439 results on '"Bugliani, Marco"'
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2. Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes
3. Circulating Unmethylated CHTOP and INS DNA Fragments Provide Evidence of Possible Islet Cell Death in Youth with Obesity and Diabetes
4. Conventional and Neo-antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors
5. DPP-4 is expressed in human pancreatic beta cells and its direct inhibition improves beta cell function and survival in type 2 diabetes
6. Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF)
7. Author Correction: Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress
8. Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes
9. Fostering improved human islet research: a European perspective
10. Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets
11. Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose
12. Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells
13. The β-Cell in Human Type 2 Diabetes
14. Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes
15. The Pancreatic β Cells in Human Type 2 Diabetes
16. The β-Cell in Human Type 2 Diabetes
17. Insulin secretory granules labelled with phogrin-fluorescent proteins show alterations in size, mobility and responsiveness to glucose stimulation in living β-cells
18. Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin–proteasome system in pancreatic beta cell dysfunction
19. Ultrastructural alterations of pancreatic beta cells in human diabetes mellitus
20. Mast cells infiltrate pancreatic islets in human type 1 diabetes
21. Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms
22. MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion
23. The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells
24. The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity
25. Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress
26. Class II Phosphoinositide 3-Kinase Regulates Exocytosis of Insulin Granules in Pancreatic β Cells
27. Are we overestimating the loss of beta cells in type 2 diabetes?
28. Lipotoxicity disrupts incretin-regulated human β cell connectivity
29. The β-Cell in Human Type 2 Diabetes
30. Ultrastructural morphometric analysis of insulin secretory granules in human type 2 diabetes
31. DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients
32. ADCY5 Couples Glucose to Insulin Secretion in Human Islets
33. Incretin-Modulated Beta Cell Energetics in Intact Islets of Langerhans
34. RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate
35. Protective effects of Stevia rebaudiana extracts on beta cells in lipotoxic conditions
36. Spatiotemporal Correlation Spectroscopy Reveals a Protective Effect of Peptide-Based GLP-1 Receptor Agonism against Lipotoxicity on Insulin Granule Dynamics in Primary Human β-Cells
37. Pro-inflammatory cytokines induce insulin and glucagon double positive human islet cells that are resistant to apoptosis
38. Direct effects of rosuvastatin on pancreatic human beta cells
39. The Pancreatic β Cells in Human Type 2 Diabetes
40. Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes
41. Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis
42. Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
43. Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels
44. Enhanced Signaling Downstream of Ribonucleic Acid-Activated Protein Kinase-Like Endoplasmic Reticulum Kinase Potentiates Lipotoxic Endoplasmic Reticulum Stress in Human Islets
45. Goals of Treatment for Type 2 Diabetes: β-Cell preservation for glycemic control
46. PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ–Induced Pancreatic β-Cell Apoptosis
47. The Direct Effects of Exendin-4 on Human Non-Diabetic and Type 2 Diabetic Islets: 1558-P
48. Is There a Role for Locally Produced Interleukin-1 in the Deleterious Effects of High Glucose or the Type 2 Diabetes Milieu to Human Pancreatic Islets?
49. Hepatitis C Virus Infection and Human Pancreatic β-Cell Dysfunction
50. Functional and Molecular Defects of Pancreatic Islets in Human Type 2 Diabetes
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