry, M. E., additional, Miller, K. E., additional, Bell, J., additional, Cravens, T. E., additional, Glein, C. R., additional, Grimes, J., additional, Hedman, M., additional, Cuzzi, J., additional, Brockwell, T., additional, Teolis, B., additional, Moore, L., additional, Mitchell, D. G., additional, Persoon, A., additional, Kurth, W. S., additional, Wahlund, J.-E., additional, Morooka, M., additional, Hadid, L. Z., additional, Chocron, S., additional, Walker, J., additional, Nagy, A., additional, Yelle, R., additional, Ledvina, S., additional, Johnson, R., additional, Tseng, W., additional, Tucker, O. J., additional, and Ip, W.-H., additional

Published
2018
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35. Novel mutations associated with nephrogenic diabetes insipidus. A clinical-genetic study

Author

García Castaño, A., Pérez de Nanclares, G., Madariaga, L., Aguirre, M., Chocron, S., Madrid, A., Lafita Tejedor, F.J., Gil Campos, M., Sánchez del Pozo, J., Ruiz Cano, R., Espino, M., Gomez Vida, J.M., Santos, F., García Nieto, V.M., Loza, R., Rodríguez, L.M., Hidalgo Barquero, E., Printza, N., Camacho, J.A., Castaño, L., Ariceta, G., and RenalTube Group

Subjects
Male, desmopressin, vomiting, glomerulus filtration rate, frameshift mutation, genetic association, argipressin receptor, DNA Mutational Analysis, nonsense mutation, Diabetes Insipidus, Nephrogenic, genetic analysis, Gene mutation, preschool child, Gastroenterology, polydipsia, newborn, aquaporin 2, Medicine, genetics, gene mutation, Child, Desmopressin, sodium, clinical article, hypernatremia, pedigree, clinical trial, genetic screening, Pedigree, unclassified drug, female, argipressin receptor 2, priority journal, Child, Preschool, Failure to thrive, Female, medicine.symptom, Polydipsia, medicine.drug, medicine.medical_specialty, AQP2 protein, human, failure to thrive, DNA flanking region, Article, nephrogenic diabetes insipidus, Polyuria, Internal medicine, Genetic predisposition, Humans, cyclic AMP, Genetic Predisposition to Disease, human, Genetic Testing, purl.org/pe-repo/ocde/ford#3.02.03 [https], cyclic AMP dependent protein kinase, Aquaporin 2, business.industry, missense mutation, Infant, Newborn, Infant, dehydration, DNA, school child, Nephrogenic diabetes insipidus, medicine.disease, heterozygote, plasma osmolality, multicenter study, Endocrinology, Mutation, Pediatrics, Perinatology and Child Health, polyuria, Hypernatremia, homozygosity, business, genetic predisposition, metabolism
Abstract

Molecular diagnosis is a useful diagnostic tool in primary nephrogenic diabetes insipidus (NDI), an inherited disease characterized by renal inability to concentrate urine. The AVPR2 and AQP2 genes were screened for mutations in a cohort of 25 patients with clinical diagnosis of NDI. Patients presented with dehydration, polyuria-polydipsia, failure to thrive (mean ± SD; Z-height -1.9 ± 2.1 and Z-weight -2.4 ± 1.7), severe hypernatremia (mean ± SD; Na 150 ± 10 mEq/L), increased plasma osmolality (mean ± SD; 311 ± 18 mOsm/Kg), but normal glomerular filtration rate. Genetic diagnosis revealed that 24 male patients were hemizygous for 17 different putative disease-causing mutations in the AVPR2 gene (each one in a different family). Of those, nine had not been previously reported, and eight were recurrent. Moreover, we found those same AVPR2 changes in 12 relatives who were heterozygous carriers. Further, in one female patient, AVPR2 gene study turned out to be negative and she was found to be homozygous for the novel AQP2 p.Ala86Val alteration.Genetic analysis presumably confirmed the diagnosis of nephrogenic diabetes insipidus in every patient of the studied cohort. We emphasize that we detected a high presence (50 %) of heterozygous females with clinical NDI symptoms.• In most cases (90 %), inherited nephrogenic diabetes insipidus (NDI) is an X-linked disease, caused by mutations in the AVPR2 gene. • In rare occasions (10 %), it is caused by mutations in the AQP2 gene. What is new: • In this study, we report 10 novel mutations associated with NDI. • We have detected a high presence (50 %) of heterozygous carriers with clinical NDI symptoms.

Published
2015

36. Intracerebral hemorrhage in ICU: is it worth treating?

Author

Sivakumar, S, Taccone, F, Desai, K, Lazaridis, C, Skarzynski, M, Sekhon, M, Henderson, W, Griesdale, D, Chapple, L, Deane, A, Williams, L, Strickland, R, Lange, K, Heyland, D, Chapman, M, Rowland, M, Garry, P, Westbrook, J, Corkill, R, Antoniades, C, Pattinson, K, Fatania, G, Strong, A, Myers, R, Jermaine, C, Robertson, C, Rusin, C, Hofmeijer, J, Sondag, L, Tjepkema Cloostermans, M, Beishuizen, A, Bosch, F, van Putten, M, Carteron, L, Patet, C, Solari, D, Oddo, M, Ali, M, Dias, C, Almeida, R, Vaz Ferreira, A, Silva, J, Monteiro, E, Cerejo, A, Rocha, A, Elsayed, A, Abougabal, A, Beshey, B, Alzahaby, K, Pozzebon, S, Ortiz, A, Cristallini, S, Lheureux, O, Brasseur, A, Vincent, J, Creteur, J, Hravnak, M, Yousef, K, Chang, Y, Crago, E, Friedlander, R, Abdelmonem, S, Tahon, S, Helmy, T, Meligy, H, Puig, F, Dunn Siegrist, I, Pugin, J, Gupta, S, Govil, D, Srinivasan, S, Patel, S, N, J, Gupta, A, Tomar, D, Shafi, M, Harne, R, Arora, D, Talwar, N, Mazumdar, S, Papakrivou, E, Makris, D, Manoulakas, E, Tsolaki, B, Karadodas, B, Zakynthinos, E, Garcia, I, Martin, A, Encinares, V, Ibañez, M, Montero, J, Labrador, G, Cangueiro, T, Poulose, V, Koh, J, Kam, J, Yeter, H, Kara, A, Aktepe, O, Topeli, A, Tsolakoglou, I, Intas, G, Stergiannis, P, Kolaros, A, Chalari, E, Athanasiadou, E, Martika, A, Fildisis, G, Faivre, V, Mengelle, C, Favier, B, Payen, D, Poppe, A, Winkler, M, Mudersbach, E, Schreiber, J, Wruck, M, Schwedhelm, E, Kluge, S, Zöllner, C, Tavladaki, T, Spanaki, A, Dimitriou, H, Kondili, E, Choulaki, C, Meleti, E, Kafetzopoulos, D, Georgopoulos, D, Briassoulis, G, la Torre, A, de la Torre Prados, M, Tsvetanova Spasova, T, Nuevo Ortega, P, Rueda Molina, C, Fernández Porcel, A, Camara Sola, E, Salido Díaz, L, García Alcántara, A, Meleti, D, Suberviola, B, Riera, J, Rellan, L, Sanchez, M, Robles, J, Lopez, E, Vicente, R, Miñambres, E, Santibañez, M, Le Guen, M, Moore, J, Mason, N, Windpassinger, M, Plattner, O, Mascha, E, Sessler, D, Research, O, Melia, U, Fontanet, J, van den Berg, J, Struys, M, Vereecke, H, Jensen, E, Rood, P, van de Schoor, F, van Tertholen, K, Pickkers, P, van den Boogaard, M, Beardow, Z, Redhead, H, Paramasivam, K, Numan, T, Kamper, A, Peelen, L, Zeman, P, Slooter, A, van Ewijk, C, Jacobs, G, Girbes, A, Myatra, S, Harish, M, Prabu, N, Siddiqui, S, Kulkarni, A, Divatia, J, Murbach, L, Leite, M, Osaku, E, Costa, C, Pelenz, M, Neitzke, N, Moraes, M, Jaskowiak, J, Silva, M, Zaponi, R, Abentroth, L, Ogasawara, S, Jorge, A, Duarte, P, Hernández Sánchez, N, Sánchez Hurtado, L, García Guillen, F, Ñamendys Silva, S, Maghsoudi, B, Emami, M, Khosravi, M, Zand, F, Tabatabaie, H, Masjedi, M, Sabetiyan, G, Mokri, A, Troubleyn, J, Diltoer, M, Jacobs, R, Nguyen, D, De Waele, E, De Regt, J, Honoré, P, Van Gorp, V, Spapen, H, Contreras, R, Toapanta, N, Moreno, G, Sabater, J, Torrado, H, Gonzalez, M, Marin, M, Farigola, E, Gonzalez, A, Fernandez, J, Vera, A, Gisbert, X, Juliá, C, Uya, J, Corral, L, Elias Jones, I, Gemmell, L, Mackay, A, Randall, D, Adwaney, A, Blunden, M, Prowle, J, Kirwan, C, Thomas, N, Owen, H, Darwin, L, Conway, D, Atkinson, D, Sharman, M, Barbanti, C, Amour, J, Gaudard, P, Rozec, B, Mauriat, P, M'Rini, M, Leger, P, Cambonie, G, Liet, J, Girard, C, Laroche, S, Damas, P, Assaf, Z, Loron, G, Lecourt, L, Pouard, P, Kim, S, Na, S, Kim, J, Oh, S, Jung, C, Yoo, S, Min, S, Chung, E, Lee, H, Lee, N, Lee, K, Suh, K, Ryu, H, Marshall, D, Goodson, R, Salciccioli, J, Shalhoub, J, Potter, E, Kirk Bayley, J, Karanjia, N, Forni, L, Creagh Brown, B, Bossy, M, Nyman, M, Tailor, A, D'Antini, D, Spadaro, S, Valentino, F, Sollitto, F, Cinnella, G, Mirabella, L, Calvo, F, Bejarano, N, Padilla, D, Baladron, V, Villajero, P, Villazala, R, Redondo, J, Yuste, A, Liu, J, Shen, F, Teboul, J, Anguel, N, Beurton, A, Bezaz, N, Richard, C, Monnet, X, Fossali, T, Colombo, R, Ottolina, D, Rossetti, M, Mazzucco, C, Marchi, A, Porta, A, Catena, E, Tollisen, K, Andersen, G, Heyerdahl, F, Jacobsen, D, de Waard, M, van IJzendoorn, M, Buter, H, Kingma, W, Navis, G, Boerma, E, Rulisek, J, Balik, M, Zacharov, S, Kim, H, Jeon, S, Namgung, H, Lee, E, Cho, Y, Lee, Y, Huang, A, Cioccari, L, Luethi, N, Mårtensson, J, Bellomo, R, Forsberg, M, Edman, G, Höjer, J, Forsberg, S, Freile, M, Hidalgo, F, Molina, J, Lecumberri, R, Rosselló, A, Travieso, P, Leon, G, Sanchez, J, Frias, L, Rosello, D, Verdejo, J, Serrano, J, Winterwerp, D, van Galen, T, Vazin, A, Karimzade, I, Zand, A, Ozen, E, Ekemen, S, Akcan, A, Sen, E, Yelken, B, Kureshi, N, Fenerty, L, Thibault Halman, G, Erdogan, M, Walling, S, Green, R, Clarke, D, Briassoulis, P, Kalimeris, K, Ntzouvani, A, Nomikos, T, Papaparaskeva, K, Politi, E, Kostopanagiotou, G, Crewdson, K, Rehn, M, Weaver, A, Brohi, K, Lockey, D, Wright, S, Thomas, K, Baker, C, Mansfield, L, Stafford, V, Wade, C, Watson, G, Bryant, A, Chadwick, T, Shen, J, Wilkinson, J, Furneval, J, Henderson, A, Hugill, K, Howard, P, Roy, A, Bonner, S, Baudouin, S, Ramírez, C, Escalada, S, Viera, M, Santana, M, Balcázar, L, Monroy, N, Campelo, F, Vázquez, C, Santana, P, Santana, S, Quintard, H, Bouzat, P, Wollersheim, T, Malleike, J, Haas, K, Carbon, N, Schneider, J, Birchmeier, C, Fielitz, J, Spuler, S, Weber Carstens, S, Enseñat, L, Pérez Madrigal, A, Saludes, P, Proença, L, Gruartmoner, G, Espinal, C, Mesquida, J, Huber, W, Eckmann, M, Elkmann, F, Gruber, A, Lahmer, T, Mayr, U, Herner, A, Schellnegger, R, Schmid, R, Ayoub, W, Samy, W, Esmat, A, Battah, A, Mukhtar, S, Mongkolpun, W, Cortés, D, Cordeiro, C, Funcke, S, Groesdonk, H, Saugel, B, Wagenpfeil, G, Wagenpfeil, S, Reuter, D, Fernandez, M, Fernandez, R, Magret, M, González Castro, A, Bouza, M, García, C, Balerdi, B, Mas, A, Arauzo, V, Añón, J, Ruiz, F, Ferreres, J, Tomás, R, Alabert, M, Tizón, A, Altaba, S, Llamas, N, Goligher, E, Fan, E, Herridge, M, Vorona, S, Sklar, M, Dres, M, Rittayamai, N, Lanys, A, Urrea, C, Tomlinson, G, Reid, W, Rubenfeld, G, Kavanagh, B, Brochard, L, Ferguson, N, Neto, A, de Abreu, M, Pelosi, P, Schultz, M, Guérin, C, Papazian, L, Reignier, J, Ayzac, L, Loundou, A, Forel, J, Rolland Debord, C, Bureau, C, Poitou, T, Clavel, M, Perbet, S, Terzi, N, Kouatchet, A, Similowski, T, Demoule, A, Hunfeld, N, Trogrlic, Z, Ladage, S, Osse, R, Koch, B, Rietdijk, W, Devlin, J, van der Jagt, M, Picetti, E, Ceccarelli, P, Mensi, F, Malchiodi, L, Risolo, S, Rossi, I, Antonini, M, Servadei, F, Caspani, M, Roquilly, A, Lasocki, S, Seguin, P, Geeraerts, T, Perrigault, P, Dahyot Fizelier, C, Paugam Burtz, C, Cook, F, Cinotti, R, Dit Latte, D, Mahe, P, Fortuit, C, Feuillet, F, Asehnoune, K, Marzorati, C, Spina, S, Scaravilli, V, Vargiolu, A, Riva, M, Barbadillo, S, de Molina, F, Álvarez Lerma, F, Rodríguez, A, Zakharkina, T, Martin Loeches, I, Matamoros, S, Povoa, P, Torres, A, Kastelijn, J, Hofstra, J, de Jong, M, Sterk, P, Artigas, A, Bos, L, Moreau, A, Salluh, J, Rodriguez, A, Nseir, S, de Jong, E, van Oers, J, Nijsten, M, de Lange, D, Bonvicini, D, Labate, D, Benacchio, L, Olivieri, A, Pizzirani, E, Lopez Delgado, J, Gonzalez Romero, M, Fuentes Mila, V, Berbel Franco, D, Romera Peregrina, I, Martinez Pascual, A, Perez Sanchez, J, Abellan Lencina, R, Ávila Espinoza, R, Moreno Gonzalez, G, Sbraga, F, Griffiths, S, Grocott, M, Doyle, J, Wilkerson, P, Soon, Y, Huddart, S, Dickinson, M, Riga, A, Zuleika, A, Miyamoto, K, Kawazoe, Y, Morimoto, T, Yamamoto, T, Fuke, A, Hashimoto, A, Koami, H, Beppu, S, Katayama, Y, Ito, M, Ohta, Y, Yamamura, H, Rygård, S, Holst, L, Wetterslev, J, Johansson, P, Perner, A, Soliman, I, van Dijk, D, van Delden, J, Cremer, O, Mcwilliams, D, Snelson, C, Neves, A, Loudet, C, Busico, M, Vazquez, D, Villalba, D, Veronesi, M, Lischinsky, A, López, F, Mori, L, Plotnikow, G, Díaz, A, Giannasi, S, Hernandez, R, Krzisnik, L, Cecotti, C, Viola, L, Lopez, R, Sottile, J, Benavent, G, Estenssoro, E, Chen, C, Lai, C, Cheng, K, Chou, W, Chan, K, Roeker, L, Horkan, C, Gibbons, F, Christopher, K, Weijs, P, Mogensen, K, Rawn, J, Robinson, M, Tang, Z, Qiu, C, Ouyang, B, Cai, C, Guan, X, Regueira, T, Cea, L, Carlos, S, Elisa, B, Puebla, C, Vargas, A, Poulsen, M, Thomsen, L, Kjærgaard, S, Rees, S, Karbing, D, Frank, S, Müller, M, Skrypnikov, V, Pickerodt, P, Falk, R, Mahlau, A, Lee, A, Inglis, R, Morgan, R, Barker, G, Kamata, K, Abe, T, Saitoh, D, Tokuda, Y, Butler, M, Hwa, H, Gil, L, Vaquero, R, Rodriguez Ruiz, E, Lago, A, Allut, J, Gestal, A, Thomas Rüddel, D, Schwarzkopf, D, Fleischmann, C, Reinhart, K, Suwanpasu, S, Sattayasomboon, Y, Filho, N, Oliveira, J, Ballalai, C, De Lucia, C, Araponga, G, Veiga, L, Silva, C, Garrido, M, Ramos, B, Ricaldi, E, Gomes, S, Wright, C, Docking, R, Doherty, P, Black, E, Stenhouse, P, Plummer, M, Finnis, M, Phillips, L, Kar, P, Bihari, S, Biradar, V, Moodie, S, Horowitz, M, Shaw, J, Yatabe, T, Inoue, S, Sakaguchi, M, Egi, M, Abdelhamid, Y, Hokka, M, Mizobuchi, S, Giersch, E, Summers, M, Hatzinikolas, S, Heller, S, Jones, K, Schweizer, R, Jacquet Lagreze, M, Portran, P, Junot, S, Allaouchiche, B, Fellahi, J, Guerci, P, Ergin, B, Kapucu, A, Ince, C, Crisman, M, Shinotsuka, C, Fagnoul, D, Orbegozo, D, Preiser, J, Thooft, A, Brimioulle, S, Iwasaka, H, Tahara, S, Nagamine, M, Ichigatani, A, Cabrera, A, Zepeda, E, Granillo, J, Sánchez, J, Montoya, A, Montenegro, A, Blanco, G, Robles, C, Drolz, A, Horvatits, T, Roedl, K, Rutter, K, Funk, G, Schneeweiss, B, Fuhrmann, V, Sabetian, G, Pooresmaeel, F, Ghaffaripour, S, Farbod, A, Tabei, H, Taheri, L, Anandanadesan, R, Metaxa, V, Teixeira, C, Pereira, S, Hernández Marrero, P, Carvalho, A, Beckmann, M, Hartog, C, Raadts, A, Robertsen, A, Førde, R, Skaga, N, Helseth, E, Honeybul, S, Ho, K, Lopez, P, Ortega, P, Sola, E, Spasova, T, Kopecky, O, Rusinova, K, Waldauf, P, Cepeplikova, Z, Domínguez, J, Almudevar, P, Carmona, S, Muñoz, J, Castañeda, D, Abellán, A, Villamizar, P, Ramos, J, Pérez, L, Lucendo, A, Ejarque, M, Estella, A, Camps, V, Martín, M, Masnou, N, Barbosa, S, Varela, A, Palma, I, Cristina, L, Nunes, E, Pereira, I, Campello, G, Granja, C, Pande, R, Pandey, M, Varghese, S, Chanu, M, Van Dam, M, Ter Braak, E, Gracia, M, Viciana, R, Recuerda, M, Fontaiña, L, Tharmalingam, B, Kovari, F, Rose, L, Mcginlay, M, Amin, R, Burns, K, Connolly, B, Hart, N, Jouvet, P, Katz, S, Leasa, D, Mawdsley, C, Mcauley, D, Blackwood, B, Denham, S, Worrall, R, Arshad, M, Isherwood, P, Khadjibaev, A, Sabirov, D, Rosstalnaya, A, Parpibaev, F, Sharipova, V, Guzman, C, Cha, Y, Lee, S, Tyagi, N, Rajput, R, Taneja, S, Singh, V, Sharma, S, Mittal, S, Rao, B, Ayachi, J, Fraj, N, Romdhani, S, Khedher, A, Meddeb, K, Sma, N, Azouzi, A, Bouneb, R, Chouchene, I, El Ghardallou, M, Boussarsar, M, Jennings, R, Walter, E, Ribeiro, J, Moniz, I, Marçal, R, Santos, A, Candeias, C, E. Silva, Z, Gomez, S, Nieto, O, Gonzalez, J, Cuellar, A, Mildh, H, Pettilä, V, Korhonen, A, Karlsson, S, Ala Kokko, T, Reinikainen, M, Vaara, S, Zaleska Kociecka, M, Grabowski, M, Dąbrowski, M, Wozniak, S, Piotrowska, K, Banaszewski, M, Imiela, J, Stepinska, J, Pérez, A, Ordoñez, P, Giribet, A, Cuervo, M, Cuervo, R, Esteban, M, Fraile, L, Mittelbrum, C, Albaiceta, G, Koeze, J, Keus, F, Dieperink, W, van der Horst, I, van Meurs, M, Zijlstra, J, Roberts, S, Caballero, C, Isgro, G, Hall, D, Beitland, S, Trøseid, A, Brusletto, B, Waldum Grevbo, B, Berg, J, Sunde, K, Huertas, D, Manzano, F, Quintana, M, Osuna, A, Santiago Ruiz, F, Rodríguez Mejías, C, Wangensteen, R, Jamaati, H, Hashemian, S, Abbasi, G, Khaloo, V, Tabei, S, Kafilzadeh, A, Bakhodaei, H, Diaz, J, Silva, R, Garcia, D, Luis, E, Gomez, M, Soriano, R, Gonzalez, P, Ibrahim, I, Rafik, M, Al Ansary, A, Algendi, M, Ali, A, Benten, D, Kluwe, J, Siedler, S, Adedugbe, I, Bird, G, Kennedy, R, Yugi, G, Haroon, B, Witter, T, Khaliq, W, 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Braun, W, Walter, M, Francis, R, Lachmann, B, Leonhardt, S, Landaverde López, A, Canedo Castillo, N, Esquivel Chávez, A, Arvizu Tachiquín, P, Baltazar Torres, J, Cardoso, V, Krystopchuk, A, Castro, S, Melão, L, Firmino, S, Marreiros, A, Almaziad, S, Kubbara, A, Barnett, W, Nakity, R, Alamoudi, W, Altook, R, Tarazi, T, Fida, M, Safi, F, Assaly, R, Santini, A, Milesi, M, Maraffi, T, Pugni, P, Cavenago, M, Gattinoni, L, Protti, A, Perchiazzi, G, Borges, J, Bayat, S, Porra, L, Broche, L, Hedenstierna, G, Larsson, A, Roneus, A, Segelsjö, M, Vestito, M, Gremo, E, Nyberg, A, Castegren, M, Pikwer, A, Yoshida, T, Engelberts, D, Otulakowski, G, Katira, B, Post, M, Amato, M, Koch, N, Hoellthaler, J, Mair, S, Phillip, V, Beitz, A, Baladrón, V, Villarejo, P, Steenstra, R, Banierink, H, Hof, J, Hoekstra, M, Sterz, F, Horvatits, K, Herkner, H, Kott, M, Zitta, K, Brandt, B, Schildhauer, C, Elke, G, Hummitzsch, L, Albrecht, M, González, L, Alonso, D, Sánchez, R, Lucas, J, Ferlitsch, A, Fauler, G, Trauner, M, Pischke, S, Fischer, L, Thaiss, F, Koch, M, Bangert, K, Lohse, A, Nashan, B, Sterneck, M, Faenza, S, Siniscalchi, A, Pierucci, E, Mancini, E, Ricci, D, Gemelli, C, Cuoghi, A, Magnani, S, Atti, M, Sotos, F, Cánovas, J, López, A, Burruezo, A, Torres, D, Herrera Gutierrez, M, Barrueco Francioni, J, Arias Verdú, D, Lozano Saez, R, Quesada Garcia, G, Seller Pérez, G, Figueiredo, A, Anzola, Y, Pereira, R, Bento, L, Lai, M, Deiana, M, Seller Perez, G, Vardas, K, Ilia, S, Sertedaki, A, Charmadari, E, Stratakis, C, Briassouli, E, Goukos, D, Psarra, K, Botoula, E, Tsagarakis, S, Mageira, E, Routsi, C, Nanas, S, Campello, E, Radu, C, Su, H, Lam, Y, Willis, K, Pullar, V, Hubner, R, Tsang, J, de Guadiana Romualdo, L, Rebollo Acebes, S, Esteban Torrella, P, Jiménez Sánchez, R, Jiménez Santos, E, Ortín Freire, A, Hernando Holgado, A, Albaladejo Otón, M, Coelho, L, Rabello, L, Póvoa, P, Varis, E, Poukkanen, M, Jacob, S, Takala, J, Wilkman, E, Lundberg, O, Bergenzaun, L, Rydén, J, Rosenqvist, M, Melander, O, Chew, M, Kishihara, Y, Yasuda, H, Jimenez, R, Torrella, P, Fernandez, A, Sanchez, S, Ortin, A, Prats, R, Aguilera, E, Marti, D, Fernandez, L, Ferrer, M, Lanziotti, V, Pulcheri, L, Ribeiro, M, Barbosa, A, E. Silva, J, Soares, M, Marqués, M, Moreno, A, Pizarraya, A, Smani, Y, Connell, M, Zhang, L, Parker, R, Banerjee, I, Clermont, G, Norberg, E, Oras, J, Cuisinier, A, Maufrais, C, Payen, J, Nottin, S, Walther, G, Arib, S, Bilotta, F, Badenes, R, Rubulotta, F, Mirek, S, Monfort, B, Stazi, E, Roig, A, Magnoni, S, Marando, M, Pifferi, S, Conte, V, Ortolano, F, Carbonara, M, Bertani, G, Scola, E, Cadioli, M, Triulzi, F, Colombo, A, Stocchetti, N, Rotzel, H, Lázaro, A, Prada, D, Guimillo, M, Piqueras, C, Guia, J, Simon, M, Arizmendi, A, Carratalá, A, El Maraghi, S, Yehia, A, Bakry, M, Shoman, A, Backes, F, Bianchin, M, Vieira, S, de Souza, A, Backes, A, Klein, C, Arunkumar, A, Lozano, A, Gallaher, C, Cattlin, S, Gordon, S, Picard, J, Fontana, V, Bond, O, Nobile, L, Mrozek, S, Delamarre, L, Capilla, F, Al Saati, T, Fourcade, O, Dominguez Berrot, A, Gonzalez Vaquero, M, Vallejo Pascual, M, Gupta, D, Ivory, B, Chopra, M, Mccarthy, J, Felderhof, C, Macneil, C, Maggiorini, M, Duska, F, Fumis, R, Junior, J, Amarante, G, Skorko, A, Sanders, S, Aron, J, Kroll, R, Redfearn, C, Krishnan, P, Khalil, J, Kongpolprom, N, Gulia, V, Lourenço, E, Duro, C, Baptista, G, Alves, A, Arminda, B, Rodrigues, M, Hayward, J, Baldwin, F, Gray, R, Katinakis, P, Stijf, M, Ten Kleij, M, Jansen Frederiks, M, Broek, R, de Bruijne, M, Spronk, P, Sinha, K, Luney, M, Palmer, K, Keating, L, Abu Habsa, M, Bahl, R, Baskaralingam, N, Ahmad, A, Kanapeckaite, L, Bhatti, P, Glace, S, Jeyabraba, S, Lewis, H, Kostopoulos, A, Raja, M, West, A, Ely, A, Turkoglu, L, Zolfaghari, P, Baptista, J, Marques, M, Martins, P, Pimentel, J, Su, Y, Villacres, S, Stone, M, Parsikia, A, Medar, S, O'Dea, K, Porter, J, Tirlapur, N, Jonathan, J, Singh, S, Takata, M, Mcwhirter, E, Lyon, R, Hariz, M, Azmi, E, Alkhan, J, Movsisyan, V, Petrikov, S, Marutyan, Z, Aliev, I, Evdokimov, A, Antonucci, E, Merz, T, Hartmann, C, Calzia, E, Radermacher, P, Nußbaum, B, Huber Lang, M, Gröger, M, Svoren Jabalera, E, Davenport, E, Humburg, P, Knight, J, Hinds, C, Jun, I, Kim, W, Besch, G, Perrotti, A, Puyraveau, M, Baltres, M, Samain, E, Chocron, S, Pili Floury, S, Plata Menchaca, E, Sabater Riera, J, Estruch, M, Boza, E, Toscana Fernández, J, Bruguera Pellicer, E, Ordoñez Llanos, J, Pérez Fernández, X, Cavaleiro, P, Tralhão, A, Arrigo, M, Lopes, J, Lebrun, M, Cholley, B, Perezvela, J, Marinmateos, H, Rivera, J, Llorente, M, De Marcos, B, Fernandez, F, Laborda, C, Zamora, D, Delgado, J, Imperiali, C, Dastis, M, Górka, J, Górka, K, Iwaniec, T, Frołow, M, Polok, K, Fronczek, J, Kózka, M, Musiał, J, Szczeklik, W, Sileli, M, Moursia, C, Maleoglou, H, Leleki, K, Uz, Z, Ince, Y, Papatella, R, Bulent, E, De Mol, B, Vicka, V, Gineityte, D, Ringaitiene, D, Norkiene, I, Sipylaite, J, Möller, C, Thomas Rueddel, D, Vlasakov, V, Rochwerg, B, Theurer, P, Al Sibai, J, Camblor, P, Fernandez, P, Gala, J, Guisasola, J, Tamura, T, Miyajima, I, Yamashita, K, Yokoyama, M, Dalampini, E, Nastou, M, Baddour, A, Ignatiadis, A, Asteri, T, Hathorn, K, Purtle, S, Viana, M, Tonietto, T, Gross, L, Costa, V, Tavares, A, Lisboa, B, Moraes, R, Viana, L, Azevedo, M, Ceniccola, G, Pequeno, R, Holanda, T, Mendonça, V, Araújo, W, Carvalho, L, Segaran, E, Vickers, L, Brinchmann, K, Wignall, I, De Brito Ashurst, I, Del Olmo, R, Vaquerizo, C, Carreño, R, Gálvez, V, Kaminsky, G, Nieto, B, Fuentes, M, De la Torre, M, Torres, E, Alonso, A, Velayos, C, Saldaña, T, Escribá, A, Grip, J, Kölegård, R, Sundblad, P, Rooyackers, O, Naser, B, Jaziri, F, Jazia, A, Barghouth, M, Hentati, O, Skouri, W, El Euch, M, Mahfoudhi, M, Turki, S, Abdelghni, K, Abdallah, B, Maha, B, Lorente, M, Włudarczyk, A, Hałek, A, Bargouth, M, Bennasr, M, Abdelghani, K, Abdallah, T, Geenen, I, Parienti, J, Shum, H, King, H, Yan, W, Londoño, J, Cardenas, C, Pedrosa, M, Gubianas, C, Bertolin, C, Batllori, N, Sirvent, J, Mukhopadhyay, A, Chan, H, Kowitlawakul, Y, Remani, D, Leong, C, Henry, C, Puthucheary, Z, Mendsaikhan, N, Begzjav, T, Lundeg, G, Dünser, M, Welsh, S, Guerra, E, Zerpa, M, Zechner, F, Berdaguer, F, Risso Vazquez, A, Masevicius, F, Greaney, D, Magee, A, Fitzpatrick, G, Lugo Cob, R, Tejeda Huezo, B, Cano Oviedo, A, Aydogan, M, Togal, T, Taha, A, Chai, H, Kam, C, Razali, S, Sivasamy, V, Kuan, L, Morales, M, Pires, T, and Azevedo, L

Subjects
intracerebral haemorrhage in intensive care
Published
2016

37. Venoarterial extracorporeal membrane oxygenation after coronary artery bypass grafting:results of a multicenter study

Author

Biancari, F. (Fausto), Dalén, M. (Magnus), Perrotti, A. (Andrea), Fiore, A. (Antonio), Reichart, D. (Daniel), Khodabandeh, S. (Sorosh), Gulbins, H. (Helmut), Zipfel, S. (Svante), Al Shakaki, M. (Mosab), Welp, H. (Henryk), Vezzani, A. (Antonella), Gherli, T. (Tiziano), Lommi, J. (Jaakko), Juvonen, T. (Tatu), Svenarud, P. (Peter), Chocron, S. (Sidney), Verhoye, J. P. (Jean Philippe), Bounader, K. (Karl), Gatti, G. (Giuseppe), Gabrielli, M. (Marco), Saccocci, M. (Matteo), Kinnunen, E.-M. (Eeva-Maija), Onorati, F. (Francesco), Santarpino, G. (Giuseppe), Alkhamees, K. (Khalid), Ruggieri, V. G. (Vito G.), and Dell'Aquila, A. M. (Angelo M.)

Subjects
surgical procedures, operative, Post-cardiotomy, Extracorporeal membrane oxygenation, Coronary artery bypass, Heart failure, ECMO, ECLS, CABG, Extracorporeal life support
Abstract

Background: The evidence of the benefits of using venoarterial extracorporeal membrane oxygenation (VA-ECMO) after coronary artery bypass grafting (CABG) is scarce. Methods: We analyzed the outcomes of patients who received VA-ECMO therapy due to cardiac or respiratory failure after isolated CABG in 12 centers between 2005 and 2016. Patients treated preoperatively with ECMO were excluded from this study. Results: VA-ECMO was employed in 148 patients after CABG for median of 5.0 days (mean, 6.4, SD 5.6 days). In-hospital mortality was 64.2%. Pooled in-hospital mortality was 65.9% without significant heterogeneity between the centers (I2 8.6%). The proportion of VA-ECMO in each center did not affect in-hospital mortality (p = 0.861). No patients underwent heart transplantation and six patients received a left ventricular assist device. Logistic regression showed that creatinine clearance (p = 0.004, OR 0.98, 95% CI 0.97–0.99), pulmonary disease (p = 0.018, OR 4.42, 95% CI 1.29–15.15) and pre-VA-ECMO blood lactate (p = 0.015, OR 1.10, 95% CI 1.02–1.18) were independent baseline predictors of in-hospital mortality. One-, 2-, and 3-year survival was 31.0%, 27.9%, and 26.1%, respectively. Conclusions: One third of patients with need for VA-ECMO after CABG survive to discharge. In view of the burden of resources associated with VA-ECMO treatment and the limited number of patients surviving to discharge, further studies are needed to identify patients who may benefit the most from this treatment.

Published
2017

38. ESICM LIVES 2016: part two

Author

Sivakumar, S., Taccone, F. S., Desai, K. A., Lazaridis, C., Skarzynski, M., Sekhon, M., Henderson, W., Griesdale, D., Chapple, L., Deane, A., Williams, L., Strickland, R., Lange, K., Heyland, D., Chapman, M., Rowland, M. J., Garry, P., Westbrook, J., Corkill, R., Antoniades, C. A., Pattinson, K. T., Fatania, G., Strong, A. J., Myers, R. B., Jermaine, C. M., Robertson, C. S., Rusin, C. G., Hofmeijer, J., Sondag, L., Tjepkema-Cloostermans, M. C., Beishuizen, A., Bosch, F. H., van Putten, M. J. A. M., Carteron, L., Patet, C., Solari, D., Oddo, M., Ali, M. A., Dias, C., Almeida, R., Vaz-Ferreira, A., Silva, J., Monteiro, E., Cerejo, A., Rocha, A. P., Elsayed, A. A., Abougabal, A. M., Beshey, B. N., Alzahaby, K. M., Pozzebon, S., Ortiz, A. Blandino, Cristallini, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Hravnak, M., Yousef, K., Chang, Y., Crago, E., Friedlander, R. M., Abdelmonem, S. A., Tahon, S. A., Helmy, T. A., Meligy, H. S., Puig, F., Dunn-Siegrist, I., Pugin, J., Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Tomar, D. S., Shafi, M., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Papakrivou, E. E., Makris, D., Manoulakas, E., Tsolaki, B., Karadodas, B., Zakynthinos, E., Garcia, I. Palacios, Martin, A. Diaz, Encinares, V. Sanchez, Ibañez, M. Pachón, Montero, J. Garnacho, Labrador, G., Cangueiro, T. Cebrero, Poulose, V., Koh, J., Kam, J. W., Yeter, H., Kara, A., Aktepe, O., Topeli, A., Tsolakoglou, I., Intas, G., Stergiannis, P., Kolaros, A. A., Chalari, E., Athanasiadou, E., Martika, A., Fildisis, G., Faivre, V., Mengelle, C., Favier, B., Payen, D., Poppe, A., Winkler, M. S., Mudersbach, E., Schreiber, J., Wruck, M. L., Schwedhelm, E., Kluge, S., Zöllner, C., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., la Torre, A. García-de, de la Torre-Prados, M. V., Tsvetanova-Spasova, T., Nuevo-Ortega, P., Rueda-Molina, C., Fernández-Porcel, A., Camara-Sola, E., Salido-Díaz, L., García-Alcántara, A., Meleti, D. E., Suberviola, B., Riera, J., Rellan, L., Sanchez, M., Robles, J. C., Lopez, E., Vicente, R., Miñambres, E., Santibañez, M., Le Guen, M., Moore, J., Mason, N., Windpassinger, M., Plattner, O., Mascha, E., Sessler, D. I., Research, Outcomes, Melia, U., Fontanet, J., van den Berg, J. P., Struys, M. M. R. F., Vereecke, H. E. M., Jensen, E. W., Rood, P. J. T., van de Schoor, F., van Tertholen, K., Pickkers, P., van den Boogaard, M., Beardow, Z. J., Redhead, H., Paramasivam, K., Numan, T., Kamper, A. M., Rood, P., Peelen, L. M., Zeman, P. M., Slooter, A. J., van Ewijk, C. E., Jacobs, G. E., Girbes, A. R. J., Myatra, S. N., Harish, M. M., Prabu, N. R., Siddiqui, S., Kulkarni, A. P., Divatia, J. V., Murbach, L. D., Leite, M. A., Osaku, E. F., Costa, C. R. L. M., Pelenz, M., Neitzke, N. M., Moraes, M. M., Jaskowiak, J. L., Silva, M. M. M., Zaponi, R. S., Abentroth, L. R. L., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Hernández-Sánchez, N., Sánchez-Hurtado, L. A., García-Guillen, F. J., Ñamendys-Silva, S. A., Maghsoudi, B., Emami, M., Khosravi, M. B., Zand, F., Tabatabaie, H. R., Masjedi, M., Sabetiyan, G., Mokri, A., Troubleyn, J., Diltoer, M., Jacobs, R., Nguyen, D. N., De Waele, E., De Regt, J., Honoré, P. M., Van Gorp, V., Spapen, H. D., Contreras, R. S., Toapanta, N. D., Moreno, G., Sabater, J., Torrado, H., Gonzalez, M., Marin, M., Farigola, E., Gonzalez, A., Fernandez, J., Vera, A., Gisbert, X., Juliá, C., Uya, J., Corral, L., Elias-Jones, I., Gemmell, L., MacKay, A., Randall, D., Adwaney, A., Blunden, M., Prowle, J. R., Kirwan, C. J., Thomas, N., Martin, A., Owen, H., Darwin, L., Conway, D., Atkinson, D., Sharman, M., Barbanti, C., Amour, J., Gaudard, P., Rozec, B., Mauriat, P., M’rini, M., Leger, P. L., Cambonie, G., Liet, J. M., Girard, C., Laroche, S., Damas, P., Assaf, Z., Loron, G., Lecourt, L., Pouard, P., Prowle, J.R., Kim, S. H., Na, S., Kim, J., Oh, S. Y., Jung, C. W., Yoo, S. H., Min, S. H., Chung, E. J., Lee, H., Lee, N. J., Lee, K. W., Suh, K. S., Ryu, H. G., Marshall, D. C., Goodson, R. J., Salciccioli, J. D., Shalhoub, J., Potter, E. K., Kirk-Bayley, J., Karanjia, N. D., Forni, L. G., Creagh-Brown, B. C., Bossy, M., Nyman, M., Tailor, A., Creagh-Brown, B., D’Antini, D., Spadaro, S., Valentino, F., Sollitto, F., Cinnella, G., Mirabella, L., Calvo, F. J. Redondo, Bejarano, N., Padilla, D., Baladron, V., Villajero, P., Villazala, R., Redondo, J., Yuste, A. S., Liu, J., Shen, F., Teboul, J. L., Anguel, N., Beurton, A., Bezaz, N., Richard, C., Monnet, X., Fossali, T., Colombo, R., Ottolina, D., Rossetti, M., Mazzucco, C., Marchi, A., Porta, A., Catena, E., Tollisen, K. H., Andersen, G. Ø., Heyerdahl, F., Jacobsen, D., de Waard, M. C., van IJzendoorn, M. C. O., Buter, H., Kingma, W. P., Navis, G. J., Boerma, E. C., Rulisek, J., Balik, M., Zacharov, S., Kim, H. S., Jeon, S. J., Namgung, H., Lee, E., Cho, Y. J., Lee, Y. J., Huang, A., Cioccari, L., Luethi, N., Mårtensson, J., Bellomo, R., Forsberg, M., Edman, G., Höjer, J., Forsberg, S., Freile, M. T. Chiquito, Hidalgo, F. N., Molina, J. A. Martinez, Lecumberri, R., Rosselló, A. Figuerola, Travieso, P. Medrano, Leon, G. Tuero, Sanchez, J. Gonzalez, Frias, L. Sahuquillo, Rosello, D. Balsells, Verdejo, J. A. Garcia, Serrano, J. A. Noria, Winterwerp, D., van Galen, T., Vazin, A., Karimzade, I., Zand, A., Ozen, E., Ekemen, S., Akcan, A., Sen, E., Yelken, B. Buyukkidan, Kureshi, N., Fenerty, L., Thibault-Halman, G., Erdogan, M., Walling, S., Green, R. S., Clarke, D. 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T., Russ, M., Braun, W., Walter, M., Francis, R., Lachmann, B., Leonhardt, S., Landaverde-López, A., Canedo-Castillo, N. A., Esquivel-Chávez, A., Arvizu-Tachiquín, P. C., Baltazar-Torres, J. A., Cardoso, V., Krystopchuk, A., Castro, S., Melão, L., Firmino, S., Marreiros, A., Almaziad, S., Kubbara, A., Barnett, W., Nakity, R., Alamoudi, W., Altook, R., Tarazi, T., Fida, M., Safi, F., Assaly, R., Santini, A., Milesi, M., Maraffi, T., Pugni, P., Cavenago, M., Gattinoni, L., Protti, A., Perchiazzi, G., Borges, J. B., Bayat, S., Porra, L., Broche, L., Hedenstierna, G., Larsson, A., Roneus, A., Segelsjö, M., Vestito, M. C., Gremo, E., Nyberg, A., Castegren, M., Pikwer, A., Yoshida, T., Engelberts, D., Otulakowski, G., Katira, B., Post, M., Brochard, L., Amato, M. B. P., Koch, N., Hoellthaler, J., Mair, S., Phillip, V., Beitz, A., Baladrón, V., Villarejo, P., Steenstra, R. J., Banierink, H., Hof, J., van der Horst, I. C., Nijsten, M. W., Hoekstra, M., Sterz, F., Horvatits, K., Herkner, H., Kott, M., Zitta, K., Brandt, B., Schildhauer, C., Elke, G., Hummitzsch, L., Albrecht, M., González, L. Rey, Alonso, D. Cabestrero, Sánchez, R. de Pablo, Lucas, J. Higuera, Ferlitsch, A., Fauler, G., Trauner, M., Pischke, S., Fischer, L., Thaiss, F., Koch, M., Bangert, K., Lohse, A. W., Nashan, B., Sterneck, M., Faenza, S., Siniscalchi, A., Pierucci, E., Mancini, E., Ricci, D., Gemelli, C., Cuoghi, A., Magnani, S., Atti, M., Sotos, F., Cánovas, J., López, A., Burruezo, A., Torres, D., Herrera-Gutierrez, M. E., Barrueco-Francioni, J., Arias-Verdú, D., Lozano-Saez, R., Quesada-Garcia, G., Seller-Pérez, G., Figueiredo, A., Anzola, Y., Pereira, R., Bento, L., Lai, M., Deiana, M., Seller-Perez, G., Vardas, K., Ilia, S., Sertedaki, A., Charmadari, E., Stratakis, C. A., Briassouli, E., Goukos, D., Psarra, K., Botoula, E., Tsagarakis, S., Mageira, E., Routsi, C., Nanas, S., Campello, E., Radu, C. M., Su, H., Lam, Y. M., Willis, K., Pullar, V., Hubner, R. P., Tsang, J. L., de Guadiana-Romualdo, L. García, Rebollo-Acebes, S., Esteban-Torrella, P., Jiménez-Sánchez, R., Jiménez-Santos, E., Ortín-Freire, A., Hernando-Holgado, A., Albaladejo-Otón, M. D., Coelho, L., Rabello, L., Póvoa, P., Varis, E., Poukkanen, M., Jacob, S., Takala, J., Wilkman, E., Lundberg, O. H. M., Bergenzaun, L., Rydén, J., Rosenqvist, M., Melander, O., Chew, M. S., Kishihara, Y., Yasuda, H., Jimenez, R., Torrella, P. Esteban, Fernandez, A., Sanchez, S., Ortin, A., Prats, R. Guillamat, Aguilera, E., Marti, D., Fernandez, L., Ferrer, M., Lanziotti, V. S., Pulcheri, L., Ribeiro, M. O., Barbosa, A. P., e Silva, J. R. Lapa, Soares, M., Salluh, J. I. F., Marqués, M. Gil, Moreno, A. Puppo, Pizarraya, A. Gutierrez, Diaz, J. Pachón, Smani, Y., Connell, M. Mc, Zhang, L. A., Parker, R. S., Banerjee, I., Clermont, G., Norberg, E., Oras, J., Cuisinier, A., Maufrais, C., Payen, J. F., Nottin, S., Walther, G., Arib, S., Bilotta, F., Badenes, R., Rubulotta, F., Mirek, S., Monfort, B., Stazi, E., Roig, A. Lozano, Magnoni, S., Marando, M., Pifferi, S., Conte, V., Ortolano, F., Carbonara, M., Bertani, G., Scola, E., Cadioli, M., Triulzi, F., Colombo, A., Stocchetti, N., Rotzel, H. B., Lázaro, A. Serrano, Prada, D. Aguillón, Guimillo, M. Rodriguez, Piqueras, C. Sanchís, Guia, J. Romero, Simon, M. García, Arizmendi, A. Mesejo, Carratalá, A., El Maraghi, S., Yehia, A., Bakry, M., Shoman, A., Backes, F. N., Bianchin, M. M., Vieira, S. R. R., de Souza, A., Backes, A. N., Klein, C., Arunkumar, A. S., Lozano, A., Gallaher, C., Cattlin, S., Gordon, S., Picard, J., Fontana, V., Bond, O., Nobile, L., Mrozek, S., Delamarre, L., Capilla, F., Al-Saati, T., Fourcade, O., Dominguez-Berrot, A. M., Gonzalez-Vaquero, M., Vallejo-Pascual, M. E., Gupta, D., Ivory, B. D., Chopra, M., McCarthy, J., Felderhof, C. L., MacNeil, C., Maggiorini, M., Duska, F., Fumis, R. R. L., Junior, J. M. Vieira, Amarante, G., Skorko, A., Sanders, S., Aron, J., Kroll, R. J., Redfearn, C., Krishnan, P., Khalil, J. E., Kongpolprom, N., Gulia, V., Lourenço, E., Duro, C., Baptista, G., Alves, A., Arminda, B., Rodrigues, M., Hayward, J., Baldwin, F., Gray, R., Katinakis, P. A., Stijf, M., Ten Kleij, M., Jansen-Frederiks, M., Broek, R., de Bruijne, M., Spronk, P. E., Sinha, K., Luney, M., Palmer, K., Keating, L., Abu-Habsa, M., Bahl, R., Baskaralingam, N., Ahmad, A., Kanapeckaite, L., Bhatti, P., Glace, S., Jeyabraba, S., Lewis, H. F., Kostopoulos, A., Raja, M., West, A., Ely, A., Turkoglu, L. M., Zolfaghari, P., Baptista, J. P., Marques, M. P., Martins, P., Pimentel, J., Su, Y. C., Villacres, S., Stone, M. E., Parsikia, A., Medar, S., O’Dea, K. P., Porter, J., Tirlapur, N., Jonathan, J. M., Singh, S., Takata, M., McWhirter, E., Lyon, R., Hariz, M. L., Azmi, E., Alkhan, J., Movsisyan, V., Petrikov, S., Marutyan, Z., Aliev, I., Evdokimov, A., Antonucci, E., Merz, T., Hartmann, C., Calzia, E., Radermacher, P., Nußbaum, B., Huber-Lang, M., Gröger, M., Svoren-Jabalera, E., Davenport, E. E., Humburg, P., Knight, J., Hinds, C. J., Jun, I. J., Kim, W. J., Lee, E. H., Besch, G., Perrotti, A., Puyraveau, M., Baltres, M., Samain, E., Chocron, S., Pili-Floury, S., Plata-Menchaca, E. P., Sabater-Riera, J., Estruch, M., Boza, E., Toscana-Fernández, J., Bruguera-Pellicer, E., Ordoñez-Llanos, J., Pérez-Fernández, X. L., Cavaleiro, P., Tralhão, A., Arrigo, M., Lopes, J.-P., Lebrun, M., Cholley, B., PerezVela, J. L., MarinMateos, H., Rivera, J. J. Jimenez, Llorente, M. A. Alcala, De Marcos, B. Gonzalez, Fernandez, F. J. Gonzalez, Laborda, C. Garcia, Zamora, D. Fernandez, Delgado, J. C. Lopez, Imperiali, C., Dastis, M., Górka, J., Górka, K., Iwaniec, T., Frołow, M., Polok, K., Fronczek, J., Kózka, M., Musiał, J., Szczeklik, W., Sileli, M., Moursia, C., Maleoglou, H., Leleki, K., Uz, Z., Ince, Y., Papatella, R., Bulent, E., De Mol, B., Vicka, V., Gineityte, D., Ringaitiene, D., Norkiene, I., Sipylaite, J., Möller, C., Thomas-Rueddel, D. O., Vlasakov, V., Rochwerg, B., Theurer, P., Al Sibai, J. Zanabili, Camblor, P. Martinez, Fernandez, P. Alvarez, Gala, J. M. García, Guisasola, J. Silba, Tamura, T., Miyajima, I., Yamashita, K., Yokoyama, M., Dalampini, E., Nastou, M., Baddour, A., Ignatiadis, A., Asteri, T., Hathorn, K. E., Purtle, S. W., Viana, M. V., Tonietto, T. A., Gross, L. A., Costa, V. L., Tavares, A. L. J., Lisboa, B. O., Moraes, R. B., Vieira, S. R., Viana, L. V., Azevedo, M. J., Ceniccola, G. D., Pequeno, R. S. F., Holanda, T. P., Mendonça, V. S., Araújo, W. M. C., Carvalho, L. S. F., Segaran, E., Vickers, L., Brinchmann, K., Wignall, I., De Brito-Ashurst, I., del Olmo, R., Esteban, M. J., Vaquerizo, C., Carreño, R., Gálvez, V., Kaminsky, G., Nieto, B., Fuentes, M., De la Torre, M. A., Torres, E., Alonso, A., Velayos, C., Saldaña, T., Escribá, A., GRIP, J., Kölegård, R., Sundblad, P., Rooyackers, O., Naser, Ben, Jaziri, F., Jazia, A. Ben, Barghouth, M., Hentati, O., Skouri, W., El Euch, M., Mahfoudhi, M., Turki, S., Abdelghni, K. Ben, Abdallah, Ben, Maha, B. N. M., Lorente, M., Włudarczyk, A., Hałek, A., Bargouth, M., Bennasr, M., Abdelghani, K. Ben, Abdallah, T. Ben, Geenen, I. L., Parienti, J. J., Straaten, H. M. Oudemans-van, Shum, H. P., King, H. S., Chan, K. C., Yan, W. W., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Pedrosa, M. Morales, Gubianas, C. Murcia, Bertolin, C. Fuster, Batllori, N. Vila, Sirvent, J. M., Mukhopadhyay, A., Chan, H. Y., Kowitlawakul, Y., Remani, D., Leong, C. S. F., Henry, C. J., Puthucheary, Z. A., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M., Welsh, S. P., Guerra, E., Zerpa, M. C. l., Zechner, F., Berdaguer, F., Risso-Vazquez, A., Masevicius, F. D., Greaney, D., Magee, A., Fitzpatrick, G., Lugo-Cob, R. G., Tejeda-Huezo, B. C., Cano-Oviedo, A. A., Aydogan, M. S., Togal, T., Taha, A., Chai, H. Z., Kam, C., Razali, S. S. Yang, Sivasamy, V., Kuan, L. Y., Morales, M. A. Lopez, Pires, T., and Azevedo, L. C. P.

Subjects
Meeting Abstracts
Abstract

Introduction In addition to systemic hemodynamics, the management\ud of neurocritically ill patients is often informed by neuromonitoring. In\ud the absence of high-level evidence clinicians are often guided by personal\ud and local expertise. Little is known about practices as they pertain\ud to the use of such monitoring in patients with acute brain injury (ABI).\ud Objectives To investigate practices in bedside monitoring for ABI patients.\ud Particularly interested in differences among “neurointensivists”\ud (NIs; defined here as intensivists whose clinical practice is comprised\ud > 1/3 by neurocritical care) and other intensivists (OIs). Also, to\ud explore patterns specific to traumatic brain injury (TBI) and subarachnoid\ud hemorrhage (SAH), as well as preferences and availability of\ud particular technologies/devices.\ud Methods Electronic survey of 22 items including two case-based scenarios;\ud endorsed by SCCM (9,000 recipients) and ESICM (on-line\ud newsletter) in 2013. A sample size of 370 was calculated based on a\ud population of 10,000 physician members, a 5 % margin error, and\ud 95 % confidence interval. We summarized results using descriptive\ud statistics (proportions with 95 % confidence intervals). A chi-square\ud test was used to compare proportions of responses between NIs and\ud OIs with a significance p < 0.05.\ud Results There were 655 responders (66 % completion rate); 422(65 %)\ud were classified as OIs and 226(35 %) as NIs. More NIs follow\ud hemodynamic protocols for neurocritically-ill patients (56 % vs. 43 %, p\ud 0.001), in TBI (44.5 % vs. 33.3 %, p 0.007), and in SAH (38.1 % vs. 21.3 %,\ud p < 000.1). For delayed cerebral ischemia (DCI), more NIs target cardiac\ud index (CI) (35 % vs. 21 %, p 0.0001), and fluid responsiveness (62 % vs.\ud 53 %, p 0.03), use more bedside ultrasound (BUS) (42 % vs. 29 %, p\ud 0.005) and arterial waveform analysis (40 % vs. 29 %, p 0.02). For DCI\ud neuromonitoring, NIs use more angiography (57 % vs. 43 %, p 0.004),\ud TCD (46 % vs. 38 %, p 0.0001), and CTP (32 % vs.16 %, p 0.0001). For\ud CPP optimization in TBI, NIs use more arterial waveform analysis (45 %\ud vs. 35 %, p 0.019), and BUS (37 % vs. 27.7 %, p 0.023), while more OIs\ud monitor mixed venous oxygen saturation (54.1 % vs. 45 %, p 0.045). For\ud TBI neuromonitoring, NIs use more PbtO2 (28 % vs. 10 %, p 0.0001). In\ud the case scenario of raised ICP/low PbtO2, most employ analgosedation\ud (47 %) and osmotherapy (38 %). Fewer make use of preserved pressure\ud reactivity, particularly OIs (vasopressor use 23 % vs. 34 %, p 0.014).\ud Conclusions There is large heterogeneity in the use of monitoring protocols,\ud variables, and technologies/devices. “Neurointensivists” not only\ud employ more neuromonitoring but also more hemodynamic monitoring\ud in patients with acute brain injury. ICP/CPP remain the most commonly\ud followed neuro-variables in TBI patients, with low use of other\ud brain-physiology parameters, sugg

Published
2016

41. Balloon Expandable Transaortic Transcatheter Valve Implantation with or without Predilation of the Aortic Valve: Results from a Multicenter, Multinational Prospective Registry (ROUTE)

Author

Kofler, M., additional, Dumfarth, J., additional, Frank, D., additional, Cocchieri, R., additional, Jagielak, D., additional, Aiello, M., additional, Lapeze, J., additional, Laine, M., additional, Chocron, S., additional, Muir, D., additional, Eichinger, W., additional, Thielmann, M., additional, Labrousse, L., additional, Bapat, V., additional, Arne, K., additional, Verhoye, J.P., additional, Gerosa, G., additional, Baumbach, H., additional, Bamlage, P., additional, Deutsch, C., additional, Thoenes, M., additional, Romano, M., additional, and Bonaros, N., additional

Published
2017
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42. The French National Registry (N.O.E.) of elective frozen elephant trunk surgery using the Evita Open Plus: early and mid-term outcomes

Author

Verhoye, J.P., primary, Anselmi, A., additional, Belhaj, R., additional, Farhat, F., additional, Couetil, J.P., additional, Caus, T., additional, Chocron, S., additional, Choukroun, E., additional, Bezon, E., additional, Grisoli, D., additional, Demaria, R., additional, Maureira, P., additional, Jayle, C., additional, Leprince, P., additional, Mirza, A., additional, Bischoff, N., additional, Kretz, J.G., additional, and Fouquet, O., additional

Published
2017
Full Text
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43. Risk Factors and Complications Affecting Hospital Outcome after Redo Mitral Surgery

Author

Onorati, F., primary, Reichart, D., additional, Perrotti, A., additional, Mariscalo, G., additional, Della Ratta, E., additional, Santarpino, G., additional, Salsano, A., additional, Rubino, A., additional, Biancari, F., additional, Beghi, C., additional, De Feo, M., additional, Mignosa, C., additional, Fischlein, T., additional, Chocron, S., additional, Detter, C., additional, Santini, F., additional, Reichenspurner, H., additional, and Faggian, G., additional

Published
2016
Full Text
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46. A constitutive model for In situ comminuted silicon carbide

Author

Anderson, C.E., Chocron, S., Behner, T., and Publica

Abstract

Cylindrical hot-pressed silicon carbide (SiC) ceramic targets were predamaged before ballistic testing. The SiC was thermally shocked to introduce noncontiguous cracks, then additional damage was induced by load-unload cycling in an MTS machine while the ceramic specimen was confined in a 7075-T6 aluminum sleeve. Long gold rod penetration was measured as a function of impact velocity nu(P) over the approximate range of 1-3 km/s, with most data between 1.5 and 3 km/s. Penetration as a function of time was measured using multiple, independently timed flash X-rays. It was assumed that the penetration response of the damaged SiC could be represented by a Drucker-Prager constitutive model. Numerical simulations were used to estimate the constitutive constants. It was found that simulations could not be used to determine a unique set of constitutive constants within experimental data scatter.

Published
2009

47. Angiotensin-converting enzyme inhibition in patients with coronary artery disease and preserved left ventricular function: Ischemia Management with Accupril post-bypass graft via inhibition of angiotensin-converting enzyme (IMAGINE) compared with the other major trials in coronary- artery disease

Author

van Gilst, WH, Warnica, JW, Baillot, R, Johnstone, D, Calciu, CD, Block, P, Myers, MG, Chocron, S, Rouleau, JL, Faculteit Medische Wetenschappen/UMCG, and Cardiovascular Centre (CVC)

Subjects
REDUCTION, ENLARGEMENT TRIAL, CONGESTIVE-HEART-FAILURE, MYOCARDIAL-INFARCTION, ENALAPRIL, SURVIVAL, CAPTOPRIL, EJECTION FRACTIONS, CARDIOVASCULAR EVENTS, QUINAPRIL
Abstract

It has been hypothesized that angiotensin-converting enzyme (ACE) inhibition, independent from its effect on ventricular function and blood pressure, could affect the atherosclerotic process and reduce the incidence of ischemic events and its complications. Several large clinical outcome trials were designed to test this hypothesis: QUIET, HOPE, EUROPA, PEACE, and IMAGINE. The results of the PEACE study were recently reported, leaving the IMAGINE study as the last chapter in our efforts to evaluate the role of ACE inhibition in coronary artery disease with preserved left ventricular function. In this report, we compare these studies with respect to their methodology and patient population and analyze the unique nature of the last ongoing study, IMAGINE. The reported studies show that patients with coronary artery disease who are at low-to-moderate or high risk should receive an ACE inhibitor if tolerated. However, when the absolute risk of a patient decreases, and intensive contemporary management is given, with good control of risk factors, the absolute and perhaps relative benefits of an ACE inhibitor decrease and their routine use in these patients may not be warranted. The role of ACE inhibition started early post-coronary artery bypass graft in patients with preserved left ventricular function, and intensive contemporary management remains to be determined and should get answered by the IMAGINE study. Moreover, the IMAGINE population is not only a lower risk population than those enrolled in HOPE or EUROPA, but also the risk for this population is bimodal in nature (early post-revascularization inflammation and thrombosis vs long-term atherosclerosis progression) and may provide further insight into underlying mechanisms.

Published
2006

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