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Your search keyword '"Boei, J.J.W.A."' showing total 17 results
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17 results on '"Boei, J.J.W.A."'

9. The detection and evaluation of aneugenic chemicals

Author

Parry, James M, primary, Parry, E.M, additional, Boumer, R, additional, Doherty, A, additional, Ellard, S, additional, O'Donovan, J, additional, Hoebee, B, additional, de Stoppelaar, J.M, additional, Mohn, G.R, additional, Önfelt, A, additional, Renglin, A, additional, Schultz, N, additional, Soderpalm-Bemdes, C, additional, Jensen, K.G, additional, Kirsch-Volders, M, additional, Elhajouji, A, additional, Van Hummelen, P, additional, Degrassi, F, additional, Antoccia, A, additional, Cimini, D, additional, Izzo, M, additional, Tanzarella, C, additional, Adler, I.-D, additional, Kliesch, U, additional, Schriever-Schwemmer, G, additional, Gasser, P, additional, Crebelli, R, additional, Carere, A, additional, Andreoli, C, additional, Benigni, R, additional, Leopardi, P, additional, Marcon, F, additional, Zinjo, Z, additional, Natarajan, A.T, additional, Boei, J.J.W.A, additional, Kappas, A, additional, Voutsinas, G, additional, Zarani, F.E, additional, Patrinelli, A, additional, Pachierotti, F, additional, Tiveron, C, additional, and Hess, P, additional

Published
1996
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12. Recent Developments in the Assessment of Chromosomal Damage

Author

Natarajan, A.T., primary, Balajee, A.S., additional, Boei, J.J.W.A., additional, Chatterjee, S., additional, Darroudi, F., additional, Grigorova, M., additional, Noditi, M., additional, Oh, H.J., additional, Slijepcevic, P., additional, and Vermeulen, S., additional

Published
1994
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14. Intrachanges as part of complex chromosome-type exchange aberrations

Author

Boei, J.J.W.A., Vermeulen, S., Moser, J., Mullenders, L.H.F., and Natarajan, A.T.

Abstract

The chromosome-type exchange aberrations induced by ionizing radiation during the G 0 /G 1 phase of the cell cycle are believed to be the result of illegitimate rejoining of chromosome breaks. From numerous studies using chromosome painting, it has emerged that even after a moderate dose of radiation, a substantial fraction of these exchanges is complex. Most of them are derived from the free interaction between the ends of three or more breaks. Other studies have demonstrated that chromosomes occupy distinct territories in the interphase nucleus. Since breaks that are in close proximity have an enhanced interaction probability, it seems likely that after ionizing radiation many of the interacting breaks will be present within one chromosome or chromosome arm. Unfortunately, the majority of these intrachanges remain undetected, even when sophisticated molecular cytogenetic detection methods (i.e. mFISH) are applied to paint all chromosome pairs in distinct colors. In the present paper, we evaluate the limitations of full-color painting for the detection of complex exchanges and the correct interpretations of break interactions.

Published
2002
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15. Discrimination between complete and incomplete chromosome exchanges in X-irradiated human lymphocytes using FISH with pan-centromeric and chromosome specific DNA probes in combination with...

Author

Fomina, J., Darroudi, F., Boei, J. J. W. A., Boei, J.J.W.A., Natarajan, A. T., and Natarajan, A.T.

Subjects
CHROMOSOMES, CENTROMERE, TELOMERIZATION
Abstract

Focuses on the discrimination between radiation-induced complete and incomplete chromosome exchanges using chromosome painting. Detection of centromeres and telomeres in fluorescence in situ hybridization (FISH) assay; Impact of the combined FISH Assay on lymphocytes; Observation of low fraction of true incomplete exchanges in lymphocytes.

Published
2000

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