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Sixty-two centres in 16 countries contributed with 2,694 open fractures cases to an international, multi-centric, retrospective cohort study involving different healthcare settings. The INTELLECT study results show that there are significant disparities on the management of open lower limb fractures internationally. A timely, multidisciplinary, guideline-directed care is a protective factor for developing infective complications, non-union and requiring an amputation.

In the framework of the ADAMO Project (Analysis Technologies, DiAgnostics and Monitoring for the Conservation and Restoration of Cultural Heritage), a measurement campaign was carried out by different diagnostic techniques for assessing the content and distribution of moisture in the lower part of the apse of the church of San Nicola in Carcere in Rome.

Nell'ambito del Progetto ADAMO (Tecnologie di Analisi, DiAgnostica e MOnitoraggio per la conservazione e il restauro di beni culturali), si è svolta una campagna di misure con diverse tecniche diagnostiche per la valutazione del contenuto e della distribuzione dell'umidità nella parte bassa dell'abside della chiesa di San Nicola in Carcere a Roma. L'approccio multidisciplinare è stato condotto con la termografia ad infrarossi, Risonanza Magnetica portatile, Indagini in situ mediante immagini acustiche, Indagini con prove soniche e ultrasoniche sulla muratura , termografia sonica e diagnostica remota mediante fluorescenza indotta da laser su porzioni dei muri absidali .

In this study a multi-analytical approach has been performed to characterise the constitutive materials of an ancient painted barkcloth or Tapa. Originating from Wallis Island, Polynesia, this cloth likely served utilitarian or ceremonial purposes and is part of the Felice Junck collection at the Pigorini, Muciv museum of Rome. During a recent conservation project, some micro-samples were taken from the support, brown and black painted areas and were investigated using the complementarity of SEM-EDX, FT-IR, Raman/SERS and solid-state C NMR and H HR-MAS spectroscopy. The combination of these techniques allowed the chemical characterization of the constitutive materials, from distinguishing the lignin and cellulose content of the support to the use of organic materials including condensed tannins (catechin, anthocyanidins, alkaloids), phlobaphene and vegetal anthraquinone based Morinda genus dyes for the decorations. A primary focus was placed on an understanding of its state of conservation where data of alteration products collected, namely metal carboxylates and oxalates can serve to formulate apt restoration efforts for this specific artefact.

This is a paper "Preparation of Lignin Nanoparticles from Wood Waste for Wood Surface Treatment" published in Nanomaterials Volume 9, 17 february 2019, page 281. https://doi.org/10.3390/nano9020281

The 'Catalogna' chicory ( Cichorium intybus L.) is a typical Italian vegetable cultivated for leaves and stems ('puntarelle'); these latter are novel foods, consumed as fresh or processed, and rapidly moving to global markets. The holistic characterization of stems was carried - out by combining NMR metabolic and RNAseq profiling of 'Galatina' (Gal) and 'Molfettese' (Mol) landraces, grown in Apulia and Lazio, in order to investigat e on the nutritional quality and performance in ex situ cultivation. The content variation of thirty - two compounds was affected by the genotype (G), environment (E) and GxE interaction; PCA explained over 90% of variation, and PC1 and PC2 components neatly discriminated Gal vs Mol based on growth sites and genotypes, respectively. Focusing on carbohydrates and amino acids, the total amount of the former was higher in Gal than Mol in both areas (consistently with predicted sweetness and sensory test), whilst the opposite trend occurred for total amino acid content. The Mol vs Gal gene differential transcription was performed based on a Gal reference transcriptome ; G, E, and GxE effects were found and KEGG analysis showed the enrichment of differentially expre ssed genes within the sucrose and phenylalanine metabolisms, consistently with the metabolic profile variations. Pearson's correlation analyses of gene expression vs metabolite amount variations allowed the selection of gene sets that could explain sugar a nd amino acid content differences between Gal and Mol stems. Overall, these analyses widened knowledge on the pathways that influence nutritive quality traits and pointed at target genes useful for plant breeding.