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363 results on '"Blasco, Miquel"'

2. Genetic Characterization of Kidney Failure of Unknown Etiology in Spain: Findings From the GENSEN Study

Author

Eugenia García Montemayor, Victoria, Salgueira Lazo, Mercedes, Mazuecos Blanca, Auxiliadora, Jiménez Salcedo, Tamara, José Espigares Huete, María, Araceli Jiménez Vibora, Elena, Álamo Caballero, Concepción, Banegas Deras, Eduardo J., Alonso Bethencourt, Alejandro, Rodríguez García, Alejandra, Fernández Granados, Saulo, Fernández Fresnedo, Gema, Calle García, Leonardo, Martín García, Jesús, Estifan Kasabji, Jorge, Jesús Izquierdo, María, Mouzo Mirco, Ricardo, García Agudo, Rebeca, de Arriba de la Fuente, Gabriel, Facundo Molas, Carme, Xipell Font, Marc, Yugueros González, Alejandra, Antóns, Paula, Ibernon Vilaro, Meritxell, de la Fuente Fernández, Vanessa, González Galván, Yussel, Cabezas, Antonio, Castro Alonso, Cristina, Juan García, Isabel, Garín Cascales, Eduardo, Sebastiá Morant, Josepa, Luna Complejo, Enrique, María Díaz Campillejo, Rosa, González Sanchidrián, Silvia, Cao Vilariño Complejo, Mercedes, Sierra Carpio, Milagros, Ortega Díaz, Mayra, Sánchez Hernández, Rosa, Ossorio González, Marta, Vega Martínez, Almudena, Teresa López Picasso, María, Goma, Elena, Giorgi, Martín, Martínez Miguel, Patricia, Gutiérrez Martínez, Eduardo, Paraíso Cuevas, Vicente, Echarri, Rocío, Martínez, Víctor, Pérez Arnedo, Mario, Juliana Castañeda Infante, Laura, Antonio Menacho Miguel, Jose, Blasco, Miquel, Quiroga, Borja, García-Aznar, José M., Castro-Alonso, Cristina, Fernández-Granados, Saulo J., Luna, Enrique, Ossorio, Marta, Izquierdo, María Jesús, Sanchez-Ospina, Didier, Castañeda-Infante, Laura, Mouzo, Ricardo, Cao, Mercedes, Besada-Cerecedo, María L., Pan-Lizcano, Ricardo, Torra, Roser, Ortiz, Alberto, and de Sequera, Patricia

Published
2024
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3. The role of complement in kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Alberici, Federico, Antonucci, Luca, Avcin, Tadej, Bagga, Arvind, Bajema, Ingeborg M., Blasco, Miquel, Chauvet, Sophie, Cook, H. Terence, Cravedi, Paolo, Dragon-Durey, Marie-Agnès, Fischer, Lauren, Fogo, Agnes B., Frazer-Abel, Ashley, Frémeaux-Bacchi, Véronique, Görlich, Nina, Haas, Mark, Humphreys, Alister, Jha, Vivekanand, Jauhal, Arenn, Kavanagh, David, Kronbichler, Andreas, Lafayette, Richard A., Lanning, Lynne D., Lemaire, Mathieu, Le Quintrec, Moglie, Licht, Christoph, Liew, Adrian, McAdoo, Steve, Medjeral-Thomas, Nicholas R., Meroni, Pier Luigi, Morelle, Johann, Nester, Carla M., Praga, Manuel, Ramachandran, Raja, Reich, Heather N., Remuzzi, Giuseppe, Rodríguez de Córdoba, Santiago, Robinson, Gary, Ronco, Pierre, Rossing, Peter, Salant, David J., Sethi, Sanjeev, Silkjaer, Marianne, Song, Wen-chao, Spoleti, Fabrizio, Taylor, Ronald P., van de Kar, Nicole C.A.J., van Kooten, Cees, Woodward, Len, Zhang, Yuzhou, Zipfel, Peter F., Zuccato, Marco, Vivarelli, Marina, Barratt, Jonathan, Beck, Laurence H., Jr., Fakhouri, Fadi, Gale, Daniel P., Goicoechea de Jorge, Elena, Mosca, Marta, Noris, Marina, Pickering, Matthew C., Susztak, Katalin, Thurman, Joshua M., Cheung, Michael, King, Jennifer M., Jadoul, Michel, Winkelmayer, Wolfgang C., and Smith, Richard J.H.

Published
2024
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6. Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA

Author

Hemmelder, Marc H, Noordzij, Marlies, Vart, Priya, Hilbrands, Luuk B, Jager, Kitty J, Abrahams, Alferso C, Arroyo, David, Battaglia, Yuri, Ekart, Robert, Mallamaci, Francesca, Malloney, Sharon-Rose, Oliveira, Joao, Rydzewski, Andrzej, Sridharan, Sivakumar, Vogt, Liffert, Duivenvoorden, Raphaël, Gansevoort, Ron T, Franssen, Casper FM, van der Net, Jeroen B, Essig, Marie, du Buf-Vereijken, Peggy WG, van Ginneken, Betty, Maas, Nanda, van Jaarsveld, Brigit C, Bemelman, Frederike J, Klingenberg-Salahova, Farah, Heenan-Vos, Frederiek, Vervloet, Marc G, Nurmohamed, Azam, Abramowicz, Daniel, Verhofstede, Sabine, Maoujoud, Omar, Malfait, Thomas, Fialova, Jana, Melilli, Edoardo, Favà, Alexandre, Cruzado, Josep M, Perez, Nuria Montero, Lips, Joy, Krepel, Harmen, Adilovic, Harun, Hengst, Maaike, Konings, Constantijn JAM, Braconnier, Philippe, Weis, Daniel, Gellert, Ryszard, Alferes, Daniela G, Radulescu, Daniela, Zakharova, Elena V, Ambuehl, Patrice Max, Guidotti, Rebecca, Walker, Andrea, Lepeytre, Fanny, Rabaté, Clémentine, Rostoker, Guy, Marques, Sofia, Azasevac, Tijana, Majstorovic, Gordana Strazmester, Katicic, Dajana, Dam, Marc ten, Krüger, Thilo, Brzosko, Szymon, Liakopoulos, Vassilios, Zanen, Adriaan L, Logtenberg, Susan JJ, Fricke, Lutz, Kuryata, Olexandr, Slebe, Jeroen JP, ElHafeez, Samar Abd, Kemlin, Delphine, van de Wetering, Jacqueline, Reinders, Marlies EJ, Hesselink, Dennis A, van Gestel, J Kal-, Eiselt, Jaromir, Kielberger, Lukas, El-Wakil, Hala S, Verhoeven, Martine AM, Logan, Ian, Canal, Cristina, Facundo, Carme, Ramos, Ana M, Debska-Slizien, Alicja, Veldhuizen, Nicoline MH, Tigka, Eirini, Konsta, Maria Anna Polyzou, Panagoutsos, Stylianos, Postorino, Adele, Cambareri, Francesco, Matceac, Irina, Nistor, Ionut, Covic, Adrian, Groeneveld, JHM, Jousma, Jolanda, van Buren, Marjolijn, Diekmann, Fritz, Oppenheimer, Federico, Blasco, Miquel, Pereira, Tiago Assis, and dos Santos, Augusto Cesar Soares

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Kidney Disease, Patient Safety, Clinical Research, 4.1 Discovery and preclinical testing of markers and technologies, Detection, screening and diagnosis, Good Health and Well Being, Aged, Aged, 80 and over, COVID-19, COVID-19 Testing, Female, Humans, Intensive Care Units, Male, Middle Aged, Outcome Assessment, Health Care, Renal Dialysis, SARS-CoV-2, ERACODA Collaborators, dialysis, functional health status, mental health status, survival, Urology & Nephrology, Clinical sciences
Abstract

BackgroundCoronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis.MethodsWe analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression.ResultsIn 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8-6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome.ConclusionsMortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis.

Published
2022

7. Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.

Author

Ramos, Alex, Youssef, Lina, Molina, Patricia, Torramadé-Moix, Sergi, Martinez-Sanchez, Julia, Moreno-Castaño, Ana Belen, Blasco, Miquel, Guillén-Olmos, Elena, De Moner, Blanca, Pino, Marc, Tortajada, Marta, Camacho, Marta, Borrell, Maria, Crovetto, Francesca, Ramirez-Bajo, Maria Jose, Ventura-Aguiar, Pedro, Banon-Maneus, Elisenda, Rovira, Jordi, Escolar, Gines, and Carreras, Enric

Subjects
EXTRACELLULAR vesicles, PREGNANCY complications, ENDOTHELIUM diseases, PREGNANT women, INFLAMMATION
Abstract

Background: Preeclampsia (PE) is a pregnancy complication characterized by hypertension, proteinuria, endothelial dysfunction, and complement dysregulation. Placenta-derived extracellular vesicles (EVs), necessary in maternal–fetal communication, might contribute to PE pathogenesis. Moreover, neutrophil extracellular traps (NETs) play a pathogenic role in other complement-mediated pathologies, and their contribution in PE remains unexplored. Materials and methods: EVs were isolated from PE (peEVs) and normotensive pregnant women sera. NETs were obtained incubating donor-pre-activated neutrophils with PE or control sera. Microvascular (HMEC) endothelial cells (ECs) were incubated with PE or control sera with or without (depleted sera) EVs or NETs, to assess changes in VCAM-1, ICAM-1, VE-cadherin, eNOS, VWF, ROS, and C5b-9 deposits. Results were expressed as fold increase vs. control. Results: VWF, VCAM-1, and ROS expression was significantly higher in cells exposed to PE sera vs. control (12.3 ± 8.1, 3.6 ± 2.3, and 1.8 ± 0.2, respectively, p < 0.05), though significantly lower in cells exposed to depleted PE (dPE) sera (6.1 ± 2.7, 0.7 ± 0.6, and 1.2 ± 0.1, respectively, vs. control, p < 0.05). EC exposure to depleted control sera supplemented with peEVs (dC+peEVs) significantly increased VWF, VCAM-1, and ROS compared to non-supplemented sera (4.5 ± 0.3, 2.8 ± 2.0, and 1.4 ± 0.2, respectively, p < 0.05). ICAM-1, VE-cadherin, and C5b-9 did not differ among groups. ECs incubated with PE-NETs increased VWF and VCAM-1 and decreased VE-cadherin expression vs. control (4 ± 1.6, 5.9 ± 1.2, and 0.5 ± 0.1, respectively, p < 0.05), and notably increased C5b-9 deposit (7.5 ± 2.9, p < 0.05). ICAM-1 and ROS did not differ. Conclusions: Both circulating EVs and NETs from PE pregnant women exhibit a deleterious effect on ECs. Whereas EVs trigger a pro-oxidant and proinflammatory state, NETs potentiate the activation of the complement system, as already described in PE. [ABSTRACT FROM AUTHOR]

Published
2024
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11. The Role of Complement in Kidney Disease: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Vivarelli, Marina, primary, Barratt, Jonathan, additional, Beck, Laurence H., additional, Fakhouri, Fadi, additional, Gale, Daniel P., additional, de Jorge, Elena Goicoechea, additional, Mosca, Marta, additional, Noris, Marina, additional, Pickering, Matthew C., additional, Susztak, Katalin, additional, Thurman, Joshua M., additional, Cheung, Michael, additional, King, Jennifer M., additional, Jadoul, Michel, additional, Winkelmayer, Wolfgang C., additional, Smith, Richard J.H., additional, Alberici, Federico, additional, Antonucci, Luca, additional, Avcin, Tadej, additional, Bagga, Arvind, additional, Bajema, Ingeborg M., additional, Blasco, Miquel, additional, Chauvet, Sophie, additional, Cook, H. Terence, additional, Cravedi, Paolo, additional, Dragon-Durey, Marie-Agnès, additional, Fischer, Lauren, additional, Fogo, Agnes B., additional, Frazer-Abel, Ashley, additional, Frémeaux-Bacchi, Véronique, additional, Görlich, Nina, additional, Haas, Mark, additional, Humphreys, Alister, additional, Jha, Vivekanand, additional, Jauhal, Arenn, additional, Kavanagh, David, additional, Kronbichler, Andreas, additional, Lafayette, Richard A., additional, Lanning, Lynne D., additional, Lemaire, Mathieu, additional, Le Quintrec, Moglie, additional, Licht, Christoph, additional, Liew, Adrian, additional, McAdoo, Steve, additional, Medjeral-Thomas, Nicholas R., additional, Meroni, Pier Luigi, additional, Morelle, Johann, additional, Nester, Carla M., additional, Praga, Manuel, additional, Ramachandran, Raja, additional, Reich, Heather N., additional, Remuzzi, Giuseppe, additional, Rodríguez de Córdoba, Santiago, additional, Robinson, Gary, additional, Ronco, Pierre, additional, Rossing, Peter, additional, Salant, David J., additional, Sethi, Sanjeev, additional, Silkjaer, Marianne, additional, Song, Wen-chao, additional, Spoleti, Fabrizio, additional, Taylor, Ronald P., additional, van de Kar, Nicole C.A. J., additional, van Kooten, Cees, additional, Woodward, Len, additional, Zhang, Yuzhou, additional, Zipfel, Peter F., additional, and Zuccato, Marco, additional

Published
2024
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13. The STARMEN trial indicates that alternating treatment with corticosteroids and cyclophosphamide is superior to sequential treatment with tacrolimus and rituximab in primary membranous nephropathy

Author

Praga, Manuel, Sevillano, Angel, Caravaca-Fontan, Fernando, Trujillo, Hernando, Gutiérrez, Eduardo, Juarez, Gema Fernandez, Shabaka, Amir, Rojas-Rivera, Jorge, Egido, Jesus, Ortiz, Alberto, Goicoechea, Marian, Verdalles, Úrsula, Segarra, Alfons, Agraz, Irene, Martín-Reyes, Guillermo, Perea, Lara, Valera, Ildefonso, Martín, Mónica, Cabello, Virginia, Pérez Valdivia, Miguel Angel, Quintana, Luis F., Blasco, Miquel, Cao, Mercedes, Muñiz, Andrés López, Avila, Ana, Malek, Tamara, Espinosa, Mario, Rabasco, Cristina, Diaz, Montserrat, DaSilva, Iara, Bonet, Jordi, Navarro, Maruja, Gómez-Martino, Juan Ramón, Rivas, Begoña, Rodríguez-Moreno, Antolina, Galeano, Cristina, Romera, Ana, Huerta, Ana, Rodríguez-Paternina, Ezequiel, Vigil, Ana, Alcázar, Roberto, Paraíso, Vicente, Barrio, Vicente, Wetzels, Jack, Logt, Anne-Els van de, Hofstra, Julia, Fernández-Juárez, Gema, Justino, Joana, Caravaca-Fontán, Fernando, Ávila, Ana, Varela, Alfonso, Díez, Montserrat, Diezhandino, Marian Goicoechea, Bonet, Jose, Plaisier, Emmanuelle, Segarra, Alfonso, Lambeau, Gérard, and Ronco, Pierre

Published
2021
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14. Management of thrombotic microangiopathy in pregnancy and postpartum: report from an international working group

Author

Fakhouri, Fadi, Scully, Marie, Provôt, François, Blasco, Miquel, Coppo, Paul, Noris, Marina, Paizis, Kathy, Kavanagh, David, Pène, Frédéric, Quezada, Sol, Hertig, Alexandre, Kissling, Sébastien, O'Brien, Patrick, Delmas, Yahsou, Alberio, Lorenzo, Winer, Norbert, Veyradier, Agnès, Cataland, Spero, Frémeaux-Bacchi, Véronique, Loirat, Chantal, Remuzzi, Giuseppe, and Tsatsaris, Vassilis

Published
2020
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16. Factor B Inhibition with Iptacopan in Recurrent C3 Glomerulopathy Following Kidney Transplant: A Report of Two Cases

Author

Escudero-Saiz, Víctor J., primary, Gonzalez, Ángela, additional, García-Herrera, Adriana, additional, Larque, Ana B., additional, Bomback, Andrew S., additional, Morantes, Laura, additional, Martínez-Chillarón, Marta, additional, Ollé, Júlia, additional, Guillén, Elena, additional, Xipell, Marc, additional, Molina-Andújar, Alicia, additional, Rodríguez, Diana, additional, Cuadrado, Elena, additional, Cacho, Judit, additional, Arana, Carolt, additional, Esforzado, Núria, additional, Bastida, Carla, additional, Poch, Esteban, additional, Diekman, Fritz, additional, Cucchiari, David, additional, Quintana, Luis F., additional, and Blasco, Miquel, additional

Published
2024
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17. Hair cortisol and changes in cortisol dynamics in chronic kidney disease

Author

Boswell, Laura, primary, Vega-Beyhart, Arturo, additional, Blasco, Miquel, additional, Quintana, Luis F., additional, Rodríguez, Gabriela, additional, Díaz-Catalán, Daniela, additional, Vilardell, Carme, additional, Claro, María, additional, Mora, Mireia, additional, Amor, Antonio J., additional, Casals, Gregori, additional, and Hanzu, Felicia A., additional

Published
2024
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19. De cap a peus: avaluació de la competència fraseològica de l'alumnat de secundària

Author

Martines, Josep, Universidad de Alicante. Departamento de Filología Catalana, Gonzàlvez Blasco, Miquel, Martines, Josep, Universidad de Alicante. Departamento de Filología Catalana, and Gonzàlvez Blasco, Miquel

Abstract

La disciplina fraseològica s’ha constituït com un camp d’estudi fructífer al si de les investigacions lingüístiques. En l’actualitat, la fraseologia no es limita a les expressions fixades dels inventaris, sinó que s’amplia i abraça una àmplia gamma de patrons i combinacions lingüístiques recurrents. En el camp de la Didàctica, però, encara són molts els autors que lamenten l’absència de criteris ferms per al tractament dins l’aula. El nostre treball percaça avaluar la competència fraseològica de l’alumnat de secundària a través d’un estudi basat en enquestes. Analitzem el tractament de la fraseologia en els documents normatius del sistema educatiu valencià i exposem les noves aportacions a la Fraseodidàctica, amb propostes de millora.

Published
2024

20. Impact of severe acute kidney injury and chronic kidney disease on allogeneic hematopoietic cell transplant recipients: a retrospective single center analysis

Author

Gutiérrez-García, Gonzalo, Villarreal, Jesús, Garrote, Marta, Rovira, Montserrat, Blasco, Miquel, Suárez-Lledó, María, Rodríguez-Lobato, Luis Gerardo, Charry, Paola, Rosiñol, Laura, Marín, Pedro, Pedraza, Alexandra, Solano, María Teresa, Ramos, Carla, de Llobet, Noemí, Lozano, Miquel, Cid, Joan, Martínez, Carmen, Poch, Esteban, Carreras, Enric, Urbano-Ispizua, Álvaro, Fernández-Avilés, Francesc, Pereira, A., and Quintana, Luis F.

Published
2020
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21. Complement and coagulation cascades activation is the main pathophysiological pathway in early-onset severe preeclampsia revealed by maternal proteomics

Author

Youssef, Lina, Miranda, Jezid, Blasco, Miquel, Paules, Cristina, Crovetto, Francesca, Palomo, Marta, Torramade-Moix, Sergi, García-Calderó, Héctor, Tura-Ceide, Olga, Dantas, Ana Paula, Hernandez-Gea, Virginia, Herrero, Pol, Canela, Nuria, Campistol, Josep Maria, Garcia-Pagan, Joan Carles, Diaz-Ricart, Maribel, Gratacos, Eduard, and Crispi, Fatima

Published
2021
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22. Severe and malignant hypertension are common in primary atypical hemolytic uremic syndrome

Author

Cavero, Teresa, Arjona, Emilia, Soto, Karina, Caravaca-Fontán, Fernando, Rabasco, Cristina, Bravo, Luis, de la Cerda, Francisco, Martín, Nadia, Blasco, Miquel, Ávila, Ana, Huerta, Ana, Cabello, Virginia, Jarque, Ana, Alcázar, Concepción, Fulladosa, Xavier, Carbayo, Javier, Anaya, Sara, Cobelo, Carmen, Ramos, Natalia, Iglesias, Elena, Baltar, José, Martínez-Gallardo, Rocío, Pérez, Lourdes, Morales, Enrique, González, Roberto, Macía, Manuel, Draibe, Juliana, Pallardó, Luis, Quintana, Luis F., Espinosa, Mario, Barros, Xoana, Pereira, Fernando, Cao, Mercedes, Moreno, Juan Antonio, Rodríguez de Córdoba, Santiago, and Praga, Manuel

Published
2019
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24. Eculizumab Use for Kidney Transplantation in Patients With a Diagnosis of Atypical Hemolytic Uremic Syndrome

Author

Licht, Christoph, Frémeaux-Bacchi, Véronique, Ariceta, Gema, Ardissino, Gianluigi, Fakhouri, Fadi, Greenbaum, Larry, Johnson, Sally, Schaefer, Franz, Scully, Marie Ann, Woodward, Leonard, Ogawa, Masayo, Gasteyger, Christoph, Blasco, Miquel, Cresseri, Donata, Generolova, Galina, Webb, Nicholas, Hirt-Minkowski, Patricia, Kozlovskaya, Natalya Lvovna, Landau, Danny, Lapeyraque, Anne-Laure, Loirat, Chantal, Mache, Christoph, Malina, Michal, Martola, Leena, Massart, Annick, Rondeau, Eric, Sartz, Lisa, Siedlecki, Andrew M., Isbel, Nicole, Vande Walle, Johan, James Eggleston, Jennifer, and Cohen, David J.

Published
2019
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25. On the relevance of thrombomodulin variants in atypical hemolytic uremic syndrome

Author

Instituto de Salud Carlos III, Instituto de Investigación Sanitaria Puerta de Hierro, Ministerio de Economía y Competitividad (España), Comunidad de Madrid, Huerta, Ana [0000-0003-3342-7628], Arjona, Emilia [0000-0002-0753-3657], Portoles, Jose [0000-0002-2114-1385], Lopez-Sanchez, Paula [0000-0002-4332-5759], Cavero, Teresa [0000-0001-5187-9906], Fernandez-Cusicanqui, Jeanette [0000-0002-2369-2324], Blasco, Miquel [0000-0003-0789-7992], Cabello, Virginia [0000-0002-0877-5498], Calvo, Natividad [0000-0003-4031-4816], Díaz-Encarnación, Montserrat M. [0000-0001-5172-3370], Herrero-Goñi, Maria [0000-0001-6501-0830], Ramos, Natalia [0000-0001-9832-326X], Rodríguez de Córdoba, Santiago [0000-0001-6401-1874], Huerta, Ana, Arjona, Emilia, Portoles, Jose, Lopez-Sanchez, Paula, Cavero, Teresa, Fernandez-Cusicanqui, Jeanette, Blasco, Miquel, Cabello, Virginia, Calvo, Natividad, Díaz-Encarnación, Montserrat M., Herrero-Goñi, Maria, Aguirre, Mireia, Elías, Sandra, Alcaide, Maria Paz, Ramos, Natalia, Sellares, Joana, Rodríguez de Córdoba, Santiago, Instituto de Salud Carlos III, Instituto de Investigación Sanitaria Puerta de Hierro, Ministerio de Economía y Competitividad (España), Comunidad de Madrid, Huerta, Ana [0000-0003-3342-7628], Arjona, Emilia [0000-0002-0753-3657], Portoles, Jose [0000-0002-2114-1385], Lopez-Sanchez, Paula [0000-0002-4332-5759], Cavero, Teresa [0000-0001-5187-9906], Fernandez-Cusicanqui, Jeanette [0000-0002-2369-2324], Blasco, Miquel [0000-0003-0789-7992], Cabello, Virginia [0000-0002-0877-5498], Calvo, Natividad [0000-0003-4031-4816], Díaz-Encarnación, Montserrat M. [0000-0001-5172-3370], Herrero-Goñi, Maria [0000-0001-6501-0830], Ramos, Natalia [0000-0001-9832-326X], Rodríguez de Córdoba, Santiago [0000-0001-6401-1874], Huerta, Ana, Arjona, Emilia, Portoles, Jose, Lopez-Sanchez, Paula, Cavero, Teresa, Fernandez-Cusicanqui, Jeanette, Blasco, Miquel, Cabello, Virginia, Calvo, Natividad, Díaz-Encarnación, Montserrat M., Herrero-Goñi, Maria, Aguirre, Mireia, Elías, Sandra, Alcaide, Maria Paz, Ramos, Natalia, Sellares, Joana, and Rodríguez de Córdoba, Santiago

Published
2023

26. Thrombotic microangiopathy in patients with malignant hypertension

Author

Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Comunidad de Madrid, Red Española de Investigación Renal, Cavero, Teresa [0000-0001-5187-9906], Auñón, Pilar [0000-0001-8017-0090], Caravaca-Fontán, Fernando [0000-0002-5830-9663], Trujillo, Hernando [0000-0002-3520-1422], Arjona, Emilia [0000-0002-0753-3657], Morales, Enrique [0000-0002-5824-6973], Guillén, Elena [0000-0002-5687-5549], Blasco, Miquel [0000-0003-0789-7992], Cao, Mercedes [0000-0002-8389-1800], Huerta, Ana [0000-0003-3342-7628], Rubio, Esther [0000-0002-6038-2827], Barros, Xoana [0000-0001-9690-9769], Goicoechea de Jorge, Elena [0000-0002-4978-2483], Rodríguez de Córdoba, Santiago [0000-0001-6401-1874], Praga, Manuel [0000-0001-9270-1071], Cavero, Teresa, Auñón, Pilar, Caravaca-Fontán, Fernando, Trujillo, Hernando, Arjona, Emilia, Morales, Enrique, Guillén, Elena, Blasco, Miquel, Rabasco, Cristina, Espinosa, Mario, Blanco, Marta, Rodríguez-Magariños, Catuxa, Cao, Mercedes, Ávila, Ana, Huerta, Ana, Rubio, Esther, Cabello-Chaves, Virginia, Barros, Xoana, Goicoechea de Jorge, Elena, Rodríguez de Córdoba, Santiago, Praga, Manuel, Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Comunidad de Madrid, Red Española de Investigación Renal, Cavero, Teresa [0000-0001-5187-9906], Auñón, Pilar [0000-0001-8017-0090], Caravaca-Fontán, Fernando [0000-0002-5830-9663], Trujillo, Hernando [0000-0002-3520-1422], Arjona, Emilia [0000-0002-0753-3657], Morales, Enrique [0000-0002-5824-6973], Guillén, Elena [0000-0002-5687-5549], Blasco, Miquel [0000-0003-0789-7992], Cao, Mercedes [0000-0002-8389-1800], Huerta, Ana [0000-0003-3342-7628], Rubio, Esther [0000-0002-6038-2827], Barros, Xoana [0000-0001-9690-9769], Goicoechea de Jorge, Elena [0000-0002-4978-2483], Rodríguez de Córdoba, Santiago [0000-0001-6401-1874], Praga, Manuel [0000-0001-9270-1071], Cavero, Teresa, Auñón, Pilar, Caravaca-Fontán, Fernando, Trujillo, Hernando, Arjona, Emilia, Morales, Enrique, Guillén, Elena, Blasco, Miquel, Rabasco, Cristina, Espinosa, Mario, Blanco, Marta, Rodríguez-Magariños, Catuxa, Cao, Mercedes, Ávila, Ana, Huerta, Ana, Rubio, Esther, Cabello-Chaves, Virginia, Barros, Xoana, Goicoechea de Jorge, Elena, Rodríguez de Córdoba, Santiago, and Praga, Manuel

Abstract

Background: Thrombotic microangiopathy (TMA) is a complication of malignant hypertension (mHTN) attributed to high blood pressure (BP). However, no studies have investigated in patients with mHTN of different aetiologies whether the presence of TMA is associated with specific causes of mHTN., Methods: We investigated the presence of TMA (microangiopathic haemolytic anaemia and thrombocytopenia) in a large and well-characterized cohort of 199 patients with mHTN of different aetiologies [primary HTN 44%, glomerular diseases 16.6%, primary atypical haemolytic uraemic syndrome (aHUS) 13.1%, renovascular HTN 9.5%, drug-related HTN 7%, systemic diseases 5.5%, endocrine diseases 4.5%]. Outcomes of the study were kidney recovery and kidney failure., Results: Patients with TMA [40 cases (20.1%)] were younger, were more likely female and had lower BP levels and worse kidney function at presentation. Their underlying diseases were primary aHUS (60%), drug-related mHTN (15%), glomerular diseases [all of them immunoglobulin A nephropathy (IgAN); 10%], systemic diseases (10%) and primary HTN (5%). The presence of TMA was 92.3% in primary aHUS, 42.9% in drug-related HTN, 36.4% in systemic diseases, 12.1% in glomerular diseases and 2.3% in primary HTN. No patient with renovascular HTN or mHTN caused by endocrine diseases developed TMA, despite BP levels as high as patients with TMA. A higher proportion of TMA patients developed kidney failure as compared with patients without TMA (56.4% versus 38.9%, respectively)., Conclusions: The presence of TMA in patients with mHTN should guide the diagnosis towards primary aHUS, drug-related mHTN, some systemic diseases and IgAN, while it is exceptional in other causes of mHTN.

Published
2023

27. Clinical and genetic predictors of atypical hemolytic uremic syndrome phenotype and outcome

Author

Blasco, Miquel, Cresseri, Donata, Generolova, Galina, Webb, Nicholas, Hirt-Minkowski, Patricia, Lvovna Kozlovskaya, Natalya, Landau, Danny, Lapeyraque, Anne-Laure, Loirat, Chantal, Mache, Christoph, Malina, Michal, Martola, Leena, Massart, Annick, Rondeau, Eric, Siedlecki, Andrew, Sartz, Lisa, Schaefer, Franz, Ardissino, Gianluigi, Ariceta, Gema, Fakhouri, Fadi, Scully, Marie, Isbel, Nicole, Lommelé, Åsa, Kupelian, Varant, Gasteyger, Christoph, Greenbaum, Larry A., Johnson, Sally, Ogawa, Masayo, Licht, Christoph, Vande Walle, Johan, and Frémeaux-Bacchi, Véronique

Published
2018
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28. A retrospective study of pregnancy-associated atypical hemolytic uremic syndrome

Author

Huerta, Ana, Arjona, Emilia, Portoles, Jose, Lopez-Sanchez, Paula, Rabasco, Cristina, Espinosa, Mario, Cavero, Teresa, Blasco, Miquel, Cao, Mercedes, Manrique, Joaquin, Cabello-Chavez, Virginia, Suñer, Marta, Heras, Manuel, Fulladosa, Xavier, Belmar, Lara, Sempere, Amparo, Peralta, Carmen, Castillo, Lorena, Arnau, Alvaro, Praga, Manuel, and Rodriguez de Cordoba, Santiago

Published
2018
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29. On the relevance of thrombomodulin variants in atypical hemolytic uremic syndrome

Author

Huerta, Ana, primary, Arjona, Emi, additional, Portoles, Jose, additional, Lopez-Sanchez, Paula, additional, Cavero, Teresa, additional, Fernandez-Cusicanqui, Jeanette, additional, Blasco, Miquel, additional, Cabello, Virginia, additional, Calvo, Natividad, additional, Diaz, Montserrat, additional, Herrero-Goñi, Maria, additional, Aguirre, Mireia, additional, Elías, Sandra, additional, Alcaide, Maria Paz, additional, Ramos, Natalia, additional, Sellares, Joana, additional, and Rodríguez de Córdoba, Santiago, additional

Published
2023
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30. Association of obesity with 3-month mortality in kidney failure patients with COVID-19

Author

Tantisattamo, Ekamol, Imhof, Celine, Jager, Kitty J., Hilbrands, Luuk B., Guidotti, Rebecca, Islam, Mahmud, Katicic, Dajana, Konings, Constantijn, Molenaar, Femke M., Nistor, Ionut, Noordzij, Marlies, Rodríguez Ferrero, Mariá Luisa, Verhoeven, Martine A. M., de Vries, Aiko P. J., Kalantar-Zadeh, Kamyar, Gansevoort, Ron T., Vart, Priya, van der Net, Jeroen B., Essig, Marie, du Buf-Vereijken, Peggy W. G., van Ginneken, Betty, Maas, Nanda, van Jaarsveld, Brigit C., Bemelman, Frederike J., Klingenberg-Salahova, Farah, Heenan-Vos, Frederiek, Vervloet, Marc G., Nurmohamed, Azam, Vogt, Liffert, Abramowicz, Daniel, Verhofstede, Sabine, Maoujoud, Omar, Malfait, Thomas, Fialova, Jana, Melilli, Edoardo, Favà, Alexandre, Cruzado, Josep M., Perez, Nuria Montero, Lips, Joy, Krepel, Harmen, Adilovic, Harun, Radulescu, Daniela, Hengst, Maaike, Rydzewski, Andrzej, Braconnier, Philippe, Weis, Daniel, Gellert, Ryszard, Oliveira, Joaõ, Alferes, Daniela G., Zakharova, Elena V., Ambuehl, Patrice Max, Walker, Andrea, Lepeytre, Fanny, Rabate, Clementine, Rostoker, Guy, Marques, Sofia, Azasevac, Tijana, Majstorovic, Gordana Strazmester, ten Dam, Marc, Krüger, Thilo, Brzosko, Szymon, Liakopoulos, Vassilios, Zanen, Adriaan L., Logtenberg, Susan J. J., Fricke, Lutz, Kuryata, Olexandr, Slebe, Jeroen J. P., Elhafeez, Samar Abd, Kemlin, Delphine, van de Wetering, Jacqueline, Reinders, Marlies E. J., Hesselink, Dennis A., Kal-van Gestel, J., Eiselt, Jaromir, Kielberger, Lukas, el-Wakil, Hala S., Logan, Ian, Canal, Cristina, Facundo, Carme, Ramos, Ana M., Debska-Slizien, Alicja, Veldhuizen, Nicoline M. H., Tigka, Eirini, Konsta, Maria Anna Polyzou, Panagoutsos, Stylianos, Mallamaci, Francesca, Postorino, Adele, Cambareri, Francesco, Matceac, Irina, Covic, Adrian, Groeneveld, J. H. M., Jousma, Jolanda, van Buren, Marjolijn, Diekmann, Fritz, Oppenheimer, Federico, Blasco, Miquel, Pereira, Tiago Assis, Santos, Augusto Cesar S., Arias-Cabrales, Carlos, Crespo, Marta, Llinàs-Mallol, Laura, Buxeda, Anna, Tàrrega, Carla Burballa, Redondo-Pachon, Dolores, Jimenez, Maria Dolores Arenas, Mendoza-Valderrey, Alberto, Martins, Ana Cristina, Mateus, Catarina, Alvila, Goncalo, Laranjinha, Ivo, Hofstra, Julia M., Siezenga, Machiel A., Franco, Antonio, Arroyo, David, Castellano, Sandra, Manzanos, Sagrario Balda, Haridian Sosa Barrios, R., Lemahieu, Wim, Bartelet, Karlijn, Dirim, Ahmet Burak, Demir, Erol, Sever, Mehmet Sukru, Turkmen, Aydin, Safak, Seda, Hollander, Daan A. M. J., Büttner, Stefan, Meziyerh, Soufian, van der Helm, Danny, Mallat, Marko, Bouwsma, Hanneke, Sridharan, Sivakumar, Petruliene, Kristina, Maloney, Sharon-Rose, Verberk, Iris, van der Sande, Frank M., Christiaans, Maarten H. L., Hemmelder, Marc H., Kumar, Mohan N., di Luca, Marina, Tuǧlular, Serhan Z., Ziekenhuis, Martini, Kramer, Andrea B., Beerenhout, Charles, Luik, Peter T., Kerschbaum, Julia, Tiefenthaler, Martin, Watschinger, Bruno, Adema, Aaltje Y., Stepanov, Vadim A., Zulkarnaev, Alexey B., Turkmen, Kultigin, Gandolfini, Ilaria, Maggiore, Umberto, Fliedner, Anselm, Åsberg, Anders, Mjoen, Geir, Miyasato, Hitoshi, de Fijter, Carola W. H., Mongera, Nicola, Pini, Stefano, de Biase, Consuelo, Kerckhoffs, Angele, Els van de Logt, Anne, Maas, Rutger, Duivenvoorden, Raphaël, Lebedeva, Olga, Lopez, Veronica, Reichert, Louis J. M., Verhave, Jacobien, Titov, Denis, Parshina, Ekaterina V., Zanoli, Luca, Marcantoni, Carmelita, van Kempen, Gijs, van Gils-Verrij, Liesbeth E. A., Harty, John C., Meurs, Marleen, Myslak, Marek, Battaglia, Yuri, Lentini, Paolo, den Deurwaarder, Edwin, Stendahl, Maria, Rahimzadeh, Hormat, Schouten, Marcel, Rychlik, Ivan, Cabezas-Reina, Carlos J., Roca, Ana Maria, Nauta, Ferdau, Sahin, Idris, Goffin, Eric, Kanaan, Nada, Labriola, Laura, Devresse, Arnaud, Diaz-Mareque, Anabel, Coca, Armando, de Arriba, Gabriel, Meijers, Björn K. I., Naesens, Maarten, Kuypers, Dirk, Desschans, Bruno, Tonnerlier, Annelies, Wissing, Karl M., Dedinska, Ivana, Pessolano, Giuseppina, Malik, Shafi, Dounousi, Evangelia, Papachristou, Evangelos, Berger, Stefan P., Meijer, Esther, Sanders, Jan Stephan F., Franssen, Casper F. M., Özyilmaz, Akin, Ponikvar, Jadranka Buturović, Pernat, Andreja Marn, Kovac, Damjan, Arnol, Miha, Ekart, Robert, Abrahams, Alferso C., van Zuilen, Arjan D., Meijvis, Sabine C. A., Dolmans, Helma, Esposito, Pasquale, Krzesinski, Jean-Marie, Barahira, Jean Damacène, Gallieni, Maurizio, Martin-Moreno, Paloma Leticia, Guglielmetti, Gabriele, Guzzo, Gabriella, Toapanta, Nestor, Soler, Maria Jose, Luik, Antinus J., van Kuijk, Willi H. M., Stikkelbroeck, Lonneke W. H., Hermans, Marc M. H., Rimsevicius, Laurynas, Righetti, Marco, Heitink-ter Braak, Nicole, Medical Informatics, APH - Aging & Later Life, APH - Quality of Care, APH - Global Health, ACS - Pulmonary hypertension & thrombosis, Nephrology, ACS - Microcirculation, APH - Health Behaviors & Chronic Diseases, Clinical sciences, UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, ACS - Diabetes & metabolism, Internal Medicine, Cardiovascular Centre (CVC), Groningen Kidney Center (GKC), van der Net, Jeroen B, Essig, Marie, du Buf-Vereijken, Peggy W G, van Ginneken, Betty, Maas, Nanda, van Jaarsveld, Brigit C, Bemelman, Frederike J, Klingenberg-Salahova, Farah, Heenan-Vos, Frederiek, Vervloet, Marc G, Nurmohamed, Azam, Vogt, Liffert, Abramowicz, Daniel, Verhofstede, Sabine, Maoujoud, Omar, Malfait, Thomas, Fialova, Jana, Melilli, Edoardo, Favà, Alexandre, Cruzado, Josep M, Perez, Nuria Montero, Lips, Joy, Krepel, Harmen, Adilovic, Harun, Radulescu, Daniela, Hengst, Maaike, Rydzewski, Andrzej, Braconnier, Philippe, Weis, Daniel, Gellert, Ryszard, Oliveira, João, Alferes, Daniela G, Zakharova, Elena V, Ambuehl, Patrice Max, Walker, Andrea, Lepeytre, Fanny, Rabaté, Clémentine, Rostoker, Guy, Marques, Sofia, Azasevac, Tijana, Majstorovic, Gordana Strazmester, Ten Dam, Marc, Krüger, Thilo, Brzosko, Szymon, Liakopoulos, Vassilios, Zanen, Adriaan L, Logtenberg, Susan J J, Fricke, Lutz, Kuryata, Olexandr, Slebe, Jeroen J P, ElHafeez, Samar Abd, Kemlin, Delphine, van de Wetering, Jacqueline, Reinders, Marlies E J, Hesselink, Dennis A, Kal-van Gestel, J., Eiselt, Jaromir, Kielberger, Lukas, El-Wakil, Hala S, Logan, Ian, Canal, Cristina, Facundo, Carme, Ramos, Ana M, Debska-Slizien, Alicja, Veldhuizen, Nicoline M H, Tigka, Eirini, Konsta, Maria Anna Polyzou, Panagoutsos, Stylianos, Mallamaci, Francesca, Postorino, Adele, Cambareri, Francesco, Matceac, Irina, Covic, Adrian, Groeneveld, J H M, Jousma, Jolanda, van Buren, Marjolijn, Diekmann, Fritz, Oppenheimer, Federico, Blasco, Miquel, Pereira, Tiago Assis, Santos, Augusto Cesar S, Arias-Cabrales, Carlos, Crespo, Marta, Llinàs-Mallol, Laura, Buxeda, Anna, Tàrrega, Carla Burballa, Redondo-Pachon, Dolores, Jimenez, Maria Dolores Arenas, Mendoza-Valderrey, Alberto, Martins, Ana Cristina, Mateus, Catarina, Alvila, Goncalo, Laranjinha, Ivo, Hofstra, Julia M, Siezenga, Machiel A, Franco, Antonio, Arroyo, David, Castellano, Sandra, Manzanos, Sagrario Balda, Haridian Sosa Barrios, R., Lemahieu, Wim, Bartelet, Karlijn, Dirim, Ahmet Burak, Demir, Erol, Sever, Mehmet Sukru, Turkmen, Aydin, Şafak, Seda, Hollander, Daan A M J, Büttner, Stefan, Meziyerh, Soufian, van der Helm, Danny, Mallat, Marko, Bouwsma, Hanneke, Sridharan, Sivakumar, Petrulienė, Kristina, Maloney, Sharon-Rose, Verberk, Iris, van der Sande, Frank M, Christiaans, Maarten H L, Hemmelder, Marc H, Kumar N, Mohan, Di Luca, Marina, Tuğlular, Serhan Z, Ziekenhuis, Martini, Kramer, Andrea B, Beerenhout, Charles, Luik, Peter T, Kerschbaum, Julia, Tiefenthaler, Martin, Watschinger, Bruno, Adema, Aaltje Y, Stepanov, Vadim A, Zulkarnaev, Alexey B, Turkmen, Kultigin, Gandolfini, Ilaria, Maggiore, Umberto, Fliedner, Anselm, Åsberg, Anders, Mjoen, Geir, Miyasato, Hitoshi, de Fijter, Carola W H, Mongera, Nicola, Pini, Stefano, de Biase, Consuelo, Kerckhoffs, Angele, Els van de Logt, Anne, Maas, Rutger, Duivenvoorden, Raphaël, Lebedeva, Olga, Lopez, Veronica, Reichert, Louis J M, Verhave, Jacobien, Titov, Denis, Parshina, Ekaterina V, Zanoli, Luca, Marcantoni, Carmelita, van Kempen, Gijs, van Gils-Verrij, Liesbeth E A, Harty, John C, Meurs, Marleen, Myslak, Marek, Battaglia, Yuri, Lentini, Paolo, den Deurwaarder, Edwin, Stendahl, Maria, Rahimzadeh, Hormat, Schouten, Marcel, Rychlik, Ivan, Cabezas-Reina, Carlos J, Roca, Ana Maria, Nauta, Ferdau, Sahin, İdris, Goffin, Eric, Kanaan, Nada, Labriola, Laura, Devresse, Arnaud, Diaz-Mareque, Anabel, Coca, Armando, de Arriba, Gabriel, Meijers, Björn K I, Naesens, Maarten, Kuypers, Dirk, Desschans, Bruno, Tonnerlier, Annelies, Wissing, Karl M, Dedinska, Ivana, Pessolano, Giuseppina, Malik, Shafi, Dounousi, Evangelia, Papachristou, Evangelos, Berger, Stefan P, Meijer, Esther, Sanders, Jan Stephan F, Franssen, Casper F M, Özyilmaz, Akin, Ponikvar, Jadranka Buturović, Pernat, Andreja Marn, Kovac, Damjan, Arnol, Miha, Ekart, Robert, Abrahams, Alferso C, van Zuilen, Arjan D, Meijvis, Sabine C A, Dolmans, Helma, Esposito, Pasquale, Krzesinski, Jean-Marie, Barahira, Jean Damacène, Gallieni, Maurizio, Martin-Moreno, Paloma Leticia, Guglielmetti, Gabriele, Guzzo, Gabriella, Toapanta, Nestor, Soler, Maria Jose, Luik, Antinus J, van Kuijk, Willi H M, Stikkelbroeck, Lonneke W H, Hermans, Marc M H, Rimševičius, Laurynas, Righetti, Marco, and Heitink-Ter Braak, Nicole

Subjects
Transplantation, COVID-19, infectious diseases, mortality, DIALYSIS PATIENTS, kidney failure, BODY-MASS INDEX, obesity paradox, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], TRANSPLANT, SDG 3 - Good Health and Well-being, Nephrology, ERACODA, reverse epidemiology, Renal disorders Radboud Institute for Health Sciences [Radboudumc 11]
Abstract

Background In the general population with coronavirus disease 2019 (COVID-19), obesity is associated with an increased risk of mortality. Given the typically observed obesity paradox among patients on kidney function replacement therapy (KFRT), especially dialysis patients, we examined the association of obesity with mortality among dialysis patients or living with a kidney transplant with COVID-19. Methods Data from the European Renal Association COVID-19 Database (ERACODA) were used. KFRT patients diagnosed with COVID-19 between 1 February 2020 and 31 January 2021 were included. The association of Quetelet's body mass index (BMI) (kg/m2), divided into: Results In 3160 patients on KFRT (mean age: 65 years, male: 61%), 99 patients were lean, 1151 normal weight (reference), 1160 overweight, 525 obese I and 225 obese II/III. During follow-up of 3 months, 28, 20, 21, 23 and 27% of patients died in these categories, respectively. In the fully adjusted model, the hazard ratios (HRs) for 3-month mortality were 1.65 [95% confidence interval (CI): 1.10, 2.47], 1 (ref.), 1.07 (95% CI: 0.89, 1.28), 1.17 (95% CI: 0.93, 1.46) and 1.71 (95% CI: 1.27, 2.30), respectively. Results were similar among dialysis patients (N = 2343) and among those living with a kidney transplant (N = 817) (Pinteraction = 0.99), but differed by sex (Pinteraction = 0.019). In males, the HRs for the association of aforementioned BMI categories with 3-month mortality were 2.07 (95% CI: 1.22, 3.52), 1 (ref.), 0.97 (95% CI: 0.78. 1.21), 0.99 (95% CI: 0.74, 1.33) and 1.22 (95% CI: 0.78, 1.91), respectively, and in females corresponding HRs were 1.34 (95% CI: 0.70, 2.57), 1 (ref.), 1.31 (95% CI: 0.94, 1.85), 1.54 (95% CI: 1.05, 2.26) and 2.49 (95% CI: 1.62, 3.84), respectively. Conclusion In KFRT patients with COVID-19, on dialysis or a kidney transplant, obesity is associated with an increased risk of mortality at 3 months. This is in contrast to the obesity paradox generally observed in dialysis patients. Additional studies are required to corroborate the sex difference in the association of obesity with mortality.

Published
2022
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33. Significance of clinical‐immunological patterns and diagnostic yield of biopsies in microscopic polyangiitis and granulomatosis with polyangiitis.

Author

Fernandes‐Serodio, João, Prieto‐González, Sergio, Espígol‐Frigolé, Georgina, Ríos‐Garcés, Roberto, Gómez‐Caverzaschi, Verónica, Araújo, Olga, Espinosa, Gerard, Jordà‐Sánchez, Raül, Alba, Marco A., Quintana, Luis, Blasco, Miquel, Guillen, Elena, Viñas, Odette, Ruiz‐Ortiz, Estíbaliz, Pelegrín, Laura, Sainz de la Maza, Maite, Sánchez‐Dalmau, Bernardo, García‐Herrera, Adriana, Solé, Manel, and Castillo, Paola

Subjects
MICROSCOPIC polyangiitis, GRANULOMATOSIS with polyangiitis, ANTINEUTROPHIL cytoplasmic antibodies, INTERSTITIAL lung diseases, MORTALITY risk factors
Abstract

Background: Microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA) are the two major antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV). Objectives: To characterize a homogenous AAV cohort and to assess the impact of clinicopathological profiles and ANCA serotypes on clinical presentation and prognosis. Clinical differences in GPA patients according to ANCA serotype and the diagnostic yield for vasculitis of biopsies in different territories were also investigated. Results: This retrospective study (2000–2021) included 152 patients with AAV (77 MPA/75 GPA). MPA patients (96.1% myeloperoxidase [MPO]–ANCA and 2.6% proteinase 3 [PR3]–ANCA) presented more often with weight loss, myalgia, renal involvement, interstitial lung disease (ILD), cutaneous purpura, and peripheral nerve involvement. Patients with GPA (44% PR3–ANCA, 33.3% MPO, and 22.7% negative/atypical ANCA) presented more commonly with ear, nose, and throat and eye/orbital manifestations, more relapses, and higher survival than patients with MPA. GPA was the only independent risk factor for relapse. Poor survival predictors were older age at diagnosis and peripheral nerve involvement. ANCA serotypes differentiated clinical features in a lesser degree than clinical phenotypes. A mean of 1.5 biopsies were performed in 93.4% of patients in different territories. Overall, vasculitis was identified in 80.3% (97.3% in MPA and 61.8% in GPA) of patients. Conclusions: The identification of GPA presentations associated with MPO–ANCA and awareness of risk factors for relapse and mortality are important to guide proper therapeutic strategies in AAV patients. Biopsies of different affected territories should be pursued in difficult‐to‐diagnose patients based on their significant diagnostic yield. [ABSTRACT FROM AUTHOR]

Published
2024
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34. In Vitro Proliferation and Cryoconservation of Banana and Plantain Elite Clones

Author

Reyes Guillermo, García José, Piña Fernando, Mendoza Joffre, Sosa Daynet, Noceda Carlos, Blasco Miquel, and Flores José

Subjects
vitrification, cryopreservation, in vitro propagation, musa spp, meristems, Plant culture, SB1-1110
Abstract

Agriculture and modern biotechnology are increasingly becoming interdependent, and many new techniques have brought new opportunities for enhancing production and marketing. Germplasm storage is an alternative for the conservation of plant genetic diversity, contributing to the improvement and maintenance of propagation programs for species of interest. In this work, banana corms were collected as plant material from relatively young commercial plantations of three different cultivars: ‘Williams’, Valery (AAA genome; Cavendish subgroup), and ‘Barraganete’ (AAB genome; Plantain subgroup). Their shoot tips were introduced into in vitro conditions, and subcultured monthly to obtain the required number of shoots. The shoots were subsequently rooted and stimulated to invigoration in order to extract apical meristems (0.8–1.0 mm), which were prepared for cryopreservion in liquid nitrogen (−196 °C) following pre-conditioning in PVS2 vitrification solution. Thereafter, the explants were rapidly thawed and then recovered and regenerated using two different methods – by Panis (2009) and Korneva et al. (2009) – consisting of two different sets of recovery and subsequent regeneration media. Statistical analysis of the results showed that the banana cultivar ‘Williams’ demonstrated higher survival and regeneration rates after cry-opreservation using the Korneva method, whereas in cultivars ‘Valery’ and ‘Barraganete’, there were no significant differences between the tested methods. The ‘Barraganete’ cultivar had the lowest survival and regeneration rates, regardless of the applied method.

Published
2017
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37. Impact of cardiac surgery associated acute kidney injury on 1-year major adverse kidney events

Author

Molina Andújar, Alícia, primary, Escudero, Victor Joaquin, additional, Piñeiro, Gaston J., additional, Lucas, Alvaro, additional, Rovira, Irene, additional, Matute, Purificación, additional, Ibañez, Cristina, additional, Blasco, Miquel, additional, Quintana, Luis F., additional, Sandoval, Elena, additional, Sánchez, Marina Chorda, additional, Quintana, Eduard, additional, and Poch, Esteban, additional

Published
2023
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40. Conceptual design of the AGATA 2π array at LNL

Author

J.J. Valiente-Dobón, R. Menegazzo, A. Goasduff, D. Agguiaro, P. Aguilera, F. Angelini, M. Balogh, D. Bazzacco, J. Benito, G. Benzoni, N. Bez, M. Bolognesi, S. Bottoni, D. Brugnara, S. Carollo, P. Cocconi, A. Cogo, J. Collado, F.C.L. Crespi, A. Ertoprak, R. Escudeiro, F. Galtarossa, E.R. Gamba, A. Gambalonga, B. Góngora Servín, A. Gottardo, A. Gozzelino, M. Gulmini, Z. Huang, T. Marchi, D. Mengoni, P. Modanese, D.R. Napoli, J. Pellumaj, R.M. Pérez-Vidal, S. Pigliapoco, E. Pilotto, L. Ramina, M. Rampazzo, W. Raniero, M. Rebeschini, K. Rezynkina, D. Rosso, M. Scarcioffolo, D. Scarpa, M. Sedlák, R. Smith, N. Toniolo, F. Veronese, V. Volpe, L. Zago, I. Zanon, G. Zhang, R. Abels, M.L. Allegrini, C. Aufranc, G. Baulieu, C. Belkhiria, M. Benettoni, D. Benini, M. Bentley, M. Biasotto, M. Blaizot, J. Blasco Miquel, C. Boiano, A. Boston, H. Boston, A. Boujrad, P. Bourgault, A. Bracco, S. Brambilla, I. Burrows, F. Camera, S. Capra, A. Capsoni, R. Cash, J.V. Civera, E. Clément, S. Coelli, M. Cordwell, L. Corradi, S. Coudert, G. De Angelis, L. De Ruvo, G. Debras, M. Del Fabbro, J. Diklić, N. Dosme, G. Duchene, B. Duclos, J. Dudouet, J. Eberth, S. Elloumi, C. Everett, S. Fantinel, M. Fillinger, E. Fioretto, C. Fransen, A. Gadea, L. Gibelin, V. González, J. Goupil, C. Görgen, A. Grant, K. Green, J. Ha, T. Hartnett, K. Henseler, H. Hess, R. Hirsch, C. Houarner, J. Jacob, T. Joannem, D.S. Judson, N. Karkour, M. Karolak, M. Kebbiri, J. Kieffer, M. Labiche, X. Lafay, P. Le Jeannic, A. Lefevre, E. Legay, F. Legruel, S. Lenzi, S. Leoni, D. Linget, M. Liptrot, A. López-Martens, A. Lotodé, L. Manara, L. Ménager, T. Mijatović, B. Million, A. Minarello, G. Montagnoli, P. Morrall, I. Mullacrane, J. Nyberg, G. Philippon, M. Polettini, F. Popieul, A. Pullia, F. Recchia, P. Reiter, G. Richardt, M. Rocchini, A. Roger, F. Saillant, E. Sanchis, Md.S.R. Laskar, G. Secci, M.-H. Sigward, J. Simpson, N. Solenne, F. Spee, A.M. Stefanini, O. Stézowski, S. Szilner, N. Templeton, Ch. Theisen, S. Thiel, F. Tomasi, S. Tzvetkov, D. Vigano, E. Viscione, O. Wieland, K. Wimmer, G. Wittwer, M. Zielińska, Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Grand Accélérateur National d'Ions Lourds (GANIL), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut Pluridisciplinaire Hubert Curien (IPHC), and Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)

Subjects
AGATA spectrometer, DANTE detector, EUCLIDES detector, LNL facility, Plunger device, PRISMA spectrometer, Pulse shape analysis, TRACE detector, γ-ray tracking, Nuclear and High Energy Physics, Settore FIS/04 - Fisica Nucleare e Subnucleare, ray tracking, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Instrumentation
Abstract

International audience; The Advanced GAmma Tracking Array (AGATA) has been installed at Laboratori Nazionali di Legnaro (LNL), Italy. In this installation, AGATA will consist, at the beginning, of 13 AGATA triple clusters (ATCs) with an angular coverage of 1π, and progressively the number of ATCs will increase up to a 2π angular coverage. This setup will exploit both stable and radioactive ion beams delivered by the Tandem–PIAVE-ALPI accelerator complex and the SPES facility. The new implementation of AGATA at LNL will be used in two different configurations, firstly one coupled to the PRISMA large-acceptance magnetic spectrometer and lately a second one at Zero Degrees, along the beam line. These two configurations will allow us to cover a broad physics program, using different reaction mechanisms, such as Coulomb excitation, fusion-evaporation, transfer and fission at energies close to the Coulomb barrier. These setups have been designed to be coupled with a large variety of complementary detectors such as charged particle detectors, neutron detectors, heavy-ion detectors, high-energy γ-ray arrays, cryogenic and gasjet targets and the plunger device for lifetime measurements. We present in this paper the conceptual design, characteristics and performance figures of this implementation of AGATA at LNL.

Published
2023
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42. Sex differences in COVID-19 mortality risk in patients on kidney function replacement therapy

Author

Vart, Priya, Duivenvoorden, Raphaël, Adema, Aaltje, Covic, Adrian, Finne, Patrik, Braak, Nicole Heijtink-ter, Laine, Kaisa, Noordzij, Marlies, Schouten, Marcel, Jager, Kitty J., Gansevoort, Ron T., van der Net, Jeroen B., Essig, Marie, du Buf-Vereijken, Peggy W. G., van Ginneken, Betty, Maas, Nanda, van Jaarsveld, Brigit C., Bemelman, Frederike J., Klingenberg-Salahova, Farah, Heenan-Vos, Frederiek, Vervloet, Marc G., Nurmohamed, Azam, Vogt, Liffert, Abramowicz, Daniel, Verhofstede, Sabine, Maoujoud, Omar, Malfait, Thomas, Fialova, Jana, Melilli, Edoardo, Favà, Alexandre, Cruzado, Josep M., Perez, Nuria Montero, Lips, Joy, Krepel, Harmen, Adilovic, Harun, Radulescu, Daniela, Hengst, Maaike, Konings, Constantijn, Rydzewski, Andrzej, Braconnier, Philippe, Weis, Daniel, Gellert, Ryszard, Oliveira, João, Alferes, Daniela G., Zakharova, Elena V., Ambühl, Patrice Max, Guidotti, Rebecca, Walker, Andrea, Lepeytre, Fanny, Rabaté, Clémentine, Rostoker, Guy, Marques, Sofia, Azasevac, Tijana, Majstorovic, Gordana Strazmester, Katicic, Dajana, ten Dam, Marc, Krüger, Thilo, Brzosko, Szymon, Liakopoulos, Vassilios, Zanen, Adriaan L., Logtenberg, Susan J. J., Fricke, Lutz, Kuryata, Olexandr, Slebe, Jeroen J. P., ElHafeez, Samar Abd, Kemlin, Delphine, van de Wetering, Jacqueline, Reinders, Marlies E. J., Hesselink, Dennis A., Kal-van Gestel, J., Eiselt, Jaromir, Kielberger, Lukas, El-Wakil, Hala S., Verhoeven, Martine, Logan, Ian, Canal, Cristina, Facundo, Carme, Ramos, Ana M., Debska-Slizien, Alicja, Veldhuizen, Nicoline M. H., Tigka, Eirini, Konsta, Maria Anna Polyzou, Panagoutsos, Stylianos, Mallamaci, Francesca, Postorino, Adele, Cambareri, Francesco, Matceac, Irina, Nistor, Ionut, Groeneveld, J. H.M., Jousma, Jolanda, van Buren, Marjolijn, Diekmann, Fritz, Oppenheimer, Federico, Blasco, Miquel, Pereira, Tiago Assis, Santos, Augusto Cesar S., Arias-Cabrales, Carlos, Crespo, Marta, Llinàs-Mallol, Laura, Buxeda, Anna, Tàrrega, Carla Burballa, Redondo-Pachon, Dolores, Jimenez, Maria Dolores Arenas, Mendoza-Valderrey, Alberto, Martins, Ana Cristina, Mateus, Catarina, Alvila, Goncalo, Laranjinha, Ivo, Hofstra, Julia M., Siezenga, Machiel A., Franco, Antonio, Arroyo, David, Castellano, Sandra, Rodríguez-Ferrero, Maria Luisa, Manzanos, Sagrario Balda, Barrios, R. Haridian Sosa, Lemahieu, Wim, Bartelet, Karlijn, Dirim, Ahmet Burak, Demir, Erol, Sever, Mehmet Sukru, Turkmen, Aydin, Şafak, Seda, Hollander, Daan A. M. J., Büttner, Stefan, de Vries, Aiko P. J., Meziyerh, Soufian, van der Helm, Danny, Mallat, Marko, Bouwsma, Hanneke, Sridharan, Sivakumar, Petrulienė, Kristina, Maloney, Sharon-Rose, Verberk, Iris, van der Sande, Frank M., Christiaans, Maarten H. L., Hemmelder, Marc H., MohanKumar, N., Di Luca, Marina, Tuğlular, Serhan Z., Kramer, Andrea B., Beerenhout, Charles, Luik, Peter T., Kerschbaum, Julia, Tiefenthaler, Martin, Watschinger, Bruno, Stepanov, Vadim A., Zulkarnaev, Alexey B., Turkmen, Kultigin, Gandolfini, Ilaria, Maggiore, Umberto, Fliedner, Anselm, Åsberg, Anders, Mjoen, Geir, Miyasato, Hitoshi, de Fijter, Carola W. H., Mongera, Nicola, Pini, Stefano, de Biase, Consuelo, Kerckhoffs, Angele, van de Logt, Anne Els, Maas, Rutger, Hilbrands, Luuk B., Lebedeva, Olga, Lopez, Veronica, Reichert, Louis J. M., Verhave, Jacobien, Titov, Denis, Parshina, Ekaterina V., Zanoli, Luca, Marcantoni, Carmelita, van Kempen, Gijs, van Gils-Verrij, Liesbeth E. A., Harty, John C., Meurs, Marleen, Myslak, Marek, Battaglia, Yuri, Lentini, Paolo, den Deurwaarder, Edwin, Stendahl, Maria, Rahimzadeh, Hormat, Rychlik, Ivan, Cabezas-Reina, Carlos J., Roca, Ana Maria, Nauta, Ferdau, Sahin, İdris, Goffin, Eric, Kanaan, Nada, Labriola, Laura, Devresse, Arnaud, Diaz-Mareque, Anabel, Coca, Armando, de Arriba, Gabriel, Meijers, Björn K. I., Naesens, Maarten, Kuypers, Dirk, Desschans, Bruno, Tonnerlier, Annelies, Wissing, Karl M., Dedinska, Ivana, Pessolano, Giuseppina, Malik, Shafi, Dounousi, Evangelia, Papachristou, Evangelos, Berger, Stefan P., Sanders, Jan Stephan F., Franssen, Casper F. M., Özyilmaz, Akin, Ponikvar, Jadranka Buturović, Pernat, Andreja Marn, Kovac, Damjan, Arnol, Miha, Ekart, Robert, Abrahams, Alferso C., Molenaar, Femke M., van Zuilen, Arjan D., Meijvis, Sabine C. A., Dolmans, Helma, Tantisattamo, Ekamol, Esposito, Pasquale, Krzesinski, Jean-Marie, Barahira, Jean Damacène, Gallieni, Maurizio, Martin-Moreno, Paloma Leticia, Guglielmetti, Gabriele, Guzzo, Gabriella, Toapanta, Nestor, Soler, Maria Jose, Luik, Antinus J., van Kuijk, Willi H. M., Stikkelbroeck, Lonneke W. H., Hermans, Marc M. H., Rimševičius, Laurynas, Righetti, Marco, Islam, Mahmud, Clinical sciences, Nephrology, Groningen Kidney Center (GKC), Cardiovascular Centre (CVC), Groningen Institute for Organ Transplantation (GIOT), Medical Informatics, APH - Aging & Later Life, APH - Quality of Care, APH - Global Health, ACS - Pulmonary hypertension & thrombosis, AII - Inflammatory diseases, ACS - Microcirculation, APH - Health Behaviors & Chronic Diseases, Internal Medicine, Department of Medicine, Clinicum, University of Helsinki, Helsinki University Hospital Area, ACS - Diabetes & metabolism, UCL - SSS/IREC/NEFR - Pôle de Néphrologie, and UCL - (SLuc) Service de néphrologie

Subjects
Male, kidney, Transplant, infectious diseases, Kidney, All institutes and research themes of the Radboud University Medical Center, COVID‐19, Renal Dialysis, Risk Factors, risk factors, Humans, Eracoda, Aged, Sex Characteristics, Multidisciplinary, Dialysis patients, Kidney Transplantation/adverse effects, COVID-19, Middle Aged, Kidney Transplantation, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Nephrology, 3121 General medicine, internal medicine and other clinical medicine, mortality risk, Immunosuppressive Agents/therapeutic use, Female, Immunosuppressive Agents
Abstract

In the general population with COVID-19, the male sex is an established risk factor for mortality, in part due to a more robust immune response to COVID-19 in women. Because patients on kidney function replacement therapy (KFRT) have an impaired immune response, especially kidney transplant recipients due to their use of immunosuppressants, we examined whether the male sex is still a risk factor for mortality among patients on KFRT with COVID-19. From the European Renal Association COVID-19 Database (ERACODA), we examined patients on KFRT with COVID-19 who presented between February 1st, 2020, and April 30th, 2021. 1204 kidney transplant recipients (male 62.0%, mean age 56.4 years) and 3206 dialysis patients (male 61.8%, mean age 67.7 years) were examined. Three-month mortality in kidney transplant recipients was 16.9% in males and 18.6% in females (p = 0.31) and in dialysis patients 27.1% in males and 21.9% in females (p = 0.001). The adjusted HR for the risk of 3-month mortality in males (vs females) was 0.89 (95% CI 65, 1.23, p = 0.49) in kidney transplant recipients and 1.33 (95% CI 1.13, 1.56, p = 0.001) in dialysis patients (pinteraction = 0.02). In a fully adjusted model, the aHR for the risk of 3-month mortality in kidney transplant recipients (vs. dialysis patients) was 1.39 (95% CI 1.02, 1.89, p = 0.04) in males and 2.04 (95% CI 1.40, 2.97, p interaction = 0.02). In patients on KFRT with COVID-19, the male sex is not a risk factor for mortality among kidney transplant recipients but remains a risk factor among dialysis patients. The use of immunosuppressants in kidney transplant recipients, among other factors, may have narrowed the difference in the immune response to COVID-19 between men and women, and therefore reduced the sex difference in COVID-19 mortality risk.

Published
2022
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43. Creatine Kinase Elevation in Autosomal Dominant Polycystic Kidney Disease Patients on Tolvaptan Treatment

Author

Rodríguez-Espinosa, Diana, primary, Broseta, José Jesús, additional, Bastida, Carla, additional, Álvarez-Mora, María Isabel, additional, Nicolau, Carlos, additional, Alvarez, Cristina, additional, Agraz-Pamplona, Irene, additional, Sánchez-Baya, Maya, additional, Furlano, Mónica, additional, Ruiz, César, additional, Quintana, Luis F., additional, Piñeiro, Gastón J., additional, Poch, Esteban, additional, Torra-Balcells, Roser, additional, and Blasco, Miquel, additional

Published
2022
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44. Eculizumab in secondary atypical haemolytic uraemic syndrome

Author

Cavero, Teresa, Rabasco, Cristina, López, Antía, Román, Elena, Ávila, Ana, Sevillano, Ángel, Huerta, Ana, Rojas-Rivera, Jorge, Fuentes, Carolina, Blasco, Miquel, Jarque, Ana, García, Alba, Mendizabal, Santiago, Gavela, Eva, Macía, Manuel, Quintana, Luis F., Romera, Ana María, Borrego, Josefa, Arjona, Emi, Espinosa, Mario, Portolés, José, Gracia-Iguacel, Carolina, González-Parra, Emilio, Aljama, Pedro, Morales, Enrique, Cao, Mercedes, de Córdoba, Santiago Rodríguez, and Praga, Manuel

Published
2017
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45. Autosomal dominant polycystic kidney disease in young adults.

Author

Martínez, Víctor, Furlano, Mónica, Sans, Laia, Pulido, Lissett, García, Rebeca, Pérez-Gómez, María Vanessa, Sánchez-Rodríguez, Jinny, Blasco, Miquel, Castro-Alonso, Cristina, Fernández-Fresnedo, Gema, Robles, Nicolás Roberto, Valenzuela, María Pau, Naranjo, Javier, Martín, Nadia, Pilco, Melissa, Agraz-Pamplona, Irene, González-Rodríguez, Juan David, Panizo, Nayara, Fraga, Gloria, and Fernández, Loreto

Subjects
POLYCYSTIC kidney disease, YOUNG adults, INTRACRANIAL arterial diseases
Abstract

Background The clinical manifestations of autosomal dominant polycystic kidney disease (ADPKD) usually appear in adulthood, however pediatric series report a high morbidity. The objective of the study was to analyze the clinical characteristics of ADPKD in young adults. Methods Family history, hypertension, albuminuria, estimated glomerular filtration rate (eGFR) and imaging tests were examined in 346 young adults (18–30 years old) out of 2521 patients in the Spanish ADPKD registry (REPQRAD). A literature review searched for reports on hypertension in series with more than 50 young (age <30 years) ADPKD patients. Results The mean age of this young adult cohort was 25.24 (SD 3.72) years. The mean age at diagnosis of hypertension was 21.15 (SD 4.62) years, while in the overall REPQRAD population was aged 37.6 years. The prevalence of hypertension was 28.03% and increased with age (18–24 years, 16.8%; 25–30 years, 36.8%). Although prevalence was lower in women than in men, the age at onset of hypertension (21 years) was similar in both sexes. Mean eGFR was 108 (SD 21) mL/min/1.73 m2, 38.0% had liver cysts and 3.45% of those studied had intracranial aneurysms. In multivariate analyses, hematuria episodes and kidney length were independent predictors of hypertension (area under the curve 0.75). The prevalence of hypertension in 22 pediatric cohorts was 20%–40%, but no literature reports on hypertension in young ADPKD adults were found. Conclusions Young adults present non-negligible ADPKD-related morbidity. This supports the need for a thorough assessment of young adults at risk of ADPKD that allows early diagnosis and treatment of hypertension. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Thrombotic microangiopathy in patients with malignant hypertension

Author

Cavero, Teresa, primary, Auñón, Pilar, additional, Caravaca-Fontán, Fernando, additional, Trujillo, Hernando, additional, Arjona, Emi, additional, Morales, Enrique, additional, Guillén, Elena, additional, Blasco, Miquel, additional, Rabasco, Cristina, additional, Espinosa, Mario, additional, Blanco, Marta, additional, Rodríguez-Magariños, Catuxa, additional, Cao, Mercedes, additional, Ávila, Ana, additional, Huerta, Ana, additional, Rubio, Esther, additional, Cabello, Virginia, additional, Barros, Xoana, additional, Goicoechea de Jorge, Elena, additional, Rodríguez de Córdoba, Santiago, additional, and Praga, Manuel, additional

Published
2022
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49. SARS-CoV-2 Infection Evolution Among Nephrologists During the Pandemic: Clinical Features and Impact of Vaccination

Author

Quiroga, Borja, primary, Ortiz, Alberto, additional, Sánchez-Álvarez, Emilio, additional, Goicoechea, Marian, additional, de Sequera, Patricia, additional, de Arriba, Gabriel, additional, Quiroga, Borja, additional, Blasco, Miquel, additional, Fernández Fresnedo, Gema, additional, Soriano, Sagrario, additional, Pérez Contreras, Francisco Javier, additional, Mazuecos, Auxiliadora, additional, Gorostidi, Manuel, additional, Soler, María José, additional, and Rodríguez Portillo, Mariano, additional

Published
2022
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