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Developmental disabilities (DD) research has depended on volunteer and clinical samples, with limited racial/ethnic diversity. This study focused on improving diversity and retention in DD research. The sample included 225 parents with a child with DD and 4,002 parents without children with DD from diverse racial/ethnic groups, drawn from Midlife in the United States, a national longitudinal study. Unexpectedly, parents of children with DD from diverse racial/ethnic groups were more likely to participate longitudinally than other groups. Relative participant payment was a factor that enhanced their likelihood of retention. This research illustrates how large national studies can be leveraged to increase representativeness and ongoing participation of diverse racial/ethnic groups, especially in combination with other factors, such as parenting a child with DD.

Eudaimonic wellbeing emphasises the realisation of personal potential and being purposefully engaged. Prior findings on how eudaimonia varies by age, gender, race, and educational status are briefly noted, along with studies showing links to work and family life. With regard to health, different components of eudaimonia have been shown to predict longer lives, reduced risk for disease outcomes, and better physiological regulation. The enhancement of eudaimonic wellbeing has been the focus of intervention efforts. Against this backdrop, three directions for future research are presented. The first focuses on widening socioeconomic inequalities, which have been exacerbated by the worldwide COVID-19 pandemic. These historical changes are undermining the wellbeing of many, although more science and public policy action are needed. The second, more hopeful topic examines the role of the arts and humanities as beneficial influences on eudaimonia. The final topic focuses specifically on encounters with nature, via poetry, literature, the visual arts, and music, as factors that may nurture eudaimonia. The overall intent is to expand the reach of a theoretically and philosophically rich conception of human wellbeing.

Evidence of cultural differences in relationships and emotions has accumulated over the past few decades. As findings on cultural differences in psychological processes have accumulated, there has been growing interest in investigating whether they have implications for other phenomena such as health. Using scientific advances from the MIDUS and MIDJA studies, both publicly available, we examine links between culture and health. We first briefly review the accumulated evidence on cultural influences on health correlates of psychosocial factors. We then feature two recent developments – a more micro-level perspective on biological factors that may be involved in the culture and health linkage, and a more macro-level view of socioeconomic inequality, which also matters for health. Both perspectives inform the pathways through which health effects occur. Finally, we conclude our review by highlighting the changing historical contexts surrounding these cross-cultural investigations. Specifically, we draw attention to widening of economic inequality across cultures and the world-wide COVID-19 pandemic. These happenings bring notable implications for future research on health across cultural contexts.

Purpose The purpose of this article is to examine synergies between a eudaimonic model of psychological well-being (Ryff, 1989) and mental health practice. The model grew out of clinical, developmental, existential and humanistic perspectives that emphasized psychological strengths and capacities, in contrast to the focus on emotional distress and dysfunction in clinical psychology. Design/methodology/approach Conceptual foundations of the eudaimonic approach are described, along with the six components positive functioning that are used to measure well-being. These qualities may be important in facilitating the recovery experiences, which are of interest in Mental Health and Social Inclusion. Findings Four categories of empirical evidence about eudaimonia are reviewed: how it changes with aging, how it matters for health, what are its biological and neurological underpinnings and whether it can be promoted. Major contemporary forces against eudaimonia are also considered, including ever-widening inequality, the enduring pandemic and world-wide strife. In contrast, encounters with the arts and nature are put forth as forces for eudaimonia. The relevance of these ideas for mental health research and practice is considered. Practical implications Enormous suffering defines our contemporary world. Such realities call for greater attention to factors that undermine as well as nurture the realization of human potential, the core of eudaimonic well-being. Originality/value Mental health is often defined as the absence of mental illness. The novelty of the eudaimonic approach is to define mental health as the presence of well-being, assessed with different components of positive functioning.

Eudaimonic well-being builds on the writings of Aristotle and integrates contemporary theories of positive psychological functioning. The empirically operationalization is detailed, emphasizing the importance of rigorous psychometric evaluation. Scientific advances of this model of well-being are noted, showing links to sociodemographic factors, experiences in work and family life, and health outcomes. Three future directions for research are considered. The first addresses growing problems of socioeconomic inequality and their role in undermining the opportunities of disadvantaged segments of society to experience eudaimonia. These problems have now been exacerbated by the COVID-19 pandemic, which has disproportionately impacted those who were already vulnerable. The second new direction examines the role of the arts and humanities as factors that nurture eudaimonic well-being. Whether the arts can activate needed compassion and caring among the privileged is also considered. The third new direction examines the intersection of entrepreneurial studies with eudaimonic well-being. Conventional conceptions of entrepreneurial success focus on business profits; a case is made that eudaimonia, of the entrepreneur as well as his/her employees and surrounding communities, constitute further measure of success that elevate issues of virtue, morality, and ethics.

Evidence of cultural differences in relationships and emotions has accumulated over the past few decades. As findings on cultural differences in psychological processes have increased, there has been growing interest in investigating whether they have implications for other phenomena, such as health. Using scientific advances from the MIDUS and MIDJA studies, both publicly available, we examine links between culture and health. First, there is a brief review of the accumulated evidence on cultural influences on health correlates concerning psychosocial factors. We then feature two recent developments: a more micro‐level perspective regarding biological factors that may be involved in the culture and health linkage, and a more macro‐level view of socioeconomic inequality, which also concerns health. Both perspectives inform the pathways through which health effects become manifest. Finally, we conclude our review by highlighting the changing historical contexts within which these cross‐cultural investigations occur. Specifically, we draw attention to the widening of economic inequality across cultures and the world‐wide COVID‐19 pandemic. These instances bring notable implications for future research on health across cultural contexts. [ABSTRACT FROM AUTHOR] Copyright of Japanese Psychological Research is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The objective of this study was to examine whether experiences of discrimination have increased during the pandemic, particularly among negatively stigmatized racial/ethnic groups, and whether such experiences have exacerbated feelings of social isolation.Discrimination and social isolation were assessed before and during the pandemic in a sample of 263 Black and White young adults attending a large, predominantly White 4-year research university in the Southeastern region of the United States (52% Black, 48% White, 53% female, mean age = 19.2).Increases in discrimination were evident among Black but not White participants. Black participants also reported greater increases in social isolation than White participants, and changes in discrimination partially mediated the emergent racial disparity in social isolation.Findings are consistent with theoretical perspectives on discrimination during times of stress and suggest the need for broader attention to the impact of the pandemic on unfair treatment of stigmatized groups. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Objectives: This study describes a major effort to reinstate dropouts from the MIDUS longitudinal study and compare baseline characteristics among subgroups of participants to better understand predictors of retention, attrition, and reinstatement. Methods: All living dropouts were contacted, and 651 reinstated participants were interviewed in person (31.4% response rate). Age, gender, education, marital status, parental status, and physical and mental health were compared among the following groups: longitudinal sample, reinstated sample, those fielded for reinstatement who did not return, and those who dropped out at the 2nd or 3rd wave. Results: Multivariate analyses revealed that reinstated participants were younger, male, unmarried, and less educated and had children at baseline compared to longitudinal participants. Reinstatement was unsuccessful among those with poorer mental health at baseline compared to longitudinal participants. Discussion: This study informs reinstatement efforts, adjustment for attrition bias, and use of post-baseline data to examine aging consequents of early life vulnerability.

As a self-organizing act, entrepreneurship is a significant feature of and force within modern life that is intimately related to individuals’ growth, development, and well-being. We present a dynamic perspective on entrepreneurship and eudaimonic well-being, anchored in philosophical and psychological views on the essence of well-being as well as the essence of entrepreneurship as a value-driven form of agency. Drawing on the action-phase model, which we adapt to the venture creation phases of deliberation, planning, implementation, and reflection, key propositions are developed regarding how, and under what conditions, core aspects of psychological well-being come into play along the enterprising process.

AIM: To compare the prevalence of poor glycemic control in probability samples of Japanese and American adults, and to determine the association with their somatic phenotypes. MATERIAL AND METHODS: Blood samples and anthropometric measures were obtained from 382 Japanese, 32–79 years of age, randomly selected to reflect the 23 wards of Tokyo. HA1c values were compared to 1215 Americans, 35–86 years of age, from a national study across the 48 continental states, along with an over-sampling of African-Americans from one city (www.midus.wisc.edu). Body Mass Index (BMI) and Waist-hip ratio (WHR) were also assessed. RESULTS: Many Japanese now have high HA1c approaching Caucasian-American levels, although elevated HA1c (>6.5%, 48 mmol/mol) is not nearly as prevalent as among African-Americans. Significant age-related trends were evident in both countries, with poor glycemic control occurring at younger ages in males and rarely found until old age in Japanese women. Japanese had higher HA1c levels at BMIs of 23–25, in contrast to Americans with Type 2 diabetes who more typically had a BMI over 30. Central adiposity predicted HA1c levels better than BMI, a relationship also apparent at a smaller WHR in Japan. CONCLUSION: The prevalence of high HA1c in Tokyo almost rivals white Americans, but those statistics are dwarfed by the 37% of Afr-Amer adults identified with Type 2 diabetes. Elevated HA1c was more common in men, reflecting central adiposity, but poor glycemic control was also widespread among overweight Afr-Amer women. Type 2 diabetes was higher among older Japanese, when more women succumb. Overall, the findings highlight the societal and clinical challenges posed by demographic trends in both countries.

Understanding the changing health consequences of childhood socioeconomic disadvantage (SED) is highly relevant to policy debates on inequality and national and state goals to improve population health. However, changes in the strength of association between childhood SED and adult health over historic time are largely unexamined in the United States. The present study begins to address this knowledge gap. Data were from 2 national samples of adults collected in 1995 (n = 7,108) and 2012 (n = 3,577) as part of the Midlife in the United States study. Three measures of childhood SED (parents’ occupational prestige, childhood poverty exposure, and parents’ education) were combined into an aggregate index and examined separately. The association between childhood SED (aggregate index) and 5 health outcomes (body mass index, waist circumference, chronic conditions, functional limitations, and self-rated health) was stronger in the 2012 sample than the 1995 sample, with the magnitude of associations being approximately twice as large in the more recent sample. Results persisted after adjusting for age, sex, race, marital status, and number of children, and were similar across all 3 measures of childhood SED. The findings suggest that the socioeconomic circumstances of childhood might have become a stronger predictor of adult health in recent decades.

Subjective measures of well-being are increasingly seen by scholars and policy makers as valuable tools to assess quality of life. Hedonic accounts focus on people’s experience of life in positive ways while eudaimonic accounts are concerned with realization of personal potential. However, to what extent do an “enjoyable” and a “flourishing” life overlap? Using an innovative clustering-and-projection technique (Self-Organized Map), the joint distributional patterns of multiple hedonic and eudaimonic well-being indicators were examined in a nationally representative longitudinal study of US adults (MIDUS). Results show that the two accounts largely converged with about 70% of the sample observations registering high/low scores in both well-being dimensions. However, the remaining 30% of respondents experienced divergent well-being levels. Association between these combined profiles and a series of socio-demographic characteristics and social stratification factors were investigated. Findings showed that chances of uniformly high well-being increase with age, while higher income, educational level, marriage, and being a female are linked to lesser probabilities of experiencing joint low well-being patterns. Experiencing a combination of high hedonic/low eudaimonic well-being was more frequent for less educated individuals, and men. Finally, the persistence over time of these combined well-being profiles was more frequent in case of convergent hedonic/eudaimonic levels. For divergent patterns we revealed substantial changes over a 10-year period with respondents registering low hedonic/high eudaimonic well-being at time t having greater chances of upward movement toward improved well-being compared to individuals who experienced high hedonic/low eudaimonic levels in the first time period.

OBJECTIVE The current study examined race differences in how childhood socioeconomic status (SES) predicted midlife inflammation. It also tested psychological resources (purpose in life, optimism, and conscientiousness) as moderators of the association between childhood SES and inflammation among Black and White adults. METHOD Data came from the biomarker subsamples of the Midlife in the United States Core and Refresher studies (n = 1,578 White and n = 395 Black participants). Childhood SES was operationalized as a composite of parental education, perceived financial status, and welfare status. Outcomes included circulating IL-6 and CRP. RESULTS Childhood SES did not predict IL-6 or CRP among Black or White adults in fully adjusted models. Among Black adults with low optimism, lower childhood SES predicted higher IL-6 and CRP. Among Black adults with low purpose in life, lower childhood SES predicted higher CRP (but not IL-6). Conscientiousness did not moderate childhood SES-inflammation associations among Black adults. Among White adults with low conscientiousness or low optimism, lower childhood SES predicted higher IL-6 (but not CRP). Purpose in life did not moderate associations among White adults. Effect sizes were small (≤1% variance explained) and comparable to effects of clinical risk factors in this sample (e.g., age, chronic conditions). CONCLUSIONS Race differences in the childhood SES and inflammation association were not apparent. Childhood SES was linked to inflammation more strongly among those with fewer psychological resources across both racial groups. Psychological resources may be important moderators of inflammation in the context of early life SES disadvantage. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Functional limitations—difficulty in carrying out activities of daily living—have been linked to poorer well-being in Western cultures. This might be partly due to the lower personal control associated with functional limitations. However, compared with the West, in Asian cultural contexts (e.g., Japan) where agency and control are based less predominantly on individual attributes, the link between functional limitations and well-being may be weaker. Using cross-sectional probability samples from the United States and Japan (Study 1), functional limitations were associated with lower well-being in both cultures, though the association was weaker in Japan than in the United States and personal control played a mediating role. Furthermore, analyses of longitudinal data (Study 2) showed the cross-cultural patterns generally consistent with the cross-sectional analyses of Study 1, though the cultural moderation was found for fewer well-being measures. Such findings enrich our understanding of how health status and well-being are related across cultures.

Purpose: Growing evidence indicates that a higher sense of purpose in life ( purpose) is associated with reduced risk of chronic diseases and mortality. However, epidemiological studies have not evaluated if change in purpose is associated with subsequent health and well-being outcomes. Design: We evaluated if positive change in purpose (between t0; 2006/2008 and t1;2010/2012) was associated with better outcomes on 35 indicators of physical health, health behaviors, and psychosocial well-being (at t2;2014/2016). Sample: We used data from 12,998 participants in the Health and Retirement study—a prospective and nationally representative cohort of U.S. adults aged >50. Analysis: We conducted multiple linear-, logistic-, and generalized linear regressions. Results: Over the 4-year follow-up period, people with the highest (versus lowest) purpose had better subsequent physical health outcomes (e.g., 46% reduced risk of mortality (95% CI [0.44, 0.66])), health behaviors (e.g., 13% reduced risk of sleep problems (95% CI [0.77, 0.99])), and psychosocial outcomes (e.g., higher optimism (β = 0.41, 95% CI [0.35, 0.47]), 43% reduced risk of depression (95% CI [0.46, 0.69]), lower loneliness (β = −0.35, 95% CI [−0.41, −0.29])). Importantly, however, purpose was not associated with other physical health outcomes, health behaviors, and social factors. Conclusion: With further research, these results suggest that sense of purpose might be a valuable target for innovative policy and intervention work aimed at improving health and well-being.

Subjective measures of well-being are increasingly seen by scholars and policy makers as valuable tools to assess quality of life. Hedonic accounts focus on people’s experience of life in positive ways while eudaimonic accounts are concerned with realization of personal potential. However, to what extent do an “enjoyable” and a “flourishing” life overlap? Using an innovative clustering-and-projection technique (Self-Organized Map), the joint distributional patterns of multiple hedonic and eudaimonic well-being indicators were examined in a nationally representative longitudinal study of US adults (MIDUS). Results show that the two accounts largely converged with about 70% of the sample observations registering high/low scores in both well-being dimensions. However, the remaining 30% of respondents experienced divergent well-being levels. Association between these combined profiles and a series of socio-demographic characteristics and social stratification factors were investigated. Findings showed that chances of uniformly high well-being increase with age, while higher income, educational level, marriage, and being a female are linked to lesser probabilities of experiencing joint low well-being patterns. Experiencing a combination of high hedonic / low eudaimonic well-being was more frequent for less educated individuals, and men. Finally, the persistence over time of these combined well-being profiles was more frequent in case of convergent hedonic/eudaimonic levels. For divergent patterns we revealed substantial changes over a 10-year period with respondents registering low hedonic / high eudaimonic well-being at time t having greater chances of upward movement toward improved well-being compared to individuals who experienced high hedonic / low eudaimonic levels in the first time period.

Social inequalities in health and their early-life origins have been extensively documented. Although the complex direct and intermediate mechanisms linking early-life disadvantage to later health are not yet fully understood, new findings on biological markers distinctly related with early-life experiences suggest a causal relationship. In this issue, Fuller-Rowell et al. (Am J Epidemiol. 2021:190(11):2284-2293) step back to examine the role of childhood disadvantage in the United States in different periods, observing that the relationship with later health seems to have strengthened over time. The main explanation the authors bring up has to do with increased income segregation and changes in labor market composition that limit opportunities for persons with low educational attainment. In other words, while the rich get richer, the poor get poorer, the middle class shrinks, and there are fewer interactions across different socioeconomic groups and the social ladder is blocked. Other evidence suggests that investments in children, through early education and academic support programs, could help reduce the consequences of childhood disadvantage on long-term health.

This chapter provides an overview of hedonic and eudaimonic approaches to well-being, both with roots traceable to the ancient Greeks. The authors examine the history of each approach and describe scientific endeavors seeking to translate the ideas to empirical assessment tools. They review how these two varieties of well-being are distributed in the general population by attending to their associations with major demographic factors (age, socioeconomic status, gender, race) as well as the interplay (intersectionality) of such factors. Such information contextualizes what is known about who reports they are or are not experiencing various aspects of well-being. The authors then examine how hedonic and eudaimonic well-being are linked with multiple indicators of health (self-reported, morbidity, mortality, biological systems). There is a paucity of studies that have jointly examined both types of well-being. The authors then draw attention to changing historical conditions and what this means for the future study of well-being and health.

We question use of the term “well-being” to encompass notably distinct phenomena (objective indicators of socioeconomic status and health, subjective indicators of psychological experience) and dispute characterization of the field of well-being as relatively new. We also call for greater interplay between government surveys and multiuse cohort studies, both of which increasingly focus on well-being. The MIDUS study is presented as an example of how to negotiate distinct disciplinary priorities in broad-based studies of well-being and health, including those that take context seriously. We conclude with explanations for why we do not endorse any of the measurement recommendations (single-item measures, 4- to 6-item measures, multi-item assessments) put forth in the preceding chapter, arguing that the ultra-short assessments ignore extensive prior science documenting the complex, multifaceted nature of well-being, while the proposed longer assessment (Comprehensive Inventory of Thriving) suffers from multiple problems including a questionable conceptual foundation, inadequate evidence of validity and reliability, and highly redundant items.

We challenge the view that “one is better than none” on grounds that single-item assessments perpetuate a simplistic view of well-being, which is out of touch with how the field has progressed over recent decades. We also question blanket advocacy for measures in the absence of substantive scientific questions that require thoughtful engagement with the prior literature to make sound measurement choices. Substantive illustrations, invoking research on well-being and health in different cultural and socioeconomic contexts, are provided. Quality control is also essential in making sound measurement choices. Numerous contenders fail at this juncture because they have no conceptual foundation and also lack rigorous psychometric analyses documenting their empirical credibility. Another critical element in adjudicating measurement quality is extent of prior usage: evidence that the measures have taken hold in the scientific community, indicated by citation counts and number of published studies. We conclude that all such quality control criteria were inadequately addressed or missing in the measurement recommendations put forth in Chapter 17.

The impression is that negative events multiply as one grows older and inevitably lead to loneliness, isolation, and unhappiness. Although the self-system model proposes that prior health status sets the stage for social comparison processes, which then interact with health profiles in accounting for change in psychological well-being, there are other possible relationships to consider. As predicted in the self-system model, physical health had direct effects on psychological well-being for these individuals with cancer. A somewhat different pattern emerged in relation to psychological distress or depression similar to findings regarding the self-system model described earlier. The self-system model proposes three aspects of the self that encompass interpersonal, intrapersonal, and social structural processes involved in the formation of the self-concept. There are, however, broad social-structural variables that potentially influence each piece of the self-system model and add to the explanation of psychological well-being.

Objectives: Eudaimonic well-being (EWB), increasingly recognized as a critical component of health, typically declines in later life, and there are no existing programs to sustain or increase EWB in older adults. Lighten UP! is an 8-week program to promote EWB through facilitated group sessions in community settings and at-home practice. Building on earlier pilot research, the current study assessed the effect of the Lighten UP! Program using a longitudinal, multi-site design. Methods: Men and women (N=169) aged 60 and over were recruited from three Wisconsin communities. EWB, life satisfaction, depression, and diverse aspects of health were assessed before and after the program and at 6-month follow up. Results: Participants reported significantly increased EWB; these changes were maintained 6months later. The specific EWB domains of self-acceptance, positive relations, and personal growth showed the most robust gains. Participants also showed significant and sustained declines in depressive symptoms, anxiety, and hostility. Conclusions: Lighten UP! Program confirmed its positive effects for enhancing EWB in older adults living in multiple community settings. Clinical Implications: Programs that sustain or enhance EWB in older adults can be expected to yield improvements in diverse aspects of mental and physical health.

Neural dynamics in response to affective stimuli are linked to momentary emotional experiences. The amygdala, in particular, is involved in subjective emotional experience and assigning value to neutral stimuli. Because amygdala activity persistence following aversive events varies across individuals, some may evaluate subsequent neutral stimuli more negatively than others. This may lead to more frequent and long-lasting momentary emotional experiences, which may also be linked to self-evaluative measures of psychological well-being (PWB). Despite extant links between daily affect and PWB, few studies have directly explored the links between amygdala persistence, daily affective experience, and PWB. To that end, we examined data from 52 human adults (67% female) in the Midlife in the United States study who completed measures of PWB, daily affect, and functional MRI (fMRI). During fMRI, participants viewed affective images followed by a neutral facial expression, permitting quantification of individual differences in the similarity of amygdala representations of affective stimuli and neutral facial expressions that follow. Using representational similarity analysis, neural persistence following aversive stimuli was operationalized as similarity between the amygdala activation patterns while encoding negative images and the neutral facial expressions shown afterward. Individuals demonstrating less persistent activation patterns in the left amygdala to aversive stimuli reported more positive and less negative affect in daily life. Further, daily positive affect served as an indirect link between left amygdala persistence and PWB. These results clarify important connections between individual differences in brain function, daily experiences of affect, and well-being.SIGNIFICANCE STATEMENTAt the intersection of affective neuroscience and psychology, researchers have aimed to understand how individual differences in the neural processing of affective events map onto to real-world emotional experiences and evaluations of well-being. Using a longitudinal dataset from 52 adults in the Midlife in the United States (MIDUS) study, we provide an integrative model of affective functioning: less amygdala persistence following negative images predicts greater positive affect (PA) in daily life, which in turn predicts greater psychological well-being (PWB) seven years later. Thus, day-to-day experiences of PA comprise a promising intermediate step that links individual differences in neural dynamics to complex judgements of PWB.

Chile is currently experiencing a progressive epidemiological transition towards chronic diseases. In this country, >50% of annual deaths are attributed to cardiovascular disease and cancer. Moreover, health surveys have shown high prevalence of obesity, diabetes, hypertension, and elevated cardiovascular disease risk. In addition, mental health issues are also frequent among Chilean adults. On the other hand, the agri-food system contributes to 21–37% of greenhouse gases emissions worldwide. Overall, current health and food chain situation calls out for design and implementation of evidence-based feasible and effective nutritional interventions needed to promote physical and mental health along with addressing food sustainability in Chile. Nowadays, the Mediterranean diet is recognized as one of the healthiest dietary patterns based on observational and interventional studies linked to a wide variety of health outcomes. However, a Mediterranean lifestyle goes well beyond food intake: it includes promotion of psychosocial resources, community life as well as cultural traditions. Indeed, Mediterranean lifestyle is a true modus vivendi that integrally promotes physical, mental, and social well-being. In addition, the Mediterranean diet stands out for its environmental sustainability because it is characterized mainly as a plant-based dietary pattern with low carbon and water footprints. Remarkably, Central Chile has a Mediterranean-like setting with plant and animal food production and availability patterns comparable to those present in countries located around the Mediterranean Sea. Therefore, this article reviews how promotion of Mediterranean lifestyle adherence in Chile offers great potential for management of the ongoing epidemiological transition to chronic diseases as well to promote psychological well-being within a unique food system and dietary sustainability vision for this Latin American country.

Objective In the United States, 28.6 million people used illicit drugs or misused prescription drugs in the last 30 days. Thus, identifying factors linked with lower likelihood of future drug misuse is an important target for research and practice. Sense of purpose in life has been linked with better behavioral and physical health outcomes. Furthermore, a higher sense of purpose may reduce the likelihood of drug misuse because it has been linked with several protective factors including enhanced ability to handle stress, higher pain tolerance, and lower impulsivity. However, the association between sense of purpose and drug misuse has been understudied. Thus, we tested whether people with a higher sense of purpose at baseline had a lower likelihood of future drug misuse 9 to 10 years later. Methods This study included 3535 middle-aged adults from the Midlife in the United States Study who were not misusing drugs at baseline. Using multiple logistic regression models, we assessed whether baseline purpose in life was associated with risk of misusing drugs 9 to 10 years later. Results Among respondents not misusing drugs at baseline, people in the highest quartile of purpose (versus lowest quartile) had a substantially lower likelihood of future drug misuse in a model adjusting for demographic variables (odds ratio = 0.50, 95% confidence interval = 0.31-0.83). Associations remained evident after additionally adjusting for psychological distress, baseline health, and health behaviors. Conclusions A growing knowledge base suggests that a sense of purpose can be increased. Additional research is needed to evaluate sense of purpose as a novel target in the prevention and reduction of drug misuse.

Background The aim of this study was to examine the internal consistency, structural validity, and convergent/known-group validity of the Japanese version of the 42-item Psychological Well-Being Scale (PWBS-42). Methods The PWBS-42 includes six 7-item subscales designed to measure the following dimensions of eudaimonic psychological well-being: 1) autonomy, 2) environmental mastery, 3) personal growth, 4) positive relations with others, 5) purpose in life, and 6) self-acceptance. A questionnaire was administered to 2102 community residents in Tokyo aged 30 or over as a part of the Midlife in Japan (MIDJA) survey, in 2008. The internal consistency reliability was tested using Cronbach’s α. Structural validity was examined using exploratory factor analysis (EFA). Convergent validity was evaluated by calculating correlations of the Japanese PWBS-42 subscales with life satisfaction, negative affect, negative adjectives, positive affect, positive adjectives, self-esteem, and perceived stress scales. Results Data from 1027 respondents (505 males and 522 females) were analyzed (valid response rate = 56.2%). Cronbach’s α values ranged from 0.70 to 0.78 for five of the subscales, while that for purpose in life was lower (0.57). EFA yielded a five-factor structure: The first two factors consisted of negative and positive items mostly from the environmental mastery, purpose in life, and self-acceptance subscales. The third, fourth, and fifth factors consisted mostly of items from the positive relations with others, autonomy, and personal growth subscales, respectively. As hypothesized, the scores for life satisfaction, negative and positive affect/adjectives, self-esteem and perceived stress were significantly correlated with all subscales of the Japanese PWBS-42. Conclusion The subscales of the Japanese version of the PWBS-42 showed accep. levels of reliability and support for convergent validity in the Japanese population. The factor structure was slightly different from the theoretical 6-factor model: items of three subscales (environmental mastery, purpose in life, and self-acceptance) loaded together on two factors. This finding may be interpreted in light of the interdependent self construal found in Japan in which these three components could be closely linked.

Emodiversity, or the variety and relative abundance of emotions experienced, provides a metric that can be used to understand emotional experience and its relation to well-being above and beyond average levels of positive and negative affect. Past research has found that more diverse emotional experiences, both positive and negative, are related to better mental and physical health outcomes. The present research aimed to test the relationship between positive and negative emodiversity across the span of 8 days with measures of health and well-being using 2 samples of the Midlife in the United States study (http://midus.wisc.edu/). Participants (N = 2,788) reported emotional states (14 negative, 13 positive) once each day for 8 days. Emodiversity scores were computed for each day using an adaptation of Shannon's biodiversity index and averaged across the days. All models included average affect and demographic covariates. Greater positive emodiversity was associated with fewer symptoms of depression and anxiety and fewer physical health symptoms but was not related to eudaimonic well-being nor cognitive functioning. In contrast to previous research, greater negative emodiversity was related to more symptoms of depression and anxiety and more physical health symptoms. Greater negative emodiversity was only associated with one positive outcome: better executive functioning. These findings illustrate inconsistencies across studies in whether negative emodiversity is associated with better or worse outcomes and raise further questions about how the construct of emodiversity can be better refined. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Japan is an exceptionally healthy East Asian country with extended longevity. In addition, the typical levels of several proinflammatory proteins, including both C-reactive protein (CRP) and interleukin-6 (IL-6), are often reported to be low when compared to American and European populations. This analysis determined if blood levels of CRP and IL-6 were associated with 4 cultural practices reflective of Japanese behavior and customs -- drinking tea, eating seafood, consuming vegetables, and partaking in relaxing baths regularly - among 382 adults living in Tokyo. Regression models controlled for demographic factors, adiposity (BMI), physical exercise, smoking, alcohol use, and chronic illness (e.g., diabetes). Consuming a Japanese diet was associated with significantly lower CRP and IL-6 levels. More frequent bathing was associated with lower IL-6, but not specifically predictive of low CRP. This study has confirmed prior evidence for low inflammatory activity in Japanese adults and its association with several behavioral practices common in Japan.

Empirical studies of purpose in life are flourishing. However, in light of a rapidly changing social milieu, there are pressing but understudied issues to address if purpose research is to realize its potential in impacting people’s lives. We first distill what has been learned from prior research on age variation in purpose in life and briefly review accumulating evidence linking higher levels of purpose to better physical health. Possible biobehavioral mechanisms underlying the purpose-health connection are noted. We then build upon this evidence to examine an array of factors that might undermine or nurture purposeful life engagement. Growing societal inequality may be critical in limiting people’s capacities to pursue meaningful lives, but more research is needed. Alternatively, growing research now links the arts and humanities to health. We focus on possible influences these realms might have in cultivating purpose. The role of education in nurturing exposure to the arts is examined, along with problems of elitism in higher education (thereby re-invoking themes of inequality). Our final section calls for research that more explicitly links purpose in life to human virtues and values. Theoretical approaches and tractable empirical topics are delineated. Our overall objective is to offer innovative future paths to deepen understanding of how health and well-being at individual and societal levels are tied to purpose in life.

Objective Prediabetes and type 2 diabetes (i.e., hyperglycemia) are characterized by insulin resistance. These problems with energy metabolism may exacerbate emotional reactivity to negatively valenced stimuli and related phenomena such as predisposition toward negative affect, as well as cognitive deficits. Higher emotional reactivity is seen with hyperglycemia and insulin resistance. However, it is largely unknown how metabolic dysfunction correlates with related neural, hormonal, and cognitive outcomes. Methods Among 331 adults from the Midlife in the United States study, eye-blink response (EBR) we cross sectionally examined to gauge reactivity to negative, positive, or neutrally valenced pictures from international affect picture system stimuli proximal to an acoustic startle probe. Increased EBR to negative stimuli was considered an index of stress reactivity. Frontal alpha asymmetry, a biomarker of negative affect predisposition, was determined using resting electroencephalography. Baseline urinary cortisol output was collected. Cognitive performance was gauged using the Brief Test of Adult Cognition by telephone. Fasting glucose and insulin characterized hyperglycemia or the homeostatic model assessment of insulin resistance. Results Higher homeostatic model assessment of insulin resistance corresponded to an increased startle response, measured by EBR magnitude, for negative versus positive stimuli (R = 0.218, F(1,457) = 5.48, p = .020, euglycemia: M(SD) = .092(.776), hyperglycemia: M(SD) = .120(.881)). Participants with hyperglycemia versus euglycemia showed greater right frontal alpha asymmetry (F(1,307) = 6.62, p = .011, euglycemia: M(SD) = .018(.167), hyperglycemia: M(SD) = -.029(.160)), and worse Brief Test of Adult Cognition by telephone arithmetic performance (F(1,284) = 4.25, p = .040, euglycemia: M(SD) = 2.390(1.526), hyperglycemia: M(SD) = 1.920(1.462)). Baseline urinary cortisol (log10 μg/12 hours) was also dysregulated in individuals with hyperglycemia (F(1,324) = 5.09, p = .025, euglycemia: M(SD) = 1.052 ± .332, hyperglycemia: M(SD) = .961 (.362)). Conclusions These results suggest that dysmetabolism is associated with increased emotional reactivity, predisposition toward negative affect, and specific cognitive deficits.

OBJECTIVE Foundational theoretical perspectives suggest that socioeconomic disadvantage (SED) increases an individual's risk of being exposed to unfair treatment or discrimination. However, little empirical attention has been given to the role of perceived discrimination in the SED-health gradient. Addressing this knowledge gap, the current study examined the mediating role of discrimination in the longitudinal association between SED and self-rated health. METHOD Participants in the Midlife in the United States (MIDUS) study were followed over 3 waves covering a 17- to 19-year period (N = 6,286; 53% female; 91% White; mean age at baseline = 47 years, SD = 13). SED was assessed from education, occupational prestige, income, and assets; self-rated health was measured at baseline and follow-up assessments. Two measures of discrimination-perceived inequality in work and everyday discrimination-were considered as mediators. RESULTS Both measures of discrimination emerged as important explanatory variables in the link between SED and health. SED at the baseline assessment was associated with changes in self-rated health over the 17- to 19-year period (B = -.15, p < .001). Measures of discrimination partially mediated this longitudinal association, explaining 22% of the total effect. Exposure to discrimination and its health consequences were also more pronounced at younger ages. CONCLUSION Additional research is needed to replicate the findings of this study using objective health measures and to examine possible interventions. Challenging the ideologies and practices that underlie social class-related discrimination, or mitigating its harmful consequences, will both be important approaches to consider. (PsycINFO Database Record

This essay examines core contributions of a model of psychological well-being that has had widespread scientific impact. It drew on distant formulations to identify new dimensions and measures for assessing what it means to be well. Key themes among the more than 750 studies using the model are sketched, followed by reflections about why there has been so much interest in this eudaimonic approach to well-being. A final section looks to the future, proposing new directions to illuminate the forces that work against the realization of human potential as well as those that nurture human flourishing and self-realization.