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Discrimination between complete and incomplete chromosome exchanges in X-irradiated human lymphocytes using FISH with pan-centromeric and chromosome specific DNA probes in combination with...

Authors :
Fomina, J.
Darroudi, F.
Boei, J. J. W. A.
Boei, J.J.W.A.
Natarajan, A. T.
Natarajan, A.T.
Source :
International Journal of Radiation Biology; Jun2000, Vol. 76 Issue 6, 4 Black and White Photographs, 1 Diagram, 3 Charts
Publication Year :
2000

Abstract

Focuses on the discrimination between radiation-induced complete and incomplete chromosome exchanges using chromosome painting. Detection of centromeres and telomeres in fluorescence in situ hybridization (FISH) assay; Impact of the combined FISH Assay on lymphocytes; Observation of low fraction of true incomplete exchanges in lymphocytes.

Details

Language :
English
ISSN :
09553002
Volume :
76
Issue :
6
Database :
Complementary Index
Journal :
International Journal of Radiation Biology
Publication Type :
Academic Journal
Accession number :
3847474