1. Individual and Center-Level Factors Affecting Mortality Among Extremely Low Birth Weight Infants
- Author
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John M. Dagle, Lei Li, Abhik Das, C. Michael Cotten, Edward F. Bell, Dan L. Ellsbury, Nancy S. Newman, Dennis Wallace, P. Brian Smith, Jeffrey C. Murray, Waldemar A. Carlo, Michele C. Walsh, Brandon W. Alleman, Abbot R. Laptook, Namasivayam Ambalavanan, Seetha Shankaran, Rosemary D. Higgins, Ellen C. Hale, Barbara J. Stoll, Matthew M. Laughon, and Ronald N. Goldberg
- Subjects
Male ,Pediatrics ,medicine.medical_specialty ,Selected interventions ,Gestational Age ,Infant, Premature, Diseases ,Hospital mortality ,Article ,Hospitals, University ,Risk Factors ,Cause of Death ,Intensive Care Units, Neonatal ,Humans ,Medicine ,Hospital Mortality ,Registries ,Practice Patterns, Physicians' ,Cause of death ,business.industry ,Mortality rate ,Infant, Newborn ,Gestational age ,Infant newborn ,United States ,Low birth weight ,Infant, Extremely Low Birth Weight ,Pediatrics, Perinatology and Child Health ,Gestation ,Female ,medicine.symptom ,business - Abstract
OBJECTIVE:To examine factors affecting center differences in mortality for extremely low birth weight (ELBW) infants.METHODS:We analyzed data for 5418 ELBW infants born at 16 Neonatal Research Network centers during 2006–2009. The primary outcomes of early mortality (≤12 hours after birth) and in-hospital mortality were assessed by using multilevel hierarchical models. Models were developed to investigate associations of center rates of selected interventions with mortality while adjusting for patient-level risk factors. These analyses were performed for all gestational ages (GAs) and separately for GAs RESULTS:Early and in-hospital mortality rates among centers were 5% to 36% and 11% to 53% for all GAs, 13% to 73% and 28% to 90% for GAs CONCLUSIONS:Center intervention rates explain a portion of the center variation in mortality, especially for infants born at
- Published
- 2013