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157 results on '"Caroline Ospelt"'

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1. Explainable deep learning for disease activity prediction in chronic inflammatory joint diseases.

2. Molecular maps of synovial cells in inflammatory arthritis using an optimized synovial tissue dissociation protocol

3. The long non-coding RNA HOTAIR contributes to joint-specific gene expression in rheumatoid arthritis

4. The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels

5. Joint-level responses to tofacitinib and methotrexate: a post hoc analysis of data from ORAL Start

6. Site-specific assessment of spinal radiographic progression improves detection of TNF blocker-associated disease modification in axial spondyloarthritis: longitudinal observational data from the Swiss Clinical Quality Management Registry

8. BRD3 Regulates the Inflammatory and Stress Response in Rheumatoid Arthritis Synovial Fibroblasts

9. Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability

10. Gender equity in academic rheumatology, current status and potential for improvement: a cross-sectional study to inform an EULAR task force

12. Bromodomain Protein Inhibitors Reorganize the Chromatin of Synovial Fibroblasts

14. Nicotine Changes the microRNA Profile to Regulate the FOXO Memory Program of CD8+ T Cells in Rheumatoid Arthritis

15. Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis

16. The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts

17. Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions

18. Molecular Characterization of Human Lymph Node Stromal Cells During the Earliest Phases of Rheumatoid Arthritis

19. Epigenetic biomarkers in rheumatology – the future?

20. Expression and Regulation of PIWIL-Proteins and PIWI-Interacting RNAs in Rheumatoid Arthritis.

21. Site of invasion revisited: epigenetic drivers of joint destruction in RA

22. The long-non coding RNA HOTAIR as site specific regulator of inflammation in chronic arthritis

23. A brief history of epigenetics

24. Gender Equity in Academic Rheumatology, Current Status and Potential for Improvement: A Cross-Sectional Study to Inform an EULAR Task Force

25. A comprehensive single-cell atlas of freshly-dissociated human synovium in inflammatory arthritis with an optimized dissociation protocol for prospective fresh synovial biopsy collection

26. A comprehensive single-cell atlas of freshly dissociated human synovium in inflammatory arthritis with an optimized dissociation protocol for prospective fresh synovial biopsy collection

27. TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies

28. Coordinated glucocorticoid receptor and MAFB action induces tolerogenesis and epigenome remodeling in dendritic cells

29. Organ- and Site-Specific HOX Gene Expression in Stromal Cells

30. MAFB surrogates the glucocorticoid receptor ability to induce tolerogenesis in dendritic cells

31. Individual functions of the histone acetyl transferases CBP and p300 in regulating the inflammatory response of synovial fibroblasts

32. Location, location, location: how the tissue microenvironment affects inflammation in RA

33. Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability

34. Epigenetics, pregnancy and autoimmune rheumatic diseases

35. Role of synovial fibroblast subsets across synovial pathotypes in rheumatoid arthritis: a deconvolution analysis

36. CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17–Mediated Psoriasiform Skin Inflammation In Vivo

37. OP0016 IDENTIFICATION OF FUNCTIONAL VARIANTS IN THE RHEUMATOID ARTHRITIS ASSOCIATED JAZF1 LOCUS IN SYNOVIAL FIBROBLASTS

38. OP0020 HOMEOBOX D TRANSCRIPTION FACTORS SHAPE DIFFERENTIAL JOINT ENVIRONMENT BETWEEN ANTERIOR FINGER JOINTS AND THUMB

39. OP0074 A FRAMEWORK OF POTENTIAL INTERVENTIONS TO ACCELERATE GENDER-EQUITABLE CAREER ADVANCEMENT IN ACADEMIC RHEUMATOLOGY

40. Genomic Responses of Mouse Synovial Fibroblasts During Tumor Necrosis Factor-Driven Arthritogenesis Greatly Mimic Those in Human Rheumatoid Arthritis

41. Carbamylation of vimentin is inducible by smoking and represents an independent autoantigen in rheumatoid arthritis

42. THU0006 PROINFLAMMATORY RESPONSES IN THE JAK-STAT PATHWAY IN SYNOVIAL FIBROBLASTS ARE STIMULUS-SPECIFIC AND ONLY PARTIALLY INHIBITED BY THERAPEUTIC DOSES OF TOFACITINIB

43. SAT0055 JOINT SPECIFIC TNF RESPONSE OF SYNOVIAL FIBROBLASTS IN RHEUMATOID ARTHRITIS

44. OP0191 EPIGENETIC PROFILING OF SYNOVIAL FIBROBLASTS REVEALS STRUCTURAL DNA DYNAMICS AT DISEASE IMPLICATED CHROMOSOME REGIONS

45. FRI0513 HISTONE-ACETYLTRANSFERASES CBP AND P300 REGULATE AUTOPHAGY AND PROTEASOMAL DEGRADATION IN SYNOVIAL FIBROBLASTS

46. THU0038 INDIVIDUAL FUNCTIONS OF THE HISTONE-ACETYLTRANSFERASES CBP AND P300 IN REGULATING THE INFLAMMATORY RESPONSE OF RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLASTS

47. FRI0144 JOINT-SPECIFIC RESPONSES TO TOFACITINIB AND ADALIMUMAB IN RHEUMATOID ARTHRITIS: A POST HOC ANALYSIS OF DATA FROM ORAL STANDARD AND ORAL STRATEGY

48. OP0290 HOTAIR IS INVOLVED IN JOINT PATTERNING BY REGULATING FGFR2, BMP2 AND WNT PATHWAYS

49. Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts

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