1. Multiphoton Tomography for in Vivo Skin Age Determination.
- Author
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Schindele, Andreas, Breunig, Hans Georg, and König, Karsten
- Abstract
Abstract: Nothing represents our age better than our most outer layer: the skin. But the age of the skin may differ from the person's chronological age due to a complex interplay of external and internal factors. A non‐invasive method to determine the skin age on a microscopic level in vivo is clinical multiphoton tomography which allows for direct non‐invasive imaging of biological tissue with subcellular resolution. By directly detecting signals from the major structural proteins of the skin, elastin and collagen, a skin‐age parameter, the so‐called SAAID, can be derived. This elastin‐collagen‐based skin age is exclusively provided by multiphoton tomography. The parameter allows assessing the dermatological skin status and evaluating the effects of cosmetic products like anti‐ageing creams or physical procedures such as laser treatments on a microscopic scale in vivo. Furthermore, the skin‐age parameter provides information on the influence of UV exposure and other skin‐damaging processes and helps NASA and ESA to understand skin‐ageing effects and wound healing related problems due to extended stays in space. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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