71 results on '"Bianca Kramer"'
Search Results
2. Advancing open access in the Netherlands after 2020: from quantity to quality
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Jeroen Bosman, Hans de Jonge, Bianca Kramer, and Jeroen Sondervan
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open access ,the netherlands ,quality of open access ,policies ,universities ,funding organisations ,Bibliography. Library science. Information resources - Abstract
The purpose of this article is to explore options to further open access in the Netherlands from 2021. Its premise is that there is a need to look at the qualitative aspects of open access, alongside quantitative ones. The article first takes stock of progress that has been made. Next, we suggest broadening the agenda by involving more types of actors and other scholarly formats (like books, chapters, proceedings, preprints and textbooks). At the same time we suggest deepening the open access agenda by including several open access dimensions: immediacy, diamond open access, open metadata, open peer review and open licences. To facilitate discussion, a framework is proposed that allows specifying these actions by the a) aspects of open access they address (what is made open access, how, when and where it is made open access, and copyright and rights retention), b) the actors that play a role (government, research institutions, funders) and c) the various levels at which these actions can be taken: state as goal, set as policy, legalize and promote, recognize and reward, finance, support with infrastructure. A template is provided to ease the use of the framework.
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- 2021
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3. An open toolkit for tracking open science partnership implementation and impact [version 2; peer review: 2 approved]
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E. Richard Gold, Sarah E. Ali-Khan, Liz Allen, Lluis Ballell, Manoel Barral-Netto, David Carr, Damien Chalaud, Simon Chaplin, Matthew S. Clancy, Patricia Clarke, Robert Cook-Deegan, A. P. Dinsmore, Megan Doerr, Lisa Federer, Steven A. Hill, Neil Jacobs, Antoine Jean, Osmat Azzam Jefferson, Chonnettia Jones, Linda J. Kahl, Thomas M. Kariuki, Sophie N. Kassel, Robert Kiley, Elizabeth Robboy Kittrie, Bianca Kramer, Wen Hwa Lee, Emily MacDonald, Lara M. Mangravite, Elizabeth Marincola, Daniel Mietchen, Jennifer C. Molloy, Mark Namchuk, Brian A. Nosek, Sébastien Paquet, Claude Pirmez, Annabel Seyller, Malcolm Skingle, S. Nicole Spadotto, Sophie Staniszewska, and Mike Thelwall
- Subjects
Medicine - Abstract
Serious concerns about the way research is organized collectively are increasingly being raised. They include the escalating costs of research and lower research productivity, low public trust in researchers to report the truth, lack of diversity, poor community engagement, ethical concerns over research practices, and irreproducibility. Open science (OS) collaborations comprise of a subset of open practices including open access publication, open data sharing and the absence of restrictive intellectual property rights with which institutions, firms, governments and communities are experimenting in order to overcome these concerns. We gathered two groups of international representatives from a large variety of stakeholders to construct a toolkit to guide and facilitate data collection about OS and non-OS collaborations. Ultimately, the toolkit will be used to assess and study the impact of OS collaborations on research and innovation. The toolkit contains the following four elements: 1) an annual report form of quantitative data to be completed by OS partnership administrators; 2) a series of semi-structured interview guides of stakeholders; 3) a survey form of participants in OS collaborations; and 4) a set of other quantitative measures best collected by other organizations, such as research foundations and governmental or intergovernmental agencies. We opened our toolkit to community comment and input. We present the resulting toolkit for use by government and philanthropic grantors, institutions, researchers and community organizations with the aim of measuring the implementation and impact of OS partnership across these organizations. We invite these and other stakeholders to not only measure, but to share the resulting data so that social scientists and policy makers can analyse the data across projects.
- Published
- 2019
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4. Defining the Scholarly Commons - Reimagining Research Communication. Report of Force11 SCWG Workshop, Madrid, Spain, February 25-27, 2016
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Bianca Kramer, Jeroen Bosman, Marcin Ignac, Christina Kral, Tellervo Kalleinen, Pekko Koskinen, Ian Bruno, Amy Buckland, Sarah Callaghan, Robin Champieux, Chris Chapman, Stephanie Hagstrom, MaryAnn Martone, Fiona Murphy, and Daniel O'Donnell
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scholarly communication ,research communication ,Science - Published
- 2016
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5. Are Funder Open Access Platforms a Good Idea?
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Tony Ross-Hellauer, Birgit Schmidt, and Bianca Kramer
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History of scholarship and learning. The humanities ,AZ20-999 ,Social Sciences - Abstract
As open access (OA) to publications continues to gather momentum, we should continuously question whether it is moving in the right direction. A novel intervention in this space is the creation of OA publishing platforms commissioned by funding organizations. Examples include those of the Wellcome Trust and the Gates Foundation, as well as recently announced initiatives from public funders like the European Commission and the Irish Health Research Board. As the number of such platforms increases, it becomes urgently necessary to assess in which ways, for better or worse, this emergent phenomenon complements or disrupts the scholarly communications landscape. This article examines ethical, organizational, and economic strengths and weaknesses of such platforms, as well as usage and uptake to date, to scope the opportunities and threats presented by funder OA platforms in the ongoing transition to OA. The article is broadly supportive of the aims and current implementations of such platforms, finding them a novel intervention which stands to help increase OA uptake, control costs of OA, lower administrative burden on researchers, and demonstrate funders’ commitment to fostering open practices. However, the article identifies key areas of concern about the potential for unintended consequences, including the appearance of conflicts of interest, difficulties of scale, potential lock-in, and issues of the branding of research. The article ends with key recommendations for future consideration which include a focus on open scholarly infrastructure.
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- 2018
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6. Thinking the unthinkable – doing away with the library catalogue
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Simone Kortekaas and Bianca Kramer
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Bibliography. Library science. Information resources - Abstract
At Utrecht University we strongly believe that academic libraries have lost their role in the discovery of scientific information and should focus on delivery instead. Without your own discovery tool you might feel stark naked. However, we have to admit that others can do a better job on discovery, so don’t spend too much time on this. Make a priority of your delivery task and rethink the way you can provide value for your users.
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- 2014
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7. Ten Hot Topics around Scholarly Publishing
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Jonathan P. Tennant, Harry Crane, Tom Crick, Jacinto Davila, Asura Enkhbayar, Johanna Havemann, Bianca Kramer, Ryan Martin, Paola Masuzzo, Andy Nobes, Curt Rice, Bárbara Rivera-López, Tony Ross-Hellauer, Susanne Sattler, Paul D. Thacker, and Marc Vanholsbeeck
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peer review ,copyright ,open access ,open science ,scholarly communication ,web of science ,Scopus ,impact factor ,research evaluation ,Communication. Mass media ,P87-96 ,Information resources (General) ,ZA3040-5185 - Abstract
The changing world of scholarly communication and the emerging new wave of ‘Open Science’ or ‘Open Research’ has brought to light a number of controversial and hotly debated topics. Evidence-based rational debate is regularly drowned out by misinformed or exaggerated rhetoric, which does not benefit the evolving system of scholarly communication. This article aims to provide a baseline evidence framework for ten of the most contested topics, in order to help frame and move forward discussions, practices, and policies. We address issues around preprints and scooping, the practice of copyright transfer, the function of peer review, predatory publishers, and the legitimacy of ‘global’ databases. These arguments and data will be a powerful tool against misinformation across wider academic research, policy and practice, and will inform changes within the rapidly evolving scholarly publishing system.
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- 2019
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8. Innovations in scholarly communication - global survey on research tool usage [version 1; referees: 2 approved]
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Bianca Kramer and Jeroen Bosman
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Public Engagement ,Publishing & Peer Review ,Science & Medical Education ,Medicine ,Science - Abstract
Many new websites and online tools have come into existence to support scholarly communication in all phases of the research workflow. To what extent researchers are using these and more traditional tools has been largely unknown. This 2015-2016 survey aimed to fill that gap. Its results may help decision making by stakeholders supporting researchers and may also help researchers wishing to reflect on their own online workflows. In addition, information on tools usage can inform studies of changing research workflows. The online survey employed an open, non-probability sample. A largely self-selected group of 20663 researchers, librarians, editors, publishers and other groups involved in research took the survey, which was available in seven languages. The survey was open from May 10, 2015 to February 10, 2016. It captured information on tool usage for 17 research activities, stance towards open access and open science, and expectations of the most important development in scholarly communication. Respondents’ demographics included research roles, country of affiliation, research discipline and year of first publication.
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- 2016
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9. An open source machine learning framework for efficient and transparent systematic reviews.
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Rens van de Schoot, Jonathan de Bruin, Raoul Schram, Parisa Zahedi, Jan de Boer, Felix Weijdema, Bianca Kramer, Martijn Huijts, Maarten Hoogerwerf, Gerbrich Ferdinands, Albert Harkema, Joukje Willemsen, Yongchao Ma, Qixiang Fang, Sybren Hindriks, Lars Tummers, and Daniel L. Oberski
- Published
- 2021
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10. Open metadata - where do we stand? (Keynote).
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Bianca Kramer
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- 2021
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11. ASReview: Open Source Software for Efficient and Transparent Active Learning for Systematic Reviews.
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Rens van de Schoot, Jonathan de Bruin, Raoul Schram, Parisa Zahedi, Jan de Boer, Felix Weijdema, Bianca Kramer, Martijn Huijts, Maarten Hoogerwerf, Gerbrich Ferdinands, Albert Harkema, Joukje Willemsen, Yongchao Ma, Qixiang Fang, Lars Tummers, and Daniel L. Oberski
- Published
- 2020
12. Developments in Peer Review. Disruptive conversations series: Peer Review under Pressure
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Bianca Kramer
- Abstract
This presentation focuses on the developments in Peer Review, from a historical perspective to challnges associated with the process of peer review today.
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- 2023
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13. Workshop - DIAMAS Project
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Jeroen Bosman and Bianca Kramer
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open access ,institutional publishing ,DIAMAS project - Abstract
In this workshop, participants were briefly informed about the goals and scope of DIAMAS project and the important role of librarians. Then, they hada first try at identifying IPSPs within their own institution.
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- 2022
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14. Crossref metadata for preprints: Discussions and recommendations
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Martyn Rittman, Emily Marchant, Johanna Havemann, Oya Y Rieger, Alainna Therese Wrigley, Alberto Pepe, Alex Mendonça, Benjamin Mudrak, Bianca Kramer, Damian Pattinson, Dasapta Erwin Irawan, Ioana Craciun, Jessica Polka, Johannes Wagner, Michael Markie, Michael Parkin, Michele Avissar-Whiting, Nicole Pfeiffer, Patricia Feeney, Richard Sever, Richard Wynne, Shirley Decker-Lucke, Tony Alves, and Wendy Patterson
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MetaArXiv|Social and Behavioral Sciences|Library and Information Science|Scholarly Communication ,MetaArXiv|Social and Behavioral Sciences ,bepress|Social and Behavioral Sciences|Library and Information Science|Scholarly Communication ,MetaArXiv|Social and Behavioral Sciences|Library and Information Science|Scholarly Publishing ,bepress|Social and Behavioral Sciences ,bepress|Social and Behavioral Sciences|Library and Information Science|Scholarly Publishing ,bepress|Social and Behavioral Sciences|Library and Information Science ,MetaArXiv|Social and Behavioral Sciences|Library and Information Science - Abstract
In 2016, Crossref launched a metadata schema for ‘posted content’ with the aim of better accommodating the metadata needs for preprints, working papers, theses, reports, and related outputs, which are not typically peer-reviewed. In 2021, Crossref formed an Advisory Group (AG) to discuss how the quality of metadata for preprints using this schema could be improved. The group focused on four topics: 1) preprints as an article type (rather than subtype of posted-content); 2) relationships to/from preprints; 3) versioning; and 4) withdrawal/removal of preprints. The recommendations that resulted from the group’s deliberations have been published previously. Here we provide further background to the recommendations and report more details of the discussions.
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- 2022
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15. Availability and completeness of funder metadata in Crossref
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Hans De Jonge and Bianca Kramer
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Open metadata ,Crossref ,Funding information ,General Medicine - Abstract
Research funders spend considerable efforts on collecting information about the outcomes of the research they fund. Publications are amongst important data they collect because these represent direct results of research funding. To help funders track publication output associated with their funding, Crossref initiated the Fundref project in 2013, enabling publishers to deposit funding information using persistent identifiers. Currently, 25% of articles published in 2021 have funder metadata. However, it is hard to assess that figure because it is not known how many articles are the result of funded research and therefore should include funder metadata. In this poster we present the outcomes of a study in which we try to assess the availability and completeness of funding information in Crossref. For this analysis we made use of a subset of publications of which we are certain that they are the result of funding provided by a specific funding agency (the Dutch Research Council NWO) and therefore – in theory – should contain funding information. We also compared our findings with the availability of funding information in the larger (commercial) databases. Only 67% of the 5004 articles in our dataset contain funding information in Crossref, with a subset acknowledging NWO as funder name and/or Funder IDs linked to NWO (53% and 45%, respectively). Web of Science (WoS), Scopus and Dimensions are all able to infer additional funding information from funding statements in the full text of the articles. Funding information in Lens largely corresponds to that in Crossref, with some additional funding information likely taken from PubMed. We observe interesting differences between publishers in the coverage and completeness of funding metadata in Crossref compared to proprietary databases, highlighting the need for publishers to step up their efforts to collect this data and submit to Crossref. The open unrestricted availability of structured, machine readable information about the funding of research is important for multiple reasons. Important progress has been made in recent years to promote the open availability of metadata of the scholarly record. Our research shows that the open availability of funding information, while increasing, also needs improvement.
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- 2022
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16. Crossref Annual Meeting LIVE22 presentation
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Javier Arias, Ed Pentz, Edilson Damasio, Isaac Farley, Vanessa Fairhurst, Lettie Conrad, Hans De Jonge, and Bianca Kramer
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The Crossref annual meeting and board election took place on October 26, 2022, online. The slide deck includes strategic updates from our team, guest speakers, as well as the results of the board election.
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- 2022
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17. Preprints and open preprint review: a workshop on innovations in scholarly publishing
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Bianca Kramer, Ludo Waltman, Jeroen Sondervan, and Jeroen Bosman
- Abstract
Researchers, librarians, policy makers, and practitioners often complain about the scholarly publishing system, but the system also offers exciting opportunities to contribute to innovations in the way academic findings are disseminated and evaluated. At the Dutch Open Science Festival, which took place at the Vrije Universiteit Amsterdam on September 1st 2022, we organized one of the ???community-led??? workshops to discuss some of these developments, focusing on preprints and open preprint review.
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- 2022
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18. Presentation: The availability and completeness of open funder metadata - Case study for publications funded by the Dutch Research Council
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Bianca Kramer and de Jonge, Hans
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Lens ,Funding data ,Open metadata ,Crossref ,Scopus ,Web of Science ,Dimensions - Abstract
Presentation for: Workshop on Open Citations and Open Scholarly Metadata 2022 (online), October 5 2022 Abstract: Research funders spend considerable efforts collecting information on outcomes of the research they fund. To help funders track publication output associated with their funding, Crossref initiated FundRef in 2013, enabling publishers to register funding information using persistent identifiers. However, it is hard to assess the coverage of funder metadata because it is unknown how many articles are the result of funded research and therefore should include funder metadata. We looked at 5,004 publications reported by researchers to be the result of funding by a specific funding agency: the Dutch Research Council NWO. Only 67% of these articles contain funding information in Crossref, with a subset acknowledging NWO as funder name and/or Funder IDs linked to NWO (53% and 45%, respectively). Web of Science (WoS), Scopus and Dimensions are all able to infer additional funding information from funding statements in the full text of the articles. Funding information in Lens largely corresponds to that in Crossref, with some additional funding information likely taken from PubMed. We observe interesting differences between publishers in the coverage and completeness of funding metadata in Crossref compared to proprietary databases, highlighting potential to increase the quality of open metadata on funding., The recording of this presentation is also available on YouTube: https://youtu.be/PWCvd8XaWpk
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- 2022
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19. AI-aided Systematic Review to Create a Database with Potentially Relevant Papers on Depression, Anxiety, and Addiction
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Marlies Brouwer, Laura Hofstee, Sofie Arsenia Gabriëlla Eleonora van den Brand, Jelle Teijema, Gerbrich Ferdinands, Jan de Boer, Felix Weijdema, Bianca Kramer, Reinout Wiers, Claudi Bockting, Jonathan de Bruin, and Rens van de Schoot
- Abstract
It is of utmost importance to provide an overview and strength of evidence of predictive factors and to investigate the current state of affairs on evidence for all published and hypothesized factors that contribute to the onset, relapse, and maintenance of anxiety-, substance use-, and depressive disorders. Thousands of such articles have been published on potential factors of CMDs, yet a clear overview of all preceding factors and interaction between factors is missing. Therefore, the main aim of the current project was to create a database with potentially relevant papers obtained via a systematic. The current paper describes every step of the process of constructing the database, from search query to database. After a broad search and cleaning of the data, we used active learning using a shallow classifier and labeled the first set of papers. Then, we applied a second screening phase in which we switched to a different active learning model (i.e., a neural net) to identify difficult-to-find papers due to concept ambiguity. In the third round of screening, we checked for incorrectly included/excluded papers in a quality assessment procedure resulting in the final database. All scripts, data files, and output files of the software are available via Zenodo (for Github code), the Open Science Framework (for protocols, output), and DANS (for the datasets) and are referred to in the specific sections, thereby making the project fully reproducible.
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- 2022
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20. Publication Strategies and Open Science
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Bianca Kramer, Jeroen Bosman, Ebuka Ezeike, and Jo Havemann
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- 2022
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21. Author response for 'The availability and completeness of open funder metadata: Case study for publications funded by the Dutch Research Council'
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null Bianca Kramer and null Hans de Jonge
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- 2022
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22. Bianca Kramer is Keeping Tabs on Open Research
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Bianca Kramer
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Bianca Kramer has been scholarly communication/open science librarian at Utrecht University Library for 15 years, and recently moved to an independent consulting/research analyst role as Sesame Open Science, with a focus on open science, open metadata and open infrastructure. Being encouraged to keep ???open tabs???, has been an interesting experience - turning something that???s usually guilt-inducing (???I really should be reading this???!???) into something that at least feels productive (???Oh, I could u
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- 2022
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23. Preprint metadata recommendations
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Martyn Rittman, Alainna Wrigley, Alberto Pepe, Alex Mendonça, Benjamin Mudrak, Bianca Kramer, Dasapta Erwin Irawan, Emily Marchant, Ioana Craciun, Jeffrey Beck, Jessica Polka, Johanna Havemann, Johannes Wagner, Michael Markie, Michael Parkin, Michele Avissar-Whiting, Nicole Pfeiffer, Richard Sever, Richard Wynne, Shirley Decker-Lucke, Anthony Alves, Wendy Patterson, Patricia Feeney, and Damian Pattinson
- Abstract
The Crossref Preprint Advisory Group (AG) was formed in June 2021 to discuss metadata issues related to preprints. It has the following aims...
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- 2022
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24. Language Diversity in Scholarly Publishing
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Cameron Neylon and Bianca Kramer
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Data Processing and production: Jamie Diprose Cross-posted from the COKI blog. There is a lot of lip service paid to the idea of diversity in scholarly publishing and often diversity of language is used as an example. The Helsinki Initiative is one example of an explicit call for multilingualism and the Jussieu Call for bibliodiversity, while it does not explicitly mention language, is an implicit criticism of anglo-centric publishing. The UNESCO Open Science Recommendation states that ???ope
- Published
- 2022
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25. Emil und die Detektive - Kästners meistverfilmtes Kinderbuch: Eine Analyse der deutschen Literaturadaptionen
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Bianca Kramer
- Published
- 2014
26. An Open Knowledge Base for the Netherlands: Report of a Community Workshop
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Cameron Neylon, Magchiel Bijsterbosch, Alastair Dunning, Bianca Kramer, Sarah de Rijcke, Clifford Tatum, and Ludo Waltman
- Abstract
The concept of developing a national Open Knowledge Base for the Netherlands (NL-OKB) has been proposed in response to the strategic needs of the research community in the Netherlands. In parallel with the work of the Dutch Taskforce on Responsible Management of Research Information and Dataaddressing these opportunities and the preparation of a feasibility study by Dialogic, interested stakeholders were convened with the goal of identifying expert and user-community interests in and need for an NL-OKB. The goal in convening a workshop was: 1. To gather evidence on the feasibility of an NL-OKB 2. To test the community interest and appetite for developing an NL-OKB 3. To identify a practical pathway forward towards startup and implementation of an NL-OKB Over two days, 19-20 November 2020, 35 participants representing national and international organisations met in a virtual workshop. This included representatives of VSNU, NWO, NFU, SURF, DANS, CWTS and a range of Netherlands institutions alongside international stakeholders such as Crossref, ORCID, OpenAIRE, DataCite, SPARC North America, Jisc, UKRI and others. There was strong support for an NL-OKB amongst the assembled group. The group as a whole was strongly in favour of the development of an NL-OKB run on behalf of and controlled by the academic community. Of those present, virtually all indicated they had a direct stake and interest in supporting the development of an NL-OKB. International participants were also keen to see efforts in the Netherlands succeed as an exemplar to be drawn upon. The assembled group reached a series of consensus conclusions, that taken together provide the beginnings of a roadmap for further development. This report was prepared by the workshop conveners: Cameron Neylon (Curtin University), Magchiel Bijsterbosch (SURF), Alastair Dunning (TU Delft), Bianca Kramer (Utrecht University), Sarah de Rijcke (Leiden University), Clifford Tatum (SURF; Leiden University) and Ludo Waltman (Leiden University).Thereport may be re-used under a Creative Common Attribution v4 License.
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- 2021
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27. Publisher Correction: Bayesian statistics and modelling
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Bianca Kramer, Christopher Yau, Marina Vannucci, Joukje Willemsen, Ruth King, Sarah Depaoli, Andrew Gelman, Kaspar Märtens, Mahlet G. Tadesse, Rens van de Schoot, and Duco Veen
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Bayesian statistics ,General Medicine ,Data mining ,computer.software_genre ,computer ,General Biochemistry, Genetics and Molecular Biology - Published
- 2021
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28. Bayesian statistics and modelling
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Rens van de Schoot, Sarah Depaoli, Christopher Yau, Bianca Kramer, Ruth King, Marina Vannucci, Mahlet G. Tadesse, Andrew Gelman, Joukje Willemsen, Kaspar Märtens, and Duco Veen
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business.industry ,Computer science ,Bayesian probability ,Posterior probability ,Inference ,Statistical model ,General Medicine ,Machine learning ,computer.software_genre ,General Biochemistry, Genetics and Molecular Biology ,Statistics::Computation ,Bayesian statistics ,Bayes' theorem ,ComputingMethodologies_PATTERNRECOGNITION ,Prior probability ,Taverne ,Artificial intelligence ,business ,Likelihood function ,computer - Abstract
Bayesian statistics is an approach to data analysis based on Bayes’ theorem, where available knowledge about parameters in a statistical model is updated with the information in observed data. The background knowledge is expressed as a prior distribution and combined with observational data in the form of a likelihood function to determine the posterior distribution. The posterior can also be used for making predictions about future events. This Primer describes the stages involved in Bayesian analysis, from specifying the prior and data models to deriving inference, model checking and refinement. We discuss the importance of prior and posterior predictive checking, selecting a proper technique for sampling from a posterior distribution, variational inference and variable selection. Examples of successful applications of Bayesian analysis across various research fields are provided, including in social sciences, ecology, genetics, medicine and more. We propose strategies for reproducibility and reporting standards, outlining an updated WAMBS (when to Worry and how to Avoid the Misuse of Bayesian Statistics) checklist. Finally, we outline the impact of Bayesian analysis on artificial intelligence, a major goal in the next decade. This Primer on Bayesian statistics summarizes the most important aspects of determining prior distributions, likelihood functions and posterior distributions, in addition to discussing different applications of the method across disciplines.
- Published
- 2021
29. Summer school Open science and scholarship 2019 - Utrecht University
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Jeroen Bosman and Bianca Kramer
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summer school ,open science training ,open science ,ComputingMilieux_COMPUTERSANDEDUCATION ,open science skills ,utrecht university ,open research ,open scholarship - Abstract
From August 26th-30th 2019, Utrecht University hosted the 3rd edition of the summer school course ‘Open Science and Scholarship – changing your research workflow’ The one-week, full-time course is aimed at researchers of all disciplines and career levels, interested in learning how to make open science integral part of their own research practice. The 2019 course was aimed specifically at researchers at Utrecht University, but the materials can be re-used and modified by anyone. We use participants’ own workflow and outputs as starting point (from getting funding to doing your research in the open, making your research more visible and being rewarded for openness). The course alternates between theory, discussing that theory and immediately putting that theory into practice. The course touches on open science goals and funding, open access, open data, open peer review, assessment, reproducibility, doing outreach and more. At the end of the course, participants have a toolbox of practical approaches making research more open and will have started applying some of them. They will also have a better understanding of the benefits of doing so, and how to deal with existing barriers towards open science and scholarship. The course also enables participants to continue the conversation about open science at their department, as all course materials are made available for reuse., Slides provided as pdf and pptx, syllabus (with programme and materials) provided as pdf; syllabus is also available online at https://tinyurl.com/sumsopenscience2019
- Published
- 2020
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30. Decision letter: Evaluating the impact of open access policies on research institutions
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Bianca Kramer
- Published
- 2020
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31. Ten Hot Topics around Scholarly Publishing
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Marc Vanholsbeeck, Paul D. Thacker, Ryan Martin, Harry Crane, Curt Rice, Andy Nobes, Tony Ross-Hellauer, Susanne Sattler, Bárbara Rivera-López, Asura Enkhbayar, Johanna Havemann, Paola Masuzzo, Tom Crick, Jonathan P. Tennant, Jacinto Dávila, and Bianca Kramer
- Subjects
scholarly communication ,media_common.quotation_subject ,Library and Information Sciences ,050905 science studies ,Scholarly communication ,lcsh:Communication. Mass media ,research evaluation ,Open research ,Political science ,open science ,Media Technology ,Scopus ,Information et communication ,Misinformation ,Business and International Management ,impact factor ,Function (engineering) ,Legitimacy ,media_common ,open access ,Impact factor ,business.industry ,Communication ,copyright ,lcsh:Information resources (General) ,05 social sciences ,scholarly publication ,Public relations ,science communication ,lcsh:P87-96 ,Computer Science Applications ,Publishing ,Rhetoric ,web of science ,0509 other social sciences ,050904 information & library sciences ,business ,lcsh:ZA3040-5185 - Abstract
The changing world of scholarly communication and the emerging new wave of ‘Open Science’ or ‘Open Research’ has brought to light a number of controversial and hotly debated topics. Evidence-based rational debate is regularly drowned out by misinformed or exaggerated rhetoric, which does not benefit the evolving system of scholarly communication. This article aims to provide a baseline evidence framework for ten of the most contested topics, in order to help frame and move forward discussions, practices, and policies. We address issues around preprints and scooping, the practice of copyright transfer, the function of peer review, predatory publishers, and the legitimacy of ‘global’ databases. These arguments and data will be a powerful tool against misinformation across wider academic research, policy and practice, and will inform changes within the rapidly evolving scholarly publishing system., info:eu-repo/semantics/published
- Published
- 2019
32. Ten myths around open scholarly publishing
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Paola Masuzzo, Ryan Martin, Jacinto Dávila, Bárbara R. López, Bianca Kramer, Asura Enkhbayar, Johanna Havemann, Tony Ross-Hellauer, Harry Crane, Paul D. Thacker, Susanne Sattler, Jonathan P. Tennant, Marc Vanholsbeeck, Andy Nobes, Tom Crick, and Curt Rice
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0303 health sciences ,Open science ,Web of science ,business.industry ,05 social sciences ,Scopus ,Library science ,Mythology ,Scholarly communication ,03 medical and health sciences ,Publishing ,Political science ,0509 other social sciences ,050904 information & library sciences ,business ,030304 developmental biology - Abstract
The changing world of scholarly communication and the emergence of ‘Open Science’ or ‘Open Research’ has brought to light a number of controversial and hotly-debated topics. Yet, evidence-based rational debate is regularly drowned out by misinformed or exaggerated rhetoric, which does not benefit the evolving system of scholarly communication. The aim of this article is to provide a baseline evidence framework for ten of the most contested topics, in order to help frame and move forward discussions, practices and policies. We address preprints and scooping, the practice of copyright transfer, the function of peer review, and the legitimacy of ‘global’ databases. The presented facts and data will be a powerful tool against misinformation across wider academic research, policy and practice, and may be used to inform changes within the rapidly evolving scholarly publishing system.
- Published
- 2019
- Full Text
- View/download PDF
33. An open toolkit for tracking open science partnership implementation and impact
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Megan Doerr, Daniel Mietchen, Sophie Staniszewska, Brian A. Nosek, Jennifer C. Molloy, Claude Pirmez, Mark N. Namchuk, Lara M. Mangravite, Thomas M. Kariuki, Matthew S. Clancy, Manoel Barral-Netto, Lisa Federer, Damien Chalaud, Sarah E. Ali-Khan, Linda J. Kahl, S. Nicole Spadotto, Mike Thelwall, Elizabeth Marincola, Wen Hwa Lee, Elizabeth Robboy Kittrie, Chonnettia Jones, Steven A. Hill, David Carr, Sophie N. Kassel, Patricia Clarke, Robert Robert Cook-Deegan, Antoine Jean, Sébastien Paquet, Robert Kiley, Malcolm Skingle, Emily MacDonald, Annabel Seyller, Adam Dinsmore, Osmat Azzam Jefferson, Simon Chaplin, Lluis Ballell, Bianca Kramer, Liz Allen, Neil Jacobs, E. Richard Gold, Gold, E Richard [0000-0002-3789-9238], Allen, Liz [0000-0002-9298-3168], Ballell, Lluis [0000-0002-3029-1860], Barral-Netto, Manoel [0000-0002-5823-7903], Chaplin, Simon [0000-0002-2705-6480], Clancy, Matthew S [0000-0001-7177-1038], Dinsmore, AP [0000-0002-3314-7944], Jones, Chonnettia [0000-0003-3430-8110], Kiley, Robert [0000-0003-4733-2558], Mietchen, Daniel [0000-0001-9488-1870], Pirmez, Claude [0000-0002-7443-0455], Seyller, Annabel [0000-0002-2168-3125], Staniszewska, Sophie [0000-0002-7723-9074], and Apollo - University of Cambridge Repository
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0301 basic medicine ,Open science ,Community organization ,partnership ,Medicine (miscellaneous) ,toolkit ,Intellectual property ,Q1 ,Biochemistry, Genetics and Molecular Biology (miscellaneous) ,03 medical and health sciences ,0302 clinical medicine ,Immunology and Microbiology (miscellaneous) ,Political science ,implementation ,Government ,Community engagement ,business.industry ,Health Policy ,indicator ,Public Health, Environmental and Occupational Health ,Articles ,Public relations ,intellectual property ,innovation ,Open data ,030104 developmental biology ,General partnership ,Public trust ,impact ,business ,030217 neurology & neurosurgery ,performance ,Research Article ,policy - Abstract
Serious concerns about the way research is organized collectively are increasingly being raised. They include the escalating costs of research and lower research productivity, low public trust in researchers to report the truth, lack of diversity, poor community engagement, ethical concerns over research practices, and irreproducibility. Open science (OS) collaborations comprise of a subset of open practices including open access publication, open data sharing and the absence of restrictive intellectual property rights with which institutions, firms, governments and communities are experimenting in order to overcome these concerns. We gathered two groups of international representatives from a large variety of stakeholders to construct a toolkit to guide and facilitate data collection about OS and non-OS collaborations. Ultimately, the toolkit will be used to assess and study the impact of OS collaborations on research and innovation. The toolkit contains the following four elements: 1) an annual report form of quantitative data to be completed by OS partnership administrators; 2) a series of semi-structured interview guides of stakeholders; 3) a survey form of participants in OS collaborations; and 4) a set of other quantitative measures best collected by other organizations, such as research foundations and governmental or intergovernmental agencies. We opened our toolkit to community comment and input. We present the resulting toolkit for use by government and philanthropic grantors, institutions, researchers and community organizations with the aim of measuring the implementation and impact of OS partnership across these organizations. We invite these and other stakeholders to not only measure, but to share the resulting data so that social scientists and policy makers can analyse the data across projects.
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- 2019
34. Open Science Training Handbook
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Sonja Bezjak, April Clyburne-Sherin, Philipp Conzett, Pedro Fernandes, Edit Görögh, Kerstin Helbig, Bianca Kramer, Ignasi Labastida, Kyle Niemeyer, Fotis Psomopoulos, Tony Ross-Hellauer, René Schneider, Jon Tennant, Ellen Verbakel, Helene Brinken, and Lambert Heller
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Open Science ,4. Education ,05 social sciences ,Vocational training ,050301 education ,Training ,050109 social psychology ,0501 psychology and cognitive sciences ,Translational skills ,0503 education - Abstract
For a readable version of the book, please visit https://book.fosteropenscience.eu A group of fourteen authors came together in February 2018 at the TIB (German National Library of Science and Technology) in Hannover to create an open, living handbook on Open Science training. High-quality trainings are fundamental when aiming at a cultural change towards the implementation of Open Science principles. Teaching resources provide great support for Open Science instructors and trainers. The Open Science training handbook will be a key resource and a first step towards developing Open Access and Open Science curricula and andragogies. Supporting and connecting an emerging Open Science community that wishes to pass on their knowledge as multipliers, the handbook will enrich training activities and unlock the community’s full potential. In this first release of the Open Science Training Handbook, some initial feedback from the community is already included.
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- 2018
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35. Characterizing physicians’ information needs at the point of care
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Lauren A. Maggio, Bianca Kramer, Edith ter Braak, Laura Moorhead, Keith A Posley, Olle ten Cate, Feikje van Stiphout, Bridget C. O’Brien, and David M. Irby
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Medical education ,Evidence-based medicine ,medicine.medical_specialty ,Personal learning ,business.industry ,Information storage and retrieval ,Information needs ,Education ,Variety (cybernetics) ,Identification (information) ,Qualitative research ,Family medicine ,Medicine ,Original Article ,Thematic analysis ,business ,Internal medicine ,Point of care - Abstract
Physicians have many information needs that arise at the point of care yet go unmet for a variety of reasons, including uncertainty about which information resources to select. In this study, we aimed to identify the various types of physician information needs and how these needs relate to physicians’ use of the database PubMed and the evidence summary tool UpToDate. We conducted semi-structured interviews with physicians (Stanford University, United States; n = 13; and University Medical Center Utrecht, the Netherlands; n = 9), eliciting participants’ descriptions of their information needs and related use of PubMed and/or UpToDate. Using thematic analysis, we identified six information needs: refreshing, confirming, logistics, teaching, idea generating and personal learning. Participants from both institutions similarly described their information needs and selection of resources. The identification of these six information needs and their relation to PubMed and UpToDate expands upon previously identified physician information needs and may be useful to medical educators designing evidence-based practice training for physicians.
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- 2014
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36. Searching the Library catalogue through Twitter
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Bianca Kramer
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- 2014
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37. An open toolkit for tracking open science partnership implementation and impact
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Lara M. Mangravite, Elizabeth Robboy Kittrie, Linda J. Kahl, David Carr, Mike Thelwall, Elizabeth Marincola, Steven A. Hill, Antoine Jean, Chonnettia Jones, Patricia Clarke, S. Nicole Spadotto, Múltipla ver em Notas, Jennifer C. Molloy, Claude Pirmez, Lisa Federer, Robert Cook-Deegan, Damien Chalaud, Thomas M. Kariuki, Wen Hwa Lee, Bianca Kramer, Lluis Ballell, Sophie Staniszewska, Liz Allen, Robert Kiley, Mark N. Namchuk, Sophie N. Kassel, Brian A. Nosek, Sébastien Paquet, Annabel Seyller, Adam Dinsmore, Matthew S. Clancy, Neil Jacobs, Malcolm Skingle, E. Richard Gold, Emily MacDonald, Simon Chaplin, Osmat Azzam Jefferson, Megan Doerr, Daniel Mietchen, Sarah E. Ali-Khan, and Manoel Barral Netto
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0301 basic medicine ,Economic research ,National library ,Health Policy ,Public Health, Environmental and Occupational Health ,Medical school ,Medicine (miscellaneous) ,Library science ,Biochemistry, Genetics and Molecular Biology (miscellaneous) ,3. Good health ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Immunology and Microbiology (miscellaneous) ,General partnership ,Tracking (education) ,030217 neurology & neurosurgery - Abstract
Barral Neto, Manoel. Fundacao Oswaldo Cruz. Instituto Goncalo Moniz. Salvador, BA, Brasil. “Documento produzido em parceria ou por autor vinculado a Fiocruz, mas nao consta a informacao no documento”. Centre for Intellectual Property and Policy (CIPP), Faculty of Law, McGill University, Montreal, QC, H3A 1W9, Canada Department of Human Genetics, Faculty of Medicine, McGill University, Montreal, QC, H3A 0C7, Canada Tanenbaum Open Science Institute (TOSI), Montreal Neurological Institute and Hospital, Montreal, QC, H3A 2B4, Canada F1000, London, W1T 4LB, UK Diseases of the Developing World, Global Health R&D, GlaxoSmithKline, Madrid, Spain Fundacao Oswaldo Cruz - Fiocruz, Rio de Janeiro, RJ, 21040-900, Brazil Wellcome Trust, London, NW1 2BE, UK Montreal Neurological Institute and Hospital, Montreal, QC, H3A 2B4, Canada US Department of Agriculture Economic Research Service, Washington, DC, 20024, USA Health Research Board, Dublin, D02 H638, Ireland Arizona State University, Washington, DC, 20006, USA Sage Bionetworks, Seattle, WA, 98121, USA US National Library of Medicine, Bethesda, MD, 20894, USA Research England, UK Research and Innovation, Bristol, BS34 8SR, UK Jisc, Bristol, BS2 0JA, UK Queensland University of Technology, Brisbane, QLD, 4000, Australia The Lens, Canberra, ACT, 2601, Australia African Academy of Sciences, Karen, Nairobi, 00502, Kenya Utrecht University Library, Utrecht, CX, 3584, The Netherlands Structural Genomics Consortium (SGC), University of Oxford, Oxford, OX3 7DQ, UK Data Science Institute, University of Virginia, Charlottesville, VA, 22904, USA University of Cambridge, Cambridge, CB2 3EA, UK Alkermes, Waltham, MA, 02451, USA Department of Psychology, University of Virginia, Charlottesville, VA, 22904-4400, USA Center for Open Science, Charlottesville, VA, 22903-5083, USA Element AI, Montreal, QC, H2W 2R2, Canada GlaxoSmithKline, Stevenage, Herts, SG1 2NY, UK Warwick Research in Nursing, University of Warwick Warwick Research in Nursing, University of Warwick Medical School, Coventry, CV4 7AL, UK University of Wolverhampton, Wolverhampton, WV1 1LY, UK
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- 2019
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38. Clinical manifestations of intermediate allele carriers in Huntington disease
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Cubo E., Ramos-Arroyo M. A., Martinez-Horta S., Martinez-Descalls A., Calvo S., Gil-Polo CAnne-Catherine Bachoud-Lévi, Anna Rita Bentivoglio, Ida Biunno, Raphael M Bonelli, Jean-Marc Burgunder, Stephen B Dunnett, Joaquim J Ferreira, Olivia J Handley, Arvid Heiberg, Torsten Illmann, G Bernhard Landwehrmeyer, Jamie Levey, Maria Ramos-Arroyo, Jørgen E Nielsen, Susana Pro Koivisto, Markku Päivärinta, Raymund A C Roos, Ana Rojo Sebastián, Sarah J Tabrizi, Wim Vandenberghe, Christine Verellen-Dumoulin, Tereza Uhrova, Jan Wahlström, Jacek Zaremba, Verena Baake, Katrin Barth, Adrien Come, Leonor Correia Guedes, Ana Maria Finisterra, Monica Bascuñana Garde, Reineke Bos, Sabrina Betz, Jenny Callaghan, Selene Capodarca, Sébastien Charpentier, Wildson Vieira da Silva, Martina Di Renzo, Daniel Ecker, Ruth Fullam, Camille Genoves, Mette Gilling, Carina Hvalstedt, Christine Held, Andrea Horta-Barba, Kerstin Koppers, Claudia Lamanna, Matilde Laurà, Asunción Martínez Descals, Saul Martinez-Horta, Tiago Mestre, Sara Minster, Daniela Monza, Lisanne Mütze, Martin Oehmen, Helene Padieu, Laurent Paterski, Nadia Peppa, Beate Rindal, Dawn Rogers, Niini Røren, Pavla Šašinková, Yuri Seliverstov, Catherine Taylor, Erika Timewell, Jenny Townhill, Patricia Trigo Cubillo, Marleen R van Walsem, Marie-Noelle Witjes-Ané, Grzegorz Witkowski, Abigail Wright, Elizaveta Yudina, Daniel Zielonka, Eugeniusz Zielonka, Paola Zinzi, Cécile Minet, Pascale Ribaï, Dominique Van Paemel, Lena Hjermind, Oda Jacobsen, Suzanne Lindquist, Jørgen Nielsen, Lisbeth Regeur, Jette Stockholm, Ida Unmack Larsen, Christina Vangsted-Hansen, Tua Vinther-Jensen, Pia Eklund, Heli Hiivola, Hannele Hypponen, Kirsti Martikainen, Katri Tuuha, Philippe Allain, Dominique Bonneau Marie Bost, Bénédicte Gohier, Marie-Anne Guérid, Audrey Olivier, Julie Prouzet, Adriana Prundean, Clarisse Scherer-Gagou, Christophe Verny, Blandine Babiloni, Sabrina Debruxelles, Charlotte Duché, Cyril Goizet, Laetitia Jameau, Danielle Lafoucrière, Umberto Spampinato, Anne-Catherine Bachoud-Lévi, Farideh Badei, Lotfi Boudali, Catherine Bourdet, Laurent Cléret, Maryline Couette, Cécile Focseneanu, Laurie Lemoine, Graça Morgado, Mehdi Sebaiti, Claire Thiriez, Laetitia Vervoitte, Katia Youssov, Jean-Philippe Azulay, Christelle Chabot, Marie Delfini, Alexandre Eusebio, Frédérique Fluchere, Christine Garreau, Aicha Ghenam, Hélène Grosjean, Laura Mundler, Marielle Nowak, Roland Raseta, Maïté Bertrand, Fabienne Calvas, Samia Cheriet, Laurent Marquine, Michèle Pierre, Jérémie Pariente, Sandrine Rolland, Alice Seris, Valérie Vaquie, Christoph Michael Kosinski, Eva Milkereit, Daniela Probst, Kathrin Reetz, Christian Sass, Johannes Schiefer, Christiane Schlangen, Cornelius J Werner, Gisa Ellrichmann, Lennard Herrmann, Rainer Hoffmann, Barbara Kaminski, Carsten Saft, Kai Boelmans, Christos Ganos, Ines Goerendt, Walburgis Heinicke, Ute Hidding, Jan Lewerenz, Alexander Münchau, Michael Orth, Jenny Schmalfeld, Lars Stubbe, Simone Zittel, Gabriele Diercks, Dirk Dressler, Flverly Francis, Sabine Gayde-Stephan, Heike Gorzolla, Bianca Kramer, Rebecca Minschke, Christoph Schrader, Pawel Tacik, Natalie Bechtel, Heike Beckmann, Stefan Bohlen, Nicole Göpfert, Eva Hölzner, Herwig Lange, Ralf Reilmann, Stefanie Rohm, Silke Rumpf, Sigrun Schepers, Nathalia Weber, Michael Bachmeier, Matthias Dose, Nina Hofstetter, Ralf Marquard, Alzbeta Mühlbäck, Andrea Buck, Julia Connemann, Carolin Geitner, Andrea Kesse, Bernhard Landwehrmeyer, Franziska Lezius, Solveig Nepper, Anke Niess, Ariane Schneider, Daniela Schwenk, Sigurd Süssmuth, Sonja Trautmann, Patrick Weydt, Stephan Klebe, Thomas Musacchio, Christine Leypold, Kerstin Nöth, Claudia Cormio, Marina de Tommaso, Anna Rita Dellomonaco, Olimpia Difruscolo, Giovanni Franco, Vittorio Sciruicchio, Claudia Serpino, Michela Figorilli, Francesco Marrosu, Antonella Muroni, Valeria Piras, Melisa Vacca, Caterina Bartoli, Elisabetta Bertini, Fernanda Fortunato, Elena Ghelli, Andrea Ginestroni, Claudia Mechi, Marco Paganini, Silvia Piacentini, Silvia Pradella, Anna Maria Romoli, Sandro Sorbi, Giuseppe De Michele, Luigi Di Maio, Carlo Rinaldi, Marco Massarelli, Silvio Peluso, Alessandro Roca, Cinzia Valeria Russo, Pierpaolo Sorrentino, Elena Salvatore, Tecla Tucci, Milena Cannella, Valentina Codella, Francesca De Gregorio, Annunziata De Nicola, Francesca Elifani, Tiziana Martino, Francesca Lovo, Irene Mazzante, Martina Petrollini, Maria Simonelli, Ferdinando Squitieri, Maurizio Vezza, Barbara D'Alessio, Chiara Esposito, Giulia Coarelli, Michela Ferraldeschi, Marina Frontali, Gioia Jacopini, Giovanni Ristori, Silvia Romano, Monique S E van Hout, Jeroen P P van Vugt, A Marit de Weert, Marloes Verhoeven, Simon J A van den Bogaard, Eve M Dumas, Ellen P 't Hart, Milou Jacobs, Anne Kampstra, Anne Schoonderbeek, Nils Olav Aanonsen, Olaf Aaserud, Liv Barnett, Kathrine Bjørgo, Nancy Borgerød, Elisabeth Dramstad, Madeleine Fannemel, Jan Frich, Helen Gundersen, Per Gørvell, Kathrine Haggag, Cecilie Haggag Johannessen, Lars Retterstøl, Oddveig Rosby, Jutta Rummel, Alma Sikiric, Olga Solberg, Marleen van Walsem, Ragnhild Wehus, Artur Dziadkiewicz, Agnieszka Konkel, Ewa Narożańska, Malgorzata Nowak, Piotr Robowski, Emilia Sitek, Jaroslaw Slawek, Witold Soltan, Michal Szinwelski, Michał Arkuszewski, Magdalena Błaszczyk, Magdalena Boczarska-Jedynak, Ewelina Ciach-Wysocka, Agnieszka Gorzkowska, Barbara Jasińska-Myga, Aleksandra Kaczmarczyk, Gabriela Kłodowska-Duda, Grzegorz Opala, Monika Rudzińska, Daniel Stompel, Krzysztof Banaszkiewicz, Dorota Boćwińska, Kamila Bojakowska-Jaremek, Małgorzata Dec, Natalia Grabska, Malgorzata Krawczyk, Ewelina Kubowicz, Michalina Malec-Litwinowicz, Agata Stenwak, Andrzej Szczudlik, Elżbieta Szczygieł, Magdalena Wójcik, Anna Wasielewska, Jacek Anioła Anna Bryl, Anna Ciesielska, Aneta Klimberg, Jerzy Marcinkowski, Husam Samara, Justyna Sempołowicz, Bartłomiej Wiśniewski, Anna Gogol, Piotr Janik, Zygmunt Jamrozik, Anna Kaminska, Hubert Kwiecinski, Jakub Antczak, Katarzyna Jachinska, Wioletta Krysa, Maryla Rakowicz, Przemyslaw Richter, Rafal Rola, Danuta Ryglewicz, Halina Sienkiewicz-Jarosz, Iwona Stępniak, Anna Sułek, Elzbieta Zdzienicka, Karolina Ziora-Jakutowicz, Cristina Januário, Filipa Júlio, Ana Salgueiro, Miguel Coelho, Tiago Mendes, Mário Miguel Rosa, Anabela Valadas, Cristina Semedo, Ana Calado, Joana Morgado, Margarida Dias, Manuel Almeida, Carmen Durán Herrera, Patrocinio Garcia Moreno, Jordi Bas, Núria Busquets, Matilde Calopa, Serge Jaumà Classen, Nadia Rodríguez Dedichá, Miquel Aguilar Barbera, Sonia Arribas Pardo, Dolors Badenes Guia, Noemi Calzado, Laura Casas Hernanz, Juan Pablo Tartari Díaz-Zorita, Judit López Catena, Pilar Quiléz Ferrer, Gemma Tome Carruesco, Misericordia Floriach Robert, Cèlia Mareca Viladrich, Elvira Roca, Jesús Miguel Ruiz Idiago, Antonio Villa Riballo, Antonia Campolongo, Ramon Fernandez de Bobadilla, Jaime Kulisevsky Bojarsky, Javier Pagonabarraga, Jesus Perez Perez, Carolina Villa, Maria Angeles Acera Gil, Koldo Berganzo Corrales, Juan Carlos Gomez Esteban, Amaia González, Beatriz Tijero Merino, Esther Cubo, Natividad Mariscal, Sandra Gutierrez Romero, José Matías Arbelo, Rocío Malo de Molina, Idaira Martín, Juan Manuel Periañez, Beatriz Udaeta, Fernando Alonso-Frech, Belén Frades, Marina Ávila Villanueva, Maria Ascension Zea Sevilla, Fernando Alonso Frech, María Del Mar Fenollar, Rocío García-Ramos García, Clara Villanueva, Mónica Bascuñana, Marta Fatás Ventura, Juan García Caldentey, Guillermo García Ribas, Justo García de Yébenes, José Luis López-Sendón Moreno, Verónica Mañanes Barral, Cici Feliz Feliz, Pedro José García Ruíz, Ana García, Rosa Guerrero López, Antonio Herranz Bárcenas, Asunción Martínez-Descals, Angel Martínez Pueyo, Veronica Puertas Martin, Noelia Rodríguez Martínez, María José Sainz Artiga, Vicenta Sánchez, Javier Del Val Fernandez, Carmen Antúnez Almagro, Salvadora Manzanares, Juan Marín Muñoz, María Martirio Antequera Torres, Fuensanta Noguera Perea, Laura Vivancos Moreau, Sonia González, Luis Menéndez Guisasola, Carlos Salvador, René Ribacoba, Pablo Sánchez Lozano, Marta Para Prieto, Aránzazu Gorospe, Inés Legarda Ramirez, Penelope Navas Arques, Monica Rodriguez Lopera, Barbara Vives Pastor, Itziar Gaston, Maria Antonia Ramos-Arroyo, Maria Dolores Martinez-Jaurrieta, José Manuel García Moreno, Carolina Mendez Lucena, José Chacón Peña, Fátima Damas Hermoso, Eva Pacheco Cortegana, Luis Redondo, Cristina Melgar Fernandez, Maite Paredes Mata, Maria Dolores Romero Lemos, Maria Bosca, Juan Andres Burguera, Francisco Castera Brugada Carmen Peiró Vilaplana, Elena Bellosta Diago, Javier López Del Val, Laura Martinez Martinez, Elena López, Peter Berglund, Radu Constantinescu, Gunnel Fredlund, Ulrika Høsterey-Ugander, Liselotte Neleborn-Lingefjärd, Yanik Stebler, Alain Kaelin, Irene Romero, Michael Schüpbach, Sabine Weber Zaugg, Lorna Downie, Roisin Jack, Kirsty Matheson, Zosia Miedzybrodzka, Daniela Rae, Sheila A Simpson, Fiona Summers, Alexandra Ure, Vivien Vaughn, Shahbana Akhtar, Jenny Crooks, Adrienne Curtis, Jenny de Souza, John Piedad, Hugh Rickards, Jan Wright, Elizabeth Coulthard, Louise Gethin, Beverley Hayward, Kasia Sieradzan, Monica Busse, Cynthia Butcher, Stephen Dunnett, Catherine Clenaghan, Sarah Hunt, Lesley Jones, Una Jones, Hanan Khalil, Michael Owen, Kathleen Price, Anne Rosser, Peter Brockie, Jillian Foster, Nicola Johns, Sue McKenzie, Jean Rothery, Gareth Thomas, Shona Yates, Alyson Andrew, Julie Frost, Rupert Noad, Jeremy Cosgrove, Deena Gallantree, Stephanie Hamer, Emma Hobson, Stuart Jamieson, Alison Kraus, Mandy Longthorpe, Ivana Markova, Hannah Musgrave, Caroline Peacy, Ashok Raman, Liz Rowett, Jean Toscano, Sue Wild, Carole Clayton, Pam Yardumian, Heather Dipple, Dawn Freire- Patino, Caroline Hallam, Julia Middleton, Uruj Anjum, Jan Coebergh, Charlotte Eddy, Nayana Lahiri, Meriel McEntagart, Michael Patton, Maria Peterson, Sarah Rose, Thomasin Andrews, Stefanie Brown, Stefania Bruno, Elvina Chu, Karen Doherty, Charlotte Golding, Salman Haider, Davina Hensman, Monica Lewis, Marianne Novak, Aakta Patel, Joy Read, Nicola Robertson, Elisabeth Rosser, Sarah Tabrizi, Rachel Taylor, Thomas Warner, Edward Wild, Natalie Arran, Judith Bek, David Craufurd, Marianne Hare, Liz Howard, Susan Huson, Liz Johnson, Mary Jones, Ashok Krishnamoorthy, Helen Murphy, Emma Oughton, Lucy Partington-Jones, Andrea Sollom, Julie Snowden, Cheryl Stopford, Jennifer Thompson, Iris Trender-Gerhard, Nichola Verstraelen, Leann Westmoreland, Ginette Cass, Lynn Davidson, Jill Davison, Neil Fullerton, Katrina Holmes, Suresh Komati, Sharon McDonnell, Zeid Mohammed, Karen Morgan, Lois Savage, Baldev Singh, Josh Wood, Andrea H Nemeth, Gill Siuda, Ruth Valentine, Kathryn Dixon, Richard Armstrong, David Harrison, Max Hughes, Sandra Large, John O Donovan, Amy Palmer, Andrew Parkinson, Beverley Soltysiak, Leanne Timings, Josh Williams, Oliver Bandmann, Alyson Bradbury, Helen Fairtlough, Kay Fillingham, Isabella Foustanos, Paul Gill, Mbombe Kazoka, Kirsty O'Donovan, Louise Nevitt, Oliver Quarrell, Cat Taylor, Katherine Tidswell, Lesley Gowers, Kingsley Powell, Pamela Bethwaite, Rachel Edwards, Kathleen Fuller, Michelle Phillips, Univ Angers, Okina, E., Cubo, M. A., Ramos-Arroyo, S., Martinez-Horta, A., Martinez-Descall, S., Calvo, CAnne-Catherine Bachoud-Lévi, Gil-Polo, Rita Bentivoglio, Anna, Biunno, Ida, M Bonelli, Raphael, Burgunder, Jean-Marc, B Dunnett, Stephen, J Ferreira, Joaquim, J Handley, Olivia, Heiberg, Arvid, Illmann, Torsten, Bernhard Landwehrmeyer, G, Levey, Jamie, Ramos-Arroyo, Maria, E Nielsen, Jørgen, Pro Koivisto, Susana, Päivärinta, Markku, C Roos, Raymund A, Rojo Sebastián, Ana, J Tabrizi, Sarah, Vandenberghe, Wim, Verellen-Dumoulin, Christine, Uhrova, Tereza, Wahlström, Jan, Zaremba, Jacek, Baake, Verena, Barth, Katrin, Come, Adrien, Correia Guedes, Leonor, Maria Finisterra, Ana, Bascuñana Garde, Monica, Bos, Reineke, Betz, Sabrina, Callaghan, Jenny, Capodarca, Selene, Charpentier, Sébastien, Vieira da Silva, Wildson, Di Renzo, Martina, Ecker, Daniel, Fullam, Ruth, Genoves, Camille, Gilling, Mette, Hvalstedt, Carina, Held, Christine, Horta-Barba, Andrea, Koppers, Kerstin, Lamanna, Claudia, Laurà, Matilde, Martínez Descals, Asunción, Martinez-Horta, Saul, Mestre, Tiago, Minster, Sara, Monza, Daniela, Mütze, Lisanne, Oehmen, Martin, Padieu, Helene, Paterski, Laurent, Peppa, Nadia, Rindal, Beate, Rogers, Dawn, Røren, Niini, Šašinková, Pavla, Seliverstov, Yuri, Taylor, Catherine, Timewell, Erika, Townhill, Jenny, Trigo Cubillo, Patricia, R van Walsem, Marleen, Witjes-Ané, Marie-Noelle, Witkowski, Grzegorz, Wright, Abigail, Yudina, Elizaveta, Zielonka, Daniel, Zielonka, Eugeniusz, Zinzi, Paola, Minet, Cécile, Ribaï, Pascale, Van Paemel, Dominique, Hjermind, Lena, Jacobsen, Oda, Lindquist, Suzanne, Nielsen, Jørgen, Regeur, Lisbeth, Stockholm, Jette, Unmack Larsen, Ida, Vangsted-Hansen, Christina, Vinther-Jensen, Tua, Eklund, Pia, Hiivola, Heli, Hypponen, Hannele, Martikainen, Kirsti, Tuuha, Katri, Allain, Philippe, Bonneau Marie Bost, Dominique, Gohier, Bénédicte, Guérid, Marie-Anne, Olivier, Audrey, Prouzet, Julie, Prundean, Adriana, Scherer-Gagou, Clarisse, Verny, Christophe, Babiloni, Blandine, Debruxelles, Sabrina, Duché, Charlotte, Goizet, Cyril, Jameau, Laetitia, Lafoucrière, Danielle, Spampinato, Umberto, Bachoud-Lévi, Anne-Catherine, Badei, Farideh, Boudali, Lotfi, Bourdet, Catherine, Cléret, Laurent, Couette, Maryline, Focseneanu, Cécile, Lemoine, Laurie, Morgado, Graça, Sebaiti, Mehdi, Thiriez, Claire, Vervoitte, Laetitia, Youssov, Katia, Azulay, Jean-Philippe, Chabot, Christelle, Delfini, Marie, Eusebio, Alexandre, Fluchere, Frédérique, Garreau, Christine, Ghenam, Aicha, Grosjean, Hélène, Mundler, Laura, Nowak, Marielle, Raseta, Roland, Bertrand, Maïté, Calvas, Fabienne, Cheriet, Samia, Marquine, Laurent, Pierre, Michèle, Pariente, Jérémie, Rolland, Sandrine, Seris, Alice, Vaquie, Valérie, Michael Kosinski, Christoph, Milkereit, Eva, Probst, Daniela, Reetz, Kathrin, Sass, Christian, Schiefer, Johanne, Schlangen, Christiane, J Werner, Corneliu, Ellrichmann, Gisa, Herrmann, Lennard, Hoffmann, Rainer, Kaminski, Barbara, Saft, Carsten, Boelmans, Kai, Ganos, Christo, Goerendt, Ine, Heinicke, Walburgi, Hidding, Ute, Lewerenz, Jan, Münchau, Alexander, Orth, Michael, Schmalfeld, Jenny, Stubbe, Lar, Zittel, Simone, Diercks, Gabriele, Dressler, Dirk, Francis, Flverly, Gayde-Stephan, Sabine, Gorzolla, Heike, Kramer, Bianca, Minschke, Rebecca, Schrader, Christoph, Tacik, Pawel, Bechtel, Natalie, Beckmann, Heike, Bohlen, Stefan, Göpfert, Nicole, Hölzner, Eva, Lange, Herwig, Reilmann, Ralf, Rohm, Stefanie, Rumpf, Silke, Schepers, Sigrun, Weber, Nathalia, Bachmeier, Michael, Dose, Matthia, Hofstetter, Nina, Marquard, Ralf, Mühlbäck, Alzbeta, Buck, Andrea, Connemann, Julia, Geitner, Carolin, Kesse, Andrea, Landwehrmeyer, Bernhard, Lezius, Franziska, Nepper, Solveig, Niess, Anke, Schneider, Ariane, Schwenk, Daniela, Süssmuth, Sigurd, Trautmann, Sonja, Weydt, Patrick, Klebe, Stephan, Musacchio, Thoma, Leypold, Christine, Nöth, Kerstin, Cormio, Claudia, de Tommaso, Marina, Rita Dellomonaco, Anna, Difruscolo, Olimpia, Franco, Giovanni, Sciruicchio, Vittorio, Serpino, Claudia, Figorilli, Michela, Marrosu, Francesco, Muroni, Antonella, Piras, Valeria, Vacca, Melisa, Bartoli, Caterina, Bertini, Elisabetta, Fortunato, Fernanda, Ghelli, Elena, Ginestroni, Andrea, Mechi, Claudia, Paganini, Marco, Piacentini, Silvia, Pradella, Silvia, Maria Romoli, Anna, Sorbi, Sandro, DE MICHELE, Giuseppe, Di Maio, Luigi, Rinaldi, Carlo, Massarelli, Marco, Peluso, Silvio, Roca, Alessandro, Russo, CINZIA VALERIA, Sorrentino, Pierpaolo, Salvatore, Elena, Tucci, Tecla, Cannella, Milena, Codella, Valentina, De Gregorio, Francesca, De Nicola, Annunziata, Elifani, Francesca, Martino, Tiziana, Lovo, Francesca, Mazzante, Irene, Petrollini, Martina, Simonelli, Maria, Squitieri, Ferdinando, Vezza, Maurizio, D'Alessio, Barbara, Esposito, Chiara, Coarelli, Giulia, Ferraldeschi, Michela, Frontali, Marina, Jacopini, Gioia, Ristori, Giovanni, Romano, Silvia, E van Hout, Monique S, P van Vugt, Jeroen P, Marit de Weert, A, Verhoeven, Marloe, A van den Bogaard, Simon J, M Dumas, Eve, P 't Hart, Ellen, Jacobs, Milou, Kampstra, Anne, Schoonderbeek, Anne, Olav Aanonsen, Nil, Aaserud, Olaf, Barnett, Liv, Bjørgo, Kathrine, Borgerød, Nancy, Dramstad, Elisabeth, Fannemel, Madeleine, Frich, Jan, Gundersen, Helen, Gørvell, Per, Haggag, Kathrine, Haggag Johannessen, Cecilie, Retterstøl, Lar, Rosby, Oddveig, Rummel, Jutta, Sikiric, Alma, Solberg, Olga, van Walsem, Marleen, Wehus, Ragnhild, Dziadkiewicz, Artur, Konkel, Agnieszka, Narożańska, Ewa, Nowak, Malgorzata, Robowski, Piotr, Sitek, Emilia, Slawek, Jaroslaw, Soltan, Witold, Szinwelski, Michal, Arkuszewski, Michał, Błaszczyk, Magdalena, Boczarska-Jedynak, Magdalena, Ciach-Wysocka, Ewelina, Gorzkowska, Agnieszka, Jasińska-Myga, Barbara, Kaczmarczyk, Aleksandra, Kłodowska-Duda, Gabriela, Opala, Grzegorz, Rudzińska, Monika, Stompel, Daniel, Banaszkiewicz, Krzysztof, Boćwińska, Dorota, Bojakowska-Jaremek, Kamila, Dec, Małgorzata, Grabska, Natalia, Krawczyk, Malgorzata, Kubowicz, Ewelina, Malec-Litwinowicz, Michalina, Stenwak, Agata, Szczudlik, Andrzej, Szczygieł, Elżbieta, Wójcik, Magdalena, Wasielewska, Anna, Anioła Anna Bryl, Jacek, Ciesielska, Anna, Klimberg, Aneta, Marcinkowski, Jerzy, Samara, Husam, Sempołowicz, Justyna, Wiśniewski, Bartłomiej, Gogol, Anna, Janik, Piotr, Jamrozik, Zygmunt, Kaminska, Anna, Kwiecinski, Hubert, Antczak, Jakub, Jachinska, Katarzyna, Krysa, Wioletta, Rakowicz, Maryla, Richter, Przemyslaw, Rola, Rafal, Ryglewicz, Danuta, Sienkiewicz-Jarosz, Halina, Stępniak, Iwona, Sułek, Anna, Zdzienicka, Elzbieta, Ziora-Jakutowicz, Karolina, Januário, Cristina, Júlio, Filipa, Salgueiro, Ana, Coelho, Miguel, Mendes, Tiago, Miguel Rosa, Mário, Valadas, Anabela, Semedo, Cristina, Calado, Ana, Morgado, Joana, Dias, Margarida, Almeida, Manuel, Durán Herrera, Carmen, Garcia Moreno, Patrocinio, Bas, Jordi, Busquets, Núria, Calopa, Matilde, Jaumà Classen, Serge, Rodríguez Dedichá, Nadia, Aguilar Barbera, Miquel, Arribas Pardo, Sonia, Badenes Guia, Dolor, Calzado, Noemi, Casas Hernanz, Laura, Pablo Tartari Díaz-Zorita, Juan, López Catena, Judit, Quiléz Ferrer, Pilar, Tome Carruesco, Gemma, Floriach Robert, Misericordia, Mareca Viladrich, Cèlia, Roca, Elvira, Miguel Ruiz Idiago, Jesú, Villa Riballo, Antonio, Campolongo, Antonia, Fernandez de Bobadilla, Ramon, Kulisevsky Bojarsky, Jaime, Pagonabarraga, Javier, Perez Perez, Jesu, Villa, Carolina, Angeles Acera Gil, Maria, Berganzo Corrales, Koldo, Carlos Gomez Esteban, Juan, González, Amaia, Tijero Merino, Beatriz, Cubo, Esther, Mariscal, Natividad, Gutierrez Romero, Sandra, Matías Arbelo, José, Malo de Molina, Rocío, Martín, Idaira, Manuel Periañez, Juan, Udaeta, Beatriz, Alonso-Frech, Fernando, Frades, Belén, Ávila Villanueva, Marina, Ascension Zea Sevilla, Maria, Alonso Frech, Fernando, Del Mar Fenollar, María, García-Ramos García, Rocío, Villanueva, Clara, Bascuñana, Mónica, Fatás Ventura, Marta, García Caldentey, Juan, García Ribas, Guillermo, García de Yébenes, Justo, Luis López-Sendón Moreno, José, Mañanes Barral, Verónica, Feliz Feliz, Cici, José García Ruíz, Pedro, García, Ana, Guerrero López, Rosa, Herranz Bárcenas, Antonio, Martínez-Descals, Asunción, Martínez Pueyo, Angel, Puertas Martin, Veronica, Rodríguez Martínez, Noelia, José Sainz Artiga, María, Sánchez, Vicenta, Del Val Fernandez, Javier, Antúnez Almagro, Carmen, Manzanares, Salvadora, Marín Muñoz, Juan, Martirio Antequera Torres, María, Noguera Perea, Fuensanta, Vivancos Moreau, Laura, González, Sonia, Menéndez Guisasola, Lui, Salvador, Carlo, Ribacoba, René, Sánchez Lozano, Pablo, Para Prieto, Marta, Gorospe, Aránzazu, Legarda Ramirez, Iné, Navas Arques, Penelope, Rodriguez Lopera, Monica, Vives Pastor, Barbara, Gaston, Itziar, Antonia Ramos-Arroyo, Maria, Dolores Martinez-Jaurrieta, Maria, Manuel García Moreno, José, Mendez Lucena, Carolina, Chacón Peña, José, Damas Hermoso, Fátima, Pacheco Cortegana, Eva, Redondo, Lui, Melgar Fernandez, Cristina, Paredes Mata, Maite, Dolores Romero Lemos, Maria, Bosca, Maria, Andres Burguera, Juan, Castera Brugada Carmen Peiró Vilaplana, Francisco, Bellosta Diago, Elena, López Del Val, Javier, Martinez Martinez, Laura, López, Elena, Berglund, Peter, Constantinescu, Radu, Fredlund, Gunnel, Høsterey-Ugander, Ulrika, Neleborn-Lingefjärd, Liselotte, Stebler, Yanik, Kaelin, Alain, Romero, Irene, Schüpbach, Michael, Weber Zaugg, Sabine, Downie, Lorna, Jack, Roisin, Matheson, Kirsty, Miedzybrodzka, Zosia, Rae, Daniela, A Simpson, Sheila, Summers, Fiona, Ure, Alexandra, Vaughn, Vivien, Akhtar, Shahbana, Crooks, Jenny, Curtis, Adrienne, de Souza, Jenny, Piedad, John, Rickards, Hugh, Wright, Jan, Coulthard, Elizabeth, Gethin, Louise, Hayward, Beverley, Sieradzan, Kasia, Busse, Monica, Butcher, Cynthia, Dunnett, Stephen, Clenaghan, Catherine, Hunt, Sarah, Jones, Lesley, Jones, Una, Khalil, Hanan, Owen, Michael, Price, Kathleen, Rosser, Anne, Brockie, Peter, Foster, Jillian, Johns, Nicola, Mckenzie, Sue, Rothery, Jean, Thomas, Gareth, Yates, Shona, Andrew, Alyson, Frost, Julie, Noad, Rupert, Cosgrove, Jeremy, Gallantree, Deena, Hamer, Stephanie, Hobson, Emma, Jamieson, Stuart, Kraus, Alison, Longthorpe, Mandy, Markova, Ivana, Musgrave, Hannah, Peacy, Caroline, Raman, Ashok, Rowett, Liz, Toscano, Jean, Wild, Sue, Clayton, Carole, Yardumian, Pam, Dipple, Heather, Freire- Patino, Dawn, Hallam, Caroline, Middleton, Julia, Anjum, Uruj, Coebergh, Jan, Eddy, Charlotte, Lahiri, Nayana, Mcentagart, Meriel, Patton, Michael, Peterson, Maria, Rose, Sarah, Andrews, Thomasin, Brown, Stefanie, Bruno, Stefania, Chu, Elvina, Doherty, Karen, Golding, Charlotte, Haider, Salman, Hensman, Davina, Lewis, Monica, Novak, Marianne, Patel, Aakta, Read, Joy, Robertson, Nicola, Rosser, Elisabeth, Tabrizi, Sarah, Taylor, Rachel, Warner, Thoma, Wild, Edward, Arran, Natalie, Bek, Judith, Craufurd, David, Hare, Marianne, Howard, Liz, Huson, Susan, Johnson, Liz, Jones, Mary, Krishnamoorthy, Ashok, Murphy, Helen, Oughton, Emma, Partington-Jones, Lucy, Sollom, Andrea, Snowden, Julie, Stopford, Cheryl, Thompson, Jennifer, Trender-Gerhard, Iri, Verstraelen, Nichola, Westmoreland, Leann, Cass, Ginette, Davidson, Lynn, Davison, Jill, Fullerton, Neil, Holmes, Katrina, Komati, Suresh, Mcdonnell, Sharon, Mohammed, Zeid, Morgan, Karen, Savage, Loi, Singh, Baldev, Wood, Josh, H Nemeth, Andrea, Siuda, Gill, Valentine, Ruth, Dixon, Kathryn, Armstrong, Richard, Harrison, David, Hughes, Max, Large, Sandra, O Donovan, John, Palmer, Amy, Parkinson, Andrew, Soltysiak, Beverley, Timings, Leanne, Williams, Josh, Bandmann, Oliver, Bradbury, Alyson, Fairtlough, Helen, Fillingham, Kay, Foustanos, Isabella, Gill, Paul, Kazoka, Mbombe, O'Donovan, Kirsty, Nevitt, Louise, Quarrell, Oliver, Taylor, Cat, Tidswell, Katherine, Gowers, Lesley, Powell, Kingsley, Bethwaite, Pamela, Edwards, Rachel, Fuller, Kathleen, Phillips, Michelle, Cubo, E., Ramos-Arroyo, M. A., Martinez-Horta, S., Martinez-Descalls, A., Russo, C. V., Calvo, S., Gil-Polo, C., Biologie Neurovasculaire et Mitochondriale Intégrée (BNMI), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université d'Angers (UA), Ramos-Arroyo, María A., Martínez-Descalls, Asunción, Calvo, Sara, and Gil-Polo, Cecilia
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0301 basic medicine ,Registrie ,Adult ,Male ,medicine.medical_specialty ,Aging ,Heterozygote ,Genetic counseling ,Motor Disorders ,Disease ,Severity of Illness Index ,03 medical and health sciences ,Cognition Disorder ,0302 clinical medicine ,Trinucleotide Repeats ,Internal medicine ,medicine ,Humans ,Registries ,Allele ,Motor Disorder ,Alleles ,Huntingtin Protein ,[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology ,business.industry ,Medicine (all) ,Trinucleotide Repeat ,Cognition ,Genetic Status ,Middle Aged ,Phenotype ,Europe ,Settore MED/26 - NEUROLOGIA ,030104 developmental biology ,Huntington Disease ,Case-Control Studies ,Cohort ,medicine (all) ,neurology (clinical) ,controlled clinical trial (topic) ,Quality of Life ,Female ,Neurology (clinical) ,business ,Case-Control Studie ,Cognition Disorders ,030217 neurology & neurosurgery ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,Human - Abstract
International audience; OBJECTIVE: There is controversy about the clinical consequences of intermediate alleles (IAs) in Huntington disease (HD). The main objective of this study was to establish the clinical manifestations of IA carriers for a prospective, international, European HD registry.METHODS: We assessed a cohort of participants at risk with RESULTS: Of 12,190 participants, 657 (5.38%) with CONCLUSIONS: Although aging worsened the UHDRS scores independently of the genetic status, IAs might confer a late-onset abnormal motor and cognitive phenotype. These results might have important implications for genetic counseling.CLINICALTRIALSGOV IDENTIFIER: NCT01590589.
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- 2016
39. Comparing the coverage, recall, and precision of searches for 120 systematic reviews in Embase, MEDLINE, and Google Scholar: a prospective study
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Wichor M. Bramer, Bianca Kramer, Dean Giustini, and Erasmus MC other
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Post hoc ,MEDLINE ,Medicine (miscellaneous) ,Review Literature as Topic ,Full coverage ,Search engine ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Humans ,030212 general & internal medicine ,Prospective Studies ,Prospective cohort study ,Information retrieval ,Recall ,business.industry ,Research ,Information storage and retrieval ,Bibliographic databases ,Databases, Bibliographic ,Systematic review ,Sensitivity and specificity ,Precision and recall ,business ,030217 neurology & neurosurgery - Abstract
Background: Previously, we reported on the low recall of Google Scholar (GS) for systematic review (SR) searching. Here, we test our conclusions further in a prospective study by comparing the coverage, recall, and precision of SR search strategies previously performed in Embase, MEDLINE, and GS. Methods The original search results from Embase and MEDLINE and the first 1000 results of GS for librarian-mediated SR searches were recorded. Once the inclusion-exclusion process for the resulting SR was complete, search results from all three databases were screened for the SR’s included references. All three databases were then searched post hoc for included references not found in the original search results. Results We checked 4795 included references from 120 SRs against the original search results. Coverage of GS was high (97.2 %) but marginally lower than Embase and MEDLINE combined (97.5 %). MEDLINE on its own achieved 92.3 % coverage. Total recall of Embase/MEDLINE combined was 81.6 % for all included references, compared to GS at 72.8 % and MEDLINE alone at 72.6 %. However, only 46.4 % of the included references were among the downloadable first 1000 references in GS. When examining data for each SR, the traditional databases’ recall was better than GS, even when taking into account included references listed beyond the first 1000 search results. Finally, precision of the first 1000 references of GS is comparable to searches in Embase and MEDLINE combined. Conclusions Although overall coverage and recall of GS are high for many searches, the database does not achieve full coverage as some researchers found in previous research. Further, being able to view only the first 1000 records in GS severely reduces its recall percentages. If GS would enable the browsing of records beyond the first 1000, its recall would increase but not sufficiently to be used alone in SR searching. Time needed to screen results would also increase considerably. These results support our assertion that neither GS nor one of the other databases investigated, is on its own, an acceptable database to support systematic review searching.
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- 2016
40. Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration
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Karun K. Singh, Bianca Kramer, David L. Kaplan, Michael E. Greenberg, Freda D. Miller, Elizabeth J. Hong, and Katya J. Park
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Nervous system ,Cholera Toxin ,Stilbamidines ,Green Fluorescent Proteins ,Mice, Transgenic ,Superior Cervical Ganglion ,Biology ,Receptor, Nerve Growth Factor ,Potassium Chloride ,Neuroscientist ,Rats, Sprague-Dawley ,Mice ,Pioneer axon ,Neurotrophic factors ,Nerve Growth Factor ,medicine ,Animals ,Low-affinity nerve growth factor receptor ,Drug Interactions ,Visual Pathways ,Enzyme Inhibitors ,Axon ,Cells, Cultured ,Neurons ,Dose-Response Relationship, Drug ,Brain-Derived Neurotrophic Factor ,General Neuroscience ,fungi ,Gene Expression Regulation, Developmental ,Axotomy ,Axons ,Oligodendrocyte ,Rats ,Mice, Inbred C57BL ,medicine.anatomical_structure ,Animals, Newborn ,nervous system ,Nerve Degeneration ,sense organs ,Neuron ,Neuroscience - Abstract
The mechanisms that regulate the pruning of mammalian axons are just now being elucidated. Here, we describe a mechanism by which, during developmental sympathetic axon competition, winning axons secrete brain-derived neurotrophic factor (BDNF) in an activity-dependent fashion, which binds to the p75 neurotrophin receptor (p75NTR) on losing axons to cause their degeneration and, ultimately, axon pruning. Specifically, we found that pruning of rat and mouse sympathetic axons that project to the eye requires both activity-dependent BDNF and p75NTR. p75NTR and BDNF are also essential for activity-dependent axon pruning in culture, where they mediate pruning by directly causing axon degeneration. p75NTR, which is enriched in losing axons, causes axonal degeneration by suppressing TrkA-mediated signaling that is essential for axonal maintenance. These data provide a mechanism that explains how active axons can eliminate less-active, competing axons during developmental pruning by directly promoting p75NTR-mediated axonal degeneration.
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- 2008
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41. Regulation of neurons in the suprachiasmatic nucleus of Xenopus laevis
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Nicole J. Westphal, Ji-Ying Song, Bianca Kramer, Eric W. Roubos, and Bruce G. Jenks
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medicine.medical_specialty ,Time Factors ,Physiology ,Synaptobrevin ,Xenopus ,Neuropeptide ,Inhibitory postsynaptic potential ,Models, Biological ,Biochemistry ,R-SNARE Proteins ,Xenopus laevis ,chemistry.chemical_compound ,Internal medicine ,medicine ,Animals ,Neuropeptide Y ,Neurotransmitter ,Molecular Biology ,Neurons ,Microscopy, Confocal ,biology ,Suprachiasmatic nucleus ,Membrane Proteins ,biology.organism_classification ,Neuropeptide Y receptor ,Immunohistochemistry ,Cell biology ,Microscopy, Electron ,medicine.anatomical_structure ,Endocrinology ,chemistry ,Synapses ,Suprachiasmatic Nucleus ,Soma ,Peptides - Abstract
In the amphibian Xenopus laevis, suprachiasmatic melanotrope-inhibiting neurons (SMINs) play an important role in the regulation of the background adaptation process. In this study, we investigated the innervation of the SMINs at the light- and electron- microscopical level. Immunocytochemistry in combination with confocal laser scanning microscopy revealed co-existence of neuropeptide Y (NPY) and synaptobrevin in spots in the direct vicinity of the SMINs, suggesting the existence of NPY-containing synapses on these cells. At the ultrastructural level, the SMINs showed a high degree of plasticity, containing more electron-dense vesicles and a larger extent of RER in white- than in black-adapted animals. In black-adapted animals, symmetric synapses (Gray type II) were observed on the soma of the SMINs, suggesting an inhibitory input to these cells. The synaptic profiles contained electron-lucent and electron-dense vesicles, indicating the involvement of both a classical neurotransmitter and a neuropeptide (possibly NPY) in this input. In white-adapted animals, synapses were only found at some distance from the SMIN somata. Our findings indicate a striking plasticity of the innervation of the SMINs in relation to background adaptation and support the hypothesis that the SMINs are innervated by NPY-containing interneurons that inhibit SMIN activity in black-adapted animals.
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- 2002
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42. Evidence that Brain-Derived Neurotrophic Factor Acts as an Autocrine Factor on Pituitary Melanotrope Cells of Xenopus laevis
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Bianca Kramer, Eric W. Roubos, Bruce G. Jenks, Marcel W. Coolen, P. M. J. M. Cruijsen, D. T. W. M. Ouwens, and Gerard J.M. Martens
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medicine.medical_specialty ,Pituitary gland ,Pro-Opiomelanocortin ,Blotting, Western ,Immunocytochemistry ,Xenopus ,Skin Pigmentation ,In situ hybridization ,Xenopus laevis ,Endocrinology ,Neurotrophic factors ,Internal medicine ,medicine ,Animals ,RNA, Messenger ,Microscopy, Immunoelectron ,Autocrine signalling ,In Situ Hybridization ,Brain Chemistry ,Melanins ,Brain-derived neurotrophic factor ,biology ,Reverse Transcriptase Polymerase Chain Reaction ,Brain-Derived Neurotrophic Factor ,biology.organism_classification ,Adaptation, Physiological ,Immunohistochemistry ,Up-Regulation ,Autocrine Communication ,Light intensity ,medicine.anatomical_structure ,nervous system ,alpha-MSH ,Pituitary Gland ,Electrophoresis, Polyacrylamide Gel - Abstract
We have investigated the physiological regulation and functional significance of brain-derived neurotrophic factor (BDNF) in the endocrine melanotrope cells of the pituitary pars intermedia of the amphibian Xenopus laevis, which can adapt its skin color to the light intensity of its environment. In black-adapted animals, melanotrope cells produce and release α-melanophore-stimulating hormone (α-MSH). In white-adapted animals, the activity of melanotrope cells is inhibited by neuronal input. Using Western blotting and immunocytochemistry at the light and electron microscopical level, we have detected both the BDNF precursor and the mature BDNF protein in Xenopus melanotrope cells. In situ hybridization and RT-PCR revealed the presence of BDNF mRNA in the pituitary pars intermedia, indicating that BDNF is synthesized in the melanotropes. Real-time quantitative RT-PCR showed that levels of BDNF mRNA in melanotrope cells are about 25 times higher in black- than in white-adapted animals. Although there is no difference in the amount of stored mature BDNF, the amount of BDNF precursor protein is 3.5 times higher in melanotropes of black-adapted animals than in those of white-adapted animals. These data indicate that BDNF mRNA expression and BDNF biosynthesis are up-regulated in active melanotrope cells. Because immunoelectron microscopy showed that BDNF is located in melanotrope secretory granules, BDNF is probably coreleased with α-MSH via the regulated secretory pathway. Superfusion and 3H-amino acid incorporation studies demonstrated that BDNF stimulates the release of α-MSH and the biosynthesis of its precursor protein, POMC. Our results provide evidence that BDNF regulates the activity of Xenopus melanotrope cells in an autocrine fashion.
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- 2002
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43. Dynamics and plasticity of peptidergic control centres in the retino-brain-pituitary system of Xenopus laevis
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R. Ubink, Bruce G. Jenks, R. Tuinhof, E.W. Roubos, Sharon M. Kolk, Bianca Kramer, and C.A.F.M. Berghs
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Pituitary gland ,Histology ,Light ,Xenopus ,Neurophysiology ,Biology ,Retina ,Xenopus laevis ,Neuroplasticity ,medicine ,Animals ,Receptor ,Instrumentation ,Neuronal Plasticity ,Brain ,Translation (biology) ,Pars intermedia ,biology.organism_classification ,Adaptation, Physiological ,Medical Laboratory Technology ,medicine.anatomical_structure ,alpha-MSH ,Pituitary Gland ,Second messenger system ,Anatomy ,Signal transduction ,Neuroscience - Abstract
Contains fulltext : 185617.pdf (Publisher’s version ) (Closed access) This review deals particularly with the recent literature on the structural and functional aspects of the retino-brain-pituitary system that controls the physiological process of background adaptation in the aquatic toad Xenopus laevis. Taking together the large amount of multidisciplinary data, a consistent picture emerges of a highly plastic system that efficiently responds to changes in the environmental light condition by releasing POMC-derived peptides, such as the peptide alpha-melanophore-stimulating hormone (alpha-MSH), into the circulation. This plasticity is exhibited by both the central nervous system and the pituitary pars intermedia, at the level of molecules, subcellular structures, synapses, and cells. Signal transduction in the pars intermedia of the pituitary gland of Xenopus laevis appears to be a complex event, involving various environmental factors (e.g., light and temperature) that act via distinct brain centres and neuronal messengers converging on the melanotrope cells. In the melanotropes, these messages are translated by specific receptors and second messenger systems, in particular via Ca(2+) oscillations, controlling main secretory events such as gene transcription, POMC-precursor translation and processing, posttranslational peptide modifications, and release of a bouquet of POMC-derived peptides. In conclusion, the Xenopus hypothalamo-hypophyseal system involved in background adaptation reveals how neuronal plasticity at the molecular, cellular and organismal levels, enable an organism to respond adequately to the continuously changing environmental factors demanding physiological adaptation.
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- 2001
44. p75 nerve growth factor receptor is important for retrograde transport of neurotrophins in adult cholinergic basal forebrain neurons
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T Hagg, C.E.E.M Van der Zee, and Bianca Kramer
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medicine.medical_specialty ,Biological Transport, Active ,Hippocampus ,Receptor, Nerve Growth Factor ,Injections ,Mice ,Prosencephalon ,Reference Values ,Neurotrophic factors ,Internal medicine ,medicine ,Animals ,Low-affinity nerve growth factor receptor ,Nerve Growth Factors ,Cholinergic neuron ,Cell Size ,Mice, Knockout ,Neurons ,Basal forebrain ,biology ,General Neuroscience ,Biological Transport ,Choline acetyltransferase ,Endocrinology ,Nerve growth factor ,Cholinergic Fibers ,nervous system ,biology.protein ,Cholinergic ,Septum Pellucidum ,Neurotrophin - Abstract
The role of the p75 nerve growth factor receptor in the retrograde transport of neurotrophins in the adult CNS was investigated by comparing the transport of 125I-labeled neurotrophins by normal and p75 nerve growth factor receptor-deficient cholinergic septohippocampal neurons. In control mice, nerve growth factor was selectively transported from the hippocampal formation to the cholinergic neurons in the septum. Nerve growth factor labeling was found in three to four times as many septal cholinergic neuronal cell bodies than labeling for neurotrophin-3 or neurotrophin-4/5, and transported brain-derived neurotrophic factor was barely detectable. Cells were considered as labeled when the number of grains per cell exceeded five times background. In p75 nerve growth factor receptor-deficient mice, the number of cholinergic neurons labeled with each of the neurotrophins was reduced by 85–95%. Retrograde labeling of septohippocampal neurons with Fluorogold was not obviously reduced in p75 nerve growth factor receptor-deficient mice, suggesting that general transport mechanisms were not impaired. Despite the reduced neurotrophin transport, cholinergic neurons of p75 nerve growth factor receptor-deficient mice were larger than controls and had an apparently normal density of immunostaining for choline acetyltransferase. Since nerve growth factor is reportedly involved in size regulation and choline acetyltransferase expression, this raises the possibility that the retrograde transport itself is not essential for these events. Thus, p75 nerve growth factor receptor plays an important, although not exclusive, role in the transport of neurotrophins by cholinergic basal forebrain neurons, and retrograde transport of nerve growth factor may not be needed for regulating certain cellular processes.
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- 1999
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45. Views on innovation - The scholarly communication landscape and changing research workflows.
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Jeroen Bosman, Bianca Kramer, Jeroen Bosman, and Bianca Kramer
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- 2016
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46. Expression of carp-cdx1, a caudal homolog, in embryos of the carp, Cyprinus carpio
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H. Schipper, J. Samallo, Carine Stevens, H.W.J. Stroband, Bianca Kramer, L.P.M. Timmermans, and Geertruy te Kronnie
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biology ,cDNA library ,Lateral plate mesoderm ,Homeobox A1 ,Epiboly ,biology.organism_classification ,Molecular biology ,Gastrulation ,Fish ,Gastrulation Axial patterning ,Experimentele diermorfologie en celbiologie ,Homeobox gene ,WIAS ,Genetics ,Homeobox ,CDX2 ,Experimental Animal Morphology and Cell Biology ,Zebrafish ,Developmental Biology - Abstract
A carp caudal cDNA of 1.3 kb was cloned after screening an early segmentation stage cDNA library with a probe produced by PCR using conserved homeobox sequences as primers and genomic DNA as template. The homeobox gene was called carp-cdxl. The gene appears highly similar to other vertebrate caudal homologs, especially the zebrafish gene cdx(Zf-cad). The possible relationship to homeobox genes within the Hox-C gene complexes is discussed. A weak expression of the gene, detected by in situ hybridization, was found shortly before gastrulation (at 25% epiboly) in cells likely to have a posterior fate. During gastrulation expression became stronger. At the early segmentation stage, cells of the neural keel in the area of the prospective spinal cord expressed the gene. During the progression of segmentation, expression retracted in a caudal direction. The tailbud expressed the gene throughout, but the somites lost expression shortly after their formation. Only the most lateral mesoderm cells maintained expression in the trunk area. Carp-cdxl was also expressed in the endoderm. At 24 h after fertilization the gene was only expressed in the tailbud. At 48 h, no expression could be detected. The expression pattern suggests a function for carp-cdxl in gastrulation and patterning along the anterior-posterior axis of the embryo.
- Published
- 1995
- Full Text
- View/download PDF
47. The role of brain-derived neurotrophic factor in the regulation of cell growth and gene expression in melanotrope cells of xenopus laevis
- Author
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Miyuki Kuribara, Eric W. Roubos, Bruce G. Jenks, Wim J.J.M. Scheenen, Bianca Kramer, and Adhanet H. Kidane
- Subjects
Pituitary gland ,medicine.medical_specialty ,Melanotrophs ,Xenopus ,Gene Expression ,Neurophysiology ,Tropomyosin receptor kinase B ,Xenopus laevis ,Endocrinology ,Neurotrophic factors ,Internal medicine ,medicine ,Animals ,Autocrine signalling ,Brain-derived neurotrophic factor ,biology ,Brain-Derived Neurotrophic Factor ,Pars intermedia ,biology.organism_classification ,medicine.anatomical_structure ,Membrane transport and intracellular motility Renal disorder [NCMLS 5] ,nervous system ,biology.protein ,Animal Science and Zoology ,Neurotrophin - Abstract
Contains fulltext : 103841.pdf (Publisher’s version ) (Closed access) Brain-derived neurotrophic factor (BDNF) is, despite its name, also found outside the central nervous system (CNS), but the functional significance of this observation is largely unknown. This review concerns the expression of BDNF in the pituitary gland. While the presence of the neurotrophin in the mammalian pituitary gland is well documented its functional significance remains obscure. Studies on the pars intermedia of the pituitary of the amphibian Xenopus laevis have shown that BDNF is produced by the neuroendocrine melanotrope cells, its expression is physiologically regulated, and the melanotrope cells themselves express receptors for the neurotrophin. The neurotrophin has been shown to act as an autocrine factor on the melanotrope to promote cell growth and regulate gene expression. In doing so BDNF supports the physiological function of the cell to produce and release alpha-melanophore-stimulating hormone for the purpose of adjusting the animal's skin color to that of its background. 7 p.
- Published
- 2012
48. Empirical librarianship - template kaartjes (nov 2015)
- Author
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Bianca Kramer, Jeroen Bosman, Bianca Kramer, and Jeroen Bosman
- Published
- 2015
- Full Text
- View/download PDF
49. 101 Innovations in Scholarly Communication - addendum Assessment (October 2015)
- Author
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Bianca Kramer, Jeroen Bosman, Bianca Kramer, and Jeroen Bosman
- Published
- 2015
- Full Text
- View/download PDF
50. Information retrieval and literature searching in today's information landscape
- Author
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Bianca Kramer
- Subjects
Information retrieval ,Computer science ,Online search ,Information landscape ,Key (cryptography) ,Data science ,Literature searching ,Semantic Web ,Field (computer science) - Abstract
In this day and age of exponentially growing amounts of scientific information, the ability to perform efficient literature searches is a key skill for students and scientist. This review covers essential aspects of literature searching: devising a search strategy and selecting sources to search. Examples will be drawn from the field of biomedical research in general and evidence-based medicine in particular. In addition, the implications of the semantic web, Web2.0 and Open Access on literature searching will be discussed.
- Published
- 2009
- Full Text
- View/download PDF
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