1. Early-onset Stroke in a Patient With Nasopharyngeal Cancer Associated With Protein C Deficiency
- Author
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Ya-Ning Chiu, Tyng-Guey Wang, and Chein-Wei Chang
- Subjects
carotid stenosis ,nasopharyngeal cancer ,protein C deficiency ,radiotherapy ,stroke ,Medicine (General) ,R5-920 - Abstract
We report a 47-year-old male stroke patient with nasopharyngeal cancer (NPC) and protein C deficiency. The patient was diagnosed with NPC and received a complete course of radiotherapy. Infarction stroke occurred 28 months after radiotherapy and magnetic resonance imaging of the brain confirmed the diagnosis. Carotid duplex sonography showed 50–79% stenosis in his left internal carotid artery. Coagulation profiles indicated protein C deficiency. After medical treatment and rehabilitation, the patient regained the ability to walk and he could perform most of his daily activities. Radiotherapy-induced carotid stenosis is an exacerbating feature of stroke in patients with protein C deficiency. We suggest early carotid duplex sonography and survey of the coagulation profile to prevent a stroke in patients with NPC.
- Published
- 2009
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