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2. Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice

5. Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design

6. Inhibition of cathepsin K with lysosomotropic macromolecular inhibitors

7. Selective inhibition of the collagenolytic activity of human cathepsin K by altering its S2 subsite specificity

8. Evidence that serpin architecture intrinsically supports papain-like cysteine protease inhibition: engineering alpha(sub)1-antitrypsin to inhibit cathepsin proteases

9. The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases

10. TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells

11. Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage

12. Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates

13. Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization

14. Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis

16. Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization

17. Contribution to activity of histidine-aromatic, amide-aromatic, and aromatic-aromatic interactions in the extended catalytic site of cysteine proteinases

22. Diabetes Perturbs Bone Microarchitecture and Bone Strength through Regulation of Sema3A/IGF-1/β-Catenin in Rats

23. The propeptide of cruzipain--a potent selective inhibitor of the trypanosomal enzymes cruzipain and brucipain, and of the human enzyme cathepsin F

25. Free Cholesterol Accumulation in Macrophage Membranes Activates Toll-Like Receptors and p38 Mitogen-Activated Protein Kinase and Induces Cathepsin K

26. Spontaneous Atherothrombosis and Medial Degradation in Apoe −/− , Npc1 −/− Mice

27. Osteoclastic Bone Degradation and the Role of Different Cysteine Proteinases and Matrix Metalloproteinases: Differences Between Calvaria and Long Bone

29. Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor.

31. Contributors

33. Free Cholesterol Accumulation in Macrophage Membranes Activates Toll-Like Receptors and p38 Mitogen-Activated Protein Kinase and Induces Cathepsin K.

34. Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate.

35. Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis.

36. Spontaneous atherothrombosis and medial degradation in Apoe-/-, Npc1-/- mice.

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