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Major Depressive Disorder (MDD) may exhibit impairments in cognitive flexibility. This study investigated whether the cognitive flexibility deficits in MDD are evident across general stimuli or specific to emotional stimuli, while exploring the underlying neuropsychological mechanism. A total of 41 MDD patients and 42 healthy controls (HCs) were recruited. Event-related potentials (ERPs) were recorded when participants performed a non-emotional and an emotional task switching paradigm (N-ETSP and ETSP), both of which assessed cognitive flexibility. Microstate and source localization analysis were applied to reflect brain activity among different brain areas during task switching. In the N-ETSP, MDD group showed larger P3 difference wave (Pd3) amplitudes and longer P2 difference wave (Pd2) latencies. In the ETSP, MDD group displayed smaller N2 difference wave (Nd2) amplitudes and larger Pd3 amplitudes. The comparison of sLORETA images of emotional switch task and emotional repeat task showed that MDD group had increased activation in the precentral gyrus in microstate2 of the P2 time window and had reduced activation in the middle occipital gyrus in microstate3 of the N2 time window. The cross-sectional design failed to capture dynamic changes in cognitive flexibility in MDD. MDD demonstrated impaired cognitive flexibility respond to both non-emotional and emotional stimuli, with greater impairment for negative emotional stimuli. These deficits are evident in abnormal ERPs component during the early attention stage and the later task preparation stage. Furthermore, abnormal emotional switching cost in MDD appears to be related to early abnormal perceptual control in the parietal-occipital cortex. • MDD exhibited impaired cognitive flexibility in general and negative stimuli. • Higher emotional switching cost of error rate, the lower brain activation in MDD. • MDD showed the abnormal early perceptual control in the parietal-occipital cortex. [ABSTRACT FROM AUTHOR]

Objective: Cognitive flexibility, identified as a transdiagnostic process in psychopathology, lacks specific Spanish-validated assessment tools. This study aims to examine the psychometric properties of the Cognitive Flexibility Inventory in a Spanish sample (N = 300, mean age = 22.66, SD = 4.92), 76% women). Method: An exploratory structural equation model (ESEM) was used to test the inventory's latent structure. Reliability was calculated, as well as construct validity evidence with measures of emotion regulation, attributional style, and depression. Results: The original bifactorial model of the Cognitive Flexibility Inventory (Alternatives and Control scales) was replicated and obtained good fit indices. One item was excluded due to problematic factor loadings, yielding a final version with 19 items. Evidence of validity and reliability was obtained. Conclusions: The Spanish version of the Cognitive Flexibility Inventory showed satisfactory psychometric properties, making it a suitable measure for the assessment of cognitive flexibility in the Spanish population. [ABSTRACT FROM AUTHOR]

Vaccine hesitancy has gained heightened relevance amid the COVID-19 pandemic, underscoring the urgency of understanding its determinants. This study explores the association between Covid-19 vaccine hesitancy, mental health variables and inflexible thinking. A convenience sample of 252 UK adults was assessed online between June 2021–July 2022 (when Covid-19 lockdown restrictions had finally eased). We assessed participants using the Oxford Covid Vaccine Hesitancy Scale (OCVHS), various aspects of mental health, using: the Obsessive-Compulsive Inventory-Revised (OCI-R), Compulsive Personality Assessment Scale (CPAS), Depression, Anxiety, and Stress scale (DASS-21), and finally, performance on a computerized version of the Wisconsin Card Sort Task (WCST). This study was preregistered at the Open Science Framework (https://osf.io/xd5wz). Multiple regression analyses showed that only cognitive inflexibility, and specifically the WCST item of perseverative errors, significantly predicted vaccine hesitancy. Our exploratory analysis provides the first evidence that cognitive inflexibility, measured using an objective task, is an independent risk-factor for vaccine hesitancy. Public health strategies should consider the impact of an inflexible thinking style on the decision-making of those most at risk of vaccine hesitancy and adapt interventions accordingly. [ABSTRACT FROM AUTHOR]

The purpose of the present study was to compare executive functions in people with high and low resilience. Based on the results of a structured clinical interview and Connor- Davidson resilience Scale (CD-RISC), a total of 140 adults were assigned to high resilience (n = 70) and low resilience (n = 70) groups. Working memory, inhibition and cognitive flexibility were assessed by N-Back, Go/No-Go and Wisconsin Card Sorting task, respectively. The results showed that individuals with high resilience compared to individuals with low resilience scored significantly higher on inhibition and cognitive flexibility, but there were no significant differences on working memory. The current findings suggest a role of high-level cognitive processes in resilience, which in turn may contribute to mental health. Also, the results of this research may be important in the design of therapeutic interventions based on executive functions. • Individuals with high resilience compared to individuals with low resilience scored significantly higher on inhibition. • Individuals with high resilience compared to individuals with low resilience scored significantly cognitive flexibility. • There were no significant differences between individuals with high and low resilience on working memory. [ABSTRACT FROM AUTHOR]

The component structure of executive functioning (EF) has been shown to change across development. Empirical research examining this in Sub‐Saharan Africa is limited. We report the development of EF component structure with a large sample of Ghanaian children (n = 2,979) followed longitudinally from ages 3 through 12 across six waves. Existing literature suggests unitary models of EF (components loading onto a single factor) early in childhood, with development across childhood and into adolescence resulting in a more diversified EF model (components loading onto two‐ or three‐factors). To test these developmental differences, participants completed EF batteries that measured EF components: working memory, short‐term memory, inhibition, and cognitive flexibility/shifting. We employed confirmatory factor analysis to test factor models in 3‐ to 4‐year‐olds, 5‐ to 6‐year‐olds, 7‐ to 9‐year‐olds, and 10‐ to 12‐year‐olds. Contrary to existing literature, a two‐factor EF model best explained EF performance as early as 3–4 years of age. Findings suggest that diversification of EF components may emerge earlier in childhood than expected in some contexts, questioning the universality in the timing of unification and diversification of EF structure. [ABSTRACT FROM AUTHOR]

Purpose: Social workers navigate systemic stressors while managing self-care amid scant institutional support. The purpose of this systematic review is to critically examine the state of social work intervention research for self-care practices. Methods: This review includes empirical research articles focusing on self-care interventions in social work between 2011 and 2022 (N = 22). Results: All self-care interventions focused on modifying individual behaviors, attitudes, and knowledge. Discussion: Most (83%) research on self-care interventions focused on mindfulness, which tended to be associated with improvements in mindfulness, distress management, and clinical self-efficacy. The remaining interventions tended to be associated with improvements in self-care attitudes, knowledge, practices, and wellness. Conclusion: Structural factors and socioeconomic privilege have been found to be predominant predictors of whether social work students, educators, and practitioners engaged in self-care practices, yet no interventions incorporated structural or institutional variables. Multilevel interventions addressing structural, institutional, and relational determinants of burnout are needed. [ABSTRACT FROM AUTHOR]

Obstructive sleep apnea (OSA) is associated with the impairment of a range of cognitive functions. Whether treatment with continuous positive airway pressure (CPAP) improves these cognitive functions is still a matter of debate. We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) that included OSA patients (apnea hypopnea index, AHI >10/h), naive to CPAP treatment, with a cognitive assessment before and after CPAP initiation. We compared CPAP versus sham-CPAP or placebo tablet or dietary rules or no treatment. This systematic review and meta-analysis were registered in PROSPERO (ID CRD42021275214). Eleven RCTs encompassing 923 OSA patients were included. For most of them, CPAP initiation was ≤3 months. A significant post-treatment improvement was found for the Trail Making Test part B (TMT-B; SMD = -0.93, 95 % CI = [-1.60, −0.25], Z = −2.70, p = 0.007), but not for the other neuropsychological assessments. No global effects on other cognitive domains (information processing speed, executive functions, working memory) were found. The significant improvement in the TMT-B supports a short-term enhancement in cognitive flexibility with CPAP treatment. Further studies that take into account OSA comorbidities, cognitive profiles, a more diverse range of cognition assessments and include long-term evaluations are needed. [Display omitted] • CPAP improves cognitive flexibility in OSA. • Executive functions seem however not globally improved by CPAP. • We found no CPAP global effect on information processing speed and working memory. • Results highlight the heterogeneity of cognitive functioning among OSA patients. [ABSTRACT FROM AUTHOR]

Objective: The purpose of this study was to examine the effectiveness of emotional self-regulation skills training on cognitive flexibility and working memory among ninth-grade students in Jajrom. Methods and Materials: This quasi-experimental study employed a pre-test, post-test, and follow-up design with control and experimental groups. The statistical population comprised all ninth-grade students in Jajrom during the 2022-2023 academic year. A total of 60 students were selected through cluster sampling and randomly assigned to either the experimental group, which received emotional self-regulation skills training, or the control group, which did not receive any intervention. Data were collected using the Daneman and Carpenter (1980) Working Memory Test and the Dennis and Vander Wal (2010) Cognitive Flexibility Inventory. Data were analyzed using SPSS software and multivariate covariance analysis (MANCOVA). Findings: The results indicated that the experimental group showed significant improvements in emotional self-regulation skills, cognitive flexibility, and working memory from pre-test to post-test and follow-up stages. Specifically, the mean scores for emotional self-regulation skills increased from 74.7 to 99.4, cognitive flexibility from 69.3 to 79.1, and working memory from 57.6 to 80.2. In contrast, the control group did not exhibit any significant changes in these measures. Conclusion: The findings suggest that emotional self-regulation skills training significantly enhances cognitive flexibility and working memory among ninth-grade students. These improvements indicate that such training can be a valuable intervention to boost psychological flexibility and academic performance. The results align with previous studies, supporting the effectiveness of emotional self-regulation training in educational settings. [ABSTRACT FROM AUTHOR]

Cognitive flexibility, the capacity to adapt behaviour to changes in the environment, is impaired in a range of brain disorders, including schizophrenia and Parkinson's disease. Putative neural substrates of cognitive flexibility include mesencephalic pathways to the ventral striatum (VS) and dorsomedial striatum (DMS), hypothesized to encode learning signals needed to maximize rewarded outcomes during decision‐making. However, it is unclear whether mesencephalic projections to the ventral and dorsal striatum are distinct in their contribution to flexible reward‐related learning. Here, rats acquired a two‐choice spatial probabilistic reversal learning (PRL) task, reinforced on an 80%|20% basis (correct|incorrect responses) that assessed the flexibility of behaviour to repeated reversals of response‐outcome contingencies. We report that optogenetic stimulation of projections from the ventral tegmental area (VTA) to the nucleus accumbens shell (NAcS) in the VS significantly impaired reversal learning when optical stimulation was temporally aligned with negative feedback (i.e., reward omission). VTA → NAcS stimulation during other phases of the behavioural task was without significant effect. Optogenetic stimulation of projection neurons from the substantia nigra (SN) to the DMS, aligned either with reward receipt or omission or prior to making a choice, had no significant effect on reversal learning. These findings are consistent with the notion that increased activity in the VTA → NAcS pathway disrupts behavioural flexibility by impairing learning from negative reinforcement. [ABSTRACT FROM AUTHOR]

Mathematics, along with reading and writing, is a core academic subject in the school curriculum. The development of mathematical skills is influenced by various cognitive factors, with executive functions (EF) playing a central role. EF, which encompasses working memory, inhibitory control, and cognitive flexibility, is critical for supporting complex cognitive processes required for problem-solving and mathematical reasoning. Research consistently shows that children with stronger EF tend to achieve better academic outcomes, including in mathematics. The goal of the present study was to examine the relationships between the global EF and its three core components – working memory, inhibitory control, and cognitive flexibility – and their impact on mathematics achievement. The sample for this study consisted of 180 children, aged 8–11 years (mean age: 9.6, SD: 1.0 year; 83 girls, 97 boys). EF was assessed using the Yellow-Red test, while mathematics achievement was evaluated based on teachers’ evaluations of the child’s mathematics performance. The results indicated a statistically significant effect of global EF and its three components on mathematics achievement. Given the potential malleability of EFs, we conclude with recommendations for strategies to enhance EF development at an early school age. [ABSTRACT FROM AUTHOR]

AbstractMental processes responsible for goal-oriented behavior – executive functioning (EF) – include working memory, flexible thinking, and cognitive control. A reliable and valid assessment of EF can inform appropriate interventions and decisions to drive. We investigated the feasibility and validity of a short, iPad-administered EF screening tool in a non-clinical sample: the Coffs Harbour Executive Functioning Screen (CHEFS). Participants (N = 55) completed the CHEFS alongside a neuropsychological assessment of EF used to assess fitness to drive. Discriminant function analysis (DFA) showed that the CHEFS correctly classified 87% of participants to normative clinical ranges on the Verbal Fluency Test. The results suggest that CHEFS is a novel, easily administered tool for assessing EF in a non-clinical sample. DFA is an appropriate within-tool analysis to support the widespread administration of a screening tool to determine fitness to drive and classify patient referral needs. Further assessment is required to determine CHEFS reliability and validity with a broader range of participants varying in neuropsychological functioning, age, ethnicity, test experience, and compared to on-road driving performance. [ABSTRACT FROM AUTHOR]

AbstractObjective: This proof-of-concept study aimed to characterize semantic memory profiles in individuals with human immunodeficiency virus (HIV) and mild neurocognitive impairment. Method: Using a semantic relatedness task, we explored conceptual association and word selection patterns in people living with HIV (PLWH; n = 50) relative to people living without HIV (n = 46). We also studied whether word selection patterns in the PLWH group were associated with working memory capacity, cognitive flexibility and inhibitory control. Results: While accuracy did not differ between groups, PLWH produced significantly longer responses than controls (r = .32), with fewer hypernyms (d = .47), more troponyms (r = .37), and words that were more frequent (r = .39) and had more phonological neighbors (r = .22). These patterns survived covariation with participants’ cognitive status. None of these patterns correlated with measures of working memory, cognitive flexibility, inhibitory control or viral load (all correlation coefficients < .36). Conclusions: Together, these results suggest that PLWH might use alternative word finding strategies during semantic memory navigation, irrespective of the severity of other cognitive symptoms. Such findings contribute to the characterization of cognitive deficits in HIV and to the search for novel markers of the condition. [ABSTRACT FROM AUTHOR]

Creative divergent thinking involves the generation of unique ideas by pulling from semantic memory stores and exercising cognitive flexibility to shape these memories into something new. Although cognitive abilities decline with age, semantic memory tends to remain intact. This study aims to utilize that memory to investigate the effectiveness of a brief cognitive training to improve creative divergent thinking. Older adults were trained using a semantic retrieval strategy to improve creativity in the Alternate Uses Task (AUT) and the Divergent Association Task (DAT). Participants were tested on the AUT and DAT across three time points: before the strategy was introduced (T0 and T1) and afterward (T2). Results showed that the strategy enhances idea novelty in the AUT; additionally, participants that initially scored lowest on the AUT showed the greatest increase in AUT performance. This finding suggests that older adults can use a semantic retrieval strategy to enhance creative divergent thinking. [ABSTRACT FROM AUTHOR]

ABSTRACT Background Methods Results Conclusions Clinical high risk (CHR) youth are known to exhibit cognitive deficits at similar levels to their more severally ill counter parts. Cognitive training (CT) programs offer a promising method for early intervention and the prevention of further cognitive decline in this vulnerable population. However, there are few structured CT intervention programs addressing the needs of CHR youth in LMICs of the Middle East.We conducted a study in the Child and Adolescent Psychiatry Department of Razi University Hospital. Patients were assessed by trained raters with the “Comprehensive Assessment of At‐Risk Mental States” to confirm their CHR status. Cognitive Training (CT) was combined with the Neuropsychological Educational Approach to Remediation (CT‐NEAR) as part of a social rehabilitation program. We enrolled 25 CHR patients and examined several domains of cognitive functioning and evaluated daily functioning prior to starting the intervention and after completion.There were 20 patients who completed the study. The CT‐NEAR group (n = 10) completed an average number 28.33 sessions over 12 weeks, which were matched for therapist time with the TAU group (n = 10). We found statistically significant improvements in CT‐NEAR versus TAU in several cognitive domains; such as cognitive flexibility, memory‐short and long‐term, and verbal fluency. Also, CT‐NEAR versus TAU patients improved in global functioning.Our findings indicate that cognitive remediation versus TAU for Tunisian CHR youth is feasible and effective especially in improving cognitive functioning when delivered in a social rehabilitation context (Bridging Group) and extends to global level of functioning. [ABSTRACT FROM AUTHOR]

“Metacontrol” refers to the ability to find the right balance between more persistent and more flexible cognitive control styles, depending on task demands. Recent research on tasks involving response conflict regulation indicates a consistent link between aperiodic EEG activity and task conditions that demand a more or less persistent control style. In this study, we explored whether this connection between metacontrol and aperiodic activity also applies to cognitive flexibility. We examined EEG and behavioral data from two separate samples engaged in a task-switching paradigm, allowing for an internal replication of our findings. Both studies revealed that aperiodic activity significantly decreased during task switching compared to task repetition. Our results support the predictions of metacontrol theory but contradict those of traditional control theories which would have predicted the opposite pattern of results. We propose that aperiodic activity observed in EEG signals serves as a valid indicator of dynamic neuroplasticity in metacontrol, suggesting that truly adaptive metacontrol does not necessarily bias processing towards persistence in response to every control challenge, but chooses between persistence and flexibility biases depending on the nature of the challenge. [ABSTRACT FROM AUTHOR]

Background: Due to the high heterogeneity of schizophrenia, the factors influencing social cognitive impairment are controversial. The purpose of this study was to investigate the social cognitive dysfunction of deficit schizophrenia (DS), and to explore its clinical impact on the clinical characteristics and neurocognitive function assessment results. Methods: This study involved 100 DS patients, 100 non-deficit schizophrenia (NDS) patients, and 100 healthy controls (HC). Social cognitive functions were assessed using the Eye Complex Emotion Discrimination Task (ECEDT), Game of Dice Task (GDT), and Iowa Gambling Task (IGT), while neurocognitive functions were examined using the Clock Drawing Task (CDT), the Verbal Fluency Task (VFT), Digit Span Test (DST), Stroop Color-word Test (SCWT), and Trail Making Test (TMT). We analyzed the differences in cognitive function among the three groups of patients and the correlation between cognitive function assessment results and Positive and Negative Syndrome Scale (PANSS) scores. Results: Comparison of neurocognitive functions among the three groups through CDT, VFT, DST, SCWT, and TMT revealed that in the values of these tests in the DS group differed significantly from those of the NDS and HC groups. However, the DSB of the NDS group was lower and the TMT results were significantly higher than those of the HC group. In the DS group, ECEDT emotion recognition was positively correlated with stroop colors and stroop interference; the score of gender recognition was positively correlated with VFT, DSF, and SCWT, and TMT-B; the total time spent was positively correlated with TMT; The GDT risky option was negatively correlated with VFT, DST, stroop word, and stroop interference; the negative feedback utilization was negatively correlated with PANSS-Negative; TMT was positively correlated with VFT; IGT was positively correlated with CDT, VFT, DST, and SCWT, but it was negatively correlated with PANSS-Negative and TMT, with statistically significant. Conclusion: There are significant social cognitive impairments in the perception of social information, judgment and resolution of social problems in deficit schizophrenia, which are closely related to negative symptoms and multidimensional neurocognitive dysfunction such as attention, learning, memory, brain information processing speed, cognitive flexibility, and functional executive power. [ABSTRACT FROM AUTHOR]

Objective: This study was to investigate the developmental characteristics of executive function (EF) in obese adolescents and the time-course effects of a 14-week exercise intervention combining aerobic exercise and resistance training on EF in this population. Methods: The experimental group of 28 obese junior high school students participated in the exercise intervention combining aerobic exercise and resistance training, while the control group of 24 healthy weight junior high school students engaged in the regular recess exercise. EF, including inhibition, working memory, and cognitive flexibility, was assessed 1 week prior to the exercise intervention and at 12 and 14 weeks post-intervention. Changes in EF sub-functions in both groups at different time points during the exercise intervention were analyzed. Results: The findings revealed that obese junior high school students exhibited lower levels of inhibition (p = 0.003, Cohen's d = 0.848) and cognitive flexibility (p = 0.013, Cohen's d = 0.706) compared to their healthy weight peers. The exercise intervention combining aerobic exercise and resistance training led to significant improvements in EF among obese junior high school students, with inhibition (p < 0.01, Cohen's d = 0.713; p = 0.003, Cohen's d = 0.683) and cognitive flexibility (p = 0.001, Cohen's d = 0.797; p < 0.01, Cohen's d = 0.890) showing significant improvement at 12 and 14 weeks post-intervention, and working memory demonstrating significant improvement at 14 weeks (p = 0.004, Cohen's d = 0.710). No significant differences were observed in EF over time in healthy weight junior high school students. Conclusion: Obese adolescents had impaired EF, as evidenced by low levels of the inhibition and cognitive flexibility compared to healthy weight adolescents. The exercise intervention combining aerobic exercise and resistance training had a positive effect on EF of obese adolescents. The time-course effects of the intervention on improvements in inhibition, working memory, and cognitive flexibility varied with intervention duration in obese adolescents, with significant changes in inhibition and cognitive flexibility observed at 12 weeks and significant changes in working memory at 14 weeks. [ABSTRACT FROM AUTHOR]

Background: Vaccine hesitancy (the reluctance or refusal to vaccinate) poses a significant threat to public health worldwide, with declining vaccination coverage resulting in the resurgence of vaccine-preventable diseases (e.g., measles) in recent years. Despite efforts to combat vaccine hesitancy through information-based campaigns and other interventions, vaccine-hesitant attitudes persist. Given that such interventions likely expose individuals to information that conflicts with their own viewpoints about vaccination, cognitive flexibility – the ability to adapt one's thoughts, attitudes, beliefs, or behavior in response to changing information or environmental demands – may play a role in vaccine hesitancy. Methods: The current study investigated the relationship between cognitive flexibility and attitudes towards vaccination in a sample of New Zealand residents (N = 601). Cognitive flexibility was measured using perseverative responses in the Wisconsin Card-Sorting Task, and vaccination attitudes were measured using an adapted version of the Multidimensional Vaccine Hesitancy Scale (MVHS). Linear regression was used with MVHS scores as the dependent variable and cognitive flexibility and sociodemographic variables (age, gender, ethnicity, education level, religion) as predictors. Results: Cognitive flexibility predicted personal barriers to vaccination (e.g.," vaccines go against my personal beliefs"), with participants with lower levels of cognitive flexibility reporting greater personal barriers. In contrast, there was no significant relationship between cognitive flexibility and external barriers to vaccination (e.g., "vaccines cost too much"). Additionally, religious participants reported overall higher levels of vaccine hesitancy than non-religious participants. Conclusions: These findings join others demonstrating that individual differences in cognitive style are associated with attitudes towards vaccination, and tentatively suggest that interventions aiming to reduce vaccine hesitancy may be more effective if combined with techniques to increase cognitive flexibility. To be sure, future work is needed to test the causal relationship between cognitive flexibility and attitudes towards vaccination. [ABSTRACT FROM AUTHOR]

Early experience in infancy affects cognitive development. Birds, like mammals, acquire cognitive flexibility attributed to a well-developed telencephalon. Precocial chicks acquire imprintability just after hatching when thyroid hormone (T3) flows into the brain and primes later learning. Here, we show that the perihatch synthesis of T3 paralleling thyroid development is crucial for imprinting and endows newborn chicks with cognitive flexibility via a mechanism involving the nidopallium dorsocaudale, the avian "prefrontal cortex." Imprinted chicks showed higher cognitive flexibility than those unimprinted in switching or reversal task experiments. Notably, we discovered that exogenous T3 endowed similar flexibility in unimprinted chicks. Cognitive stimulation by a surge of thyroid hormone indicates a vertebrate tactic involving high cognitive ability for adapting to environmental changes. [ABSTRACT FROM AUTHOR]

Background: In contrast to most other languages, where the spoken and written words are similar, children that have mastered Spoken Arabic (SA) learn to read a new written form of Arabic usually called Literary Arabic (LA). This phenomenon is called "diglossia". Methods: Based on a series of studies comparing monolingual Arabic speaking and bilingual children, it has been suggested that Arabic speaking individuals develop metacognitive abilities that are considered bilinguals de facto. Some of the cognitive functions that would seem to benefit from fluency in more than one language are metalinguistic and metacognitive awareness. Results: This review article summarizes the results of studies on the relationship between bilingualism, diglossia and executive functions (EFs) which involve metacognitive awareness, selective attention, control of inhibition and cognitive flexibility as well as working memory (phonemic manipulation and metalingual performances). Conclusions: The findings are in line with research results that have shown that bilingualism has a positive effect on the functioning of an individual's attentional system across the lifespan. The neural basis of diglossia in Arabic, as well as the conclusions and implications drawn from the impact of diglossia on EF and on reading in Arabic, are discussed. [ABSTRACT FROM AUTHOR]

Students with reading disabilities form a heterogeneous group: some struggle with accurate and fast reading (dysfluent readers), others with comprehension (poor comprehenders), and some face challenges in both areas (poor readers). Research has indicated a link between executive functioning skills and reading performance; yet, further studies are necessary to fully understand the executive profiles in various types of reading disabilities. The goal of this study was to examine differences in executive functioning among three types of reading disabilities, comparing their performance with that of children without difficulties in either skill (typical readers). Ninety-one students from schools in Portugal participated in the study. The results reveal specific deficits in naming speed and cognitive flexibility in poor readers and dysfluent readers compared to the other groups. Additionally, poor readers exhibited significantly slower processing speed and lower working memory. However, no significant differences were observed in planning. Discriminant function analysis results indicated that the examined executive functions are better at discriminating groups with fluency deficits than those with comprehension difficulties. In conclusion, these results suggest distinct deficit patterns in executive functioning skills across different types of reading disabilities. Taking into account these findings is crucial for effective assessment and intervention with these children. [ABSTRACT FROM AUTHOR]

The aim of the study is to investigate the association of cardiorespiratory fitness (CRF) and muscular strength indicators with gray matter volume (GMV) and to study whether fitness‐related regions of GMV are associated to executive function (EF) in cognitively normal older adults. Ninety‐one cognitively normal older adults (71.69 ± 3.91 years; 57.14% females) participated in this study from the AGUEDA trial. CRF was measured by a 2‐km walking test and a 6‐min walking test. Muscular strength was measured by handgrip, biceps curl, squats, and isokinetic strength tests. T1‐weigthed images were obtained through a magnetic resonance scan. GMV was determined by voxel‐based morphometric analysis. Standardized EF tests were performed. CRF did not show any positive association with GMV. Handgrip strength was positively associated with GMV (p < 0.001) in nine regions (β from 0.6 to 0.8 and k from 106 to 1927) and knee extension strength in three regions (β from 0.4 to 0.5 and k from 76 to 2776). Squats strength was negatively associated with GMV (p < 0.001) in two regions (β = −0.3, k = 1102 and k = 152) and the 2‐km walking test in one region (β = −0.4, k = 99). Only handgrip strength‐related GMV was associated with cognitive flexibility (p = 0.039, β = 0.215) and spatial working memory (p < 0.03, β 0.247–0.317), but not with EF score (p > 0.05). Muscular strength, but no CRF, may be positively related to GMV in cortical and subcortical regions, with implications for specific cognitive domains rather than the overall EF score. Specifically, handgrip strength was the indicator most associated with higher GMV, while squats strength and CRF were negatively related to GMV. ClinicalTrials.gov identifier: NCT05186090. [ABSTRACT FROM AUTHOR]

Cognitive stability, the ability to focus on a current task, and cognitive flexibility, the ability to switch between different tasks, are traditionally conceptualized as opposing end-points on a one-dimensional continuum. This assumption obligates a stability-flexibility trade-off – greater stability equates to less flexibility, and vice versa. In contrast, a recent cued task-switching study suggested that stability and flexibility can be regulated independently, evoking a two-dimensional perspective where trade-offs are optional (Geddert & Egner, Journal of Experimental Psychology: General, 151, 3009–3027, 2022). This raises the question of under what circumstances trade-offs occur. We here tested the hypothesis that trade-offs are guided by cost-of-control considerations whereby stability and flexibility trade off in contexts that selectively promote stability or flexibility, but not when neither or both are promoted. This proposal was probed by analyzing whether a trial-level metric of a stability-flexibility trade-off, an interaction between task-rule congruency and task sequence, varied as a function of a broader block-level context that independently varied demands on stability or flexibility by manipulating the proportion of incongruent and switch trials, respectively. In Experiment 1, we reanalyzed data from Geddert and Egner, Journal of Experimental Psychology: General, 151, 3009–3027, (2022); Experiment 2 was a conceptual replication with a design tweak that controlled for potential confounds due to local trial history effects. The experiments produced robust evidence for independent stability and flexibility adaptation, and for a context-dependent expression of trial-level stability-flexibility trade-offs that generally conformed to the cost-of-control predictions. The current study thus documents that stability-flexibility trade-offs are not obligatory but arise in contexts where either stability or flexibility are selectively encouraged. [ABSTRACT FROM AUTHOR]

Cognitive flexibility, the ability to switch between mental processes to generate appropriate behavioral responses, is reduced with typical aging. Previous studies have found that age‐related declines in cognitive flexibility are often accompanied by variations in the activation of multiple regions. However, no meta‐analyses have examined the relationship between cognitive flexibility in aging and age‐related variations in activation within large‐scale networks. Here, we conducted a meta‐analysis employing multilevel kernel density analysis to identify regions with different activity patterns between age groups, and determined how these regions fall into functional networks. We also employed lateralization analysis to explore the spatial distribution of regions exhibiting group differences in activation. The permutation tests based on Monte Carlo simulation were used to determine the significance of the activation and lateralization results. The results showed that cognitive flexibility in aging was associated with both decreased and increased activation in several functional networks. Compared to young adults, older adults exhibited increased activation in the default mode, dorsal attention, ventral attention, and somatomotor networks, while displayed decreased activation in the visual network. Moreover, we found a global‐level left lateralization for regions with decreased activation, but no lateralization for regions with higher activation in older adults. At the network level, the regions with decreased activation were left‐lateralized, while the regions with increased activation showed varying lateralization patterns within different networks. To sum up, we found that networks that support various mental functions contribute to age‐related variations in cognitive flexibility. Additionally, the aging brain exhibited network‐dependent activation and lateralization patterns in response to tasks involving cognitive flexibility. We highlighted that the comprehensive meta‐analysis in this study offered new insights into understanding cognitive flexibility in aging from a network perspective. [ABSTRACT FROM AUTHOR]

Increasing evidence points out that Executive Functions (i.e., EFs) may be core mechanisms for the generation of resilient responses to adversity. A systematic review testing the relations between either affective (hot) and/or non‐affective (cold) EFs (i.e., inhibition, flexibility and working memory updating) and resilience was conducted. A total of 449 articles were initially identified. After two steps of title‐and‐abstract (k = 449), and full‐text reading filtering (k = 67), 11 studies were reviewed. Three studies included cold measures of working memory and supported significant positive relations between higher working memory functioning and higher trait resilience levels. One study included cold measures of inhibition and another one both hot and cold measures, with only the first one supporting a positive relation between more efficient inhibition and higher trait resilience levels. Finally, 7 studies measured flexibility in its cold and/or hot dimensions and overall supported significant relations between higher flexibility and higher levels of trait, process and outcome resilience measures. These results support the role of EFs performance to promote different forms of resilience. This review allows to identify different issues that need to be addressed in future research and highlight the need to integrate the analysis of all hot and cold EFs components to understand their role in the generation of resilience. [ABSTRACT FROM AUTHOR]

Purpose Family physicians have a higher incidence of burnout, dissatisfaction, and disengagement compared to other medical specialties. Addressing burnout on the individual and systemic level is important to promoting wellness and preventing deleterious effects on physicians and patients. We used the Physician Wellness Inventory (PWI) to assess the effects of a wellness programme designed to equip family physicians with skills to address burnout. Methods The PWI is a fourteen-item 5-point Likert scale broken down into 3 scores; (i) career purpose, (ii) cognitive flexibility, and (iii) distress. The PWI was distributed to a cohort of n  = 111 family physician scholars at 3 time points: January 2021, May–June 2021, and October 2021. The response rate was 96.4% at baseline, and 72.1% overall. Demographic information was collected to assess differences. The survey was distributed online through Qualtrics (Provo, UT). Results Cognitive Flexibility scores at the endpoint were higher for POC scholars than white scholars (P = 0.024). Distress scores for all groups decreased over time. Female scholars were more nervous, and anxious at the start than male scholars (P = 0.012), which decreased over time (P = 0.022). New career scholars were more likely than later career scholars to be distressed (P = 0.007), but both groups' distress decreased over time (P = 0.003). Later career scholars' feelings of being bothered by little interest or pleasure in doing things decreased more than new career scholars (endpoint: P  = 0.022; overall: P  = 0.023). Conclusions The wellness programme shows improvement in PWI scores, indicating the programme content should be evaluated further for system level improvements. [ABSTRACT FROM AUTHOR]

Similarity between tasks is an understudied factor in research on cognitive flexibility. This behavioural experiment had 31 participants perform a task switch paradigm in which participants were required to switch between 4 tasks of varying similarity. The experiment was constructed in a way that simultaneously allows for investigating the impact of mental fatigue and task-rule congruency on the participants. The results indicate that similarity between tasks substantially impacts performance with different effects on RT and accuracy. While learning effects may have negated the impact of mental fatigue across the 5 experimental blocks, a significant decrease in performance was observed within blocks. Furthermore, the exploratory analysis proposes a novel interaction between task-rule incongruent trials and the task of the previous trial. These results support the notion that neither the interference view of cognitive flexibility nor the reconfiguration view are fully adequate at explaining task switch costs if similarity is added as a factor. The presented study presents strong evidence that fundamental findings in the domain of cognitive flexibility may not map linearly to more ecological settings where tasks are often more dissimilar. [ABSTRACT FROM AUTHOR]

Introduction: At the beginning of the COVID-19 pandemic, student placements in the Master of Music Therapy at the University of Melbourne were rapidly redesigned to create alternative online opportunities. Two online placement models; a simulated practicum (or SimPrac) and telehealth placement; were arranged. With little previous literature to draw upon, data was gathered to explore student and supervisor experiences of online placements and develop understanding of pedagogical considerations to inform future planning. Methods: Quantitative data were collected via an adapted Satisfaction with Simulation Experience Scale (SSES) and qualitative data via open-ended survey questions and semi-structured focus group interviews. Results: SSES results indicated high satisfaction from all cohorts with the online placement experience. Qualitative analysis led to the development of four pedagogical considerations for supporting student learning: Respond to Context with Creativity and Flexibility; Scaffold Student Learning; Foster Peer Relationships; and Supplement Online Learning. Discussion: Findings aligned with recent scholarship in the wider field of Work Integrated Learning (WIL) and indicate a need for questioning prevailing modes of music therapy placement delivery in line with the contemporary context. While online placements were not always understood to provide authentic music therapy experiences, this perspective may need further contemplation given the ongoing need for online music therapy service provision. [ABSTRACT FROM AUTHOR]

Cognitive flexibility is a personality trait, which can influence how effectively a healthcare professional can manage a challenging clinical situation. This study explored the cognitive flexibility of undergraduate dental hygiene students at two universities in Asia to gather baseline information in order to consider whether there was an educational need for pre-clinical students with regards to this personality factor. Participants were all undergraduate dental hygiene students in the 2022 academic year at Tokyo Medical and Dental University (TMDU; n = 79) and Taipei Medical University (TMU; n = 88). An anonymous questionnaire was distributed, which included questions on demographic information and the Cognitive Flexibility Inventory (CFI). The response rates were 97.5% (TMDU) and 89.8% (TMU). The CFI total scores were 91.77 for TMDU and 95.87 for TMU, and there was no significant difference between the two schools. The Alternatives scores were significantly higher in TMU than TMDU (P = 0.044), but there were no significant differences in the Control scores between the two schools. There were also no significant differences between school years of both universities. The dental hygiene students from both dental schools exhibit moderate cognitive flexibility. The educators in both dental schools may consider whether they should investigate and develop this personality factor further during the undergraduate training of their dental hygiene students. [ABSTRACT FROM AUTHOR]

Objective: The present study aimed to determine the effectiveness of Imago therapy on cognitive flexibility and post-traumatic growth in women affected by extramarital affairs. Methods: The research community included all women affected by extramarital affairs in the city of Isfahan (including the Nik Ovin Psychological Clinic and the Hazrat Abolfazl Charity Institute) in the spring of 2024. Accordingly, a group of women affected by extramarital affairs was randomly divided into two groups: an experimental group (15 individuals) and a control group (15 individuals). The experimental group received Imago therapy sessions, while the control group received no treatment. The data were analyzed using repeated measures tests with SPSS software version 23. Findings: The findings indicated that Imago therapy was effective in enhancing psychological flexibility and its subscales, as well as post-traumatic growth and its subscales, in women affected by extramarital affairs (P < 0.05). Conclusion: The obtained results showed that Imago therapy could be utilized as an effective approach for improving women affected by extramarital affairs, playing a significant role in enhancing their quality of life. [ABSTRACT FROM AUTHOR]

This paper introduces a new scale, the Consumers' Cognitive Flexibility Scale (CCF‐Scale). Consumers' Cognitive Flexibility (CCF) is conceptualized as the adaptation to changes in the environment and to product options by exhibiting flexible thoughts, feelings, and actions. This scale is a new measure of consumers' mental capabilities to understand and evaluate unknown products. Especially, really new products (RNPs) are highly innovative and different from well‐known products in the market. A flexible mindset can help integrate RNPs into existing knowledge structures. The CCF‐Scale was developed and tested with four prestudies and four representative studies with 1057, 696, 494 German, and 506 US consumers. The prestudies were used to ensure face and content validity and to select products for criterion validity. The findings demonstrate a reliable and valid scale in both countries consisting of 14 items with three CCF‐facets: Coping (with consumption problems), Perspective (change for product/information evaluation), and Alignment (to changes in the environment). Results show that the CCF‐facets help explain RNP‐acceptance across different categories (e.g., food, furniture, and digital services). One limitation is the article's focus on RNPs. Still, marketers can use these findings to adjust instructions on how to use RNPs and to communicate more effectively, for example by using analogies. [ABSTRACT FROM AUTHOR]

Executive function is important to the success of an individual. Children who have a history of being abused mentally and physically before entering a residential care home may have executive function deficits. They often face fear, stress, and a lack of interpersonal interaction, which affects their executive function. This quasi-experimental study aimed to increase children's executive function through the I AM TAP Program. This program integrates sensory and physical activities, including working memory, inhibitory control, and cognitive flexibility. Two residential care homes of young children aged 3-5 years in the Bangkok Metropolitan Region were randomly assigned to experimental and control groups. Then, 36 children from each setting and 11 caregivers were selected according to the inclusion criteria. The experimental group received I AM TAP Program training twice weekly for 9 weeks, 20-30 minutes each session. The control group attended the routine activities provided in a residential care home. Executive function was assessed with the Mahidol University Executive Function-101 instrument. The data were analyzed using independent t-tests, paired t-tests, and covariance analysis. The results of this study, a testament to the effectiveness of the I AM TAP Program, revealed a significant increase in the mean scores of executive functions on 3 subscales in the experimental group. These scores not only improved from the pre-program levels but also surpassed those of the control group, as measured one week after program completion. This promising outcome suggests that the I AM TAP Program has the potential to enhance executive function in young children. Nurses can potentially apply this program to promote executive function, and caregivers can be equipped with information on how to support the children in the residential care home. However, it is crucial to conduct further testing with various groups of children in different settings before considering widespread implementation. [ABSTRACT FROM AUTHOR]

This study examined the impact of sport-specific cognitive training (CT) on executive functions (EFs) in youth soccer players. Thirty-one athletes (13–15 years) participated, 13 in the intervention group (IG) and 18 in the control group (CG). The IG underwent an 8-week soccer-focused CT program, while the CG maintained regular training. The assessments included working memory, inhibition, and cognitive flexibility tasks. The results revealed no significant improvements in EFs in the IG compared to those in the CG. Both groups showed enhanced cognitive flexibility, possibly due to general cognitive development or learning effects. The study suggested that an 8-week sport-specific CT may not enhance EFs in young soccer players, potentially due to a ceiling effect in highly skilled athletes. These findings should be considered when designing cognitive training programs for athletes, and future research could explore the optimal duration of such programs. [ABSTRACT FROM AUTHOR]

Objective: The study aims to examine family functionality, emotion regulation difficulties, preference for loneliness, social exclusion, internalizing and externalizing disorders, and executive functions in children with Attention Deficit Hyperactivity Disorder (ADHD) and Cognitive Disengagement Syndrome (CDS) and compare with ADHD, and ADHD+ Oppositional Defiant Disorder (ODD). Method: This study included 842 children aged 8–12 years. The subjects were categorized according to DSM-V as ADHD (n = 246), ADHD + ODD (n = 212), ADHD + CDS (n = 176), and Control group (n = 207). The solitude and social exclusion, difficulties in emotion dysregulation and Barkley SCT scales, Child Behavior Checklist, family assessment device, and Central Vital Signs (CNSVS) test were used. Results: According to the study, children with ADHD + CDS had higher rates of internalizing disorders. They also preferred being alone and experienced more difficulty communicating with their parents and solving problems within the family. Additionally, these children had difficulty recognizing and understanding the emotional reactions of others. The ADHD + ODD group presented a poorer performance on CNSVS domain tests except for the psychomotor speed test than other groups. Also, ADHD + CDS children had the lowest psychomotor speed scores and lower scores on reaction time and cognitive flexibility than pure ADHD children. Conclusion: This study will contribute to the etiology, treatment, and clinical discrimination of ADHD + CDS. [ABSTRACT FROM AUTHOR]

The present study examined whether and how early cognitive flexibility, metalinguistic awareness, including phonological awareness (PA) and morphological awareness (MA), Chinese word reading (CWR), and listening comprehension (LC) influenced Chinese children's later reading comprehension. In total, 153 Chinese children were recruited. Path analysis showed that cognitive flexibility measured when the children were in Grade 1 (Mage = 85.92 months, SD = 4.36) significantly explained the variance of later reading comprehension at Grade 3 (Mage = 103.03 months, SD = 3.80) and all concurrent domain-specific precursors of reading comprehension, except LC. Multiple mediation analyses further demonstrated that MA and CWR partially mediated the effect of cognitive flexibility on reading comprehension. Also, the effect of cognitive flexibility on reading comprehension was mediated partially by two two-mediator paths, PA-LC and MA-CWR. These findings demonstrated that cognitive flexibility could be related to reading comprehension directly and indirectly through multiple pathways involving metalinguistic awareness, word reading, and language comprehension. These findings particularly highlighted the roles of MA and word reading in the association between Chinese readers' cognitive flexibility and their reading comprehension. [ABSTRACT FROM AUTHOR]

Why do followers' reactions to perceived paradoxical leader behavior (PLB) differ? To answer this question, we draw from self-regulation theory and argue that making sense of a paradoxical leader's seemingly contradictory behavior can pose a challenge for followers and requires specific cognitive traits and abilities that enable them to navigate such complex and dynamic environments. We propose that followers who lack these cognitive traits and related abilities find it more difficult to make sense of and navigate their paradoxical leader's behavior, thereby perceiving them as behaviorally unpredictable. This, in turn, impairs followers' self-regulation when working with such leaders, and leads to lower well-being. Conversely, followers endowed with appropriate cognitive traits can make sense of PLB and thrive in these environments. To test our propositions, we conducted two multi-wave field studies. In Study 1, we examine the role of followers' trait cognitive flexibility in interpreting PLB; whereas Study 2 explores the role of followers' trait self-regulation. The findings from these studies support our hypotheses, with an important implication: the efficacy of PLB may not only solely depend on a leader's ability to enact these behaviors but also on their followers' ability to interpret and make sense of them. [ABSTRACT FROM AUTHOR]

Background: A large body of research has identified the positive effects of physical activity on children with autism spectrum disorders (ASD). However, the specific benefits of different types of sports on executive functioning in children with ASD remain unclear. The aim of this study was to further analyze the effects of different sports on executive functioning in children with ASD using reticulated meta-analysis and to establish their effectiveness ranking. Methods: This study conducted a comprehensive online search in Web of Science, PubMed, Cochrane, Embase, and CNKI databases. It included randomized controlled trials and quasi-experimental studies, and synthesized the data using a Bayesian framework. Results: Several relevant studies were included. The results showed that physical activity significantly improved all three dimensions of executive functioning (inhibitory control, cognitive flexibility, and working memory) in children with ASD. The improvement in cognitive flexibility and inhibitory control both reached a medium effect size. However, the improvement in inhibitory control was better than that in cognitive flexibility, while the improvement in working memory did not reach the level of a medium effect. Mini Basketball was effective in improving inhibitory control and cognitive flexibility, but not working memory. Ping Pong was more effective in cognitive flexibility and working memory, but weaker in inhibitory control. Fixed Bicycle was less effective in all three dimensions. Among other interventions, Learning Bicycles, Animal-assisted therapy, and Exergaming performed better in cognitive flexibility. SPARK, Neiyang Gong, and Martial Arts were also effective in improving inhibitory control. However, SPARK and Fixed Bicycle were not significant in improving working memory. Conclusion: Physical activity as an intervention can significantly improve the executive function of children with ASD. The intervention effects of different sports on different dimensions of executive function vary. Mini Basketball was outstanding in improving inhibitory control and cognitive flexibility. Ping Pong was effective in improving cognitive flexibility and working memory. Fixed Bicycle was not effective in any dimension. [ABSTRACT FROM AUTHOR]

Neurorehabilitation in military populations is complicated by higher rates of PTSD and unique characteristics of military institutions. These factors can adversely impact the patient-therapist therapeutic alliance and engagement with the rehabilitation process leading to poorer outcomes. MDMA is a non-classical psychedelic with pro-social and fear regulating properties. MDMA-assisted therapy is being explored as a novel treatment for PTSD that potentially offers rapid symptom improvement and enhances therapeutic alliance.A review of MDMA-assisted therapy for PTSD is provided in the context of neurorehabilitation in military populations. The molecular mechanism of MDMA is outlined and a novel application of MDMA for neurorehabilitation is proposed.This is an expert review and synthesis of the literature.Results from late-stage clinical trials suggest MDMA-assisted therapy for PTSD would be of particular benefit for military populations with PTSD. The unique pro-social properties of MDMA could be leveraged to enhance the therapeutic alliance and patient engagement during neurorehabilitation.The unique qualities and benefits of MDMA and MDMA-assisted therapy for PTSD suggest relevant application in military personnel undergoing neurorehabilitation. There are many similarities in patient-therapist dynamics in PTSD treatment and neurorehabilitation. The properties of MDMA which enhance therapeutic alliance, downregulate fear, and increase cognitive flexibility would potentially benefit both military personnel with and without PTSD undergoing neurorehabilitation. [ABSTRACT FROM AUTHOR]

Galactic cosmic radiation (GCR) is an unavoidable risk to astronauts that may affect mission success. Male rodents exposed to 33‐beam‐GCR (33‐GCR) show short‐term cognitive deficits but reports on female rodents and long‐term assessment are lacking. We asked: What are the longitudinal behavioral effects of 33‐GCR on female mice? Also, can an antioxidant/anti‐inflammatory compound (CDDO‐EA) mitigate the impact of 33‐GCR? Mature (6‐month‐old) C57BL/6J female mice received CDDO‐EA (400 μg/g of food) or a control diet (vehicle, Veh) for 5 days and Sham‐irradiation (IRR) or whole‐body 33‐GCR (0.75Gy) on the 4th day. Three‐months post‐IRR, mice underwent two touchscreen‐platform tests: (1) location discrimination reversal (tests behavior pattern separation and cognitive flexibility, abilities reliant on the dentate gyrus) and (2) stimulus–response learning/extinction. Mice then underwent arena‐based behavior tests (e.g. open field, 3‐chamber social interaction). At the experiment's end (14.25‐month post‐IRR), an index relevant to neurogenesis was quantified (doublecortin‐immunoreactive [DCX+] dentate gyrus immature neurons). Female mice exposed to Veh/Sham vs. Veh/33‐GCR had similar pattern separation (% correct to 1st reversal). There were two effects of diet: CDDO‐EA/Sham and CDDO‐EA/33‐GCR mice had better pattern separation vs. their respective control groups (Veh/Sham, Veh/33‐GCR), and CDDO‐EA/33‐GCR mice had better cognitive flexibility (reversal number) vs. Veh/33‐GCR mice. One radiation effect/CDDO‐EA countereffect also emerged: Veh/33‐GCR mice had slower stimulus–response learning (days to completion) vs. all other groups, including CDDO‐EA/33‐GCR mice. In general, all mice showed normal anxiety‐like behavior, exploration, and habituation to novel environments. There was also a change relevant to neurogenesis: Veh/33‐GCR mice had fewer DCX+ dentate gyrus immature neurons vs. Veh/Sham mice. Our study implies space radiation is a risk to a female crew's longitudinal mission‐relevant cognitive processes and CDDO‐EA is a potential dietary countermeasure for space‐radiation CNS risks. [ABSTRACT FROM AUTHOR]

In the context of the legacy of deficit‐focused research and application of theoretical models in research on minoritized groups that are underrepresented in the literature, we explored the strengths‐based literature among lesbian, gay, bisexual, transgender, and queer (LGBTQ+) people of color to develop a more inclusive and relevant understanding of how posttraumatic growth (PTG) occurs in this population. Our intersectional PTG model is tailored to the experiences of LGBTQ+ people of color that builds upon previous models of PTG, intersectionality theory, and empirical findings of trauma and PTG among LGBTQ+ people of color. Our intersectional PTG model incorporates the unique intrapersonal, interpersonal, institutional, and cultural factors that are unique to this population and contribute to PTG. We challenge the limited scope of Criterion A traumatic events and emphasize empirical findings that support that LGBTQ+ people of color often experience posttraumatic stress after oppression and discrimination. Our model also recognizes the impact of intersecting risk factors, such as gendered racism, that may occur on various levels. Our model acknowledges that LGBTQ+ people of color have often demonstrated PTG in the face of adversity. Intrapersonal factors such as cognitive flexibility, interpersonal factors such as social support, and institutional and cultural factors such as identity‐related activism are identified as key contributors to resilience. We discuss practice implications, highlighting that clinicians should recognize limitations of traditional trauma frameworks and adopt culturally sensitive approaches when working with LGBTQ+ people of color. Overall, our model provides a foundation for strengths‐based interventions and research, emphasizing resiliency and potential for PTG in this population. [ABSTRACT FROM AUTHOR]

The purpose of this study is to examine whether there are differences in critical thinking dispositions and cognitive flexibility among university students based on gender, grade level, and faculty. Additionally, the study will investigate the relationship between these two concepts and their predictive power. The study was conducted using a relational survey model and included 366 university students selected through maximum diversity sampling. The study involved university students from various faculties and grade levels. Data was collected through a personal information form, cognitive flexibility inventory, and critical thinking disposition scale. The data was analyzed using the SPSS 25 program. The results indicate that university students exhibit relatively high levels of cognitive flexibility and critical thinking tendencies. Above the medium level, there was a significant positive relationship between cognitive flexibility and critical thinking tendency. Cognitive flexibility was found to be a significant predictor of critical thinking dispositions, positively and significantly predicting critical thinking disposition and explaining 40% of it. Individuals with critical thinking tendencies exhibit cognitive flexibility, which is also associated with thinking critically. Therefore, cognitive flexibility and critical thinking are interrelated characteristics. [ABSTRACT FROM AUTHOR]

Objectives Methods Results Conclusions Inflexibility of thought and behaviour is a transdiagnostic feature of many neuropsychiatric disorders and presents several empirical measurement challenges. Here, we developed and validated the Flexibility in Daily Life scale (FIDL); a novel, self‐report questionnaire, which captures expressions of cognitive and behavioural flexibility in daily life and is sensitive to natural shifts in these processes across the adult lifespan.The FIDL was developed using a deductive scale development approach, which aimed to capture common themes within the flexibility literature and across diagnoses (e.g. insistence on sameness, preference for routines). Following multidisciplinary consensus, an initial 37‐item questionnaire was submitted for validation in an online sample of 295 healthy adult participants (19–78 years).Exploratory factor analysis produced a revised 21‐item version comprising five factors, labelled: Repetition, Switching, Predictability/Control, Routine, and Thoughts/Beliefs. Internal consistency reliability was good‐to‐strong for the total FIDL score and moderate‐to‐strong for individual subscales. Convergent validity was established between the FIDL and an existing measure of cognitive flexibility. Critically, the FIDL total score evinced a U‐shaped relationship with age, whereby flexibility was lower at the younger and older tails of the lifespan and greater in middle age. The same U‐shaped trajectory emerged for the Repetition, Routine, and Thoughts/Beliefs factors.Overall, the FIDL is a valid and reliable multidimensional measure of flexibility, which upholds a clearly defined factor structure and good psychometric properties. It promises to be a valuable clinical and research tool to assess the natural fluctuations in flexibility across the lifespan and departures thereof. [ABSTRACT FROM AUTHOR]

Research has found that difficulties in emotion regulation negatively impact mental health, whereas cognitive flexibility may promote stress resilience and positive mental health. Little is known about cognitive flexibility and emotion regulation in people with comorbid eating disorder (ED) and anxiety and stress disorders. A transdiagnostic ED population (N = 227) at an outpatient ED treatment facility completed several self-report instruments that measured cognitive flexibility, emotion regulation difficulties, posttraumatic stress disorder (PTSD) symptoms, and generalized anxiety disorder (GAD) symptoms upon admission. We investigated cognitive flexibility and emotion regulation differences for those with an ED without comorbidity and those with various combinations of comorbidity. In a one-way between-groups ANOVA, we investigated differences in cognitive flexibility for those with GAD, PTSD, neither, and both comorbidities. We found a statistically significant difference between these groups, with mean cognitive flexibility inventory scores being the lowest in the group with both comorbidities. However, when controlling for emotion regulation, a one-way between-groups ANCOVA indicated no significant differences in cognitive flexibility between comorbidity groups F(3, 222) = 1.20, p = .31 Partial η2 = .02. Though self-reported cognitive flexibility levels differ among ED patients with and without comorbidities, it appears that these differences are better explained by emotion regulation. Therefore, addressing emotion regulation early in treatment for all individuals with EDs, regardless of comorbidity, is recommended as a future research focus to enhance treatment outcomes. Further research is needed to understand the impact of treating emotion regulation on ED treatment engagement, dropout, and effectiveness. [ABSTRACT FROM AUTHOR]

This study aims to examine the impact of reverse mentoring on the change adaptation behavior of senior employees working in public sector organizations. Specifically, the purpose of this research is to gain insights into enhancing adaptability and organizational change management strategies in employees by studying the sequential mediation of cognitive flexibility and resilience. This study uses a deductive research approach with employees' positivism philosophy to examine the effect of reverse mentoring on change adaptation. It utilizes a purposive sampling technique and data was collected from the employees working in public sector organizations in Pakistan. We employed a time-lagged data collection method to gather insights from a representative employee pool and Mplus for data analysis. The study shows that all variables examined have significant positive effects on each other. Reverse mentoring, cognitive flexibility, and resilience contribute to improved change adaptation in public sector organizations. [ABSTRACT FROM AUTHOR]

To better understand neural processing during adaptive learning of stimulus‐response‐reward contingencies, we recorded synchrony of neuronal activity in anterior cingulate cortex (ACC) and hippocampal rhythms in male rats acquiring and switching between spatial and visual discrimination tasks in a Y‐maze. ACC population activity as well as single unit activity shifted shortly after task rule changes or just before the rats adopted different task strategies. Hippocampal theta oscillations (associated with memory encoding) modulated an elevated proportion of rule‐change responsive neurons (70%), but other neurons that were correlated with strategy‐change, strategy value and reward‐rate were not. However, hippocampal sharp wave‐ripples modulated significantly higher proportions of rule‐change, strategy‐change and reward‐rate responsive cells during post‐session sleep but not pre‐session sleep. This suggests an underestimated mechanism for hippocampal mismatch and contextual signals to facilitate ACC to detect contingency changes for cognitive flexibility, a function that is attenuated after it is damaged. [ABSTRACT FROM AUTHOR]

Nicotine, an addictive compound found in tobacco, functions as an agonist of nicotinic acetylcholine receptors (nAChRs) in the brain. Interestingly, nicotine has been reported to act as a cognitive enhancer in both human subjects and experimental animals. However, its effects in animal studies have not always been consistent, and sex differences have been identified in the effects of nicotine on several behaviors. Specifically, the role that sex plays in modulating the effects of nicotine on discrimination learning and cognitive flexibility in rodents is still unclear. Here, we evaluated sex‐dependent differences in the effect of daily nicotine intraperitoneal (i.p.) administration at various doses (0.125, 0.25, and 0.5 mg/kg) on visual discrimination (VD) learning and reversal (VDR) learning in mice. In male mice, 0.5 mg/kg nicotine significantly improved performance in the VDR, but not the VD, task, while 0.5 mg/kg nicotine significantly worsened performance in the VD, but not VDR task in female mice. Furthermore, 0.25 mg/kg nicotine significantly worsened performance in the VD and VDR task only in female mice. Next, to investigate the cellular mechanisms that underlie the sex difference in the effects of nicotine on cognition, transcriptomic analyses were performed focusing on the medial prefrontal cortex tissue samples from male and female mice that had received continuous administration of nicotine for 3 or 18 days. As a result of pathway enrichment analysis and protein–protein interaction analysis using gene sets of differentially expressed genes, decreased expression of postsynaptic‐related genes in males and increased expression of innate immunity‐related genes in females were identified as possible molecular mechanisms related to sex differences in the effects of nicotine on cognition in discrimination learning and cognitive flexibility. Our result suggests that nicotine modulates cognitive function in a sex‐dependent manner by alternating the expression of specific gene sets in the medial prefrontal cortex. [ABSTRACT FROM AUTHOR]

The purpose of this study was to examine how individual openness to experience influences humor production and to explore the underlying psychological mechanisms of this relationship, specifically focusing on cognitive flexibility (the cognitive path) and ambiguity tolerance (the motivational path). To comprehensively evaluate individuals' humor production ability, Study 1 employed a subjective self‐report questionnaire on sense of humor, while Study 2 used an objective humor dialogue generation task. The results of Study 1 indicated that openness to experience did not directly impact sense of humor; instead, the relationship between openness to experience and sense of humor was fully mediated by cognitive flexibility. In Study 2, findings showed that openness to experience positively predicted humor production ability, with ambiguity tolerance partially mediating this effect. These results suggest that individuals with higher levels of openness to experience have a greater capacity for generating humorous perspectives. Moreover, the study identified two psychological pathways—cognition and motivation—in the process of generating funny ideas. The specific pathway influenced by the measurement method used for humor production further highlights the importance of both cognitive flexibility and ambiguity tolerance in understanding how openness to experience contributes to humor production. [ABSTRACT FROM AUTHOR]

Background: Exciting left DLPFC activity with high frequency and inhibiting right DLPFC with low frequency repetitive transcranial magnetic stimulation (rTMS) has shown antidepressant effects in major depressive disorder (MDD) and executive functions. However, few studies have directly compared unilateral and bilateral protocols. Methods: Forty-seven individuals with treatment-resistant MDD underwent 10 sessions of rTMS over left DLPFC (20 Hz), bilateral DLPFC (left 20 Hz, right 1 Hz), or sham stimulation. Outcomes were depression (Beck Depression Inventory-II), visual-spatialmemory (Corsi Block Test), response inhibition (Go/No-Go task), and cognitive flexibility (Wisconsin Card Sorting Test) assessed before and after treatment. Results: Both unilateral and bilateral rTMS significantly reduced depression levels versus sham controls based on BDI-II scores. While bilateral stimulation did not improve Corsi Test performance, unilateral protocol enhanced visual-spatial memory. On the Go/No-Go task, accuracy was higher in both active stimulation groups compared to sham, with no response time differences. Neither unilateral nor bilateral rTMS had significant effects on cognitive flexibility per the WCST. Conclusions: Despite comparable antidepressant effects, unilateral stimulation had some cognitive advantages over bilateral rTMS, potentially due to greater left dorsolateral prefrontal cortex excitation. Further research on parameter optimization is warranted. [ABSTRACT FROM AUTHOR]

Perspective taking and cognitive flexibility are important abilities for navigating our everyday lives. In this longitudinal study with 108 children (61 girls, mostly White), we investigated the developmental relation between Level 1 perspective taking at 27 months of age and Level 2 perspective taking at 52 months of age as well as relations to cognitive flexibility at 52 months of age. We found that early perspective taking was significantly related to later, more complex perspective taking abilities as well as to cognitive flexibility. This highlights the importance of early perspective taking abilities for later perspective understanding and flexible cognition. [ABSTRACT FROM AUTHOR]

Summary Sleep‐disordered breathing (SDB) is linked to cognitive dysfunction. Although SDB is common in stroke patients, the impact of SDB and its early treatment on cognitive functioning after stroke remains poorly investigated. Therefore, we explored the association between SDB and post‐stroke cognitive functioning, including the impact of early SDB treatment with adaptive servo‐ventilation (ASV) on cognitive recovery from acute event to 3 months post‐stroke. We used data from two studies, which included ischaemic stroke patients (n = 131) and no‐stroke controls (n = 37) without SDB (apnea–hypopnea index, AHI <5/h) and with SDB (AHI≥20/h). Cognitive functioning was assessed within 7 days and 3 months post‐stroke in stroke patients, or at study inclusion in no‐stroke control group, respectively. Stroke patients with SDB were randomized to ASV treatment (ASV+) or usual care (ASV‐). Linear regression adjusted for main confounders assessed the impact of SDB and its treatment on cognitive recovery. The intention‐to‐treat analysis did not show significant associations of SDB ASV+ (n = 30) versus SDB ASV‐ (n = 29) with cognitive recovery. In an exploratory subanalysis, compliant SDB ASV+ (n = 14) versus SDB ASV‐ showed improvements with ASV in visual memory and cognitive flexibility. Combining the stroke and non‐stroke datasets, SDB (n = 85) versus no‐SDB (n = 83) was associated with deficits in visual memory and response inhibition independently of stroke. SDB ASV‐ versus no‐SDB (n = 51) was associated with less improvement in visual memory. There was no substantial evidence for benefits of intention‐to‐treat ASV on cognitive recovery. Exploratory analysis indicated that compliant ASV treatment could benefit visual memory and cognitive flexibility, whereas untreated SDB could contribute to a poor recovery of visual memory. [ABSTRACT FROM AUTHOR]