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Varied clinical patterns, physical activities, muscle enzymes, electromyographic and histologic findings in patients with post-polio syndrome in Taiwan
- Source :
- Spinal Cord. 39:526-531
- Publication Year :
- 2001
- Publisher :
- Springer Science and Business Media LLC, 2001.
-
Abstract
- Study design: A study of the clinical features, physical activity, muscle enzyme, electromyography and histopathological alternations of muscles in patients with post-polio syndrome (PPS). Objective: To assess the varied patterns of PPS in Taiwan. Setting: Taiwan. Methods: Thirty-one patients who fulfill the inclusion criteria of PPS were selected for study. Clinical features, physical activity scale, serum concentrations of creatine kinase, electromyography and histopathological alterations of muscles were assessed and correlated to the causes of PPS patients. Results: Patients with PPS in Taiwan are relatively young, with a mean age of 39.3 years. Elevated concentration of creatine kinase was found predominantly in male patients with higher physical activities. Electromyographic examinations as well as histological tests of affected muscles revealed prominent evidence of chronic and active denervation with reinnervation in PPS patients. Conclusion: Patients with PPS in Taiwan are young. Thus, PPS should not be attributed to aging. Physical attrition with degradation of nerve terminals is considered the main cause of this disease. Sponsorship: This study was supported by the National Science Council, Republic of China under grant no. NSC-83-0412-B002-302. Spinal Cord (2001) 39, 526–531.
- Subjects :
- Adult
Male
medicine.medical_specialty
education
Taiwan
Physical exercise
Electromyography
Central nervous system disease
Post-polio syndrome
Surveys and Questionnaires
Internal medicine
medicine
Humans
Muscle, Skeletal
Creatine Kinase
health care economics and organizations
Nerve Endings
Denervation
biology
medicine.diagnostic_test
business.industry
General Medicine
Middle Aged
medicine.disease
medicine.anatomical_structure
Neurology
Physical therapy
biology.protein
Female
Creatine kinase
Postpoliomyelitis Syndrome
Neurology (clinical)
business
Complication
Reinnervation
Subjects
Details
- ISSN :
- 14765624 and 13624393
- Volume :
- 39
- Database :
- OpenAIRE
- Journal :
- Spinal Cord
- Accession number :
- edsair.doi.dedup.....1668932380cf30d194ad6bec7618ef85