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5,014 results on '"Cao, F."'

1. Claudin 18.2 expression in digestive neuroendocrine neoplasms: a clinicopathological study

Author: Jiang, K., Cao, F., Yin, L., Hu, Y., Zhao, X., Huang, X., Ma, X., Li, J., Lu, M., and Sun, Y.
Published: 2024
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2. SN 2023ixf in Messier 101: Photo-ionization of Dense, Close-in Circumstellar Material in a Nearby Type II Supernova

Author: Jacobson-Galan, W. V., Dessart, L., Margutti, R., Chornock, R., Foley, R. J., Kilpatrick, C. D., Jones, D. O., Taggart, K., Angus, C. R., Bhattacharjee, S., Braff, L. A., Brethauer, D., Burgasser, A. J., Cao, F., Carlile, C. M., Chambers, K. C., Coulter, D. A., Dominguez-Ruiz, E., Dickinson, C. B., de Boer, T., Gagliano, A., Gall, C., Gao, H., Gates, E. L., Gomez, S., Guolo, M., Halford, M. R. J., Hjorth, J., Huber, M. E., Johnson, M. N., Karpoor, P. R., Laskar, T., LeBaron, N, Li, Z., Lin, Y., Loch, S. D., Lynam, P. D., Magnier, E. A., Maloney, P., Matthews, D. J., McDonald, M., Miao, H. -Y., Milisavljevic, D., Pan, Y. -C., Pradyumna, S., Ransome, C. L., Rees, J. M., Rest, A., Rojas-Bravo, C., Sandford, N. R., Ascencio, L. Sandoval, Sanjaripour, S., Savino, A., Sears, H., Sharei, N., Smartt, S. J., Softich, E. R., Theissen, C. A., Tinyanont, S., Tohfa, H., Villar, V. A., Wang, Q., Wainscoat, R. J., Westerling, A. L., Wiston, E., Wozniak, M. A., Yadavalli, S. K., and Zenati, Y.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Astrophysics of Galaxies, Astrophysics - Solar and Stellar Astrophysics
Abstract: We present UV/optical observations and models of supernova (SN) 2023ixf, a type II SN located in Messier 101 at 6.9 Mpc. Early-time ("flash") spectroscopy of SN 2023ixf, obtained primarily at Lick Observatory, reveals emission lines of H I, He I/II, C IV, and N III/IV/V with a narrow core and broad, symmetric wings arising from the photo-ionization of dense, close-in circumstellar material (CSM) located around the progenitor star prior to shock breakout. These electron-scattering broadened line profiles persist for $\sim$8 days with respect to first light, at which time Doppler broadened features from the fastest SN ejecta form, suggesting a reduction in CSM density at $r \gtrsim 10^{15}$ cm. The early-time light curve of SN2023ixf shows peak absolute magnitudes (e.g., $M_{u} = -18.6$ mag, $M_{g} = -18.4$ mag) that are $\gtrsim 2$ mag brighter than typical type II supernovae, this photometric boost also being consistent with the shock power supplied from CSM interaction. Comparison of SN 2023ixf to a grid of light curve and multi-epoch spectral models from the non-LTE radiative transfer code CMFGEN and the radiation-hydrodynamics code HERACLES suggests dense, solar-metallicity, CSM confined to $r = (0.5-1) \times 10^{15}$ cm and a progenitor mass-loss rate of $\dot{M} = 10^{-2}$ M$_{\odot}$yr$^{-1}$. For the assumed progenitor wind velocity of $v_w = 50$ km s$^{-1}$, this corresponds to enhanced mass-loss (i.e., ``super-wind'' phase) during the last $\sim$3-6 years before explosion., Comment: 19 pages, 8 figures. Accepted for publication in ApJL
Published: 2023

3. Exploration of Antimicrobial Peptides in the Treatment of Gentamicin-Resistant Klebsiella pneumoniae Infection

Author: Chen X, Zhang B, He J, Rui X, He T, Zhang L, Bao J, Jing Y, and Cao F
Subjects: klebsiella pneumoniae, k. pneumoniae, antibiotics, antimicrobial peptide, gentamicin-resistant, rt, microenvironment, Infectious and parasitic diseases, RC109-216
Abstract: Xiaochun Chen,1,&ast; Benhong Zhang,2,&ast; Jin He,3,&ast; Xiaohong Rui,4 Tian He,4 Lizhu Zhang,5 Junfeng Bao,6 Yanfei Jing,7 Futao Cao8 1Department of Laboratory Medicine, Taizhou Second People’s Hospital, Taizhou, People’s Republic of China; 2Department of Laboratory Medicine, Hangzhou Gongshu District Integrated Traditional Chinese and Western Medicine Hospital, Hangzhou, People’s Republic of China; 3Department of Laboratory Medicine, Hangzhou Yuhang Jiamu Nursing Home, Hangzhou, People’s Republic of China; 4Department of Laboratory Medicine, Affiliated Wuxi Fifth Hospital of Jiangnan University, Wuxi, People’s Republic of China; 5Department of Research, Nanxin Pharm, Nanjing, People’s Republic of China; 6Department of Laboratory Medicine, Wuxi Maternal and Child Health Care Hospital, Women’s Hospital of Jiangnan University, Wuxi, People’s Republic of China; 7Department of Function, Affiliated Wuxi Fifth Hospital of Jiangnan University, Wuxi, People’s Republic of China; 8Department of Emergency, Jiangnan University Medical Center, Wuxi, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yanfei Jing, Department of Function, Affiliated Wuxi Fifth Hospital of Jiangnan University, Wuxi, Jiangsu, 214005, People’s Republic of China, Email tengfeiba0002@163.com Futao Cao, Department of Emergency, Jiangnan University Medical Center, Wuxi, Jiangsu, 214000, People’s Republic of China, Email caofutao999@163.comIntroduction: The emergence of multidrug-resistant Klebsiella pneumoniae (K. pneumoniae) and the decline of effective antibiotics lead to the urgent need for new antibacterial agents. The aim of this study is to investigate the therapeutic effect of antimicrobial peptides against gentamicin-resistant (RT) K. pneumoniae and to screen effective antimicrobial peptides.Methods: In this study, the RT strains were induced by gradient gentamicin, and the RT strains were selected by detecting the expression levels of efflux pump genes, porin genes, and biofilm formation genes of the strains combined with their effects on the cells. Then the effects of four antimicrobial peptides on the efflux pump activity, biofilm formation level and cell condition after infection were detected to explore the effects of antimicrobial peptides on RT strains. Finally, the RT strain was used to induce a mouse model of pneumonia, and the four antimicrobial peptides were used to treat pneumonia mice for in vivo experiments. The pathological changes in lung tissues in each group were detected to explore the antimicrobial peptide with the most significant effect on the RT strain in vivo.Results: The results showed that the minimal inhibitory concentrations of the RT strains (strain C and strain I) were significantly higher than those of the wild-type strain, and the expression of efflux pump, porin and biofilm formation genes was significantly increased. The antimicrobial peptides could effectively inhibit the biofilm formation and efflux pump protein function of the RT strains. In addition, the antimicrobial peptides showed promising antibacterial effects both in vitro and in vivo.Discussion: Our study provided a theoretical basis for the treatment of gentamicin resistant K. pneumoniae infection with antimicrobial peptides, and found that KLA was significantly superior to LL37, Magainin I, KLA and Dermaseptin (10 μg/mL in cells, 50 μg in mice).Keywords: Klebsiella pneumoniae, K. pneumoniae, antibiotics, antimicrobial peptide, gentamicin-resistant, RT, microenvironment
Published: 2024

4. Mendelian Randomization Analysis of Circulating Cytokines and Risk of Autoimmune Neuroinflammatory Diseases

Author: Tao SS, Cao F, Zhang RD, Xu SZ, Li XX, Tang J, Yang XK, and Pan HF
Subjects: cytokines, autoimmune neuroinflammatory diseases, ands, causal relationship, mendelian randomization, Immunologic diseases. Allergy, RC581-607
Abstract: Sha-Sha Tao,1– 3,&ast; Fan Cao,4,&ast; Ruo-Di Zhang,1,2,&ast; Shu-Zhen Xu,1,2 Xiao-Xiao Li,1,2 Jian Tang,1,2 Xiao-Ke Yang,5 Hai-Feng Pan1,2 1Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People’s Republic of China; 2Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Hefei, Anhui, People’s Republic of China; 3Experimental Teaching Center for Preventive Medicine, School of Public Health, Anhui Medical University, Hefei, Anhui, People’s Republic of China; 4Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People’s Republic of China; 5Department of Rheumatology and Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Hai-Feng Pan, Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People’s Republic of China, Email panhaifeng1982@sina.com; panhaifeng@ahmu.edu.cnBackground: Cytokines act a vital role in autoimmune neuroinflammatory diseases (ANDs) with undetermined causal relationships. Mendelian randomization (MR) analysis was performed to estimate the causal effects of circulating levels of cytokines on the risk of ANDs.Methods: The causal relationship between 34 circulating cytokines and 4 kinds of ANDs, including multiple sclerosis (MS), neuromyelitis optica (NOM), chronic inflammatory demyelinating polyneuropathy (CIDP) and myasthenia gravis (MG) were explored using four methods of MR analysis. MR-PRESSO, MR-Egger regression methods and Cochran’s Q statistic were utilized to identify the instrumental variables (IVs) with potential pleiotropy and heterogeneity. The Bonferroni correction was used for multiple group comparisons. P-value less than 3.68E-04 (0.05/ (34&ast;4)) was considered statistically significant.Results: Negative causal effects of circulating levels of interleukin (IL)-8 (OR = 0.648, 95% CI: 0.494-0.851, P = 0.002) on risk of MS, chemokine (C–C Motif) ligand (CCL)-5 (OR = 0.295, 95% CI: 0.103-0.841, P = 0.022) and stem cell growth factor-beta (SCGF-β) (OR = 0.745, 95% CI: 0.565-0.984, P = 0.038) on risk of CIDP, as well as positive causal effects of circulating levels of IL-2 receptor α (IL-2Rα) (OR = 1.216, 95% CI: 1.120-1.320, P = 3.20E-06) and chemokine C-X-C motif ligand (CXCL)-10 (OR = 1.404, 95% CI: 1.094-1.803, P = 0.008) on MS were observed. Nevertheless, only IL-2Rα still had a causal effect on MS after Bonferroni correction.Conclusion: The results identify a genetically predicted causal effect of IL-2Rα, IL-8 and CXCL-10 on MS, CCL-5 and SCGF-β on CIDP.Keywords: cytokines, autoimmune neuroinflammatory diseases, ANDs, causal relationship, Mendelian randomization
Published: 2024

5. Deep underground laboratory measurement of $^{13}$C($\alpha$,$n$)$^{16}$O in the Gamow windows of the $s$- and $i$-processes

Author: Gao, B., Jiao, T. Y., Li, Y. T., Chen, H., Lin, W. P., An, Z., Ru, L. H., Zhang, Z. C., Tang, X. D., Wang, X. Y., Zhang, N. T., Fang, X., Xie, D. H., Fan, Y. H., Ma, L., Zhang, X., Bai, F., Wang, P., Fan, Y. X., Liu, G., Huang, H. X., Wu, Q., Zhu, Y. B., Chai, J. L., Li, J. Q., Sun, L. T., Wang, S., Cai, J. W., Li, Y. Z., Su, J., Zhang, H., Li, Z. H., Li, Y. J., Li, E. T., Chen, C., Shen, Y. P., Lian, G., Guo, B., Li, X. Y., Zhang, L. Y., He, J. J., Sheng, Y. D., Chen, Y. J., Wang, L. H., Zhang, L., Cao, F. Q., Nan, W., Nan, W. K., Li, G. X., Song, N., Cui, B. Q., Chen, L. H., Ma, R. G., Yan, S. Q., Liao, J. H., Wang, Y. B., Zeng, S., Nan, D., Fan, Q. W., Qi, N. C., Sun, W. L., Guo, X. Y., Zhang, P., Chen, Y. H., Zhou, Y., Zhou, J. F., He, J. R., Shang, C. S., Li, M. C., Kubono, S., Liu, W. P., deBoer, R. J., Wiescher, M., and Pignatari, M.
Subjects: Nuclear Experiment
Abstract: The $^{13}$C($\alpha$,$n$)$^{16}$O reaction is the main neutron source for the slow-neutron-capture (s-) process in Asymptotic Giant Branch stars and for the intermediate (i-) process. Direct measurements at astrophysical energies in above-ground laboratories are hindered by the extremely small cross sections and vast cosmic-ray induced background. We performed the first consistent direct measurement in the range of $E_{\rm c.m.}=$0.24 MeV to 1.9 MeV using the accelerators at the China Jinping Underground Laboratory (CJPL) and Sichuan University. Our measurement covers almost the entire i-process Gamow window in which the large uncertainty of the previous experiments has been reduced from 60\% down to 15\%, eliminates the large systematic uncertainty in the extrapolation arising from the inconsistency of existing data sets, and provides a more reliable reaction rate for the studies of the s- and i-processes along with the first direct determination of the alpha strength for the near-threshold state.
Published: 2022
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6. Analysis and Discussion on the Room Temperature Microstructure and Properties of High Content Mixed Rare-Earth As-Cast AZ61 Magnesium Alloy

Author: Cao, F. H., Zhang, Y., Chen, Y., Jiang, M. G., Zhou, J. L., and He, Y.
Published: 2023
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7. Efficacy and Safety of Maintenance Therapy Using Cetuximab in Patients with Metastatic Colorectal Cancer: Retrospective Study

Author: Xuan T, Wang Z, Meng S, Li J, Cao F, and Qu L
Subjects: colorectal cancer, maintenance therapy, cetuximab, ras and raf wild-type, targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Tiantian Xuan,1 Zhanmei Wang,1 Sibo Meng,1 Jiaxin Li,1 Jisheng Li,2 Fangli Cao,1,&ast; Linli Qu1,&ast; 1Department of Medical Oncology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, People’s Republic of China; 2Department of Medical Oncology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Fangli Cao; Linli Qu, Department of Medical Oncology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, Shandong, 266035, People’s Republic of China, Tel +86-18561811936 ; +86-18561811457, Email caofangliqilu@163.com; qulinli2021@163.comPurpose: Cetuximab (CET) combined with chemotherapy significantly improved the survival in RAS and RAF wild-type metastatic colorectal cancer (mCRC) patients, while clinical evidence was lacking on the use of maintenance therapy (MT). The study aimed to explore the role of maintenance therapy following Cetuximab + chemotherapy and the optimal Cetuximab-based maintenance therapy regimen.Patients and Methods: We retrospectively reviewed data on the efficacy and safety of CET-based MT in patients with mCRC who achieved disease control after induction therapy.Results: Eighty-one patients with mCRC who achieved disease control after CET + chemotherapy induction were enrolled. Overall median progression-free survival (PFS) was 10.5 (95% CI = 8.8– 12.2) months and median maintenance/observation PFS (mnPFS) was 6.0 (95% CI = 5.0– 7.0) months. Among these 81 patients, 61 patients were prescribed MT (CET alone for 21 patients and CET + chemotherapy for 40 patients). Median PFS and mnPFS in the MT group were significantly longer than those for the non-MT group. Different MT regimens did not affect PFS and mnPFS significantly. Univariate and multivariate analysis demonstrated MT, complete response/partial response during induction therapy, and absence of peritoneal metastasis to be positively associated with longer PFS and mnPFS. Treatment-related adverse events (AEs) were tolerable during MT, and AE-related deaths were not observed.Conclusion: MT with CET or CET + chemotherapy was an appropriate option following initial induction chemotherapy for patients with RAS and RAF wild-type mCRC. This strategy endowed survival benefits and a tolerable safety profile.Keywords: colorectal cancer, maintenance therapy, cetuximab, RAS and RAF wild-type, targeted therapy
Published: 2024

8. Factors Influencing the Choice of Automated Peritoneal Dialysis Treatment by Patients Receiving Home Peritoneal Dialysis

Author: Cao F, Hong F, Ruan Y, and Lin M
Subjects: peritoneal dialysis，apd, dialysis mode，influencing factors，follow up，end-stage kidney disease, Medicine (General), R5-920
Abstract: Fang Cao,1,2 Fuyuan Hong,1 Yiping Ruan,1 Miao Lin1 1Department of Nephrology, Provincial Clinical College, Fujian Medical University, Fujian Provincial Hospital, Fuzhou, 350001, People’s Republic of China; 2Department of Nursing, Provincial Clinical College, Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, 350001, People’s Republic of ChinaCorrespondence: Fang Cao; Miao Lin, Department of Nephrology, Provincial Clinical College, Fujian Medical University, Fujian Provincial Hospital, 134 East Street, Fuzhou, 350001, People’s Republic of China, Tel +86-591-87557768, Email 422512642@qq.com; 10151246@qq.comObjective: This study was conducted to understand the influencing factors for home peritoneal dialysis patients choosing APD and to provide a scientific basis for improving the completion rate of APD treatment and the follow-up of peritoneal dialysis patients.Methods: The study was a cross-sectional questionnaire-based study. A total of 588 patients on peritoneal dialysis were randomly selected from 6 regions in Fujian Province in southern China using a stratified cluster sampling method.Results: The mean age of the patients were 56.5 ± 14.73 years. In the univariate analysis, knowledge, user experience and family support were the factors that affected patients’ choice of APD (all P < 0.05) and were positively correlated with the treatment utilization rate. In the multivariate analysis, 3 factors (treatment with APD, knowledge of APD, and family support) remained significantly associated not choosing APD. The selection rate for APD was 2.594 times higher among patients who had received APD than among patients who had never received APD. The selection rate for patients with “a lot of knowledge” about APD was 10.75 times that of patients with “no knowledge”.Conclusion: Patients’ knowledge of APD, experience in application and family support were the main factors affecting the choice of APD as a treatment mode (P < 0.05) and were positively correlated with the treatment utilization rate. Further studies are needed to improve the APD treatment completion rates by modulation the above-mentioned factors.Relevance to Clinical Practice: This study provides scientific evidence for improving APD treatment completion rates and improving patient quality of life.Keywords: peritoneal dialysis, APD, dialysis mode, influencing factors, follow up, end-stage kidney disease
Published: 2023

9. Peripheral Blood Th1/Th17 Immune Cell Shift is Associated with Disease Activity and Severity of AQP4 Antibody Sero-Positive Neuromyelitis Optica Spectrum Disorder

Author: Cao F, Wang Y, Wei R, Li C, Cheng Y, Zhou Y, Jin T, Zhang H, Lin L, and Xu B
Subjects: neuromyelitis optica spectrum disorder, helper t cell, flow cytometry, lymphocyte subsets, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
Abstract: Fangzheng Cao,1,&ast; Yiqi Wang,2,&ast; Ruili Wei,3 Chunrong Li,2 Yifan Cheng,2 Yu Zhou,1 Tianyu Jin,1 Houwen Zhang,1 Luting Lin,4 Bin Xu5 1The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2Department of Neurology, Center for Rehabilitation Medicine, People’s Hospital of Hangzhou Medical College, Zhejiang Provincial People’s Hospital, Hangzhou, People’s Republic of China; 3Department of Neurology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 4School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 5Department of Neurology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Bin Xu, Department of Neurology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China, Email xubin2008.love@163.comPurpose: Neuromyelitis optica spectrum disorder (NMOSD) is a rare recurrent autoimmune disease of the central nervous system. However, to date, the peripheral blood profile of the T helper cell subsets in NMOSD remains controversial and poorly understood. This study aimed to compare the levels of helper T cell subsets in the peripheral blood from patients with NMOSD in different phases of the disease and studied their correlation with the clinical severity of the disease.Patients and methods: We used flow cytometry with cellular membrane surface staining to measure the levels of helper T cell subsets in 50 patients with NMOSD during the attack (n = 25) and remission (n = 25) phases and in 21 healthy controls.Results: Patients with NMOSD had higher levels of Th1 and Th17 cells in the attack phase compared to parallel populations in the remission phase and healthy controls. Th1/Th2 and Th17/Treg ratios were positively correlated with the severity of the disease in the attack phase of NMOSD. In contrast, Treg cell levels were negatively correlated with the severity of the disease in the attack phase in patients with NMOSD.Conclusion: The peripheral blood immune profile in NMOSD towards a Th1/Th17 cell-mediated pro-inflammatory immune response, which is associated with disease activity and severity of neuromyelitis optica spectrum disorder.Keywords: neuromyelitis optica spectrum disorder, helper T cell, flow cytometry, lymphocyte subsets
Published: 2023

10. Transverse Momentum and Transverse Momentum Distributions in the MIT Bag Model

Author: Signal, A. I. and Cao, F. G.
Subjects: High Energy Physics - Phenomenology, Nuclear Theory
Abstract: The typical transverse momentum of a quark in the proton is a basic property of any QCD based model of nucleon structure. However, calculations in phenomenological models typically give rather small values of transverse momenta, which are difficult to reconcile with the larger values observed in high energy experiments such as Drell-Yan reactions and Semi-inclusive deep inelastic scattering. In this letter we calculate the leading twist transverse momentum dependent distribution functions (TMDs) using a generalization of the Adelaide group's relativistic formalism that has previously given good fits to the parton distributions. This enables us to examine the $k_{T}$ dependence of the TMDs in detail, and determine typical widths of these distributions. These are found to be significantly larger than those of previous calculations. We then use TMD factorization in order to evolve these distributions up to experimental scales where we can compare with data on $\langle k_{T} \rangle$ and $\langle k^{2}_{T} \rangle$. Our distributions agree well with this data., Comment: 17 pages, 4 figures. Final version, accepted for publication in Physics Letters B
Published: 2021
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11. An in-Depth Exploration of the Genetic Interaction Network Between Ferroptosis and Acute Pancreatitis

Author: Li J, Jia Y, Cao F, Wang G, and Li F
Subjects: acute pancreatitis, ferroptosis, mitophagy, autophagy, inflammation, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
Abstract: Jie Li,1,2 Yuchen Jia,1,2 Feng Cao,1,2 Gang Wang,3 Fei Li1,2 1Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Clinical Center for Acute Pancreatitis, Capital Medical University, Beijing, People’s Republic of China; 3Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of ChinaCorrespondence: Fei Li; Gang Wang, Email feili36@ccmu.edu.cn; wgilu79@163.comBackground: Ferroptosis plays an important role in a variety of disease processes and is equally important in pancreatic diseases. However, the role of ferroptosis-related genes (FRGs) in acute pancreatitis (AP) remains unknown, and their specific potential mechanisms still need to be explored extensively.Methods: AP-related gene microarray data were obtained from the GEO database, while FRGs were obtained from the ferroptosis database (FerrDb). Differentially expressed genes (DEGs) were screened by the “limma” package, and GSEA was performed. The corresponding ferroptosis-related differentially expressed genes (FRDEGs) were screened, and GO and KEGG pathway analyses were performed. A PPI network was constructed to identify hub FRDEGs by CytoHubba, MCODE and CTD scores. Transcription factors and miRNAs predicted using the NetworkAnalyst database were used to establish the regulatory network. Immune cell infiltration analysis was performed by the R package “ssGSEA” algorithm. The hub genes were validated by transcriptome sequencing of AP model mice and immunohistochemistry in rats and mice.Results: A total of 82 FRDEGs were screened, and these genes were mainly associated with ferroptosis, hypoxic response, autophagy, mitophagy and immune inflammation. However, we also found that these genes are also jointly involved in other cell death modalities, such as apoptosis and necroptosis. Further analysis obtained 7 hub genes from 82 genes, and single-sample gene set enrichment analysis (ssGSEA) showed that the hub genes are closely associated with the infiltration of specific immune cells and the activation of immune pathways.Conclusion: This study reveals the complex functions and important roles of ferroptosis-related genes in AP and provides gene targets for further studies of AP.Keywords: acute pancreatitis, ferroptosis, mitophagy, autophagy, inflammation
Published: 2023

12. Standardizing Skullremodeling Surgery and Electrode Array Layout to Improve Tumor Treating Fields Using Computational Head Modeling and Finite Element Methods

Author: Mikic, N., Cao, F., Hansen, F. L., Jakobsen, A. M., Thielscher, A., Korshøj, A. R., Makarov, Sergey, editor, Noetscher, Gregory, editor, and Nummenmaa, Aapo, editor
Published: 2023
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13. Probing the core of the strong nuclear interaction

Author: Schmidt, A., Pybus, J. R., Weiss, R., Segarra, E. P., Hrnjic, A., Denniston, A., Hen, O., Piasetzky, E., Weinstein, L. B., Barnea, N., Strikman, M., Larionov, A., Higinbotham, D., Adhikari, S., Amaryan, M., Angelini, G., Asryan, G., Atac, H., Avakian, H., Gayoso, C. Ayerbe, Baashen, L., Barion, L., Bashkanov, M., Battaglieri, M., Beck, A., Bedlinskiy, I., Benmokhtar, F., Bianconi, A., Biselli, A. S., Bossu, F., Biarinov, S., Briscoe, W. J., Brooks, W., Burkert, V. D., Cao, F., Carman, D. S., Carvajal, J. C., Celentano, A., Chatagnon, P., Chetry, T., Ciullo, G., Clark, L., Cohen, E., Cole, P. L., Contalbrigo, M., Crede, V., Cruz-Torres, R., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Defurne, M., Deur, A., Diehl, S., Djalali, C., Duer, M., Dugger, M., Dupre, R., Egiyan, H., Ehrhart, M., Alaoui, A. El, Fassi, L. El, Eugenio, P., Filippi, A., Forest, T. A., Gavalian, G., Gilad, S., Gilfoyle, G. P., Giovanetti, K. L., Girod, F. X., Giuseppe, C., Glazier, D. I., Golovatch, E., Gothe, R. W., Griffioen, K. A., Guo, L., Hafidi, K., Hakobyan, H., Hanretty, C., Harrison, N., Hattawy, M., Hauenstein, F., Hayward, T. B., Hicks, K., Holtrop, M., Ilieva, Y., Illari, I., Ireland, D., Ishkanov, B. S., Isupov, E. L., Jenkins, D., Jo, H. S., Joo, K., Keller, D., Khachatryan, M., Khanal, A., Khandaker, M., Kim, C. W., Kim, W., Klein, F. J., Korover, I., Kubarovsky, V., Lanza, L., Leali, M., Lenisa, P., MacGregor, I. J. D., Marchand, D., Markov, N., Marsicano, L., Mascagna, V., Beck, S. May-Tal, McKinnon, B., Mirazita, M., Mokeev, V., Camacho, C. Munoz, Mustapha, B., Nadel-Turonski, P., Nanda, S., Niccolai, S., Niculescu, G., Osipenko, M., Ostrovidov, A. I., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Park, K., Pasyuk, E., Patsyuk, M., Phelps, W., Pogorelko, O., Price, J. W., Prok, Y., Protopopescu, D., Ripani, M., Riser, D., Rizzo, A., Rosner, G., Rossi, P., Sabatie, F., Salgado, C., Schmookler, B., Schumacher, R. A., Sharabian, Y. G., Shrestha, U., Skorodumina, Iu., Sokhan, D., Soto, O., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Tan, J. A., Tyler, N., Ungaro, M., Venturelli, L., Voskanyan, H., Voutier, E., Wang, R., Watts, D. P., Wei, X., Wood, M. H., Zachariou, N., Zhang, J., Zhao, Z. W., and Zheng, X.
Subjects: Nuclear Experiment, Nuclear Theory
Abstract: The strong nuclear interaction between nucleons (protons and neutrons) is the effective force that holds the atomic nucleus together. This force stems from fundamental interactions between quarks and gluons (the constituents of nucleons) that are described by the equations of Quantum Chromodynamics (QCD). However, as these equations cannot be solved directly, physicists resort to describing nuclear interactions using effective models that are well constrained at typical inter-nucleon distances in nuclei but not at shorter distances. This limits our ability to describe high-density nuclear matter such as in the cores of neutron stars. Here we use high-energy electron scattering measurements that isolate nucleon pairs in short-distance, high-momentum configurations thereby accessing a kinematical regime that has not been previously explored by experiments, corresponding to relative momenta above 400 MeV/c. As the relative momentum between two nucleons increases and their separation thereby decreases, we observe a transition from a spin-dependent tensor-force to a predominantly spin-independent scalar-force. These results demonstrate the power of using such measurements to study the nuclear interaction at short-distances and also support the use of point-like nucleons with two- and three-body effective interactions to describe nuclear systems up to densities several times higher than the central density of atomic nuclei., Comment: Total 26 pages, 13 figures. Main text: 8 pages, 3 figures. Methods section: 6 pages. Extended Data: 8 figures, 1 table. Supplementary Materials: 8 pages, 2 figures
Published: 2020
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14. Effect of Patient-Empowerment Interaction Model on Self-Management Ability of Peritoneal Dialysis Patients: A Randomized Controlled Trial

Author: Cao F, Hong F, Ruan Y, and Lin M
Subjects: patient empowerment；pbl；peritoneal dialysis；patient education；quality of life；chronic kidney disease, Medicine (General), R5-920
Abstract: Fang Cao, Fuyuan Hong, Yiping Ruan, Miao Lin Department of Nephrology, Provincial Clinical College, Fujian Medical University, Fujian Provincial Hospital, Fuzhou, 350001, People’s Republic of ChinaCorrespondence: Fang Cao; Miao Lin, Department of Nephrology, Provincial clinical college, Fujian Medical University, Fujian Provincial Hospital, 134 East Street, Fuzhou, People’s Republic of China, 350001, Tel/Fax +86-591-87557768, Email 422512642@qq.com; 10151246@qq.comObjective: Patient empowerment can be achieved through the PBL model. The purpose of the present study was to evaluate the effectiveness and feasibility of patient empowerment through the PBL model in health continuing education of peritoneal dialysis (PD) patients.Methods: From March 2017 to April 2017, a total of 94 participants were randomly assigned to the PBL group and the traditional group, with 47 patients in each group. Patients of the PBL group were divided into 5 study groups; and six PBL health education activities were held. The basic knowledge, self-management behavior, quality of life, anxiety, and depression were assessed among the traditional group and the PBL group. The average follow-up duration was 10.6± 1.5 months.Results: Compared with patients in the traditional group, patients in the PBL group had higher scores of basic knowledges for PD (84.33± 3.55 vs 91.19± 3.07; P< 0.001), higher scores of self-management (61.19± 3.71 vs 71.47± 2.89; P< 0.001), better scores of quality of life (85.99± 14.33 vs 102.64± 9.43; P < 0.001), and better scores of satisfaction (90.78± 1.32 vs 98.21± 1.25; P < 0.001). Furthermore, the scores of anxieties (52.39± 4.55 vs 46.46± 4.63; P < 0.001) and the scores of depressions were lower (49.95± 6.76 vs 45.80± 8.77; P =0.01) in patients who participated in the PBL mode of education than in the traditional educational group.Conclusion: The empowerment model of PBL health education can effectively improve the knowledge, skills and quality of life of PD patients.Relevance to Clinical Practice: The findings identified in this study will help to improve the quality of nursing care and health education for PD patients.Patient or Public Contribution: The study design involved patients on PD training. The knowledge and skills of PD and quality of life will improve after they participate the PBL health education activities.Keywords: patient empowerment, PBL, peritoneal dialysis, patient education, quality of life, chronic kidney disease
Published: 2023

15. Predictive Risk Factors of Pancreatic Exocrine Insufficiency Developed After Acute Pancreatitis: A Retrospective Cohort Study

Author: Guo Y, Wang X, Wang S, Li A, Cao F, and Li F
Subjects: acute pancreatitis, pancreatic exocrine insufficiency, modified computed tomography severity index, fecal elastase-1., Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
Abstract: Yulin Guo,1,2,&ast; Xiaohui Wang,1,2,&ast; Shuo Wang,1,2,&ast; Ang Li,1,2 Feng Cao,1,2 Fei Li1,2 1Department of General Surgery, Xuanwu Hospital of Capital Medical University, Beijing, People’s Republic of China; 2Acute Pancreatitis Clinical Center of Capital Medical University, Beijing, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Fei Li; Feng Cao, Department of General Surgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Beijing, 100053, People’s Republic of China, Tel/Fax +86-10-83198835, Email feili36@ccmu.edu.cn; caofeng1221@163.comPurpose: The aim of this study was to compare the clinical characteristics of acute pancreatitis (AP) patients between those who developed pancreatic exocrine insufficiency (PEI) and those who did not, and to investigate the predictive factors of PEI.Patients and Methods: From October 1st 2019 to July 30th 2021, AP patients admitted at our center were included. The fecal elastase-1 assay was adopted for PEI diagnosis. The clinical characteristics, treatments, and outcomes between the patients with and without PEI were analyzed.Results: In total, 63 males and 42 females were included. There were 27 patients with mild AP, 54 with moderately severe AP, and 24 with severe AP. The median modified computed tomography severity index (MCTSI) was 6.000(4.000, 8.000). During the follow-up, 38 patients developed PEI after AP. The univariate analysis showed that higher ASA grade (P = 0.006), more severe AP (P = 0.000), the presence of multiple organ dysfunction syndrome (P = 0.030), higher MCTSI (P = 0.000), the development of infected pancreatic necrosis (P = 0.002) and local complications (P = 0.000), higher levels of triacylglycerol (P = 0.022), video-assisted retroperitoneal debridement intervention (P = 0.015), and longer intensive care unit stay (P = 0.044) were correlated with PEI development. Furthermore, the logistic regression analyses showed that MCTSI during hospitalization is an independent risk factor for PEI development during the AP recovery period.Conclusion: ASA grade, severity of AP, multiple organ dysfunction syndrome, MCTSI, infected pancreatic necrosis, local complications, higher levels of triacylglycerol, video-assisted retroperitoneal debridement intervention, and longer intensive care unit stay were potentially associated with PEI development during the AP recovery period. High MCTSI was independently associated with the development of PEI during the AP recovery period, which may help alert to the possibility of PEI to help with its early detection and treatment.Keywords: acute pancreatitis, pancreatic exocrine insufficiency, modified computed tomography severity index, fecal elastase-1
Published: 2023

16. Effect of Extrusion Preforming Process on Microstructure and Mechanical Properties of AZ81 Magnesium Alloy Die-Forged Net Forming Specimen

Author: Cao, F. H., Chen, Y., Zhang, Y., Long, F., Qin, Z. H., Jiang, M. G., Xu, Y. H., Deng, C., Cao, H., Zhou, J. L., and He, Y.
Published: 2023
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17. Exploring the Structure of the Bound Proton with Deeply Virtual Compton Scattering

Author: Hattawy, M., Baltzell, N. A., Dupré, R., Bültmann, S., De Vita, R., Alaoui, A. El, Fassi, L. El, Egiyan, H., Girod, F. X., Guidal, M., Hafidi, K., Jenkins, D., Liuti, S., Perrin, Y., Stepanyan, S., Torayev, B., Voutier, E., Adhikari, S., Angelini, Giovanni, Gayoso, C. Ayerbe, Barion, L., Battaglieri, M., Bedlinskiy, I., Biselli, A. S., Bossù, F., Brooks, W., Cao, F., Carman, D. S., Celentano, A., Chatagnon, P., Chetry, T., Ciullo, G., Clark, L., Cole, P. L., Contalbrigo, M., Crede, V., D'Angelo, A., Dashyan, N., De Sanctis, E., Defurne, M., Deur, A., Diehl, S., Djalali, C., Ehrhart, M., Eugenio, P., Fegan, S., Filippi, A., Forest, T. A., Fradi, A., Garçon, M., Gavalian, G., Gevorgyan, N., Gilfoyle, G. P., Giovanetti, K. L., Golovatch, E., Gothe, R. W., Griffioen, K. A., Harrison, N., Hauenstein, F., Hayward, T. B., Heddle, D., Hicks, K., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Johnston, S., Keller, D., Khachatryan, G., Khachatryan, M., Khanal, A., Khandaker, M., Kim, C. W., Kim, W., Klein, F. J., Kubarovsky, V., Kuhn, S. E., Lanza, L., Kabir, M. L., Lenisa, P., Livingston, K., MacGregor, I. J. D., Marchand, D., Markov, N., Mayer, M., McKinnon, B., Meziani, Z. E., Mineeva, T., Mirazita, M., Montgomery, R. A., Camacho, C. Munoz, Nadel-Turonski, P., Niccolai, S., Ostrovidov, A. I., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Pogorelko, O., Poudel, J., Prok, Y., Protopopescu, D., Ripani, M., Riser, D., Rizzo, A., Rosner, G., Rossi, P., Sabatié, F., Salgado, C., Schumacher, R. A., Sharabian, Y. G., Skorodumina, Iu., Sokhan, D., Soto, O., Sparveris, N., Strauch, S., Taiuti, M., Tan, J. A., Tyler, N., Ungaro, M., Voskanyan, H., Wang, R., Watts, D. P., Wei, X., Weinstein, L. B., Wood, M. H., Zachariou, N., Zhang, J., and Zhao, Z. W.
Subjects: Nuclear Experiment, High Energy Physics - Experiment
Abstract: In the past two decades, deeply virtual Compton scattering of electrons has been successfully used to advance our knowledge of the partonic structure of the free proton and investigate correlations between the transverse position and the longitudinal momentum of quarks inside the nucleon. Meanwhile, the structure of bound nucleons in nuclei has been studied in inclusive deep-inelastic lepton scattering experiments off nuclear targets, showing a significant difference in longitudinal momentum distribution of quarks inside the bound nucleon, known as the EMC effect. In this work, we report the first beam spin asymmetry (BSA) measurement of exclusive deeply virtual Compton scattering (DVCS) off a proton bound in $^4$He. The data used here were accumulated using a $6$ GeV longitudinally polarized electron beam incident on a pressurized $^4$He gaseous target placed within the CLAS spectrometer in Hall-B at the Thomas Jefferson National Accelerator Facility. The azimuthal angle ($\phi$) dependence of the BSA was studied in a wide range of virtual photon and scattered proton kinematics. The $Q^2$, $x_B$, and t dependencies of the BSA on the bound proton are compared with those on the free proton. In the whole kinematical region of our measurements, the BSA on the bound proton is smaller by 20\% to 40\%, indicating possible medium modification of its partonic structure.
Published: 2018
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18. First Measurements of the Double-Polarization Observables $F$, $P$, and $H$ in $\omega$ Photoproduction off Transversely Polarized Protons in the $N^\ast$ Resonance Region

Author: Roy, P., Park, S., Crede, V., Anisovich, A. V., Klempt, E., Nikonov, V. A., Sarantsev, A. V., Wei, N. C., Huang, F., Nakayama, K., Adhikari, K. P., Adhikari, S., Angelini, G., Avakian, H., Barion, L., Battaglieri, M., Bedlinskiy, I., Biselli, A. S., Boiarinov, S., Briscoe, W. J., Brock, J., Brooks, W. K., Burkert, V. D., Cao, F., Carlin, C., Carman, D. S., Celentano, A., Chatagnon, P., Chetry, T., Ciullo, G., Cole, P. L., Contalbrigo, M., Cortes, O., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Deur, A., Diehl, S., Djalali, C., Dugger, M., Dupre, R., Duran, B., Egiyan, H., Ehrhart, M., Alaoui, A. El, Fassi, L. El, Eugenio, P., Fegan, S., Filippi, A., Fradi, A., Gilfoyle, G. P., Girod, F. X., Golovatch, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Guo, L., Hafidi, K., Hanretty, C., Harrison, N., Hattawy, M., Hayward, T. B., Heddle, D., Hicks, K., Holtrop, M., Ilieva, Y., Ireland, D. G., Ishkhanov, B. S., Isupov, E. L., Jenkins, D., Jo, H. S., Johnston, S., Joosten, S., Kabir, M. L., Keith, C. D., Keller, D., Khachatryan, G., Khachatryan, M., Khanal, A., Khandaker, M., Kim, A., Kim, W., Klein, F. J., Kubarovsky, V., Kuleshov, S. V., Kunkel, M. C., Lanza, L., Lenisa, P., Livingston, K., MacGregor, I. J. D., Marchand, D., McKinnon, B., Meekins, D. G., Meyer, C. A., Mineeva, T., Mokeev, V., Montgomery, R. A., Movsisyan, A, Camacho, C. Munoz, Nadel-Turonski, P., Niccolai, S., Niculescu, G., Osipenko, M., Ostrovidov, A. I., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Payette, D., Phelps, W., Pierce, J., Pogorelko, O., Prok, Y., Protopopescu, D., Raue, B. A., Ripani, M., Riser, D., Ritchie, B. G., Rizzo, A., Rosner, G., Sabatie, F., Salgado, C., Schumacher, R. A., Seely, M. L., Sharabian, Y. G., Shrestha, U., Skorodumina, Iu., Sokhan, D., Soto, O., Sparveris, N., Strakovsky, I. I., Strauch, S., Taiuti, M., Tan, J. A., Torayev, B., Tyler, N., Ungaro, M., Voskanyan, H., Voutier, E., Walford, N. K., Wang, R., Watts, D. P., Wei, X., Wood, M. H., Zachariou, N., Zhang, J., and Zhao, Z. W.
Subjects: Nuclear Experiment, High Energy Physics - Experiment
Abstract: First measurements of double-polarization observables in $\omega$ photoproduction off the proton are presented using transverse target polarization and data from the CEBAF Large Acceptance Spectrometer (CLAS) FROST experiment at Jefferson Lab. The beam-target asymmetry $F$ has been measured using circularly polarized, tagged photons in the energy range 1200 - 2700 MeV, and the beam-target asymmetries $H$ and $P$ have been measured using linearly polarized tagged photons in the energy range 1200 - 2000 MeV. These measurements significantly increase the database on polarization observables. The results are included in two partial-wave analyses and reveal significant contributions from several nucleon ($N^\ast$) resonances. In particular, contributions from new $N^\ast$ resonances listed in the Review of Particle Properties are observed, which aid in reaching the goal of mapping out the nucleon resonance spectrum., Comment: Two authors added, figures updated
Published: 2018
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19. Characteristics and Incidence of Colon Complication in Necrotizing pancreatitis: A Propensity Score-Matched Study

Author: Lu J, Zheng Z, Ding Y, Qu Y, Mei W, Fang Z, Qu C, Feng Y, Guo Y, Gao C, Cao F, and Li F
Subjects: necrotizing pancreatitis, colon involvement, propensity score match, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
Abstract: Jiongdi Lu,1,2,&ast; Zhi Zheng,3,&ast; Yixuan Ding,1,2 Yuanxu Qu,1,2 Wentong Mei,1,2 Zhen Fang,1,2 Chang Qu,1,2,&ast; Yulu Feng,4 Yulin Guo,1,2 Chongchong Gao,1,2 Feng Cao,1,2 Fei Li1,2 1Clinical Center of Acute Pancreatitis, Capital Medical University, Beijing, People’s Republic of China; 2Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China; 3Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China; 4Chui Yang Liu Hospital Affiliated Tsinghua University, Beijing, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Fei Li, Clinical Center of Acute Pancreatitis, Department of General Surgery, Department of Surgery, Xuanwu Hospital of Capital Medical University, No. 45, Changchun Street, Xicheng District, Beijing, 100053, People’s Republic of China, Tel +86-10-83198731, Fax +86-10-83198868, Email feili36@ccmu.edu.cn Feng Cao, Clinical Center of Acute Pancreatitis, Department of General Surgery, Xuanwu Hospital of Capital Medical University, No. 45, Changchun Street, Xicheng District, Beijing, 100053, People’s Republic of China, Email f.cao@xwhosp.orgObjective: To clarify the incidence of colonic complications in patients with NP and their impact on prognosis.Methods: The clinical data of NP patients admitted to the Department of General Surgery of Xuanwu Hospital, Capital Medical University from January 2014 to December 2020 were retrospectively analyzed. Patients were grouped according to the presence or absence of colonic complications, and the clinical prognosis of the two groups was analyzed after matching using a 1:1 propensity score, The primary study endpoint was patient mortality during hospitalization. Data are reported as median (range) or percentage of patients (%).Results: A total of 306 patients with NP were included in this study, and the incidence of colonic complications was 12.4%, including 15 cases of colonic obstruction, 17 cases of colonic fistula, and 9 cases of colonic hemorrhage. Before matching, patients in the colonic group had severe admissions and poor clinical outcomes (P< 0.05). After matching, the baseline data and clinical characteristics at admission were comparable between the two groups of patients. In terms of clinical outcomes, although the mortality was similar in the two groups (P> 0.05), but patients in the colonic group were more likely to have multiorgan failure, length of nutrition support, number of minimally invasive interventions, number of extra-pancreatic infections, length of ICU stay and total length of stay were significantly higher than those of patients in the group without colonic complications (P< 0.05). During long-term follow-up, patients in the colonic group were more likely to develop recurrent pancreatitis.Conclusion: About 12.4% of NP patients developed colonic complications, and after PSM it was found that colonic complications only led to a longer hospital stay and an increased number of clinical interventions in NP patients and did not increase the mortality.Keywords: necrotizing pancreatitis, colon involvement, propensity score match
Published: 2023

20. Risk Factors and Outcomes of Multidrug-Resistant Bacteria Infection in Infected Pancreatic Necrosis Patients

Author: Lu J, Ding Y, Qu Y, Mei W, Guo Y, Fang Z, Qu C, Gao C, Cao F, Li F, and Feng Y
Subjects: infected pancreatic necrosis, extra-pancreatic infection, multidrug-resistant bacteria, risk factor analysis, Infectious and parasitic diseases, RC109-216
Abstract: Jiongdi Lu,1,2 Yixuan Ding,1,2 Yuanxu Qu,1,2 Wentong Mei,1,2 Yulin Guo,1,2 Zhen Fang,1,2 Chang Qu,1,2 Chongchong Gao,1,2 Feng Cao,1,2,&ast; Fei Li,1,2,&ast; Yulu Feng3 1Clinical Center of Acute Pancreatitis, Capital Medical University, Beijing, People’s Republic of China; 2Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China; 3Department of Pediatric, Chui Yang Liu Hospital Affiliated Tsinghua University, Beijing, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Fei Li; Feng Cao, Clinical Center of Acute Pancreatitis, Capital Medical University, Department of General Surgery, Department of Surgery, Xuanwu Hospital, Capital Medical University, No. 45, Changchun Street, Xicheng District, Beijing, 100053, People’s Republic of China, Tel +86-10-83198731, Fax +86-10-83198868, Email feili36@ccmu.edu.cn; f.cao@xwhosp.orgObjective: The incidence of acute pancreatitis (AP) is increasing. Twenty percent of AP patients with developing necrotizing pancreatitis (NP), while ~40– 70% of NP patients develop potentially fatal infectious complications. When patients are suspected or confirmed infected pancreatic necrosis (IPN), antibiotics should be administered timeously to control the infection, but long-term use of antibiotics can lead to multidrug-resistant bacteria (MDRB) infection and eventually to increased mortality. Our study aimed to determine the incidence of MDRB infection and evaluate the risk factors for MDRB infection in IPN patients.Methods: Clinical data of IPN patients admitted to the general surgery department of Xuanwu Hospital of Capital Medical University between January 1, 2014, and December 31, 2021, were retrospectively analyzed.Results: IPN patients (n = 267) were assigned to MDRB infection (n = 124) and non-MDRB infection (n = 143) groups. On admission, patients in the MDRB group had a higher modified computer tomography severity index (CTSI) score (P < 0.05), pancreatic necrosis degree, and PCT level (P < 0.05) than those in the non-MDRB group, and the prognosis of patients in MDRB group was poor. The most common gram-negative bacteria were Acinetobacter baumannii (n = 117), the most common gram-positive bacteria were Enterococcus faecium (n = 98), and the most common fungal infection was Candida albicans (n = 47). Multivariable analysis showed that complications of EPI (OR: 4.116, 95% CI: 1.381– 12.271, P = 0.011), procalcitonin (PCT) level at admission (OR: 2.728, 95% CI: 1.502– 4.954, P = 0.001), and degree of pancreatic necrosis (OR: 2.741, 95% CI: 1.109– 6.775, P = 0.029) were independent risk factors for MDRB infection in IPN patients.Conclusion: We identified common infectious strains and risk factors for MDRB infection in IPN patients.Keywords: infected pancreatic necrosis, extra-pancreatic infection, multidrug-resistant bacteria, risk factor analysis
Published: 2022

21. Standardizing Skullremodeling Surgery and Electrode Array Layout to Improve Tumor Treating Fields Using Computational Head Modeling and Finite Element Methods

Author: Mikic, N., primary, Cao, F., additional, Hansen, F. L., additional, Jakobsen, A. M., additional, Thielscher, A., additional, and Korshøj, A. R., additional
Published: 2022
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22. LINC00839 Promotes the Progression of Gastric Cancer by Sponging miR-1236-3p

Author: An, J. X., Ma, Z. S., Yu, W. J., Xie, B. J., Zhu, F. S., Zhou, Y. X., and Cao, F. L.
Published: 2022
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23. First results on nucleon resonance photocouplings from the $\gamma p \to \pi^+\pi^-p$ reaction

Author: CLAS Collaboration, Golovatch, E., Burkert, V. D., Carman, D. S., Gothe, R. W., Hicks, K., Ishkhanov, B. S., Mokeev, V. I., Pasyuk, E., Adhikari, S., Akbar, Z., Amaryan, M. J., Avakian, H., Ball, J., Barion, L., Bashkanov, M., Battaglieri, M., Bedlinskiy, I., Biselli, A. S., Boiarinov, S., Briscoe, W. J., Cao, F., Celentano, A., Chatagnon, P., Chetry, T., Ciullo, G., Clark, L., Clary, B. A., Cole, P. L., Contalbrigo, M., Crede, V., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Defurne, M., Deur, A., Diehl, S., Djalali, C., Dugger, M., Dupre, R., Egiyan, H., Ehrhart, M., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Eugenio, P., Fedotov, G., Fersch, R., Filippi, A., Ghandilyan, Y., Gilfoyle, G. P., Giovanetti, K. L., Girod, F. X., Glazier, D. I., Griffioen, K. A., Guidal, M., Guo, L., Hafidi, K., Hakobyan, H., Harrison, N., Hattawy, M., Heddle, D., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jenkins, D., Jo, H. S., Johnston, S., Joo, K., Kabir, M. L., Keller, D., Khachatryan, G., Khachatryan, M., Khandaker, M., Kim, W., Klein, A., Klein, F. J., Kubarovsky, V., Lanza, L., Lenisa, P., Livingston, K., MacGregor, I. J. D., Marchand, D., Markov, N., McKinnon, B., Meyer, C. A., Montgomery, R. A., Movsisyan, A., Camacho, C. Munoz, Nadel-Turonski, P., Niccolai, S., Niculescu, G., Osipenko, M., Ostrovidov, A. I., Paolone, M., Paremuzyan, R., Park, K., Pogorelko, O., Price, J. W., Prok, Y., Protopopescu, D., Ripani, M., Riser, D., Rizzo, A., Rosner, G., Sabatié, F., Salgado, C., Schumacher, R. A., Sharabian, Y. G., Skorodumina, Iu., Smith, G. D., Sober, D. I., Sokhan, D., Sparveris, N., Strakovsky, I. I., Strauch, S., Taiuti, M., Tan, J. A., Tyler, N., Ungaro, M., Voskanyan, H., Voutier, E., Wang, R., Wei, X., Wood, M. H., Zachariou, N., Zhang, J., and Zhao, Z. W.
Subjects: Nuclear Experiment
Abstract: We report the first experimental measurements of the nine 1-fold differential cross sections for the $\gamma p \to \pi^+\pi^-p$ reaction, obtained with the CLAS detector at Jefferson Laboratory. The measurements cover the invariant mass range of the final state hadrons from 1.6~GeV~$
Published: 2018
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24. Beam-Target Helicity Asymmetry $E$ in $K^{0}\Lambda$ and $K^{0}\Sigma^0$ Photoproduction on the Neutron

Author: CLAS Collaboration, Ho, D. H., Schumacher, R. A., D'Angelo, A., Deur, A., Fleming, J., Hanretty, C., Kageya, T., Klein, F. J., Klempt, E., Lowry, M. M., Lu, H., Nikonov, V. A., Peng, P., Sandorfi, A. M., Sarantsev, A. V., Strakovsky, I. I., Walford, N. K., Wei, X., Workman, R. L., Adhikari, K. P., Adhikari, S., Adikaram, D., Akbar, Z., Ball, J., Barion, L., Bashkanov, M., Bass, C. D., Battaglieri, M., Bedlinskiy, I., Biselli, A. S., Briscoe, W. J., Boiarinov, S., Burkert, V. D., Cao, F., Carman, D. S., Celentano, A., Chandavar, S., Charles, G., Chatagnon, P., Chetry, T., Ciullo, G., Clary, B. A., Cole, P., Contalbrigo, M., Crede, V., De Vita, R., Defurne, M., Diehl, S., Djalali, C., Dupre, R., Egiyan, H., Ehrhart, M., Alaoui, A. El, Fassi, L. El, Eugenio, P., Fedotov, G., Fegan, S., Fersch, R., Filippi, A., Fradi, A., Ghandilyan, Y., Giovanetti, K. L., Girod, F. X., Gohn, W., Golovatch, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Hafidi, K., Hakobyan, H., Harrison, N., Hattawy, M., Heddle, D., Hicks, K., Holtrop, M., Ilieva, Y., Ireland, D. G., Ishkhanov, B. S., Isupov, E. L., Jenkins, D., Jo, H. S., Johnston, S., Kabir, M. L., Keller, D., Khachatryan, G., Khachatryan, M., Khandaker, M., Kim, A., Kim, W., Klein, A., Kubarovsky, V., Laine, V., Lanza, L., Lenisa, P., Livingston, K., MacGregor, I . J . D., Marchand, D., Markov, N., Mayer, M., McKinnon, B., Meyer, C. A., Mirazita, M., Mokeev, V., Montgomery, R. A., Movsisyan, A, Camacho, C. Munoz, Nadel-Turonski, P., Niccolai, S., Niculescu, G., O'Connell, T., Osipenko, M., Ostrovidov, A. I., Paolone, M., Paremuzyan, R., Park, K., Pasyuk, E., Pogorelko, O., Price, J. W., Prok, Y., Protopopescu, D., Rehfuss, M., Ripani, M., Riser, D., Rizzo, A., Rosner, G., Sabatié, F., Salgado, C., Sharabian, Y. G., Skorodumina, Iu., Smith, G. D., Sober, D. I., Sokhan, D., Sparveris, N., Strauch, S., Taiuti, M., Tan, J. A., Ungaro, M., Voskanyan, H., Voutier, E., Wang, R., Watts, D. P., Weinstein, L. B., Whisnant, C. S., Wood, M. H., Zachariou, N., Zhang, J., Zhao, Z. W., and Zonta, I.
Subjects: Nuclear Experiment
Abstract: We report the first measurements of the $E$ beam-target helicity asymmetry for the $\vec{\gamma} \vec{n} \to K^{0}\Lambda$, and $K^{0}\Sigma^{0}$ channels in the energy range 1.70$\leq W\leq$2.34 GeV. The CLAS system at Jefferson Lab uses a circularly polarized photon beam and a target consisting of longitudinally polarized solid molecular hydrogen deuteride with low background contamination for the measurements. The multivariate analysis method boosted decision trees was used to isolate the reactions of interest. Comparisons with predictions from the KaonMAID, SAID, and Bonn-Gatchina models are presented. These results will help separate the isospin $I=0$ and $I=1$ photo-coupling transition amplitudes in pseudoscalar meson photoproduction., Comment: 14 pages, 9 figures; Revised to match published version
Published: 2018
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25. Double $K_S^0$ Photoproduction off the Proton at CLAS

Author: Chandavar, S., Goetz, J. T., Hicks, K., Keller, D., Kunkel, M. C., Paolone, M., Weygand, D. P., Adhikari, K. P., Adhikari, S., Akbar, Z., Ball, J., Balossino, I., Barion, L., Bashkanov, M., Battaglieri, M., Bedlinskiy, I., Biselli, A. S., Briscoe, W. J., Brooks, W. K., Burkert, V. D., Cao, F., Carman, D. S., Celentano, A., Charles, G., Chetry, T., Ciullo, G., Clark, L., Cole, P. L., Contalbrigo, M., Crede, V., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Defurne, M., Deur, A., Djalali, C., Dupre, R., Egiyan, H., Alaoui, A. El, Fassi, L. El, Eugenio, P., Fedotov, G., Filippi, A., Fradi, A., Gavalian, G., Ghandilyan, Y., Gilfoyle, G. P., Girod, F. X., Glazier, D. I., Gohn, W., Golovatch, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Guo, L., Hafidi, K., Hakobyan, H., Hanretty, C., Harrison, N., Hattawy, M., Heddle, D., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jenkins, D., Johnston, S., Joo, K., Joosten, S., Kabir, M. L., Khachatryan, G., Khachatryan, M., Khandaker, M., Kim, W., Klein, A., Klein, F. J., Kubarovsky, V., Lanza, L., Lenisa, P., Livingston, K., MacGregor, I. J. D., Markov, N., McCracken, M. E., McKinnon, B., Meyer, C. A., Mineeva, T., Mokeev, V., Movsisyan, A, Camacho, C. Munoz, Nadel-Turonski, P., Niccolai, S., Niculescu, G., Osipenko, M., Ostrovidov, A. I., Paremuzyan, R., Park, K., Pasyuk, E., Phelps, W., Pogorelko, O., Price, J. W., Prok, Y., Protopopescu, D., Raue, B. A., Ripani, M., Riser, D., Ritchie, B. G., Rizzo, A., Rosner, G., Sabatie, F., Salgado, C., Schumacher, R. A., Sharabian, Y. G., Simonyan, A., Skorodumina, Iu., Sokhan, D., Smith, G. D., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Ungaro, M., Voutier, E., Wei, X., Zachariou, N., Zhang, J., and Zhao, Z. W.
Subjects: Nuclear Experiment
Abstract: The $f_0$(1500) meson resonance is one of several contenders to have significant mixing with the lightest glueball. This resonance is well established from several previous experiments. Here we present the first photoproduction data for the $f_0$(1500) via decay into the $K_S^0 K_S^0$ channel using the CLAS detector. The reaction $\gamma p$ -> $f_0 p$ -> $K_S^0 K_S^0 p$, where J = 0, 2, was measured with photon energies from 2.7 to 5.1 GeV. A clear peak is seen at 1500 MeV in the background subtracted invariant mass spectra of the two kaons. This is enhanced if the measured 4-momentum transfer to the proton target is restricted to be less than 1.0 GeV2. By comparing data with simulations, it can be concluded that the peak at 1500 MeV is produced primarily at low t, which is consistent with a t-channel production mechanism., Comment: 12 pages, 12 figures
Published: 2017
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26. Measurement of the Q^2 Dependence of the Deuteron Spin Structure Function g_1 and its Moments at Low Q^2 with CLAS

Author: Adhikari, K. P., Deur, A., Fassi, L. El, Kang, H., Kuhn, S. E., Ripani, M., Slifer, K., Zheng, X., Adhikari, S., Akbar, Z., Amaryan, M. J., Avakian, H., Ball, J., Balossino, I., Barion, L., Battaglieri, M., Bedlinskiy, I., Biselli, A. S., Bosted, P., Briscoe, W. J., Brock, J., Bueltmann, S., Burkert, V. D., Cao, F. Thanh, Carlin, C., Carman, D. S., Celentano, A., Charles, G., Chen, J. -P., Chetry, T., Choi, S., Ciullo, G., Clark, L., Cole, P. L., Contalbrigo, M., Crede, V., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Defurne, M., Djalali, C., Dodge, G. E., Drozdov, V., Dupre, R., Egiyan, H., Alaoui, A. El, Elouadrhiri, L., Eugenio, P., Fedotov, G., Filippi, A., Ghandilyan, Y., Gilfoyle, G. P., Golovatch, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Guler, N., Guo, L., Hafidi, K., Hakobyan, H., Hanretty, C., Harrison, N., Hattawy, M., Heddle, D., Hicks, K., Holtrop, M., Hyde, C. E., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jenkins, D., Jo, H. S., Johnston, S. C., Joo, K., Joosten, S., Kabir, M. L., Keith, C. D., Keller, D., Khachatryan, G., Khachatryan, M., Khandaker, M., Kim, W., Klein, A., Klein, F. J., Konczykowski, P., Kovacs, K., Kubarovsky, V., Lanza, L., Lenisa, P., Livingston, K., Long, E., MacGregor, I . J . D., Markov, N., Mayer, M., McKinnon, B., Meekins, D. G., Meyer, C. A., Mineeva, T., Mirazita, M., Mokeev, V., Movsisyan, A, Camacho, C. Munoz, Nadel-Turonski, P., Niculescu, G., Niccolai, S., Osipenko, M., Ostrovidov, A. I., Paolone, M., Pappalardo, L., Paremuzyan, R., Park, K., Pasyuk, E., Payette, D., Phelps, W., Phillips, S. K., Pierce, J., Pogorelko, O., Poudel, J., Price, J. W., Prok, Y., Protopopescu, D., Raue, B. A., Rizzo, A., Rosner, G., Rossi, P., Sabatie, F., Salgado, C., Schumacher, R. A., Sharabian, Y. G., Shigeyuki, T., Simonyan, A., Skorodumina, Iu., Smith, G. D., Sparveris, N., Sokhan, D., Stepanyan, S., Strakovsky, I. I., Strauch, S., Sulkosky, V., Taiuti, M., Tan, J. A., Ungaro, M., Voutier, E., Wei, X., Weinstein, L. B., Zhang, J., and Zhao., Z. W.
Subjects: Nuclear Experiment
Abstract: We measured the $g_1$ spin structure function of the deuteron at low $Q^{2}$, where QCD can be approximated with chiral perturbation theory ($\chi$PT). The data cover the resonance region, up to an invariant mass of $W\approx1.9$~GeV. The generalized Gerasimov-Drell-Hearn sum, the moment $\bar{\Gamma}_{1}^{d}$ and the integral $\bar{I}_\gamma^d$ related to the spin polarizability $\gamma_{0}^{d}$ are precisely determined down to a minimum $Q^2$ of 0.02~GeV$^2$ for the first time, about 2.5 times lower than that of previous data. We compare them to several $\chi$PT calculations and models. These results are the first in a program of benchmark measurements of polarization observables in the $\chi$PT domain., Comment: Version 1: version published in Phys. Rev. Lett. 6 pages, 3 figures. Supplementary material: data table for g1d and its moments (10 pages) V2: Figures labels changed and text slightly modified to clarify the exact nature of the measured moments V3: Corrected a typo page 5 for the theoretical value expected for deuteron GDH sum rule (agreement between measurement and expectation is improved)
Published: 2017
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27. How Efficient are Basic Public Health Services Between Urban and Rural in Shandong Province, China? A Data Envelopment Analysis and Panel Tobit Regression Approach

Author: Cao F, Xi Y, Zheng C, Bai T, and Sun Q
Subjects: basic public health services efficiency, urban, rural, data envelopment analysis, panel tobit regression, Public aspects of medicine, RA1-1270
Abstract: Fankun Cao,1,2 Yan Xi,3 Chao Zheng,1,2 Tongyu Bai,4 Qiang Sun1,2 1Center for Health Management and Policy Research of Public Health School, Shandong University, Jinan, Shandong Province, People’s Republic of China; 2NHC Key Lab of Health Economics and Policy Research (Shandong University), Shandong University, Jinan, Shandong Province, People’s Republic of China; 3Health Commission of Shandong Province, Jinan, Shandong Province, People’s Republic of China; 4Primary Health Department, Health Commission of Shandong Province, Jinan, Shandong Province, People’s Republic of ChinaCorrespondence: Qiang Sun, Email qiangs@sdu.edu.cnBackground: Improving basic public health services efficiency becomes priority to guarantee its sustainability for Chinese government. This study aimed to explore basic public health services efficiency and its influencing factors between urban and rural in Shandong Province, China, providing policy implications to improve efficiency.Methods: This research assessed basic public health services efficiency of 54 districts (representing urban) and 83 counties (representing rural) in Shandong, China, from 2014 to 2019. The data were obtained from Medical Management Service Center of Shandong Health Commission and Statistical Yearbooks. Input variables were subsidy funds, public health staffs and material expenditures. Output variables were assessment indicators covered all service contents from national standard. The data envelopment analysis and panel tobit regression were used to measure efficiency scores and efficiency influencing factors.Results: Basic public health services efficiency scores of urban were higher than those of rural during 2014 to 2019. Scale efficiency change and technological change promoted basic public health services total factor productivity change of urban and rural respectively. Panel tobit regression indicated that proportion of health expenditures in general public budget expenditures (P< 0.01), subsidy funds (P< 0.01), public health personnel expenditures (P< 0.01) and the frequency of professional health institutions’ guidance (P< 0.01) were positively associated with efficiency in both urban and rural. The number of primary medical and health institutions and public health personnel were positively associated with urban (P< 0.01), but those did not affect rural (P> 0.10).Conclusion: To improve basic public health services efficiency, urban should focus on health resource structure, especially increasing primary medical and health institutions and public health personnel. Rural should expand the input scale, paying more attention to subsidy funds and public health personnel expenditures. The government should also care strengthening the guidance to primary medical and health institutions from professional health institutions.Keywords: basic public health services efficiency, urban, rural, data envelopment analysis, panel tobit regression
Published: 2022

28. Measurement of the helicity asymmetry $E$ in $\omega\to\pi^+\pi^-\pi^0$ photoproduction

Author: Akbar, Z., Roy, P., Park, S., Crede, V., Anisovich, A. V., Denisenko, I., Klempt, E., Nikonov, V. A., Sarantsev, A. V., Adhikari, K. P., Adhikari, S., Amaryan, M. J., Pereira, S. Anefalos, Avakian, H., Ball, J., Battaglieri, M., Batourine, V., Bedlinskiy, I., Boiarinov, S., Briscoe, W. J., Brock, J., Brooks, W. K., Burkert, V. D., Cao, F. T., Carlin, C., Carman, D. S., Celentano, A., Charles, G., Chetry, T., Ciullo, G., Clark, L., Cole, P. L., Contalbrigo, M., Cortes, O., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Deur, A., Djalali, C., Dugger, M., Dupre, R., Egiyan, H., Fassi, L. El, Eugenio, P., Fedotov, G., Fersch, R., Filippi, A., Fradi, A., Garcon, M., Gevorgyan, N., Giovanetti, K. L., Girod, F. X., Gleason, C., Gohn, W., Golovach, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Guo, L., Hafidi, K., Hakobyan, H., Hanretty, C., Harrison, N., Hattawy, M., Heddle, D., Hicks, K., Hollis, G., Holtrop, M., Ireland, D. G., Ishkhanov, B. S., Isupov, E. L., Jenkins, D., Joosten, S., Keith, C. D., Keller, D., Khachatryan, G., Khachatryan, M., Khandaker, M., Kim, A., Kim, W., Klein, A., Klein, F. J., Kubarovsky, V., Lanza, L., Livingston, K., MacGregor, I. J. D., Markov, N., McKinnon, B., Meekins, D. G., Mineeva, T., Mokeev, V., Movsisyan, A., Camacho, C. Munoz, Nadel-Turonski, P., Niccolai, S., Osipenko, M., Ostrovidov, A. I., Paolone, M., Paremuzyan, R., Park, K., Pasyuk, E., Phelps, W., Pogorelko, O., Price, J. W., Prok, Y., Protopopescu, D., Raue, B. A., Ripani, M., Ritchie, B. G., Rizzo, A., Rosner, G., Sabatie, F., Salgado, C., Schumacher, R. A., Sharabian, Y. G., Skorodumina, Iu., Smith, G. D., Sober, D. I., Sokhan, D., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Taiuti, M., Ungaro, M., Voskanyan, H., Voutier, E., Wei, X., Wood, M. H., Zachariou, N., Zana, L., Zhang, J., and Zhao, Z. W.
Subjects: Nuclear Experiment, High Energy Physics - Experiment
Abstract: The double-polarization observable $E$ was studied for the reaction $\gamma p\to p\omega$ using the CEBAF Large Acceptance Spectrometer (CLAS) in Hall B at the Thomas Jefferson National Accelerator Facility and the longitudinally-polarized frozen-spin target (FROST). The observable was measured from the charged decay mode of the meson, $\omega\to\pi^+\pi^-\pi^0$, using a circularly-polarized tagged-photon beam with energies ranging from the $\omega$ threshold at 1.1 to 2.3 GeV. A partial-wave analysis within the Bonn-Gatchina framework found dominant contributions from the $3/2^+$ partial wave near threshold, which is identified with the sub-threshold $N(1720)\,3/2^+$ nucleon resonance. To describe the entire data set, which consisted of $\omega$ differential cross sections and a large variety of polarization observables, further contributions from other nucleon resonances were found to be necessary. With respect to non-resonant mechanisms, $\pi$ exchange in the $t$-channel was found to remain small across the analyzed energy range, while pomeron $t$-channel exchange gradually grew from the reaction threshold to dominate all other contributions above $W \approx 2$ GeV., Comment: 12 pages, 8 figures
Published: 2017
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29. Tagged EMC Measurements on Light Nuclei

Author: Armstrong, Whitney, Arrington, John, Cloet, Ian, Hafidi, Kawtar, Hattawy, Mohammad, Potteveld, David, Reimer, Paul, Riordan, Seamus, Yi, Z., Ball, Jacques, Defurne, Maxime, Garcon, Michel, Moutarde, Herve, Procureur, Sebastien, Sabatie, Franck, Cosyn, Wim, Mazouz, Malek, Accardi, Alberto, Bettane, Julien, Charles, Gabriel, Dupre, Raphael, Guidal, Michel, Marchand, Dominique, Munoz, Carlos, Niccolai, Silvia, Voutier, Eric, Adhikari, Krishna, Dunne, James, Dutta, Dipangkar, Fassi, Lamiaa El, Ye, Li, Amarian, Moskov, Dodge, Gail, Guzey, Vadim, Baltzell, Nathan, Girod, Francois-Xavier, Keppel, Cynthia, Stepanyan, Stepan, Duran, Burcu, Joosten, Sylvester, Meziani, Zein-Eddine, Paolone, Michael, Rehfuss, Melanie, Sparveris, Nikos, Cao, F., Joo, Kyungseon, Kim, Andrei, Markov, N., Atti, Claudio Ciofi degli, Scopetta, Sergio, Brooks, William, El-Alaoui, Ahmed, and Liuti, Simonetta
Subjects: Nuclear Experiment
Abstract: We propose to measure tagged deep inelastic scattering from light nuclei (deuterium and $^4$He) by detecting the low energy nuclear spectator recoil (p, $^3$H and $^3$He) in addition to the scattered electron. The proposed experiment will provide stringent tests leading to clear differentiation between the many models describing the EMC effect, by accessing the bound nucleon virtuality through its initial momentum at the point of interaction. Indeed, conventional nuclear physics explanations of the EMC effect mainly based on Fermi motion and binding effects yield very different predictions than more exotic scenarios, where bound nucleons basically loose their identity when embedded in the nuclear medium. By distinguishing events where the interacting nucleon was slow, as described by a mean field scenario, or fast, very likely belonging to a correlated pair, will clearly indicate which phenomenon is relevant to explain the EMC effect. An important challenge for such measurements using nuclear spectators is the control of the theoretical framework and, in particular, final state interactions. This experiment will directly provide the necessary data needed to test our understanding of spectator tagging and final state interactions in $^2$H and $^4$He and their impact on the semi-inclusive measurements of the EMC effect described above.
Published: 2017

30. Partonic Structure of Light Nuclei

Author: Armstrong, Whitney, Arrington, John, Cloet, Ian, Hafidi, Kawtar, Hattawy, Mohammad, Potteveld, David, Reimer, Paul, Riordan, Seamus, Yi, Z., Ball, Jacques, Defurne, Maxime, Garcon, Michel, Moutarde, Herve, Procureur, Sebastien, Sabatie, Franck, Cosyn, Wim, Mazouz, Malek, Bettane, Julien, Charles, Gabriel, Dupre, Raphael, Guidal, Michel, Marchand, Dominique, Munoz, Carlos, Niccolai, Silvia, Voutier, Eric, Adhikari, Krishna, Dunne, James, Dutta, Dipangkar, Fassi, Lamiaa El, Ye, Li, Guzey, Vadim, Baltzell, Nathan, Girod, Francois-Xavier, Stepanyan, Stepan, Duran, Burcu, Joosten, Sylvester, Meziani, Zein-Eddine, Paolone, Michael, Rehfuss, Melanie, Sparveris, Nikos, Cao, F., Joo, Kyungseon, Kim, Andrei, Markov, N., Scopetta, Sergio, Brooks, William, El-Alaoui, Ahmed, and Liuti, Simonetta
Subjects: Nuclear Experiment
Abstract: We propose to study the partonic structure of $^4$He by measuring the Beam Spin Asymmetry (BSA) in coherent Deeply Virtual Compton Scattering (DVCS) and the differential cross-section of the Deeply Virtual Meson Production (DVMP) of the $\phi$. Despite its simple structure, a light nucleus such as $^4$He has a density and a binding energy comparable to that of heavier nuclei. Therefore, by studying $^4$He nucleus, one can learn typical features of the partonic structure of atomic nuclei. The combination of CLAS12 and the ALERT detector provides a unique opportunity to study both the quark and gluon structure of a dense light nucleus. Coherent exclusive DVCS off $^4$He will probe the transverse spatial distribution of quarks in the nucleus as a function of the quarks' longitudinal momentum fraction, $x$. In parallel, the average spatial transverse gluon density of the $^4$He nucleus will be extracted within a GPD framework using the measured longitudinal cross-section for coherent $\phi$ production in a similar range of $x$. Additionally, threshold effects of $\phi$ production can be explored by exploiting the ALERT detector's large acceptance for low $|t|$ events.
Published: 2017

31. Digital Twin for Model Based Operational Support: Innovative Applications

Author: Ogugbue, C. E., additional, Greenawalt, Z., additional, Kondratenko, Y., additional, Dokun, T., additional, Stewart, C., additional, Cao, F., additional, Hosein, S., additional, and Burbank, W., additional
Published: 2024
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32. Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment

Author: Liu, Z., primary, Lin, Z., additional, Jiang, M., additional, Zhu, G., additional, Xiong, T., additional, Cao, F., additional, Cui, Y., additional, and Niu, Y., additional
Published: 2024
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33. Analysis and Discussion on the Room Temperature Microstructure and Properties of High Content Mixed Rare-Earth As-Cast AZ61 Magnesium Alloy

Author: Cao, F. H., primary, Zhang, Y., additional, Chen, Y., additional, Jiang, M. G., additional, Zhou, J. L., additional, and He, Y., additional
Published: 2024
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34. Dissecting Prognosis Modules and Biomarkers in Glioblastoma Based on Weighted Gene Co-Expression Network Analysis

Author: Cao F, Fan Y, Yu Y, Yang G, and Zhong H
Subjects: gbm, cgga, tcga, wgcna, biomarkers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Fang Cao,1,&ast; Yinchun Fan,1,&ast; Yunhu Yu,2 Guohua Yang,3 Hua Zhong4 1Department of Cerebrovascular Disease, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563000, People’s Republic of China; 2Clinical Research Center for Neurological Disease, the People’s Hospital of Hong Hua Gang District of ZunYi, Zunyi, 563000, People’s Republic of China; 3Demonstration Center for Experimental Basic Medicine Education of Wuhan University, Wuhan, Hubei, 430071, People’s Republic of China; 4College of Life Sciences, Wuhan University, Wuhan, Hubei, 430072, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Hua Zhong Email zhonghua0103@whu.edu.cnIntroduction: As one of the most prevalent and malignant brain cancers, glioblastoma multiforme (GBM) presents a poor prognosis and the molecular mechanisms remain poorly understood. Consequently, molecular research, including various biomarkers, is essential to exploit the occurrence and development of glioma.Methods: Weighted gene co-expression network analysis (WGCNA) was used to construct gene co-expression modules and networks based on the Chinese Glioma Genome Atlas (CGGA) glioblastoma specimens. Then, protein–protein interaction (PPI) and gene ontology (GO) analyses were performed to mine hub genes. RT-PCR and immunohistochemistry were employed to examine the expression level of GRPR, CXCL5, and CXCL11 in glioma patients.Results: We confirmed two gene modules by protein–protein interaction networks. Functional enrichment analysis was performed to identify the significance of gene modules. Prognostic biomarkers GRPR, CXCL5, and CXCL11 related to the survival time of GBM samples were mined in The Cancer Genome Atlas (TCGA) dataset. qRT-PCR revealed that GRPR, CXCL5, and CXCL11 led to a significant increase in GBM sample compared to control.Conclusion: In this study, we developed and confirmed three mRNA signatures (GRPR, CXCL5, and CXCL11) for evaluating overall survival in GBM patients. Our research assists in existing understanding of GBM diagnosis and prognosis.Keywords: GBM, CGGA, TCGA, WGCNA, biomarkers
Published: 2021

35. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author: Brauer, M, Roth, G, Aravkin, A, Zheng, P, Abate, K, Abate, Y, Abbafati, C, Abbasgholizadeh, R, Abbasi, M, Abbasian, M, Abbasifard, M, Abbasi-Kangevari, M, Abd ElHafeez, S, Abd-Elsalam, S, Abdi, P, Abdollahi, M, Abdoun, M, Abdulah, D, Abdullahi, A, Abebe, M, Abedi, A, Abegaz, T, Abeldaño Zuñiga, R, Abiodun, O, Abiso, T, Aboagye, R, Abolhassani, H, Abouzid, M, Aboye, G, Abreu, L, Abualruz, H, Abubakar, B, Abu-Gharbieh, E, Abukhadijah, H, Aburuz, S, Abu-Zaid, A, Adane, M, Addo, I, Addolorato, G, Adedoyin, R, Adekanmbi, V, Aden, B, Adetunji, J, Adeyeoluwa, T, Adha, R, Adibi, A, Adnani, Q, Adzigbli, L, Afolabi, A, Afolabi, R, Afshin, A, Afyouni, S, Afzal, M, Afzal, S, Agampodi, S, Agbozo, F, Aghamiri, S, Agodi, A, Agrawal, A, Agyemang-Duah, W, Ahinkorah, B, Ahmad, A, Ahmad, D, Ahmad, F, Ahmad, N, Ahmad, S, Ahmad, T, Ahmed, A, Ahmed, L, Ahmed, M, Ahmed, S, Ajami, M, Akalu, G, Akara, E, Akbarialiabad, H, Akhlaghi, S, Akinosoglou, K, Akinyemiju, T, Akkaif, M, Akkala, S, 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Subah Abderehim, Yezli, Saber, Yi, Siyan, Yiğit, Arzu, Yigzaw, Zeamanuel Anteneh, Yin, Dehui, Yip, Paul, Yismaw, Malede Berihun, Yon, Dong Keon, Yonemoto, Naohiro, You, Yuyi, Younis, Mustafa Z, Yousefi, Zabihollah, Yu, Chuanhua, Yu, Yong, Zadey, Siddhesh, Zadnik, Vesna, Zakham, Fathiah, Zaki, Nazar, Zakzuk, Josefina, Zamagni, Giulia, Zaman, Sojib Bin, Zandieh, Ghazal G Z, Zanghì, Aurora, Zar, Heather J, Zare, Iman, Zarimeidani, Fatemeh, Zastrozhin, Mikhail Sergeevich, Zeng, Youjie, Zhai, Chunxia, Zhang, Anthony Lin, Zhang, Haijun, Zhang, Liqun, Zhang, Meixin, Zhang, Yunquan, Zhang, Zhenyu, Zhang, Zhi-Jiang, Zhao, Hanqing, Zhao, Jeff T, Zhao, Xiu-Ju George, Zhao, Yang, Zhao, Yong, Zhong, Chenwen, Zhou, Jingjing, Zhou, Juexiao, Zhou, Shangcheng, Zhu, Bin, Zhu, Lei, Zhu, Zhaohua, Ziaeian, Boback, Ziafati, Makan, Zielińska, Magdalena, Zimsen, Stephanie R M, Zoghi, Ghazal, Zoller, Thomas, Zumla, Alimuddin, Zyoud, Sa'ed H, Zyoud, Samer H, Murray, Christopher J L, and Gakidou, Emmanuela
Published: 2024

36. Global fertility in 204 countries and territories, 1950-2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Author: V Bhattacharjee, N, E Schumacher, A, Aali, A, Habtegiorgis Abate, Y, Abbasgholizadeh, R, Abbasian, M, Abbasi-Kangevari, M, Abbastabar, H, Abd ElHafeez, S, Abd-Elsalam, S, Abdollahi, M, Abdollahifar, M, Abdoun, M, Abdullahi, A, Abebe, M, Shawel Abebe, S, Abiodun, O, Abolhassani, H, Abolmaali, M, Abouzid, M, Beressa Aboye, G, Guimarães Abreu, L, Aberhe Abrha, W, M Abrigo, M, Abtahi, D, Abualruz, H, Abubakar, B, Abu-Gharbieh, E, Me Abu-Rmeileh, N, Girum Girum Adal, T, Molla Adane, M, Atanda Adeagbo Adeagbo, O, Adesoji Adedoyin, R, Adekanmbi, V, Aden, B, Victor Adepoju, A, O Adetokunboh, O, Bunmi Adetunji, J, Adedayo Adeyinka, D, Israel Adeyomoye, O, Estiningtyas Sakilah Adnani, Q, Adra, S, Felix Afolabi, R, Afyouni, S, Sohail Afzal, M, Afzal, S, Aghamiri, S, Agodi, A, Agyemang-Duah, W, Opoku Ahinkorah, B, J Ahlstrom, A, Ahmad, A, Ahmad, D, Ahmad, F, M Ahmad, M, Ahmad, S, Ahmad, T, Ahmed, A, Ahmed, H, A Ahmed, L, Saleh Ahmed, M, Anees Ahmed, S, Ajami, M, Aji, B, Taddesse Akalu, G, Akbarialiabad, H, Olusola Akinyemi, R, Ahmed Akkaif, M, Akkala, S, Al Hamad, H, Mahfuz Al Hasan, S, Al Qadire, M, Mohammed Ali Al-Ahdal, T, O Alalalmeh, S, A Alalwan, T, Al-Aly, Z, Alam, K, Mustafa Al-Amer, R, Mashhour Alanezi, F, M Alanzi, T, Albakri, A, Albashtawy, M, T AlBataineh, M, Alemi, H, Alemi, S, Mulugeta Alemu, Y, Al-Eyadhy, A, Ali Saeed Al-Gheethi, A, F Alhabib, K, Alhajri, N, Alhalaiqa Naji Alhalaiqa, F, Kaba Alhassan, R, Ali, A, Abdulqadir Ali, B, Ali, L, Usman Ali, M, Ali, R, Shujait Shujait Ali, S, Mohammad Alif, S, Aligol, M, Alijanzadeh, M, M Aljasir, M, Mohamed Aljunid, S, Al-Marwani, S, Uy Almazan, J, M Al-Mekhlafi, H, Almidani, O, A Alomari, M, Al-Omari, B, S Alqahtani, J, Yaseen Alqutaibi, A, M Al-Raddadi, R, Khalifah Al-Sabah, S, Altaf, A, A Al-Tawfiq, J, A Altirkawi, K, Oyine Aluh, D, Jawad Alvi, F, Alvis-Guzman, N, Alwafi, H, Mohammed Al-Worafi, Y, Aly, H, Aly, S, H Alzoubi, K, Kwabena Ameyaw, E, Tawfik Amin, T, Amindarolzarbi, A, Amini-Rarani, M, Amiri, S, 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Bhageerathy Reshmi, Nazila Rezaei, Aida Rezaei Nejad, Mohsen Rezaeian, Abanoub Riad, Mavra A Riaz, Jennifer Rickard, Reza Rikhtegar, Hannah Elizabeth Robinson-Oden, Célia Fortuna Rodrigues, Jefferson Antonio Buendia Rodriguez, Ravi Rohilla, Debby Syahru Romadlon, Luca Ronfani, Himanshu Sekhar Rout, Bedanta Roy, Nitai Roy, Priyanka Roy, Enrico Rubagotti, Guilherme de Andrade Ruela, Susan Fred Rumisha, Tilleye Runghien, Manjula S, Chandan S N, Aly M A Saad, Zahra Saadatian, Maha Mohamed Saber-Ayad, Morteza SaberiKamarposhti, Siamak Sabour, Fatos Sada, Basema Saddik, Bashdar Abuzed Sadee, Ehsan Sadeghi, Erfan Sadeghi, Mohammad Reza Saeb, Umar Saeed, Sher Zaman Safi, Dominic Sagoe, Manika Saha, Amirhossein Sahebkar, Soumya Swaroop Sahoo, Monalisha Sahu, Zahra Saif, Joseph W Sakshaug, Payman Salamati, Afeez Abolarinwa Salami, Mohamed A Saleh, Marwa Rashad Salem, Mohammed Z Y Salem, Sohrab Salimi, Sara Samadzadeh, Yoseph Leonardo Samodra, Vijaya Paul Samuel, Abdallah M Samy, Juan Sanabria, Nima Sanadgol, Francesca Sanna, Milena M Santric-Milicevic, Haaris Saqib, Sivan Yegnanarayana Iyer Saraswathy, Aswini Saravanan, Babak Saravi, Yaser Sarikhani, Tanmay Sarkar, Rodrigo Sarmiento-Suárez, Gargi Sachin Sarode, Sachin C Sarode, Arash Sarveazad, Brijesh Sathian, Thirunavukkarasu Sathish, Anudeep Sathyanarayan, Abu Sayeed, Md Abu Sayeed, Nikolaos Scarmeas, Winfried Schlee, Art Schuermans, David C Schwebel, Falk Schwendicke, Siddharthan Selvaraj, Pallav Sengupta, Subramanian Senthilkumaran, Sadaf G Sepanlou, Dragos Serban, Edson Serván-Mori, Yashendra Sethi, SeyedAhmad SeyedAlinaghi, Seyed Arsalan Seyedi, Allen Seylani, Mahan Shafie, Jaffer Shah, Pritik A Shah, Ataollah Shahbandi, Samiah Shahid, Moyad Jamal Shahwan, Ahmed Shaikh, Masood Ali Shaikh, Muhammad Aaqib Shamim, Mehran Shams-Beyranvand, Mohammad Anas Shamsi, Mohd Shanawaz, Abhishek Shankar, Mohammed Shannawaz, Medha Sharath, Sadaf Sharfaei, Amin Sharifan, Javad Sharifi-Rad, Manoj Sharma, Rajesh Sharma, Ujjawal Sharma, Vishal Sharma, Rajesh P Shastry, Amin Shavandi, David H Shaw, Amir Mehdi Shayan, Maryam Shayan, Amr Mohamed Elsayed Shehabeldine, Aziz Sheikh, Rahim Ali Sheikhi, Manjunath Mala Shenoy, Pavanchand H Shetty, Peilin Shi, Desalegn Shiferaw, Mika Shigematsu, Rahman Shiri, Reza Shirkoohi, Aminu Shittu, Velizar Shivarov, Farhad Shokraneh, Sina Shool, Seyed Afshin Shorofi, Kanwar Hamza Shuja, Kerem Shuval, Emmanuel Edwar Siddig, João Pedro Silva, Luís Manuel Lopes Rodrigues Silva, Soraia Silva, Biagio Simonetti, Anjali Singal, Abhinav Singh, Balbir Bagicha Singh, Jasvinder A Singh, Md Shahjahan Siraj, Georgia Smith, Bogdan Socea, Anton Sokhan, Ranjan Solanki, Shipra Solanki, Hamidreza Soleimani, Sameh S M Soliman, Yonatan Solomon, Yimeng Song, Reed J D Sorensen, Michael Spartalis, Chandrashekhar T Sreeramareddy, Vijay Kumar Srivastava, Muhammad Haroon Stanikzai, Vladimir I Starodubov, Antonina V Starodubova, Simona Cătălina Stefan, Paschalis Steiropoulos, Mark A Stokes, Vetriselvan Subramaniyan, Muhammad Suleman, Rizwan Suliankatchi Abdulkader, Abida Sultana, Jing Sun, Chandan Kumar Swain, Bryan L Sykes, Lukasz Szarpak, Mindy D Szeto, Miklós Szócska, Payam Tabaee Damavandi, Rafael Tabarés-Seisdedos, Ozra Tabatabaei Malazy, Seyed-Amir Tabatabaeizadeh, Shima Tabatabai, Karen M Tabb, Mohammad Tabish, Moslem Taheri Soodejani, Jabeen Taiba, Ardeshir Tajbakhsh, Iman M Talaat, Ashis Talukder, Mircea Tampa, Jacques Lukenze Tamuzi, Ker-Kan Tan, Haosu Tang, Derbie Alemu DA Tareke, Mengistie Kassahun Tariku, Vivian Y Tat, Seyed Mohammad Tavangar, Mojtaba Teimoori, Mohamad-Hani Temsah, Reem Mohamad Hani Temsah, Masayuki Teramoto, Dufera Rikitu Terefa, Riki Tesler, Enoch Teye-Kwadjo, Ramna Thakur, Pugazhenthan Thangaraju, Kavumpurathu Raman Thankappan, Rekha Thapar, Samar Tharwat, Rasiah Thayakaran, Nihal Thomas, Ales Tichopad, Jansje Henny Vera Ticoalu, Tenaw Yimer Tiruye, Mariya Vladimirovna Titova, Marcello Tonelli, Marcos Roberto Tovani-Palone, Eugenio Traini, Jasmine T Tran, Nghia Minh Tran, Indang Trihandini, Samuel Joseph Tromans, Thien Tan Tri Tai Truyen, Aristidis Tsatsakis, Evangelia Eirini Tsermpini, Munkhtuya Tumurkhuu, Stefanos Tyrovolas, Sayed Mohammad Nazim Uddin, Aniefiok John Udoakang, Arit Udoh, Atta Ullah, Saeed Ullah, Sana Ullah, Srikanth Umakanthan, Chukwuma David Umeokonkwo, Brigid Unim, Bhaskaran Unnikrishnan, Era Upadhyay, Jibrin Sammani Usman, Marco Vacante, Seyed Mohammad Vahabi, Asokan Govindaraj Vaithinathan, Rohollah Valizadeh, Jef Van den Eynde, Elena Varavikova, Orsolya Varga, Priya Vart, Shoban Babu Varthya, Tommi Juhani Vasankari, Balachandar Vellingiri, Deneshkumar Venugopal, Nicholas Alexander Verghese, Madhur Verma, Massimiliano Veroux, Georgios-Ioannis Verras, Dominique Vervoort, Jorge Hugo Villafañe, Manish Vinayak, Francesco S Violante, Mukesh Vishwakarma, Sergey Konstantinovitch Vladimirov, Vasily Vlassov, Bay Vo, Simona Ruxandra Volovat, Theo Vos, Isidora S Vujcic, Hatem A Wafa, Yasir Waheed, Elias Bekele Wakwoya, Cong Wang, Denny Wang, Fang Wang, Shu Wang, Yanzhong Wang, Yuan-Pang Wang, Paul Ward, Emebet Gashaw Wassie, Stefanie Watson, Marcia R Weaver, Kosala Gayan Weerakoon, Daniel J Weiss, Katherine M Wells, Yi Feng Wen, Ronny Westerman, Taweewat Wiangkham, Dakshitha Praneeth Wickramasinghe, Nuwan Darshana Wickramasinghe, Peter Willeit, Yohannes Addisu Wondimagegene, Felicia Wu, Juan Xia, Hong Xiao, Gelin Xu, Suowen Xu, Xiaoyue Xu, Ali Yadollahpour, Shirin Yaghoobpoor, Tina Yaghoobpour, Sajad Yaghoubi, Zwanden Sule Yahaya, Danting Yang, Lin Yang, Yuichiro Yano, Habib Yaribeygi, Pengpeng Ye, Renjulal Yesodharan, Subah Abderehim Yesuf, Saber Yezli, Amanuel Yigezu, Paul Yip, Dong Keon Yon, Naohiro Yonemoto, Yuyi You, Mustafa Z Younis, Zabihollah Yousefi, Chuanhua Yu, Yong Yu, Chun-Wei Yuan, Nima Zafari, Fathiah Zakham, Nazar Zaki, Giulia Zamagni, Milad Zandi, Ghazal G Z Zandieh, Moein Zangiabadian, Mikhail Sergeevich Zastrozhin, Haijun Zhang, Meixin Zhang, Yunquan Zhang, Chenwen Zhong, Juexiao Zhou, Bin Zhu, Lei Zhu, Magdalena Zielińska, Zhiyong Zou, Samer H Zyoud, Christopher J L Murray, Amanda E Smith, and Stein Emil Vollset
Abstract: Background: Accurate assessments of current and future fertility-including overall trends and changing population age structures across countries and regions-are essential to help plan for the profound social, economic, environmental, and geopolitical challenges that these changes will bring. Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality, and family planning and support. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 produced up-to-date and comprehensive demographic assessments of key fertility indicators at global, regional, and national levels from 1950 to 2021 and forecast fertility metrics to 2100 based on a reference scenario and key policy-dependent alternative scenarios. Methods: To estimate fertility indicators from 1950 to 2021, mixed-effects regression models and spatiotemporal Gaussian process regression were used to synthesise data from 8709 country-years of vital and sample registrations, 1455 surveys and censuses, and 150 other sources, and to generate age-specific fertility rates (ASFRs) for 5-year age groups from age 10 years to 54 years. ASFRs were summed across age groups to produce estimates of total fertility rate (TFR). Livebirths were calculated by multiplying ASFR and age-specific female population, then summing across ages 10-54 years. To forecast future fertility up to 2100, our Institute for Health Metrics and Evaluation (IHME) forecasting model was based on projections of completed cohort fertility at age 50 years (CCF50; the average number of children born over time to females from a specified birth cohort), which yields more stable and accurate measures of fertility than directly modelling TFR. CCF50 was modelled using an ensemble approach in which three sub-models (with two, three, and four covariates variously consisting of female educational attainment, contraceptive met need, population density in
Published: 2024

37. Claudin 18.2 expression in digestive neuroendocrine neoplasms: a clinicopathological study

Author: Jiang, K., primary, Cao, F., additional, Yin, L., additional, Hu, Y., additional, Zhao, X., additional, Huang, X., additional, Ma, X., additional, Li, J., additional, Lu, M., additional, and Sun, Y., additional
Published: 2023
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38. Performance evaluation of transcritical CO2 desiccant heat pumps for electric vehicles

Author: Wang, H, primary, Song, Y, additional, Cao, F, additional, Rossi di Schio, E, additional, and Valdiserri, P, additional
Published: 2023
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39. Risk predicting for acute coronary syndrome with conventional and unstable plaque radiomics features from serial coronary computed tomography angiography

Author: Sun, T I N G, primary, Cao, F, additional, Gao, S, additional, Wang, Y B, additional, Li, A N G, additional, Wang, X J, additional, Fang, Y, additional, Fang, Z Y, additional, and Li, S L, additional
Published: 2023
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40. Banana Peel-Derived Dendrite-Shaped Au Nanomaterials with Dual Inhibition Toward Tumor Growth and Migration

Author: Liu Y, Song X, Cao F, Li F, Wang M, Yang Y, Liu M, Liu A, Xin H, and Wang X
Subjects: nanomaterials, au nanoparticles, biocompatibility, Medicine (General), R5-920
Abstract: Yu Liu,1,* Xiangwei Song,2,* Fei Cao,3 Fengshun Li,3 Manyu Wang,3 Yalan Yang,3 Mingzhuo Liu,4 Anwen Liu,1 Hongbo Xin,3 Xiaolei Wang2,3 1Department of Oncology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, People’s Republic of China; 2College of Chemistry, Nanchang University, Nanchang 330038, People’s Republic of China; 3Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330038, People’s Republic of China; 4Department of Burns, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaolei WangInstitute of Translational Medicine, Nanchang University, Hong Gu Tan New District, 1299 Xuefu Road, Nanchang 330088, People’s Republic of ChinaTel +86 18679850415Email wangxiaolei@ncu.edu.cnPurpose: In order to prepare functional Au nanoparticles with low toxicity and high antitumor properties, we have used fruit waste (banana peel) to synthesize a new dendrite-shaped gold nanoparticle and used it for the treatment of tumors.Methods: Dendrite-shaped gold nanoparticle (Au-dendrite) was synthesized through a facile hydrothermal process. The banana peel was used as both the reducing agent and the protective agent for reducing chloroauric acid to obtain Au-dendrite. The safety assessment of the Au-dendrite was conducted by H&E staining of the mouse’s eyelid skin and CCK-8 assay. The antitumor effects were evaluated through in vitro tumor cytotoxicity experiments and in vivo treatment of animal tumors.Results: In this work, a new type of gold nanomaterial (Au-dendrite) was synthesized by using a common agricultural waste (banana peel) through a facile hydrothermal process without any extra chemical reducing agent or protective agent. Subsequent experiments showed that, compared with some classical Au nanomaterials, the as-synthesized gold nanocomposites have superior biocompatibility and impressive characteristics of dual inhibition toward tumor growth and migration.Conclusion: We successfully synthesized a dendrite-shaped gold nanocomposite which was derived from a common agricultural waste (banana peel). A facile and environmentally friendly synthetic process was proposed accordingly without regular chemical additives. The as-prepared Au-dendrite nanocomposites not only had better biocompatibility than some classical gold nanoparticles but also exhibited unique advantages in tumor inhibition.Keywords: nanomaterials, Au nanoparticles, biocompatibility
Published: 2020

41. A Peptide-Functionalized Magnetic Nanoplatform-Loaded Melatonin for Targeted Amelioration of Fibrosis in Pressure Overload-Induced Cardiac Hypertrophy

Author: Zhao X, Wang X, Wang J, Yuan J, Zhang J, Zhu X, Lei C, Yang Q, Wang B, Cao F, and Liu L
Subjects: magnetic targeting, cardiac homing peptide, cardiac hypertrophy, melatonin, myocardial fibrosis., Medicine (General), R5-920
Abstract: Xueli Zhao,1 Xuanying Wang,1 Jing Wang,1 Jiani Yuan,1 Juan Zhang,1 Xiaoli Zhu,1 Changhui Lei,1 Qianli Yang,1 Bo Wang,1 Feng Cao,2 Liwen Liu1 1Department of Ultrasound of Xijing Hospital, Xijing Hypertrophic Cardiomyopathy Center, Fourth Military Medical University, Xi’an 710032, People’s Republic of China; 2Department of Cardiology, Chinese PLA General Hospital, Beijing 100700, People’s Republic of ChinaCorrespondence: Liwen Liu Email liuliwen@fmmu.edu.cnIntroduction: Currently, the unsatisfactory treatment of cardiac hypertrophy is due to the unbridled myocardial fibrosis. Melatonin has been demonstrated to ameliorate cardiac hypertrophy and its accompanied fibrosis in previous studies. But it is not clinically appealing due to its short-lasting time against the hostile microenvironment when administered orally.Methods: Herein, to address this, poly (lactide) polycarboxybetaine (PLGA-COOH) accompanied by cardiac homing peptide (CHP) and superparamagnetic iron oxide nanoparticles (SPIONs) were used to establish a novel drug delivery and transportation strategy for melatonin via a facile two-step emulsion method. This study characterized these nanoparticles (CHP-mel@SPIONs) and tested their delivery to the hypertrophied heart and their effect on myocardial hypertrophy and fibrosis in an animal model of pressure overload-induced cardiac hypertrophy.Results: The engineered magnetic nanoparticles of CHP-mel@SPIONs were spherical (diameter = 221 ± 13 nm) and had a negative zeta potential of − 19.18 ± 3.27 mV. The CHP-mel@SPIONs displayed excellent drug encapsulation capacities of SPIONs (75.27 ± 3.1%) and melatonin (77.69 ± 6.04%) separately, and their magnetic properties were characterized by constructing magnetic hysteresis curves and exhibited no remnant magnetization or coercivity. The animal experiments showed that compared with mel@SPIONs, CHP-mel@SPIONs accumulated more in the heart, especially in the presence of an external magnetic field, with in vivo echocardiography and RT-PCR and histological assessments confirming the amelioration of the myocardial hypertrophy and fibrosis with low drug doses.Conclusion: This simple biocompatible dual-targeting nanoagent may be a potential candidate for the guided clinical therapy of heart disease.Keywords: magnetic targeting, cardiac homing peptide, cardiac hypertrophy, melatonin, myocardial fibrosis
Published: 2020

42. Efficacy Of Apatinib In Transcatheter Arterial Chemoembolization (TACE) Refractory Intermediate And Advanced-Stage Hepatocellular carcinoma：A Propensity Score Matching Analysis

Author: Qiu Z, Shen L, Chen S, Qi H, Cao F, Xie L, and Fan W
Subjects: hepatocellular carcinoma, transarterial chemoembolization, apatinib, prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Zhiyu Qiu,1,2,* Lujun Shen,1,3,* Shuanggang Chen,1,3,* Han Qi,1,3 Fei Cao,1,3 Lin Xie,1,3 Weijun Fan1,3 1Department of Minimally Invasive Interventional Therapy, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, People’s Republic of China; 2Zhong Shan Medical School, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China; 3State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weijun FanDepartment of Minimally Invasive Interventional Therapy, Sun Yat-sen University Cancer Center, No. 651 Dongfeng East Road, Guangzhou, Guangdong 510060, People’s Republic of ChinaTel/fax +86 20 8734 3272Email fanwj@sysucc.org.cnPurpose: This research aimed to compare the efficacy of combination treatment of transcatheter arterial chemoembolization (TACE) with apatinib versus TACE-alone for intermediate and advanced-stage hepatocellular carcinoma (HCC) cases refractory to TACE.Patients and methods: A total of 125 patients with TACE refractory intermediate or advanced-stage HCC were enrolled and classified as TACE-apatinib group and TACE-alone group. One-to-one matched pairs between two groups were generated using propensity score matching (PSM). Associations of treatment modality with overall survival (OS) and progression-free survival (PFS) were determined by Cox regression. Adverse effects (AEs) were compared between two treatment groups to assess the safety of apatinib.Results: Before PSM analysis, the median OS and PFS were 17.0 and 7.0 months in the TACE-apatinib group, while 8.5 and 2.5 months in the TACE-alone group (P
Published: 2019

43. Global Burden of Cardiovascular Diseases and Risks, 1990-2022

Author: Mensah, G, Fuster, V, Murray, C, Roth, G, Abate, Y, Abbasian, M, Abd-Allah, F, Abdollahi, A, Abdollahi, M, Abdulah, D, Abdullahi, A, Abebe, A, Abedi, A, Abiodun, O, Ali, H, Abu-Gharbieh, E, Abu-Rmeileh, N, Aburuz, S, Abushouk, A, Abu-Zaid, A, Adane, T, Adderley, N, Adebayo, O, Aden, B, Adeyeoluwa, T, Adeyomoye, O, Sakilah Adnani, Q, Afrashteh, F, Afyouni, S, Afzal, S, Agasthi, P, Agodi, A, Aguilera Arriagada, C, Agyemang-Duah, W, Ahinkorah, B, Ahmad, A, Ahmad, D, Ahmad, F, Ahmad, M, Ahmed, A, Ahmed, H, Ahmed, M, Ahmed, S, Ajami, M, Akinosoglou, K, Ala, M, Ali AL-Ahdal, T, Alalalmeh, S, Al-Aly, Z, Alam, N, Al-amer, R, Alashi, A, Albashtawy, M, Albataineh, M, Alema, H, Alemi, S, Alemu, Y, Saeed Al-Gheethi, A, Alhabib, K, Naji Alhalaiqa, F, Ali, M, Ali, R, Pursuing, P, Shujait Ali, S, Alicandro, G, Alikhani, R, Aljunid, S, Alla, F, Almahmeed, W, Al-Marwani, S, Alonso, J, Al-Raddadi, R, Alvi, F, Alvis-Guzman, N, Alvis-Zakzuk, N, Alwafi, H, Aly, H, Amegbor, P, Amin, T, Amindarolzarbi, A, Amini-Rarani, M, Amiri, S, Ammirati, E, Anand, T, Ancuceanu, R, Anderlini, D, Anil, A, Ansari, G, Anyanwu, P, Anyasodor, A, Carace Apostol, G, Arabloo, J, Arafat, M, Aravkin, A, Aremu, O, Armocida, B, Arnlov, J, Arowosegbe, O, Artamonov, A, Artanti, K, Arulappan, J, Aruleba, I, Arumugam, A, Aryan, Z, Asghari-Jafarabadi, M, Astell-Burt, T, Ataei, M, Athar, M, Atreya, A, Aujayeb, A, Awotidebe, A, Aynalem, A, Azizi, Z, Azzam, A, Babu, A, Badar, M, Bader, F, Badiye, A, Bagga, A, Bagherieh, S, Asl, F, Bai, R, Baker, J, Bakkannavar, S, Bako, A, Bakshi, R, Balogun, S, Baltatu, O, Bam, K, Banach, M, Bandyopadhyay, S, Banik, B, Chandra Banik, P, Bansal, K, Baradaran, H, Barbic, F, Barchitta, M, Bardhan, M, Barker-Collo, S, Barnighausen, T, Barone-Adesi, F, Barteit, S, Barua, L, Bashiri, A, Bayati, M, Bayileyegn, N, Behboudi, E, Behnoush, A, Bejot, Y, Belay, S, Belete, M, Belgaumi, U, Bell, M, Belo, L, Bendak, S, Benfor, B, Bennett, D, Bensenor, I, Benziger, C, Beran, A, 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O, Dai, X, Dai, Z, Dalaba, M, Moura Damasceno, A, Damiani, G, D'Amico, E, Das, S, Dashti, M, Dashtkoohi, M, Dastmardi, M, Davletov, K, Debele, A, Debopadhaya, S, Decleene, N, Delgado-Enciso, I, Delgado-Saborit, J, Demessa, B, Demetriades, A, Deng, X, Denova-Gutierrez, E, Dereje, N, Asrat Derese, A, Desai, H, Desai, R, Chellaiyan Devanbu, V, Rahman Dewan, S, Dey, S, Dhulipala, V, Diaz, D, Diaz, M, Ding, D, Dinis-Oliveira, R, Do, T, Phuong Do, T, Doaei, S, Dohare, S, Dong, W, D'Oria, M, Mombaque dos Santos, W, Douiri, A, Dowou, R, Dsouza, A, Dsouza, H, Dsouza, V, Du, M, Duraes, A, Durojaiye, O, Dutta, S, Dziedzic, A, Ebrahimi, A, Efendi, D, Efendi, F, Effendi, D, Eini, E, Ekholuenetale, M, Ekundayo, T, El Sayed, I, El Tantawi, M, Elbarazi, I, Elgar, F, Elgendy, I, Elhadi, M, El-Huneidi, W, Emamverdi, M, Emeto, T, Erkhembayar, R, Eshetie, T, Espinosa-Montero, J, Etaee, F, Fabin, N, Fadhil, I, Fagbamigbe, A, Falzone, L, Sofia e Sa Farinha, C, Faris, M, Faro, A, Faruque, M, Farwati, M, 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T., Lallukka T., Lan Q., Landires I., Lanfranchi F., Larijani B., Larsson A. O., Lasrado S., Latief Epidemiology K., Latifinaibin K., Lau J., Lauriola P., Le K., Dao Le L. K., Hanh Le N. H., Thu Le T. T., Thanh Le T. D., Bich Le T. T., Ledda C., Lee M., Lee P. H., Lee S. W., Lee W. -C., Lee Y. H., LeGrand K. E., Leinsalu M., Leonardi M., Lerango T. L., Li A., Li M. -C., Li W., Li X., Li Y., Lim L. -L., Lim S. S., Lin R. -T., Lindstrom M., Linn S., Liu G., Liu S., Liu X., Livingstone K. M., Llanaj E., Lopukhov P. D., Sci (Med) C. O., Loreche A. M., Lorenzovici L., Lorkowski S., Lotufo P. A., Lucchetti G., Lugo A., Ma Z. F., Madadizadeh F., Maddison R., Magana Gomez J. A., Magne J., Prasad D. R. M., Mahalleh M., Mahmoud M. A., Mahmoudi E., Mahmoudvand B., Makram O. M., Rad E. M., Malekzadeh R., Malhotra K., Malik I., Ahmed Malik M. S., Mallhi T. H., Malta D. C., Manilal A., Manla Y., Mansoori Y., Mansouri B., Mansouri P., Mansournia M. A., Marateb H. R., Marino M., Martini D., Martini S., Maryam S., Marzo R. R., Masoudi A., Masoudi S., Matei C. N., Mathangasinghe Y., Mathews E., Mathur M. R., Mattumpuram J., Maude R. J., Maugeri A., Mayeli M., Mazidi M., McGrath J. J., McPhail S. M., Mechili E. A., Carabeo Medina J. R., Meena J. K., Mehrabani-Zeinabad K., Mendez Mendez-Lopez M. A., Mendoza W., Menezes R. G., Mengist B., Meo S. A., Meresa H. A., Meretoja A., Meretoja T. J., Mestrovic T., Dinushi Mettananda K. C., Mettananda S., Mhlanga L., Mi T., Jonasson J. M., Miazgowski T., Michalek I. M., Miller T. R., Nhat Minh L. H., Minja N. W., Mohammad Sadeghi P. M., Mirdamadi N., Mirica A., Mirrakhimov E. M., Mirza M., Mirza-Aghazadeh-Attari M., Mithra P., Moghimi Z., Mohamed J., Mohamed M. F. H., Mohamed N. S., Mohammadi S., Mohammed H., Mohammed M., Mohammed S., Moka N., Mokdad A. H., Vardanjani H. M., Momtazmanesh S., Monasta L., Montazeri F., Ghalibaf A. M., Moradi Y., Moraga P., Morawska L., Morovatdar N., Morrison S. D., Morze J., Mostafavi E., Mostofinejad A., Mougin V., Mousavi P., Mousavi S. E., Mozaffarian D., Msherghi A., Muccioli L., Mueller U. O., Mukherjee S., Munjal K., Murillo-Zamora E., Mustafa G., Muthu S., Mwita J. C., Myung W., Nagarajan A. J., Nagaraju S. P., Naik G. R., Naik G., Nair T. S., Najafi M. S., Ansari N. N., Nangia V., Swamy S. N., Nargus S., Nascimento B. R., Nascimento G. G., Nasoori H., Natto Z. S., Nauman J., Naveed M., Nayak B. P., Nayak V. C., Negash H., Negoi I., Negoi R. I., Shahrokh Abadi R. N., Nejadghaderi S. A., Nejjari C., Nematollahi M. H., Nepal S., Ng N., Nguyen D. H., Nguyen P. T., Nguyen V. T., Niazi R. K., Nijjar S. S., Nizam M. A., Noman E. A., Nomura S., Noreen M., Norrving B., Noubiap J. J., Nri-Ezedi C. A., Ntsekhe M., Nurrika D., Nzoputam C. I., Nzoputam O. J., Obamiro K. O., O'Donnell M. J., Oghenetega O. B., Oguntade A. S., Oguta J. O., Okeke S. R., Okekunle A. P., Okidi L., Okonji O. C., Okwute P. G., Olagunju A. T., Olaiya M. T., Olana M. D., Olatubi M. I., Moraes Oliveira G. M., Olorukooba A. A., Olufadewa I. I., Oluwafemi Y. D., Oluwatunase G. O., Omer G. L., Ommati M. M., Ong K. L., Ong S., Onyedibe K. I., Ordak M., Ortega-Altamirano D. V., Ortiz A., Ortiz-Prado E., Osman W. M. S., Osuagwu U. L., Otoiu A., Otstavnov S. S., Owolabi M. O., Padukudru P A M., Padron-Monedero A., Padubidri J. R., Varnosfaderani M. P., Palicz T., Palladino R., Pan F., Pan H. -F., Pandi-Perumal S. R., Papadopoulou P., Park S., Passera R., Patel J., Patil S., Patoulias D., Patthipati V. S., Pawar S., Peden A. E., Pedersini P., Peng M., Filipino Pepito V. C., Peprah E. K., Pereira M., Pereira M. O., Peres M. F. P., Perianayagam A., Perico N., Petermann-Rocha F. E., Pham H. T., Philip A. K., Pigott D. M., Pilgrim T., Piradov M. A., Plotnikov E., Poddighe D., Polibin R. V., Poluru R., Pourali G., Pourshams A., Singh Pradhan P. M., Prasad M., Sady Prates E. J., Purohit B. M., Puvvula J., Qattea I., Qian G., Qureshi M. F., Rabiee rad M., Radfar A., Rafiei Alavi S. N., Rafique I., Raggi A., Rahim F., Rahim M. J., Rahimi M., Rahman M., Rahman M. A., Rahmani A. M., Rahmani B., Rahmani S., Rahmanian V., Rai P., Rajaa S., Rajabpour-Sanati A., Rajput P., Ram P., Ramalingam S., Ramasamy S. K., Ramazanu S., Ramesh P. S., Rana J., Rana K., Ranabhat C. L., Rancic N., Rane A., Ranjan S., Ranta A., Rao I. R., Rao M., Rao S. J., Rashedi S., Rashedi V., Rashid A. M., Rasul A., Ratan Z. A., Babu G. R., Ravikumar N., Rawaf S., Razeghian-Jahromi I., Razo C., Rama Krishna Reddy M. M., Mohamed Redwan E. M., Remuzzi G., Reyes L. F., Rezaei N., Rezaeian M., Ribeiro A. L. P., Ribeiro D., Rikhtegar R., Roever L., Romadlon D. S., Ronfani L., Sekhar Rout H. S., Roy N., Roy P., Rynkiewicz A., Saad A. M. A., Saadatian Z., Sabour S., Sacco S., Sachdeva R., Saddik B., Sadeghi E., Saeed U., Safaeinejad F., Sharif-Askari F. S., Sharif-Askari N. S., Sahebkar A., Sahoo S. S., Sajedi S. A., Sajid M. R., Sakshaug J. W., Salam N., Salami A. A., Saleh M. A., Salehi S., Salem M. R., Salem M. Z. Y., Samadzadeh S., Samargandy S., Samuel V. P., Samy A. M., Sanabria J., Sanjeev R. K., Santric-Milicevic M. M., Nadeem Saqib M. A., Sarasmita M. A., Saravanan A., Sarikhani Y., Sarkar T., Sarmiento-Suarez R., Sarode G. S., Sarode S. C., Sathish T., Sathyanarayan A., Sawhney M., Sayyah M., Scarmeas N., Schaarschmidt B. M., Schuermans A., Schumacher A. E., Schutte A. E., Schwebel D. C., Sedighi M., Seidu A. -A., Semnani F., Senapati S., Sengupta P., Senthilkumaran S., Sepanlou S. G., Sethi Y., Seyedi S. A., Seylani A., Shabany M., Shafeghat M., Shafie M., Shah P. A., Shahbandi A., Shahid I., Shahid S., Shahid W., Shahwan M. J., Shaikh M. A., Sham S., Shamim M. A., Shanawaz M., Sharfaei S., Sharifan A., Sharifi-Rad J., Sharma P., Sharma S., Sharma U., Sharma V., Sheikh A., Shiferaw D. S., Shigematsu M., Shin M. -J., Shiri R., Shishani K., Shittu A., Shiue I., Shivakumar K. M., Shrestha S., Shuval K., Sibhat M. M., Sigfusdottir I. D., Simpson C. R., Singh A., Singh J. A., Singh P., Singh R., Singh S., Siraj M. S., Skryabin V. Y., Skryabina A. A., Sleet D. A., Soleimani H., Solikhah S., Soliman S. S. M., Son J., Song S., Song Y., Soriano J. B., Spartalis M., Sreeramareddy C. T., Stafford L. K., Stark B. A., Steiropoulos P., Stortecky S., Abdulkader R. S., Sultana A., Sundstrom J., Swain C. K., Damavandi P. T., Tabatabaei S. M., Malazy O. T., Tabatabaeizadeh S. -A., Tabatabai S., Tabb K. M., Tabish M., Tabuchi T., Tadese F., Abkenar Y. T., Taiba J., Talaat I. M., Tampa M., Lukenze Tamuzi J. J. L., Tan K. -K., Tang H., Tarkang E. E., Tat N. Y., Tavangar S. M., Tehrani H., Teimoori M., Temsah M. -H., Hani Temsah R. M., Teramoto M., Thangaraju P., Thankappan K. R., Thapa R., Thapar R., Thavamani A., Thayakaran R., Thomas N. K., Tian J., Tichopad A., Tillawi T., Tonelli M., Topor-Madry R., Touvier M., Tovani-Palone M. R., Tran J. T., Tran N. M., Van Tran P., Trihandini I., Tripathi A., Tromans S. J., Truong V. T., Tri Tai Truyen T. T., Tsatsakis A., Tsegay G. M., Tsermpini E. E., Tumurkhuu M., Tung K., Ubah C. S., Udoakang A. J., Udoh A., Ullah A., Ullah S., Umair M., Umar T. P., Unim B., Unnikrishnan B., Upadhyay E., Usman J. S., Vahabi S. M., Vaithinathan A. G., Valizadeh R., Van den Eynde J., Varga O., Varma S. A., Vart P., Varthya S. B., Vasankari T. J., Vellingiri B., Vervoort D., Villafane J. H., Violante F. S., Viskadourou M., Volovat S. R., Vos T., Vujcic I. S., Wafa H. A., Wahab F., Wang C., Wang F., Wang N., Wang S., Wang Y., Wang Y. -P., Wei M. Y., Werdecker A., Wickramasinghe N. D., Wijeratne T., Wilandika A., Wilson S., Wolfe C. D. A., Wongsin U., Wu Z., Xiao H., Xu S., Xu X., Yadav L., Yano Y., Yaribeygi H., Yasufuku Y., Nia I. Y., Ye P., Yesuf S. A., Yezli S., Yigit A., Yigit V., Yilma M. T., Yon D. K., Yonemoto N., Yousefi Z., Yperzeele L., Yu C., Yunusa I., Zafari N., Tajrishi F. Z., Zakham F., Zastrozhin M. S., Zeineddine M. A., Zemedikun D. T., Zeng Y., Zhai C., Zhang C., Zhang H., Zhang L., Zhang N., Zhang Y., Zhao H., Zheng P., Zhong C., Zhou S., Zhu B., Zhu L., Zielinska M., Zikarg Y. T., Zmaili M., Zoeckler L. Z., Zou Z., Zumla A., Zweck E., and Zyoud S. H.
Published: 2023

44. A comprehensive experimental study on temperature-dependent performance of lithium-ion battery

Author: Lu, Z., Yu, X.L., Wei, L.C., Cao, F., Zhang, L.Y., Meng, X.Z., and Jin, L.W.
Published: 2019
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45. Open Problems on Information and Feedback Controlled Systems

Author: Cao, F. J. and Feito, M.
Subjects: Condensed Matter - Statistical Mechanics
Abstract: Feedback or closed-loop control allows dynamical systems to increase their performance up to a limit imposed by the second law of thermodynamics. It is expected that within this limit, the system performance increases as the controller uses more information about the system. However, despite the relevant progresses made recently, a general and complete formal development to justify this statement using information theory is still lacking. We present here the state-of-the-art and the main open problems that include aspects of the redundancy of correlated operations of feedback control and the continuous operation of feedback control. Complete answers to these questions are required to firmly establish the thermodynamics of feedback controlled systems. Other relevant open questions concern the implications of the theoretical results for the limitations in the performance of feedback controlled flashing ratchets, and for the operation and performance of nanotechnology devices and biological systems., Comment: LaTeX, 10 pages, 2 figures. Improved version to appear in Entropy
Published: 2012
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46. Strange sea distributions of the nucleon

Author: Chen, H., Cao, F. -G., and Signal, A. I.
Subjects: High Energy Physics - Phenomenology, Nuclear Theory
Abstract: The strange and antistrange quark distributions of the nucleon are less constrained by experimental data than the non-strange quark sea. The combination of light quark sea distributions, $\Delta(x)=\dbar(x)+\ubar(x)-s(x)-\sbar(x)$, originates mainly from non-perturbative processes and can be calculated using non-perturbative models of the nucleon. We have calculated $\Delta(x)$ using the meson cloud model, which, when combined with the relatively well known non-strange light antiquark distributions obtained from global analysis of available experimental data, enables us to make new estimates of the total strange sea distributions of the nucleon and the strange sea suppression factor., Comment: version published in J. Phys. G, 14 pages, 3 figures
Published: 2009
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47. Rocking feedback controlled ratchets

Author: Feito, M., Baltanas, J. P., and Cao, F. J.
Subjects: Condensed Matter - Other Condensed Matter
Abstract: We investigate the different regimes that emerge when a periodic driving force, the rocking force, acts on a collective feedback flashing ratchet. The interplay of the rocking and the feedback control gives a rich dynamics with different regimes presenting several unexpected novel features. In particular, we show that for both the one-particle ratchet and the collective version of the ratchet an appropriate rocking increases the flux. This mechanism gives the maximum flux that has been achieved in a ratchet device without an a priori bias., Comment: LaTeX, 8 pages, 8 figures. To appear in Phys. Rev. E
Published: 2009
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48. Nickel nanoparticles activated highly porous carbon for excellent sodium storage

Author: Pan, G.X., Cao, F., Xie, D., Zhang, Y.J., and Xia, X.H.
Published: 2018
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49. 1004P Comparative efficacy of systemic sequential regorafenib after sorafenib or lenvatinib treatment failure for advanced hepatocellular carcinoma: A retrospective, multi-center, real-world study

Author: Song, D., primary, Zheng, L., additional, Zhang, A., additional, Cao, F., additional, Hao, W., additional, Zhao, Z., additional, Zheng, J., additional, and Lu, D., additional
Published: 2023
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50. ALPHA-BLOCKERS COMBINED WITH BETA-3 AGONISTS FOR TREATING LOWER URINARY TRACT SYMPTOMS RELATED TO BENIGN PROSTATIC OBSTRUCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS

Author: Chen, Y, primary, Cao, F, additional, and Pang, R, additional
Published: 2023
Full Text: View/download PDF

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